Acute panuveitis with hypopyon in Crohn's disease secondary to medical therapy: a case report

<p>Abstract</p> <p>Background</p> <p>A case report to highlight the association between rifabutin and hypopyon</p> <p>Methods</p> <p>A 56 year old male presented with a one day history of blurred vision in his right eye. He had an established diagnosis of Crohn's disease which was in remission following treatment with rifabutin and clarithromycin. A brisk anterior uveitis with hypopyon and a mild vitritis was detected in the right eye. The acute inflammatory episode resolved following treatment with topical corticosteroids and withdrawal of rifabutin.</p> <p>Results</p> <p>The presence of hypopyon is atypical in uveitis associated with inflammatory bowel disease. The association between rifabutin treatment and hypopyon uveitis is well recognised in Mycobacterium avium paratuberculosis. However, use of rifabutin in the management of Crohn's disease is controversial and not widely known to an ophthalmic readership.</p> <p>Conclusion</p> <p>This report highlights the importance of keeping abreast of novel therapeutic developments in systemic conditions likely to be encountered in ophthalmology.</p

Case report: Undetected retained orbital wood fragment mimicking orbital cellulitis

Wooden foreign bodies (FBs) within the orbit are difficult to diagnose both clinically and radiologically [1]. In acute settings, wood can be missed on standard computerized tomography (CT) due to its hypodense appearance which can be mistaken for air. If left undetected, wood fragments impose a significant risk of infection [2]. Therefore, its prompt removal, particularly from the head and neck region, is essential.Our case describes a 31-year-old man who presented with a clinical picture of orbital cellulitis post trauma, who was later found to have a large retained fragment of wood, initially undetected on CT orbits