In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid

Includes bibliographical references.Drug metabolism is recognised as a key component of the drug discovery and development process. It exerts an influence on the action, duration of action and toxicity of a drug in vivo. The integration of drug metabolism studies is therefore crucial to compound progression through the various stages of the development process. This work details the in vitro metabolism work conducted during the early development of aminoquinoline tetrazoles, and derivatives of metergoline and fusidic acid as potential antiplasmodial and/or antimycobacterial agents

A rare variant branch from the lateral cord and a communicating branch between the musculocutaneous and median nerve

During routine educational gross anatomy dissections of the upper extremities, one right upper limb was observed to have an unusual branch from the  lateral cord that pierced coracobrachialis towards its origin. This variant branch emerged from the lateral cord before it branched to give its contribution  to the median nerve and musculocutaneous nerve in the axilla. The same limb also had a communicating branch between the musculocutaneous nerve  to the median nerve at the mid arm level. These variations may be of interest to neurologists, anatomists and surgeons operating in the upper limb  region

TRANSACTIONAL DISTANCE IN MIDDLE AND HIGH SCHOOL ONLINE LEARNING ENVIRONMENTS: AN EMPIRICAL STUDY

TRANSACTIONAL DISTANCE IN MIDDLE AND HIGH SCHOOL ONLINE LEARNING ENVIRONMENTS: AN EMPIRICAL STUD

How College Instructors Use Social Media for Instruction

The use of social media has increased tremendously in recent years with many sectors using it for the purpose of communicating, sharing ideas, gathering information and stating opinions. The use of social media has trickled down into education with instructors using it for teaching and learning. This study used Gagne\u27s Nine Events of Instruction as a framework to investigate the types of social media applications used, and how they are specifically used for instructional purpose in colleges. The study used both qualitative and quantitative methods to analyze data. Results indicated that about 31% of instructors use different social media types in diverse ways that related to Gagne\u27s Nine Events of Instructional design. The study gives insight on the ingenious ways in which instructors use social media for instruction

The Influence of Regulated Marital Conflict Resolution Styles on Marital Stability in Kiambu County, Kenya

The purpose of the study was to establish the relationship between regulated conflict resolution styles and marital stability in Kiambu County, Kenya. Specifically, the study sought to: establish the types of marital conflicts among married individuals in Kiambu County; determine the various marital conflict resolution styles used by married individuals in the County, and; establish the relationship between marital conflict resolution styles and marital stability. Descriptive-correlation research design was used. Data was collected from 96 married individuals aged 18 years and above by aid of a structured questionnaire. Data analysis was carried out using SPSS. The statistical techniques applied included independent samples T-test, Chisquare and Mann-Whitney U test. The results showed that most types of conflicts were solvable. Descriptive statistics indicated that regulated marital conflict resolution styles were used by majority of the respondents, with validating styles being the most applied (M=2.87, SD=0.745). This was followed by volatile styles (M=2.79, SD=0.827) and avoidant styles (M=2.79, SD=0.739). The difference between individuals in stable marriages and those in unstable marriages was not statistically significant in terms of their use of regulated marital conflict resolution styles. It was concluded that regulated conflict resolution styles were a necessary but not sufficient conditions for marital stability. It was recommended that premarital counselors should highlight to the would be couples that some conflicts are perpetual and therefore require coping with, rather than resolving

The British colonial policy in Kenya, 1900-1960

Thesis (M.S.)--Boston Universit

Comparative Analysis of Racist Implications of the Welfare State in the U.S. vs. U.K. through Child Benefits

This thesis explores America’s narratives surrounding safety net, varying history of child benefits and welfare between the U.S and U.K., newfound research regarding England’s programs, implicit bias, and interviews and scholarly reports of relevant experts. By comparing the welfare states of both the U.S and the U.K, it is proven how racism is both deeply rooted in how citizens of both countries perceive safety nets, and has thus led to the exclusion of racial minorities in both welfare systems. Specifically, looking at child benefits, we can determine these negative impacts and policies erected which further oppress Black Americans, the Black British, and other oppressed minorities. Finally, it explores the prospect of future solutions in an anti-racist welfare state, while also praising certain successful aspects of the British/European socialism welfare system

Demystifying Mathematics: handling learning difficulties in Mathematics among low achievers in Kenyan schools

Mathematics is a compulsory subject in both primary and secondary schools in Kenya. However, learners’ poor performance in the subject in Kenya national examinations year in year out remains a serious concern for teachers of Mathematics, parents, curriculum developers, and the general public. This is particularly worrying because of the importance attached to the subject in national development hence the need to find out what could be affecting learning of Mathematics in Kenyan schools. The research on which this paper is based sought to examine the factors that influence performance in Mathematics in Kenyan schools; identify the characteristics of Mathematics learning disabilities; determine how the learners with such learning disabilities can be assessed and identified and interventions for these difficulties implemented. A case study was undertaken on class six learners in a primary school in Nairobi County. The tools used for the research were: classroom observations and an Individualized Education Program (IEP) developed by the teachers with the help of the researcher. This paper therefore highlights the findings from the research, discusses the implications of the findings and suggests the way forward as far as teaching, learning and assessment of Mathematics in Kenyan schools is concerned. Perhaps with the application of the right interventions, poor performance in Mathematics in the national examinations in Kenya will be a thing of the past

Education as a tool for empowering Kenya's street children for integration in national development

Education is an empowering process that enables those who have been marginalized in the social, economic, political and cultural spheres to claim their status as fully participating members of the society. Nevertheless, about 300,000 street children in Kenya have had no formal education and are not proficient in the two languages used – English (official language) and Swahili (national language)- languages in which vital information leading to improved livelihoods and participation in national development is available. Drawing evidence from an ongoing study on the literacy and numeracy needs of street children in Kenya, I argue that street children need to be equipped with appropriate knowledge through acquisition of numeracy, language and literacy skills for them to be fully empowered to be able to participate in the country's development. Journal of Language, Technology & Entrepreneurship in Africa Vol. 1 (2) 2009: pp. 244-25