9,633 research outputs found
A eubacterial origin for the human tRNA nucleotidyltransferase?
tRNA CCA-termini are generated and maintained by tRNA nucleotidyltransferases. Together with poly(A) polymerases and other enzymes they belong to the nucleotidyltransferase superfamily. However, sequence alignments within this family do not allow to distinguish between CCA-adding enzymes and poly(A) polymerases. Furthermore, due to the lack of sequence information about animal CCA-adding enzymes, identification of corresponding animal genes was not possible so far. Therefore, we looked for the human homolog using the baker's yeast tRNA nucleotidyltransferase as a query sequence in a BLAST search. This revealed that the human gene transcript CGI-47, (\#AF151805) deposited in GenBank is likely to encode such an enzyme. To identify the nature of this protein, the cDNA of the transcript was cloned and the recombinant protein biochemically characterized, indicating that CGI-47 encodes a bona fide CCA-adding enzyme and not a poly(A) polymerase. This confirmed animal CCA-adding enzyme allowed us to identify putative homologs from other animals. Calculation of a neighbor-joining tree, using an alignment of several CCA-adding enzymes, revealed that the animal enzymes resemble more eubacterial ones than eukaryotic plant and fungal tRNA nucleotidyltransferases, suggesting that the animal nuclear cca genes might have been derived from the endosymbiotic progenitor of mitochondria and are therefore of eubacterial origin
A spatial interpretation of emerging superconductivity in lightly doped cuprates
The formation of domains comprising alternating 'hole rich' and 'hole poor'
ladders recently observed by Scanning Tunneling Microscopy by Kohsaka et al.,
on lightly hole doped cuprates, is interpreted in terms of an attractive
mechanism which favors the presence of doped holes on Cu sites located each on
one side of an oxygen atom. This mechanism leads to a geometrical pattern of
alternating hole-rich and hole-poor ladders with a periodicity equal to 4 times
the lattice spacing in the CuO plane, as observed experimentally. To cite this
article: G. Deutscher, P.-G. de Gennes, C. R. Physique 8 (2007).Comment: 4 pages, 3 figuer
Field Induced Nodal Order Parameter in the Tunneling Spectrum of YBaCuO Superconductor
We report planar tunneling measurements on thin films of
YBaCuO at various doping levels under magnetic fields. By
choosing a special setup configuration, we have probed a field induced energy
scale that dominates in the vicinity of a node of the d-wave superconducting
order parameter. We found a high doping sensitivity for this energy scale. At
Optimum doping this energy scale is in agreement with an induced
order parameter. We found that it can be followed down to low fields at optimum
doping, but not away from it.Comment: 9 pages, 8 figures, accepted for publication in Phys. Rev.
Proximity effect in granular superconductor-normal metal structures
We fabricated three-dimensional disordered Pb-Cu granular structures, with
various metal compositions. The typical grain size of both metals is smaller
than the superconductor and normal metal coherence lengths, thus satisfying the
Cooper limit. The critical temperature of the samples was measured and compared
with the critical temperature of bilayers. We show how the proximity effect
theories, developed for bilayers, can be modified for random mixtures and we
demonstrate that our experimental data fit well the de Gennes weak coupling
limit theory in the Cooper limit. Our results indicate that, in granular
structures, the Cooper limit can be satisfied over a wide range of
concentrations.Comment: 15 pages, 4 figure
Quantum Effects and Broken Symmetries in Frustrated Antiferromagnets
We investigate the interplay between frustration and zero-point quantum
fluctuations in the ground state of the triangular and Heisenberg
antiferromagnets, using finite-size spin-wave theory, exact diagonalization,
and quantum Monte Carlo methods. In the triangular Heisenberg antiferromagnet,
by performing a systematic size-scaling analysis, we have obtained strong
evidences for a gapless spectrum and a finite value of the thermodynamic order
parameter, thus confirming the existence of long-range N\'eel order.The good
agreement between the finite-size spin-wave results and the exact and quantum
Monte Carlo data also supports the reliability of the spin-wave expansion to
describe both the ground state and the low-energy spin excitations of the
triangular Heisenberg antiferromagnet. In the Heisenberg model, our
results indicate the opening of a finite gap in the thermodynamic excitation
spectrum at , marking the melting of the antiferromagnetic
N\'eel order and the onset of a non-magnetic ground state. In order to
characterize the nature of the latter quantum-disordered phase we have computed
the susceptibilities for the most important crystal symmetry breaking
operators. In the ordered phase the effectiveness of the spin-wave theory in
reproducing the low-energy excitation spectrum suggests that the uniform spin
susceptibility of the model is very close to the linear spin-wave prediction.Comment: Review article, 44 pages, 18 figures. See also PRL 87, 097201 (2001
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