5 research outputs found

    Potentiels et leviers pour dĂ©velopper la production et l’utilisation des protĂ©agineux dans le cadre d’une agriculture durable en Bourgogne

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    A multi-partners strategy is engaged at level of Burgundy-France territory, to evaluate potentials and identify levers for the development of a chain from production to uses of grain legumes. The analysis of genotype x environment interaction and climatic factors is supported by a second year of field trials of grain legumes varieties (pea and faba bean of spring or winter sowing types. The statistical analysis of climatic data over the 1961-2009 period, has allowed to build Burgundy maps of freezing risk and late spring heat stress risk and we are able to suggest pea or faba bean genotypes, better adapted to the region. The sustainability of cropping systems involving or not grain legumes was evaluated according several criteria (agronomy, energy and other input, work organisation). It has confirmed the positive effect of inserting grain legumes, on the reduction (i) of N fertiliser, energy and pesticide uses, (ii) for easier weed control (iii) on the economic bilan assessed over whole cropping system. On 2 sites, « in situ » most measurement of N2Oemissions by soils containing grain legume crop residues were higher than those containing cereal residues. Offering to farmers varieties with good level of stress resistance and good productivity will be a key point for the development of grain legume crops. The economic analysis has identified the potential value of developing contracts between produces and collectors which will secure prices and market. The technical development of a high quality “chain” and its promotion may be valuable provided efforts on traceabilty and on labelling.Une dĂ©marche multi-partenaires est engagĂ©e sur le territoire de la rĂ©gion Bourgogne, pour Ă©valuer les potentiels et identifier des leviers au dĂ©veloppement d’une filiĂšre protĂ©agineuse. L’analyse des interactions gĂ©notype x environnement et des facteurs climatiques est appuyĂ©e par une deuxiĂšme annĂ©e d’expĂ©rimentation variĂ©tale de protĂ©agineux (pois et fĂ©veroles d’hiver et de printemps). Une Ă©tude frĂ©quentielle sur la pĂ©riode 1961-2009 a permis de cartographier les risques de gel hivernal et de fortes chaleurs en fin de cycle cultural en Bourgogne et nous pouvons proposer des variĂ©tĂ©s de pois et de fĂ©veroles mieux adaptĂ©es Ă  la rĂ©gion. Le volet d’évaluation multicritĂšres de la durabilitĂ© des systĂšmes de culture bourguignons, comparant des systĂšmes avec et sans protĂ©agineux, a permis de confirmer et de quantifier l’intĂ©rĂȘt de l’insertion de protĂ©agineux, qui passe notamment par une diminution de l’IFT moyen et des doses d’azote, une augmentation de la robustesse Ă©conomique (Ă©conomie d’engrais azotĂ©s et Ă©nergie fossile sur l’ensemble de la rotation), la diversification des rotations en offrant de nouvelles possibilitĂ©s de gestion des adventices. Sur 2 sites, le volet « environnemental » a montrĂ© en conditions « in situ », que les Ă©missions de N2O par les sols contenant des rĂ©sidus de pois ne sont en gĂ©nĂ©ral pas supĂ©rieures Ă  celles des sols contenant des rĂ©sidus de cĂ©rĂ©ales. La proposition de variĂ©tĂ©s tolĂ©rantes aux principaux stress en culture et de bonne productivitĂ© sera une clef essentielle du dĂ©veloppement des cultures protĂ©agineuses. L’analyse Ă©conomique a identifiĂ© un intĂ©rĂȘt du dĂ©veloppement de la contractualisation dans la filiĂšre et de la mise en place et de la promotion d’une filiĂšre de qualitĂ©, en accentuant les exigences en matiĂšre de traçabilitĂ© et d’étiquetage

    The burden of mild asthma: Clinical burden and healthcare resource utilisation in the NOVELTY study

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    Background: Patients with mild asthma represent a substantial proportion of the population with asthma, yet there are limited data on their true burden of disease. We aimed to describe the clinical and healthcare resource utilisation (HCRU) burden of physician-assessed mild asthma.Methods: Patients with mild asthma were included from the NOVEL observational longiTudinal studY (NOVELTY; NCT02760329), a global, 3-year, real-world prospective study of patients with asthma and/or chronic obstructive pulmonary disease from community practice (specialised and primary care). Diagnosis and severity were based on physician discretion. Clinical burden included physician-reported exacerbations and patient-reported measures. HCRU included inpatient and outpatient visits.Results: Overall, 2004 patients with mild asthma were included; 22.8% experienced ≄1 exacerbation in the previous 12 months, of whom 72.3% experienced ≄1 severe exacerbation. Of 625 exacerbations reported, 48.0% lasted >1 week, 27.7% were preceded by symptomatic worsening lasting >3 days, and 50.1% required oral corticosteroid treatment. Health status was moderately impacted (St George's Respiratory Questionnaire score: 23.5 [standard deviation ± 17.9]). At baseline, 29.7% of patients had asthma symptoms that were not well controlled or very poorly controlled (Asthma Control Test score <20), increasing to 55.6% for those with ≄2 exacerbations in the previous year. In terms of HCRU, at least one unscheduled ambulatory visit for exacerbations was required by 9.5% of patients, including 9.2% requiring ≄1 emergency department visit and 1.1% requiring ≄1 hospital admission.Conclusions: In this global sample representing community practice, a significant proportion of patients with physician-assessed mild asthma had considerable clinical burden and HCRU

    Treatable traits in the NOVELTY study

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    CorrigendumVolume 27, Issue 12, Respirology, pages: 1095-1095. First Published online: November 6, 2022 10.1111/resp.14406International audienceAsthma and chronic obstructive pulmonary disease (COPD) are two prevalent and complex diseases that require personalized management. Although a strategy based on treatable traits (TTs) has been proposed, the prevalence and relationship of TTs to the diagnostic label and disease severity established by the attending physician in a real-world setting are unknown. We assessed how the presence/absence of specific TTs relate to the diagnosis and severity of 'asthma', 'COPD' or 'asthma + COPD'

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