376 research outputs found
Effective Rheology of Bubbles Moving in a Capillary Tube
- Author
- Abelev B
- Adam J
- Adamova D
- Adare AM
- Aggarwal MM
- Agocs AG
- Agostinelli A
- Ahammed Z
- Ahmad N
- Ahn SU
- Akindinov A
- Alaniz EC
- Aleksandrov D
- Alessandro B
- Alici A
- Alkin A
- Alme J
- Alt T
- Altini V
- Altinpinar S
- Altsybeev I
- Andrei C
- Andronic A
- Anguelov V
- Anielski J
- Anson C
- Anticic T
- Antinori F
- Antonioli P
- Aphecetche L
- Appelshauser H
- Arbor N
- Arcelli S
- Arend A
- Armesto N
- Arnaldi R
- Aronsson T
- Arsene IC
- Arslandok M
- Asryan A
- Augustinus A
- Averbeck R
- Avina EA
- Awes TC
- Aysto J
- Azmi MD
- Bach M
- Badala A
- Baek YW
- Bailhache R
- Baillie OV
- Bala R
- Balbastre GC
- Baldisseri A
- Baldit A
- Ban J
- Baral RC
- Barbera R
- Bari DD
- Barile F
- Barnafoldi GG
- Barnby LS
- Barret V
- Barros GOVD
- Barroso VC
- Bartke J
- Basile M
- Bastid N
- Bathen B
- Batigne G
- Batyunya B
- Baumann C
- Bearden IG
- Beck H
- Belikov I
- Bellini F
- Bellwied R
- Belmont-Moreno E
- Bencedi G
- Beole S
- Berceanu I
- Bercuci A
- Berdnikov Y
- Berenyi D
- Bergmann C
- Berzano D
- Betev L
- Bhasin A
- Bhati AK
- Bianchi L
- Bianchi N
- Bianchin C
- Bielcik J
- Bielcikova J
- Bjelogrlic S
- Blanco F
- Blanco F
- Blau D
- Blume C
- Boccioli M
- Bock N
- Bogdanov A
- Boggild H
- Bogolyubsky M
- Boldizsar L
- Bombara M
- Book J
- Borel H
- Borissov A
- Bornec YL
- Bose S
- Bossu F
- Botje M
- Bottger S
- Boyer B
- Braidot E
- Braun-Munzinger P
- Bregant M
- Breitner T
- Browning TA
- Broz M
- Brun R
- Bruna E
- Bruno GE
- Budnikov D
- Buesching H
- Bufalino S
- Bugaiev K
- Busch O
- Bustamante RTJ
- Buthelezi Z
- Caffarri D
- Cahuantzi MR
- Cai X
- Caines H
- Camerini P
- Carena F
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- Carminati F
- Caro AD
- Castellanos JC
- Castro XS
- Casula EAR
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- Chawla I
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- Chinellato DD
- Chochula P
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- Christensen CH
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- Chujo T
- Chung SU
- Cicalo C
- Cifarelli L
- Cindolo F
- Cleymans J
- Coccetti F
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- Collaboration ALICE
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- Zampolli C
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- Zetina LM
- Zgura IS
- Zhalov M
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- Zimmermann A
- Zinovjev G
- Zoccarato Y
- Zynovyev M
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 16/03/2012
- Field of study
We calculate the average volumetric flux versus pressure drop of bubbles
moving in a single capillary tube with varying diameter, finding a square-root
relation from mapping the flow equations onto that of a driven overdamped
pendulum. The calculation is based on a derivation of the equation of motion of
a bubble train from considering the capillary forces and the entropy production
associated with the viscous flow. We also calculate the configurational
probability of the positions of the bubbles.Comment: 4 pages, 1 figur
Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
- Author
- Akdemir KC
- Alvarez EG
- Alvarez EG
- Ardeljan D
- Baez-Ortega A
- Beroukhim R
- Beroukhim R
- Blanco MG
- Bolli N
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- Boutros PC
- Bowtell DDL
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- Burns KH
- Butler A
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- Chong Z
- Contino G
- Cortés-Ciriano I
- Demeulemeester J
- Dentro SC
- Detering H
- Dueso-Barroso A
- Dunford AJ
- Edwards PA
- Edwards PA
- Estivill X
- Etemadmoghadam D
- Feuerbach L
- Fink JL
- Fitzgerald RC
- Frenkel-Morgenstern M
- Garcia-Souto D
- Garsed DW
- Gerstein M
- Gerstein M
- Gordenin DA
- Haan D
- Haber JE
- Hess JM
- Hutter B
- Imielinski M
- Jones DTW
- Ju YS
- Ju YS
- Kazanov MD
- Kazazian HH
- Klimczak LJ
- Koh Y
- Korbel JO
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- Lee EA
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- Li Y
- Li Y
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- Macintyre G
- Markowetz F
- Martincorena I
- Martincorena I
- Martinez-Fundichely A
- Maura F
- Meyerson M
- Miyano S
- Monlong J
- Nakagawa H
- Navarro FCP
- Navarro FCP
- Ossowski S
- Park PJ
- Park PJ
- Pearson JV
- Puiggròs M
- Puiggròs M
- Raine KM
- Roberts ND
- Rodriguez-Castro J
- Rodriguez-Martin B
- Santamarina M
- Schumacher SE
- Supek F
- Temes J
- Tojo M
- Torrents D
- Van Loo P
- Wala JA
- Waszak SM
- Wedge DC
- Weischenfeldt J
- Zamora J
- Zumalave S
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/06/2023
- Field of study
Correction to: Nature Genetics https://doi.org/10.1038/s41588-019-0562-0, published online 05 February 2020
First measurement of the |t|-dependence of coherent J/ψ photonuclear production
- Author
- Acharya S
- Acosta FT
- Adam J
- Adamova D
- Adler A
- Adolfsson J
- Aggarwal MM
- Agnello M
- Agrawal N
- Ahammed Z
- Ahn SU
- Aiola S
- Akindinov A
- Al-Turany M
- Alam SN
- Albuquerque DSD
- Aleksandrov D
- Alessandro B
- Alfanda HM
- Alfaro Molina R
- Ali Y
- Alici A
- Alkin A
- Alme J
- Alt T
- Altenkamper L
- Altsybeev I
- Anaam MN
- Andrei C
- Andreou D
- Andrews HA
- Andronic A
- Angeletti M
- Anguelov V
- Anson C
- Anticic T
- Antinori F
- Antonioli P
- Anwar R
- Apadula N
- Aphecetche L
- Appelshaeuser H
- Arcelli S
- Arnaldi R
- Arratia M
- Arsene IC
- Arslandok M
- Augustinus A
- Averbeck R
- Azmi MD
- Badala A
- Baek YW
- Bagnasco S
- Bailhache R
- Baillie O Villalobos
- Bala R
- Balbastre G Conesa
- Baldisseri A
- Ball M
- Baral RC
- Barbano AM
- Barbera R
- Barile F
- Barioglio L
- Barnafoeldi GG
- Barnby LS
- Barret V
- Barroso V Chibante
- Bartalini P
- Barth K
- Bartsch E
- Bastid N
- Basu S
- Batigne G
- Batyunya B
- Batzing PC
- Bazo Alba JL
- Bearden IG
- Beck H
- Bedda C
- Behera NK
- Belikov I
- Bellini F
- Bello Martinez H
- Bellwied R
- Beltran LGE
- Belyaev V
- Bencedi G
- Beole S
- Bercuci A
- Berdnikov Y
- Berenyi D
- Bertens RA
- Berzano D
- Betev L
- Bhaduri PP
- Bhasin A
- Bhat IR
- Bhatt H
- Bhattacharjee B
- Bhom J
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- Wilkinson J
- Willems GA
- Williams MCS
- Willsher E
- Windelband B
- Witt WE
- Xu R
- Yalcin S
- Yamakawa K
- Yano S
- Yin Z
- Yokoyama H
- Yoo I-K
- Yoon JH
- Yuan S
- Yurchenko V
- Zaccolo V
- Zaman A
- Zampolli C
- Zanoli HJC
- Zardoshti N
- Zarochentsev A
- Zavada P
- Zaviyalov N
- Zbroszczyk H
- Zhalov M
- Zhang X
- Zhang Y
- Zhang Z
- Zhao C
- Zherebchevskii V
- Zhigareva N
- Zhou D
- Zhou Y
- Zhou Z
- Zhu H
- Zhu J
- Zhu Y
- Zichichi A
- Zimmermann MB
- Zinovjev G
- Zmeskal J
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
The first measurement of the cross section for coherent J/ψ photoproduction as a function of |t|, the square of the momentum transferred between the incoming and outgoing target nucleus, is presented. The data were measured with the ALICE detector in ultra-peripheral Pb–Pb collisions at a centre-of-mass energy per nucleon pair sNN=5.02TeV with the J/ψ produced in the central rapidity region |y|<0.8, which corresponds to the small Bjorken-x range (0.3−1.4)×10−3.
The measured |t|-dependence is not described by computations based only on the Pb nuclear form factor, while the photonuclear cross section is better reproduced by models including shadowing according to the leading-twist approximation, or gluon-saturation effects from the impact-parameter dependent Balitsky–Kovchegov equation. These new results are therefore a valid tool to constrain the relevant model parameters and to investigate the transverse gluonic structure at very low Bjorken-x.publishedVersio
Alignment of the ALICE Inner Tracking System with cosmic-ray tracks
- Author
- Aamodt K
- Abel N
- Abeysekara U
- Adamova D
- Aggarwal M
- Agocs AG
- Ahammed Z
- Ahmad A
- Ahmad N
- Ahn SU
- Akimoto R
- Akindinov A
- Aleksandrov D
- Alessandro B
- Alici A
- Alme J
- Alt T
- Altini V
- Altinpinar S
- Andrei C
- Andronic A
- Anelli G
- Angelov V
- Anson C
- Anticic T
- Antinori F
- Antinori S
- Antipin K
- Antonczyk D
- Antonioli P
- Anzo A
- Aphecetche L
- Appelshauser H
- Arcelli S
- Arceo R
- Arend A
- Armesto N
- Arnaldi R
- Aronsson T
- Arsene IC
- Asryan A
- Augustinus A
- Averbeck R
- Avina EA
- Awes TC
- Aysto J
- Azmi MD
- Bablok S
- Bach M
- Badala A
- Baek YW
- Bagnasco S
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- Barroso VC
- Bartke J
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- Belmont-Moreno E
- Belogianni A
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- Berceanu I
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- Berdermann E
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- Bhasin A
- Bhati AK
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- Publication date
- 01/01/2010
- Field of study
37 pages, 15 figures, revised version, accepted by JINSTALICE (A Large Ion Collider Experiment) is the LHC (Large Hadron Collider) experiment devoted to investigating the strongly interacting matter created in nucleus-nucleus collisions at the LHC energies. The ALICE ITS, Inner Tracking System, consists of six cylindrical layers of silicon detectors with three different technologies; in the outward direction: two layers of pixel detectors, two layers each of drift, and strip detectors. The number of parameters to be determined in the spatial alignment of the 2198 sensor modules of the ITS is about 13,000. The target alignment precision is well below 10 micron in some cases (pixels). The sources of alignment information include survey measurements, and the reconstructed tracks from cosmic rays and from proton-proton collisions. The main track-based alignment method uses the Millepede global approach. An iterative local method was developed and used as well. We present the results obtained for the ITS alignment using about 10^5 charged tracks from cosmic rays that have been collected during summer 2008, with the ALICE solenoidal magnet switched off.Peer reviewe
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
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- Castillo-Lorente E
- Castillo-Lorente E
- Catalan M
- Catalán RM
- Catena E
- Catena E
- Cauwenberghs H
- Cavalcanti D
- Cavalheiro AM
- Cavalier E
- Cavicchi FZ
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- Cengiz M
- Ceriani R
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- Champigneulle B
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- Chao A
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- Chaouat M
- Charitidou E
- Charpentier C
- Charpentier J
- Charron C
- Chatelon J
- Chaudhari HK
- Chaussard M
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- Chelly J
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- Cheng CC
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- Chernyshuk S
- Chevret S
- Chhor V
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- Chiappa C
- Chiou KR
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- Chiu LC
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- Chiurazzi C
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- Cho Y
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- Cholley B
- Chondropoulos S
- Chou W
- Chouris I
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- Chumaev A
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- Citerio G
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- Clavel M
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- Clermont G
- Cleyet M
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- Colaprico A
- Colino L
- Collange O
- Colombo A
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- Colson P
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- Constan A
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- Conte V
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- Contreras KM
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- Cordeiro CP
- Cordero M
- Cordolcini V
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- Cordón J
- Corona A
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- Corradi F
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- Cunha MM
- Curiel-Balsera E
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- Curinga M
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- D'Arsigny C
- da Silva SL
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- Dalhuisen A
- Dalorzo M
- Damas P
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- Damås JK
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- David H
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- Day A
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- De Brito-Ashurst I
- De Cassai A
- De Freitas FF
- De Gasperi A
- de Hoyos EA
- De la Calle-Pedrosa N
- de la Fuente MV
- De La Fuente-Martos C
- De La Fuente-Martos C
- De La Rica AS
- De la Torre MA
- De Maglie M
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- de Molina FJ
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- De Pascale G
- De Rosa S
- De Sanctis F
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- De Sousa I
- de Vera AP
- de Wilde W
- De Zani D
- Deblier I
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- Del Moral OL
- Del Olmo R
- Del Rosario CG
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- Delgado MJ
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- Di Gravio V
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- Dimopoulou IK
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- Elbers PW
- Elgendy M
- Eliet J
- Emmanuel J
- Emmerich M
- Encina B
- Endacott R
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- Engelberts D
- ENVIN-HELICS Study Group
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- Esteban A
- Estella A
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- Fave G
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- Feliot E
- Ferez MA
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- Fernandez R
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- Fernández-Ortega JF
- Ferraz AB
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- Ferri F
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- Fiks T
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- Fileković S
- Filho CA
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- FINNRESUSCI Study Group
- Fischer G
- Fleischmann E
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- Fontaiña LP
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- Frithiof R
- Fritz C
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- Fromentin M
- Frontera PR
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- Gavrychenko D
- Gayat E
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- Georgopoulos D
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- GETGAG Working Group
- GETGAG/SEMICYUC
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- Giesinger RE
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- Hernández A
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- Hernández-Tejedor A
- Herpain A
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- Ibsen M
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- Ignacio ML
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- Imanaka H
- Inaloo S
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- IPREA Study Group
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- Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group
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- Jayasinghe S
- Jean-Baptiste S
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- Jensen JU
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- Jovaisa T
- JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group
- Juan WC
- Juanas CA
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- Kolnikova I
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- Kumari BK
- Kumbamu A
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- Lichtenstein D
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- Limuti R
- Lin KC
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- Lischinsky A
- Lissonde F
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- Liu CP
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- Lobo-Civico A
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- Lombardo MD
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- Lopez-Gude MJ
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- Madueño VP
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- Maghsoudi B
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- Maistry N
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- Martín-Loeches I
- Martín-Loeches I
- Martínez F
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- Martínez M
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- Martínez MV
- Martínez NA
- Martínez-Carmona JF
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- Mejías CR
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- Mercat A
- Mercat A
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- Mergulhão PJ
- Merino-Vega D
- Messenger D
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- Midwinter MJ
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- Miguelena PR
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- Vincent JL
- Vinje LJ
- Vinsonneau C
- Vitaller S
- Vittone F
- Vogelaers D
- Voiriot G
- Volker T
- Volta CA
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- Vourli S
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- Welters I
- Wetz A
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- Wiesner O
- Wijayatilake DS
- Wildenberg L
- Wilks M
- Wilson ME
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- WIND study group
- Winder-Rhodes S
- Witter T
- Wolf M
- Wolff M
- Wong Y
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- Xie Z
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- Xini A
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- Yaguchi A
- Yamaguchi O
- Yamaguchi O
- Yamaguchi Y
- Yamaguchi Y
- Yamamoto H
- Yamamoto N
- Yaman G
- Yamashita K
- Yamazaki A
- Yan WW
- Yan WW
- Yang JH
- Yang JS
- Yang YL
- Yasuda H
- Yatabe T
- Yebenes JC
- Yeh YC
- Yemets H
- Yergaliyeva A
- Yılmaz G
- Yilmazer F
- Yodice P
- Yokoyama M
- Yonis H
- Yonis H
- Yonis H
- Yoon SZ
- Yoruk F
- Yoshida K
- Yoshida T
- Yoshida T
- Yoshida T
- Yoshida T
- Yoshihiro S
- Yoshitake E
- You KM
- Youn AM
- Young A
- Yu KM
- Yumoto T
- Yuzawa J
- Yuzawa J
- Zabaletta WJ
- Zabini D
- Zahorec M
- Zaien I
- Zakynthinos S
- Zanello M
- Zani D
- Zarantonello F
- Zayas B
- Zepeda EM
- Zeroual N
- Zerva L
- Zhang J
- Zhou JC
- Zhou JC
- Zhou JX
- Zhovnir V
- Zibandah N
- Zijlstra F
- Zimmerman J
- Zogheib E
- Zogheib E
- Zogheib E
- Zullino V
- Zwaag J
- Zýková I
- Álvarez JT
- Álvarez-Lerma F
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
Combination of searches for heavy spin-1 resonances using 139 fb−1 of proton-proton collision data at s = 13 TeV with the ATLAS detector
- Author
- Aad G
- Aakvaag E
- Abbott B
- Abeling K
- Abicht NJ
- Abidi SH
- Aboelela M
- Aboulhorma A
- Abramowicz H
- Abreu H
- Abulaiti Y
- Acharya BS
- Ackermann A
- Adam Bourdarios C
- Adamczyk L
- Addepalli SV
- Addison MJ
- Adelman J
- Adiguzel A
- Adye T
- Affolder AA
- Afik Y
- Agaras MN
- Agarwala J
- Aggarwal A
- Agheorghiesei C
- Ahmad A
- Ahmadov F
- Ahmed WS
- Ahuja S
- Ai X
- Aielli G
- Aikot A
- Ait Tamlihat M
- Aitbenchikh B
- Aizenberg I
- Akbiyik M
- Akimov AV
- Akiyama D
- Akolkar NN
- Aktas S
- Al Khoury K
- Alberghi GL
- Albert J
- Albicocco P
- Albouy GL
- Alderweireldt S
- Alegria ZL
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexopoulos T
- Alfonsi F
- Algren M
- Alhroob M
- Ali B
- Ali HMJ
- Ali S
- Alibocus SW
- Aliev M
- Alimonti G
- Alkakhi W
- Allaire C
- Allbrooke BMM
- Allen JF
- Allendes Flores CA
- Allport PP
- Aloisio A
- Alonso F
- Alpigiani C
- Alvarez Estevez M
- Alvarez Fernandez A
- Alves Cardoso M
- Alviggi MG
- Aly M
- Amaral Coutinho Y
- Ambler A
- Amelung C
- Amerl M
- Ames CG
- Amidei D
- Amirie KJ
- Amor Dos Santos SP
- Amos KR
- An S
- Ananiev V
- Anastopoulos C
- Andeen T
- Anders JK
- Andrean SY
- Andreazza A
- Angelidakis S
- Angerami A
- Anisenkov AV
- Annovi A
- Antel C
- Anthony MT
- Antipov E
- Antonelli M
- Anulli F
- Aoki M
- Aoki T
- Aparisi Pozo JA
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- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- Springer Nature
- Publication date
- 19/04/2024
- Field of study
A combination of searches for new heavy spin-1 resonances decaying into different pairings of W, Z, or Higgs bosons, as well as directly into leptons or quarks, is presented. The data sample used corresponds to 139 fb−1 of proton-proton collisions at
= 13 TeV collected during 2015–2018 with the ATLAS detector at the CERN Large Hadron Collider. Analyses selecting quark pairs (qq, bb,
, and tb) or third-generation leptons (τν and ττ) are included in this kind of combination for the first time. A simplified model predicting a spin-1 heavy vector-boson triplet is used. Cross-section limits are set at the 95% confidence level and are compared with predictions for the benchmark model. These limits are also expressed in terms of constraints on couplings of the heavy vector-boson triplet to quarks, leptons, and the Higgs boson. The complementarity of the various analyses increases the sensitivity to new physics, and the resulting constraints are stronger than those from any individual analysis considered. The data exclude a heavy vector-boson triplet with mass below 5.8 TeV in a weakly coupled scenario, below 4.4 TeV in a strongly coupled scenario, and up to 1.5 TeV in the case of production via vector-boson fusion
Measurement and interpretation of same-sign W boson pair production in association with two jets in pp collisions at s = 13 TeV with the ATLAS detector
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- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- Springer Nature
- Publication date
- 01/04/2024
- Field of study
This paper presents the measurement of fducial and diferential cross sections for both the inclusive and electroweak production of a same-sign W-boson pair in association with two jets (W±W±jj) using 139 fb−1 of proton-proton collision data recorded at a centre-of-mass energy of √s = 13 TeV by the ATLAS detector at the Large Hadron Collider. The analysis is performed by selecting two same-charge leptons, electron or muon, and at least two jets with large invariant mass and a large rapidity diference. The measured fducial cross sections for electroweak and inclusive W±W±jj production are 2.92 ± 0.22 (stat.) ± 0.19 (syst.)fb and 3.38±0.22 (stat.)±0.19 (syst.)fb, respectively, in agreement with Standard Model predictions. The measurements are used to constrain anomalous quartic gauge couplings by extracting 95% confdence level intervals on dimension-8 operators. A search for doubly charged Higgs bosons H±± that are produced in vector-boson fusion processes and decay into a same-sign W boson pair is performed. The largest deviation from the Standard Model occurs for an H±± mass near 450 GeV, with a global signifcance of 2.5 standard deviations
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- The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium View Correspondence (jump link)
- Thiessen
- Thomas
- Thomas
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- wi Futreal
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- xv Luxton
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- xy Visakorpi
- xz Whitaker
- Y. -E. ot
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- Y. uz
- Y. vr
- Y. wt
- Y. yc
- ya Al-Ahmadie
- Yachida
- Yamaguchi
- Yamaguchi T. N. k
- Yamamoto
- Yamaue
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- Yang
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- Yang
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- z ah
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- zd Gershenwald
- Zenklusen
- Zeps
- zf Ghossein
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang H. b
- Zhao
- Zheng
- Zhou
- Zhou
- Zhu
- Zhu
- zi zj
- zm Jayaseelan
- Zou
- Zou
- zt Kim
- zw Lewis
- Ó. A. th
- Ø. sk
- Publication venue
- Publication date
- 11/12/2019
- Field of study
Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale(1-3). Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4-5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter(4); identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation(5,6); analyses timings and patterns of tumour evolution(7); describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity(8,9); and evaluates a range of more-specialized features of cancer genomes(8,10-18).Peer reviewe
Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020
- Author
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Background The health risks associated with moderate alcohol consumption continue to be debated. Small amounts of alcohol might lower the risk of some health outcomes but increase the risk of others, suggesting that the overall risk depends, in part, on background disease rates, which vary by region, age, sex, and year. Methods For this analysis, we constructed burden-weighted dose–response relative risk curves across 22 health outcomes to estimate the theoretical minimum risk exposure level (TMREL) and non-drinker equivalence (NDE), the consumption level at which the health risk is equivalent to that of a non-drinker, using disease rates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020 for 21 regions, including 204 countries and territories, by 5-year age group, sex, and year for individuals aged 15–95 years and older from 1990 to 2020. Based on the NDE, we quantified the population consuming harmful amounts of alcohol. Findings The burden-weighted relative risk curves for alcohol use varied by region and age. Among individuals aged 15–39 years in 2020, the TMREL varied between 0 (95% uncertainty interval 0–0) and 0·603 (0·400–1·00) standard drinks per day, and the NDE varied between 0·002 (0–0) and 1·75 (0·698–4·30) standard drinks per day. Among individuals aged 40 years and older, the burden-weighted relative risk curve was J-shaped for all regions, with a 2020 TMREL that ranged from 0·114 (0–0·403) to 1·87 (0·500–3·30) standard drinks per day and an NDE that ranged between 0·193 (0–0·900) and 6·94 (3·40–8·30) standard drinks per day. Among individuals consuming harmful amounts of alcohol in 2020, 59·1% (54·3–65·4) were aged 15–39 years and 76·9% (73·0–81·3) were male. Interpretation There is strong evidence to support recommendations on alcohol consumption varying by age and location. Stronger interventions, particularly those tailored towards younger individuals, are needed to reduce the substantial global health loss attributable to alcohol. Funding Bill & Melinda Gates Foundation
Flow Dominance and Factorization of Transverse Momentum Correlations in Pb-Pb Collisions at the LHC
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- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2017
- Field of study
We present the first measurement of the two-particle transverse momentum differential correlation function, P2≡ ΔpTΔpT/ pT2, in Pb-Pb collisions at sNN=2.76 TeV. Results for P2 are reported as a function of the relative pseudorapidity (Δη) and azimuthal angle (Δφ) between two particles for different collision centralities. The Δφ dependence is found to be largely independent of Δη for |Δη|≥0.9. In the 5% most central Pb-Pb collisions, the two-particle transverse momentum correlation function exhibits a clear double-hump structure around Δφ=π (i.e., on the away side), which is not observed in number correlations in the same centrality range, and thus provides an indication of the dominance of triangular flow in this collision centrality. Fourier decompositions of P2, studied as a function of the collision centrality, show that correlations at |Δη|≥0.9 can be well reproduced by a flow ansatz based on the notion that measured transverse momentum correlations are strictly determined by the collective motion of the system
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