279 research outputs found
Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abbott DC
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
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- Stewart GA
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- Strandberg J
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- Strauss M
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- Sulin VV
- Sullivan MJ
- Sultan DMS
- Sultansoy S
- Sumida T
- Sun S
- Sun X
- Suruliz K
- Suster CJE
- Sutton MR
- Suzuki S
- Svatos M
- Swiatlowski M
- Swift SP
- Swirski T
- Sydorenko A
- Sykora I
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- Sykora T
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- Tamir NM
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- Tariq K
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- Tartarelli GF
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- Teoh JJ
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- Terashi K
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- Teuscher RJ
- Thais SJ
- Theveneaux-Pelzer T
- Thiele F
- Thomas DW
- Thomas JO
- Thomas JP
- Thompson PD
- Thomsen LA
- Thomson E
- Thorpe EJ
- Tikhomirov VO
- Tikhonov YA
- Timoshenko S
- Tipton P
- Tisserant S
- Tobon CAM
- Todome K
- Todorova-Nova S
- Todt S
- Tojo J
- Tokar S
- Tokushuku K
- Tolley E
- Tomiwa KG
- Tomoto M
- Tompkins L
- Tong B
- Tornambe P
- Toro RC
- Torrence E
- Torres H
- Torres RET
- Tosciri C
- Toth J
- Tovey DR
- Traeet A
- Treado CJ
- Trefzger T
- Tresoldi F
- Tricoli A
- Trigger IM
- Trincaz-Duvoid S
- Trischuk DA
- Trischuk W
- Trocme B
- Trofymov A
- Troncon C
- Trovato F
- Truong L
- Trzebinski M
- Trzupek A
- Tsai F
- Tseng JC-L
- Tsiareshka P
- Tsirigotis A
- Tsiskaridze V
- Tskhadadze EG
- Tsopoulou M
- Tsukerman II
- Tsulaia V
- Tsuno S
- Tsybychev D
- Tu Y
- Tudorache A
- Tudorache V
- Tulbure TT
- Tuna AN
- Turchikhin S
- Turgeman D
- Turner RJ
- Turra RT
- Tuts PM
- Tzamarias S
- Tzovara E
- Ucchielli G
- Uchida K
- Ukegawa F
- Unal G
- Undrus A
- Unel G
- Ungaro FC
- Unno Y
- Uno K
- Urban J
- Urquijo P
- Usai G
- Uysal Z
- Vacek V
- Vachon B
- Vadla KOH
- Vaidya A
- Valderanis C
- Vale MAB
- Valente M
- Valentinetti S
- Valero A
- Valery L
- Vallance RA
- Vallier A
- Van Daalen TR
- Van Gemmeren P
- Van Vulpen I
- Vanadia M
- Vandelli W
- Vandenbroucke M
- Vandewall ER
- Vaniachine A
- Vannicola D
- Vari R
- Varnes EW
- Varni C
- Varol T
- Varouchas D
- Varvell KE
- Vasile ME
- Vasquez GA
- Vazeille F
- Vazquez Furelos D
- Vazquez CJB
- Vazquez JGP
- Veatch J
- Vecchio V
- Veen MJ
- Veloce LM
- Veloso F
- Veneziano S
- Ventura A
- Venturi N
- Vera AMR
- Verbytskyi A
- Vercesi V
- Verducci M
- Vergara JCR
- Vergis C
- Verkerke W
- Vermeulen AT
- Vermeulen JC
- Verzini MJA
- Vetterli MC
- Viaux Maira N
- Vickey T
- Viehhauser GHA
- Vigani L
- Villa M
- Vilucchi E
- Vincter MG
- Virdee GS
- Vishwakarma A
- Vittori C
- Vivarelli I
- Vogel M
- Vokac P
- von Buddenbrock SE
- Von Toerne E
- Vorobel V
- Vorobev K
- Vos M
- Vossebeld JH
- Vozak M
- Vranjes N
- Vrba V
- Vreeswijk M
- Vuillermet R
- Vukotic I
- Wagner P
- Wagner W
- Wagner-Kuhr J
- Wahdan S
- Wahlberg H
- Walbrecht VM
- Walder J
- Walker R
- Walker SD
- Walkowiak W
- Wallangen V
- Wang AM
- Wang AZ
- Wang C
- Wang F
- Wang H
- Wang J
- Wang P
- Wang Q
- Wang R
- Wang R-J
- Wang SM
- Wang W
- Wang WT
- Wang WX
- Wang Y
- Wang Z
- Wanotayaroj C
- Warburton A
- Ward CP
- Wardrope DR
- Warrack N
- Washbrook A
- Watson AT
- Watson MF
- Watts G
- Waugh BM
- Webb AF
- Webb S
- Weber C
- Weber MS
- Weber SA
- Weber SM
- Weidberg AR
- Weingarten J
- Weirich M
- Weiser C
- Wells PS
- Wenaus T
- Wengler T
- Wenig S
- Wermes N
- Werner MD
- Wessels M
- Weston TD
- Whalen K
- Whallon NL
- Wharton AM
- White A
- White AS
- White MJ
- Whiteson D
- Whitmore BW
- Wiedenmann W
- Wiel C
- Wielers M
- Wieseotte N
- Wiglesworth C
- Wiik-Fuchs LAM
- Wilkens HG
- Wilkins LJ
- Williams HH
- Williams S
- Willis C
- Willocq S
- Wingerter-Seez I
- Winkels E
- Winklmeier F
- Winston OJ
- Winter BT
- Wittgen M
- Wobisch M
- Wolf A
- Wolf TMH
- Wolff R
- Wolker R
- Wollrath J
- Wolter MW
- Wolters H
- Wong VWS
- Woods NL
- Worm SD
- Wosiek BK
- Wozniak KW
- Wraight K
- Wu SL
- Wu X
- Wu Y
- Wyatt TR
- Wynne BM
- Xella S
- Xi Z
- Xia L
- Xiao X
- Xiotidis I
- Xu D
- Xu H
- Xu L
- Xu T
- Xu W
- Xu Z
- Yabsley B
- Yacoob S
- Yajima K
- Yallup DP
- Yamaguchi N
- Yamaguchi Y
- Yamamoto A
- Yamatani M
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang HJ
- Yang HT
- Yang S
- Yang T
- Yang X
- Yang Y
- Yao W-M
- Yap YC
- Yasu Y
- Yatsenko E
- Ye H
- Ye J
- Ye S
- Yeletskikh I
- Yexley MR
- Yigitbasi E
- Yildiz HD
- Yorita K
- Yoshihara K
- Young C
- Young CJS
- Yu J
- Yuan R
- Yue X
- Zaazoua M
- Zabinski B
- Zacharis G
- Zaffaroni E
- Zahreddine J
- Zaitsev AM
- Zakareishvili T
- Zakharchuk N
- Zambito S
- Zanzi D
- Zaripovas DR
- Zeissner S
- Zeitnitz C
- Zemaityte G
- Zeng JC
- Zenin O
- Zenis T
- Zerwas D
- Zgubic M
- Zhang B
- Zhang DF
- Zhang G
- Zhang H
- Zhang J
- Zhang L
- Zhang M
- Zhang R
- Zhang S
- Zhang X
- Zhang Y
- Zhang Z
- Zhao P
- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou M
- Zhou MS
- Zhou N
- Zhou Y
- Zhu C
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine N
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente
Discovertebral (Andersson) lesions of the spine in ankylosing spondylitis revisited
- Author
- A Calin
- A Deburge
- AB Mullaji
- AK Agarwal
- Barend J. van Royen
- BC Lentle
- BH Mahesh
- BJ Royen Van
- C Cooper
- C Nikolaisen
- C Olerud
- CH Marsh
- CM Wise
- CP Adler
- D Fang
- D McGonagle
- DJ Eschelman
- E Unsal
- EW Bergmann
- FH Shen
- FL Chan
- GQ Chance
- H Sakaura
- HB Albert
- Ho EK Chan
- Irene E. van der Horst-Bruinsma
- J Mountney
- JA Finkelstein
- JB Kenny
- JJ Rasker
- Johannes L. Bron
- KG Thorngren
- KM Lohr
- KW Chang
- KW Chang
- LS Kewalramani
- M Bourqui
- M Obradov
- Marieke N. Snieders
- MH Arnold
- MI Cawley
- MI Gelman
- Mirjam K. de Vries
- MW Fox
- N Dunn
- O Andersson
- P Frank
- P Geusens
- P Jobanputra
- PC Wu
- PW Hitchon
- R Romanus
- S Kurugoglu
- S Langlois
- S Ozgocmen
- T Hunter
- T Hunter
- TT Shih
- V Jevtic
- W Bechterew Von
- W Dihlmann
- WM Park
- Y Kabasakal
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2009
- Field of study
A well-known complication in patients with ankylosing spondylitis (AS) is the development of localised vertebral or discovertebral lesions of the spine, which was first described by Andersson in 1937. Since then, many different terms are used in literature to refer to these localised lesions of the spine, including the eponym ‘Andersson lesion’ (AL). The use of different terms reflects an ongoing debate on the exact aetiology of the AL. In the current study, we performed an extensive review of the literature in order to align communication on aetiology, diagnosis and management between treating physicians. AL may result from inflammation or (stress-) fractures of the complete ankylosed spine. There is no evidence for an infectious origin. Regardless of the exact aetiology, a final common pathway exists, in which mechanical stresses prevent the lesion from fusion and provoke the development of pseudarthrosis. The diagnosis of AL is established on conventional radiography, but computed tomography and magnetic resonance imaging both provide additional information. There is no indication for a diagnostic biopsy. Surgical instrumentation and fusion is considered the principle management in symptomatic AL that fails to resolve from a conservative treatment. We advise to use the term Andersson lesion for these spinal lesions in patients with AS
Prevalence and risk factors for diabetic retinopathy in a high-risk Chinese population
- Author
- A Bergmann
- A Grosso
- B Costa
- C Pang
- CP Wilkinson
- CY Park
- De-Hong Cai
- Department of Noncommunicable Disease Surveillance
- FH Wang
- G Liew
- G Winkler
- Guidelines subcommittee
- H Chen
- H Garcia-Alcala
- Hui Chen
- IM Stratton
- J Lindström
- J Wang
- J Xu
- JH Kang
- JH Kempen
- JH Kim
- Jia Sun
- Jiao Wang
- K Chaiyasit
- K Makrilakis
- K Makrilakis
- KJ Cruickshanks
- KM Lee
- M Franciosi
- M Rema
- MI Hellgren
- N Cheung
- OS Huang
- Q Mohamed
- R Klein
- RJ Tapp
- Rong-Ping Chen
- Ru-Yi Zhang
- Rui Yang
- T Saaristo
- T Tankova
- TK Tam
- TY Wong
- W Yang
- X Zhang
- Xiao-Yun Ke
- YH He
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A benzene-degrading nitrate-reducing microbial consortium displays aerobic and anaerobic benzene degradation pathways
- Author
- A Chang
- A Fischer
- AA Langenhoff
- AC Ulrich
- AC Ulrich
- AR Oka
- B Langmead
- B Tan
- B Tan
- B Zhu
- BJ Dean
- BM Zaan van der
- C Claudel-Renard
- C Ebenau-Jehle
- C Vogt
- CD Phelps
- D An
- D Grbic-Galic
- D Hyatt
- DE Holmes
- DE Holmes
- DH Huson
- E Díaz
- E Kopylova
- EM Top
- F Bergmann
- F Fukumori
- F Luo
- F Luo
- F Mehboob
- F Musat
- F Musat
- F Peters
- FH Harrison
- FM Duffner
- G Fuchs
- G Schmid
- H Li
- H Mouttaki
- J Frias-Lopez
- J Zedelius
- JA Valderrama
- JB Coates
- JE Butler
- JSC Liou
- JW Kung
- K Schühle
- KF Ettwig
- KF Ettwig
- KK Salinero
- L Rajeev
- LX Chen
- M Boll
- M Boll
- M Carmona
- M Kanehisa
- M Larentis
- M Martin
- M Sota
- M Taubert
- ME Caldwell
- MJ López Barragán
- MJ McInerney
- MJ Oosterkamp
- MJ Waals van der
- N Abu Laban
- N Abu Laban
- N-Y Zhou
- P Dimroth
- P Peng
- PG Egland
- PG Egland
- R Chakraborty
- R Schmieder
- RJ Didonato Jr
- RU Meckenstock
- RU Meckenstock
- S Atashgahi
- S Herrmann
- S Hunter
- S Kleinsteuber
- S Walt van der
- S Wischgoll
- SAB Weelink
- SAB Weelink
- SAB Weelink
- SF Altschul
- T Zhang
- T Zhang
- TM Vogel
- U Kunapuli
- U Kunapuli
- V Shingler
- Y Kasai
- Y Liao
- Y Moriya
- Y Peng
- Y Shi
- Y Tao
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
All sequence data from this study were deposited at the European Bioinformatics Institute under the accession numbers ERS1670018 to ERS1670023. Further, all assigned genes, taxonomy, function, sequences of contigs, genes and proteins can be found in Table S3.In this study, we report transcription of genes involved in aerobic and anaerobic benzene degradation pathways in a benzene-degrading denitrifying continuous culture. Transcripts associated with the family Peptococcaceae dominated all samples (2136% relative abundance) indicating their key role in the community. We found a highly transcribed gene cluster encoding a presumed anaerobic benzene carboxylase (AbcA and AbcD) and a benzoate-coenzyme A ligase (BzlA). Predicted gene products showed >96% amino acid identity and similar gene order to the corresponding benzene degradation gene cluster described previously, providing further evidence for anaerobic benzene activation via carboxylation. For subsequent benzoyl-CoA dearomatization, bam-like genes analogous to the ones found in other strict anaerobes were transcribed, whereas gene transcripts involved in downstream benzoyl-CoA degradation were mostly analogous to the ones described in facultative anaerobes. The concurrent transcription of genes encoding enzymes involved in oxygenase-mediated aerobic benzene degradation suggested oxygen presence in the culture, possibly formed via a recently identified nitric oxide dismutase (Nod). Although we were unable to detect transcription of Nod-encoding genes, addition of nitrite and formate to the continuous culture showed indication for oxygen production. Such an oxygen production would enable aerobic microbes to thrive in oxygen-depleted and nitrate-containing subsurface environments contaminated with hydrocarbons.This study was supported by a grant of BE-Basic-FES funds from the Dutch Ministry of Economic Affairs. The research of A.J.M. Stams is supported by an ERC grant (project 323009) and the gravitation grant “Microbes for Health and Environment” (project 024.002.002) of the Netherlands Ministry of Education, Culture and Science. F. Hugenholtz was supported by the same gravitation grant (project 024.002.002). B. Hornung is supported by Wageningen University and the Wageningen Institute for Environment and Climate Research (WIMEK) through the IP/OP program Systems Biology (project KB-17-003.02-023).info:eu-repo/semantics/publishedVersio
Adenovirus-5-Vectored P. falciparum Vaccine Expressing CSP and AMA1. Part B: Safety, Immunogenicity and Protective Efficacy of the CSP Component
- Author
- A Reyes-Sandoval
- A Reyes-Sandoval
- A Rodriguez
- AA Lal
- AK Zaiss
- AW Stowers
- Brent House
- C Cheng
- C Harro
- C. Richter King
- Carole A. Long
- Carter Diggs
- CD Harro
- CF Ockenhouse
- Chloe Wood
- Christian F. Ockenhouse
- CI Sigler
- Cindy Tamminga
- Daniel Carucci
- David Regis
- DE Brough
- Denise L. Doolan
- DF Clyde
- DH Barouch
- DL Doolan
- DL Doolan
- DL Doolan
- DL Doolan
- DL Narum
- E Peduzzi
- EH Nardin
- EM Malkin
- ES Bergmann-Leitner
- Esteban Abot
- FH Priddy
- Fouzia Farooq
- Francis T. Williams
- G Jiang
- G Minigo
- GA Oliveira
- Glenna J. Banania
- Harini Ganeshan
- Ilin Chuang
- J Liu
- J Neter
- JA Stoute
- JA Stoute
- JE Egan
- Jennylynn Lejano
- JG Beeson
- JJ Aponte
- JM Vuola
- Jose Mendoza-Silveiras
- Joseph T. Bruder
- JP Shott
- JT Bruder
- JT Bruder
- Judith E. Epstein
- K Lore
- K Marsh
- KA Bojang
- KA Kumar
- KE Kester
- KE Kester
- Keith Limbach
- KJ Limbach
- Lorraine Soisson
- M Sedegah
- M Sedegah
- MA Pierce
- Maria Belmonte
- Martha Sedegah
- MC Huaman
- MC Sprangers
- MD Spring
- Meng Shi
- MF Good
- Michael R. Hollingdale
- Michele Spring
- MJ Lockyer
- MR Hollingdale
- Nalini Manohar
- Nancy O. Richie
- Noelle B. Patterson
- O Bruna-Romero
- O Jobe
- O Silvie
- P Mettens
- P Sun
- PA Darrah
- Photini Sinnis
- R Geiben-Lynn
- R Wang
- R Wang
- RA Koup
- RA Seder
- Renato Sayo
- RM Kaufhold
- RS Nussenzweig
- RW Lindsay
- S Li
- SD Polley
- SE Bongfen
- Shannon McGrath
- Sheetij Dutta
- SJ Draper
- SJ Draper
- SL Hoffman
- SL Okitsu
- T Fandeur
- Thomas L. Richie
- U Blum-Tirouvanziam
- V Udhayakumar
- VA Stewart
- VS Moorthy
- WC Russell
- Y Charoenvit
- Y Zevering
- Publication venue
- Public Library of Science
- Publication date
- 07/10/2011
- Field of study
Background: A protective malaria vaccine will likely need to elicit both cell-mediated and antibody responses. As adenovirus vaccine vectors induce both these responses in humans, a Phase 1/2a clinical trial was conducted to evaluate the efficacy of an adenovirus serotype 5-vectored malaria vaccine against sporozoite challenge.\ud
\ud
Methodology/Principal Findings: NMRC-MV-Ad-PfC is an adenovirus vector encoding the Plasmodium falciparum 3D7 circumsporozoite protein (CSP). It is one component of a two-component vaccine NMRC-M3V-Ad-PfCA consisting of one adenovector encoding CSP and one encoding apical membrane antigen-1 (AMA1) that was evaluated for safety and immunogenicity in an earlier study (see companion paper, Sedegah et al). Fourteen Ad5 seropositive or negative adults received two doses of NMRC-MV-Ad-PfC sixteen weeks apart, at 1x1010 particle units per dose. The vaccine was safe and well tolerated. All volunteers developed positive ELISpot responses by 28 days after the first immunization (geometric mean 272 spot forming cells/million[sfc/m]) that declined during the following 16 weeks and increased after the second dose to levels that in most cases were less than the initial peak (geometric mean 119 sfc/m). CD8+ predominated over CD4+ responses, as in the first clinical trial. Antibody responses were poor and like ELISpot responses increased after the second immunization but did not exceed the initial peak. Pre-existing neutralizing antibodies (NAb) to Ad5 did not affect the immunogenicity of the first dose, but the fold increase in NAb induced by the first dose was significantly associated with poorer antibody responses after the second dose, while ELISpot responses remained unaffected. When challenged by the bite of P. falciparum-infected mosquitoes, two of 11 volunteers showed a delay in the time to patency compared to infectivity controls, but no volunteers were sterilely protected.\ud
\ud
Significance: The NMRC-MV-Ad-PfC vaccine expressing CSP was safe and well tolerated given as two doses, but did not provide sterile protection
Measurement of VH, H → b b ¯ production as a function of the vector-boson transverse momentum in 13 TeV pp collisions with the ATLAS detector
- Author
- Aaboud M
- Aad G
- Abbott B
- Abbott DC
- Abdinov O
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abud AA
- Abulaiti Y
- Acharya BS
- Adachi S
- Adam L
- Adamczyk L
- Adamek L
- Adelman J
- Adersberger M
- Adiguzel A
- Adorni S
- Adye T
- Affolder AA
- Afik Y
- Agapopoulou C
- Agaras MN
- Aggarwal A
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahmadov F
- Aielli G
- Akatsuka S
- Akesson TPA
- Akilli E
- Akimov AV
- Al Khoury K
- Alberghi GL
- Alberich LC
- Albert J
- Alconada Verzini MJ
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexandre D
- Alexopoulos T
- Alfonsi A
- Alhroob M
- Ali B
- Alimonti G
- Alison J
- Alkire SP
- Allaire C
- Allbrooke BMM
- Allen BW
- Allport PP
- Aloisio A
- Alonso A
- Alonso F
- Alpigiani C
- Alshehri AA
- Alstaty MI
- Alvarez Estevez M
- Alvarez Piqueras D
- Alviggi MG
- Amaral Coutinho Y
- Ambler A
- Ambroz L
- Amelung C
- Amidei D
- Amor Dos Santos SP
- Amoroso S
- Amrouche CS
- An F
- Anastopoulos C
- Andari N
- Andeen T
- Anders CF
- Anders JK
- Andreazza A
- Andrei V
- Anelli CR
- Angelidakis S
- Angelozzi I
- Angerami A
- Anisenkov AV
- Annovi A
- Antel C
- Anthony MT
- Antonelli M
- Antrim DJA
- Anulli F
- Aoki M
- Aparisi Pozo JA
- Arabidze G
- Araque JP
- Araujo Ferraz V
- Araujo Pereira R
- Araya ST
- Arce ATH
- Arduh FA
- Arguin J-F
- Argyropoulos S
- Arling J-H
- Armadans RC
- Armbruster AJ
- Armitage LJ
- Armstrong A
- Arnaez O
- Arnold H
- Artamonov A
- Artoni G
- Artz S
- Asai S
- Asbah N
- Asimakopoulou EM
- Asquith L
- Assamagan K
- Astalos R
- Astigarraga MEP
- Atkin RJ
- Atkinson M
- Atlay NB
- Atmani H
- Augsten K
- Avolio G
- Avramidou R
- Ayoub MK
- Azoulay AM
- Azuelos G
- Baas AE
- Baca MJ
- Bachacou H
- Bachas K
- Backes M
- Backman F
- Bagnaia P
- Bahmani M
- Bahrasemani H
- Bailey AJ
- Bailey VR
- Baines JT
- Bajic M
- Bakalis C
- Baker OK
- Bakker PJ
- Balaji S
- Baldin EM
- Balek P
- Balli F
- Balunas WK
- Balz J
- Banas E
- Bandyopadhyay A
- Banerjee S
- Bannoura AAE
- Barajas CAC
- Barak L
- Barbe WM
- Barberio EL
- Barberis D
- Barbero M
- Barillari T
- Barisits M-S
- Barkeloo J
- Barklow T
- Barnea R
- Barnes SL
- Barnett BM
- Barnett RM
- Barnovska-Blenessy Z
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- Zhemchugov A
- Zheng Z
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- Zimmermann S
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- Ziolkowski M
- Zivkovic L
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- Zorbas TG
- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2019
- Field of study
Cross-sections of associated production of a Higgs boson decaying into bottom-quark pairs and an electroweak gauge boson, W or Z, decaying into leptons are measured as a function of the gauge boson transverse momentum. The measurements are performed in kinematic fiducial volumes defined in the `simplified template cross-section' framework. The results are obtained using 79.8 fb-1 of proton-proton collisions recorded by the ATLAS detector at the Large Hadron Collider at a centre-of-mass energy of 13 TeV. All measurements are found to be in agreement with the Standard Model predictions, and limits are set on the parameters of an effective Lagrangian sensitive to modifications of the Higgs boson couplings to the electroweak gauge bosons
Measurement of the t¯tZ and t¯tW cross sections in proton-proton collisions at √s=13 TeV with the ATLAS detector
- Author
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- Aad G
- Abbott B
- Abbott DC
- Abdinov O
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- Abhayasinghe DK
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- Álvarez Piqueras D
- Åkesson TPA
- Šfiligoj T
- Ženiš T
- Živković L
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2019
- Field of study
A measurement of the associated production of a top-quark pair (t¯t) with a vector boson (W, Z) in proton-proton collisions at a center-of-mass energy of 13 TeV is presented, using 36.1 fb−1 of integrated luminosity collected by the ATLAS detector at the Large Hadron Collider. Events are selected in channels with two same- or opposite-sign leptons (electrons or muons), three leptons or four leptons, and each channel is further divided into multiple regions to maximize the sensitivity of the measurement. The t¯tZ and t¯tW production cross sections are simultaneously measured using a combined fit to all regions. The best-fit values of the production cross sections are σt¯tZ=0.95±0.08stat±0.10syst pb and σt¯tW=0.87±0.13stat±0.14syst pb in agreement with the Standard Model predictions. The measurement of the t¯tZ cross section is used to set constraints on effective field theory operators which modify the t¯tZ vertex
Search for gravitational waves from Scorpius X-1 in the second Advanced LIGO observing run with an improved hidden Markov model
- Author
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- Zimmerman Ab
- Zucker Me
- Zweizig J
- Publication venue
- College Park, MD : American Physical Society
- Publication date
- 01/01/2019
- Field of study
We present results from a semicoherent search for continuous gravitational waves from the low-mass x-ray binary Scorpius X-1, using a hidden Markov model (HMM) to track spin wandering. This search improves on previous HMM-based searches of LIGO data by using an improved frequency domain matched filter, the J-statistic, and by analyzing data from Advanced LIGO's second observing run. In the frequency range searched, from 60 to 650 Hz, we find no evidence of gravitational radiation. At 194.6 Hz, the most sensitive search frequency, we report an upper limit on gravitational wave strain (at 95% confidence) of h095%=3.47×10-25 when marginalizing over source inclination angle. This is the most sensitive search for Scorpius X-1, to date, that is specifically designed to be robust in the presence of spin wandering. © 2019 American Physical Society
Search for gravitational waves from Scorpius X-1 in the second Advanced LIGO observing run with an improved hidden Markov model
- Author
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- Zweizig J
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2019
- Field of study
We present results from a semicoherent search for continuous gravitational waves from the low-mass x-ray binary Scorpius X-1, using a hidden Markov model (HMM) to track spin wandering. This search improves on previous HMM-based searches of LIGO data by using an improved frequency domain matched filter, the J-statistic, and by analyzing data from Advanced LIGO’s second observing run. In the frequency range searched, from 60 to 650 Hz, we find no evidence of gravitational radiation. At 194.6 Hz, the most sensitive search frequency, we report an upper limit on gravitational wave strain (at 95% confidence) of h95%0=3.47×10−25 when marginalizing over source inclination angle. This is the most sensitive search for Scorpius X-1, to date, that is specifically designed to be robust in the presence of spin wandering
Pan-cancer analysis of whole genomes
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- The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium View Correspondence (jump link)
- Thiessen
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- xz Whitaker
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- Y. uz
- Y. vr
- Y. wt
- Y. yc
- ya Al-Ahmadie
- Yachida
- Yamaguchi
- Yamaguchi T. N. k
- Yamamoto
- Yamaue
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- Yang
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- Yoon
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- Yu
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- z ah
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- Z. hv
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- zd Gershenwald
- Zenklusen
- Zeps
- zf Ghossein
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang H. b
- Zhao
- Zheng
- Zhou
- Zhou
- Zhu
- Zhu
- zi zj
- zm Jayaseelan
- Zou
- Zou
- zt Kim
- zw Lewis
- Ó. A. th
- Ø. sk
- Publication venue
- Publication date
- 11/12/2019
- Field of study
Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale(1-3). Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4-5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter(4); identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation(5,6); analyses timings and patterns of tumour evolution(7); describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity(8,9); and evaluates a range of more-specialized features of cancer genomes(8,10-18).Peer reviewe
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