Great Sexpectations: Analyzing the Influence of Expectation and Desire on Sexual Behaviors Performed in Hookups

Sexual acts performed in college hookups are determined by a variety of factors. A significant problem is that culturally driven taboos cloud open communication during hookups leading to unexpressed expectations. These unexpressed expectations play a large role in sexual decision-making. Ideally, hookup partners would only engage in acts they desire, but culturally driven expectations are powerful forces, and may lead to the performance of less-preferred acts. Norm driven expectations develop into persistent sexual scripts that young adults follow closely. Moreover, the influence of expectations may be gendered due to sex role traditionality. Implications for hookup behavior are discussed.https://orb.binghamton.edu/research_days_posters/1008/thumbnail.jp

The Friend zone: An In/inite Place Where Nothing Good Happens: A Comprehensive Study of Friend zoning Across Varying Genders and Sexual Orientations

“Friend zone” is a popular culture term used to describe a friendship where one member in a friend dyad desires a romantic or sexual relationship and the other member does not. Sexual Script Theory (Simon & Gagnon, 2003) and Sexual Strategies Theory (Buss & Schmidt, 1993) suggest that individuals will typically view the friend zone as a Qield dominated by female-to-male interactions, given sexual scripts on women as gatekeepers and men as being more active in initiating relationships. It may be expected then that men and women and individuals who are not exclusively heterosexual may then follow different scripts for making and negotiating friend zone choices. There is very little data available concerning instances of the use of the term friend zone in same-sex friendship interactions. Individuals are typically expected to have relationships that conform to the heteronormative script, so most people are resistant to the thought of being attracted to others of the same sex (Lamb, 2004). Because of this, many “best friendships” between those of the same sex have been used as protection against claims of same-sex attraction/relationships (Lamb, 2004). Given the lack of research on same-sex friend zoning, as well as the restrictive nature of heteronormative scripts, the current study explores the practice of friend zoning within same-sex friendships.https://orb.binghamton.edu/research_days_posters/1003/thumbnail.jp

Cardiac myosin activation with omecamtiv mecarbil in systolic heart failure

BACKGROUND The selective cardiac myosin activator omecamtiv mecarbil has been shown to improve cardiac function in patients with heart failure with a reduced ejection fraction. Its effect on cardiovascular outcomes is unknown. METHODS We randomly assigned 8256 patients (inpatients and outpatients) with symptomatic chronic heart failure and an ejection fraction of 35% or less to receive omecamtiv mecarbil (using pharmacokinetic-guided doses of 25 mg, 37.5 mg, or 50 mg twice daily) or placebo, in addition to standard heart-failure therapy. The primary outcome was a composite of a first heart-failure event (hospitalization or urgent visit for heart failure) or death from cardiovascular causes. RESULTS During a median of 21.8 months, a primary-outcome event occurred in 1523 of 4120 patients (37.0%) in the omecamtiv mecarbil group and in 1607 of 4112 patients (39.1%) in the placebo group (hazard ratio, 0.92; 95% confidence interval [CI], 0.86 to 0.99; P = 0.03). A total of 808 patients (19.6%) and 798 patients (19.4%), respectively, died from cardiovascular causes (hazard ratio, 1.01; 95% CI, 0.92 to 1.11). There was no significant difference between groups in the change from baseline on the Kansas City Cardiomyopathy Questionnaire total symptom score. At week 24, the change from baseline for the median N-terminal pro-B-type natriuretic peptide level was 10% lower in the omecamtiv mecarbil group than in the placebo group; the median cardiac troponin I level was 4 ng per liter higher. The frequency of cardiac ischemic and ventricular arrhythmia events was similar in the two groups. CONCLUSIONS Among patients with heart failure and a reduced ejection, those who received omecamtiv mecarbil had a lower incidence of a composite of a heart-failure event or death from cardiovascular causes than those who received placebo. (Funded by Amgen and others; GALACTIC-HF ClinicalTrials.gov number, NCT02929329; EudraCT number, 2016 -002299-28.)