462 research outputs found
Clusters of alcohol abstainers and drinkers incorporating motives against drinking: a random survey of 18 to 34 year olds in four cities in four different continents
- Author
- Abbey A Smith MJ, Scott RO
- Anderson KG Briggs KEL, White HR
- Anderson KG Grunwald I, Bekman N, et al.
- Astudillo M Connor J, Roiblatt RE, et al.
- Bernards S Graham K, Kuendig H, et al.
- Blume AW Guttu BL
- Cheng HG Phillips MR, Zhang Y, et al.
- Christie-Mizell CA Peralta RL
- Clausen T Rossow I, Naidoo N, et al.
- Cochrane J Chen H, Conigrave KM, et al.
- Costanzo PR Malone PS, Belsky D, et al.
- Davies EL Conroy D, Winstock AR, et al.
- Daw J Margolis R, Wright L
- Dietler M
- Dumbili EW
- Epler AJ Sher KJ, Piasecki TM
- Erol A Karpyak VM
- Esan O Makanjuola V, Oladeji B, et al.
- Ferreira MP Willoughby D
- Galen LW Rogers WM
- Hall WD Patton G, Stockings, et al.
- Ibanga AKJ Adetula VAO, Dagona ZK
- Jiafang Z Jiachun W, Yunxia L, et al.
- Joosten J Knibbe RA, Derickx M
- Keenan K Saburova L, Bobrova N, et al.
- Khaltourina D Korotayev A
- Kuntsche E Gabhainn SN, Roberts C, et al.
- Kuntsche E Knibbe R, Gmel G, et al.
- Loose T Acier D
- Loxton NJ Bunker RJ, Dingle GA, et al.
- Mezquita L Stewart SH, Ibanez MI, et al.
- Patrick ME Wray-Lake L, Finlay AK, et al.
- Slater MD Basil MD, Maibach EW
- Stritzke WGK Butt JCM
- Taylor AW Bewick BM, Makanjuola AB,et al.
- Van Gundy K
- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2018
- Field of study
Objective: The aim of this analysis was to identify alcohol consumption clusters for adolescents and early adults according to attitudes to drinking, motivations against drinking and perceptions associated with alcohol. Method: Interviews were undertaken with people aged 18â34 years old living in four cities in different regions of the world. Multistage random sampling was consistent across the four cities (Ilorin (Nigeria), Wuhan (China), Montevideo (Uruguay) and Moscow (Russia)). The questionnaire was forward and back translated into relevant languages and face-to-face interviewing undertaken. The data were weighted to the population of each city. In total 6235 structured interviews were undertaken (1391 in Ilorin, 1600 in Montevideo, 1604 in Moscow and 1640 in Wuhan). Questions regarding motivation against alcohol consumption (14 items), assessing perceptions (3 items) and attitudes to drinking in certain situations (8 items) were asked of all respondents including abstainers. Factor analysis was initially undertaken to identify highly related correlated variables. Results: Cluster analysis provided a variety of clusters (Ilorin (3 clusters), Montevideo (5), Moscow (4) and Wuhan (4)). At least one cluster in each city was dominated by abstainers and another by heavy episodic drinkers. Variations by city and alcohol consumption patterns existed in regards to variables included. Conclusion: This analysis detailed the city specific motivations against drinking alcohol, and the attitudes towards alcohol consumption. Differences highlight the influence of country/city specific culture, customs, laws, societal norms and traditions
Three-Dimensional Neurophenotyping of Adult Zebrafish Behavior
- Author
- A Stewart
- Adam Stewart
- AF Sarrazin
- AL Rubinstein
- Alessandro Bartolomucci
- Allan V. Kalueff
- AS Kane
- B Lockwood
- BH Bleakley
- BW Patullo
- C Hicks
- C Jadot
- C Maximino
- C Maximino
- C Maximino
- C Maximino
- C Renier
- C Salas
- C Saverino
- CA Dlugos
- CY Fan
- D Alsop
- D Alsop
- D Echevarria
- D Eddins
- D Wright
- DH Thorsen
- DL Champagne
- E Choleris
- E Fontaine
- ED Levin
- ED Levin
- ED Levin
- Eli Utterback
- ET Larson
- Evan Kyzar
- G Ros-Sanchez
- GC Paull
- I Huse
- IM McGonnell
- IS Kwak
- J Cachat
- J Cachat
- J Cachat
- J Delcourt
- J Delcourt
- J Rihel
- J Sackerman
- JA Morris
- JD Best
- JM Cachat
- JM Cachat
- Jonathan Cachat
- K Fero
- K Nimkerdphol
- K Suzuki
- K Wong
- K Wong
- Keith Wong
- KJ Webb
- KO Darrow
- L Grossman
- L Prut
- L Zhu
- LA Fuiman
- LM Gomez-Laplaza
- M McHenry
- M Westerfield
- MA MacIver
- MA MacIver
- MB McElligott
- N Graham
- N Miller
- N Peitsaro
- N Speedie
- Nadine Wu
- P Laube
- P Panula
- P Panula
- Peter Hart
- R Blaser
- R Gerlai
- R Gerlai
- R Gerlai
- R Gerlai
- R Gerlai
- R Gerlai
- R Redolat
- RE Blaser
- RE Engeszer
- RJ Egan
- S Dodge
- S Kato
- S Lee
- SA Budick
- Siddharth Gaikwad
- T Burne
- TS Chon
- W Norton
- W Shannon
- Y Xi
- YC Chen
- YS Park
- Z Bencan
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
The use of adult zebrafish (Danio rerio) in neurobehavioral research is rapidly expanding. The present large-scale study applied the newest video-tracking and data-mining technologies to further examine zebrafish anxiety-like phenotypes. Here, we generated temporal and spatial three-dimensional (3D) reconstructions of zebrafish locomotion, globally assessed behavioral profiles evoked by several anxiogenic and anxiolytic manipulations, mapped individual endpoints to 3D reconstructions, and performed cluster analysis to reconfirm behavioral correlates of high- and low-anxiety states. The application of 3D swim path reconstructions consolidates behavioral data (while increasing data density) and provides a novel way to examine and represent zebrafish behavior. It also enables rapid optimization of video tracking settings to improve quantification of automated parameters, and suggests that spatiotemporal organization of zebrafish swimming activity can be affected by various experimental manipulations in a manner predicted by their anxiolytic or anxiogenic nature. Our approach markedly enhances the power of zebrafish behavioral analyses, providing innovative framework for high-throughput 3D phenotyping of adult zebrafish behavior
Efficient Network Reconstruction from Dynamical Cascades Identifies Small-World Topology of Neuronal Avalanches
- Author
- A Barrat
- A Brovelli
- A Levina
- A Mazzoni
- A Tang
- A Trusina
- A Vazquez
- AA Prinz
- AL BarabĂĄsi
- AT Ihler
- B Gourevitch
- B Gourévitch
- C Mehring
- C Zhou
- CJ Honey
- CJ Stam
- CV Stewart
- CV Stewart
- D Brockmann
- D Eytan
- D Heckerman
- D Plenz
- Dietmar Plenz
- DJ Felleman
- DJ Watts
- DS Bassett
- E Schneidman
- ED Gireesh
- ET Jaynes
- G Palm
- GA Cecchi
- GF Cooper
- GL Gerstein
- GL Pellegrini
- H Jeffries
- H Jeong
- HE Stanley
- I Baruchi
- J Beggs
- J le Feber
- J Ozik
- J Teramae
- JA Hartigan
- JC Prechtl
- JM Beggs
- JM Bernardo
- JW Scannell
- KV Srinivas
- L de Arcangelis
- L Hufnagel
- LAN Amaral
- LC Jia
- LF Abbott
- LMA Bettencourt
- M Abeles
- M Kaiser
- M Kaiser
- M KamiĆski
- M Okatan
- MEJ Newman
- MEJ Newman
- MI Ham
- MP Young
- N Friedman
- O Sporns
- O Sporns
- Olaf Sporns
- P Bak
- PG Lind
- R Segev
- RE Neapolitan
- S Achard
- S Guo
- S Maslov
- S Pajevic
- S Pajevic
- S Yu
- SH Strogatz
- Sinisa Pajevic
- T Bayes
- T Schreiber
- TE Harris
- TR Lezon
- V Braitenberg
- V Pasquale
- VM EguĂluz
- WA Schmitt Jr
- Y Dan
- Y Ikegaya
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2009
- Field of study
Cascading activity is commonly found in complex systems with directed
interactions such as metabolic networks, neuronal networks, or disease spreading
in social networks. Substantial insight into a system's organization
can be obtained by reconstructing the underlying functional network architecture
from the observed activity cascades. Here we focus on Bayesian approaches and
reduce their computational demands by introducing the Iterative Bayesian (IB)
and Posterior Weighted Averaging (PWA) methods. We introduce a special case of
PWA, cast in nonparametric form, which we call the normalized count (NC)
algorithm. NC efficiently reconstructs random and small-world functional network
topologies and architectures from subcritical, critical, and supercritical
cascading dynamics and yields significant improvements over commonly used
correlation methods. With experimental data, NC identified a functional and
structural small-world topology and its corresponding traffic in cortical
networks with neuronal avalanche dynamics
Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at â s = 8 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abbott DC
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abud AA
- Abulaiti Y
- Acharya BS
- Achkar B
- Adachi S
- Adam L
- Adamczyk L
- Adamek L
- Adelman J
- Adersberger M
- Adiguzel A
- Adorni S
- Adye T
- Affolder AA
- Afik Y
- Agapopoulou C
- Agaras MN
- Aggarwal A
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahmadov F
- Ahmed WS
- Ai X
- Aielli G
- Akatsuka S
- Akesson TPA
- Akilli E
- Akimov A
- Al Khoury K
- Alberghi GL
- Albert J
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexopoulos T
- Alfonsi A
- Alfonsi F
- Alhroob M
- Ali B
- Aliev M
- Alimonti G
- Allaire C
- Allbrooke BMM
- Allen BW
- Allport PP
- Aloisio A
- Alonso F
- Alpigiani C
- Alshehri AA
- Alvarez Estevez M
- Alviggi MG
- Amaral Coutinho Y
- Ambler A
- Ambroz L
- Amelung C
- Amidei D
- Amor Dos Santos SP
- Amoroso S
- Amrouche CS
- An F
- Anastopoulos C
- Andari N
- Andeen T
- Anders CF
- Anders JK
- Andreazza A
- Andrei V
- Anelli CR
- Angelidakis S
- Angerami A
- Anisenkov A
- Annovi A
- Antel C
- Anthony MT
- Antipov E
- Antonelli M
- Antrim DJA
- Anulli F
- Aoki M
- Aparisi Pozo JA
- Araque JP
- Araujo Ferraz V
- Araujo Pereira R
- Araya ST
- Arcangeletti C
- Arce ATH
- Arduh FA
- Arguin J-F
- Argyropoulos S
- Arling J-H
- Armbruster AJ
- Armstrong A
- Arnaez O
- Arnold H
- Artoni G
- Artz S
- Asai S
- Asawatavonvanich T
- Asbah N
- Asimakopoulou EM
- Asquith L
- Assahsah J
- Assamagan K
- Astalos R
- Astigarraga MEP
- Atkin RJ
- Atkinson M
- Atlay NB
- Atmani H
- Augsten K
- Avolio G
- Ayoub MK
- Azuelos G
- Bachacou H
- Bachas K
- Backes M
- Backman F
- Bagnaia P
- Bahmani M
- Bahrasemani H
- Bailey AJ
- Bailey VR
- Baines JT
- Bakalis C
- Baker OK
- Bakker PJ
- Balaji S
- Baldin EM
- Balek P
- Balli F
- Balunas WK
- Balz J
- Banas E
- Bandyopadhyay A
- Banerjee S
- Bannoura AAE
- Barak L
- Barbe WM
- Barberio EL
- Barberis D
- Barbero M
- Barbour G
- Barillari T
- Barisits M-S
- Barkeloo J
- Barklow T
- Barnea R
- Barnett BM
- Barnett RM
- Barnovska-Blenessy Z
- Baroncelli A
- Barone G
- Barr AJ
- Barreiro F
- Barsov S
- Bartoldus R
- Bartolini G
- Barton AE
- Bartos P
- Basalaev A
- Basan A
- Bassalat A
- Basso MJ
- Bates RL
- Batlamous S
- Batley JR
- Batool B
- Battaglia M
- Bauce M
- Bauer F
- Bauer KT
- Bawa HS
- Beacham JB
- Beau T
- Beauchemin PH
- Becherer F
- Bechtle P
- Beck HC
- Beck HP
- Becker K
- Becot C
- Beddall A
- Beddall AJ
- Bednyakov VA
- Bedognetti M
- Beermann TA
- Begalli M
- Begel M
- Behera A
- Behr JK
- Beisiegel F
- Bell AS
- Bella G
- Bella LA
- Bellagamba L
- Bellerive A
- Bellos P
- Beloborodov K
- Belotskiy K
- Belyaev NL
- Benchekroun D
- Benekos N
- Benhammou Y
- Benjamin DP
- Benoit M
- Bensinger JR
- Bentvelsen S
- Beresford L
- Beretta M
- Berge D
- Berger N
- Bergmann B
- Bergsten LJ
- Beringer J
- Berlendis S
- Berlingen JM
- Bernardi G
- Bernius C
- Bernlochner FU
- Berry T
- Berta P
- Bertella C
- Bertram IA
- Besson N
- Bethani A
- Bethke S
- Betti A
- Bevan AJ
- Beyer J
- Bhattacharya DS
- Bhattarai P
- Bi R
- Bianchi RM
- Biebel O
- Biedermann D
- Bielski R
- Bierwagen K
- Biesuz N
- Biglietti M
- Billoud TR
- Bindi M
- Bingul A
- Bini C
- Biondi S
- Birman M
- Bisanz T
- Biswal JP
- Biswas D
- Bitadze A
- Bittrich C
- Bjorke K
- Blazek T
- Bloch I
- Blocker C
- Blue A
- Blumenschein U
- Bobbink GJ
- Bobrovnikov VS
- Bocchetta SS
- Bocci A
- Boeriu OEV
- Boerner D
- Bogavac D
- Bogdanchikov AG
- Bohm C
- Boisvert V
- Bokan P
- Bold T
- Bolz AE
- Bomben M
- Bona M
- Bonilla JS
- Boonekamp M
- Booth CD
- Borecka-Bielska HM
- Borgna LS
- Borisov A
- Borissov G
- Bortfeldt J
- Bortoletto D
- Boscherini D
- Bosman M
- Bostanabad MG
- Bouaouda K
- Boudreau J
- Bouhova-Thacker E
- Boumediene D
- Bourdarios CA
- Boutle SK
- Boveia A
- Boyd J
- Boye D
- Boyko IR
- Bozson AJ
- Bracinik J
- Brahimi N
- Brandt G
- Brandt O
- Braren F
- Brau B
- Brau JE
- Brendlinger K
- Brenner L
- Brenner R
- Bressler S
- Bret MC
- Brickwedde B
- Briglin DL
- Britton D
- Britzger D
- Brock I
- Brock R
- Brooijmans G
- Brooks WK
- Brost E
- Broughton JH
- Bruncko D
- Bruni A
- Bruni G
- Bruni LS
- Bruno S
- Bruschi M
- Bruscino N
- Bryant P
- Bryngemark L
- Buanes T
- Buat Q
- Buchholz P
- Buckley AG
- Budagov IA
- Buehrer F
- Buescher V
- Bugge MK
- Bulekov O
- Burch TJ
- Burdin S
- Burgard CD
- Burger AM
- Burghgrave B
- Burr JTP
- Burton CD
- Burzynski JC
- Buschmann E
- Bussey PJ
- Butler JM
- Buttar CM
- Butterworth JM
- Butti P
- Buttinger W
- Buzatu A
- Buzykaev AR
- Bylund OB
- Cabras G
- Cabrera Urban S
- Caforio D
- Cai H
- Cairo VMM
- Cakir IT
- Cakir O
- Calace N
- Calafiura P
- Calandri A
- Calderini G
- Calfayan P
- Callea G
- Caloba LP
- Caltabiano A
- Calvente Lopez S
- Calvet D
- Calvet S
- Calvet TP
- Calvetti M
- Camarda S
- Camarero Munoz D
- Camarri P
- Camelia EA
- Cameron D
- Camincher C
- Campana S
- Campanelli M
- Camplani A
- Campoverde A
- Canale V
- Canesse A
- Cantero J
- Cao T
- Cao Y
- Capua M
- Cardarelli R
- Cardillo F
- Carducci G
- Carli I
- Carli T
- Carlino G
- Carlson BT
- Carminati L
- Carney RMD
- Caron S
- Carquin E
- Carra S
- Carter JWS
- Casado MP
- Casha AF
- Casper DW
- Castelijn R
- Castillo Garcia L
- Castillo Gimenez V
- Castillo FL
- Castillo LRF
- Castro NF
- Catinaccio A
- Catmore JR
- Cattai A
- Cavaliere V
- Cavallaro E
- Cavalli-Sforza M
- Cavasinni V
- Celebi E
- Cerda Alberich L
- Cerny K
- Cerqueira AS
- Cerri A
- Cerrito L
- Cerutti F
- Cervelli A
- Cetin SA
- Chadi Z
- Chakraborty D
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- Chan WS
- Chan WY
- Chapman JD
- Chargeishvili B
- Charlton DG
- Charman TP
- Chau CC
- Che S
- Chekanov S
- Chekulaev S
- Chelkov GA
- Chen B
- Chen C
- Chen CH
- Chen H
- Chen J
- Chen S
- Chen SJ
- Chen X
- Chen Y-H
- Cheng HC
- Cheng HJ
- Cheplakov A
- Cheremushkina E
- Cheu E
- Cheung K
- Chevalerias TJA
- Chevalier L
- Chiarella V
- Chiarelli G
- Chiodini G
- Chisholm AS
- Chitan A
- Chiu I
- Chiu YH
- Chizhov M
- Choi K
- Chomont AR
- Chouridou S
- Chow YS
- Chu MC
- Chu X
- Chudoba J
- Chwastowski JJ
- Chytka L
- Cieri D
- Ciesla KM
- Cinca D
- Cindro V
- Cioara IA
- Ciocio A
- Cirotto F
- Citron ZH
- Citterio M
- Ciubotaru DA
- Ciungu BM
- Clark A
- Clark MR
- Clark PJ
- Clement C
- Coadou Y
- Cobal M
- Coccaro A
- Cochran J
- Cohen H
- Coimbra AEC
- Cole B
- Colijn AP
- Collot J
- Conde Muino P
- Connell SH
- Connelly IA
- Constantinescu S
- Conventi F
- Cooper-Sarkar AM
- Corga KDV
- Cormier F
- Cormier KJR
- Cornell SD
- Corpe LD
- Corradi M
- Correia AMH
- Corrigan EE
- Corriveau F
- Costa MJ
- Costanza F
- Costanzo D
- Cowan G
- Cowley JW
- Crane J
- Cranmer K
- Crawley SJ
- Creager RA
- Crepe-Renaudin S
- Crescioli F
- Cristinziani M
- Croft V
- Crosetti G
- Cueto A
- Cukierman AR
- Cunningham WR
- Czekierda S
- Czodrowski P
- D'amen G
- D'Amico V
- D'Auria S
- D'Eramo L
- da Costa JBG
- Da Fonseca Pinto J
- Da Via C
- Dabrowski W
- Dachs F
- Dado T
- Dahbi S
- Dai T
- Dallapiccola C
- Dam M
- Damazio DO
- Damp J
- Dandoy JR
- Daneri MF
- Dann NS
- Danninger M
- Dao V
- Darbo G
- Dartsi O
- Dattagupta A
- Daubney T
- David C
- Davidek T
- Davis DR
- Dawson I
- De Asmundis R
- De Beurs M
- De Castro S
- De Cecco S
- De Groot N
- de Jong P
- De la Torre H
- de Lima DEF
- De Lima RT
- De Maria A
- De Pedis D
- De Regie JBDV
- de Renstrom PAB
- De Sa RCL
- De Salvo A
- De Sanctis U
- De Santis M
- De Santo A
- De Sousa MJDCS
- De K
- Debenedetti C
- Dedovich D
- Deiana AM
- Del Peso J
- Delgove D
- Deliot F
- Delitzsch CM
- Dell'Acqua A
- Dell'Asta L
- Della Pietra M
- Della Volpe D
- Delmastro M
- Delporte C
- Delsart PA
- DeMarco DA
- Demers S
- Demichev M
- Demontigny G
- Denisov SP
- Derendarz D
- Derkaoui JE
- Derue F
- Dervan P
- Desch K
- Deterre C
- Dette K
- Deutsch C
- Devesa MR
- Deviveiros PO
- Di Bello FA
- Di Ciaccio A
- Di Ciaccio L
- Di Clemente WK
- Di Donato C
- Di Girolamo A
- Di Gregorio G
- Di Micco B
- Di Nardo R
- Di Petrillo KF
- Di Sipio R
- Diaconu C
- Dias FA
- Diaz LP
- Diaz MA
- Diaz YD
- Dickinson J
- Diehl EB
- Dietrich J
- Dimitrievska A
- Ding W
- Dingfelder J
- Dittus F
- Djama F
- Djobava T
- Djuvsland J
- Do Vale TD
- Dobre M
- Dodsworth D
- Doglioni C
- Dolejsi J
- Dolezal Z
- Dominguez LP
- Don MMR
- Donadelli M
- Dong B
- Donini J
- Donszelmann TC
- Dopke J
- Doria A
- Dova MT
- Doyle AT
- Drechsler E
- Dreyer E
- Dreyer T
- Drobac AS
- Du D
- Duan Y
- Dubinin F
- Dubovsky M
- Dubreuil A
- Duchovni E
- Duckeck G
- Ducourthial A
- Ducu OA
- Duda D
- Dudarev A
- Dudder AC
- Duelsen C
- Dueren M
- Duffeld EM
- DuflOt L
- Duhrssen M
- Dumancic M
- Dumitriu AE
- Duncan AK
- Dunford M
- Duperrin A
- Durglishvili A
- Duschinger D
- Dutta B
- Duvnjak D
- Dyckes G
- Dyndal M
- Dysch S
- Dziedzic BS
- Ecker KM
- Eggleston MG
- Eifert T
- Eigen G
- Einsweiler K
- Ekelof T
- El Jarrari H
- El Kossei R
- El Moursli RC
- Ellajosyula V
- Ellert M
- Ellinghaus F
- Elliot AA
- Ellis N
- Elmsheuser J
- Elsing M
- Emeliyanov D
- Emerman A
- Enari Y
- Epland MB
- Erdmann J
- Ereditato A
- Erland PA
- Errenst M
- Escalier M
- Escobar C
- Estrada Pastor O
- Etzion E
- Evans H
- Ezhilov A
- Fabbri F
- Fabbri L
- Fabiani V
- Facini G
- Fakhrutdinov RM
- Falciano S
- Falke PJ
- Falke S
- Faltova J
- Fang Y
- Fanourakis G
- Fanti M
- Faraj M
- Farbin A
- Farilla A
- Farina EM
- Farooque T
- Farrington SM
- Farthouat P
- Fassi F
- Fassnacht P
- Fassouliotis D
- Fawcett WJ
- Fayard L
- Fedin OL
- Fedorko W
- Fehr A
- Feickert M
- Feligioni L
- Fell A
- Feng C
- Feng M
- Fenton MJ
- Fenyuk AB
- Ferguson SW
- Ferrando J
- Ferrante A
- Ferrari A
- Ferrari P
- Ferrari R
- Ferrer A
- Ferrer JAV
- Ferrere D
- Ferretti C
- Fiedler F
- Filipcic A
- Filthaut F
- Finelli KD
- Fiolhais MCN
- Fiorini L
- Fischer F
- Fisher WC
- Fleck I
- Fleischmann P
- Flick T
- Flierl BM
- Flores L
- Follega FM
- Fomin N
- Foo JH
- Forcolin GT
- Formica A
- Forster FA
- Forti AC
- Foster AG
- Foti MG
- Fournier D
- Fox H
- Francavilla P
- Francescato S
- Franchini M
- Franchino S
- Francis D
- Franconi L
- Franklin M
- Fray AN
- Freeman PM
- Freund B
- Freund WS
- Freundlich EM
- Frizzell DC
- Froidevaux D
- Frost JA
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- Zhemchugov A
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- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fbâ1 of â s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
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- Ahlen SP
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- Aktas A
- Alam MA
- Alam MS
- Albert J
- Albrand S
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- Aleksandrov IN
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- Alexa C
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of âs = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pTâ„20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60â€pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2â€{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration
Search for the neutral Higgs bosons of the minimal supersymmetric standard model in pp collisions at root s=7 TeV with the ATLAS detector
- Author
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- Wijeratne PA
- Wildauer A
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- Wilkens HG
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- Williams HH
- Williams S
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- Wilson JA
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- Winkelmann S
- Winklmeier F
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- Xie S
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- Yabsley B
- Yacoob S
- Yagci KD
- Yamada N
- Yamaguchi H
- Yamamoto A
- Yamamoto K
- Yamamoto S
- Yamamura T
- Yamanaka T
- Yamauchi K
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang H
- Yang H
- Yang UK
- Yang Y
- Yang Z
- Yanush S
- Yao L
- Yasu Y
- Yatsenko E
- Ye J
- Ye S
- Yen AL
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Yoshihara K
- Young C
- Young CJ
- Youssef S
- Yu D
- Yu DR
- Yu J
- Yu J
- Yuan L
- Yurkewicz A
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zanello L
- Zanzi D
- Zaytsev A
- Zeitnitz C
- Zeman M
- Zemla A
- Zenin O
- Zenis T
- Zerwas D
- Zhang D
- Zhang H
- Zhang J
- Zhang X
- Zhang Z
- Zhao L
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
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- Zhou Y
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- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- Publication date
- 01/02/2013
- Field of study
A search for neutral Higgs bosons of the Minimal Supersymmetric Standard Model (MSSM) is reported. The analysis is based on a sample of proton-proton collisions at a centre-of-mass energy of 7TeV recorded with the ATLAS detector at the Large Hadron Collider. The data were recorded in 2011 and correspond to an integrated luminosity of 4.7 fb-1 to 4.8 fb-1. Higgs boson decays into oppositely-charged muon or Ï lepton pairs are considered for final states requiring either the presence or absence of b-jets. No statistically significant excess over the expected background is observed and exclusion limits at the 95% confidence level are derived. The exclusion limits are for the production cross-section of a generic neutral Higgs boson, Ï, as a function of the Higgs boson mass and for h/A/H production in the MSSM as a function of the parameters mA and tan ÎČ in the mhmax scenario for mA in the range of 90GeV to 500 GeV. Copyright CERN
Using death to one's advantage: HIV modulation of apoptosis
- Author
- A Algeciras
- A Anel
- A Badley
- A Cafaro
- A Greeway
- A Kelekar
- A Kinter
- AD Osterhaus
- AG Laurent-Crawford
- AH Wyllie
- AJ Darmon
- AJ Minn
- AL Van
- AM Chinnaiyan
- AS Baur
- B Conradt
- B Ensoli
- BR Cullen
- BR Gundlach
- C Aiken
- C Baumler
- C Cicala
- C Cicala
- C Terai
- CA Ray
- CD Bortner
- D Ho
- D Reinhold
- D Xue
- D Zagury
- D Zagury
- DE Croal
- DF Nixon
- DiMarzio
- DJ Li
- DK Miller
- DN Levy
- DR Hodge
- E Rapaport
- EA Cohen
- EB Stephens
- EN Kraiselburd
- ES Alnemri
- ET Sawai
- ET Sawai
- F Cocchi
- F Margottin
- F Re
- G Alkhatib
- G Alkhatib
- G Hacker
- G Herbein
- G Herbein
- G Pan
- G Zauli
- GD Edwart
- GL Stivahtis
- H Choe
- H Deng
- H Okada
- HL Robinson
- I Agostini
- I Szabo
- J Bertin
- J Dhein
- J Estaquirer
- J He
- J Hesselgesser
- J Hua
- J Lama
- J Savill
- JBM Jowett
- JC Ameisen
- JC Ameisen
- JC Reed
- JE Rosok
- JG Teodoro
- JM Adams
- JV Garcia
- JW Balliet
- K Ogawa
- K Shasty
- K Strebel
- KA Jones
- KL Collins
- KM Murphy
- KP Wilson
- L Alexander
- L Meyaard
- L Selig
- L Wang
- L Zheng
- LM Mansky
- LT Quan
- M Alderson
- M Bouhamdan
- M Ui
- M Westendorp
- MA Vodicka
- MC Gauduin
- MD Hazenberg
- ME Rogel
- MG Hengartner
- MS Wyand
- MX Wu
- N Chirmule
- N Hattori
- NK Heinzinger
- P Gallay
- PA Sandstrom
- PD Katsikis
- PD Katsikis
- PJ Maddon
- R Antonasson
- R Gehri
- RA Black
- RI Connor
- RJ Clem
- RP Viscidi
- RT Allen
- S Bour
- S Hodge
- S Mahalingam
- S Schendel
- S Sieg
- S Wang
- S-T Ju
- SA Stewart
- SF Purvis
- SR Bartz
- SR D'Mello
- SS Cohen
- T Brunner
- TH Finkel
- TM Ross
- TM Ross
- U Schubert
- V Cryns
- V Cryns
- V Kolensnitchenko
- W Paxton
- WMS Guntheil
- X Lu
- X-J Yao
- X-N Xu
- Y Collette
- Y Hu
- YBC Feng
- YL Lu
- Z Wang
- Publication venue
- 'East Carolina University'
- Publication date
- 01/03/2001
- Field of study
Infection by human immunodeficiency virus (HIV) is associated with an early immune dysfunction and progressive destruction of CD4+ T lymphocytes. This progressive disappearance of T cells leads to a lack of immune control of HIV replication and to the development of immune deficiency resulting in the increased occurrence of opportunistic infections associated with acquired immune deficiency syndrome (AIDS). The HIV-induced, premature destruction of lymphocytes is associated with the continuous production of HIV viral proteins that modulate apoptotic pathways. The viral proteins, such as Tat, Env, and Nef, are associated with chronic immune activation and the continuous induction of apoptotic factors. Viral protein expression predisposes lymphocytes, particularly CD4+ T cells, CD8+ T cells, and antigen-presenting cells, to evolve into effectors of apoptosis and as a result, to lead to the destruction of healthy, non-infected T cells. Tat and Nef, along with Vpu, can also protect HIV-infected cells from apoptosis by increasing anti-apoptotic proteins and down- regulating cell surface receptors recognized by immune system cells. This review will discuss the validity of the apoptosis hypothesis in HIV disease and the potential mechanism(s) that HIV proteins perform in the progressive T cell depletion observed in AIDS pathogenesis. Originally published Leukemia, Vol. 15, No. 3, Mar 200
Climate Change, Coral Reef Ecosystems, and Management Options for Marine Protected Areas
- Author
- A Bakun
- A Baldwin
- A Friedlander
- A Hastings
- A Shepherd
- AA Rosenberg
- AC Baker
- AE Douglas
- AL Perry
- AL Shanks
- Alan M. Friedlander
- B Cicin-Sain
- B Dickson
- B Michaelidis
- BI McNeil
- Billy D. Causey
- BJ Peterson
- BP Kinlan
- Brian D. Keller
- BS Halpern
- C Cabanes
- C Langdon
- C Mora
- C Wilkinson
- CB Munn
- CB Paris
- CD Harvell
- CD Harvell
- CDG Harley
- CG Soto
- CH Greene
- Christa M. Woodley
- CL Sabine
- CM Roberts
- CM Roberts
- CM Roberts
- CM Roberts
- CM Roberts
- CM Roberts
- CM Roberts
- CR Wilkinson
- CR Wilkinson
- CR Wilkinson
- CR Wilkinson
- D Harvell
- D Lirman
- D Pauly
- D Pauly
- D Scavia
- Daniel F. Gleason
- DB Snyder
- DE Burkepile
- DL Albritton
- DL Breitburg
- DM Baltz
- DR Bellwood
- DR Bellwood
- DR Bellwood
- DR Robertson
- DW Freshwater
- E McLeod
- E Rignot
- ED McCoy
- EE Sotka
- EF Pane
- Elizabeth McLeod
- EN Edinger
- ET Game
- F Micheli
- GA Burton Jr
- GE Davis
- GM Ruiz
- GP Jones
- GP Jones
- GR Walther
- GW Allison
- GW Allison
- H Galbraith
- HK Lotze
- HV Boyett
- HV McGregor
- I Mosquera
- I Nagelkerken
- J Engel
- JA Bohnsack
- JA Estes
- JA Kleypas
- JA Kleypas
- JA McGowan
- JA Sobel
- JBC Jackson
- JC Ogden
- JC Orr
- JE Johnson
- JF Bruno
- JG Hiddink
- JK Reaser
- JL Chen
- JM Coe
- JM Pandolfi
- JM Pandolfi
- JM Roberts
- JM Roessig
- JM West
- Johanna E. Johnson
- JP Barry
- JP McCarty
- JT Carlton
- JT Carlton
- JT Tilmant
- JW McManus
- JW Porter
- JW Porter
- K Caldeira
- K Engie
- K Kim
- KD Hyrenbach
- KE Fabricius
- KH Mann
- KK Yates
- KP Boessenkool
- KRT Whelan
- KT Frank
- L Burke
- L Burke
- L Cho
- L Fernandes
- L Kaufman
- LB Crowder
- LB Crowder
- LD Mydlarz
- LH Gunderson
- LR Gerber
- LS Mills
- M Beger
- M Khamer
- M Nyström
- M Ruckelshaus
- MA Hixon
- MA Snyder
- MD Behrens
- ME Kimball
- MH Carr
- MH Ledlie
- MJ Kaiser
- MJ McPhaden
- MP Lesser
- MP Marchetti
- MV Moore
- NAJ Graham
- National Marine Fisheries Service (NMFS)
- National Research Council (NRC)
- NJ Mantua
- NK Dulvy
- NL Bindoff
- NN Rabalais
- NRC
- O Hoegh-Guldberg
- O Hoegh-Guldberg
- O Hoegh-Guldberg
- P Hallock
- P Marshall
- P Marshall
- PA Fields
- PAR Hockey
- PB Moyle
- PE Whitfield
- Pew Oceans Commission (POC)
- PF Sale
- PJ Mumby
- PJ Mumby
- PK Dayton
- R Berkelmans
- R Condrey
- R Curry
- R Curry
- R Law
- RA Feely
- RB Aronson
- RE Bell
- Rikki Grober-Dunsmore
- RJ Nicholls
- RJ Orth
- RJT Klein
- RK Cowen
- RK Cowen
- Robert S. Steneck
- RR Stewart
- RR Warner
- RS Steneck
- RS Steneck
- RS Steneck
- RS Steneck
- RV Salm
- RW Grigg
- S Airamé
- S Philip
- S Wells
- SA Levin
- SA Murawski
- Satie Airamé
- SD Donner
- SD Donner
- SE Edge
- SE Edge
- SE Swearer
- SF Thrush
- SJ McNaughton
- SR Carpenter
- SR Palumbi
- SR Palumbi
- SR Palumbi
- SR Palumbi
- SR Palumbi
- SR Palumbi
- SR Thorrold
- Steven L. Miller
- SV Smith
- T Done
- TA Gardner
- TA Gardner
- The Royal Society (TRS)
- TJ Done
- TP Hughes
- TP Hughes
- TR McClanahan
- US Department of Commerce (USDOC)
- WF Precht
- WK Fitt
- WP Sousa
- Y Sadovy
- Y Shirayama
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2009
- Field of study
Marine protected areas (MPAs) provide place-based management of marine ecosystems through various degrees and types of protective actions. Habitats such as coral reefs are especially susceptible to degradation resulting from climate change, as evidenced by mass bleaching events over the past two decades. Marine ecosystems are being altered by direct effects of climate change including ocean warming, ocean acidification, rising sea level, changing circulation patterns, increasing severity of storms, and changing freshwater influxes. As impacts of climate change strengthen they may exacerbate effects of existing stressors and require new or modified management approaches; MPA networks are generally accepted as an improvement over individual MPAs to address multiple threats to the marine environment. While MPA networks are considered a potentially effective management approach for conserving marine biodiversity, they should be established in conjunction with other management strategies, such as fisheries regulations and reductions of nutrients and other forms of land-based pollution. Information about interactions between climate change and more âtraditionalâ stressors is limited. MPA managers are faced with high levels of uncertainty about likely outcomes of management actions because climate change impacts have strong interactions with existing stressors, such as land-based sources of pollution, overfishing and destructive fishing practices, invasive species, and diseases. Management options include ameliorating existing stressors, protecting potentially resilient areas, developing networks of MPAs, and integrating climate change into MPA planning, management, and evaluation
Pan-cancer analysis of whole genomes
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- The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium View Correspondence (jump link)
- Thiessen
- Thomas
- Thomas
- Thompson
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- Thorne
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- Thorogood
- Tijanic
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- Zhang H. b
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- Zheng
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- zm Jayaseelan
- Zou
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- zt Kim
- zw Lewis
- Ă. A. th
- Ă. sk
- Publication venue
- Publication date
- 11/12/2019
- Field of study
Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale(1-3). Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4-5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter(4); identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation(5,6); analyses timings and patterns of tumour evolution(7); describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity(8,9); and evaluates a range of more-specialized features of cancer genomes(8,10-18).Peer reviewe
Measurement of the cross section for inclusive isolated-photon production in pp collisions at âs=13TeV using the ATLAS detector
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- Aaboud M
- Aad G
- Abbott B
- Abdinov O
- Abeloos B
- Abidi SH
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- Acharya BS
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- Akesson TPA
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- Yigitbasi E
- Yildirim E
- Yildiz HD
- Yorita K
- Yoshihara K
- Young C
- Young CJS
- Yu J
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- Yusuff I
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- Zacharis G
- Zaidan R
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- Zakharchuk N
- Zalieckas J
- Zaman A
- Zambito S
- Zanzi D
- Zeitnitz C
- Zemaityte G
- Zemla A
- Zeng JC
- Zeng Q
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- Zerwas D
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- Zhemchugov A
- Zhou B
- Zhou C
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- Zhou N
- Zhou Y
- Zhu CG
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- Zhuang X
- Zhukov K
- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
- Zimmermann S
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- Zinser M
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- Zivkovic L
- Zobernig G
- Zoccoli A
- Zou R
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- Zwalinski L
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2017
- Field of study
Inclusive isolated-photon production in pp collisions at a centre-of-mass energy of 13TeVis studied with the ATLAS detector at the LHC using a data set with an integrated luminosity of 3.2fbâ1. The cross section is measured as a function of the photon transverse energy above 125GeVin different regions of photon pseudorapidity. Next-to-leading-order perturbative QCD and Monte Carlo event-generator predictions are compared to the cross-section measurements and provide an adequate description of the data
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