Critical Insights: The Hobbit (2016) edited by Stephen W. Potts

Book review by Martin Simonson of Critical Insights: The Hobbit (2016), edited by Stephen W. Pott

Flora of Middle-earth (2017) by Walter S. Judd and Graham A. Judd

Book review by Martin Simonson of Flora of Middle-earth (2017) by Walter S. Judd and Graham A. Jud

Radical Joy Performed into Action: A Study of Feminist Performance Art

Although traditionally excluded from the art world as from all major institutions, women artists staked their claim by revolutionizing performance art as a medium in the 1960s and 70s. By integrating life and art, feminist artists developed the powerful ideology that “the personal is political,” especially in art. From this foundation of radical assertion, feminist artists explored, resisted, and deconstructed their struggles. Contemporary feminist artists not only have different battles to fight, they fight them in a different format: digital media. In this project, I seek to explore the ways performance artists before me have used the medium of performance art for radical change, and the ways it can be used to affect change in the future

Snapshot: Emergency Department Visits for Preventable Dental Conditions in California

Provides an overview of dental health in California, the supply of providers, and out-of-pocket expenses. Presents data on emergency room visits for preventable conditions, by condition, county, age, gender, race/ethnicity, and insurance status and type

Reduction of fan noise: A concept

Acoustic materials strategically located within or near noise sources are effective for noise abatement on wing mounted lift fans, nozzles, engines and other noise sources. Panels are straightforward and easily adaptable to situations outside of aircraft technology

Geological evidence for a 2.6-Ga strewn field of impact spherules in the Hamersley Basin of Western Australia

Sand-sized spherules up to 1.7 mm across with spherulitic, vesicular, and other crystalline textures that consist mainly of K-feldspar help define a unique horizon in the well-preserved 2.6-Ga Wittenoom Formation in the Hamersley Basin of Western Australia. This layer is informally known as the spherule marker bed. In the northeastern part of the Hamersley Basin, similar spherules again occur at only one horizon, but here they are a minor constituent of a dolomitic debris-flow deposit known as the dolomixtite layer. The dolomixtite layer occurs in the Carawine Dolomite, which is stratigraphically equivalent to the Wittenoom Formation. Moreover, paleocurrent data from closely associated carbonate and volcaniclastic turbidites indicate the spherule marker bed was deposited in deeper-water paleoenvironments than the dolomixtite layer. Therefore, the dolomixtite layer is believed to be a proximal equivalent of the spherule marker bed. The layers that host the spherules are interpreted to be the deposits of a major sediment gravity flow that exhumed and redeposited most of the spherules after shallow burial, although the flow is not believed to have been a direct result of the proposed impact. The most likely site for the proposed impact would have been in the early Precambrian ocean close to the northeastern edge of the Pilbara Craton. Another thin horizon in the overlying Brockman Iron Formation contains spherules that again consist largely of K-feldspar and have internal textures strikingly similar to those of the Wittenoom Formation and Carawine Dolomite. The close resemblance of these spherules to those of the Wittenoom Formation and Carawine Dolomite suggests they also originated as impact melt droplets, even though they are admixed with volcaniclastic detritus. The stratigraphic separation between the two suggests that a second major impact occurred near the Hamersley Basin after a time interval of about 75 m.y. elapsed. This suggests the record of impacts in early Precambrian strata is richer than is generally appreciated

Saturated free fatty acids and apoptosis in microvascular mesangial cells: palmitate activates pro-apoptotic signaling involving caspase 9 and mitochondrial release of endonuclease G

BACKGROUND: In type 2 diabetes, free fatty acids (FFA) accumulate in microvascular cells, but the phenotypic consequences of FFA accumulation in the microvasculature are incompletely understood. Here we investigated whether saturated FFA induce apoptosis in human microvascular mesangial cells and analyzed the signaling pathways involved. METHODS: Saturated and unsaturated FFA-albumin complexes were added to cultured human mesangial cells, after which the number of apoptotic cells were quantified and the signal transduction pathways involved were delineated. RESULTS: The saturated FFA palmitate and stearate were apoptotic unlike equivalent concentrations of the unsaturated FFA oleate and linoleate. Palmitate-induced apoptosis was potentiated by etomoxir, an inhibitor of mitochondrial β-oxidation, but was prevented by an activator of AMP-kinase, which increases fatty acid β-oxidation. Palmitate stimulated an intrinsic pathway of pro-apoptotic signaling as evidenced by increased mitochondrial release of cytochrome-c and activation of caspase 9. A caspase 9-selective inhibitor blocked caspase 3 activation but incompletely blocked apoptosis in response to palmitate, suggesting an additional caspase 9-independent pathway. Palmitate stimulated mitochondrial release of endonuclease G by a caspase 9-independent mechanism, thereby implicating endonuclease G in caspase 9-indpendent regulation of apoptosis by saturated FFA. We also observed that the unsaturated FFA oleate and linoleate prevented palmitate-induced mitochondrial release of both cytochrome-c and endonuclease G, which resulted in complete protection from palmitate-induced apoptosis. CONCLUSIONS: Taken together, these results demonstrate that palmitate stimulates apoptosis by evoking an intrinsic pathway of proapoptotic signaling and identify mitochondrial release of endonuclease G as a key step in proapoptotic signaling by saturated FFA and in the anti-apoptotic actions of unsaturated FFA

Comparative evaluation of ERTS-A imagery for resource inventory in land-use planning

There are no author-identified significant results in this report. The overall objectives of this program are: (1) use of multidiscipline team approach to determine features that can be successfully monitored by ERTS-1 imagery for resource inventory, planning, land use zoning, and resource development; and (2) using carefully selected sample areas, develop a comprehensive resource inventory mapping system for use in planning, zoning, and resource development. Progress has included compilation and organization of ground truth data and observations in the primary study area of Crook County; resource inventory legend development; assembly and testing of color enhancement equipment; development and adaption of programs for digital data processing; and quick-look evaluations of initial ERTS-1 imagery for Oregon