73 research outputs found
Does practicing hatha yoga satisfy recommendations for intensity of physical activity which improves and maintains health and cardiovascular fitness?
- Author
- A Damodaran
- A Mogra
- AC King
- Andrew Rundle
- B Sinha
- BE Ainsworth
- BKS Iyengar
- C Lakshmikanthan
- C Patel
- C Patel
- C Patel
- CA Macera
- CB Taylor
- CC Clay
- D Labarthe
- DR Dengel
- H Tanaka
- IM Lee
- J Carroll
- J Yogendra
- JA Cusumano
- JA Raub
- JF Sallis
- JM Hagberg
- JN Morris
- JP Despres
- JP Despres
- JS Naruka
- JS Reitman
- K Chandler
- K Harinath
- K Zhang
- KE Innes
- KE Powell
- KK Latha
- KN Udupa
- KVV Prasad
- L Rai
- L Rai
- LJ DiCarlo
- M Garfinkel
- MA Gimbel
- Marshall Hagins
- MD Brown
- MD Tran
- ML Gaesser Pollock
- ML Pollock
- N Aaronson
- OP Bagga
- R Anantharaman
- R Funderburg Corliss
- R Monro
- R Vyas
- RB Saper
- RS Paffenbarger Jr.
- S Joseph
- S Rao
- S Telles
- SB Heymsfield
- SN Blair
- SP Helmrich
- SR Cummings
- T Schmidt
- TJ Angelopoulos
- US Ray
- US Ray
- V Malhotra
- W Selvamurthy
- Wendy Moore
- WL Haskell
- Y Oshida
- Publication venue
- BioMed Central
- Publication date
- 01/01/2007
- Field of study
Background: Little is known about the metabolic and heart rate responses to a typical hatha yoga session. The purposes of this study were 1) to determine whether a typical yoga practice using various postures meets the current recommendations for levels of physical activity required to improve and maintain health and cardiovascular fitness; 2) to determine the reliability of metabolic costs of yoga across sessions; 3) to compare the metabolic costs of yoga practice to those of treadmill walking. Methods: In this observational study, 20 intermediate-to-advanced level yoga practitioners, age 31.4 ± 8.3 years, performed an exercise routine inside a human respiratory chamber (indirect calorimeter) while wearing heart rate monitors. The exercise routine consisted of 30 minutes of sitting, 56 minutes of beginner-level hatha yoga administered by video, and 10 minutes of treadmill walking at 3.2 and 4.8 kph each. Measures were mean oxygen consumption (VO2), heart rate (HR), percentage predicted maximal heart rate (%MHR), metabolic equivalents (METs), and energy expenditure (kcal). Seven subjects repeated the protocol so that measurement reliability could be established. Results: Mean values across the entire yoga session for VO2, HR, %MHR, METs, and energy/min were 0.6 L/kg/min; 93.2 beats/min; 49.4%; 2.5; and 3.2 kcal/min; respectively. Results of the ICCs (2,1) for mean values across the entire yoga session for kcal, METs, and %MHR were 0.979 and 0.973, and 0.865, respectively. Conclusion: Metabolic costs of yoga averaged across the entire session represent low levels of physical activity, are similar to walking on a treadmill at 3.2 kph, and do not meet recommendations for levels of physical activity for improving or maintaining health or cardiovascular fitness. Yoga practice incorporating sun salutation postures exceeding the minimum bout of 10 minutes may contribute some portion of sufficiently intense physical activity to improve cardio-respiratory fitness in unfit or sedentary individuals. The measurement of energy expenditure across yoga sessions is highly reliable
Pan-cancer analysis of whole genomes
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- T. vk
- T. vl
- T. vv
- T. xh
- T. xo
- T. yw
- T. z yc
- T. zx
- Tam
- Tamborero
- Tan
- Tan D. v
- Tanaka
- Tanskanen
- Tarnuzzer
- Tarpey
- Taschuk M. L. n
- Tatsuno
- Tavaré
- Tembe
- Temes
- Thai K. n
- Thayer
- The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium View Correspondence (jump link)
- Thiessen
- Thomas
- Thomas
- Thompson
- Thompson
- Thompson
- Thorne
- Thorne
- Thorogood
- Tijanic
- Timms
- Tirabosco
- tj Sweep
- Tojo
- Tommasi
- Toon
- Toprak
- Torrents
- Tortora
- Tost
- Totoki
- Townend
- Townend
- tp Tutt
- Traficante
- Treilleux
- Tsao
- tt Mantovani-Löffler
- tt Zenz
- tu tv
- Tubio
- Tucker
- Turkington
- Turner
- Turner
- tv tw
- tw Rohde
- U. abp
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- Ueno
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- Underwood
- Urban L. f
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- us Trümper
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- uu Lehrach
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- V. k Collins
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- van de Vijver
- Van Den Berg
- Van den Eynden
- Van der Kwast
- van Deurzen
- Van Laere
- Van Loo
- Van Meir
- van’t Veer
- Vasudev
- Vazquez
- vb Simon
- vd Biswas
- Vedururu
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- Vembu
- Vermeulen
- Verrill
- Viari
- Vicente
- Vicentini
- Vilain
- Villasante
- Vincent-Salomon
- vo Taniguchi
- Voet D. b
- von Kalle
- von Mering
- vq Yamamoto
- vx Ong
- Vyas
- Vázquez-García
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- Waddell
- Waddell
- Wadi L. k
- Wagener
- Wang
- Wang
- Wang
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- Wang
- Waring
- Warnatz
- Warrell
- Warren
- Weichenhan
- Weinberger
- Weinstein
- Weischenfeldt J. g
- Weisenberger
- Welch
- Wendl M. C. z
- wf Amary
- Whalley
- Wheeler
- wi Futreal
- Wigle
- Wilkerson M. D. v
- Williams
- Wilmott
- Wilson G. W. k
- Wilson R. K. z
- Wintersinger
- Wiznerowicz
- Wolf
- Wong
- Wong
- Woo
- Wood
- Wouters
- Wright
- Wright
- Wright A. J. k
- ws Ang
- Wu
- Wu
- Wu
- wv abg
- wz Hupp
- x Eils
- x Yung
- X. abp
- X. at
- X. bk
- X. cq
- X. ez
- X. ez
- X. fh
- X. fv
- X. fv
- X. fv
- X. fv
- X. k Mbabaali
- X. oi
- X. S. wd
- X. tc
- X. zv
- xb Danilova
- xb Felau
- xc Lovat
- xh Curley
- xh Fulton
- Xi
- Xia
- Xiang
- Xiong
- xo Abeshouse
- xp Benz
- xp Edwards
- xr Ghori
- xs Gundem
- Xue
- xv Luxton
- xw McDermott
- xy Visakorpi
- xz Whitaker
- Y. -E. ot
- Y. -J. k
- Y. -J. xn
- Y. abp
- Y. ae
- Y. ae
- Y. ae
- Y. ae
- Y. ai
- Y. aj
- Y. al
- Y. bk
- Y. dg
- Y. dy
- Y. ef
- Y. ep
- Y. ez
- Y. ff
- Y. fr
- Y. fv
- Y. fv
- Y. gl
- Y. hl
- Y. hq
- Y. hq
- Y. ia
- Y. kq
- Y. lw
- Y. nh
- Y. nk
- Y. nz
- Y. rg
- Y. rj
- Y. rm
- Y. S. jf
- Y. uz
- Y. vr
- Y. wt
- Y. yc
- ya Al-Ahmadie
- Yachida
- Yamaguchi
- Yamaguchi T. N. k
- Yamamoto
- Yamaue
- Yang
- Yang
- Yang
- Yang
- Yang
- Yao
- Yaspo
- Yates
- Yau
- yb Ally
- yd Cherniack
- yd Lai
- yd Schadendorf
- ye Auman
- ye Umbricht
- Yellapantula
- Yellapantula
- yh Bathe
- yj Baylin
- Yoon
- Yu
- Yu
- Yu
- Yuan
- Yugawa
- z ah
- Z. ej
- Z. ep
- Z. fr
- Z. hv
- Z. hy
- Z. jq
- Z. kt
- Z. oe
- Zaikova
- Zapatka
- zd Gershenwald
- Zenklusen
- Zeps
- zf Ghossein
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang H. b
- Zhao
- Zheng
- Zhou
- Zhou
- Zhu
- Zhu
- zi zj
- zm Jayaseelan
- Zou
- Zou
- zt Kim
- zw Lewis
- Ó. A. th
- Ø. sk
- Publication venue
- Publication date
- 11/12/2019
- Field of study
Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale(1-3). Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4-5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter(4); identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation(5,6); analyses timings and patterns of tumour evolution(7); describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity(8,9); and evaluates a range of more-specialized features of cancer genomes(8,10-18).Peer reviewe
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.
- Author
- Abigail Hynes
- Aditya Mandal
- Adrian Barnardo
- Aftab Ala
- Agostino Colli
- Alan Shepherd
- Alan Watson
- Alastair McNair
- Alberto Mattalia
- Alexandra McKay
- Alice Wright
- Alison Brind
- Alison Loftus
- Alison Paton
- Alistair King
- Allister Grant
- Altaf Palegwala
- Amir Shah
- Amit Singhal
- Ana Lleo
- Andrea Broad
- Andrea Crosignani
- Andrea Galli
- Andrew Austin
- Andrew Bathgate
- Andrew Bell
- Andrew Burroughs
- Andrew Chilton
- Andrew Davis
- Andrew Douds
- Andrew Douglass
- Andrew Fraser
- Andrew Gibbins
- Andrew Higham
- Andrew L Mason
- Andrzej Piotrowicz
- Andy Li
- Angelo Andriulli
- Anna Fouracres
- Annarosa Floreani
- Anne Eastick
- Anton Gunasekera
- Antonio Benedetti
- Antonio Picciotto
- Aruna Dias
- Ashis Mukhopadhya
- Ashley Brown
- Asifabbas Naqvi
- Athar Saeed
- Bal Shinder
- Barbara Coco
- Barbara Foglieni
- Barbara Hoeroldt
- Becky Holbrook
- Beverley Longhurst
- Bob Grover
- Brian D. Juran
- Bridget Bird
- Bridget Gunson
- Bronwen Williams
- Bruce R Bacon
- Caradog Thomas
- Carl A. Anderson
- Carlo Ferrari
- Carly Brown
- Carmela Cursaro
- Carol Thomas
- Carole Collins
- Carole Foale
- Caroline Cowley
- Caroline Hamilton
- Caroline Lawlor
- Caroline Mulvaney-Jones
- Caroline Palmer
- Carolyn MacNicol
- Caron Innes
- Casey S. Greene
- Catherine Gray
- Catherine Vincent
- Charles Grimley
- Charles Millson
- Chin Lye Ch'ng
- Chris Evans
- Chris Ford
- Christine Dickson
- Christopher Healey
- Christopher Hovell
- Christopher I. Amos
- Christopher Macdonald
- Christopher Shallcross
- Christopher Shorrock
- Claire Duggan
- Claudio Tiribelli
- Craig Lammert
- Cristina Barlassina
- Cynthia Levy
- D Williams
- Dakai Zhu
- Daniel Forton
- Daniele Cusi
- Daniele Prati
- Darren Clement
- David C. Qian
- David Elphick
- David Gorard
- David Jones
- David Neal
- David Ramanaden
- David Tyrer
- Dawn Sirdefield
- Deb Ghosh
- Debashis Das
- Delyth Braim
- Denise Gocher
- Denise O'Donnell
- Dermot Gleeson
- Diane Simpson
- Domenico Alvaro
- Donna Cotterill
- Douglas Thorburn
- Earl Williams
- Eileen Marshall
- Eleanor Dungca
- Elizabeth J Atkinson
- Elizabeth Tanqueray
- Elva Wilhelmsen
- Emily Archer
- Emma Durant
- Emma Grieve
- Emma Gunter
- Erik M Schlicht
- Ervin Shpuza
- Estelle Nambela
- Esther Unitt
- Fabio Macaluso
- Fabio Marra
- Faiz Ali
- Federica Malinverno
- Filomena Morisco
- Fiona Gordon
- Fiona Wright
- Floriano Rosina
- Florin Muscariu
- Frances Hines
- Francesca Bernuzzi
- Gang Xie
- Gary Bray
- Gayle Clifford
- Geeta Prasad
- George Abouda
- George Bird
- George F. Mells
- George Lipscomb
- George MacFaul
- Giancarlo Spinzi
- Gianfranco Elia
- Gideon M. Hirschfield
- Gill Watts
- Giovanni Casella
- Glynis Stansfield
- Gordon Wood
- Graeme Alexander
- Graham Butcher
- Graham Foster
- Grazia A Niro
- Gregory Whatley
- Greta Van Duyvenvoorde
- Guan Lim
- Gwen Baxter
- Hannah Dewhurst
- Harriet Gordon
- Harriet Mitchison
- Heather J. Cordell
- Helen Doyle
- Helen Fairlamb
- Helen Sweeting
- Helen Wooldridge
- Hemant Gupta
- Henry C Bodenheimer Jr
- Hilary Pateman
- Howard Curtis
- Howard Klass
- Hyder Hussaini
- Hye-Jeong Lee
- Ian Drake
- Ian Gee
- Ian Gooding
- Ian Rees
- Ilaria Bianchi
- Ilaria Sogno
- Imran Patanwala
- Imroz Salam
- Isobel Amey
- Jaber Gasem
- Jacky Orpe
- Jacqueline Brighton
- James A. B. Floyd
- James Featherstone
- James Gotto
- James Neuberger
- Jane Bowles
- Jane Collier
- Jane Gitahi
- Jane Maiden
- Jane Metcalf
- Janeane Hails
- Janette Curtis
- Janie Keggans
- Janine Musselwhite
- Javaid Subhani
- Jayne Jones
- Jean Kordula
- Jeff Butterworth
- Jennie Kendall
- Jennifer Morrison
- Jeremy Shearman
- Jeremy Tibble
- Jessica Whiteman
- Jia Qu
- Jill Conder
- Jinyi Zhang
- Jo Ridpath
- Joanna Allison
- Joanna Sayer
- Jocelyn Fraser
- John Dillon
- John Mclindon
- John Ramage
- Jonathan Booth
- Jonathan Brown
- Joseph A Odin
- Joy Sadeghian
- Joy Wilkins
- Julia Maltby
- Julie Browning
- Julie Colley
- Julie Tregonning
- Juliette Verheyden
- Kapil Kapur
- Karen Hogben
- Karen Warner
- Karin Young
- Kate Martin
- Kate Ocker
- Katharine Pollock
- Katherine A. Siminovitch
- Katherine I. Morley
- Kathryn Houghton
- Katie Seward
- Katie Spurdle
- Keith Elliott
- Keith George
- Kelly Amor
- Kerenza Boulton
- Kerry Flahive
- Kevin Yoong
- Kimberley Netherton
- Kirsten Walker
- Kirsty Martin
- Konrad Koss
- Konstantinos N. Lazaridis
- LaiTing Tan
- Landon L Chan
- Leonie Grellier
- Linda Jones
- Linda Kent
- Linda March
- Lisa Morgan
- Liz Farrington
- Lizzie Stafford
- Lola Dali-kemmery
- Lorenzo Morini
- Lorraine Hankey
- Lory Saveria Crocè
- Louise Winter
- Lourdes Cumlat
- Luca Fabris
- Lucie Hobson
- Luigi Muratori
- Lyn Graves
- Lynn Currie
- Lynn O'Donohoe
- M. Eric Gershwin
- Maggie Hughes
- Mandy Carnahan
- Marco Carbone
- Marco Marzioni
- Marek Czajkowski
- Maria Consiglia Bragazzi
- Maria Francesca Donato
- Maria Hamilton
- Maria Hayes
- Maria Vinci
- Mariam Nasseri
- Marie Green
- Marie Quinn
- Marina Leoni
- Mario Strazzabosco
- Marisa Mills
- Mariza de Andrade
- Mark Ainsworth
- Mark Aldersley
- Mark Cox
- Mark Narain
- Mark Wilkinson
- Mark Wright
- Markus Gess
- Marta Spreafico
- Martin Lombard
- Martin Prince
- Martyn Carter
- Mary Crossey
- Mary Ninkovic
- Massimo Colombo
- Massimo Zuin
- Matthew Brookes
- Matthew Cowan
- Matthew Cramp
- Matthew Foxton
- Maurizia Brunetto
- Mauro Podda
- Maxton Pitcher
- Mazn Karmo
- Mcdonald Mupudzi
- Melanie Harrison
- Melanie Kent
- Mervyn Davies
- Mesbah Rahman
- Metod Oblak
- Michael F. Seldin
- Michael Heneghan
- Mike Mendall
- Minesh Patel
- Mirko Tarocchi
- Mohamed Dawwas
- Mousa Hani S
- Natalie Taylor
- Natalie Wheatley
- Neil Fisher
- Nicholas Sharer
- Nicola Lancaster
- Nikki White
- Noma Ncube
- null null
- null null
- null null
- Nurani Sivaramakrishnan
- Oza Chirag
- Paolo Muratori
- Parizade Raymode
- Patrick Goggin
- Paul Banim
- Paul Kitchen
- Paul Richardson
- Paul Southern
- Paula Townshend
- Peter Bramley
- Peter K Gregersen
- Peter Mills
- Phillipa Desousa
- Pier Maria Battezzati
- Pierluigi Toniutto
- Piero L Almasio
- Piero Portincasa
- Pietro Andreone
- Pietro Invernizzi
- Piotr Milkiewicz
- Pradeep Sanghi
- Pranab Gyawali
- PuiChing Chan
- Purushothaman Premchand
- Rachel Abrahams
- Raj Srirajaskanthan
- Ray Mathew
- Ray Shidrawi
- Rebecca Bishop
- Rebecca Casey
- Rebecca Cloudsdale
- Rebecca Jones
- Renzo Montanari
- Reuben Ayres
- Richard Aspinall
- Richard Evans
- Richard Marley
- Richard Miller
- Richard N. Sandford
- Richard Sturgess
- Robert P Myers
- Robert Przemioslo
- Roberta Lazzari
- Roger McCorry
- Roland Ede
- Roman Galaska
- Rory Harvey
- Rosanna Fontana
- Rose Damant
- Rupert Ransford
- Ruth Penn
- Saket Singhal
- Sally Batham
- Sally-Ann Rolls
- Sallyanne Pearson
- Samantha Ducker
- Sambit Sen
- Samir Vyas
- Sandra Greer
- Sanjiv Jain
- Sarah Besley
- Sarah Jones
- Sarah Thornthwaite
- Sass Levi
- Savino Bruno
- Senayon Desmennu
- Sharat Misra
- Sherill Tripoli
- Silvia Colombo
- Simon Dyer
- Simon Panter
- Simon Rushbrook
- Simon Taylor-Robinson
- Simon Whalley
- Simon Williams
- Sonia Rossi
- Sonia Tarallo
- Sophie Holder
- Stephen D Ryder
- Steve Pereira
- Steven Mann
- Stewart Campbell
- Subramaniam Ramakrishnan
- Subrata Saha
- Sue Glenn
- Sue Walsh
- Sunil Dolwani
- Susan Congreave
- Susan Gallagher
- Susan Jones
- Susan Lord
- Susan Slininger
- Sushma Saksena
- Suzie Marriott
- Syed Shaukat
- Talal Valliani
- Theodore Ngatchu
- Thiriloganathan Mathialahan
- Tim Harding
- Tobias Balschun
- Toby Delahooke
- Tom Lee
- Tom Yapp
- Tracey Shewan
- Udi Shmueli
- Valentina Liakina
- Valeria Silvestre
- Velimir A Luketic
- Victoria Lambourne
- Vincenzo O Palmieri
- Vincenzo Ronca
- Voi Shim Wong
- William Stableforth
- Yafang Li
- Yeng Ang
- Yolanda Baird
- Younghun Han
- Publication venue
- Nat Commun
- Publication date
- 01/01/2015
- Field of study
Primary biliary cirrhosis (PBC) is a classical autoimmune liver disease for which effective immunomodulatory therapy is lacking. Here we perform meta-analyses of discovery data sets from genome-wide association studies of European subjects (n=2,764 cases and 10,475 controls) followed by validation genotyping in an independent cohort (n=3,716 cases and 4,261 controls). We discover and validate six previously unknown risk loci for PBC (Pcombined<5 × 10(-8)) and used pathway analysis to identify JAK-STAT/IL12/IL27 signalling and cytokine-cytokine pathways, for which relevant therapies exist
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways
- Author
- 94
- Abigail Hynes 159
- Aditya Mandal
- Adrian Barnardo 182
- Aftab Ala 138
- Agostino Colli 45
- Alan Shepherd 213
- Alan Watson 81
- Alastair McNair 175
- Alberto Mattalia 54
- Alexandra McKay 132
- Alice Wright 245
- Alison Brind 294
- Alison Loftus 91
- Alison Paton 119
- Alistair King
- Allister Grant
- Almasio 33 Piero L.
- Altaf Palegwala 98
- Amir Shah 189
- Amit Singhal
- Amos 2 Christopher I.
- Ana Lleo 12
- Anderson 8 Carl A.
- Andrea Broad 139
- Andrea Crosignani 39
- Andrew Austin 119
- Andrew Bell 305
- Andrew Burroughs 249
- Andrew Chilton 166
- Andrew Douds 243
- Andrew Gibbins 122
- Andrew Higham 293
- Andrew Bathgate
- Andrew Davis
- Andrew Douglass
- Andrew Fraser
- Andrzej Piotrowicz
- Andy Li 303
- Angelo Andriulli 37
- Anna Fouracres 247
- Annarosa Floreani 51
- Anne Eastick
- Anton Gunasekera
- Antonio Benedetti 40
- Antonio Picciotto 59
- Aruna Dias 82
- Ashis Mukhopadhya
- Ashley Brown
- Asifabbas Naqvi
- Athar Saeed 139
- Atkinson 19 Elizabeth J.
- Bacon 28 Bruce R.
- Bal Shinder 258
- Barbara Coco 43
- Barbara Foglieni 11
- Barbara Hoeroldt 244
- Becky Holbrook 222
- Beverley Longhurst 240
- Bob Grover 151
- Bodenheimer Jr 29 Henry C.
- Bridget Bird 191
- Bridget Gunson 287
- Bronwen Williams
- Caradog Thomas
- Carlo Ferrari 49
- Carly Brown 270
- Carmela Cursaro 36
- Carol Thomas 156
- Carole Collins 300
- Carole Foale 138
- Caroline Cowley 182
- Caroline Mulvaney Jones
- Caroline Hamilton
- Caroline Lawlor
- Caroline Palmer
- Carolyn MacNicol 163
- Caron Innes
- Catherine Vincent 31
- Catherine Gray
- Chan 19 Landon L.
- Charles Grimley
- Charles Millson
- Chin Lye Ch’
- Chris Evans 190
- Chris Ford
- Christine Dickson 239
- Christopher Healey 71
- Christopher Hovell 122
- Christopher Shorrock 90
- Christopher Shallcross
- Claire Duggan 159
- Claudio Tiribelli 48
- Cordell Heather J.
- Craig Lammert 7
- Cristina Barlassina 38
- Cynthia Levy 32
- Dakai Zhu 2
- Daniel Forton 275
- Daniele Prati 11
- Daniele Cusi
- Darren Clement 294
- David Elphick 106
- David Jones 188
- David Ramanaden 86
- David Tyrer 252
- David Gorard
- David Neal
- Dawn Sirdefield
- Deb Ghosh
- Debasish Das 166
- Delyth Braim
- Denise Gocher 289
- Denise O’
- Dermot Gleeson
- Diane Simpson 239
- Domenico Alvaro 35
- Donna Cotterill 305
- Douglas Thorburn 249
- Earl Williams 246
- Eileen Marshall 249
- Eleanor Dungca 107
- Elizabeth Tanqueray 221
- Elva Wilhelmsen 165
- Emily Archer 271
- Emma Grieve 196
- Emma Gunter 246
- Emma Durant
- Eric Gershwin 15 M.
- Ervin Shpuza
- Estelle Nambela
- Esther Unitt 289
- Fabio Macaluso 34
- Faiz Ali 156
- Federica Malinverno 46
- Filomena Morisco 57
- Fiona Gordon 288
- Fiona Wright 189
- Floriano Rosina 60
- Florin Muscariu
- Floyd James A. B.
- Frances Hines
- Francesca Bernuzzi 41
- Galli Andrea
- Gang Xie
- Gary Bray 272
- Gayle Clifford 270
- Geeta Prasad 285
- George Lipscomb 91
- George MacFaul 187
- George Abouda
- George Bird
- Giancarlo Spinzi 61
- Gianfranco Elia 49
- Gill Watts 285
- Giovanni Casella 44
- Glynis Stansfield 163
- Gordon Wood 140
- Graeme Alexander 101
- Graham Foster 80
- Graham Butcher
- Greene Casey S.
- Gregersen Peter K.
- Gregory Whatley 280
- Greta Van Duyvenvoorde 90
- Guan Lim 135
- Gwen Baxter 191
- Hannah Dewhurst 246
- Harriet Gordon 145
- Harriet Mitchison 107
- Helen Doyle 109
- Helen Wooldridge 117
- Helen Fairlamb
- Helen Sweeting
- Hemant Gupta
- Hilary Pateman
- Hirschfield Gideon M.
- Howard Curtis
- Howard Klass
- Hyder Hussaini 247
- Hye Jeong Lee 167
- Ian Gooding 108
- Ian Rees 157
- Ian Drake
- Ian Gee
- Ilaria Bianchi 41
- Ilaria Sogno 41
- Imran Patanwala 252
- Imroz Salam 158
- Isobel Amey 304
- Jaber Gasem 87
- Jacky Orpe 256
- Jacqueline Brighton 138
- James Featherstone 147
- James Gotto 314
- James Neuberger 287
- Jane Bowles 318
- Jane Collier 231
- Jane Gitahi 288
- Jane Maiden 98
- Jane Metcalf
- Janeane Hails 101
- Janette Curtis 278
- Janie Keggans 191
- Janine Musselwhite
- Javaid Subhani 83
- Jayne Jones 260
- Jean Kordula
- Jeff Butterworth
- Jennie Kendall
- Jennifer Morrison 222
- Jeremy Shearman 271
- Jeremy Tibble 93
- Jessica Whiteman
- Jia Qu 25
- Jill Conder 293
- Jinyi Zhang 23
- Jo Ridpath 147
- Joanna Allison
- Joanna Sayer
- Jocelyn Fraser 304
- John Dillon 214
- John Ramage 146
- John Mclindon
- Jonathan Booth 245
- Jonathan Brown
- Joy Sadeghian 153
- Joy Wilkins 164
- Julia Maltby 253
- Julie Colley 258
- Julie Browning
- Julie Tregonning
- Juliette Verheyden
- Juran 7 Brian D.
- Kapil Kapur 79
- Karen Hogben 122
- Karen Warner
- Karin Young 196
- Kate Martin 252
- Kate Ocker 199
- Katharine Pollock
- Kathryn Houghton 188
- Katie Seward 92
- Katie Spurdle
- Keith Elliott 79
- Keith George 265
- Kelly Amor 255
- Kerenza Boulton 265
- Kerry Flahive 140
- Kevin Yoong 183
- Kimberley Netherton 283
- Kirsten Walker
- Kirsty Martin
- Konrad Koss 126
- LaiTing Tan 135
- Lazaridis 7 Konstantinos N.
- Leonie Grellier 164
- Linda Jones 245
- Linda March 238
- Linda Kent
- Lisa Morgan 302
- Liz Farrington 247
- Lizzie Stafford 231
- Lola Dali kemmery 253
- Lorenzo Morini 56
- Lorraine Hankey 122
- Lory Saveria Croce ` 48
- Louise Winter 312
- Lourdes Cumlat 306
- Luca Fabris 50
- Lucie Hobson
- Luigi Muratori 36
- Luketic 27 Velimir A.
- Lyn Graves 247
- Lynn Currie
- Lynn O’
- Maggie Hughes
- Mandy Carnahan
- Marco Carbone 101
- Marco Marzioni 40
- Marek Czajkowski
- Maria Consiglia Bragazzi 42
- Maria Francesca Donato 46
- Maria Hayes 240
- Maria Vinci 65
- Maria Hamilton
- Mariam Nasseri 151
- Marie Green 254
- Marie Quinn 303
- Marina Leoni 249
- Mario Strazzabosco
- Marisa Mills 260
- Mariza de Andrade 19
- Mark Ainsworth 231
- Mark Cox 295
- Mark Narain 159
- Mark Wright 286
- Mark Aldersley
- Mark Wilkinson
- Markus Gess 170
- Marra Fabio
- Marta Spreafico 11
- Martin Lombard 252
- Martin Prince 104
- Martyn Carter
- Mary Crossey
- Mary Ninkovic
- Mason 21 Andrew L.
- Massimo Colombo 46
- Massimo Zuin
- Matthew Brookes 254
- Matthew Cowan 279
- Matthew Cramp 238
- Matthew Foxton 105
- Maurizia Brunetto 43
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- Siminovitch Katherine A.
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- Yafang Li
- Yeng Ang 312
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- Younghun Han
- Publication venue
- Publication date
- 01/01/2015
- Field of study
Recommended from our members
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
- Author
- Aaltonen L. A.
- Abascal F.
- Abeshouse A.
- Aburatani H.
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- Zou L.
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- Publication venue
- Springer Science and Business Media LLC
- Publication date
- 02/03/2020
- Field of study
Chromothripsis is a mutational phenomenon characterized by massive, clustered genomic rearrangements that occurs in cancer and other diseases. Recent studies in selected cancer types have suggested that chromothripsis may be more common than initially inferred from low-resolution copy-number data. Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA), we analyze patterns of chromothripsis across 2,658 tumors from 38 cancer types using whole-genome sequencing data. We find that chromothripsis events are pervasive across cancers, with a frequency of more than 50% in several cancer types. Whereas canonical chromothripsis profiles display oscillations between two copy-number states, a considerable fraction of events involve multiple chromosomes and additional structural alterations. In addition to non-homologous end joining, we detect signatures of replication-associated processes and templated insertions. Chromothripsis contributes to oncogene amplification and to inactivation of genes such as mismatch-repair-related genes. These findings show that chromothripsis is a major process that drives genome evolution in human cancer
Corrigendum to ‘An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs’ [J Hepatol 2021;75(3):572–581]
- Author
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- Abecasis G
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- Abouda G
- Affronti A
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- Aldersley M
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- Atkinson EJ
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- Austin A
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- Bai X
- Balasubramanian S
- Banim P
- Baras A
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- Barclay ST
- Barnard L
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- Bathgate AJ
- Battezzati PM
- Beckley M
- Beechert C
- Bell A
- Benedetti A
- Bhalme M
- Bird G
- Blumenfeld A
- Bob Grover VP
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- Bragazzi MC
- Bramley P
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- Butcher G
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- Calvaruso V
- Cantor M
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- Carter MJ
- Casella G
- Cazzagon N
- Ch'ng CL
- Chalasani N
- Chayama K
- Cheent K
- Cheung A
- Cheung A
- Chopra K
- Christie J
- Ciaccio A
- Coco B
- Colli A
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- Collins CE
- Colloredo G
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- Colombo S
- Coppola G
- Corbett C
- Cordell HJ
- Corless L
- Cowan M
- Cox M
- Cramp ME
- Cristoferi L
- Crocè LS
- Crosignani A
- Cursaro C
- Curtis H
- Darlay R
- Das D
- Das D
- Davis A
- De Andrade M
- De Andrade M
- Dillon JF
- Donato F
- Douds AC
- Douglass A
- D’Amato D
- Ebinuma H
- Economides A
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- Jones DE
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- Juran BD
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- Shuldiner A
- Siminovitch KA
- Siminovitch KA
- Singhal S
- Sivaramakrishnan NN
- Soejima Y
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- Takaki A
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- Takeyama Y
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- Taylor-Robinson S
- Thomson SJ
- Thorburn D
- Tibble JA
- Tidbury J
- Tiribelli C
- Tokunaga K
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- Toniutto P
- Trivedi P
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- Tsuruta S
- Uemoto S
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- Umemura T
- Unitt E
- Valenti L
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- Vincent C
- Vinci M
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- Walker G
- Watanabe Y
- Wesley E
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- Whatley GCA
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- Wilkins J
- Williams E
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- Publication venue
- 'Elsevier BV'
- Publication date
- 08/11/2021
- Field of study
Institutional delivery in public and private sectors in South Asia: a comparative analysis of prospective data from four demographic surveillance sites
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- A Costa De
- A Harding
- A Mills
- A Pradhan
- Abdul Kuddus
- AJ Kesterton
- AM Pomeroy
- AS Teferra
- B Alam
- B McPake
- Bhim Prasad Shrestha
- BP Shrestha
- BW Bellows
- CR Ergler
- D Filmer
- D Govil
- D Montagu
- David Osrin
- Dharma S. Manandhar
- DR Hotchkiss
- E Fottrell
- E Saroha
- E Tung
- G Abeje
- G Afful-Mensah
- G Alcock
- Glyn Alcock
- Government of India Ministry of Health and Family Welfare
- I Anwar
- I Anwar
- International Institute for Population Sciences
- International Institute for Population Sciences
- J Bhatia
- J-O Schmidt
- K Azad
- Kishwar Azad
- KR Nayar
- L Say
- M Mackintosh
- M Mohanan
- M Tsawe
- Ministry of Health and Family Welfare
- Ministry of Health and Family Welfare
- Ministry of Health and Family Welfare
- Ministry of Health and Family Welfare
- Ministry of Health and Population
- Ministry of Health and Population New ERA, ICF International
- N Chakraborty
- N Islam
- N Kamal
- N Shah More
- N Shah More
- N Shah More
- Naomi Saville
- National Institute of Population Research and Training (NIPORT) Mitra and Associates, ICF International
- National Institute of Population Research and Training (NIPORT) Mitra and Associates, ICF International
- Neena Shah More
- Nirmala Nair
- NP Tey
- P Jeffery
- P Tripathy
- PK Singh
- R Morgan
- R Njuki
- RK Sinha
- RR Wagle
- S Ahmed
- S Ahmed
- S Basu
- S Dhakal
- S Dutta
- S Gabrysch
- S Kumar
- S Maiti
- S Prinja
- S Sarbani Roy
- S Vyas
- S Witter
- SB Agha
- Shibanand Rath
- SM Ahmed
- SN Mitra
- SR Sharma
- SS Lim
- Sushmita Das
- T Abuya
- T Powell-Jackson
- T Powell-Jackson
- Tanja A. J. Houweling
- TR Feyissa
- TR Jat
- UN
- W Newbrander
- W Wang
- WHO UNICEF
- Y Kawakatsu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
An overview on the role of dietary phenolics for the treatment of cancers
- Author
- A Adam
- A Akk
- A Aquilato
- A Crozier
- A Ghasemzadeh
- A Rzepecka-Stojko
- AG Clark
- AK Pandurangan
- B Zhao
- B Zhu
- BF Zamarron
- C Eroglu
- C Kandaswami
- C Seidel
- CA Dinarello
- CB Oliveira de
- CM Tsai
- CS Yang
- CY Li
- CY Peng
- CZ Liang
- D Hanahan
- D Heemst van
- D Hernanz
- D Lamoral-Theys
- D Miller
- D Xiang
- DT Leicht
- E Kassi
- E Pontiki
- EL Niero
- EP Chiang
- F Ververidis
- G Dranoff
- G Pirzad
- GI Shapiro
- GM Cooper
- GW Yang
- H Davies
- H Guo
- H Kim
- HBA Lodish
- HH Ho
- HH Lin
- HM Chen
- HP Lin
- HP Lin
- I Martinez-Valverde
- I Onakpoya
- IC Arts
- J Dai
- J Mursu
- J Perez-Jimenez
- JA Nilsson
- JD Lambert
- JP Spencer
- JT Sanderson
- JY Zhu
- K Kessenbrock
- K Pei
- K Rahman
- K Raina
- K Rajalakshmi
- KA Sarosiek
- KB Pandey
- KC Pramanik
- KE Heim
- L Letenneur
- L Marin
- LA Pacheco-Palencia
- LC Wang
- LD Murad
- LS Panizzi
- M Chen
- M Cheung
- M D’Archivio
- M Fukuda
- M Hirose
- M Kivilompolo
- M Rossetto
- M Valdez-Morales
- Manjunatha G. Vimalambike
- MB Sporn
- MC Yin
- MP Murphy
- MW Hung
- MY Chang
- N Niho
- N Rajendra Prasad
- N Wajapeyee
- NJ Kang
- NS Khan
- P Andrikopoulos
- P Annamalai
- P Davalli
- P De
- P Onori
- P Saha
- PD Ray
- Prathima C. Gowda
- Preethi G. Anantharaju
- PV Turner
- R Kurata
- R Tsao
- RJ Liu
- S Benedetti
- S Budavari
- S Elmore
- S Kakkar
- S Khadem
- S Kumar
- S Samarghandian
- S Shahrzad
- S Shailasree
- SK Jaganathan
- SK Jaganathan
- SM Kern
- SM Tsao
- SP Fraser
- SR Kim
- SS Gill
- SubbaRao V. Madhunapantula
- T Nagaoka
- T Senawong
- T Vogt
- TW Chung
- U Fahrioglu
- U Vyas
- V Cheynier
- V Habauzit
- V Tzin
- W Russell
- W-K Shon
- WC Chang
- WSM Mao
- WY Huang
- X Zhang
- X-F Lin
- XE Guo
- Y Konishi
- Y Konishi
- Y Nakabeppu
- YJ Lee
- YJ Lee
- YP Devi
- Z Kyselova
- Z Nikitaki
- Z Quinde-Axtell
- Z Sourani
- ZC Ma
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
- Author
- A Gordon Robertson
- Abdullah Kahraman
- Abel Gonzalez-Perez
- Adam A Margolin
- Adam Abeshouse
- Adam Grundhoff
- Adam J Struck
- Adam J Struck
- Adam J Wright
- Adam Lambert
- Adam P Butler
- Adam P Butler
- Adel El-Naggar
- Adnan M Nagrial
- Adrian Ally
- Adrian Baez-Ortega
- Adrian Thorogood
- Adriana Salcedo
- Adrienne M Flanagan
- Ake Borg
- Akihiro Fujimoto
- Akihiro Suzuki
- Akinyemi I Ojesina
- Alain Viari
- Alan J Robertson
- Alan P Hoyle
- Alan Thompson
- Alasdair Stenhouse
- Alastair M Thompson
- Aldo Scarpa
- Alessandro Pastore
- Alex Buchanan
- Alex Buchanan
- Alexander Claviez
- Alexander J Lazar
- Alexander Martinez-Fundichely
- Alfonso Muñoz
- Alfonso Valencia
- Aliaksei Z Holik
- Alice Meng
- Alicia L Bruzos
- Allison Creason
- Allison P Heath
- Alvin Wei Tian Ng
- Alvis Brazma
- Amaro Taylor-Weiner
- Amber L Johns
- Amie Radenbaugh
- Amit G Deshwar
- Ana Dueso-Barroso
- Ana Mijalkovic Mijalkovic-Lazic
- Ana Milovanovic
- Ana Milovanovic
- Andre Kahles
- Andrea Haake
- Andrea Holbrook
- Andrea L Richardson
- Andrea Mafficini
- Andrea Ruzzenente
- Andreas Behren
- Andreas Rosenwald
- Andreia V Pinho
- Andrew Berchuck
- Andrew D Cherniack
- Andrew J Dunford
- Andrew J Mungall
- Andrew J Spillane
- Andrew Menzies
- Andrew Menzies
- Andrew P Barbour
- Andrew Tutt
- Andrew V Biankin
- Andrey Korshunov
- Andrés Lanzós
- Andy Cafferkey
- Andy G Lynch
- Angela Chou
- Angela N Brooks
- Angela Tam
- Angelica Ochoa
- Angelika N Christ
- Angelo P Dei Tos
- Anieta M Sieuwerts
- Anil K Sood
- Anita Langerød
- Anja Füllgrabe
- Anke K Bergmann
- Ann-Marie Patch
- Anna deFazio
- Anna Ehinger
- Anna Fitzgerald
- Anne Hamilton
- Anne Vincent-Salomon
- Anne Y Warren
- Anne-Lise Børresen-Dale
- Annegien Broeks
- Anthony DiBiase
- Anthony J Gill
- Anthony Ng
- Anthony R Green
- Antonia L Pritchard
- Antonio Pea
- Antonios Koures
- Aparna Prasad
- Apurva M Hegde
- Aquila Fatima
- Arcadi Navarro
- Arie B Brinkman
- Arif O Harmanci
- Arindam Maitra
- Armando Lopez-Guillermo
- Arndt Borkhardt
- Arnoud Boot
- Asger Hobolth
- Ashley Williams
- Ashton A Connor
- Atul J Butte
- Aurélien Chateigner
- Austin J Hepperla
- Axel Aretz
- Aya Sasaki-Oku
- Ayellet V Segre
- B F Francis Ouellette
- Bailey Matthew H
- Barbara Hutter
- Barbara Hutter
- Barbara Kremeyer
- Bartha M Knoppers
- Beifang Niu
- Beifang Niu
- Beifang Niu
- Benedikt Brors
- Benita Kiat Tee Tan
- Benjamin J Raphael
- Benjamin P Berman
- Benjamin Raeder
- Bernardo Rodriguez-Martin
- Bernhard Radlwimmer
- Bernice H Wong
- Beth Karlan
- Bin Tean Teh
- Bin Zhu
- Birgit Burkhardt
- Bishoy M Faltas
- Bodil Bjerkehagen
- Bogdan Czerniak
- Boris Winterhoff
- Borislav C Rusev
- Bradly G Wouters
- Brandi N Davis-Dusenbery
- Brian Craft
- Brian D O'Connor
- Brian Patrick O'Neill
- Brice Aminou
- Calvin Wing Yiu Chan
- Cameron M Soulette
- Carl Herrmann
- Carl Morrison
- Carlo Gambacorti-Passerini
- Carlos Caldas
- Carlos D Bustamante
- Carlos López-Otín
- Carlota Rubio-Perez
- Carmen Gomez
- Carolien H M van Deurzen
- Carolyn M Hutter
- Carolyn M Hutter
- Carrie Cibulskis
- Caterina Vicentini
- Catherine A Shang
- Catherine D Moser
- Catherine J Kennedy
- Catrina C Fronick
- Chad J Creighton
- Chandra Sekhar Pedamallu
- Chang Li
- Charles David Imbusch
- Charles M Perou
- Charles Saller
- Charles Short
- Charlie E Massie
- Chawalit Pairojkul
- Chen Hong
- Chen Ye
- Cheng-Zhong Zhang
- Chin-Lee Wu
- Chip Stewart
- Chip Stewart
- Chip Stewart
- Choon Kiat Ong
- Chris Lawerenz
- Chris Mitchell
- Chris Sander
- Christian von Mering
- Christiane Buchholz
- Christina K Yung
- Christina K Yung
- Christina Yau
- Christine A Iacobuzio-Donahue
- Christine Chomienne
- Christine Desmedt
- Christine P'ng
- Christof von Kalle
- Christoph Borst
- Christoph Plass
- Christopher A Miller
- Christopher Benz
- Christopher J Scarlett
- Christopher J Yoon
- Christopher K Wong
- Christopher M Lalansingh
- Christopher M Lalansingh
- Christopher Ogden
- Christopher S Foster
- Christopher Umbricht
- Christopher W Toon
- Christos Sotiriou
- Cindy Bell
- Cinzia Cantù
- Ciyue Shen
- Claes Wadelius
- Clare Verrill
- Clarissa Gerhauser
- Claudia Calabrese
- Claudio Bassi
- Claudio Luchini
- Claudiu Farcas
- Clemency Jolly
- Colin A Purdie
- Colin A Semple
- Colin C Collins
- Colin S Cooper
- Conrad R Leonard
- Constance H Li
- Corbin D Jones
- Craig Shriver
- Cristina López
- Cyriac Kandoth
- Cyril Fisher
- D Neil Hayes
- Dai-Ying Wu
- Daiming Fan
- Daisuke Komura
- Dale W Garsed
- Daniel A Leongamornlert
- Daniel Baumhoer
- Daniel Hübschmann
- Daniel J Turner
- Daniel J Weisenberger
- Daniel M Berney
- Daniel Rosebrock
- Daniel S Brewer
- Daniela S Gerhard
- Danielle Pasternack
- Darell Bigner
- Dariush Etemadmoghadam
- Darlene Lee
- Darrin F Taylor
- Dave Larson
- David A Wheeler
- David A Wheeler
- David C Wedge
- David Craft
- David D L Bowtell
- David E Neal
- David Haan
- David Haussler
- David Haussler
- David Hedley
- David Huntsman
- David I Heiman
- David J Adams
- David J Van Den Berg
- David K Chang
- David K Miller
- David Khoo
- David Mutch
- David N Louis
- David Nicol
- David Ocana
- David R Jones
- David R Jones
- David Scott
- David T Bowen
- David T W Jones
- David Tamborero
- David Torrents
- David Torrents
- David Townend
- David Vicente
- Davide Antonello
- Declan Cahill
- Denis Larsimont
- Denis Yuen
- Denise Brooks
- Deniz Demircioğlu
- Dennis C Sgroi
- Dennis Karsch
- Dennis T Maglinte
- Dennis Wigle
- Derek W Wright
- Dianne E Chadwick
- Dido Lenze
- Dieter Kube
- Dieter Weichenhan
- Dilip D Giri
- Dimitri Livitz
- Dimitri Livitz
- Dimple Chakravarty
- Ding
- Dirk Schadendorf
- Dmitry A Gordenin
- Dominik Glodzik
- Don Chalmers
- Dong Guanlan
- Dongbing Liu
- Donghoon Lee
- Donghui Tan
- Donna M Muzny
- Dorthe Grabau
- Douglas A Levine
- Douglas F Easton
- Douglas Voet
- Duncan Beardsmore
- Dursi Lewis Jonathan
- Edward W Rowe
- Eigo Shimizu
- Ekta Khurana
- Elaine R Mardis
- Electron Kebebew
- Elena Piñeiro-Yáñez
- Elena Provenzano
- Elias Campo
- Elisabet Barrera
- Elisabetta Sereni
- Elizabeth A Musgrove
- Elizabeth L Appelbaum
- Elizabeth L Christie
- Elli Papaemmanuil
- Ellrott Kyle
- Emilie Lalonde
- Eoghan Harrington
- Eric Chuah
- Eric Green
- Eric Lander
- Eric Minwei Liu
- Eric Z Ma
- Eric Z Ma
- Erik Garrison
- Erik Larsson
- Erik Mayer
- Erik N Bergstrom
- Erin Curley
- Ermin Hodzic
- Erwin G Van Meir
- Esa Pitkänen
- Esther Rheinbay
- Esther Rheinbay
- Eun Pyo Hong
- Eunjung Alice Lee
- Eva G Alvarez
- Eva Hellstrom-Lindberg
- Ewan Birney
- F Germán Rodríguez-González
- Fabien C Lamaze
- Fabien Calvo
- Fabio C P Navarro
- Faiyaz Notta
- Fan Yang
- Fan Zhang
- Faraz Hach
- Faraz Hach
- Faridah Mbabaali
- Fatima Al-Shahrour
- Federico Abascal
- Fei-Fei Liu
- Felicity Newell
- Fenglin Liu
- Fernanda Amary
- Ferran Muiños
- Florian Markowetz
- Fouad Yousif
- Francesc Muyas
- Francesco Favero
- Francisco M De La Vega
- Francisco Sanchez-Vega
- Fraser R Duthie
- Fred Sweep
- Freddie C Hamdy
- Fruzsina Molnár-Gábor
- Fumie Hosoda
- G Petur Nielsen
- G Steven Bova
- Gad Getz
- Gad Getz
- Gad Getz
- Gaetan MacGrogan
- Gaetano Finocchiaro
- Gary D Bader
- Gavin Ha
- Gavin W Wilson
- Genta Nagae
- Geoff Macintyre
- George B Hanna
- George L Mihaiescu
- Georgia Escaramis
- Georgina V Long
- Gerd Nettekoven
- German M Demidov
- German Ott
- Gerrit K Hooijer
- Gerstein Mark B
- Gert G Van den Eynden
- Getz Gad
- Ghislaine Scelo
- Giada Bonizzato
- Giampaolo Tortora
- Gilles Romieu
- Gilles Thomas
- Giovanni Marchegiani
- Gisela Mir Arnau
- Giuseppe Malleo
- Gloria M Petersen
- Gordon B Mills
- Gordon B Mills
- Gordon Saksena
- Gordon Saksena
- Gordon Saksena
- Grace Tiao
- Grace Tiao
- Graham J Mann
- Grant Sanders
- Gu Kong
- Guanming Wu
- Guido Reifenberger
- Guido Sauter
- Guillaume Bourque
- Gulietta M Pupo
- Gun Ho Jang
- Gunes Gundem
- Gunnar Rätsch
- Gurnit Atwal
- Hailei Zhang
- Haiyan Irene Li
- Han Liang
- Hana Susak
- Hans Binder
- Hans Lehrach
- Hans-Jörg Warnatz
- Hardeep K Nahal-Bose
- Hark Kyun Kim
- HarshaVardhan Doddapaneni
- Hartmut Juhl
- Harvey Pass
- Hayley C Whitaker
- Hayley J Luxton
- Hazel Burke
- Heather K Schmidt
- Heather Thorne
- Hee Jin Lee
- Heidi J Sofia
- Heidi Sofia
- Helen Davies
- Helena Kilpinen
- Helene Kretzmer
- Heng Xiong
- Henk G Stunnenberg
- Henrik Hornshøj
- Henry Lee-Six
- Hideki Ohdan
- Hidenori Ojima
- Hidewaki Nakagawa
- Hikmat Al-Ahmadie
- Hilda A Pickett
- Hirofumi Rokutan
- Hirokazu Taniguchi
- Hiroki Yamaue
- Hiroko Tanaka
- Hiromi Nakamura
- Hiroshi Aikata
- Hiroto Katoh
- Hiroyuki Aburatani
- Hitoshi Katai
- Hitoshi Nakagama
- Hojabr Kakavand
- Holger Sültmann
- Holmfridur Hilmarsdottir
- Hong Su
- Hong Xue
- Hong Xue
- Hongtu Zhu
- Hongwei Zhang
- Hongxin Zhang
- Hsiao-Wei Chen
- Huanming Yang
- Hugh Barr
- Hui Shen
- Husen M Umer
- Huy Q Dinh
- Hyung-Lae Kim
- Hyung-Lae Kim
- Hyung-Yong Kim
- Hyunghwan Kim
- Ian J Davis
- Ian Welch
- Ignacio Vázquez-García
- Ignaty Leshchiner
- Ignaty Leshchiner
- Ignaty Leshchiner
- Iker Reyes-Salazar
- Ilinca Lungu
- Ilse Rooman
- Ilya Shmulevich
- Iman Sarrafi
- Iman Sarrafi
- Ina Felau
- Ioana Cutcutache
- Irene Papatheodorou
- Irinel Popescu
- Iris Pauporté
- Iris Selander
- Isabelle Treilleux
- Isidro Cortés-Ciriano
- Ivan Borozan
- Ivana Cataldo
- Ivica Letunic
- Ivica Letunic
- Ivo Buchhalter
- Ivo Buchhalter
- Ivo G Gut
- Ivo G Gut
- Ivon Harliwong
- Izar Villasante
- Iñigo Martincorena
- J Lynn Fink
- J Robert O'Neill
- J Todd Auman
- Jaclyn Smith
- Jacqueline Boultwood
- Jacqueline E Schein
- Jaegil Kim
- Jake June-Koo Lee
- Jakob Skou Pedersen
- Jakob Skou Pedersen
- James E Haber
- James G Kench
- James Gossage
- James S Wilmott
- Jan Komorowski
- Jan O Korbel
- Janae V Simons
- Jane E Brock
- Janet S Graham
- Janet S Rader
- Jared T Simpson
- Jared T Simpson
- Jason Huse
- Jaswinder S Samra
- Javier Bartolome
- Javier Bartolomé Rodriguez
- Javier Temes
- Jean C Zenklusen
- Jean Y Yang
- Jean-Rémi Trotta
- Jeffrey A Wintersinger
- Jeffrey Boyd
- Jeffrey E Gershenwald
- Jeffrey Marks
- Jeffrey Roach
- Jenna Eagles
- Jennifer L Jennings
- Jeong-Yeon Lee
- Jeremiah A Wala
- Jeremiah A Wala
- Jeremy Chien
- Jeremy Johns
- Jerome Myers
- Jesper Lagergren
- Jessica I Hoell
- Jessica K Miller
- Ji Wan Park
- Jia Liu
- Jian Wang
- Jianhong Hu
- Jianjiong Gao
- Jianmin Wu
- Jiashan Zhang
- Jiayin Wang
- Jiayin Wang
- Jieming Chen
- Jihoon Kim
- Jill Barnholtz-Sloan
- Jillian A Hung
- Jing Zhang
- Jingchun Zhu
- Joachim Weischenfeldt
- Joachim Weischenfeldt
- Joan Frigola
- Joana Carlevaro-Fita
- Jocelyne Jacquemier
- Joel S Parker
- Johan Staaf
- Johann S De Bono
- Johanna Bertl
- Johannes Werner
- Johannes Werner
- John A Demchok
- John A Foekens
- John Bartlett
- John Busanovich
- John D McPherson
- John F Thompson
- John Letaw
- John N Weinstein
- John N Weinstein
- John R McPherson
- John V Pearson
- John W M Martens
- Jon G Jonasson
- Jon W Teague
- Jon W Teague
- Jonas Demeulemeester
- Jonathan Barenboim
- Jonathan Cebon
- Jonathan D Kay
- Jonathan Göke
- Jonathan Hinton
- Jonathan Hinton
- Jonathan Nicholson
- Jonathan R Stretch
- Jonathan Spring
- Jonathan Warrell
- Jong K Kim
- Jongsun Jung
- Jongsun Jung
- Jongwhi H Hong
- Joong-Won Park
- Jordi Deu-Pons
- Jorge Reis-Filho
- Jorge Zamora
- Jorunn E Eyfjord
- Jos Jonkers
- Jose I Martin-Subero
- Jose M C Tubio
- Jose M G Izarzugaza
- Josep L L Gelpi
- Josep L L Gelpi
- Joshua Armenia
- Joshua M Stuart
- Joshua M Stuart
- Joshy George
- José María Heredia-Genestar
- Joy C Jayaseelan
- Juergen Eils
- Juhee Lee
- Jules N A Kerssemakers
- Julia Markowski
- Julia Richter
- Julian M Hess
- Julian M Hess
- Julian M Hess
- Juliann Shih
- Julie Livingstone
- Julie M Wilson
- Jun Li
- Jun Yu
- Jung Kyoon Choi
- Junjun Zhang
- Junjun Zhang
- Juok Cho
- Juris Viksna
- Justin P Whalley
- Jyoti Nangalia
- Jörg Tost
- Jüri Reimand
- K Vijay Raghavan
- Kadir C Akdemir
- Kai Ye
- Kai Ye
- Kai Ye
- Kaixian Yu
- Kami Chiotti
- Kamna Ramakrishnan
- Kaoru Nakano
- Karen McCune
- Karen Mungall
- Karen Smith-McCune
- Karin A Oien
- Karin S Kassahn
- Karine Jegalian
- Karolina Czajka
- Karsten Rippe
- Katalin Karaszi
- Katarzyna O Sikora
- Katayoon Kasaian
- Katayoon Kasaian
- Katherine A Hoadley
- Kathleen H Burns
- Kathleen Marchal
- Kathryn Alsop
- Katia Nones
- Kazuaki Chayama
- Kazuhiro Maejima
- Kazuhiro Ohi
- Ke Yuan
- Keiran M Raine
- Keiran M Raine
- Keith A Boroevich
- Kelso Sean
- Ken Chen
- Ken Chen
- Ken Dutton-Regester
- Kenji Tatsuno
- Kenneth Aldape
- Keren Isaev
- Kerstin Haase
- Keun Soo Ahn
- Keunchil Park
- Kevin J Dawson
- Kevin Thai
- Kiejung Park
- Kin Chan
- Kiran Kumar
- Kirsten Kübler
- Kiyo Shimizu
- Kjong-Van Lehmann
- Klev Diamanti
- Koji Arihiro
- Koo Jeong Kang
- Kortine Kleinheinz
- Kortine Kleinheinz
- Kristian Cibulskis
- Kuan-Lin Huang
- Kui Wu
- Kunihito Gotoh
- Kwun M Fong
- Kyle Covington
- Kyle Covington
- Kyle Ellrott
- Kyle Ellrott
- Kyle Ellrott
- L Van't Veer
- Lara Jerman
- Lara Urban
- Lars Feuerbach
- Larsson Omberg
- Laura Planko
- Laurence B Lovat
- Laurent Arnould
- Lauri A Aaltonen
- Lawrence E Heisler
- Layla Oesper
- Lee E Timms
- Lei Song
- Leigh B Thorne
- Leng Han
- Leonidas Salichos
- Leslie Cope
- Leszek J Klimczak
- Levi Garraway
- Lewis Jonathan Dursi
- Lewis Jonathan Dursi
- Lewis R Roberts
- Li Ding
- Li Ding
- Li Ding
- Li Shantao
- Liang Wen-Wei
- Liangtao Zheng
- Lieven P C Verbeke
- Lihua Zou
- Liis Uusküla-Reimand
- Liliana Greger
- Liming Yang
- Lin Li
- Lina Sieverling
- Lina Wadi
- Lincoln D Stein
- Linda Mileshkin
- Linghua Wang
- LiRehan Akbani
- Lisa Lype
- Lisa Mirabello
- Lisle E Mose
- Liu Xi
- Liu Xi
- Lixing Yang
- Lora Lewis
- Lorenz H P Trümper
- Loretta M S Lau
- Lori Boice
- Loris Mularoni
- Lorraine A Chantrill
- Louis Letourneau
- Luc Dirix
- Luca Landoni
- Luca Malcovati
- Lucas Lochovsky
- Lucila Ohno-Machado
- Lucinda A Fulton
- Lucy Matthews
- Lucy Stebbings
- Lucy Stebbings
- Lucy Yates
- Ludmil B Alexandrov
- Ludmila Danilova
- Luisa Mantovani-Löffler
- Luke Marsden
- Maciej Wiznerowicz
- Malcolm Brock
- Malcolm J Moore
- Malene Juul
- Malik Alawi
- Mamoru Kato
- Manasa Ramakrishna
- Manaswi Gupta
- Manolis Kellis
- Manuel Prinz
- Mara Rosenberg
- Marat D Kazanov
- Marc D Perry
- Marc D Perry
- Marc J van de Vijver
- Marc Zapatka
- Marcel Kool
- Marcel Smid
- Marcin Imielinski
- Marco A Marra
- Marco Miotto
- Marcus Bosenberg
- Marek Cmero
- Maria Elisabeth Goebler
- Maria Keays
- Maria O'Donovan
- Maria Scardoni
- Maria Vittoria Davi
- Marie-Laure Yaspo
- Marina Pajic
- Mario Berrios
- Mario Cazzola
- Marius Rohde
- Mark A Rubin
- Mark B Gerstein
- Mark B Gerstein
- Mark H Wright
- Mark Lathrop
- Mark P Hamilton
- Mark Phillips
- Mark Pinese
- Mark Shackleton
- Markus B Schilhabel
- Markus Kreuz
- Markus Loeffler
- Markus Ringnér
- Marta Aymerich
- Marta Gut
- Marta Paczkowska
- Marta Tojo
- Martin Hansmann
- Martin L Ferguson
- Martin Peifer
- Mary J Goldman
- Masakazu Yamamoto
- Masaki Ueno
- Masashi Fujita
- Masashi Fukayama
- Matteo Fassan
- Matthew A Field
- Matthew A Reyna
- Matthew D Wilkerson
- Matthew Eldridge
- Matthew G Cordes
- Matthew G Soloway
- Matthew H Bailey
- Matthew H Bailey
- Matthew H Bailey
- Matthew J Anderson
- Matthew Meyerson
- Matthew R Huska
- Matthew Ringel
- Matthew W Fittall
- Matthias Bieg
- Matthias Bieg
- Matthias Schlesner
- Matthias Schlesner
- Mattia Bosio
- Maxime Tarabichi
- Maximillian G Marin
- Mayuko Furuta
- Mei Huang
- Melpomeni Kasapi
- Meyerson William U
- Mi Ni Huang
- Mia Nastic
- Michael A Hollingsworth
- Michael Birrer
- Michael C Heinold
- Michael C Heinold
- Michael C Quinn
- Michael C Wendl
- Michael C Wendl
- Michael D McLellan
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- Michael S Lawrence
- Michael S Noble
- Michele Milella
- Michele Simbolo
- Michelle Chan-Seng-Yue
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- Miguel Betancourt
- Miguel Vazquez
- Mihoko Saito-Adachi
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- Ming Tsao
- Miranda D Stobbe
- Miranda D Stobbe
- Miriam R Aure
- Miruna Balasundaram
- Mitsuhiro Komura
- Mohamed Helmy
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- Moiz S Bootwalla
- Monika Szczepanowski
- Monique Albert
- Montserrat Puiggròs
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- Morgan L Taschuk
- Moritz Gerstung
- Morten Muhlig Nielsen
- Morten Muhlig Nielsen
- Murat Iskar
- Myron Peto
- Myron Peto
- Nadia Traficante
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- Nagarajan Paramasivam
- Naoki Miyoshi
- Naomi Livni
- Naoto T Ueno
- Narong Khuntikeo
- Nasa Sinnott-Armstrong
- Nasra H Giama
- Natalie Jäger
- Natalie Jäger
- Natalie R Davidson
- Natalie S Fox
- Natalie Saini
- Nathan A Pennell
- Natsuko Hama
- Naveen Vasudev
- Nebojsa Tijanic
- Neesha C Dhani
- Neil D Merrett
- Neil E Fleshner
- Nening M Dennis
- Niall J Byrne
- Nic Jones
- Nicholas D Socci
- Nicholas J Haradhvala
- Nicholas K Hayward
- Nicholas Petrelli
- Nicholas van As
- Nick M Waddell
- Nicola D Roberts
- Nicola Grehan
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- Nicola Waddell
- Nicole Cloonan
- Nidhan K Biswas
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- Nilanjan Chatterjee
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- Nimish C Shah
- Nina Habermann
- Nina Thiessen
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- Nishant Agrawal
- Nobuyoshi Hiraoka
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- Oriol Pich
- P Andrew Futreal
- Pablo Landgraf
- Paolo Pederzoli
- Pardeep Kumar
- Paresh Vyas
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- Paul A Edwards
- Paul A Northcott
- Paul Brennan
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- Paul Flicek
- Paul M Waring
- Paul N Span
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- Paul Weinberger
- Pavana Anur
- Pavana Anur
- Payal Sipahimalani
- Paz Polak
- Pei Lin
- Pelvender Gill
- Petar Radovic
- Peter A Johansson
- Peter Clapham
- Peter F Stadler
- Peter Hersey
- Peter J Bailey
- Peter J Campbell
- Peter J Park
- Peter Lichter
- Peter Möller
- Peter O'Donnell
- Peter Staib
- Peter T Simpson
- Peter Van Loo
- Peter Vermeulen
- Peter W Laird
- Philip Awadalla
- Philip C Rosenstiel
- Phillip H Lai
- Ping Shang
- Piotr A Mieczkowski
- Prashant Bavi
- Pratiti Bandopadhayay
- Priyanka Dhingra
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- Qi Wang
- Qian Xiang
- Qiang Pan-Hammarström
- Qianyun Guo
- Qinying Xu
- Quaid D Morris
- R Houston Thompson
- R Jay Mashl
- R Jay Mashl
- Rabea Wagener
- Radhakrishnan Sabarinathan
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- Ralf Küppers
- Ralph H Hruban
- Ralph Scully
- Ramaswamy Govindan
- Rameen Beroukhim
- Randi Istrup Juul
- Raquel Rabionet
- Raunak Shrestha
- Ravikiran Vedururu
- Reanne Bowlby
- Rebecca A Dagg
- Rebecca C Fitzgerald
- Rebecca Carlsen
- Rebecca Shepherd
- Rehan Akbani
- Reiner Siebert
- Ren X Sun
- Reyka Jayasinghe
- Ricardo De Paoli-Iseppi
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- Rich Boyce
- Richard A Gibbs
- Richard A Moore
- Richard A Scolyer
- Richard F Kefford
- Richard K Wilson
- Richard Sallari
- Richard Turkington
- Rita T Lawlor
- Ritika Kundra
- Robert A Holt
- Robert C Grant
- Robert Cerfolio
- Robert E Denroche
- Robert G Bristow
- Robert L Grossman
- Robert Petryszak
- Robert S Fulton
- Robert S Fulton
- Roberto Salgado
- Roberto Salvia
- Roberto Tirabosco
- Robyn P M Saw
- Roelof Koster
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- Roland Eils
- Roland F Schwarz
- Rolf Kabbe
- Romina Royo
- Romina Royo
- Ronald Ghossein
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- Rosa Karlić
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- Roy Tarnuzzer
- Ruben M Drews
- Rui Xing
- Rui Yamaguchi
- Ruian Shi
- Russell R Broaddus
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- Sabina Signoretti
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- Salvatore Paiella
- Sam Behjati
- Samantha Bersani
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- Samirkumar B Amin
- Samuel Aparicio
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- Sancha Martin
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- Sandrine Boyault
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- Shaowu Meng
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- Shengjie Gao
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- Sietse Aukema
- Siliang Li
- Simon C Heath
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- Sonia Grimaldi
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- Susanna L Cooke
- Sushant Kumar
- Sushant Kumar
- Suyash S Shringarpure
- Syed Haider
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- Takafumi N Yamaguchi
- Takafumi N Yamaguchi
- Takanori Hasegawa
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- Takashi Yugawa
- Takuji Okusaka
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- Taobo Hu
- Taobo Hu
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- Vincent Huang
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- Vincenzo Corbo
- Vishal S Chandan
- Volker Hovestadt
- W Kimryn Rathmell
- W M Linehan
- Walker Hale
- Wan Choi
- Wanding Zhou
- Wang Liang-Bo
- Weerasinghe Amila
- Wei Jiao
- Wendl Michael C
- Wenyi Wang
- Wenyi Wang
- Wenyi Wang
- Wheeler David A
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- William C Faquin
- William Friedman
- William Howat
- William U Meyerson
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- Winghing Wong
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- Wolfgang Huber
- Wolfram Klapper
- Xavier Estivill
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- Xiao Xiao
- Xiaobo Li
- Xiaoping Su
- Xiaotong Li
- Xiaotong Yao
- Xing Hua
- Xingmin Liu
- Xinyue Li
- Xiuqing Zhang
- Xiuqing Zheng
- Xose S Puente
- Xuan Le
- Xuanping Zhang
- Xuemei Luo
- Xueqing Zou
- Yan Shi
- Yan Zhang
- Yang Wu
- Yang Yang
- Yann Joly
- Yanxun Xu
- Yao He
- Yasin Senbabaoglu
- Yassen Assenov
- Yasser Riazalhosseini
- Yasuhito Arai
- Yasushi Rino
- Yasushi Totoki
- Yeng Ang
- Yi Huang
- Yi Huang
- Yifei Men
- Yiling Lu
- Yilong Li
- Yingyan Yu
- Yiwen Chen
- Yogesh Kumar
- Yogesh Kumar
- Yoke-Eng Chiew
- Yong Hou
- Yong Zhou
- Yong-Jie Lu
- Yongzhan Nie
- Yosef E Maruvka
- Yosef E Maruvka
- Yoshiiku Kawakami
- Young Seok Ju
- Youngchoon Woo
- Youngil Koh
- Youngwook Kim
- Youyong Lu
- Yu Fan
- Yu Fan
- Yu Fan
- Yu-Jia Shiah
- Yuan Ji
- Yuan Yuan
- Yuichi Shiraishi
- Yulia Newton
- Yulia Rubanova
- Yumeng Wang
- Yupeng Cun
- Yussanne Ma
- Zachary Heins
- Zechen Chong
- Zechen Chong
- Zemin Zhang
- Zhaohong Chen
- Zhenggang Wu
- Zhenggang Wu
- Zhining Wang
- Zhongming Zhao
- Ziao Lin
- Zsofia Kote-Jarai
- Ólafur Andri Stefánsson
- Øystein Garred
- Publication venue
- Nature Communications
- Publication date
- 01/01/2020
- Field of study
Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts
Voice Rehabilitation After Transoral Laser Microsurgery of the Larynx.
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2015
- Field of study
Voice rehabilitation after transoral laser microsurgery to the larynx is challenging. We wait at least 6 months before surgical intervention. Only a few patients after total or extended cordectomy requested voice restoration. Subjective perception of voice using the Voice Handicap Index in medialization thyroplasty was significantly better. Medialization thyroplasty with elevation of the fibrous tissue from the inner surface of the thyroid cartilage is critical in achieving success. We preferred the Montgomery Thyroplasty Implant System. Transoral larynx anterior commissure stent placement after laser-assisted sectioning of anterior synechiae with application of mitomycin C is an effective procedure for anterior synechiae
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