9 research outputs found
Thermomechanical Pulp Bleaching Optimization Via Dimethyldioxirane
- Author
- Publication venue
- ScholarWorks at WMU
- Publication date
- 01/04/1996
- Field of study
In recent years, the paper industry has received increased pressure from environmental groups to reduce both air-borne & water-borne discharges. During element-chlorine bleaching processes, absorbable organic halides are formed , some of which are considered harmful to aquatic life. To reduce absorbable organic halides, many mills are moving towards chlorine-free bleaching stages. A potential chlorine-free bleaching agent is dimethyldioxirane. Dimethyldioxirane is an intermediate produced in-situ from acetone and peroxymonosulfate. Due to the bond strain of the oxygen-oxygen bond in this cyclic peroxide, it behaves as a strong oxidizing agent.
The goal of this thesis was to determine the optimum levels of pH, dimethyldioxirane charge, and bleaching time for a thermomechanical pulp. It was determined that the optimum brightness of 40% could be reached at a pH of 8, charge level of 9%, and by bleaching for 30 minutes. This same brightness could be obtained by using two 2.5% (5%-split) dimethyldioxirane bleaching stages in-lieu of one 9% stage. When a 4% hydrogen peroxide stage is added to the optimized 5%-split run, a maximum brightness of 58.3% could be obtained.
A linear correlation between pulp yield and brightness was found until the pulp yield dropped below 82%. At this point, as the yield decreased, the brightness remained constant. There appeared to be no decrease in zero-span tensile index as the charge addition level was increased
Genome-wide Analyses Identify KIF5A as a Novel ALS Gene
- Author
- A. Nazli Basak
- A. Nazli Basak
- Aaron D. Gitler
- Aaron D. Gitler
- Aaron G. Day-Williams
- Adriano Chio
- Adriano Chiò
- Ahmad Al Kheifat
- Alan E. Renton
- Albert C. Ludolph
- Alberto Garcia Redondo
- Alberto GarcĂa-Redondo
- Alberto M. Rivera
- Aleksey Shatunov
- Aleksey Shatunov
- Alessandra Chesi
- Alessandro Arosio
- Alex LeNail
- Alexander LeNail
- Alexander Sherman
- Alexis Brice
- Alfredo Iacoangeli
- Alya R. Raphael
- Amelia Conte
- Ammar Al-Chalabi
- Ammar Al-Chalabi
- Andrea Calvo
- Andrea Calvo
- Andrea Malaspina
- Andrea Malaspina
- Andrea Swenson
- Andrew B. Singleton
- Andrew King
- Andrew S. Allen
- Angela L. Jones
- Angelo Pirisi
- Anna Ticca
- Anne Cooley
- Anneloor L.M.A. ten Asbroek
- Annelot Dekker
- Antonia Ratti
- Antonia Ratti
- Antonino Cannas
- Antonio Canosa
- Antonio Fasano
- Antonio Ilardi
- Antonio Milia
- Antonio Petrucci
- Aoife Kenna
- Athina Soragia Gkazi
- Aude Nicolas
- Avinash Abhyankar
- Avindra Nath
- Barbara Castellotti
- Barbara Poletti
- Bas Middelkoop
- Bas Middelkoop
- Braden E. Boone
- Bradley N. Smith
- Brendan J. Kenna
- Brian J. Krueger
- Brittany N. Lasseigne
- Bryan J. Traynor
- Carla Caredda
- Carla Pani
- Carlayne Jackson
- Carlo Ferrarese
- Caroline Vance
- Chris Shaw
- Christian Lunetta
- Christian Lunetta
- Christine Clayman
- Christopher B. Brady
- Christopher E. Shaw
- Cinzia Bertolin
- Cinzia Femiano
- Cinzia Gellera
- Cinzia Gellera
- Cinzia Tiloca
- Cinzia Tiloca
- Claire Troakes
- Claudia Caponnetto
- Claudia Caponnetto
- Claudia Colombrita
- Claudia Ricci
- Clive N. Svendsen
- Clive N. Svendsen
- Corey McMillan
- Cristiane de Araujo Martins Moreno
- Cristina Cereda
- Cristina Cereda
- Cristina Moglia
- Daniel J. MacGowan
- Daniel J.L. MacGowan
- Daniela Corongiu
- Daniela Loi
- David B. Goldstein
- David B. Goldstein
- David B. Goldstein
- David J. Stone
- David Lacomis
- David Walk
- Dena G. Hernandez
- Denis C. Bauer
- Dhruv Sareen
- Dhruv Sareen
- Diane McKenna-Yasek
- Diane McKenna-Yasek
- Edward B. Lee
- Efthimios Dardiotis
- Ekaterina Rogaeva
- Elizabeth T. Cirulli
- Emanuela Costantino
- Emilien Bernard
- Emily Baxi
- Emily Baxi
- Emmeline Lagrange
- Enzo Ortu
- Eran Hornstein
- Ericka Simpson
- Ericka Simpson
- Erik P. Pioro
- Erik Pioro
- Ernest Fraenkel
- Ernest Fraenkel
- Ernest Fraenkel
- Eva L. Feldman
- Evadnie Rampersaud
- Evadnie Rampersaud
- Fabio Giannini
- Fabiola De Marchi
- Fabrizio Pisano
- Fabrizio Salvi
- Fabrizio Salvi
- Faraz Faghri
- Federico Casale
- Federico Verde
- Federico Verde
- Francesca L. Conforti
- Francesca L. Conforti
- Francesca Trojsi
- Francesca Trojsi
- Francesco Landi
- Francesco Marrosu
- Francesco O. Logullo
- Francesco O. Logullo
- Franco Taroni
- Franco Taroni
- Frank Baas
- Frank Baas
- Freya Kamel
- Gabriele Mora
- Gabriele Mora
- Gabriele Siciliano
- Gabriella Restagno
- Gang Wu
- Gang Wu
- Garth A. Nicholson
- George Manousakis
- Giacomo P. Comi
- Giacomo P. Comi
- Giancarlo Logroscino
- Gianluca Floris
- Gianluigi Mancardi
- Gianni SorarĂą
- Gianni SorarĂą
- Gijs Tazelaar
- Gioacchino Tedeschi
- Giorgia Querin
- Giovanni Piccirillo
- Giuseppe Borghero
- Giuseppe Borghero
- Giuseppe Fuda
- Giuseppe Lauria
- Giuseppe Lauria
- Giuseppe Lauria Pinter
- Giuseppe Marangi
- Giuseppe Marangi
- Giuseppe Marrali
- Glenn Gerhard
- Gregory A. Cox
- Gregory M. Cooper
- Guy A. Rouleau
- Guy A. Rouleau
- Gwendal Lemasson
- GĂ©rard Besson
- Hannah A. Pliner
- Hannu Laaksovirta
- Hemali Phatnani
- Hemali Phatnani
- Hisham Hamdalla
- Ian P. Blair
- Ian P. Blair
- Ilaria Bartolomei
- Irene Ossola
- Isabella Fogh
- Isabella Fogh
- Isabella L. Simone
- Isabella Simone
- Isabelle Le Ber
- J. Paul Taylor
- J. Paul Taylor
- J. Raphael Gibbs
- Jack R. Wimbish
- Jacob McCauley
- Jacqueline de Belleroche
- James Broach
- James Caress
- James D. Berry
- James D. Berry
- James D. Berry
- James R. Broach
- Jan H. Veldink
- Jan Veldink
- Janel O. Johnson
- Janice A. Dominov
- Janine Kirby
- Jaya Trivedi
- Jeannine Heckmann
- Jeffrey D. Rothstein
- Jeffrey D. Rothstein
- Jeffrey Statland
- Jennifer A. Fifita
- Jennifer E. Van Eyk
- Jenny Van Eyk
- Jessica Mandrioli
- Jessica Mandrioli
- Jesus Mora Pardina
- JesĂşs Esteban-PĂ©rez
- JesĂşs S. Mora
- Jinghui Zhang
- Jinhui Ding
- Joanne Wuu
- Joanne Wuu
- Jochen H. Weishaupt
- John D. Eicher
- John E. Landers
- John Ealing
- John F. Staropoli
- John Hardy
- John Landers
- John M. Ravits
- John M. Ravits
- John P. Carulli
- John Q. Trojanowski
- John Ravits
- Johnathan Cooper-Knock
- Joke J.F.A. van Vugt
- Joke van Vugt
- Jonathan Cooper-Knock
- Jonathan D. Glass
- Jonathan D. Glass
- Jonathan D. Glass
- Jonathan Glass
- Jonathan Katz
- Jonathan Keebler
- Jonathan Mill
- Joshua Dubnau
- Joshua T. Geiger
- José Luis Muñoz-Blanco
- Juan C. Troncoso
- Julia Kaye
- Julia Kaye
- Julien Couthouis
- Justin Kwan
- Kalliopi Marinou
- Karen E. Morrison
- Karen Morrison
- Katherine B. Sims
- Katie C. Sidle
- Kelly Gwathmey
- Kelly L. Williams
- Kelly L. Williams
- Kevin B. Boylan
- Kevin Kenna
- Kevin Mouzat
- Kevin Mouzat
- Kevin P. Kenna
- Kevin Talbot
- Kristel R. Van Eijk
- Kristel van Eijk
- Lauren Elman
- Leandro Lima
- Leandro Lima
- Leo Wang
- Leonard H. van den Berg
- Leonard van den Berg
- Leslie D. Parish
- Leslie M. Thompson
- Leslie M. Thompson
- Leslie M. Thompson
- Letizia Mazzini
- Letizia Mazzini
- Liberty Jenkins
- Liisa Myllykangas
- Lilja Jansson
- Lindsay L. Waite
- Lorena Mosca
- Lorne Zinman
- Luca Maderna
- Lucia Corrado
- Lucia Corrado
- Lucie Bruijn
- Lucio Tremolizzo
- Ludo Van Den Bosch
- Luigi Ferrucci
- Lyle W. Ostrow
- Lyle W. Ostrow
- Maarten Kooyman
- Maarten Kooyman
- Mamede de Carvalho
- Mamede de Carvalho
- Marc Gotkine
- Marcella Zollino
- Marco Barberis
- Marco Luigetti
- Margherita Capasso
- Margherita Capasso
- Maria Giovanna Marrosu
- Maria Rita Murru
- Maria Rosaria Monsurrò
- Marialuisa Santarelli
- Marielle Wallace
- Mario Sabatelli
- Mario Sabatelli
- Marka Van Blitterswijk
- Markus Weber
- Markus Weber
- Martin R. Turner
- Mary Kay Floeter
- Massimiliano Filosto
- Massimo Corbo
- Matthew B. Harms
- Matthew B. Harms
- Matthew B. Harms
- Matthew Kiernan
- Matthieu Moisse
- Mattieu Moisse
- Maura Brunetti
- Maura Pugliatti
- Maurizio Grassano
- Maurizio Inghilleri
- Maurizio Melis
- Mauro Ceroni
- Mayana Zatz
- Meraida Polak
- Merit Cudkowicz
- Merit Cudkowicz
- Michael A. Van Es
- Michael Benatar
- Michael Benatar
- Michael C. Zody
- Michael van Es
- Michele Benigni
- Michelle Penny
- Miguel Mitne Neto
- Mike A. Nalls
- Miko Valori
- Molly G. Hammell
- Natalie A. Murphy
- Natalie A. Twine
- Nathalie Guy
- Neil A. Shneider
- Neil A. Shneider
- Neil A. Shneider
- Neil W. Kowall
- Nicholas J. Maragakis
- Nicholas J. Maragakis
- Nicola Fini
- Nicola Ticozzi
- Nicola Ticozzi
- Nicola Ticozzi
- Nikolaos A. Patsopoulos
- Nilo Riva
- Nilo Riva
- Noah Zaitlen
- null Shankaracharya
- Orla Hardiman
- Orla Hardiman
- Pamela J. Shaw
- Pamela Keagle
- Pamela Shaw
- Paola Carrera
- Paola Mandich
- Paola Origone
- Paolo Volanti
- Paolo Volanti
- Patrick A. Dion
- Patrick Vourch
- Patrizia Occhineri
- Pentti Tienari
- Peter Andersen
- Peter C. Sapp
- Peter C. Sapp
- Peter M. Andersen
- Philip Van Damme
- Philip van Damme
- Philippe Corcia
- Philippe Corcia
- Philippe Corcia
- Philippe Couratier
- Philippe Couratier
- Pierre Clavelou
- Pietro Fratta
- Pietro Fratta
- Quanli Wang
- Raffaella Tanel
- Rajeeva Lochan Musunuri
- Rebecca Schule
- Riccardo Sideri
- Richard Barohn
- Richard Bedlack
- Richard M. Myers
- Richard M. Myers
- Richard S. Bedlack
- Richard W. Orrell
- Rick A. Van der Spek
- Rick van der Spek
- Robert Bowser
- Robert Brown
- Robert H. Baloh
- Robert H. Baloh
- Robert H. Baloh
- Robert H. Baloh
- Robert H. Brown
- Roberta Puddu
- Roberto Del Bo
- Roger Pamphlett
- Rosa Rademakers
- Rosa Rademakers
- Rossella Spataro
- Roy H. Campbell
- Russell L. McLaughlin
- Russell McLaughlin
- Ruth Chia
- Safa Al-Sarraj
- Sampath Arepalli
- Samuel Maiser
- Sandra D’Alfonso
- Sandra D’Alfonso
- Sara Pulit
- Sara Rollinson
- Sebastian D. Hayes
- Sebastiano Cavallaro
- Seneshaw Asress
- Serena Lattante
- Serge Lumbroso
- Serge Lumbroso
- Shaida Khan
- Shawn E. Levy
- Siddharthan Chandran
- Siddharthan Chandran
- Silvana Penco
- Silvia Peverelli
- Simon D. Topp
- Sitharthan Kamalakaran
- Slavé Petrovski
- Sonia Messina
- Sonja W. Scholz
- Stacia K. Wyman
- Stacia Wyman
- Stanley Appel
- Stanley H. Appel
- Stefan M. Pulst
- Stefan M. Pulst
- Stefania Battistini
- Stefania Battistini
- Stefania Cammarosano
- Stefania Corti
- Stefania Cuccu
- Stefania Tranquilli
- Stefania Tranquilli
- Stella Gagliardi
- Stephan ZĂĽchner
- Stephen A. Goutman
- Stephen Goutman
- Stephen J. Kolb
- Stephen J. Kolb
- Stephen Newhouse
- Steve Finkbeiner
- Steven Finkbeiner
- Steven Finkbeiner
- Stuart Pickering-Brown
- Sumaira Hussain
- Summer B. Gibson
- Summer Gibson
- Summer Gibson
- Susana Pinto
- Suvankar Pal
- Suvankar Pal
- Tea B. Cau
- Ted Burns
- Terry D. Heiman-Patterson
- Terry Heiman-Patterson
- Thomas Meitinger
- Tim Harris
- Tim Harris
- Tim M. Strom
- Timothy M. Miller
- Timothy M. Miller
- Timothy M. Miller
- Timothy M. Miller
- Timothy M. Miller
- Tiziana Colletti
- Tom Maniatis
- Travis L. Dunckley
- Uday Shankar Evani
- Umberto Manera
- Valeria Piras
- Vincent Meininger
- Vincenzo La Bella
- Vincenzo La Bella
- Vincenzo Silani
- Vincenzo Silani
- Vincenzo Silani
- Vivian Drory
- Vivian E. Drory
- Viviana Pensato
- Vivianna M. Van Deerlin
- Vivianna M. Van Deerlin
- VĂ©ronique Danel
- Wendy K. Chung
- William Camu
- William Camu
- William Sproviero
- Wim Robberecht
- Wim Robberecht
- Winnie W. Xin
- Winston Hide
- Wouter van Rheenen
- Wouter van Rheenen
- Ximena Arcila-Londono
- Yevgeniya Abramzon
- Yi-Fan Lu
- Yuen So
- Yujun Han
- Zachary Simmons
- Zachary Simmons
- Zachary Simmons
- Zhong Ren
- Publication venue
- Publication date
- 01/01/2018
- Field of study
To identify novel genes associated with ALS, we undertook two lines of investigation. We carried out a genome-wide association study comparing 20,806 ALS cases and 59,804 controls. Independently, we performed a rare variant burden analysis comparing 1,138 index familial ALS cases and 19,494 controls. Through both approaches, we identified kinesin family member 5A (KIF5A) as a novel gene associated with ALS. Interestingly, mutations predominantly in the N-terminal motor domain of KIF5A are causative for two neurodegenerative diseases: hereditary spastic paraplegia (SPG10) and Charcot-Marie-Tooth type 2 (CMT2). In contrast, ALS-associated mutations are primarily located at the C-terminal cargo-binding tail domain and patients harboring loss-of-function mutations displayed an extended survival relative to typical ALS cases. Taken together, these results broaden the phenotype spectrum resulting from mutations in KIF5A and strengthen the role of cytoskeletal defects in the pathogenesis of ALS.Peer reviewe
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease
- Author
- Aaberge
- Abdelmoneim
- Abernethy
- Abidov
- Abizaid
- Abrams
- Abrams
- Agatston
- Agelink
- Akhtar
- Akram
- Al Suwaidi
- Al-Mallah
- Alan L. Hinderliter
- Albert
- Alderman
- Alderman
- Alderman
- Alderman
- Alexander
- Allen
- Allen
- Allen
- Alter
- Ambrose
- America
- America
- Amin
- Anand
- Anavekar
- Anderson
- Angelini
- Antman
- Antman
- Antman
- Antman
- Apostolos P. Dallas
- Appel
- Appel
- Appel
- Appel
- Arnesen
- Arnlov
- Arnold
- Arnold
- Arora
- Artinian
- Aubry
- Avendano
- Avezum
- Azevedo
- Aziz
- Badran
- Bae
- Baigent
- Balady
- Ballegaard
- Ballegaard
- Balsano
- Bandura
- Bangalore
- Banning
- Barsness
- Bateman
- Baumhakel
- Bazzano
- Beckett
- Bell
- Bello
- Beltrame
- Ben-Gal
- Benedetto
- Beniamini
- Benzer
- Berger
- Berkman
- Berman
- Berman
- Berman
- Berman
- Bernheim
- Bernstein
- Berrington de Gonzalez
- Berrington de Gonzalez
- Bhatt
- Bhatt
- Bhatt
- Bhatt
- Biagini
- Bingham
- Biondi-Zoccai
- Bjelakovic
- Bjork Ingul
- Blankstein
- Blendea
- Block
- Blomkalns
- Blumenthal
- Boberg
- Boden
- Bodi
- Boekholdt
- Bogers
- Bohlen
- Boman
- Bonaa
- Bonaros
- Bonatti
- Bonnet
- Bonow
- Bonow
- Bonow
- Borer
- Borger van der Burg
- Borjesson
- Bosworth
- Bottcher
- Boudriot
- Bourassa
- Bouzas-Mosquera
- Bouzas-Mosquera
- Bozzette
- Braunwald
- Braunwald
- Braunwald
- Braunwald
- Bravata
- Brener
- Brener
- Brener
- Brenner
- Bridges
- Briguori
- Brogden
- Brook
- Brophy
- Brorsson
- Brosius
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- Brown
- Bruder
- Brunelli
- Bucher
- Buckley
- Buckley
- Budoff
- Bugiardini
- Burkhoff
- Buse
- Buszman
- Byzova
- Cademartiri
- Califf
- Califf
- Califf
- Calle
- Calnon
- Cameron
- Cameron
- Camm
- Campeau
- Campeau
- Canner
- Cannon
- Cannon
- Capodanno
- Caracciolo
- Cardinal
- Carnethon
- Carney
- Carney
- Carney
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- Carrie
- Cashin
- Caulin-Glaser
- Cecil
- Cecil
- Cerqueira
- Chaitman
- Chaitman
- Chaitman
- Chaitman
- Chakravarty
- Chan
- Chaowalit
- Charatan
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- Chatziioannou
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- Cheng
- Cheng
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- Chow
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- Christopher
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- Clark
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- Cole
- Coleman
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- Conley
- Cortigiani
- Couch
- Craig R. Smith
- Critchfield
- Critchley
- Critchley
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- Davies
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- Eisenstein
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- Emond
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- Every
- Ezekowitz
- Farkouh
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- Feit
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- Fesmire
- Feuchtner
- Fiechter
- Fisher
- Fleischmann
- Fleisher
- Fletcher
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- Fraker
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- Franzen
- Frasure-Smith
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- Freemantle
- Friis-Moller
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- Hachamovitch
- Hachamovitch
- Hachamovitch
- Hachamovitch
- Hachamovitch
- Hachamovitch
- Hacker
- Haffner
- Haffner
- Halliburton
- Hallikainen
- Halpern
- Hambrecht
- Hambrecht
- Hambrecht
- Hamdan
- Hamm
- Hammermeister
- Hamon
- Hamon
- Hamon
- Hannan
- Hannan
- Hannan
- Harlan M. Krumholz
- Harris
- Hashimoto
- Haskell
- Haskell
- Hauf-Zachariou
- Hautvast
- Hautvast
- He
- Hebert
- Heidenreich
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- Held
- Helton
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- Hemmelgarn
- Hendel
- Hendel
- Henderson
- Henderson
- Henneman
- Herzog
- Heslop
- Hillis
- Hirsh
- Hlatky
- Hlatky
- Hlatky
- Hlatky
- Ho
- Ho
- Ho
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- Hollander
- Holman
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- Holmes
- Holubkov
- Holzhey
- Homcy
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- Hong
- Honig
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- Hosokawa
- Hsieh
- Hubbard
- Hueb
- Hueb
- Hueb
- Hueb
- Hughes
- Hughes
- Hulley
- Hundley
- Hunt
- Iafrate
- Imran
- Ingkanisorn
- Innocenti
- Ishikawa
- Isner
- Ix
- Jacobs
- Jacobs
- Jaffery
- Jagathesan
- Jahnke
- James C. Blankenship
- Jane A. Linderbaum
- Janne d'Othee
- Janosi
- Javaid
- Javitz
- Jensen
- Jerling
- Jneid
- Jneid
- Joanna D. Sikkema
- JoAnne M. Foody
- Joannides
- Johansen
- John A. Spertus
- Johnson
- Johnson
- Jonathan Abrams
- Jones
- Jones
- Jones
- Jones
- Jorenby
- Joseph F. Sabik
- Jouven
- Julius
- Julius M. Gardin
- Jurca
- Juul-Moller
- Juurlink
- Kaiser
- Kamalesh
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- Kannel
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- Karlsson
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- Kathleen Berra
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- Kim
- Kim
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- King
- King
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- Kleisli
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- Knochel
- Knudtson
- Ko
- Ko
- Kober
- Koh
- Kok
- Kon
- Koo
- Kop
- Korosoglou
- Koyanagi
- Kozower
- Krepp
- Kroenke
- Krolewski
- Kronish
- Krumholz
- Kuntz
- Kunz
- Kushner
- Kwok
- Kwok
- Kwong
- Kwong
- Lacoste
- Ladapo
- Ladenheim
- Ladenheim
- Laghrissi-Thode
- Laing
- Lancaster
- Lang
- Lapenna
- LaRosa
- Larson
- Lauer
- Lauer
- Lauer
- Lavie
- Leape
- Lee
- Lee
- Lee
- Lee
- Lee
- Lee
- Leischik
- Leizorovicz
- Leon
- Leon
- Lerakis
- Lertsburapa
- Leslee J. Shaw
- Lesperance
- Levine
- Levy
- Levy
- Levy
- Lewington
- Lewis
- Li
- Liao
- Libby
- Lichtenstein
- Lichtman
- Lima
- Lin
- Lin
- Little
- Liu
- Liu
- Lloyd-Jones
- Loke
- Lonn
- Lonn
- Loop
- Lopez-Jimenez
- Lorenzoni
- Lytle
- MacGregor
- Maddox
- Mahajan
- Makikallio
- Malenka
- Malfatto
- Mannheimer
- Manolio
- Manson
- Manson
- Manz
- Manzi
- Maqbool
- Marcassa
- Mark
- Mark
- Mark
- Mark
- Mark A. Munger
- Markham
- Maron
- Martini
- Martuscelli
- Marwick
- Marwick
- Marwick
- Marwick
- Marzilli
- Mason
- Matetzky
- Mattera
- Matzkies
- Mauri
- May
- McCartney
- McCord
- McCormack
- McCully
- McCully
- McFadden
- McGillion
- McKellar
- McLellan
- McManus
- McMurray
- McNulty
- McTigue
- Mega
- Mega
- Mehran
- Mehta
- Meijboom
- Melin
- Mensah
- Merz
- Messerli
- Metz
- Michael J. Lim
- Michael J. Mack
- Mieres
- Milani
- Miller
- Miller
- Miller
- Miller
- Miller
- Miller
- Min
- Min
- Min
- Min
- Min
- Min
- Mock
- Moe
- Moller
- Montalescot
- Montorsi
- Morice
- Morise
- Morris
- Morrison
- Morrow
- Morrow
- Morrow
- Mosca
- Moscucci
- Moss
- Motoyama
- Motoyama
- Moussavi
- Mowatt
- Mowatt
- Mozaffarian
- Mukamal
- Mukamal
- Mukherjee
- Muller
- Mulvagh
- Muntwyler
- Munzel
- Munzel
- Murphy
- Murphy
- Murray
- Murthy
- Musselman
- Muszbek
- Myers
- Myers
- Myers
- Myers
- Myers
- Nagao
- Nagata
- Nagel
- Naik
- Naimi
- Nakagomi
- Nakata
- Nallamothu
- Nallamothu
- Nallamothu
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- Nandalur
- Narahara
- Nathan
- Navare
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- Ng
- Nguyen
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- Nieminen
- Nigam
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- Niles
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- Nowak
- Nucifora
- Nygard
- O'Connor
- O'Donoghue
- O'Donoghue
- O'Keefe
- O'Rourke
- O'Shaughnessy
- Oesterle
- Oka
- Okin
- Okin
- Oldridge
- Oremus
- Ornish
- Osswald
- Otero
- Ovrehus
- Packer
- Packer
- Padma-nathan
- Palmerini
- Pamela S. Douglas
- Pare
- Paridon
- Parisi
- Park
- Park
- Park
- Parker
- Parker
- Parmley
- Passamani
- Patel
- Patel
- Paul D. Kligfield
- Pazhenkottil
- Pazhenkottil
- Pazhenkottil
- Pedersen
- Pekkanen
- Pennell
- Pepine
- Pepine
- Perrone-Filardi
- Peteiro
- Peteiro
- Peters
- Peterson
- Peterson
- Peterson
- Pfautsch
- Pfeffer
- Pfisterer
- Pfisterer
- Phillips
- Philpott
- Pi-Sunyer
- Picano
- Pijls
- Pilz
- Pilz
- Pinkstaff
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- Pitt
- Pitt
- Pitt
- Pittman
- Plotnick
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- Pocock
- Pohl
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- Poldermans
- Pollock
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- Poole-Wilson
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- Pope
- Pope
- Porter
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- Pryor
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- Qureshi
- Raff
- Raftery
- Ragosta
- Rajaratnam
- Rao
- Rauramaa
- Ray
- Raymond Y.K. Kwong
- Reddan
- Rees
- Reeves
- Rehnqvist
- Reichard
- Reicher
- Reid
- Resnic
- Richard L. Prager
- Richter
- Riddler
- Ridker
- Rieckmann
- Rieckmann
- Rigotti
- Riley
- Rimm
- Rimm
- Ringqvist
- Rocha-Filho
- Rodes-Cabau
- Rodriguez
- Rodriguez
- Rodriguez
- Rodriguez
- Roger
- Romero-Corral
- Rosendorff
- Rosengren
- Rossouw
- Rossouw
- Rouleau
- Rousseau
- Rozanski
- Rozanski
- Rozanski
- Ruberman
- Rubins
- Rubinshtein
- Rudisch
- Rumsfeld
- Rumsfeld
- Rumsfeld
- Rumsfeld
- Rumsfeld
- Ruo
- Rutledge
- Ryden
- Sabharwal
- Sachdev
- Sacks
- Sacks
- Sakuma
- Sakuma
- Sampson
- Sankey V. Williams
- Sanmartin
- Santana-Boado
- Sarnak
- Sarwar
- Savonitto
- Saw
- Sawada
- Sawada
- Schaefer
- Schaefer
- Schappert
- Schinkel
- Schleifer
- Schofield
- Schomig
- Schuetz
- Schuijf
- Schuler
- Schwitter
- Scirica
- Sebrechts
- Sedlis
- Selvin
- Sergeant
- Serruys
- Serruys
- Serruys
- Seung
- Sever
- Shah
- Shah
- Shahian
- Shahian
- Sharaf
- Sharir
- Sharir
- Sharir
- Sharir
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shaw
- Shechter
- Shepherd
- Sherwood
- Shimbo
- Shmilovich
- Shreibati
- Shroyer
- Shuldiner
- Sidney C. Smith
- Sierksma
- Sievers
- Silagy
- Silber
- Siller-Matula
- Simari
- Simon
- Simoons
- Singh
- Singh
- Singh
- Sirois
- Sjostrom
- Skyler
- Slomka
- Slomka
- Sloth-Nielsen
- Small
- Smith
- Smith
- Smith
- Smith
- Soejima
- Sofowora
- Sorajja
- Sowers
- Sox
- Spaulding
- Spencer B. King
- Spertus
- Spertus
- Spertus
- Spertus
- Spertus
- Spertus
- Staessen
- Stamler
- Stamler
- Stamou
- Stampfer
- Stampfer
- Stampfer
- Stead
- Stead
- Steel
- Stein
- Steinhubl
- Stephan
- Stephan D. Fihn
- Stephens
- Stevens
- Stevens
- Stone
- Stone
- Stratmann
- Stroupe
- Stys
- Subramanian
- Sullivan
- Sun
- Sun
- Szczech
- Tabib
- Taillefer
- Takaro
- Takaro
- Tamaki
- Tamburino
- Tan
- Tanaka
- Tandogan
- Tarakji
- Tarantini
- Tardif
- Tatti
- Taylor
- Taylor
- Taylor
- Taylor
- Taylor
- Taylor
- Taylor
- Tepper
- Thiele
- Thiele
- Thomas
- Thomas C. Gerber
- Thompson
- Thompson
- Timmis
- Todd
- Tonino
- Toole
- Topol
- Treese
- Trikalinos
- Trikalinos
- Tsuya
- Tsuyuki
- Tummala
- Tuomilehto
- Turnbull
- Turnbull
- Turnbull
- Underwood
- Underwood
- Underwood
- Urano
- Ussher
- Vaccarino
- Vaccarino
- Valdiviezo
- Van Camp
- van der Bijl
- van der Sloot
- van Rij
- van Velzen
- van Werkhoven
- VandenBurg
- Varani
- Vardeny
- Varnauskas
- Vassiliades
- Velazquez
- Villarruz
- Villines
- Vineberg
- Vitarelli
- Vivekananthan
- von Arnim
- von Beckerath
- Vongvanich
- Wagdy
- Wahrborg
- Wallace
- Wallentin
- Waters
- Waysbort
- Weiner
- Weiner
- Weintraub
- Weintraub
- Weintraub
- Wenaweser
- West
- Whelton
- Whelton
- Whelton
- White
- Whooley
- Whooley
- Wiest
- Wight
- Wijeysundera
- Wijeysundera
- Wijns
- Willett
- Wilson
- Wilt
- Winniford
- Winter
- Wiviott
- Wong
- Woodcock
- Worm
- Wright
- Wright
- Wu
- Xie
- Xin
- Yang
- Yang
- Yao
- Yao
- Yao
- Yoshinaga
- Yoshinaga
- Yu-Poth
- Yusuf
- Yusuf
- Yusuf
- Yusuf
- Yusuf
- Yusuf
- Zeiher
- Zethelius
- Zhao
- Ziegelstein
- Publication venue
- Publication date
- 01/01/2012
- Field of study
The recommendations listed in this document are, whenever possible, evidence based. An extensive evidence review was conducted as the document was compiled through December 2008. Repeated literature searches were performed by the guideline development staff and writing committee members as new issues were considered. New clinical trials published in peer-reviewed journals and articles through December 2011 were also reviewed and incorporated when relevant. Furthermore, because of the extended development time period for this guideline, peer review comments indicated that the sections focused on imaging technologies required additional updating, which occurred during 2011. Therefore, the evidence review for the imaging sections includes published literature through December 2011
A SELECTIVE AND THEMATIC CHECKLIST OF PUBLICATIONS RELATING TO FRANCO - AMERICANS
- Author
- Adrian Patricia Wood
- Anon.
- Anon.
- Anon.
- Anon.
- Anon.
- Anon.
- Anon.
- Anon.
- Anon.
- Archambault Albéric
- Archambault Jacques
- Association Canado-Américaine.
- Auger Roland
- Beaulieu Victor-LĂ©vy
- Beno***it Josaphat
- Benoit Josaphat
- Bessette GĂ©rard
- Bilodeau Georges-Marie (abbé).
- Bonier Marie-Louise
- Boucher Georges-A.
- Boucher Georges-A.
- Boucher Georges-A.
- Bourbonnière Avila
- Bouvier Leon F.
- Brault GĂ©rard J.
- Brault GĂ©rard J.
- Brault GĂ©rard J.
- Brault GĂ©rard J.
- Brault GĂ©rard J.
- Brearly Katherine T.
- BĂ©langer Albert A.
- Carijolle Josette
- Carrière J.-M.
- Casanova Jacques-Donat
- Cather Willa
- Charters Ann
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chassé Paul-P.
- Chevalier Florence
- Corbett Edward M.
- Cormier Robert
- Cormier Robert
- Cormier Robert
- Costain Thomas B.
- Coulet du Gard René
- Crépeau Georges
- D'Amours Ernest-R.
- D'Amours Ernest-R.
- D'Amours Ernest-R.
- D'Amours Joseph-Arthur
- D'Arles Henri
- D'Arles Henri
- D'Arles Henri
- D'Arles Henri
- D'Arles Henri
- D'Arles Henri
- D'Arles Henri
- D'Arles Henri
- D'Arles Henri
- D'Arles Henri
- D'Arles Henri
- Dantin Louis
- Dantin Louis
- Dantin Louis
- Dantin Louis
- Dantin Louis
- Dantin Louis
- Dantin Louis
- Daoust Charles Roger
- Darbelnet Jean-Louis
- Deaulniers G. L.
- Dion-LĂ©vesque Rosaire
- Dion-LĂ©vesque Rosaire
- Dion-LĂ©vesque Rosaire
- Dion-LĂ©vesque Rosaire
- Dion-LĂ©vesque Rosaire
- Dion-LĂ©vesque Rosaire
- Dion-LĂ©vesque Rosaire
- Dion-LĂ©vesque Rosaire
- Dubay Guy
- Dubé Normand
- Ducharme Jacques
- Dufault Paul
- Duharme Jacques
- Dumaine Paul R.
- Dumas Emma
- Duval-Thibault Anna-Marie
- Duval-Thibault Anna-Marie
- Farley-Lamarche/Boréal Express
- Favreau Joseph-Arthur
- Fecteau Edouard
- Fecteau Edouard
- Fecteau Edouard
- Foley Allen B.
- Forget Ulysse
- Fortier Paul-J.
- French version
- Garff Dennis
- Garon Yves
- Gastonguay Alberte
- Gatineau FĂ©lix
- Gatineau FĂ©lix
- Girouard Joseph-Amédée.
- Gosselin Paul-E.
- Gosselin Paul-Emile
- Gosselin Paul-Emile
- Groulx Lionel
- Guertin Georges-Albert (Son Excellence)
- GĂ©lineau Louis-E. (Son Excellence).
- Habert Jacques
- Hamelin H.
- Hamelin Hormidas
- Hamon E. (S.J.).
- Jarvis Charles E.
- Jobin Antoine-J.
- Kennedy Ambrose
- Kerouac Jack
- Kerouac Jack
- Kerouac Jack
- Kloss Heinz
- Lagassé Julie de Champlain
- Laliberté Adélard
- Lambert Adélard
- Landry Thomas-M. (O.P.).
- LaPierre Laurier L.
- Lavallée Wilfrid N.
- Lemaire Hervé B.
- Lemelin Emile
- Lemieux Alice
- Lemieux-LĂ©vesque Alice
- Lemieux-LĂ©vesque Alice
- Lessard [Bissonnette] Camille
- Magnan Denis-Michel-Aristide
- Magnan Denis-Michel-Aristide
- McAndrew William J.
- McConnell Robert G.
- Metalious Grace
- Mollica Anthony
- Nadeau Gabriel
- Nadeau Gabriel
- Nadeau Gabriel
- Paris Robert L.
- Paris Robert L.
- Paris Robert L.
- Parsons Vivian Lajeunesse
- Pouliot Richard
- Pousland Edward
- Primeau Ernest-J. (Son Excellence).
- Prior Granville T.
- Rhéaume Gertrude
- Rioux Marcel
- Rioux Marcel
- Roberge CĂ©leste
- Robert Adolphe
- Robert Adolphe
- Robert Adolphe
- Robert Adolphe
- Robert Adolphe
- Robert Adolphe
- Robert Adolphe
- Robert Adolphe
- Robert Adolphe
- Robert Adolphe
- Robert Adolphe
- Robert Adolphe
- Robert Adolphe
- Robert Adolphe
- Robichaud GĂ©rard
- Rocheleau-Rouleau Corinne
- Rocheleau-Rouleau Corinne
- Roy Joseph-Hormidas
- Rumilly Robert
- Sage Doris
- Sainte-Marie Philippe
- Sansouci Lucien
- Santerre Richard
- Santerre Richard
- Schriver Edward
- Simano Irene
- Smyth James W.
- Therriault Soeur Mary-Carmel
- Tremblay RĂ©mi
- Tremblay RĂ©mi
- Tremblay RĂ©mi
- Tremblay RĂ©mi
- Tremblay RĂ©mi
- Tremblay RĂ©mi
- Tremblay RĂ©mi
- Trottier Maurice
- Trottier Maurice
- Trudel Marcel
- Truesdell LĂ©on
- Verrette Adrien
- Verrette Adrien
- Verrette Adrien
- Verrette Adrien
- Verrette Adrien
- Verrette Adrien
- Verrette Adrien
- Verrette Adrien
- Verrette Adrien
- Verrette Adrien
- Verrette Adrien
- Viatte Auguste
- Viau Eusèbe
- Violette Maurice
- Wade Mason
- Wade Mason
- Wade Mason
- Walker David
- Wessel Bessie B.
- Wilson Bruno
- Winks Robin W.
- Wright Davidson Carroll
- Zoltvany Yves F.
- Publication venue
- 'Liverpool University Press'
- Publication date
- Field of study
2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery
- Author
- Aaberge
- Aaberge
- Abbaszadeh
- Abboud
- Abizaid
- Aboyans
- Abraham
- Abramov
- Acar
- Adabag
- Ades
- Adolph M. Hutter
- Agarwal
- Aklog
- Al Suwaidi
- Al-Khatib
- Al-Sarraf
- Alderman
- Alexander
- Alexander
- Alexander
- Alexander
- Alexiou
- Alghamdi
- Ali
- Allen
- Allen
- Alserius
- Amar
- Amin
- Amoroso
- Anand
- Anderson
- Anderson
- Andersson
- Andreasen
- Andrew
- Andrews
- Angelini
- Angelini
- Angouras
- Anthonisen
- Antman
- Arabaci
- Argenta
- Argenziano
- Ariano
- Armitage
- Aronson
- Arora
- Ascione
- Athanasiou
- Augoustides
- Austin
- Austin
- Autschbach
- Avidan
- Avidan
- Aziz
- Badreldin
- Bae
- Baigent
- Baigent
- Baillot
- Bainbridge
- Bainbridge
- Bair
- Balacumaraswami
- Banbury
- Banning
- Bapoje
- Barakate
- Bardakci
- Barner
- Barner
- Barner
- Basso
- Becker
- Bell
- Beller
- Ben-Gal
- Benedetto
- Benedetto
- Bennett
- Bennett-Guerrero
- Benzer
- Berendes
- Berger
- Berger
- Berger
- Bergquist
- Berkowitz
- Bernard
- Berntsen
- Berridge
- Berry
- Biancari
- Bignami
- Bijker
- Bilgin
- Bilgin
- Bingol
- Biondi-Zoccai
- Birkmeyer
- Birkmeyer
- Birkmeyer
- Birkmeyer
- Birkmeyer
- Birkmeyer
- Birkmeyer
- Birkmeyer
- Birkmeyer
- Birkmeyer
- Bizzarri
- Bjork
- Blanchard
- Blankstein
- Blumberg
- Blumenthal
- Boden
- Bolon
- Bonaros
- Bonaros
- Bonaros
- Bonatti
- Bonatti
- Bonow
- Boodhwani
- Borger
- Borger van der Burg
- Borowicz
- Boudriot
- Bourassa
- Bourassa
- Boylan
- Brady
- Brandrup-Wognsen
- Bratzler
- Braunwald
- Bravata
- Braxton
- Breisblatt
- Brener
- Brener
- Brener
- Brennan
- Bridges
- Briguori
- Brooks
- Brophy
- Brown
- Bucerius
- Bucerius
- Buche
- Bucher
- Buckberg
- Budeus
- Bukkapatnam
- Bundy
- Burkhoff
- Buszman
- Butterworth
- Butterworth
- Bybee
- Cahalan
- Cai
- Caimmi
- Cameron
- Cannon
- Cannon
- Canver
- Caplan
- Capodanno
- Caracciolo
- Carey
- Carrie
- Cartier
- Cashin
- Castellheim
- Cavender
- Cecil
- Chaitman
- Chaitman
- Chakravarty
- Chamchad
- Chan
- Chaney
- Chang
- Charles R. Bridges
- Charrot
- Chassin
- Chatterjee
- Cheitlin
- Cheitlin
- Chelemer
- Chen
- Chen
- Cheng
- Cheng
- Cheng
- Chertow
- Chesebro
- Chesebro
- Cheung
- Chevalier
- Chieffo
- Chieffo
- Chieffo
- Chiu
- Choudhry
- Chowdhury
- Christakis
- Christenson
- Christenson
- Christenson
- Christenson
- Christenson
- Christenson
- Christiansen
- Chu
- Chukwuemeka
- Chung
- Cisowski
- Cisowski
- Clark
- Clark
- Clark
- Cogliati
- Cole
- Coleman
- Collard
- Conaway
- Connerney
- Connolly
- Cook
- Cooper
- Corrado
- Coskun
- Cowan
- Crabtree
- Craver
- Creswell
- Crystal
- Cywinski
- Czech
- Czerny
- D'Ambra
- Dacey
- Danner
- Daoud
- Daoud
- David M. Shahian
- Davies
- Davies
- Davis
- Davis
- Davis
- Davison
- De Hert
- De Hert
- De Hert
- de Leval
- De Paulis
- DeBois
- DeFoe
- Del Duca
- Dempsey
- Desai
- Despotis
- DeWood
- Di Carli
- Di Mauro
- Di Mauro
- Dial
- Diegeler
- Djaiani
- Dodds Ashley
- Doenst
- Donatelli
- Doss
- Dotani
- Dowd
- Dranove
- Drenth
- Drenth
- Drew
- Dudley
- Duncan
- Durand
- Dyke
- Dyub
- Dzavik
- Dzavik
- Eagle
- Ebrahimi
- Echahidi
- Edmonds
- Edmonds
- Edwards
- Eefting
- Eifert
- Eisenstein
- Eisenstein
- Ekery
- El-Hamamsy
- Ellen C. Keeley
- Ellis
- Eltzschig
- Engblom
- Englberger
- Engoren
- Ennker
- Ennker
- Erickson
- Evans
- Every
- Fansa
- Farkouh
- Fattouch
- Fattouch
- Favarato
- Faxon
- Fearn
- Fedoruk
- Feit
- Fekety
- Ferguson
- Ferguson
- Ferguson
- Fergusson
- Ferraris
- Ferraris
- Ferraris
- Ferraris
- Ferraris
- Ferraris
- Filizcan
- Fillinger
- Filsoufi
- Filsoufi
- Filsoufi
- Filsoufi
- Filsoufi
- Finkelstein
- Fiore
- Firanescu
- Fischer
- FitzGibbon
- FitzGibbon
- FitzGibbon
- Fleck
- Fleck
- Fleisher
- Fletcher
- Flood
- Fong
- Fontes
- Fortescue
- Fox
- Fox
- Fox
- Fox
- Fox
- Fox
- Frassdorf
- Frasure-Smith
- Fraund
- Frazier
- Freedland
- Friedman
- Friedrich
- Frommelt
- Frutkin
- Frye
- Fuller
- Furnary
- Furnary
- Furnary
- Fuster
- Fuster
- Fuster
- Fuster
- Galbut
- Gallagher
- Gandhi
- Gandhi
- Gani
- Gansera
- Gansera
- Garcia
- Gaudiani
- Geelhoed
- Geha
- Gengo
- Geraci
- Geyer
- Ghali
- Ghanta
- Ghorbel
- Ghosh
- Gibbons
- Gilard
- Gillinov
- Gillinov
- Gioia
- Glas
- Glineur
- Gold
- Goldenberg
- Goldman
- Goldman
- Goldstein
- Gombotz
- Goodman
- Gordon
- Goto
- Goto
- Gottesman
- Gottesman
- Goy
- Goy
- Goy
- Goy
- Goyal
- Goyal
- Graves
- Green
- Greilich
- Grigg
- Grines
- Groesdonk
- Grondin
- Groom
- Grover
- Grover
- Grover
- Grover
- Grumbach
- Grundy
- Gummert
- Gurbel
- Gurbuz
- Gurfinkel
- Gurne
- Guru
- Guru
- Guru
- Haase
- Hachamovitch
- Haeffener
- Hake
- Halkos
- Halm
- Halm
- Halonen
- Hambrecht
- Hamm
- Hammar
- Hammermeister
- Hammermeister
- Hangler
- Hannan
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- Hannan
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- Hannan
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- Hannan
- Hannan
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- Harker
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- Harrington
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- Hausenloy
- Hawkes
- Hayashi
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- Hedges
- Held
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- Hemmerling
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- Henry
- Heringlake
- Herman
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- Heusch
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- Hibbard
- Hibbard
- Hibbard
- Hibbard
- Hibbard
- Hilleman
- Hirai
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- Hlatky
- Hlatky
- Ho
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- Hochman
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- Hueb
- Hueb
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- Hughes
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- Iezzoni
- Ingels
- Ip-Yam
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- Ivert
- Ix
- Jacka
- Jacobs
- Jaffery
- Jain
- Javaid
- Jeffrey C. Trost
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- Jenkins
- Jenkins
- Jensen
- Jensen
- Jha
- Joaquin E. Cigarroa
- John A. Bittl
- John D. Puskas
- John G. Byrne
- Johnson
- Johnson
- Johnson
- Jones
- Jones
- Jones
- Jones
- Jones
- Jones
- Jones
- Jorenby
- Joseph F. Sabik
- Julier
- Jurkiewicz
- Kachroo
- Kaiser
- Kaiser
- Kaiser
- Kalant
- Kallis
- Kallmeyer
- Kamohara
- Kapetanakis
- Kapoor
- Kappetein
- Kapur
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- Khanna
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- Kim
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- King
- King
- Kirdemir
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- Ko
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- Landoni
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- London
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- Loop
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- Mangano
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- Mangano
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- Mukamel
- Mukamel
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- Murkin
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- Murphy
- Murphy
- Murphy
- Murphy
- Murphy
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- Myers
- Myles
- Myles
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- Normand
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- Pearson
- Pearson
- Peart
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- Peter K. Smith
- Peterson
- Peterson
- Peterson
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- Piper
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- Pocock
- Pocock
- Podesser
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- Pohl
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- Purcaro
- Puskas
- Puskas
- Puskas
- Puskas
- Puskas
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- Rabi
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- Rahimi
- Rahimi
- Rahman
- Raja
- Raja
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- Ranucci
- Ranucci
- Ranucci
- Rasmussen
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- Ray
- Raymond
- Reddan
- Reeves
- Reeves
- Regragui
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- Reiz
- Renda
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- Richard A. Lange
- Ridderstolpe
- Rigatelli
- Rigotti
- Rigotti
- Rinder
- Risnes
- Risum
- Roach
- Roberts
- Roberts
- Rodes-Cabau
- Rodondi
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- Rodriguez
- Rodriguez
- Rodriguez
- Roger
- Rollman
- Rollman
- Romano
- Romano
- Rosenberger
- Rosengart
- Rosengart
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- Rouleau
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- Roy
- Royse
- Royse
- Royston
- Rubens
- Ruberman
- Rudolph
- Rudolph
- Rudolph
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- Sabik
- Sabik
- Sabik
- Sabik
- Sabik
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- Saginur
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- Salehi
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- Sarma
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- Savage
- Savage
- Sawada
- Schachner
- Schauffler
- Schmoeckel
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- Schofield
- Schomig
- Schurr
- Schwann
- Scott
- Sedlis
- Seki
- Selim
- Selker
- Sellke
- Selnes
- Selnes
- Selnes
- Selnes
- Serfontein
- Sergeant
- Sergeant
- Serrano
- Serruys
- Serruys
- Serruys
- Sethi
- Seung
- Shahian
- Shahian
- Shahian
- Shahian
- Shahian
- Shahian
- Shahian
- Shahian
- Shahian
- Shahian
- Shahian
- Shahian
- Shamshad
- Shanewise
- Sharma
- Sharoni
- Sharony
- Shaw
- Sheiman
- Shernan
- Shim
- Shimizu
- Shimizu
- Shiran
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- Shroyer
- Silverman
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- Simons
- Simoons
- Sims
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- Singh
- Sirivella
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- Sjogren
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- Sjogren
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- Skubas
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- Slogoff
- Slogoff
- Smith
- Smith
- Smith
- Smith
- Smith
- Smith
- Smith
- Song
- Sorajja
- Sowade
- Sowden
- Spelman
- Spiegelhalter
- Spiegelhalter
- Srinivasan
- Stahle
- Stamou
- Stamou
- Starobin
- Staton
- Stein
- Stephan
- Stephen J. Lahey
- Stevens
- Stewart
- Stone
- Straka
- Stroupe
- Stygall
- Subramanian
- Sukernik
- Suma
- Sun
- Surgenor
- Suvarna
- Svensson
- Svircevic
- Swaminathan
- Swaminathan
- Sweet
- Sylivris
- Szczech
- Szczech
- Tabata
- Taghaddomi
- Taillefer
- Takagi
- Takaro
- Takaro
- Talley
- Tamburino
- Tanaka
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- Tarakji
- Tarakji
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- Taylor
- Taylor
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- Thiele
- Thiele
- Thielmann
- Thielmann
- Thielmann
- Thiene
- Thomas
- Thomas
- Thygesen
- Thys
- Ting
- Tonino
- Tonino
- Toor
- Toumpoulis
- Townsend
- Trichon
- Trikalinos
- Tsuyuki
- Tu
- Tully
- Tuman
- Tumlin
- Turer
- Turner
- Tyras
- Urbach
- Urban
- Utley
- Vaccarino
- van
- van de Watering
- van den Berghe
- van der Linden
- van Dijk
- van Domburg
- van Domburg
- van Eck
- van Mastrigt
- van Mastrigt
- van Mastrigt
- van Rijen
- van Straten
- van Straten
- Varani
- Varnauskas
- Vassiliades
- Vassiliades
- Veeger
- Velazquez
- Veliz-Reissmuller
- Venge
- Venugopal
- Verdi J. DiSesa
- Vesely
- Vincent
- Vineberg
- Vlietstra
- von Segesser
- Voors
- Vuorisalo
- Wadhera
- Wahrborg
- Walpoth
- Walsh
- Walsh
- Walsh
- Walsh
- Walther
- Wang
- Wang
- Wang
- Wang
- Wasvary
- Watanabe
- Webb
- Weightman
- Weiner
- Weintraub
- Weintraub
- Weintraub
- Weiss
- Welke
- Welke
- Welsby
- Weltert
- Wenger
- Werdan
- Werner
- White
- White
- White
- Wiesbauer
- Wijeysundera
- Wijns
- Williams
- Wilson
- Wiviott
- Wong
- Wong
- Wright
- Wu
- Wu
- Xia
- Yamaguchi
- Yang
- Yang
- Yao
- Yap
- Yau
- Yellon
- Yende
- Yeung-Lai-Wah
- Yli-Mayry
- Young
- Yu
- Yusuf
- Yusuf
- Zanardo
- Zarbock
- Zhao
- Zimarino
- Zingone
- Zoghbi
- Zvara
- Publication venue
- 'Elsevier BV'
- Publication date
- 06/12/2011
- Field of study
Rationale, design, and baseline characteristics in Evaluation of LIXisenatide in Acute Coronary Syndrome, a long-term cardiovascular end point trial of lixisenatide versus placebo
- Author
- Abid Mohamed
- Accini Jose Luis
- Acuña Silvia
- Adawi Faiad
- Adenuga Babafemi
- Adina Pop-Moldovan
- Ageev Fail
- Aguilar David
- Aguilar-Orozco Raul
- Ahmad Zia
- Aimaretti Gianluca
- Aizenberg Diego
- Akahori Hiroshi
- Akhmedzhanov Nadir
- Akinboboye Olakunle
- Akright Laura
- Al Mahmeed Wael
- Alanko Juha
- Alappat Paul
- Alawad Mohamad
- Alfonso Teresa
- Alimard Ramin
- Allen Peter
- Alvarez Carlos
- Alvarisqueta Andres
- Alzohaili Opada
- Ambos Anu
- Amerena John
- Amolina Ildze
- Andjelic Jelic Marina
- Andrade Miguel
- Andrews Robert
- Antorrena Isabel
- Araneda Guillermo
- Arango Juan
- Ariani Mehrdad
- Arnold Susan
- Arora Chander
- Arteaga Juan Manuel
- Assaad Samir
- Atar Shaul
- Avram Rodica Ioana
- Azad Nasrin
- Azzam Samir
- Baccaro Claudia
- Bailey Gordon
- Bain Stephen
- Barbarash Olga
- Barbarich Vladimir
- Barkoudah Ebrahim
- Bartolacci Ines
- Bascil Tutuncu Neslihan
- Basu Ambar
- Bayram Edmundo
- Bednarski Janusz
- Belousov Yury
- Ben Abdallah Nejib
- Benjamin Sabrina
- Bentley-Lewis Rhonda
- Berns Svetlana
- Berra Cesare
- Bertrand Olivier
- Bhargava Rakesh
- Bhatnagar Deepak
- Bickerton Alex
- Bijata-Bronisz Renata
- Block Bradley
- Boberg Gunnar
- Bodi Vicent
- Bokarev Igor
- Bolshakova Olga
- Bordonava Anselmo
- Borzadek Eliza
- Botelho Roberto Vieira
- Botella Marta
- Botero Rodrigo
- Boyarkin Mikhail
- Bragança Nuno
- Brahimi Abdel
- Breisblatt Warren
- Bright Tamis
- Bronnum-Schou Jens
- Browne Duncan
- Bryniarski Leszek
- Bunster Lia
- Burgess Lesley
- Burton Jeffrey
- Bustamante Labarta Miguel
- Busz-Papiez Benita
- Byrd Leroy
- Caccavo Alberto
- Calderon Jorge
- Calella Pedro
- Campeau Jean
- Camsari Ahmet
- Cantero Maria
- Cardosa-Torres Francisco
- Cariou Bertrand
- Carranza-Madrigal Jaime
- Castillo Gilberto
- Castro Eholo
- Castro Maria Guadalupe
- Catargi Bogdan
- Cerqueira Maria Jose
- Chacra Antonio
- Charytan David
- Chaturvedi Nishi
- Chavez Carlos
- Chen Li
- Chiang Chern-En
- Chiou Choyen
- Chiu Yu-Wei
- Chochinov Ronald
- Chopda Manoj
- Chopra Vijay
- Christensen Tom
- Christofides Elena
- Chumakova Galina
- Chumburidze Vakhtang
- Chung Choon Hee
- Chung Wook Jin
- Ciardullo Anna Vittoria
- Cif Adriana
- Claggett Brian
- Cobos Leonardo
- Codutti Renzo
- Coetzee Kathleen
- Cohen Ohad
- Cohen Robert
- Commendatore Victor
- Consoli Agostino
- Contzen Christel
- Cooper John
- Corbalán Ramón
- Cornel Jan Hein
- Coronel Julian
- Correa Flores Roger Martin
- Costamagna Osvaldo
- Creteanu Gabriela
- Cucinotta Domenico
- Cuello Jose
- Cure Carlos
- Czajkowska-Kaczmarek Eugenia
- Danilova Larisa
- Dans Antonio
- Dawood Gamil
- Dawood Saleem
- De La Fuente Javier
- De Souza Jose
- Dekkers Paulus
- Del Prato Stefano
- Delchev Alexy
- Delgado ElĂas
- Delibasi Tuncay
- Delport Eluned
- DeMets David
- Dempsey Michael
- Deshpande Neeta
- Di Marco Sandra
- Diaz Rafael
- Dickstein Kenneth
- Dinccag Nevin
- Dmitry Platonov
- Dong Yugang
- Dos Santos Fabio
- Dragomir Dinu
- Drzewiecka Anna
- Du Jianling
- Duarte JoĂŁo
- Duarte-Vera Yan
- Ducena Kristine
- Ducloux Roxane
- Dulak Elzbieta
- Dumas Richard
- Duran Garcia Santiago
- Dussaillant Gaston
- Dutta R.
- Dwivedi Sudhanshu
- Eagerton Donald
- East Cara
- Ebrahim I.
- Efrati Shai
- Eggers German
- Eki Yutaka
- Elder Charles
- Ellis Graham
- Elorza Jose
- Enciso Fidel
- Escalante Miguel
- Farfan Julio
- Fasching Peter
- Feitosa Gilson
- Ferariu Ioana Emilia
- Fernandez Alberto
- Fernando Ronald
- Filteau Pierre
- Finn Peter
- Fischer Hermann
- Fitilev Sergey
- Florenzano Fernando
- Flynn Aiden
- Fogelfeld Leon
- Forti Adriana
- Foucauld Jean
- Frederiks J.
- French William
- Frohnauer Mary
- Fujii Kenshi
- Gaffney Mary
- Galeana Cielmar
- Galyavich Albert
- Gandhi Pramod
- Gangopadhyay Subroto
- Garcia Duran Ruben
- Garcia Henry
- Garcia Luis
- Garcia-Castillo Armando
- Garcia-Hernandez Pedro
- Garcia-Soria Martin
- Garza Jose
- Gaztambide Sonia
- Gerstein Hertzel C.
- Gibson Martin
- Giorda Carlo
- Giordano Carla
- Glezer Maria
- Glonti Salome
- Godoy Gonzalo
- Gogia Harinder
- Golbert Milton
- Gomez Vilamajo Oscar
- Gomez Claudia
- Gomez Maria Honolina
- Gonzalez Castillo Baldomero
- Gonzalez Elis
- Gonzalez Jose Gerardo
- Gonzalez Ronaldo
- Gorban De Lapertosa Silvia
- Gorska Maria
- Gosmanov Aidar
- Granados Arnoldo
- Granger Christopher
- Greenberg Craig
- Greenway Frank
- Grinfeld Diego
- Guo Xiaohui
- Gupta Jugal Bihari
- Gupta Sandeep Kumar
- Gupta Sunil
- Hadjadj Samy
- Hagenow Andreas
- Halpern Alfredo
- Hamankiewicz Maciej
- Hammond Peter
- Han Ping
- Hanna Edward
- Hanna Fahmy
- Haouala Habib
- Hargrove Joe
- Harris Anthony
- Harris Bill
- Hart Terence
- Hartley L. Howard
- Hata Yoshiki
- Hatterjee Sanjay
- Helda Renate
- Henderson Galen
- Hermans Wrm
- Hermida Sonia
- Hernandez Triana Eric
- Hernandez Hector
- Hernandez-Muñuzuri Jesus
- Herrera Milton
- Herrington David
- Hewitt Mitzie
- Himeno Hideo
- Himpel-Bönninghoff Agnes
- Hirayama Atsushi
- Hiregouder Narendra
- Hissa Miguel
- Howard David
- Hu Taohong
- Huang Tsuei-Yuan
- Huidobro Laura Andrea
- Iancu Adrian-Corneliu
- Ismail Siddique
- Issa Basil
- Istratoaie Octavian
- Ivanica Gabriel
- Ivanov Valentin
- Ivanova Luidmila
- Izuora Kenneth
- Jaap Alan
- Jakovlev Ulle
- Jang Hakchul
- Janik Krzysztof
- Jendle Johan
- Jetty Preetham
- Jha Sujeet
- Jiang Bin
- Jimenez Silvia
- Johnston Peter
- Joseph Franklin
- Joseph Jacob
- Joshi Abhijeet
- Jude Edward
- Jörneskog Gun
- Kaddaha Ghaida Mohamad
- Kaiser Nielsen Peter
- Kakariekiene Vaida
- Kalashnikov Victor
- Kalashnikova Marina
- Kaplan Allen
- Kapoor Anoop
- Karnieli Eddy
- Karpenko Oleksandr
- Karpov Yuri
- Kasper Joseph F.
- Kavaliauskiene Roma
- Ke Yuannan
- Kelbe Dudley
- Kelehan Shaun
- Kelly Chris
- Kelly Richard
- Kereiakes Dean
- Kerlan Veronique
- Khaira Ajit
- Khaisheva Larisa
- Khalimov Yuri
- Khan Atir
- Khan Misal
- Khan Noor
- Khan Salman
- Kihm Lars
- Killat Holger
- Kim Chong-Jin
- Kim Jaetaek
- Kim Kyehun
- Kim Ung
- Kincel Krzysztof
- Kishimoto Ichiro
- Klainman Eliezer
- Kleinertz Klaus
- Klyuchkova Neli
- Kobalava Zhanna
- Kobayashi Youichi
- Kocic Radivoj
- Komnenovic Snezana
- Konieczny Marek
- Konrade Ilze
- Korban Elie
- Korpachev Vadym
- Korsoff Pirkko
- Kosch Christine
- Kosiborod Mikhail
- Koski Anna-Mari
- Kosmachova Elena
- Kostenko Victor
- Koval Olena
- Koziolova Natalya
- Kreutzmann Kristin
- Kulibaba Elena
- Kultursay Hakan
- Kumbla Mukund
- Kyoleyan Michael
- Køber Lars V.
- Lagrutta Mariana
- Laguerre Jacques
- Lahsen Rodolfo
- Lahtela Jorma
- Lalic Katarina
- Lalic Nebojsa
- Lanas Fernando
- LappegĂĄrd Knut Tore
- Lappo Mariola
- Lara Susano
- Larenas Gladys
- Larocque James
- Latif Kashif
- Lawson Francesca
- Lee Nae Hee
- Leon De La Fuente Ricardo
- Lesnov Victor
- Lester Frank
- Levin Philip
- Levine Steven
- Levterov Georgi
- Lewis Eldrin F.
- Li Charles
- Li Zhanquan
- Libov Igor
- Licheri Alberto
- Lichiardopol Radu
- Lieberman Phil
- Lisboa Hugo
- Llamas Guillermo
- Lok Dirk
- Lominadze Zaza
- Lonso Elena
- Lopez Rosas Enrique
- Lopez Gabriel Arturo
- Lopez Monica
- Lopez Patricio
- Lovell Charles
- Lu Chieh-Hsiang
- Lu Juming
- Lu Libia
- Lubi Maire
- Lubinski Andrzej
- Lucheva Mariya
- Luciardi Hector
- Lujan Jesus
- Lupovitch Steven
- Luque Edith
- Lyamina Nadezhda
- Ma Changsheng
- Mackinnon Ignacio
- Madu Ivy-Joan
- Maffei Laura
- Magdum Mohan
- Maggioni Aldo P.
- Mahabadi Vahid
- Mahmood Asif
- Malecot Jean-Marc
- Malik Rayaz
- Mannucci Edoardo
- Manrique Helard
- Manriquez Leopoldo
- Manzur Fernando
- Maragos Stavros
- Marck Cornelia
- Mariash Cary
- Marin Francisco
- Marino Javier
- Markov Valentin
- Marmol Alvear Ricardo
- Martin Paul
- Martin Victoria
- Maslyanko Vitaliy
- Mathew James
- Mathew John
- Mathiesen Ulrik
- Mathieu Chantal
- Mauricio Didac
- May Michael
- Mayfield Ronald
- McCall Anthony
- Mcdaniel Clayton
- Mcgrew Frank
- Mckenzie Marcus
- McMurray John J. V.
- Medina Marcelo
- Meeder Joan
- Mefford Ivan
- Mehta Arvind
- Mertes Bernardo
- Micic Dragan
- Mikdadi Ghiath
- Mikhail Magdy
- Militaru Constantin
- Minescu Bogdan
- Minuchin Oscar
- Mitkovskaya Natalya
- Miyaoka Hiroaki
- Moccetti Tiziano
- Mogrovejo Walter
- Moiseev Valentin
- Molchanova Olga
- Molina Dora
- Monchamp Travis
- Montaña Oscar
- Monteiro Pedro
- Montenegro Pablo
- Moore Charles
- Moraes Joao
- Moran Michael
- Morrar Nidal
- Mosenzon Ofri
- Mosley Jonathan
- Mukhopadhyay Babu
- Mulford Mim
- Munoz Ricardo
- Murray John
- Murthy Keshava
- Märtsin Kaja
- Naidoo Visvakuren
- Nakhle Samer
- Nallasivan Mani
- Nedrebø Bjørn Gunnar
- Nelimarkka Lassi
- Nery Max
- Nielsen Henrik
- Nierop Peter
- Nieto Ortega Ruben
- Niiya Tetsuji
- Nishi Yutaro
- Novaretto Leonardo
- Nozaki Akira
- Ntsekhe Mpiko
- Nunohiro Tatsuya
- O'Kane M.
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- Stern Naftali
- Stobschinski De Alba Carlos Alejandro
- Stryuk Raisa
- Su Guohai
- Sudzhaeva Svetlana
- Sulit Dennis Jose
- Supe Pravin
- Suplotova Ludmila
- Suresh Damodhar
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- Sy Rosa Allyn
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- Syan Rajinder
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- Vazquez-Garcia Abraham
- Velasco-Sanchez Raul
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- Vico Marisa
- Vida Manuel
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- Vidrio Maricela
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- Villalobos Renato
- Vinereanu Dragos
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- Vishnevsky Alexander
- Vorokhobina Natalia
- Wainstein Julio
- Waisman Florencia
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- Warner Alberta
- Warnica James Wayne
- Watanabe Shuichi
- Watson Henry
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- Webster Brian
- Weindorff Kathleen
- Weinrauch Larry
- Welch Michelle
- Welker James
- Westerberg Bernhard
- White Anthony
- White Lindsey
- Whitelaw Donald
- Wilczewski Przemyslaw
- Wilding John
- Wiles Philip
- Williams Marcus
- Wu Wen-Chih
- Wu Yujun
- Wynne Alan
- Wyss Fernando
- Xu Biao
- Yakusevich Vladimir
- Yakushin Sergey
- Yamada Takahisa
- Yang Jiefu
- Yang Jinkui
- Yang Yanmin
- Yañez Mario
- Yeap Bu
- Yigit Zerrin
- Yocono Mark
- Yordanov Viktor
- Yuen Kevin
- Yupanqui Hernan
- Zadionchenko Vladimir
- Zalevskaya Alsu
- Zalevsky Grigory
- Zarankiene Rima
- Zateyshchikova Anna
- Zavala Alejandro
- Zhuravleva Larisa
- Zidi Borni
- Zorkun Cafer
- Zubiate Carlos
- Zuraw Bruce L.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2015
- Field of study
BACKGROUND:
Cardiovascular (CV) disease is the leading cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Furthermore, patients with T2DM and acute coronary syndrome (ACS) have a particularly high risk of CV events. The glucagon-like peptide 1 receptor agonist, lixisenatide, improves glycemia, but its effects on CV events have not been thoroughly evaluated.
METHODS:
ELIXA (www.clinicaltrials.gov no. NCT01147250) is a randomized, double-blind, placebo-controlled, parallel-group, multicenter study of lixisenatide in patients with T2DM and a recent ACS event. The primary aim is to evaluate the effects of lixisenatide on CV morbidity and mortality in a population at high CV risk. The primary efficacy end point is a composite of time to CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for unstable angina. Data are systematically collected for safety outcomes, including hypoglycemia, pancreatitis, and malignancy.
RESULTS:
Enrollment began in July 2010 and ended in August 2013; 6,068 patients from 49 countries were randomized. Of these, 69% are men and 75% are white; at baseline, the mean ± SD age was 60.3 ± 9.7 years, body mass index was 30.2 ± 5.7 kg/m(2), and duration of T2DM was 9.3 ± 8.2 years. The qualifying ACS was a myocardial infarction in 83% and unstable angina in 17%. The study will continue until the positive adjudication of the protocol-specified number of primary CV events.
CONCLUSION:
ELIXA will be the first trial to report the safety and efficacy of a glucagon-like peptide 1 receptor agonist in people with T2DM and high CV event risk
Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes
- Author
- Abayomi Osunkoya
- Abderrahim Oulhaj
- Abraham Salacata
- Adam DeVore
- Adi Butnaru
- Aditya Mandawat
- Adolphus Anekwe
- Adriaan Kooy
- Adrian Cruciani
- Adrian Schnall
- Adriana Costa e Forti
- Adriana Philippiova
- Adriana Villarino
- Adriano Truffa
- Agatha Wilhase
- Agnes-Anette Himpel Boenninghoff
- Ajay Labroo
- Alain Taylon
- Alan Bell
- Alan Forker
- Alan Kravitz
- Alan Marcus
- Alan Tannenbaum
- Alan Wine
- Albert Lecube
- Albert LeCube Torello
- Alejandro Orozco Linares
- Alessandro Cavarape
- Alessandro Salvioni
- Alexander Dreval
- Alexander Higgins
- Alexander Khokhlov
- Alexander Sherenkov
- Alexander Tong-Boon Tan
- Alexander V Dreval
- Alexey Repin
- Alfonso Soto
- Alice Pik Shan Kong
- Alison Dawson
- Allegra Stone
- Allen Greenspoon
- Amanda Adler
- Amir Bashkin
- Amorin Remus Popa
- Amrit Takhar
- Amritanshu Pandey
- Ana Zazula
- Anand Rohatgi
- Anat Jaffe
- Andras Nagy
- Andras Papp
- Andras Taller
- Andrea Ferch
- Andrea Mölle
- Andrea On Yan Luk
- Andrea Tisch
- Andreas Hamann
- Andreas Mugge
- Andreas Pfutzner
- Andrej Dzupina
- Andrej Levinger
- Andrew Hamer
- Andrew Johnson
- Andrew McWilliams
- Andrew Woodall
- Andrey Obrezan
- Andrian Yakov
- Andrés Alvarisqueta
- Ann Verhaegen
- Anna Chang
- Anna Grabowska
- Anna Mikolajczyk-Swatko
- Anne Chang
- Anne Kilvert
- Anne Milward
- Anthony Bartkowiak Jr
- Anthony Vo
- Anthony White
- Anthony Wright
- Anton Luger
- Antonio Chacra
- Anuj Bhargava
- Araceli Panelo
- Aranka Kovacs
- Arthur Jimenez
- Arvind Cavale
- Asha Thomas
- Asma Khan
- Attila Palinkas
- Audrone Augusteniene
- Audrone Velaviciene
- Axel Akerblom
- Axel Schaefer
- Aysha Badat
- B van Bemmel
- Bankim Bhatt
- Barbara Cylkowska
- Barry Reicher
- Basil Akpunonu
- Basil Lewis
- Benito Garbelini
- Benjamin Field
- Berhane Seyoum
- Bernard Erickson
- Bernard Man-Yeung Cheung
- Bernd Becker
- Bernhard Landers
- Bernhard Paulweber
- Bethel M. A.
- Bimal Shah
- Blandine Laferrere
- Boguslaw Okopien
- Brian Katona
- Brian Schactman
- Brian Short
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- Bruce Jackson
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- Bryan Ping Yen Yan
- Buse J. B.
- Byung-Hee Oh
- Candice Delcourt
- Carlo Maria Rotella
- Carlos Alberto Cure Cure
- Carlos Alexandre Almeida
- Carlos Arauz-Pacheco
- Carlos Jaramilo
- Carlos Jose Jaramilo Gomez
- Carlos Raffo
- Carol Wysham
- Carolina Gonzaga
- Caryn Baldauf
- Catalina Rua Marin
- Catherine Bain
- Cecelia Jimeno
- Cedrice Davis
- Cesar Zaidman
- Cezar Staniloae
- Chaitanya Ravi
- Chan J. C.
- Chang-Wook Nam
- Changsheng Ma
- Chantal Mathieu
- Chanyu Pan
- Charles Bundy
- Charles Eaton
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- Cheryl Louw
- Chetan Patel
- Chhavi Chadha
- Chiara Melloni
- Chih-Yuan Wang
- Chiu-Chi Tsang
- Choi J.
- Chong Dang
- Chong-Jin Kim
- Chris Sorli
- Christine Voors-Pette
- Christoph Ebenbichler
- Christoph Schnack
- Chwen-Yi Yang
- Claudia Francesconi
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- Colin Helm
- Connie Hess
- Constantin Mlitaru
- Curtis Campbell
- Dace Teterovska
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- Dalibor Sosovec
- Damodhar Suresh
- Dan Larson
- Dana Headapohl
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- Daniel Weiss
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- Darren McGuire
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- Yee-Weng Wong
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- Yi-Jen Hung
- Yiming Mu
- Yingqing Feng
- Ynez Kelfkens
- Yolanda Meadows
- Yong Wang
- Yoon-Nyun Kim
- Youping Dong
- Yulia Samoylova
- Yuming Du
- Yupin Benjasuratwong
- Yves Robitaille
- Zahari Nikitov
- Ziad Gellad
- Zinaida Teliatnikova
- Zinman B.
- Zoltan Czegany
- Zsolt Gaal
- Zsolt Pauker
- Zsolt Ples
- Zsolt Zilahi
- Zsuzsanna Kerenyi
- Zubin Eapen
- Zubin Punthakee
- Zuyi Yuan
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2017
- Field of study
BACKGROUND: The cardiovascular effects of adding once-weekly treatment with exenatide to usual care in patients with type 2 diabetes are unknown. METHODS: We randomly assigned patients with type 2 diabetes, with or without previous cardiovascular disease, to receive subcutaneous injections of extended-release exenatide at a dose of 2 mg or matching placebo once weekly. The primary composite outcome was the first occurrence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke. The coprimary hypotheses were that exenatide, administered once weekly, would be noninferior to placebo with respect to safety and superior to placebo with respect to efficacy. RESULTS: In all, 14,752 patients (of whom 10,782 [73.1%] had previous cardiovascular disease) were followed for a median of 3.2 years (interquartile range, 2.2 to 4.4). A primary composite outcome event occurred in 839 of 7356 patients (11.4%; 3.7 events per 100 person-years) in the exenatide group and in 905 of 7396 patients (12.2%; 4.0 events per 100 person-years) in the placebo group (hazard ratio, 0.91; 95% confidence interval [CI], 0.83 to 1.00), with the intention-to-treat analysis indicating that exenatide, administered once weekly, was noninferior to placebo with respect to safety (P<0.001 for noninferiority) but was not superior to placebo with respect to efficacy (P=0.06 for superiority). The rates of death from cardiovascular causes, fatal or nonfatal myocardial infarction, fatal or nonfatal stroke, hospitalization for heart failure, and hospitalization for acute coronary syndrome, and the incidence of acute pancreatitis, pancreatic cancer, medullary thyroid carcinoma, and serious adverse events did not differ significantly between the two groups. CONCLUSIONS: Among patients with type 2 diabetes with or without previous cardiovascular disease, the incidence of major adverse cardiovascular events did not differ significantly between patients who received exenatide and those who received placebo
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- Publication venue
- 'Walter de Gruyter GmbH'
- Publication date
- 01/01/1940
- Field of study
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease
- Author
- Aaberge
- Abdelmoneim
- Abernethy
- Abidov
- Abizaid
- Abrams
- Abrams
- Agatston
- Agelink
- Akhtar
- Akram
- Al Suwaidi
- Al-Mallah
- Alan L. Hinderliter
- Albert
- Alderman
- Alderman
- Alderman
- Alderman
- Alexander
- Allen
- Allen
- Allen
- Alter
- Ambrose
- America
- America
- Amin
- Anand
- Anavekar
- Anderson
- Angelini
- Antman
- Antman
- Antman
- Antman
- Apostolos P. Dallas
- Appel
- Appel
- Appel
- Appel
- Arnesen
- Arnlov
- Arnold
- Arnold
- Arora
- Artinian
- Aubry
- Avendano
- Avezum
- Azevedo
- Aziz
- Badran
- Bae
- Baigent
- Balady
- Ballegaard
- Ballegaard
- Balsano
- Bandura
- Bangalore
- Banning
- Barsness
- Bateman
- Baumhakel
- Bazzano
- Beckett
- Bell
- Bello
- Beltrame
- Ben-Gal
- Benedetto
- Beniamini
- Benzer
- Berger
- Berkman
- Berman
- Berman
- Berman
- Berman
- Bernheim
- Bernstein
- Berrington de Gonzalez
- Berrington de Gonzalez
- Bhatt
- Bhatt
- Bhatt
- Bhatt
- Biagini
- Bingham
- Biondi-Zoccai
- Bjelakovic
- Bjork Ingul
- Blankstein
- Blendea
- Block
- Blomkalns
- Blumenthal
- Boberg
- Boden
- Bodi
- Boekholdt
- Bogers
- Bohlen
- Boman
- Bonaa
- Bonaros
- Bonatti
- Bonnet
- Bonow
- Bonow
- Bonow
- Borer
- Borger van der Burg
- Borjesson
- Bosworth
- Bottcher
- Boudriot
- Bourassa
- Bouzas-Mosquera
- Bouzas-Mosquera
- Bozzette
- Braunwald
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- Cecil
- Cecil
- Cerqueira
- Chaitman
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- Chaitman
- Chaitman
- Chakravarty
- Chan
- Chaowalit
- Charatan
- Chatterjee
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- Cheezum
- Cheitlin
- Chen
- Cheng
- Cheng
- Chieffo
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- Dey
- Dey
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- Elveback
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- Emond
- Epstein
- Every
- Ezekowitz
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- Feit
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- Feuchtner
- Fiechter
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- Fleischmann
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- Ford
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- Fox
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- Fox
- Fraker
- Frank
- Franklin
- Franzen
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- Fraund
- Frazier
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- Freemantle
- Friis-Moller
- Frishman
- Frishman
- Froelicher
- Frosch
- Fryback
- Frye
- Fukushima
- Gaede
- Galinanes
- Garber
- Garg
- Gebker
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- Gehi
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- George
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- Gerstein
- Getz
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- Gibbons
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- Gil
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- Gilard
- Gimelli
- Ginsberg
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- Glynn
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- Gordon
- Gori
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- Gorin
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- Gottlieb
- Goy
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- Grady
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- Greenfield
- Greenland
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- Grimm
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- Gruberg
- Grundy
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- Gu
- Guadagnoli
- Gulati
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- Gupta
- Gurfinkel
- Gurm
- Haberl
- Hachamovitch
- Hachamovitch
- Hachamovitch
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- Hachamovitch
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- Hachamovitch
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- Hachamovitch
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- Hacker
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- Halliburton
- Hallikainen
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- Hambrecht
- Hambrecht
- Hamdan
- Hamm
- Hammermeister
- Hamon
- Hamon
- Hamon
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- Hannan
- Hannan
- Harlan M. Krumholz
- Harris
- Hashimoto
- Haskell
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- Hauf-Zachariou
- Hautvast
- Hautvast
- He
- Hebert
- Heidenreich
- Heitzer
- Held
- Helton
- Hemingway
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- Henderson
- Henneman
- Herzog
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- Hillis
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- Hlatky
- Hlatky
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- Ho
- Ho
- Ho
- Hochholzer
- Hoffman
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- Holman
- Holmboe
- Holmes
- Holubkov
- Holzhey
- Homcy
- Hong
- Hong
- Honig
- Horne
- Hosokawa
- Hsieh
- Hubbard
- Hueb
- Hueb
- Hueb
- Hueb
- Hughes
- Hughes
- Hulley
- Hundley
- Hunt
- Iafrate
- Imran
- Ingkanisorn
- Innocenti
- Ishikawa
- Isner
- Ix
- Jacobs
- Jacobs
- Jaffery
- Jagathesan
- Jahnke
- James C. Blankenship
- Jane A. Linderbaum
- Janne d'Othee
- Janosi
- Javaid
- Javitz
- Jensen
- Jerling
- Jneid
- Jneid
- Joanna D. Sikkema
- JoAnne M. Foody
- Joannides
- Johansen
- John A. Spertus
- Johnson
- Johnson
- Jonathan Abrams
- Jones
- Jones
- Jones
- Jones
- Jorenby
- Joseph F. Sabik
- Jouven
- Julius
- Julius M. Gardin
- Jurca
- Juul-Moller
- Juurlink
- Kaiser
- Kamalesh
- Kang
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- Spertus
- Spertus
- Staessen
- Stamler
- Stamler
- Stamou
- Stampfer
- Stampfer
- Stampfer
- Stead
- Stead
- Steel
- Stein
- Steinhubl
- Stephan
- Stephan D. Fihn
- Stephens
- Stevens
- Stevens
- Stone
- Stone
- Stratmann
- Stroupe
- Stys
- Subramanian
- Sullivan
- Sun
- Sun
- Szczech
- Tabib
- Taillefer
- Takaro
- Takaro
- Tamaki
- Tamburino
- Tan
- Tanaka
- Tandogan
- Tarakji
- Tarantini
- Tardif
- Tatti
- Taylor
- Taylor
- Taylor
- Taylor
- Taylor
- Taylor
- Taylor
- Tepper
- Thiele
- Thiele
- Thomas
- Thomas C. Gerber
- Thompson
- Thompson
- Timmis
- Todd
- Tonino
- Toole
- Topol
- Treese
- Trikalinos
- Trikalinos
- Tsuya
- Tsuyuki
- Tummala
- Tuomilehto
- Turnbull
- Turnbull
- Turnbull
- Underwood
- Underwood
- Underwood
- Urano
- Ussher
- Vaccarino
- Vaccarino
- Valdiviezo
- Van Camp
- van der Bijl
- van der Sloot
- van Rij
- van Velzen
- van Werkhoven
- VandenBurg
- Varani
- Vardeny
- Varnauskas
- Vassiliades
- Velazquez
- Villarruz
- Villines
- Vineberg
- Vitarelli
- Vivekananthan
- von Arnim
- von Beckerath
- Vongvanich
- Wagdy
- Wahrborg
- Wallace
- Wallentin
- Waters
- Waysbort
- Weiner
- Weiner
- Weintraub
- Weintraub
- Weintraub
- Wenaweser
- West
- Whelton
- Whelton
- Whelton
- White
- Whooley
- Whooley
- Wiest
- Wight
- Wijeysundera
- Wijeysundera
- Wijns
- Willett
- Wilson
- Wilt
- Winniford
- Winter
- Wiviott
- Wong
- Woodcock
- Worm
- Wright
- Wright
- Wu
- Xie
- Xin
- Yang
- Yang
- Yao
- Yao
- Yao
- Yoshinaga
- Yoshinaga
- Yu-Poth
- Yusuf
- Yusuf
- Yusuf
- Yusuf
- Yusuf
- Yusuf
- Zeiher
- Zethelius
- Zhao
- Ziegelstein
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study