1,904 research outputs found

    Did Labour fundamentally change Britain in its thirteen years of power? Hardly at all

    Get PDF
    The ‘new Labour’ governments of Tony Blair and Gordon Brown altered the societal landscape in the UK. But did they fundamentally change Britain? In a new book, David Walker and Polly Toynbee take an in-depth and balanced look at the achievements of the Labour project. There were some policy successes, and the authors give Labour 6 out of 10 for these. Yet the party lacked an overall vision or narrative, and so squandered its opportunity to push the UK in a more social democratic directio

    TMEM67 is required for the maintenance of the perinuclear actin cap

    Get PDF
    Meckel-Gruber syndrome (MKS) is a genetically heterogeneous disease characterised by the phenotypic triad of occipital encephalocele, polycystic kidneys, and polydactyly. MKS is classified as a ciliopathy as mutations to the MKS proteins result in dysfunction to the primary cilium. Recent research has expanded the aetiology of MKS, as increasing evidence for non-ciliary roles for the MKS proteins are uncovered. Evidence includes their presence at focal adhesions and a role in controlling extracellular matrix (ECM) morphology. The relative contributions of ciliary and non-ciliary cellular phenotypes to the clinical presentations of MKS are not currently known. This thesis identifies ECM-dependent aberrations to the perinuclear actin cap in MKS patient cells lacking the MKS type 3 transmembrane protein TMEM67, likely contributing to migration defects previously identified in patient cells. Furthermore, GFP-Trap analysis identifies a number of myosins as potential binding partners of TMEM67; a previously unreported association. Analysis of these binding partners reports the top biological processes for TMEM67 as myosin-motor activity and actin-based movement, adding to the potential non-ciliary roles of the protein already reported. By expanding our understanding of the role of ciliopathy proteins outside of the cilium, we better comprehend the aetiology of the diseases, providing an opportunity to find new therapeutic interventions

    Race, consecration and the music outside? The making of the British jazz avant-garde 1968-1973

    Get PDF
    No abstract available

    Gordon Brown's misplaced Smithian appeal : the eclipse of sympathy in changing British welfare norms

    Get PDF
    Gordon Brown has eagerly lauded his fellow Kirkcaldy citizen, Adam Smith, as his main policy inspiration. This article tests the rigour of such a claim by matching Brown's promotion of Smithian ‘sympathy’ as the centrepiece of his programme for government with the changes introduced by his Treasury to the British welfare model. In the 1970s, Thomas Wilson showed that the traditions of the post-war British welfare state were compatible with a modified form of Smithian sympathy socialised at the level of the state. New Labour has set about reforming the welfare model with respect to both its underlying institutions and the basic subjectivities of its recipients. I show that Brown's substantive preference for an asset-based system of welfare moves those subjectivities away from the ‘relational self’ of Smithian sympathy and towards a much more ‘autonomous self’. Consequently, I conclude that it is stretching Smith's concept of sympathy too far, even in a modified socialised form, to associate it with New Labour's asset-based system of welfare

    Ideology: towards renewal of a critical concept

    Get PDF
    In this response to our critics and fellow-travellers we reaffirm our claim that contemporary media studies should reinvent a critical concept of ideology. We do this through addressing some of the problems with older critical conceptions of ideology and suggesting potentially fruitful ways forward through engaging with research traditions that have become neglected or are overlooked in the field. This avowedly inter-disciplinary position draws on political philosophy, critical realism, ordinary language philosophy, and discursive psychology. At the end of the essay we show how a critical concept of ideology can be applied in analysis of news reporting

    Aesthetic labour, emotional labour and masculinity

    Get PDF
    This special issue of the journal focuses on the topic of service work and gender. The theme for this special issue arose out of a stream on service work and gender at the 2005 Gender Work and Organization conference. In many respects this special edition can be considered as complementary to an earlier special edition on gender and service work that came out in 2005. In the editorial for the 2005 special edition Kerfoot and Korczynski raised a number of issues, questions and points for debate. It is worth briefly reprising some of these here as in many respects they provide a point of departure for a number of the concerns of this particular special edition

    Firm-Manager Matching and the Tradeoffs of CFO Accounting Expertise

    Get PDF
    We examine the tradeoffs of CFO accounting expertise and their role in firm-manager matching decisions. Although prior work examines the positive effects of accounting expertise on several financial reporting outcomes, there is little evidence on the tradeoffs this expertise entails, much less how firms compensate for these tradeoffs. We conjecture that acquiring accounting expertise requires costly tradeoffs in terms of acquiring other skills, including operational knowledge and strategic expertise. We find that these tradeoffs are reflected in firms’ hiring decisions ex ante and affect several ex post employment decisions. Collectively, the results suggest accounting expertise is a carefully weighed attribute of CFO hires that shapes and is shaped by the composition of the top management team
    corecore