4 research outputs found
A randomized controlled trial of sucrose and/or pacifier as analgesia for infants receiving venipuncture in a pediatric emergency department
- Author
- AL Pereira
- B Stevens
- Ben Vandermeer
- EC Reis
- EM Blass
- EM Blass
- Hsing Jou
- J Bartfield
- KD Allen
- KJS Anand
- KJS Anand
- LA Ramenghi
- LA Ramenghi
- LS Franck
- M Eriksson
- M Gradin
- M Thyr
- MH Willis
- P Bossart
- PJ Lewindon
- RG Barr
- S MacLean
- Samina Ali
- Sarah J Curtis
- SI Merkel
- Stevens Bonnie
- T Voepel-Lewis
- Terry Klassen
- The American Academy of Pediatrics and the American Pain Society
- Publication venue
- BioMed Central
- Publication date
- 01/07/2007
- Field of study
<p>Abstract</p> <p>Background</p> <p>Although sucrose has been accepted as an effective analgesic agent for procedural pain in neonates, previous studies are largely in the NICU population using the procedure of heel lance. This is the first report of the effect of sucrose, pacifier or the combination thereof for the procedural pain of venipuncture in infants in the pediatric emergency department population.</p> <p>Methods</p> <p>The study design was a double (sucrose) and single blind (pacifier), placebo-controlled randomized trial – factorial design carried out in a pediatric emergency department. The study population was infants, aged 0 – 6 months. Eighty-four patients were randomly assigned to one of four groups: a) sucrose b) sucrose & pacifier c) control d) control & pacifier. Each child received 2 ml of either 44% sucrose or sterile water, by mouth. The primary outcome measure: FLACC pain scale score change from baseline. Secondary outcome measures: crying time and heart rate change from baseline.</p> <p>Results</p> <p>Sucrose did not significantly reduce the FLACC score, crying time or heart rate. However sub-group analysis revealed that sucrose had a much greater effect in the younger groups. Pacifier use reduced FLACC score (not statistically significant), crying times (statistically significant) but not heart rate. Subgroup analysis revealed a mean crying time difference of 76.52 seconds (p < 0.0171) (0–1 month) and 123.9 seconds (p < 0.0029) (1–3 month). For subgroup age > 3 months pacifier did not have any significant effect on crying time. Age adjusted regression analysis revealed that both sucrose and pacifier had significant effects on crying time. Crying time increased with both increasing age and increasing gestational age.</p> <p>Conclusion</p> <p>Pacifiers are inexpensive, effective analgesics and are easy to use in the PED for venipuncture in infants aged 0–3 months. The benefits of sucrose alone as an analgesic require further investigation in the older infant, but sucrose does appear to provide additional benefit when used with a pacifier in this age group.</p> <p>Trial registration</p> <p>Current Controlled Trials ISRCTN15819627</p
Japanese clinical guidelines for chronic pain in children and adolescents
- Author
- American Academy of Pediatrics Subcommittee on Chronic Abdominal Pain
- Anand
- Anand
- Apley
- Bakoula
- Balottin
- Berger
- Burke
- Bursch
- Campo
- Committee on Psychosocial Aspects of Child and Family Health
- Duhn
- Fature
- Flank
- Fumal
- Goodman
- Halac
- Helgeland
- Huguet
- Imbe
- International Association for the Study of Pain
- International Association for the Study of Pain
- International Headache Society
- Ishizaki
- Ishizaki
- Julius
- Lewandowski
- Lewis
- Loizzo
- Lynch
- Marazziti
- McGrath
- McGrath
- Merskey
- Patel
- Pawar
- Perquin
- Petersen
- Rasquin
- Saps
- Schils-Gibbons
- See
- Task Force of Clinical Practice Guidelines for Chronic Pain in Children and Adolescents of the Japanese Society of Psychosomatic Pediatrics
- Task Force on Taxonomy
- Traue
- van Dijk
- Weydert
- Wong
- Youssef
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Attitudes to End-of-Life Decisions in Paediatric Intensive Care
- Author
- Akdeniz Ăśniversitesi yogun bakim hemsireligi sertifika programi.
- Akpinar A.
- American Academy of Pediatrics Committee on Bioethics.
- American Nurses Association.
- American Nurses Association.
- American Society of Pain Management Nursing.
- Aslihan Akpinar
- Beauchamp TL
- Beckstrand RL
- California Coalition for Compassionate Care.
- Canadian Association of Critical Care Nurses.
- Committee on Bioethics American Academy of Pediatrics.
- Ersoy N.
- Jonsen AR
- Koc Universitesi yogun bakim hemsireligi sertifika programi.
- Körolu TF
- Muesser Ozcan Senses
- National Association of Neonatal Nurses.
- Rahime Aydin Er
- Romesberg TL
- Royal College of Paediatrics and Child Health.
- Stanley JM
- Task Force on the Nurse's Role in End-of-Life Decisions. Center for Ethics and Human Rights.
- Turkiye Cumhuriyeti (TC) Saglik Bakanligi 1. (Turkish Ministry of Health.)
- Turkiye Cumhuriyeti (TC) Saglik Bakanligi 1. (Turkish Ministry of Health.)
- Turkiye Cumhuriyeti (TC) Saglik Bakanligi. (Turkish Ministry of Health.)
- Turkiye Cumhuriyeti (TC) Saglik Bakanligi. (Turkish Ministry of Health.)
- Turkiye Cumhuriyeti (TC). Saglik Bakanligi 1. (Turkish Ministry of Health.)
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Drug monographs
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- Aaby
- AAP
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- Abdel-Latif
- Abdulla
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