31,823 research outputs found

    'The good paper – a handbook for writing papers in higher education' by Lotte Rienecker, Peter Stray Jorgensen, with contributions by Signe Skov : review

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    Book review'The good paper – a handbook for writing papers in higher education' by Lotte Rienecker, Peter Stray Jorgensen, with contributions by Signe Skov. Samsfundslitteratur

    A Survey of California Nurse Practitioners\u27 Health Practices and Counseling Habits

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    Morbidity and mortality due to obesity continues to rise in the United States despite well known Healthy People 2010 and American College of Sports Medicine guidelines on physical activity. In the U.S. today, more than 60 percent of Americans aged 20 years and older are overweight (Hedley et al., 2004). This study investigated the exercise practices of California nurse practitioners (NPs }, how their practices compare to recommended guidelines, and to what extent California NPs prescribe aerobic exercise and strength training to their clients. The California Nurse Practitioners Physical Activity Questionnaire was self-administered at the annual2005 California Association for Nurse Practitioners (CANP) conference. The number of participants was 130 California NPs. The study tool assessed five areas. The results show although most NPs do participate in moderate (50.8%) aerobic activity at least 3-5 days a week (53.8%) and strength training at least 1-2 days a week (30.8%), only 16.2% ofNPs devote 6-7 days a week to aerobic exercise. The information gathered from the research study can be utilized to implement further interventions targeting the obesity problem, which will contribute a more positive outcome for the overall population

    Think Before You Click: An Analysis of Facebook as a Source of News

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    The purpose of this study is to analyze how millennial college students perceive and interpret the news-related content that is posted on the social networking website Facebook. The news that this study is focused on is related to major events in American politics, especially this past Presidential election. One research question was developed to compete this study: what influence are news stories being shared on Facebook having on millennials? In order to determine the answer to this question, focus groups with college students at Bryant University were held in which the students were asked to evaluate a news article and give their thoughts and opinions on current American events and how they are portrayed on social media

    Role of small colony variants in persistence of Pseudomonas aeruginosa infections in cystic fibrosis lungs

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    Jacob G Malone1,21John Innes Centre, Norwich, UK; 2School of Biological Sciences, University of East Anglia, Norwich, UKAbstract: Pseudomonas aeruginosa is an opportunistic pathogen that predominates during the later stages of cystic fibrosis (CF) lung infections. Over many years of chronic lung colonization, P. aeruginosa undergoes extensive adaptation to the lung environment, evolving both toward a persistent, low virulence state and simultaneously diversifying to produce a number of phenotypically distinct morphs. These lung-adapted P. aeruginosa strains include the small colony variants (SCVs), small, autoaggregative isolates that show enhanced biofilm formation, strong attachment to surfaces, and increased production of exopolysaccharides. Their appearance in the sputum of CF patients correlates with increased resistance to antibiotics, poor lung function, and prolonged persistence of infection, increasing their relevance as a subject for clinical investigation. The evolution of SCVs in the CF lung is associated with overproduction of the ubiquitous bacterial signaling molecule cyclic-di-GMP, with increased cyclic-di-GMP levels shown to be responsible for the SCV phenotype in a number of different CF lung isolates. Here, we review the current state of research in clinical P. aeruginosa SCVs. We will discuss the phenotypic characteristics underpinning the SCV morphotype, the clinical implications of lung colonization with SCVs, and the molecular basis and clinical evolution of the SCV phenotype in the CF lung environment.Keywords: small colony variants, cystic fibrosis, cyclic-di-GMP, Pseudomonas aeruginosa, RsmA, antibiotic

    Isometries of Products of Path-Connected Locally Uniquely Geodesic Metric Spaces with the Sup Metric are Reducible

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    Let MiM_i and NiN_i be path-connected locally uniquely geodesic metric spaces that are not points and f:∏i=1mMi→∏i=1nNif:\prod_{i=1}^m M_i\to \prod_{i=1}^n N_i be an isometry where ∏i=1nNi\prod_{i=1}^n N_i and ∏i=1mMi\prod_{i=1}^m M_i are given the sup metric. Then m=nm=n and after reindexing MiM_i is isometric to NiN_i for all ii. Moreover ff is a composition of an isometry that reindexes the factor spaces and an isometry that is a product of isometries fi:Mi→Nif_i:M_i\to N_i.Comment: 7 pages, 1 figur

    The effects of ageing and exercise on skeletal muscle structure and function

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    Musculoskeletal ageing is associated with profound morphological and functional changes that increase fall risk and disease incidence and is characterised by age-related reductions in motor unit number and atrophy of muscle fibres, particularly type II fibres. Decrements in functional strength and power are relatively modest until the 6th decade, after which the rate of loss exponentially accelerates, particularly beyond the 8th decade of life. Physical activity is a therapeutic modality that can significantly attenuate age-related decline. The underlying signature of ageing, as manifested by perturbed redox homeostasis, leads to a blunting of acute and chronic redox regulated exercise adaptations. Impaired redox regulated exercise adaptations are mechanistically related to altered exercise-induced reactive oxygen and nitrogen species generation and a resultant failure to properly activate redox regulated signaling cascades. Despite the aforementioned specific impairment in redox signaling, exercise induces a plethora of beneficial effects, irrespective of age. There is, therefore, strong evidence for promoting regular physical exercise, especially progressive resistance training as a lifelong habitual practice

    Walking Together: Living Fearlessly, Loving Boldy

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    In this paper, I give an account of my capstone for the Religious Studies major. I tell about the research project-turned-applied-learning, and how my research as a Mellon Summer Scholar ’15 led me to start a prison ministry between Gettysburg students and the Adams County Adult Correctional Complex. I reflect on what I have done, how God has worked, and what I have learned. This is far from a typical research paper; then again, this was far from a typical research project

    The United States and the Law of the Sea After UNCLOS III

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    The Death Knell For the Death Penalty and the Significance of Global Realism to its Abolition from Glossip v. Gross to Brumfield v. Cain

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    The Supreme Court’s jurisprudence regarding the death penalty, whether or not cruel, has most certainly been unusual in the annals of criminal punishment. In the short span of four years, the Court foreclosed and then reopened this form of punishment in Furman v. Georgia and Gregg v. Georgia. One year later the Court would categorically exclude the punishment for the rape of an adult. Five years later the Court would again preclude the punishment, for any defendant convicted of felony-murder who did not participate or share in the homicidal act or intent. In 1986 the Court would struggle with the Orwellian issue of whether and how a person must be competent to be executed in Ford v. Wainwright. In 1989, in two cases decided on the same day, the Court refused to find that the “mentally retarded” or juveniles were categorically exempt from the death penalty, in opinions that both embodied the “national consensus” test for death penalty restrictions and questioned its exclusivity as the determinate measure of cruel and unusual punishment. In the decade that followed, the ground began to shift under the Court’s jurisprudence in a number of ways. Coalitions opposed to the death penalty in specific instances and in general expanded to encompass international human rights advocates dedicated as amicus curiae or pro bono counsel to highlight the United States’ growing isolation in its official acceptance of the punishment. In 2002, the landmark case of Atkins v. Virginia would invigorate categorical exclusions from the death penalty, recognizing that the “mentally retarded” could not be subject to the harshest form of punishment. Roper v. Simmons would add juvenile offenders to the categorical exclusions. In 2008, rape of a child where the crime did not result, and was not intended to result, in the victim’s death, was added as an offense which did not qualify for the death penalty. In a span of four years, the Court would expand protection of juvenile offenders from life without parole, first for non-homicidal offenses, then for any offense. In addition, the Court found itself mired after Furman in what one commentator has described as “an unparalleled level of constitutional micromanagement” as to how the death penalty can be imposed procedurally and when it can be imposed based on the nature of the offense and the status of the offender. For the October 2015 term, the Court granted certiorari in a consolidated trio of cases and an additional case raising such procedural issues. The Montgomery v. Louisiana decision on January 25, 2016 applied the prohibition on life without parole for juvenile offenders retroactively, releasing prisoners who had spent their entire “adult” lives behind bars. Against this backdrop, the Court’s 2015 decision in Glossip v. Gross is a notable victory, as it were, for the death penalty. In the almost inevitable 5-4 split, the Court refused to find that the specific method of execution, a three-drug protocol begun with midazolam, constituted cruel and unusual punishment. The decision is at best a Pyrrhic victory for the death penalty, however, given the specificity of the method in question. More importantly, the majority opinion was largely eclipsed by Justice Breyer’s dissent, joined by Justice Ginsburg, which called for total abolition of the death penalty. This article also seeks to demonstrate that the opinion exemplifies the need for what might be termed “global realism” in recognizing that consideration of international legal norms and political realities is unavoidable in the Supreme Court’s jurisprudence. The method of execution itself was the unavoidable result of a refusal of drug suppliers outside the U.S. to continue supplying drugs for execution purposes, and Justice Breyer’s dissent brought to the forefront once again the isolation of the United States’ acceptance of the death penalty. Glossip v. Gross, thus, may be the beginning of the end of the death penalty due to a confluence of a shift in constitutional legal analysis from the “national consensus” analysis to proportionality and penological purposes served, empirical evidence that there is no national consensus in favor of the death penalty, a renewed recognition of the unreliability of decision-making whatever procedural prerequisites the Court imposes, and an overdue, forthright recognition of the significance of international norms and practices in determining “evolving standards of decency” under the Eighth Amendment. This recognition is explicit in Justice Breyer’s dissent, but also fundamental to evaluating what Justice Kennedy’s position might be on abolishing the death penalty, notwithstanding his joining the five justices in Glossip v. Gross
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