A Bayesian screening approach for hepatocellular carcinoma using multiple longitudinal biomarkers

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142917/1/biom12717.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/142917/2/biom12717-sup-0001-SuppData.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/142917/3/biom12717_am.pd

Band gap engineering by Bi intercalation of graphene on Ir(111)

We report on the structural and electronic properties of a single bismuth layer intercalated underneath a graphene layer grown on an Ir(111) single crystal. Scanning tunneling microscopy (STM) reveals a hexagonal surface structure and a dislocation network upon Bi intercalation, which we attribute to a $\sqrt{3}\times\sqrt{3}R30{\deg}$ Bi structure on the underlying Ir(111) surface. Ab-initio calculations show that this Bi structure is the most energetically favorable, and also illustrate that STM measurements are most sensitive to C atoms in close proximity to intercalated Bi atoms. Additionally, Bi intercalation induces a band gap ($E_g=0.42\,$eV) at the Dirac point of graphene and an overall n-doping ($\sim 0.39\,$eV), as seen in angular-resolved photoemission spectroscopy. We attribute the emergence of the band gap to the dislocation network which forms favorably along certain parts of the moir\'e structure induced by the graphene/Ir(111) interface.Comment: 5 figure

Planning the Follow-Up of Patients with Stable Chronic Coronary Artery Disease

Enfermedad arterial coronaria crónica; Análisis longitudinal; Planificar el seguimientoMalaltia arterial coronària crònica; Anàlisi longitudinal; Planificar el seguimentChronic coronary artery disease; Longitudinal analysis; Planning the follow-upCardiovascular disease remains the leading cause of death among Europeans, Americans, and around the world. In addition, the prevalence of coronary artery disease (CAD) is increasing, with the highest number of hospital visits, hospital readmissions for patients with decompensated heart failure, and a high economic cost. It is, therefore, a priority to try to plan the follow-up of patients with stable chronic CAD (scCAD) in relation to the published data, experience, and new technology that we have today. Planning the follow-up of patients with scCAD goes beyond the information provided by clinical management guidelines. It requires understanding the importance of a cross-sectional and longitudinal analysis in the clinical history of scCAD, because it has an impact on the cost of healthcare in relation to mortality, economic factors, and the burden of medical consultations. Using the data provided in this work facilitates and standardizes the clinical follow-up of patients with scCAD, and following the marked line makes the work for the clinical physician much easier, by including most clinical possibilities and actions to consider. The follow-up intervals vary according to the clinical situation of each patient and can be highly variable. In addition, the ability to properly study patients with imaging techniques, to stratify at different levels of risk, helps plan the intervals during follow-up. Given the complexity of coronary artery disease and the diversity of clinical cases, more studies are required in the future focused on improving the planning of follow-up for patients with scCAD. The perspective and future direction are related to the valuable utility of integrated imaging techniques in clinical follow-up.This research received no external funding

Editorial: hepatocellular carcinoma – a rare complication of hepatic venous outflow tract obstruction

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111131/1/apt13198.pd