A 6-bit 2GS/s CMOS Time-Interleaved ADC for Analysis of Mixed-Signal Calibration Techniques

A 6-bit 2-GS/s time interleaved (TI) successive approximation register (SAR) analog-to-digital converter (ADC) is designed and fabricated in a 0.13 μm CMOS process. The architecture uses 8 time-interleaved track-and-hold amplifiers (THA), and 16 SARADC’s. Thechipincludes (i) a programmable delay cell array to adjust the interleaved sampling phase, and (ii) a 12 Gbps low voltage differential signaling (LVDS) interface. These blocks make the fabricated ADC an excellent platform to evaluate mixed-signal calibration techniques, which are of great interest for application in high-speed optical systems. Measurements of the fabricated ADC show 33.9 dB of peak signal-to-noise-and-distortion ratio (SNDR) and 192 mW of power consumption at 1.2 Vhttp://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=6820267Fil: Reyes, Benjamín. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.Fil: Tealdi, Lucas. Fundación Fulgor; Argentina.Fil: Paulina, German. Fundación Fulgor; Argentina.Fil: Labat, Emanuel. Fundación Fulgor; Argentina.Fil: Sánchez, Raúl. Fundación Fulgor; Argentina.Fil: Mandolesi, Pablo. Universidad Nacional del Sur. Grupo de Investigación en Sistemas Electrónicos y Electromecatrónicos (GISEE). Laboratorio de Micro y Nano Electrónica (LMNE); Argentina.Fil: Hueda, Mario. Universidad Nacional de Córdoba. Consejo Nacional de Investigaciones Científicas y Técnicas. Laboratorio de Comunicaciones Digitales; Argentina.Fil: Reyes, Benjamín. Consejo Nacional de Investigaciones Científicas y Técnicas. Laboratorio de Comunicaciones Digitales; Argentina.Telecomunicacione

A 1.6Gb/s CMOS LVDS Transmitter with a Programmable Pre-Emphasis System

A 12 parallel low voltage differential signaling (LVDS) transmitter fabricated in 0.13 μm CMOS is presented. Each LVDS channel can operate over 1.6 Gb/s and includes a programmable pre-emphasis circuit designed to reduce the data-dependent jitter (DDJ) caused by different lengths of PCB traces. Experimental results of the fabricated LVDS confirm the correct operation of the programmable pre-equalization circuit. The power consumption and area per channel is less than 20 mW and 0.084 mm2, respectively.http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=6820268Fil: Reyes, Benjamín T. Universidad Nacional de Córdoba. Consejo Nacional de Investigaciones Científicas y Técnicas. Laboratorio de Comunicaciones Digitales; Argentina.Fil: Paulina, German. Fundación Fulgor; Argentina.Fil: Tealdi, Lucas. Fundación Fulgor; Argentina.Fil: Labat, Emanuel. Fundación Fulgor; Argentina.Fil: Sanchez, Raúl. Fundación Fulgor; Argentina.Fil: Mandolesi, Pablo S. Universidad Nacional del Sur. GISEE – LMNE; Argentina.Fil: Hueda, Mario R. Universidad Nacional de Córdoba. Consejo Nacional de Investigaciones Científicas y Técnicas. Laboratorio de Comunicaciones Digitales; Argentina.Telecomunicacione

The impact of latent heat exchanges on the design of earth air heat exchangers

WOS:000419407500030International audienceThe work documents the design of Earth-Air Heat Exchangers based not only on sensible heat transfer, but also on latent heat exchanges. We compare the impact of the climate of Brazil and south of France on the relevance of such systems. The duct length is determined in order to obtain maximum underground heat exchanges. A time dependent model combined to actual weather data is developed to show when an underground heat exchanger becomes a good option in a tropical climate. The three-dimensional version of the model accounts for heat transfer in the soil and for heat and moisture transfer along the underground pipe. The comparison with a 1D model allows to propose a straightforward approach to assess the cooling/heating potential of different climatic regions. (C) 2017 Elsevier Ltd. All rights reserved

A 1.6Gb/s CMOS LVDS transmitter with a programmable pre-emphasis system

A 12 parallel low voltage differential signaling (LVDS) transmitter fabricated in 0.13 μm CMOS is presented. Each LVDS channel can operate over 1.6 Gb/s and includes a programmable pre-emphasis circuit designed to reduce the data-dependent jitter (DDJ) caused by different lengths of PCB traces. Experimental results of the fabricated LVDS confirm the correct operation of the programmable pre-equalization circuit. The power consumption and area per channel is less than 20 mW and 0.084 mm2, respectively.http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=6820268Fil: Reyes, Benjamín T. Universidad Nacional de Córdoba. Consejo Nacional de Investigaciones Científicas y Técnicas. Laboratorio de Comunicaciones Digitales; Argentina.Fil: Paulina, German. Fundación Fulgor; Argentina.Fil: Tealdi, Lucas. Fundación Fulgor; Argentina.Fil: Labat, Emanuel. Fundación Fulgor; Argentina.Fil: Sanchez, Raúl. Fundación Fulgor; Argentina.Fil: Mandolesi, Pablo S. Universidad Nacional del Sur. GISEE – LMNE; Argentina.Fil: Hueda, Mario R. Universidad Nacional de Córdoba. Consejo Nacional de Investigaciones Científicas y Técnicas. Laboratorio de Comunicaciones Digitales; Argentina.Telecomunicacione

Drug Saf

Introduction After a safety warning was issued for a risk of muscular injury associated with dipeptidyl peptidase-4 (DPP-4) inhibitor use, especially when co-prescribed with statins, spontaneous reporting analyses provided conflicting results. Objective The aim of this study was to investigate the association between DPP-4 inhibitor use and the risk of muscular injury in individuals with type 2 diabetes mellitus using statins or fibrates. Methods We conducted a nested case-control study amongst a cohort of individuals with type 2 diabetes using statins or fibrates, identified from a nationwide French health insurance database (2009–2014). Cases of serious muscular injury were defined as subjects hospitalized for rhabdomyolysis or myopathy, or for whom testing for myoglobin or creatine phosphokinase followed by a change in statin or fibrate prescription (dose decrease, treatment switch, or stop) was identified. Up to ten controls were matched to each case according to sex, age, and type of lipid-lowering agent. Associations between DPP-4 inhibitor use and serious muscular injury were estimated using a multivariate conditional logistic regression model, providing odds ratios (ORs) adjusted for alcoholism, chronic renal failure, hypothyroidism, and number of concomitant drugs. Results Within the 35,117 individuals with type 2 diabetes mellitus constituting the source cohort, 437 statin-user cases were identified who were matched to 4358 statin-user controls. Similarly, 54 fibrate-user cases were identified who were matched to 540 fibrate-user controls. The adjusted OR for DPP-4 inhibitor use and serious muscular injury was estimated at 1.0 (95% confidence interval [CI] 0.7–1.2) in statin users and 0.8 (95% CI 0.4–1.9) in fibrate users. Conclusion In this study, DPP-4 inhibitor use was not associated with an increased risk of serious muscular injury among patients with type 2 diabetes mellitus using statins or fibrates

Testing DRAINMOD-FOREST for predicting evapotranspiration in a mid-rotation pine plantation

Evapotranspiration (ET) is a key component of the hydrologic cycle in terrestrial ecosystems and accurate description of ET processes is essential for developing reliable ecohydrological models. This study investigated the accuracy of ET prediction by the DRAINMOD-FOREST after its calibration/validation for predicting commonly measured hydrological variables. The model was tested by conducting an eight year simulation of drainage and shallow groundwater dynamics in a managed mid-rotation loblolly pine (Pinus taeda L.) plantation located in the coastal plain of North Carolina, USA. Modeled daily ET rates were compared to those measured in the field using the eddy covariance technique. In addition, the wavelet transform and coherence analysis were used to compare ET predictions and measurements on the time-frequency domain. Results showed that DRAINMOD-FOREST accurately predicted annual and monthly ET after a successful calibration and validation using measured drainage rates and water table depth. The model under predicted ET on an annual basis by 2%, while the Nash-Sutcliffe coefficient of model predictions on a monthly basis was 0.78. Results from wavelet transform and coherence analysis demonstrated that the model reasonably captured the high power spectra of ET at an annual scale with significantly high model-data coherency. These results suggested that the calibrated DRAINMOD-FOREST collectively captured key factors and mechanisms controlling ET dynamics in the drained pine plantation. However, the global power spectrum revealed that the model over predicted the power spectrum of Er at an annual scale, suggesting the model may have under predicted canopy conductance during non-growing seasons. In addition, this study also suggested that DRAINMOD-FOREST did not properly capture the seasonal dynamics of ET under extreme drought conditions with deeper water table depths. These results suggested further refinement to parameters, particularly vegetation related, and structures of DRAINMOD-FOREST to achieve better agreement between ET predictions and measurements in the time-frequency domain