7 research outputs found

    Os paraguaios na construção do Extremo Oeste do Brasil, 1870-1935

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    Com relação às recentes migrações em massa de latino-americanos para regiões do hemisfério anteriormente remotas, um dos aspectos mais importantes consiste no impacto que essas migrações tiveram sobre áreas de fronteiras internacionais. Entretanto, com exceção da fronteira entre os Estados Unidos e o México, a análise histórica desse processo, reconhecidamente complexo, encontra-se ainda em sua infância, e poucos observadores desenvolveram bases teóricas satisfatórias para explicá-lo

    Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication

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    Advances in genome technology have facilitated a new understanding of the historical and genetic processes crucial to rapid phenotypic evolution under domestication1, 2. To understand the process of dog diversification better, we conducted an extensive genome-wide survey of more than 48,000 single nucleotide polymorphisms in dogs and their wild progenitor, the grey wolf. Here we show that dog breeds share a higher proportion of multi-locus haplotypes unique to grey wolves from the Middle East, indicating that they are a dominant source of genetic diversity for dogs rather than wolves from east Asia, as suggested by mitochondrial DNA sequence data3. Furthermore, we find a surprising correspondence between genetic and phenotypic/functional breed groupings but there are exceptions that suggest phenotypic diversification depended in part on the repeated crossing of individuals with novel phenotypes. Our results show that Middle Eastern wolves were a critical source of genome diversity, although interbreeding with local wolf populations clearly occurred elsewhere in the early history of specific lineages. More recently, the evolution of modern dog breeds seems to have been an iterative process that drew on a limited genetic toolkit to create remarkable phenotypic diversity

    Preimplantation genetic testing for aneuploidy versus morphology as selection criteria for single frozen-thawed embryo transfer in good-prognosis patients: a multicenter randomized clinical trial

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    Adhesins, Receptors, and Target Substrata Involved in the Adhesion of Pathogenic Bacteria to Host Cells and Tissues

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