Transducer senses displacements of panels subjected to vibration

Inductive vibration sensor measures the surface displacement of nonferrous metal panels subjected to vibration or flutter. This transducer does not make any physical contact with the test panel when measuring

A 10-Year Experience of Therapeutic Drug Monitoring (TDM) of Linezolid in a Hospital-wide Population of Patients Receiving Conventional Dosing: Is there Enough Evidence for Suggesting TDM in the Majority of Patients?

A retrospective study was conducted to assess our 10-year experience of therapeutic drug monitoring (TDM) of linezolid in a large patient population to establish whether conventional dosing may result in adequate drug exposure in the majority of patients. Patients included in this study underwent TDM of linezolid trough concentration (Cmin ) during treatment with conventional doses of 600 mg every 12 hr in the period between January 2007 and June 2016. The desired range of Cmin was set between 2 and 7 mg/L (under-exposure, Cmin 7 mg/L). Multivariate logistic regression analysis investigated variables potentially correlated with linezolid Cmin . One thousand forty-nine patients had 2484 linezolid Cmin assessed during treatment with conventional doses. Median (IQR) linezolid Cmin was 5.08 mg/L (2.78 - 8.52 mg/L). Linezolid Cmin were within the desired range in 50.8% of cases (1262/2484). Over-exposure (n=821; 33%) occurred much more frequently than under-exposure (n=401;16.2%), and was severe (> 20 mg/L) in 3.9% of cases (98/2484). Linezolid over-exposure was significantly associated with CrCLC-G estimates 64 40 mL/min (OR 1.463; 95% CI 1.124 - 1.904, P = 0.005). Linezolid under-exposure resulted significantly associated with CrCLC-G estimates > 100 mL/min (OR 3.046; 95% CI 2.234 - 4.152, P < 0.001. Linezolid Cmin was not correlated linearly to CrCLC-G (R(2) = 0.061). Variability in renal function explained only partially the very wide interindividual linezolid Cmin variability. Our study suggests that TDM could represent a valuable approach in optimizing linezolid exposure in the majority of patients. This article is protected by copyright. All rights reserved

The Roles of Advertising and Product Quality on Online Customers' Satisfaction

The daily growth of the internet and e commerce has changed the way of marketing and selling product and service. Internet is changing the way corporation conduct business with their consumers who are increasingly expecting higher service, becoming time saved, and wanting more convenience. The Internet has significantly increased the bargaining power of consumers and to sustain in this business field, business organization need to know how to satisfy their customer. The purpose of this research is to study the factor affected customer satisfaction towards online shopping among staff at University Utara Malaysia (UUM). The objectives of the study were 1) to determine which factor more contribute in online customer satisfaction among staff in UUM and 2) to examine the relationship between online customer satisfaction and quality of advertising, and product/service quality among staff in UUM. Data were collected from 60 from academic and non-academic staff by using simple random sampling where every each element in the population will have an equal chance of being included in the sample. Further, in this study data were analyzed using SPSS version 14.0 and the tests conducted were Pearson's Correlation and multiple regression. From the correlation and multiple regression analysis, the result indicates that the factor more contribute in online customer satisfaction is a quality of advertising compared with product/service quality factor. Besides, all the factor have a significantly and positive relationship towards customer satisfaction Recommendations for future research were also discussed

Accommodating the mess : the politics of appropriation in it for others

In response to Chris Marker and Alain Resnais’s collaborative meditation on art and colonialism in Statues Also Die (1953), Duncan Campbell’s video installation It For Others (2013) takes a complex approach to presenting a Marxist criticism of the commoditization of art and culture. This article considers the intermedial and intertextual properties of It For Others as an example of convergence culture that transcends postmodern quotation and pastiche. While the film is apparently a bricolage of visual artefacts, it is in fact an intricately woven audiovisual essay concerned with the appropriation of not only colonized objects as its narration makes clear, but also of still images, moving images, written texts, sound samples, and the labour that produced them. The article examines how the film troubles notions of documentary realism and truth through its acts of appropriation that reflexively criticize the commercial appropriation and commoditization of artworks and histories. It also reflects on the film’s Marxist approach to related issues around authorship, ownership and access to artworks, particularly in the light of the film’s acknowledgement in prize culture

PENERAPAN SANKSI PIDANA BAGI PELAKU KEKERASAN SEKSUAL TERHADAP ANAK SETELAH DIBERLAKUKANNYA PERATURAN PEMERINTAH NOMOR 70 TAHUN 2020

Tujuan dilakukannya penelitian iniyaitu untuk mengetahui bagaimana pengaturan   tindak pidana kekerasan seksual terhadap anak dan bagaimana penerapan sanksi pidana bagi pelaku tindak kekerasan seksual terhadap anak setelah diberlakukannya Peraturan Pemerintah Nomor 70 Tahun 2020, di mana dengan metode penelitian hukumnormatif disimplkan: 1. Kekerasan seksual terhadap anak menurut  Undang– Undang No. 35 Tahun 2014 tentang Perubahan atas Undang–Undang No. 23 Tahun 2002 tentang Perlindungan Anak, dikategorikan menjadi  dua bagian  yaitu persetubuhan dan perbuatan cabul terhadap anak.  Pasal yang menyebutkan tentang persetubuhan dan pencabulan terhadap anak : [1]1) Pasal 76d menyebutkan tentang persetubuhan terhadap anak, yang berbunyi : “Setiap Orang dilarang melakukan Kekerasan atau ancaman Kekerasan memaksa Anak melakukan persetubuhan dengannya atau dengan orang lain”.2) Pasal 76e menyebutkan tentang perbuatan cabul terhadap anak, yang berbunyi : “Setiap Orang dilarang melakukan Kekerasan atau ancaman Kekerasan, memaksa, melakukan tipu muslihat, melakukan serangkaian kebohongan, atau membujuk Anak untuk melakukan atau membiarkan dilakukan perbuatan cabul”. Persetubuhan adalah tindakan penetrasi alat kelamin laki-laki ke dalam alat kelamin perempuan. Perbuatan cabul adalah segala bentuk perbuatan dengan alat kelamin atau bagian tubuh lainnya yang dapat merangsang libido. Kekerasan seksual tidak bisa hanya diartikan dalam hal persetubuhan saja, sebab segala bentuk kontak seksual yang dilakukan oleh orang dewasa kepada anak dianggap sebagai kekerasan seksual. 2.        Penerapan sanksi pidana terhadap pelaku kekerasan seksual terhadap anak setelah diberlakukannya Peraturan Pemerintah Nomor 70 Tahun 2020 adalah :Pertama : Pelaksanaan hukuman pokok terlebih dahulu yakni hukuman penjara dan hukuman denda sesuai keputusan pengadilan yang sudah mempunyai k ekuatan hukum yang tetap. Kemudian setelah selesai menjalani hukuman    pokok tersebut maka pelaku kekerasan seksual terhadap anak melaksanakan hukuman tambahan. Kedua : Melaksanakan hukuman tambahan yakni : Tindakan Kebiri Kimia,  pemasangan dan pelepasan alat pendeteksi elektronik, dan rehabilitasi serta               pengumuman identitas pelaku kekerasan seksual terhadap anak.Kata kunci: kekerasan seksual; anak;[1] Undang Undang No 23 Tahun 2002 Tentang Perlindungan Anak

PENGARUH UKURAN PERUSAHAAN, LEVERAGE DAN PERTUMBUHAN PENJUALAN TERHADAP TAX AVOIDANCE (Studi Pada Perusahaan Property and Real Estate yang Terdaftar di Bursa Efek Indonesia Periode 2011-2015)

ABSTRAK Penelitian ini bertujuan untuk menguji dan menganalisis secara empiris mengenai pengaruh ukuran perusahaan, leverage dan pertumbuhan penjualan pada perusahaan property and real estate yang terdaftar di Bursa Efek Indonesia pada periode 2011-2015. Faktor-faktor yang diuji dalam penelitian ini yaitu ukuran perusahaan, leverage, pertumbuhan penjualan dan tax avoidance. Metode yang digunakan dalam penelitian ini adalah metode deskriptif dan metode asosiatif. Penelitian ini menggunakan data sekunder yang diperoleh dari website IDX. Sampel yang digunakan dalam penelitian ini menggunakan teknik purposive sampling, sehingga sampel yang digunakan dalam penelitian ini berjumlah 16 perusahaan property and real estate yang terdaftar di Bursa Efek Indonesia periode 2011-2015. Pengujian hipotesis penelitian menggunakan statistik uji t (parsial) dan statistik uji f (simultan). Proses analisis statistik menggunakan SPSS 24 for Windows. Untuk mengetahui besarnya pengaruh ukuran perusahaan terhadap tax avoidance, pengaruh leverage terhadap tax avoidance, pengaruh pertumbuhan penjualan terhadap tax avoidance dan pengaruh ukuran perusahaan, leverage dan pertumbuhan penjualan terhadap tax avoidance digunakan analisis regresi logistik, analisis korelasi dan koefisien determinasi. Hasil penelitian menunjukkan bahwa ukuran perusahaan berpengaruh signifikan terhadap tax avoidance dengan persentase pengaruh sebesar 11,5%. Leverage berpengaruh signifikan terhadap tax avoidance dengan persentase pengaruh sebesar 7,3%. Pertumbuhan penjualan tidak berpengaruh signifikan terhadap tax avoidance dengan persentase pengaruh sebesar 4,3%. Ukuran perusahaan, leverage dan pertumbuhan penjualan berpengaruh signifikan terhadap tax avoidance dengan persentase pengaruh sebesar 27,3%. Kata Kunci: Ukuran Perusahaan, Leverage, Pertumbuhan Penjualan dan Tax Avoidanc

ANALISIS KETERLAKSANAAN PRAKTIKUM BIOLOGI TERHADAP HASIL BELAJAR PSIKOMOTOR PESERTA DIDIK KELAS XI IPA DI MA AL IHSAN TEMBELANG JOMBANG

ABSTRACT This study aims to determine the implementation of biology learning practicum for class XI IPA MA AL IHSAN Tembelang Jombang. This research is a qualitative descriptive study, with the research sample being students of class XI IPA randomly sampling with a total sample size of 15 students. The data collection technique was carried out by using an observation questionnaire on the activities of students in the practicum then the data were analyzed using descriptive statistics. The results showed that the results of the questionnaire for the implementation of the learning practicum with the criteria applied properly were 74.75, the results of the psychomotor assessment instruments in the group were 74.8 with good criteria, while the results of interviews with informants obtained some information that the planning of biology practicum activities was not in accordance with the existing curriculum because some obstacles. Keyword :&nbsp; Analysis, Practical work biology, psikomotor evalution &nbsp; ABSTRAK Penelitian ini bertujuan untuk mengetahui pelaksanaan praktikum pembelajaran biologi peserta didik kelas XI IPA MA AL IHSAN Tembelang Jombang. Penelitian ini merupakan penelitian deskriptif kualitatif, dengan sampel penelitian merupakan peserta didik kelas XI IPA secara random sampling dengan jumlah sampel secara keseluruhan yaitu 15 peserta didik. Teknik pengambilan data dilakukan dengan menggunakan angket pengamatan terhadap aktivitas peserta didik dalam praktikum kemudian data dianalisis dengan menggunakan statistik deskriptif. Hasil penelitian menunjukkan bahwa hasil Angket pelaksanaan praktikum pembelajaran dengan kriteria diterapkan dengan baik yaitu sebesar 74.75, hasil instrumen penilaian psikomotorik dalam kelompok sebesar 74,8 dengan kriteria baik, sedangkan hasil wawancara kepada informan diperoleh beberapa informasi bahwasanya perencanaan kegiatan praktikum biologi belum sesuai dengan kurikulum yang ada dikarenakan beberapa kendala. Kata Kunci : Analisis, Praktikum biologi, penilaian psikomotor

PROJECT BASED LEARNING BERBASIS STEM DESIGN THINKING PROCESS UNTUK MENINGKATKAN HASIL BELAJAR MAHASISWA PENDIDIKAN BIOLOGI PADA MATAKULIAH BIOLOGI UMUM

&nbsp;ABSTRACT General Biology course learning material on the basics of Genetics in the Biology Education Study Program, University of KH. A. Wahab Hasbullah, where the learning process is still just to remember and understand so that it is focused on memorizing the material, then the learning process has not maximally utilized the information technology and multimedia use that integrates STEM learning models, and the learning process has not reflected the empowerment of critical thinking skills in students, and also the low average student learning outcomes in the previous material. So the solution to the finding of the problem is to apply the PjBL model based on the STEM Design Thinking Process. The research method uses Pre-Experimental Design, One Group Pretest Postest Design research design, then analyzes data including validity test, reliability test, learning outcome value, hypothesis testing through normality test, homogeneity test and paired t-test it was found that Ho was rejected and Ha was accepted. So there is the effect of project based learning based on STEM design thinking process to improve student learning outcomes in biology education. KEYWORDS: project based learning, STEM design thinking process, learning outcome &nbsp; &nbsp;ABSTRAK Pembelajaran matakuliah Biologi Umum materi dasar-dasar Genetika&nbsp; di Program Studi Pendidikan Biologi Universitas KH. A. Wahab Hasbullah, dimana dalam proses pembelajaran masih sekedar mengingat dan memahami sehingga terfokus pada hafalan materinya saja, kemudian proses pembelajaran belum memanfaatkan secara maksimal adanya teknologi informasi dan penggunaan multimedia yang mengintegrasikan model pembelajaran STEM, dan proses&nbsp; pembelajaran belum mencerminkan pemberdayaan keterampilan berpikir kritis pada mahasiswa, dan juga rendahnya rerata hasil belajar mahasiswa pada materi sebelumnya. Sehingga solusi atas temuan masalah tersebut adalah menerapkan model PJBL berbasis STEM Design Thinking Process. Metode penelitian menggunakan Pre-Experimental Design, desain penelitian One Group Pretest Postest Design, kemudian menganalisis data antara lain uji validitas, uji reabilitas, nilai hasil belajar, uji hipotesis melalui uji normalitas, uji homogenitas dan uji statistik paired t-test (t berpasangan) yang diperoleh bahwa Ho ditolak dan Ha diterima. Jadi terdapat pengaruh project based learning berbasis STEM design thinking process untuk meningkatkan hasil belajar mahasiswa pendidikan biologi. Kata kunci : project based learning, STEM design thinking process, hasil belajar &nbsp

Antimicrobial Dose Reduction in Continuous Renal Replacement Therapy: Myth or Real Need? A Practical Approach for Guiding Dose Optimization of Novel Antibiotics

Acute kidney injury represents a common complication in critically ill patients affected by septic shock and in many cases continuous renal replacement therapy (CRRT) may be required. In this scenario, antimicrobial dose optimization is highly challenging as the extracorporeal circuit may cause several pharmacokinetic alterations, which add up to volume of distribution and clearance variations resulting from sepsis. Variations in CRRT settings (i.e. modality of solute removal, type of filter material, blood flow rate and effluent flow rate), coupled with the presence of residual and/or recovering renal function, may cause dynamic variations in the clearance of hydrophilic antimicrobials. This means that dose reduction may not always be needed. Nowadays, the lack of pharmacokinetic data for novel antimicrobials during CRRT limits evidence-based dose recommendations for critically ill patients in this setting, thus making available evidence hardly applicable in real-world scenarios. This review aims to summarize the major determinants involved in antimicrobial clearance, and the available pharmacokinetic studies performed during CRRT involving novel antibiotics used for the management of multidrug-resistant Gram-positive and Gram-negative infections (namely ceftolozane–tazobactam, ceftazidime–avibactam, cefiderocol, imipenem–relebactam, meropenem–vaborbactam, ceftaroline, ceftobiprole, dalbavancin, and fosfomycin), providing a practical approach in guiding dose optimization in this special population