Shelter Development Through Cooperatives: A Strategy for Poverty Alleviation and Slum Improvement for Asia and the Pacific Region

The research traces the flow of humanity from the urban areas to the cities thus creating severe economic and social problems in the cities thus leading to homelessness; lack of sanitation; health hazards; crimes; vandalism; drugs; children wandering around and a host of problems which civic society leaders are not willing or able to act upon because slums are also vote banks for politicians

Commutators and Anti-Commutators of Idempotents in Rings

We show that a ring $\,R\,$ has two idempotents $\,e,e'\,$ with an invertible commutator $\,ee'-e'e\,$ if and only if $\,R \cong {\mathbb M}_2(S)\,$ for a ring $\,S\,$ in which $\,1\,$ is a sum of two units. In this case, the "anti-commutator" $\,ee'+e'e\,$ is automatically invertible, so we study also the broader class of rings having such an invertible anti-commutator. Simple artinian rings $\,R\,$ (along with other related classes of matrix rings) with one of the above properties are completely determined. In this study, we also arrive at various new criteria for {\it general\} $\,2\times 2\,$ matrix rings. For instance, $R\,$ is such a matrix ring if and only if it has an invertible commutator $\,er-re\,$ where $\,e^2=e$.Comment: 21 page

Targeting crosstalk between Nrf-2, NF-κB and androgen receptor signaling in prostate cancer

Oxidative stress, inflammation and androgen receptor (AR) signaling play a pivotal role in the initiation, development and progression of prostate cancer (PCa). Numerous papers in the literature have documented the interconnection between oxidative stress and inflammation; and how antioxidants can combat the inflammation. It has been shown in the literature that both oxidative stress and inflammation regulate AR, the key receptor involved in the transition of PCa to castration resistant prostate cancer (CRPC). In this review, we discuss about the importance of targeting Nrf-2-antioxidant signaling, NF-κB inflammatory response and AR signaling in PCa. Finally, we discuss about the crosstalk between these three critical pathways as well as how the anti-inflammatory antioxidant phytochemicals like sulforaphane (SFN) and curcumin (CUR), which can also target AR, can be ideal candidates in the chemoprevention of PCa