260 research outputs found
Measurement of the branching fraction and CP content for the decay B(0) -> D(*+)D(*-)
- Author
- Abe K
- Abrams GS
- Adam I
- Adye T
- Albert J
- Aleksan R
- Allison J
- Alsmiller JRG
- Angelini C
- Anjomshoaa A
- Anulli F
- Arisaka K
- Aspinwall ML
- Aston D
- Aubert B
- BABAR Collaboration
- Back JJ
- Bagnasco S
- Baldini-Ferroli R
- Band HR
- Barillari T
- Barlow NR
- Barlow RJ
- Bartoldus R
- Batignani G
- Bauer JM
- Bellodi G
- Benayoun M
- Berger N
- Beringer J
- Bernard D
- Bernet R
- Best D
- Bettarini S
- Bevan AJ
- Bhimji W
- Bianchi F
- Bionta RM
- Blaylock G
- Blinov VE
- Bloom P
- Blouw J
- Bona M
- Bondioli M
- Bonneaud GR
- Borean C
- Borgland AW
- Bosisio L
- Boutigny D
- Bowerman DA
- Boyarski AM
- Boyd JT
- Bozzi C
- Brandt T
- Brau B
- Brau J
- Breon AB
- Briand H
- Brigljevic V
- Brochard F
- Brose J
- Brown CM
- Brown D
- Brown DN
- Bucci F
- Buchanan C
- Bugg W
- Bukin AD
- Bukin DA
- Burchat PR
- Button-Shafer J
- Buzykaev AR
- Buzzo A
- Cahn RN
- Calcaterra A
- Calderini G
- Campagna E
- Campagnari C
- Carpinelli M
- Cartaro C
- Cavallo N
- Cavoto G
- Chao M
- Charles E
- Chauveau J
- Chen E
- Chen GP
- Chen JC
- Cheng CH
- Chevalier N
- Christ S
- Chun S
- Clark PJ
- Cochran J
- Cohen-Tanugi J
- Cohn H
- Colberg T
- Colecchia F
- Contri R
- Convery MR
- Cottingham WN
- Coupal DP
- Cowan G
- Cowan R
- Crawley HB
- Cremaldi L
- Crosetti G
- Dahmes B
- Dal Corso F
- Dallapiccola C
- Dasu S
- Datta M
- Dauncey PD
- David P
- Davis CL
- De Groot N
- De Nardo G
- de Sangro R
- de Vaissiere C
- Del Buono L
- del Re D
- Della Ricca G
- Deppermann T
- Devmal S
- Di Lodovico F
- Dickopp M
- Dittongo S
- Dixon P
- Dong D
- Dorfan J
- Dorigo A
- Dubitzky RS
- Dubois-Felsmann GP
- Dunwoodie W
- Dvoretskii A
- Egede U
- Eichenbaum AM
- Eigen G
- Eisner AM
- Emery S
- Eschenburg V
- Eschrich I
- Fabozzi F
- Faccini R
- Falbo M
- Falciai D
- Farbin A
- Ferrag S
- Ferrarotto F
- Ferroni F
- Field RC
- Finocchiaro G
- Fischer PA
- Flood K
- Ford WT
- Forti AC
- Forti F
- Foster B
- Franek B
- Frank ED
- Frey R
- Fry JR
- Gabathuler E
- Gabriel TA
- Gaidot A
- Gaillard JM
- Galeazzi F
- Gamba D
- Gamet R
- Ganzhur SF
- Gatto C
- Geddes NI
- George M
- George S
- Gill MS
- Giorgi MA
- Giraud PF
- Gladney L
- Glanzman T
- Goetzen K
- Golubev VB
- Gopal GP
- Gowdy S
- Grauges E
- Green MG
- Gritsan AV
- Grosdidier G
- Grothe M
- Groysman Y
- Guo QH
- Haas T
- Haire M
- Halyo V
- Hamilton R
- Hamon O
- Harrison PF
- Harrison TJ
- Hart PA
- Harton JL
- Hast C
- Hauke A
- Hawkes CM
- Hearty C
- Henderson R
- Hertzbach SS
- Heusch CA
- Hicheur A
- Himel T
- Hitlin DG
- Hocker A
- Hryn'ova T
- Hu H
- Huffer ME
- Innes WR
- Ivanchenko VN
- Iwasaki M
- Izen JM
- Jackson F
- Jackson PD
- Jacobsen RG
- Jawahery A
- Jayatilleke S
- Jessop C
- Johnson JR
- Jolly S
- Judd D
- Kadel RW
- Kadyk J
- Karyotakis Y
- Kay M
- Kelsey MH
- Kerth LT
- Khan A
- Kim P
- Kirkby D
- Kitayama I
- Knowles DJ
- Koch H
- Kocian ML
- Kofler R
- Kolomensky YG
- Koptchev VB
- Kordich TMB
- Korol AA
- Kowalewski R
- Kozanecki W
- Kral JF
- Kravchenko EA
- Krishnamurthy M
- Kroeger R
- Kunze M
- Kurup A
- Kuznetsova N
- Lacker HM
- Lafferty GD
- Lamsa J
- Lanceri L
- Lange D
- Langenegger U
- Langer M
- Lankford AJ
- Laplace S
- Lavin D
- Le Diberder F
- LeClerc C
- Lees JP
- Leith DWGS
- Lepeltier V
- Leruste P
- Levi ME
- Levy SL
- Lewandowski B
- Lillard V
- Lista L
- Liu R
- Lo Vetere M
- Lockman WS
- London GW
- Long O
- LoSecco JM
- Lou XC
- Lu A
- Lu C
- Luitz S
- Lusiani A
- Luth V
- Lutz AM
- Lynch G
- Lynch HL
- MacFarlane DB
- Mackay C
- Macri M
- Mallik U
- Maly E
- Mancinelli G
- Mandelkern M
- Manfredi PF
- Marchiori G
- Margoni M
- Marker CE
- Marsiske H
- Martinez-Vidal F
- Mattison TS
- Mayer B
- Mazur MA
- Mazzoni MA
- McKemey AK
- McKenna JA
- McMahon S
- McMahon TR
- Meadows BT
- Menke S
- Messner R
- Metzler S
- Meyer TI
- Meyer WT
- Michelon G
- Miftakov V
- Milek M
- Monchenault GH
- Monge MR
- Moore TB
- Morandin M
- Morganti M
- Morganti S
- Morii M
- Morton GW
- Mugge M
- Muheim F
- Muller DR
- Muller-Pfefferkorn R
- Nash JA
- Nauenberg U
- Neal H
- Neri N
- Nicholson H
- Nief JY
- O'Grady CP
- O'Neale SW
- Ocariz J
- Oddone PJ
- Olivas A
- Olsen J
- Onuchin AP
- Otto S
- Oyang J
- Ozcan VE
- Paick K
- Palano A
- Palombo F
- Pan Y
- Panetta J
- Panvini RS
- Paoloni E
- Paolucci P
- Passaggio S
- Pastore FC
- Patel PM
- Patrignani C
- Patteri P
- Payne DJ
- Penny RC
- Perazzo A
- Perl M
- Peruzzi IM
- Peters K
- Petrak S
- Piccolo D
- Piccolo M
- Piemontese L
- Piredda G
- Pivk M
- Plaszczynski S
- Playfer S
- Pompili A
- Poropat P
- Porter FC
- Posocco M
- Potter RJL
- Prell S
- Prepost R
- Pripstein M
- Pulliam T
- Purohit MV
- Qi ND
- Quinn H
- Rahatlou S
- Rama M
- Rankin P
- Ratcliff BN
- Raven G
- Re V
- Reidy J
- Ricciardi S
- Richman JD
- Rizzo G
- Roat C
- Robbe P
- Roberts DA
- Robertson SH
- Robutti E
- Roe NA
- Romosan A
- Ronan MT
- Roney JM
- Rong G
- Roodman A
- Roos L
- Rosenberg EI
- Rotondo M
- Roy J
- Ryd A
- Salnikov AA
- Salvatore F
- Samuel A
- Sanders DA
- Sanders P
- Sandrelli F
- Santroni A
- Savvas N
- Schaffner SF
- Schalk T
- Schieck JR
- Schietinger T
- Schindler RH
- Schmitz RE
- Schmuecker H
- Schubert KR
- Schumm BA
- Schune MH
- Schwiening J
- Schwierz R
- Sciacca C
- Sciolla G
- Scott IJ
- Seiden A
- Sekula SJ
- Serednyakov SI
- Serfass B
- Serra M
- Sharma V
- Shelkov VG
- Shorthouse HW
- Simi G
- Simonetto F
- Sinev NB
- Singh H
- Skovpen YI
- Sloane RJ
- Smith AJS
- Smith D
- Smith JG
- Snyder A
- Soffer A
- Soha A
- Sokoloff MD
- Spaan B
- Spanier SM
- Speziali V
- Staengle H
- Stark J
- Steinke M
- Stelzer J
- Stoker DP
- Stroili R
- Strom D
- Strother P
- Stugu B
- Su D
- Sullivan MK
- Summers DJ
- Swain JE
- T'Jampens S
- Tanaka HA
- Taras P
- Taylor F
- Telnov AV
- Telnov VI
- Thiebaux C
- Thiessen D
- Tinslay J
- Tisserand V
- Toki WH
- Torassa E
- Tosi S
- Touramanis C
- Treadwell E
- Triggiani G
- Trincaz-Duvoid S
- Tumanov A
- Turnbull L
- Turri M
- Va'vra J
- Vaitsas G
- van Bibber K
- van Hoek WC
- Varnes EW
- Vasileiadis G
- Vasseur G
- Verderi M
- Verkerke W
- Vidal PB
- Voci C
- Voena C
- von Wimmersperg-Toeller JH
- Vuagnin G
- Wagner SR
- Wagoner DE
- Waldi R
- Walkowiak W
- Walsh J
- Wang P
- Watson AT
- Watson NK
- Weatherall JH
- Weaver M
- Weidemann AW
- Weinstein AJR
- Wenzel WA
- Wilden L
- Williams DC
- Williams JC
- Willocq S
- Wilson FF
- Wilson MG
- Wilson RJ
- Wisniewski WJ
- Wormser G
- Wright DH
- Wright DM
- Wu SL
- Xella SM
- Xie Y
- Yamamoto RK
- Yang S
- Yeche C
- Yi J
- Young CC
- Yu Z
- Yumiceva FX
- Yushkov AN
- Zallo A
- Zghiche A
- Zhang J
- Zhang L
- Zhu RY
- Zhu YS
- Zito M
- Publication venue
- American Physical Society
- Publication date
- 01/01/2002
- Field of study
This is the pre-print version of the Article. The official published version can be accessed from the links below. Copyright @ 2002 APS.We report a measurement of the branching fraction of the decay B0âD*+D*- and of the CP-odd component of its final state using the BABAR detector. With data corresponding to an integrated luminosity of 20.4ââfb-1 collected at the ΄(4S) resonance during 1999â2000, we have reconstructed 38 candidate signal events in the mode B0âD*+D*- with an estimated background of 6.2±0.5 events. From these events, we determine the branching fraction to be B(B0âD*+D*-)=[8.3±1.6(stat)±1.2(syst)]Ă10-4. The measured CP-odd fraction of the final state is 0.22±0.18(stat)±0.03(syst).This work is supported by DOE and NSF (USA), NSERC (Canada), IHEP (China), CEA and CNRS-IN2P3 (France), BMBF (Germany), INFN (Italy), NFR (Norway), MIST (Russia), and PPARC (United Kingdom). Individuals have received support from the A.P. Sloan Foundation, Research Corporation, and Alexander von Humboldt Foundation
Measurement of D-s(+) and D-s(*+) production in B meson decays and from continuum e(+)e(-) annihilation at âs=10.6 GeV
- Author
- Abe K
- Abrams GS
- Adam I
- Adye T
- Albert J
- Aleksan R
- Allison J
- Alsmiller JRG
- Andress JC
- Angelini C
- Anjomshoaa A
- Anthony PL
- Anulli F
- Arisaka K
- Aspinwall ML
- Aston D
- Aubert B
- Azzopardi DE
- BABAR Collaboration
- Back JJ
- Bagnasco S
- Baird K
- Baldini-Ferroli R
- Band HR
- Barillari T
- Barlow NR
- Barlow RJ
- Bartoldus R
- Batignani G
- Bauer JM
- Benayoun M
- Berger N
- Beringer J
- Bernard D
- Bernet R
- Best D
- Bettarini S
- Bhimji W
- Bianchi F
- Bionta RM
- Blaylock G
- Blinov VE
- Bloom E
- Bloom P
- Blouw J
- Bona M
- Bondioli M
- Bonneaud GR
- Borean C
- Borgland AW
- Bosisio L
- Boutigny D
- Bowerman DA
- Boyarski AM
- Boyd JT
- Bozzi C
- Brandt T
- Brau B
- Brau J
- Breon AB
- Briand H
- Bright-Thomas PG
- Brigljevic V
- Brochard F
- Brose J
- Brown CM
- Brown D
- Brown DN
- Buchanan C
- Bugg W
- Bukin AD
- Bukin DA
- Bulos F
- Burchat PR
- Button-Shafer J
- Buzykaev AR
- Buzzo A
- Cahn RN
- Calcaterra A
- Calderini G
- Campagnari C
- Carpinelli M
- Carroll M
- Cartaro C
- Cavallo N
- Cavoto G
- Chao M
- Charles E
- Chauveau J
- Chen E
- Chen GP
- Chen JC
- Cheng CH
- Chevalier N
- Christ S
- Chun S
- Clark AR
- Clark PJ
- Cochran J
- Cohen-Tanugi J
- Cohn H
- Colberg T
- Colecchia F
- Contri R
- Convery MR
- Copty N
- Cottingham WN
- Coupal DP
- Cowan G
- Cowan R
- Coward DH
- Crawley HB
- Cremaldi L
- Crosetti G
- Dahmes B
- Dal Corso F
- Dallapiccola C
- Dasu S
- Dauncey PD
- David P
- Davis CL
- De Groot N
- de la Vaissiere C
- de Lesquen A
- de Monchenault GH
- De Nardo G
- de Sangro R
- Del Buono L
- del Re D
- Della Ricca G
- Deppermann T
- Devmal S
- Di Lodovico F
- Dickopp M
- Dima MO
- Dittongo S
- Dixon P
- Dorfan DE
- Dorfan J
- Dorigo A
- Dubitzky RS
- Dubois-Felsmann GP
- Dunwoodie W
- Dvoretskii A
- Dyce N
- Egede U
- Eichenbaum AM
- Eigen G
- Eisner AM
- Elmer P
- Emery S
- Eschenburg V
- Eschrich I
- Fabozzi F
- Faccini R
- Fahey S
- Falbo M
- Falciai D
- Farbin A
- Ferrag S
- Ferrarotto F
- Ferroni F
- Field RC
- Finocchiaro G
- Fischer PA
- Flood K
- Ford WT
- Forti AC
- Forti F
- Foster B
- Franek B
- Frank ED
- Frey R
- Fry JR
- Fullwood J
- Gabathuler E
- Gabriel TA
- Gaidot A
- Gaillard JM
- Galeazzi F
- Gamba D
- Gamet R
- Ganzhur SF
- Gatto C
- Geddes NI
- Geld TL
- George M
- George S
- Gill MS
- Giorgi MA
- Giraud PF
- Gladney L
- Glanzman T
- Godfrey GL
- Goetzen K
- Golubev VB
- Gopal GP
- Gowdy S
- Green MG
- Grillo AA
- Gritsan AV
- Grosdidier G
- Grosso P
- Grothe M
- Groysman Y
- Gunawardane NJW
- Guo QH
- Haas T
- Haire M
- Hamilton R
- Hamon O
- Handler T
- Harrison PF
- Harrison TJ
- Hart PA
- Harton JL
- Hast C
- Hauke A
- Hawkes CM
- Hearty C
- Henderson R
- Hertzbach SS
- Heusch CA
- Hicheur A
- Himel T
- Hitlin DG
- Hocker A
- Hryn'ova T
- Hu H
- Huffer ME
- Innes WR
- Ivanchenko VN
- Iwasaki M
- Izen JM
- Jackson F
- Jackson PD
- Jacobsen RG
- Jawahery A
- Jayatilleke S
- Jessop C
- Johnson DR
- Johnson JR
- Johnson RP
- Jolly S
- Judd D
- Kadel RW
- Kadyk J
- Karyotakis Y
- Kay M
- Kelsey MH
- Kerth LT
- Khan A
- Kim P
- Kirkby D
- Kitayama I
- Knowles DJ
- Koch H
- Kocian ML
- Kofler R
- Kolomensky YG
- Koptchev VG
- Kordich TMB
- Korol AA
- Kowalewski R
- Kozanecki W
- Kral JF
- Kravchenko EA
- Krishnamurthy M
- Kroeger R
- Kunze M
- Kurup A
- Kuznetsova N
- Lacker HM
- Lafferty GD
- Lamanna E
- Lamsa J
- Lanceri L
- Lange D
- Langenegger U
- Langer M
- Lankford AJ
- Laplace S
- Lavin D
- Le Diberder F
- LeClerc C
- Lees JP
- Leith DWGS
- Leonardi E
- Lepeltier V
- Leruste P
- Levi ME
- Levy SL
- Lewandowski B
- Lillard V
- Lista L
- Liu R
- Lo Vetere M
- Lockman WS
- London GW
- Long O
- LoSecco JM
- Lou XC
- Lu A
- Lu C
- Luitz S
- Lusiani A
- Luth V
- Lutz AM
- Lynch G
- Lynch HL
- MacFarlane DB
- Mackay C
- Macri M
- Mallik U
- Maly E
- Mancinelli G
- Mandelkern M
- Manfredi PF
- Margoni M
- Marker CE
- Marsiske H
- Martin JP
- Martinez-Vidal F
- Mattison TS
- Mayer B
- Mazzoni MA
- McDonald KT
- McGrath P
- McKemey AK
- McKenna JA
- McMahon S
- McMahon TR
- Meadows BT
- Menke S
- Messner R
- Metzler S
- Meyer TI
- Meyer WT
- Michelon G
- Miftakov V
- Milek M
- Moffeit KC
- Monge MR
- Moore TB
- Morandin M
- Morganti M
- Morganti S
- Morii M
- Mount R
- Mugge M
- Muheim F
- Muller DR
- Muller-Pfefferkorn R
- Nash JA
- Nauenberg U
- Neal H
- Neri N
- Nicholson H
- Nief JY
- O'Grady CP
- O'Neale SW
- Ocariz J
- Oddone PJ
- Olivas A
- Olsen J
- Onuchin AP
- Otto S
- Oyang J
- Ozcan VE
- Paick K
- Palano A
- Palombo F
- Pan Y
- Panetta J
- Panvini RS
- Paoloni E
- Paolucci P
- Passaggio S
- Pastore FC
- Patel PM
- Patrignani C
- Patteri P
- Payne DJ
- Penny RC
- Perazzo A
- Perl M
- Peruzzi IM
- Peters K
- Petrak S
- Pia MG
- Piccolo D
- Piccolo M
- Piemontese L
- Piredda G
- Plaszczynski S
- Playfer S
- Pompili A
- Poropat P
- Porter FC
- Posocco M
- Potter RJL
- Prell S
- Prepost R
- Pripstein M
- Pulliam T
- Purohit MV
- Qi ND
- Quinn H
- Rahatlou S
- Rama M
- Rankin P
- Ratcliff BN
- Raven G
- Re V
- Reidy J
- Ricciardi S
- Richman JD
- Rizzo G
- Roat C
- Robbe P
- Roberts DA
- Robertson SH
- Robutti E
- Rochester LS
- Roe NA
- Romosan A
- Ronan MT
- Roney JM
- Rong G
- Roodman A
- Roos L
- Rosenberg EI
- Rotondo M
- Roussot E
- Roy J
- Ryd A
- Sadrozinski H
- Salnikov AA
- Salvatore F
- Samuel A
- Sanders DA
- Sanders P
- Sandrelli F
- Santroni A
- Savvas N
- Schaffner SF
- Schalk T
- Schieck JR
- Schietinger T
- Schindler RH
- Schmitz RE
- Schmuecker H
- Schubert KR
- Schumm BA
- Schune MH
- Schwiening J
- Schwierz R
- Sciacca C
- Sciolla G
- Scott I
- Scott IJ
- Seiden A
- Seitz R
- Sekula SJ
- Sen S
- Serbo VV
- Serednyakov SI
- Serfass B
- Serra M
- Sharma V
- Shelkov VG
- Shorthouse HW
- Simi G
- Simonetto F
- Simopoulos ET
- Sinev NB
- Singh H
- Skovpen YI
- Sloane RJ
- Smith AJS
- Smith D
- Smith JG
- Smol A
- Snyder A
- Soffer A
- Soha A
- Sokoloff MD
- Spaan B
- Spanier SM
- Speziali V
- Staengle H
- Stark J
- Steinke M
- Stelzer J
- Stoker DP
- Stroili R
- Strom D
- Strother P
- Stugu B
- Su D
- Sullivan MK
- Summers DJ
- Sutton CS
- Swain JE
- T'Jampens S
- Tanaka HA
- Taras P
- Taylor F
- Tehrani FS
- Telnov AV
- Telnov VI
- Thiebaux C
- Thiessen D
- Tinslay J
- Tisserand V
- Toki WH
- Torassa E
- Tosi S
- Touramanis C
- Treadwell E
- Triggiani G
- Trincaz-Duvoid S
- Tumanov A
- Turnbull L
- Turri M
- Va'vra J
- Vaitsas G
- van Bibber K
- van Hoek WC
- Varnes EW
- Vasileiadis G
- Vasseur G
- Verderi M
- Verkerke W
- Versille S
- Vidal PB
- Voci C
- Voena C
- von Wimmersperg-Toeller JH
- Vuagnin G
- Wagner DL
- Wagner SR
- Wagoner DE
- Waldi R
- Walkowiak W
- Wallom D
- Walsh J
- Wang P
- Watson AT
- Watson NK
- Weatherall JH
- Weaver M
- Weidemann AW
- Weinstein AJR
- Wenzel WA
- Wilden L
- Williams DC
- Williams MI
- Willocq S
- Wilson FF
- Wilson MG
- Wilson RJ
- Wisniewski WJ
- Witherell M
- Wormser G
- Wright DH
- Wright DM
- Wu SL
- Xella SM
- Xie Y
- Yamamoto RK
- Yang S
- Yeche C
- Yellin S
- Young CC
- Yu Z
- Yumiceva FX
- Yushkov AN
- Zacek V
- Zallo A
- Zhang J
- Zhu RY
- Zhu YS
- Zito M
- Publication venue
- American Physical Society
- Publication date
- 01/01/2002
- Field of study
This is the pre-print version of the Article. The official published version can be accessed from the links below. Copyright @ 2002 APSNew measurements of Ds+ and Ds*+ meson production rates from B decays and from qqÌ
continuum events near the ΄(4S) resonance are presented. Using 20.8 fb-1 of data on the ΄(4S) resonance and 2.6 fb-1 off-resonance, we find the inclusive branching fractions B(BâDs+X)=(10.93±0.19±0.58±2.73)% and B(BâDs*+X)=(7.9±0.8±0.7±2.0)%, where the first error is statistical, the second is systematic, and the third is due to the Ds+âÏÏ+ branching fraction uncertainty. The production cross sections Ï(e+e-âDs+X)ĂB(Ds+âÏÏ+)=7.55±0.20±0.34pb and Ï(e+e-âDs*±X)ĂB(Ds+âÏÏ+)=5.8±0.7±0.5pb are measured at center-of-mass energies about 40 MeV below the ΄(4S) mass. The branching fractions ÎŁB(BâDs(*)+D(*))=(5.07±0.14±0.30±1.27)% and ÎŁB(BâDs*+D(*))=(4.1±0.2±0.4±1.0)% are determined from the Ds(*)+ momentum spectra. The mass difference m(Ds+)-m(D+)=98.4±0.1±0.3MeV/c2 is also measured.This work was supported by DOE and NSF (USA), NSERC (Canada), IHEP (China), CEA and CNRS-IN2P3 (France), BMBF (Germany), INFN (Italy), NFR (Norway), MIST (Russia), and PPARC (United Kingdom). Individuals have received support from the Swiss NSF, A. P. Sloan Foundation, Research Corporation, and Alexander von Humboldt Foundation
Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- Author
- A Abbate
- A Abhyankar
- A Adams
- A Agafina
- A Akyea-Djamson
- A Alan
- A Alfieri
- A Alfrey
- A Alvarisqueta
- A Amos
- A Anadiotis
- A Anneveldt
- A Antolick
- A Arthur
- A Aslam
- Abaci F
- Abdullakutty J
- Abhaichand R
- Abib E Jr
- Aboufakher R
- Abrantes J
- Abreu M
- Abulencia K
- Acampora D
- Acampora M
- Accini Mendoza Jl
- Aceto L
- Acevedo B
- Acevedo L
- Acheatel R
- Actis Mv
- Adams M
- Adjic Nc
- Affaki Gs
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- Aggarwal Rk
- Agosta Gf
- Aguilar M
- Aguilar M
- Ahire N
- Ahmad I
- Ahmed Sh
- Ahn Y
- Aish B
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- Aiub J
- Ajax K
- Ajioka M
- Akai Y
- Akatova E
- Akrap B
- Al Joundi T
- Al-Khalili F
- Albisu J
- Alcalde Jm
- Alcide P
- Alfonso T
- Allen J
- Alllison Dc
- Almaliky T
- Amerena J
- Andersen K
- Andor M
- Angelova I
- Angiolillo D
- Anita S
- Anker Sd
- Antalik L
- Antonicelli R
- Aparicio Cv
- Apel T
- Apostolovic S
- Ara M
- Aragorn L
- Arango Jl
- Araujo Fonseca M
- Ardissino D
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- Arevalo S
- Argiolas G
- Arif I
- Armas E
- Aron G
- Arora S
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- Ashcom T
- Ashford M
- Ashino K
- Asim Oktay Ao
- Assarsson E
- Ata B
- Ather N
- Atieh M
- Aull L
- Avalos V
- Avdonina N
- Awasthi Ak
- Axthelm C
- Ayala M
- Ayasse D
- Ayasse M
- Azizad M
- Azize Gm
- B Becker
- Baar M
- Babu R
- Backer T
- Badea C
- Baden M
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- Baek C
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- Bailey K
- Bailey S
- Bair S
- Baker A
- Baker C
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- Bakker H
- Baksi A
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- Ballantyne C
- Ballmajo M
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- Banker K
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- Barroso W
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- Bartuseviciene S
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- Belohlavek J
- Bendelow T
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- Benedetti G
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- Bergeron P
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- Blazsek Z
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- Bluemel J
- Blumberg C
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- Brodmann M
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- Cheung D
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- Christensen L
- Christenson S
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- Clocotan M
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- Hutchens E
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- I Ilic
- I Ivanov
- Iachini K
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- Ibarra J
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- Ichisawa M
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- Infusino F
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- Iteld B
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- J Jiang
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- Jaguszewska G
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- M Malek
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- Zieve F
- Zineldine A.
- Zirlik A
- Zucchetti C
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2017
- Field of study
Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1ÎČ, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1ÎČ innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.
Lawson criterion for ignition exceeded in an inertial fusion experiment
- Author
- Abu-Shawareb H
- Acree R
- Adams J
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- Addis B
- Aden R
- Adrian P
- Afeyan BB
- Aggleton M
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- Aguirre A
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- Albright BJ
- Albritton J
- Alcala J
- Alday C
- Alessi DA
- Alexander N
- Alfonso J
- Alfonso N
- Alger E
- Ali SJ
- Ali ZA
- Alley WE
- Amala P
- Amendt PA
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- Ammula S
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- Ampleford DJ
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- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 06/07/2022
- Field of study
For more than half a century, researchers around the world have been engaged in attempts to achieve fusion ignition as a proof of principle of various fusion concepts. Following the Lawson criterion, an ignited plasma is one where the fusion heating power is high enough to overcome all the physical processes that cool the fusion plasma, creating a positive thermodynamic feedback loop with rapidly increasing temperature. In inertially confined fusion, ignition is a state where the fusion plasma can begin "burn propagation" into surrounding cold fuel, enabling the possibility of high energy gain. While "scientific breakeven" (i.e., unity target gain) has not yet been achieved (here target gain is 0.72, 1.37Â MJ of fusion for 1.92Â MJ of laser energy), this Letter reports the first controlled fusion experiment, using laser indirect drive, on the National Ignition Facility to produce capsule gain (here 5.8) and reach ignition by nine different formulations of the Lawson criterion
Measurement of the Ratio of b Quark Production Cross Sections in Antiproton-Proton Collisions at 630 GeV and 1800 GeV
- Author
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- Zucchelli Stison TS
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2002
- Field of study
We report a measurement of the ratio of the bottom quark production cross
section in antiproton-proton collisions at 630 GeV to 1800 GeV using bottom
quarks with transverse momenta greater than 10.75 GeV identified through their
semileptonic decays and long lifetimes. The measured ratio
sigma(630)/sigma(1800) = 0.171 +/- .024 +/- .012 is in good agreement with
next-to-leading order (NLO) quantum chromodynamics (QCD)
Pan-cancer analysis of whole genomes
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- The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium View Correspondence (jump link)
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- ya Al-Ahmadie
- Yachida
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- z ah
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- zd Gershenwald
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- zf Ghossein
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang H. b
- Zhao
- Zheng
- Zhou
- Zhou
- Zhu
- Zhu
- zi zj
- zm Jayaseelan
- Zou
- Zou
- zt Kim
- zw Lewis
- Ă. A. th
- Ă. sk
- Publication venue
- Publication date
- 11/12/2019
- Field of study
Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale(1-3). Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4-5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter(4); identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation(5,6); analyses timings and patterns of tumour evolution(7); describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity(8,9); and evaluates a range of more-specialized features of cancer genomes(8,10-18).Peer reviewe
Measurement of the inclusive and differential Higgs boson production cross sections in the decay mode to a pair of Ï Leptons in pp collisions at sqrt[s]=13ââTeV
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- Yohay R
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- Yoo J
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- Yumiceva F
- Yusli MN
- Zabi A
- Zacharopoulou A
- Zahid S
- Zaleski S
- Zalewski P
- Zanetti M
- Zarubin A
- Zarucki M
- Zecchinelli AG
- Zeinali M
- Zeuner WD
- Zghiche A
- Zhang F
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- Zhang Y
- Zhang Z
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- Zhizhin I
- Zhokin A
- Zhu DH
- Zhu RY
- Ziemons T
- Zoi I
- Zolkapli Z
- Zorbakir IS
- Zorbilmez C
- Zotto P
- Zotz A
- Zou D
- Zou R
- Zucchetta A
- Zumerle G
- Zuo X
- Zuolo D
- Zygala L
- Ălvarez FernĂĄndez A
- Ăzçelik Ă
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2022
- Field of study
Measurements of the inclusive and differential fiducial cross sections of the Higgs boson are presented, using the Ï lepton decay channel. The differential cross sections are measured as functions of the Higgs boson transverse momentum, jet multiplicity, and transverse momentum of the leading jet in the event, if any. The analysis is performed using proton-proton collision data collected with the CMS detector at the LHC at a center-of-mass energy of 13ââTeV and corresponding to an integrated luminosity of 138ââfb^{-1}. These are the first differential measurements of the Higgs boson cross section in the final state of two Ï leptons. In final states with a large jet multiplicity or with a Lorentz-boosted Higgs boson, these measurements constitute a significant improvement over measurements performed in other final states
Observation of a New Excited Beauty Strange Baryon Decaying to Îb- Ï+Ï-
- Author
- Aarrestad TK
- Aarup Petersen H
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abercrombie D
- Abu Zeid S
- Acharya H
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- Alcaraz Maestre J
- Aldaya Martin M
- AldĂĄ JĂșnior WL
- Aleksandrov A
- Alexander J
- Alhusseini M
- Alimena J
- Alison J
- Almond J
- Alvarez Gonzalez B
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- Zorbilmez C
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- Zou D
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- Ălvarez FernĂĄndez A
- Ăzçelik Ă
- Publication venue
- American Physical Society
- Publication date
- 01/01/2021
- Field of study
The Îb-Ï+Ï- invariant mass spectrum is investigated with an event sample of proton-proton collisions at s=13 TeV, collected by the CMS experiment at the LHC in 2016-2018 and corresponding to an integrated luminosity of 140 fb-1. The ground state Îb- is reconstructed via its decays to J/ÏÎ- and J/ÏÎK-. A narrow resonance, labeled Îb(6100)-, is observed at a Îb-Ï+Ï- invariant mass of 6100.3±0.2(stat)±0.1(syst)±0.6(Îb-) MeV, where the last uncertainty reflects the precision of the Îb- baryon mass. The upper limit on the Îb(6100)- natural width is determined to be 1.9 MeV at 95% confidence level. The low Îb(6100)- signal yield observed in data does not allow a measurement of the quantum numbers of the new state. However, following analogies with the established excited Îc baryon states, the new Îb(6100)- resonance and its decay sequence are consistent with the orbitally excited Îb- baryon, with spin and parity quantum numbers JP=3/2-
The impact of viral mutations on recognition by SARS-CoV-2 specific TÂ cells.
- Author
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- Abudahab K
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- Adeniji K
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- Publication venue
- iScience
- Publication date
- 01/01/2021
- Field of study
We identify amino acid variants within dominant SARS-CoV-2 TÂ cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of recognition by epitope-specific TÂ cells assessed by IFN-Îł and cytotoxic killing assays. Complete loss of TÂ cell responsiveness was seen due to Q213K in the Aâ01:01-restricted CD8+ ORF3a epitope FTSDYYQLY207-215; due to P13L, P13S, and P13T in the Bâ27:05-restricted CD8+ nucleocapsid epitope QRNAPRITF9-17; and due to T362I and P365S in the Aâ03:01/Aâ11:01-restricted CD8+ nucleocapsid epitope KTFPPTEPK361-369. CD8+ TÂ cell lines unable to recognize variant epitopes have diverse TÂ cell receptor repertoires. These data demonstrate the potential for TÂ cell evasion and highlight the need for ongoing surveillance for variants capable of escaping TÂ cell as well as humoral immunity.This work is supported by the UK Medical Research Council (MRC); Chinese Academy of Medical Sciences(CAMS) Innovation Fund for Medical Sciences (CIFMS), China; National Institute for Health Research (NIHR)Oxford Biomedical Research Centre, and UK Researchand Innovation (UKRI)/NIHR through the UK Coro-navirus Immunology Consortium (UK-CIC). Sequencing of SARS-CoV-2 samples and collation of data wasundertaken by the COG-UK CONSORTIUM. COG-UK is supported by funding from the Medical ResearchCouncil (MRC) part of UK Research & Innovation (UKRI),the National Institute of Health Research (NIHR),and Genome Research Limited, operating as the Wellcome Sanger Institute. T.I.d.S. is supported by a Well-come Trust Intermediate Clinical Fellowship (110058/Z/15/Z). L.T. is supported by the Wellcome Trust(grant number 205228/Z/16/Z) and by theUniversity of Liverpool Centre for Excellence in Infectious DiseaseResearch (CEIDR). S.D. is funded by an NIHR GlobalResearch Professorship (NIHR300791). L.T. and S.C.M.are also supported by the U.S. Food and Drug Administration Medical Countermeasures Initiative contract75F40120C00085 and the National Institute for Health Research Health Protection Research Unit (HPRU) inEmerging and Zoonotic Infections (NIHR200907) at University of Liverpool inpartnership with Public HealthEngland (PHE), in collaboration with Liverpool School of Tropical Medicine and the University of Oxford.L.T. is based at the University of Liverpool. M.D.P. is funded by the NIHR Sheffield Biomedical ResearchCentre (BRC â IS-BRC-1215-20017). ISARIC4C is supported by the MRC (grant no MC_PC_19059). J.C.K.is a Wellcome Investigator (WT204969/Z/16/Z) and supported by NIHR Oxford Biomedical Research Centreand CIFMS. The views expressed are those of the authors and not necessarily those of the NIHR or MRC
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- Yip CK
- Yiu SPT
- Yoo YH
- Yoshida K
- Yoshii SR
- Yoshimori T
- Yousefi B
- Yu B
- Yu H
- Yu J
- Yu J
- Yu L
- Yu M-L
- Yu S-W
- Yu VC
- Yu WH
- Yu Z
- Yu Z
- Yuan J
- Yuan L-Q
- Yuan S
- Yuan S-SF
- Yuan Y
- Yuan Z
- Yue J
- Yue Z
- Yun J
- Yung RL
- Zacks DN
- Zaffagnini G
- Zambelli VO
- Zanella I
- Zang QS
- Zanivan S
- Zappavigna S
- Zaragoza P
- Zarbalis KS
- Zarebkohan A
- Zarrouk A
- Zeitlin SO
- Zeng J
- Zeng J-D
- Zhan L
- Zhang B
- Zhang DD
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H-L
- Zhang J
- Zhang J
- Zhang J-P
- Zhang KYB
- Zhang L
- Zhang L
- Zhang L
- Zhang L
- Zhang LW
- Zhang M
- Zhang P
- Zhang S
- Zhang W
- Zhang X
- Zhang X
- Zhang X
- Zhang X
- Zhang X
- Zhang X-W
- Zhang XD
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y-D
- Zhang Y-Y
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhao H
- Zhao L
- Zhao S
- Zhao T
- Zhao X-F
- Zhao Y
- Zhao Y
- Zhao Y
- Zhao Y
- Zheng G
- Zheng K
- Zheng L
- Zheng S
- Zheng X-L
- Zheng Y
- Zheng Z-G
- Zhivotovsky B
- Zhong Q
- Zhou A
- Zhou B
- Zhou C
- Zhou G
- Zhou H
- Zhou H
- Zhou H
- Zhou J
- Zhou J
- Zhou J
- Zhou J
- Zhou K
- Zhou R
- Zhou X-J
- Zhou Y
- Zhou Y
- Zhou Y
- Zhou Z
- Zhou Z-Y
- Zhu B
- Zhu C
- Zhu G-Q
- Zhu H
- Zhu H
- Zhu H
- Zhu W-G
- Zhu Y
- Zhu Y
- Zhuang H
- Zhuang X
- Zientara-Rytter K
- Zimmermann CM
- Ziviani E
- Zoladek T
- Zong W-X
- Zorov DB
- Zorzano A
- Zou W
- Zou Z
- Zou Z
- Zuryn S
- Zwerschke W
- Ălvarez ĂMC
- Ăvalos Y
- Ănal G
- ĂstĂŒn S
- ÄoliÄ M
- ÄokiÄ J
- Ćœerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
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