15 research outputs found
Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at √ s = 8 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abbott DC
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
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- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb−1 of √ s = 8 TeV data collected in 2012 with the ATLAS detector at the LHC. Events are required to have at least one jet with pT > 120 GeV and no leptons. Nine signal regions are considered with increasing missing transverse momentum requirements between Emiss T > 150 GeV and Emiss T > 700 GeV. Good agreement is observed between the number of events in data and Standard Model expectations. The results are translated into exclusion limits on models with either large extra spatial dimensions, pair production of weakly interacting dark matter candidates, or production of very light gravitinos in a gauge-mediated supersymmetric model. In addition, limits on the production of an invisibly decaying Higgs-like boson leading to similar topologies in the final state are presente
Pan-cancer analysis of whole genomes
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- The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium View Correspondence (jump link)
- Thiessen
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- Y. rj
- Y. rm
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- Yachida
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- z ah
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- zd Gershenwald
- Zenklusen
- Zeps
- zf Ghossein
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang H. b
- Zhao
- Zheng
- Zhou
- Zhou
- Zhu
- Zhu
- zi zj
- zm Jayaseelan
- Zou
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- Publication venue
- Publication date
- 11/12/2019
- Field of study
Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale(1-3). Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4-5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter(4); identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation(5,6); analyses timings and patterns of tumour evolution(7); describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity(8,9); and evaluates a range of more-specialized features of cancer genomes(8,10-18).Peer reviewe
Maternal dietary patterns, diet quality and micronutrient status in gestational diabetes mellitus across different economies: A review
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- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
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- Field of study
Recommended from our members
Observation of Gravitational Waves from the Coalescence of a 2.5–4.5 M <sub>⊙</sub> Compact Object and a Neutron Star
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- Wysocki DM
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- Yaala M Ben
- Yadav N
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- Yamamoto T
- Yamamoto TS
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- Yamazaki R
- Yan S
- Yan T
- Yang F
- Yang FW
- Yang KZ
- Yang Y
- Yarbrough Z
- Yasui H
- Yeh S-W
- Yelikar AB
- Yin X
- Yokoyama J
- Yokozawa T
- Yoo J
- Yu H
- Yuan S
- Yuzurihara H
- Zadrożny A
- Zanolin M
- Zeeshan M
- Zelenova T
- Zendri J-P
- Zeoli M
- Zerrad M
- Zevin M
- Zhang AC
- Zhang L
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- Zhao C
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- Zhao Yuhang
- Zheng Y
- Zhong H
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- Zhu X-J
- Zhu Z-H
- Zimmerman AB
- Zucker ME
- Zweizig J
- Publication venue
- The Astrophysical Journal Letters
- Publication date
- 26/07/2024
- Field of study
Abstract
We report the observation of a coalescing compact binary with component masses 2.5–4.5 M
⊙ and 1.2–2.0 M
⊙ (all measurements quoted at the 90% credible level). The gravitational-wave signal GW230529_181500 was observed during the fourth observing run of the LIGO–Virgo–KAGRA detector network on 2023 May 29 by the LIGO Livingston observatory. The primary component of the source has a mass less than 5 M
⊙ at 99% credibility. We cannot definitively determine from gravitational-wave data alone whether either component of the source is a neutron star or a black hole. However, given existing estimates of the maximum neutron star mass, we find the most probable interpretation of the source to be the coalescence of a neutron star with a black hole that has a mass between the most massive neutron stars and the least massive black holes observed in the Galaxy. We provisionally estimate a merger rate density of
55
−
47
+
127
Gpc
−
3
yr
−
1
for compact binary coalescences with properties similar to the source of GW230529_181500; assuming that the source is a neutron star–black hole merger, GW230529_181500-like sources may make up the majority of neutron star–black hole coalescences. The discovery of this system implies an increase in the expected rate of neutron star–black hole mergers with electromagnetic counterparts and provides further evidence for compact objects existing within the purported lower mass gap.</jats:p
Recommended from our members
Open Data from the Third Observing Run of LIGO, Virgo, KAGRA, and GEO
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- Publication venue
- The Astrophysical Journal Supplement Series
- Publication date
- 22/08/2023
- Field of study
Abstract
The global network of gravitational-wave observatories now includes five detectors, namely LIGO Hanford, LIGO Livingston, Virgo, KAGRA, and GEO 600. These detectors collected data during their third observing run, O3, composed of three phases: O3a starting in 2019 April and lasting six months, O3b starting in 2019 November and lasting five months, and O3GK starting in 2020 April and lasting two weeks. In this paper we describe these data and various other science products that can be freely accessed through the Gravitational Wave Open Science Center at https://gwosc.org. The main data set, consisting of the gravitational-wave strain time series that contains the astrophysical signals, is released together with supporting data useful for their analysis and documentation, tutorials, as well as analysis software packages.</jats:p
Search for Subsolar-Mass Binaries in the First Half of Advanced LIGO's and Advanced Virgo's Third Observing Run
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- Zanolin M
- Zeidler S
- Zelenova T
- Zendri J-P
- Zevin M
- Zhan M
- Zhang H
- Zhang J
- Zhang L
- Zhang R
- Zhang T
- Zhang Y
- Zhao C
- Zhao G
- Zhao Y
- Zhao Yue
- Zhou R
- Zhou Z
- Zhu XJ
- Zhu Z-H
- Zimmerman AB
- Zucker ME
- Zweizig J
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2022
- Field of study
We report on a search for compact binary coalescences where at least one binary component has a mass between 0.2 M and 1.0 M in Advanced LIGO and Advanced Virgo data collected between 1 April 2019 1500 UTC and 1 October 2019 1500 UTC. We extend our previous analyses in two main ways: we include data from the Virgo detector and we allow for more unequal mass systems, with mass ratio q≥0.1. We do not report any gravitational-wave candidates. The most significant trigger has a false alarm rate of 0.14 yr-1. This implies an upper limit on the merger rate of subsolar binaries in the range [220-24200] Gpc-3 yr-1, depending on the chirp mass of the binary. We use this upper limit to derive astrophysical constraints on two phenomenological models that could produce subsolar-mass compact objects. One is an isotropic distribution of equal-mass primordial black holes. Using this model, we find that the fraction of dark matter in primordial black holes in the mass range 0.2 M<1.0 M is fPBHωPBH/ωDM6%. This improves existing constraints on primordial black hole abundance by a factor of ∼3. The other is a dissipative dark matter model, in which fermionic dark matter can collapse and form black holes. The upper limit on the fraction of dark matter black holes depends on the minimum mass of the black holes that can be formed: the most constraining result is obtained at Mmin=1 M, where fDBHωDBH/ωDM0.003%. These are the first constraints placed on dissipative dark models by subsolar-mass analyses
Recommended from our members
Constraints on the Cosmic Expansion History from GWTC–3
- Author
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- Yeh S-W
- Yelikar AB
- Ying M
- Yokoyama J
- Yokozawa T
- Yoo J
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- Yuzurihara H
- Zadrożny A
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- Zhu Z-H
- Zimmerman AB
- Zucker ME
- Zweizig J
- Publication venue
- The Astrophysical Journal
- Publication date
- 07/06/2023
- Field of study
Abstract
We use 47 gravitational wave sources from the Third LIGO–Virgo–Kamioka Gravitational Wave Detector Gravitational Wave Transient Catalog (GWTC–3) to estimate the Hubble parameter H(z), including its current value, the Hubble constant H
0. Each gravitational wave (GW) signal provides the luminosity distance to the source, and we estimate the corresponding redshift using two methods: the redshifted masses and a galaxy catalog. Using the binary black hole (BBH) redshifted masses, we simultaneously infer the source mass distribution and H(z). The source mass distribution displays a peak around 34 M
⊙, followed by a drop-off. Assuming this mass scale does not evolve with the redshift results in a H(z) measurement, yielding
H
0
=
68
−
8
+
12
km
s
−
1
Mpc
−
1
(68% credible interval) when combined with the H
0 measurement from GW170817 and its electromagnetic counterpart. This represents an improvement of 17% with respect to the H
0 estimate from GWTC–1. The second method associates each GW event with its probable host galaxy in the catalog GLADE+, statistically marginalizing over the redshifts of each event’s potential hosts. Assuming a fixed BBH population, we estimate a value of
H
0
=
68
−
6
+
8
km
s
−
1
Mpc
−
1
with the galaxy catalog method, an improvement of 42% with respect to our GWTC–1 result and 20% with respect to recent H
0 studies using GWTC–2 events. However, we show that this result is strongly impacted by assumptions about the BBH source mass distribution; the only event which is not strongly impacted by such assumptions (and is thus informative about H
0) is the well-localized event GW190814.</jats:p
Recommended from our members
A Joint Fermi-GBM and Swift-BAT Analysis of Gravitational-wave Candidates from the Third Gravitational-wave Observing Run
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- Wysocki DM
- Xiao L
- Yamada T
- Yamamoto H
- Yamamoto K
- Yamamoto T
- Yamashita K
- Yamazaki R
- Yang FW
- Yang KZ
- Yang L
- Yang Y
- Yang Y-C
- Yang Yang
- Yap MJ
- Yeeles DW
- Yeh S-W
- Yelikar AB
- Ying M
- Yokoyama J
- Yokozawa T
- Yoo J
- Yoshioka T
- Yu Hang
- Yu Haocun
- Yuzurihara H
- Zadrożny A
- Zanolin M
- Zeidler S
- Zelenova T
- Zendri J-P
- Zevin M
- Zhan M
- Zhang H
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- Zhang L
- Zhang R
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- Zhao G
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- Zhao Yue
- Zhou R
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- Zhu XJ
- Zhu Z-H
- Zimmerman AB
- Zucker ME
- Zweizig J
- Publication venue
- The Astrophysical Journal
- Publication date
- 28/03/2024
- Field of study
Abstract
We present Fermi Gamma-ray Burst Monitor (Fermi-GBM) and Swift Burst Alert Telescope (Swift-BAT) searches for gamma-ray/X-ray counterparts to gravitational-wave (GW) candidate events identified during the third observing run of the Advanced LIGO and Advanced Virgo detectors. Using Fermi-GBM onboard triggers and subthreshold gamma-ray burst (GRB) candidates found in the Fermi-GBM ground analyses, the Targeted Search and the Untargeted Search, we investigate whether there are any coincident GRBs associated with the GWs. We also search the Swift-BAT rate data around the GW times to determine whether a GRB counterpart is present. No counterparts are found. Using both the Fermi-GBM Targeted Search and the Swift-BAT search, we calculate flux upper limits and present joint upper limits on the gamma-ray luminosity of each GW. Given these limits, we constrain theoretical models for the emission of gamma rays from binary black hole mergers.</jats:p
Recommended from our members
Search for Gravitational-wave Transients Associated with Magnetar Bursts in Advanced LIGO and Advanced Virgo Data from the Third Observing Run
- Author
- Abbott R
- Abe H
- Acernese F
- Ackley K
- Adhikari N
- Adhikari RX
- Adkins VK
- Adya VB
- Affeldt C
- Agarwal D
- Agathos M
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- Aggarwal N
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- Aiello L
- Ain A
- Ajith P
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- Albanesi S
- Alfaidi RA
- Allocca A
- Altin PA
- Amato A
- Anand C
- Anand S
- Ananyeva A
- Anderson SB
- Anderson WG
- Ando M
- Andrade T
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- Andrić T
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- Angelova SV
- Ansoldi S
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- Banerjee B
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- Barbieri C
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- Blackburn JK
- Blair CD
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- Bondu F
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- Bonnand R
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- Yap MJ
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- Yeh S-W
- Yelikar AB
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- Zucker ME
- Zweizig J
- Publication venue
- The Astrophysical Journal
- Publication date
- 30/04/2024
- Field of study
Abstract
Gravitational waves are expected to be produced from neutron star oscillations associated with magnetar giant flares and short bursts. We present the results of a search for short-duration (milliseconds to seconds) and long-duration (∼100 s) transient gravitational waves from 13 magnetar short bursts observed during Advanced LIGO, Advanced Virgo, and KAGRA’s third observation run. These 13 bursts come from two magnetars, SGR 1935+2154 and Swift J1818.0−1607. We also include three other electromagnetic burst events detected by Fermi-GBM which were identified as likely coming from one or more magnetars, but they have no association with a known magnetar. No magnetar giant flares were detected during the analysis period. We find no evidence of gravitational waves associated with any of these 16 bursts. We place upper limits on the rss of the integrated incident gravitational-wave strain that reach 3.6 × 10−23
/
Hz
at 100 Hz for the short-duration search and 1.1 × 10−22
/
Hz
at 450 Hz for the long-duration search. For a ringdown signal at 1590 Hz targeted by the short-duration search the limit is set to 2.3 × 10−22
/
Hz
. Using the estimated distance to each magnetar, we derive upper limits on the emitted gravitational-wave energy of 1.5 × 1044 erg (1.0 × 1044 erg) for SGR 1935+2154 and 9.4 × 1043 erg (1.3 × 1044 erg) for Swift J1818.0−1607, for the short-duration (long-duration) search. Assuming isotropic emission of electromagnetic radiation of the burst fluences, we constrain the ratio of gravitational-wave energy to electromagnetic energy for bursts from SGR 1935+2154 with the available fluence information. The lowest of these ratios is 4.5 × 103.</jats:p
All-sky, all-frequency directional search for persistent gravitational waves from Advanced LIGO's and Advanced Virgo's first three observing runs
- Author
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- Abe H
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- Zimmerman AB
- Zucker ME
- Zweizig J
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2022
- Field of study
We present the first results from an all-sky all-frequency (ASAF) search for an anisotropic stochastic gravitational-wave background using the data from the first three observing runs of the Advanced LIGO and Advanced Virgo detectors. Upper limit maps on broadband anisotropies of a persistent stochastic background were published for all observing runs of the LIGO-Virgo detectors. However, a broadband analysis is likely to miss narrowband signals as the signal-to-noise ratio of a narrowband signal can be significantly reduced when combined with detector output from other frequencies. Data folding and the computationally efficient analysis pipeline, PyStoch, enable us to perform the radiometer map-making at every frequency bin. We perform the search at 3072 HEALPix equal area pixels uniformly tiling the sky and in every frequency bin of width 1/32 Hz in the range 20-1726 Hz, except for bins that are likely to contain instrumental artefacts and hence are notched. We do not find any statistically significant evidence for the existence of narrowband gravitational-wave signals in the analyzed frequency bins. Therefore, we place 95% confidence upper limits on the gravitational-wave strain for each pixel-frequency pair, the limits are in the range (0.030-9.6)×10-24. In addition, we outline a method to identify candidate pixel-frequency pairs that could be followed up by a more sensitive (and potentially computationally expensive) search, e.g., a matched-filtering-based analysis, to look for fainter nearly monochromatic coherent signals. The ASAF analysis is inherently independent of models describing any spectral or spatial distribution of power. We demonstrate that the ASAF results can be appropriately combined over frequencies and sky directions to successfully recover the broadband directional and isotropic results