66 research outputs found
UNUSUAL NEST AND NESTLING APPROPRIATION BY THE EARED DOVE (ZENAIDA AURICULATA)
Abstract ∙ We report a case of interspecific nest appropriation by the Eared Dove (Zenaida auriculata) on a nest of the Creamy‐bellied Thrush (Turdus amaurochalinus). The usurpation attempt resulted in the death of both nestlings, including a parasitic cowbird, despite forceful attempts by the thrushes to retake their nest and repeated attempts by the dove to feed the nestlings. We believe that the loss of the dove offspring from a nest in a neighboring tree could have triggered this behavior, which may be a hormonal byproduct caused by the recent loss of their own offspring, similar to what has been observed in Emperor Penguins (Aptenodytes fosteri).Resumen ∙ Inusual apropiación de nido y pichones por parte de la Paloma Torcaza (Zenaida auriculata) Reportamos un caso de apropiación interespecífica de nido en donde una Torcaza (Zenaida auriculata) usurpa el nido de un Zorzal Chalchalero (Turdus amaurochalinus). Ambos pichones, incluido un pichón parásito de cría, resultaron muertos tras la usurpación, a pesar de los enérgicos esfuerzos de los zorzales por recuperar el nido y de los repetidos intentos de la paloma para alimentar los pichones. Creemos que la Torcaza perdió sus propios pichones cerca del nido de zorzal y esto motivó la usurpación. Atribuimos el falso reconocimiento de los pichones a un subproducto hormonal causado por la pérdida de sus propios pichones, similar a lo observado en el Pingüino Emperador (Aptenodytes fosteri)
La colección de huevos "Pablo Girard" del Museo de La Plata
Se presenta información sobre la colección de huevos "Pablo Girard" que forma parte de la Colección Ornitológica del Museo de La Plata (División Zoología de Vertebrados, Facultad de Ciencias Naturales y Museo, Universidad Nacional de La Plata). El Sr. Pablo Girard fue un naturalista alemán radicado en la provincia de Tucumán entre las décadas de 1920 y 1940. La donación de esta colección privada al Museo de La Plata generó un importante aporte a la colección de huevos preexistente, ya que incluye información valiosa sobre 18 Órdenes y 38 Familias que nidifican en el noroeste de Argentina, particularmente en la provincia de Tucumán, sur de Salta y noroeste de Santiago del Estero
New avian hosts for Taphropiestes plaumanni (Coleoptera: Cavognathidae) and the record of nestlings skin lesions and body deterioration associated with parasitism
Abstract We collected data during three consecutive breeding seasons (2015-2018) to assess the effects of Taphropiestes plaumanni (Coleoptera: Cavognathidae) on its bird hosts in a native forest of central eastern Argentina. We monitored bird nests for T. plaumanni in 207 nests of Masked Gnatcatcher (Polioptila dumicola, Polioptilidae), 302 nests of Vermilion Flycatcher (Pyrocephalus rubinus, Tyrannidae), 55 nests of Blue-and-yellow Tanager (Pipraeidea bonariensis, Thraupidae), 99 nests of Small-billed Elaenia (Elaenia parvirostris, Tyrannidae), 23 nests of Yellow-browed Tyrant (Satrapa icterophrys, Tyrannidae), and other passerine species nesting in the same forest patches. We found 13 nests in which nestlings showed evidences of parasitism of which four species are new hosts for this parasite (Vermilion Flycatcher, Masked Gnatcatcher, Red-crested Cardinal Paroaria coronata, Thraupidae, and Fork-tailed Flycatcher Tyrannus savana). Skin lesions caused by T. plaumanni larvae consisted in lacerations and crusts on the belly and chest areas. In one parasitized nest of Vermilion Flycatcher and one parasitized nest of Masked Gnatcatcher we observed the death of nestlings after being parasitized. This study adds new species to the list of hosts for this parasite, reports nestling skin lesions in nests with T. plaumanni parasitism, and reports for the first time the death of parasitized nestlings
La Colección de huevos "Ronald Runnacles" del Museo de La Plata: historia y material depositado
We present information about the private egg collection "Ronald Runnacles" as part of the Ornithological Collection at the Museo de La Plata (División Zoología Vertebrados, Facultad de Ciencias Naturales y Museo, Universidad Nacional de La Plata). Mr. Ronald Runnacles was an argentine naturalist who lived in General Lavalle, Buenos Aires province. He devoted his short life to the study of birds, mainly waterbirds of central-east Argentina. He started very young to collect eggs in General Lavalle for his private egg collection, but his fieldwork was stopped prematurely at 26 years old after called of the British government to join in the World War II in 1941. He died a year later at the battle fronts in Holland. His family donated years after the complete egg collection to the Museo de La Plata, which generated a significant contribution to the existing egg collection, as it includes valuable information about 17 orders and 44 families of birds that nest in central-east Argentina.Se presenta información sobre la colección de huevos "Ronald Runnacles" queforma parte de la Colección Ornitológica del Museo de La Plata (División ZoologíaVertebrados, Facultad de Ciencias Naturales y Museo, Universidad Nacional de La Plata). ElSr. Ronald Runnacles fue un naturalista argentino radicado en la localidad de GeneralLavalle, provincia de Buenos Aires. Dedicó su corta vida al estudio de las aves,principalmente aves acuáticas de la región pampeana. Comenzó de muy joven a recolectarhuevos en la zona de General Lavalle para su colección privada, pero su trabajo de campo seinterrumpió prematuramente a sus 26 años luego de la citación del gobierno británico parasumarse a la Segunda Guerra Mundial en el año 1941. Murió un año después en los frentes debatalla en Holanda. Años después su familia donó la colección de huevos al Museo de LaPlata, la cual generó un relevante aporte a la colección de huevos preexistente, ya que incluyeinformación valiosa sobre 17 Órdenes y 44 Familias de aves que nidifican en la regiónpampeana
Measurement of the Bottom-Strange Meson Mixing Phase in the Full CDF Data Set
We report a measurement of the bottom-strange meson mixing phase \beta_s
using the time evolution of B0_s -> J/\psi (->\mu+\mu-) \phi (-> K+ K-) decays
in which the quark-flavor content of the bottom-strange meson is identified at
production. This measurement uses the full data set of proton-antiproton
collisions at sqrt(s)= 1.96 TeV collected by the Collider Detector experiment
at the Fermilab Tevatron, corresponding to 9.6 fb-1 of integrated luminosity.
We report confidence regions in the two-dimensional space of \beta_s and the
B0_s decay-width difference \Delta\Gamma_s, and measure \beta_s in [-\pi/2,
-1.51] U [-0.06, 0.30] U [1.26, \pi/2] at the 68% confidence level, in
agreement with the standard model expectation. Assuming the standard model
value of \beta_s, we also determine \Delta\Gamma_s = 0.068 +- 0.026 (stat) +-
0.009 (syst) ps-1 and the mean B0_s lifetime, \tau_s = 1.528 +- 0.019 (stat) +-
0.009 (syst) ps, which are consistent and competitive with determinations by
other experiments.Comment: 8 pages, 2 figures, Phys. Rev. Lett 109, 171802 (2012
Functionalization of Carbon Nanomaterial Surface by Doxorubicin and Antibodies to Tumor Markers
The actual task of oncology is effective treatment of cancer while causing a minimum harm to the patient. The appearance of polymer nanomaterials and technologies launched new applications and approaches of delivery and release of anticancer drugs. The goal of work was to test ultra dispersed diamonds (UDDs) and onion-like carbon (OLCs) as new vehicles for delivery of antitumor drug (doxorubicin (DOX)) and specific antibodies to tumor receptors. Stable compounds of UDDs and OLCs with DOX were obtained. As results of work, an effectiveness of functionalization was 2.94 % w/w for OLC-DOX and 2.98 % w/w for UDD-DOX. Also, there was demonstrated that UDD-DOX and OLC-DOX constructs had dose-dependent cytotoxic effect on tumor cells in the presence of trypsin. The survival of adenocarcinoma cells reduced from 52 to 28 % in case of incubation with the UDD-DOX in concentrations from 8.4–2.5 to 670–20 μg/ml and from 72 to 30 % after incubation with OLC-DOX. Simultaneously, antibodies to epidermal growth factor maintained 75 % of the functional activity and specificity after matrix-assisted pulsed laser evaporation deposition. Thus, the conclusion has been made about the prospects of selected new methods and approaches for creating an antitumor agent with capabilities targeted delivery of drugs
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. For example, a key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process versus those that measure fl ux through the autophagy pathway (i.e., the complete process including the amount and rate of cargo sequestered and degraded). In particular, a block in macroautophagy that results in autophagosome accumulation must be differentiated from stimuli that increase autophagic activity, defi ned as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (inmost higher eukaryotes and some protists such as Dictyostelium ) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the fi eld understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. It is worth emphasizing here that lysosomal digestion is a stage of autophagy and evaluating its competence is a crucial part of the evaluation of autophagic flux, or complete autophagy. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. Along these lines, because of the potential for pleiotropic effects due to blocking autophagy through genetic manipulation it is imperative to delete or knock down more than one autophagy-related gene. In addition, some individual Atg proteins, or groups of proteins, are involved in other cellular pathways so not all Atg proteins can be used as a specific marker for an autophagic process. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field
Global disparities in surgeons’ workloads, academic engagement and rest periods: the on-calL shIft fOr geNEral SurgeonS (LIONESS) study
: The workload of general surgeons is multifaceted, encompassing not only surgical procedures but also a myriad of other responsibilities. From April to May 2023, we conducted a CHERRIES-compliant internet-based survey analyzing clinical practice, academic engagement, and post-on-call rest. The questionnaire featured six sections with 35 questions. Statistical analysis used Chi-square tests, ANOVA, and logistic regression (SPSS® v. 28). The survey received a total of 1.046 responses (65.4%). Over 78.0% of responders came from Europe, 65.1% came from a general surgery unit; 92.8% of European and 87.5% of North American respondents were involved in research, compared to 71.7% in Africa. Europe led in publishing research studies (6.6 ± 8.6 yearly). Teaching involvement was high in North America (100%) and Africa (91.7%). Surgeons reported an average of 6.7 ± 4.9 on-call shifts per month, with European and North American surgeons experiencing 6.5 ± 4.9 and 7.8 ± 4.1 on-calls monthly, respectively. African surgeons had the highest on-call frequency (8.7 ± 6.1). Post-on-call, only 35.1% of respondents received a day off. Europeans were most likely (40%) to have a day off, while African surgeons were least likely (6.7%). On the adjusted multivariable analysis HDI (Human Development Index) (aOR 1.993) hospital capacity > 400 beds (aOR 2.423), working in a specialty surgery unit (aOR 2.087), and making the on-call in-house (aOR 5.446), significantly predicted the likelihood of having a day off after an on-call shift. Our study revealed critical insights into the disparities in workload, access to research, and professional opportunities for surgeons across different continents, underscored by the HDI
Erratum: Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
Interpretation: By quantifying levels and trends in exposures to risk factors and the resulting disease burden, this assessment offers insight into where past policy and programme efforts might have been successful and highlights current priorities for public health action. Decreases in behavioural, environmental, and occupational risks have largely offset the effects of population growth and ageing, in relation to trends in absolute burden. Conversely, the combination of increasing metabolic risks and population ageing will probably continue to drive the increasing trends in non-communicable diseases at the global level, which presents both a public health challenge and opportunity. We see considerable spatiotemporal heterogeneity in levels of risk exposure and risk-attributable burden. Although levels of development underlie some of this heterogeneity, O/E ratios show risks for which countries are overperforming or underperforming relative to their level of development. As such, these ratios provide a benchmarking tool to help to focus local decision making. Our findings reinforce the importance of both risk exposure monitoring and epidemiological research to assess causal connections between risks and health outcomes, and they highlight the usefulness of the GBD study in synthesising data to draw comprehensive and robust conclusions that help to inform good policy and strategic health planning
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
Summary
Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally.
Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies
have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of
the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income
countries globally, and identified factors associated with mortality.
Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to
hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis,
exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a
minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical
status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary
intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause,
in-hospital mortality for all conditions combined and each condition individually, stratified by country income status.
We did a complete case analysis.
Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital
diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal
malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome
countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male.
Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3).
Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income
countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups).
Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome
countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries;
p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients
combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11],
p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20
[1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention
(ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety
checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed
(ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of
parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65
[0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality.
Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome,
middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will
be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger
than 5 years by 2030
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