531 research outputs found
Phase I dose-escalation and pharmacokinetic study of dasatinib in patients with advanced solid tumors
- Author
- Publication venue
- 'American Association for Cancer Research (AACR)'
- Publication date
- 29/09/2009
- Field of study
PURPOSE: To determine the maximum tolerated dose, dose-limiting toxicity (DLT), and recommended phase II dose of dasatinib in metastatic solid tumors refractory to standard therapies or for which no effective standard therapy exists.
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EXPERIMENTAL DESIGN: In this phase I, open-label, dose-escalation study, patients received 35 to 160 mg of dasatinib twice daily in 28-day cycles either every 12 hours for 5 consecutive days followed by 2 nontreatment days every week (5D2) or as continuous, twice-daily (CDD) dosing.
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RESULTS: Sixty-seven patients were treated (5D2, n = 33; CDD, n = 34). The maximum tolerated doses were 120 mg twice daily 5D2 and 70 mg twice daily CDD. DLTs with 160 mg 5D2 were recurrent grade 2 rash, grade 3 lethargy, and one patient with both grade 3 prolonged bleeding time and grade 3 hypocalcemia; DLTs with 120 mg twice daily CDD were grade 3 nausea, grade 3 fatigue, and one patient with both grade 3 rash and grade 2 proteinuria. The most frequent treatment-related toxicities across all doses were nausea, fatigue, lethargy, anorexia, proteinuria, and diarrhea, with infrequent hematologic toxicities. Pharmacokinetic data indicated rapid absorption, dose proportionality, and lack of drug accumulation. Although no objective tumor responses were seen, durable stable disease was observed in 16% of patients.<br></br>
CONCLUSION: Dasatinib was well tolerated in this population, with a safety profile similar to that observed previously in leukemia patients, although with much less hematologic toxicity. Limited, although encouraging, preliminary evidence of clinical activity was observed. Doses of 120 mg twice daily (5D2) or 70 mg twice daily (CDD) are recommended for further studies in patients with solid tumors.<br></br>
Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Athar
- Abbasy Jibran
- Abbo Olivier
- Abbott Tom
- Abbouch Meryem
- Abd El-Latif Nadia Khalid
- Abd Elkhalek Esraa
- Abd-Elmawla Manar
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A.
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulaziz Mustafa
- Abdulbagi Omar
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R.
- Aboul-Naga Mariam Saad
- Abouzaid Arwa
- Abu Qumbos Amjad
- Abu-toyour Maram
- Abubakr Marwan
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Ali
- Adam Nourhan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O.
- Ademuyiwa Adesoji O.
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adeyeye Ademola
- Adeyeye Ademola
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O.
- Adiyaman Can
- Adu-Aryee Niiarmah
- Afana Samah
- Agalianos Christos
- Agarwal Arnav
- Agarwal Arnav
- Agbedinu Kwabena
- Aglan Amro
- Aguado Suarez Nuria
- Aguilera Maria Lorena
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahlqvist Sandra
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahounou Ernest Yemalin Stephane
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi
- Ajiboye Anthony
- Akoto Elliot
- Akpenyi Onyinye
- Al Amin Shadid
- Al Attar Samaa Mahmoud
- Al Barraw Fayez Elian
- Al Bastawis Fatema
- Al Meligy Amgad
- Al Rafati Ahmad Abdel Razaq
- Al Raouf Eman Abd
- Al Saied Ghiath
- Al Subaie Norah
- Al-Bahrani Ahmed
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-faqawi Maha
- Al-farram Hadeel
- Al-khatib Ahmed
- Al-Marakby Dina
- Al-saqqa Sara
- Al-Saqqa Sara W.
- Al-Slaibi Ibrahim
- Al-taher Taher
- AlaaelDein Shahinaz
- Alada Muslimat
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Albiety Adel
- Alcca Ticona Willy
- Alejos Bermudez Ysabel Esthefany
- Alexander Philip
- Alexander Philip
- Alexandre Challine
- Alghamdi Ahmed
- Alghamdi Mohammed Saleh A.
- Alhady Khaled
- Alhammali Tariq
- Alhassan Basmah
- Alhazmi Wedyan
- Alherz Mohammad
- Ali Ahmed
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Safia
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Ali Wadah
- Alihonou Thierry
- Alis Halil
- Aliyu Halima
- Aliyu Mohammad
- Aliyu Shamsudeen
- Aljboor Khaled
- Aljiffry Murad
- Alkaaki Aroub
- Alkelani Muhammad
- Allam Meran
- Allam Yomna
- Alnaby Mohamed Hassab
- Alnusairat Aseel
- Alqahtani Saleh
- Alsaggaf Mohammed Ubaid
- Alser Osaid H.
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
- Altamimi Afnan
- Altamini Afnan
- Altarayra Marwa
- Altibi Ahmed
- Altinel Yuksel
- Altinel Yuksel
- Altwijri Abdulaziz
- Alvi Abdul Rehman
- Aly Mohammed Yahia Mohamed
- Alyacoubi Said
- Alyahya Reem
- Alzahrani Ahmed
- Aman Nowrin F.
- Amandito Radhian
- Amandito Radhian
- Ambrona-Zafra David
- Amin Hager Abdul Aziz
- Amjad Mohammadasim
- Amoah Michael
- Amoako Joachim
- Amoako Philip Taah
- Amoako-Boateng Mabel
- Amole Isaac
- Amreia Mahmoud
- Anderson Frank
- Andika Ferry Fitriya Ayu
- Andreotti Dario
- Andress Cedar
- Andriola Valeria
- Ang Yun Lin
- Angelieri Daniele
- Anis Echaieb
- Ansaloni Luca
- Ansaloni Luca
- Ansaloni Luca
- Antezana Diego
- Anthoulakis Christos
- Antoniozzi Angelo
- Anwar Nourhan
- Anyanwu Lofty-John
- Aonzo Paolo
- Appeadu-Mensah William
- Appiah Eric Kofi
- Aquilino Fabrizio
- Arafa Omar
- Arafa Sara
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- Arshad Mohammad Mohsin
- Arslan Ekin
- Arsyad Hasbi Maulana
- Arthur Tom
- Aruldas Neerav
- Asar Yomna Hosny
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- Ashour Ahmad
- Ashour Ahmad
- Ashour Khlood
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- Assal Abdelrahman
- Asturias Sabrina
- Asumah Hamza
- Ata Ahmed
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- Awadallah Salwa
- Ayandipo Omobolaji
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- Azizeldine Mohammed G.
- Azzie Georges
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- Baba Suleiman
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- Basso Stefano M. M.
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- Cox Michael
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- Cullen Fraser
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- Currow Chelise
- D'Amours Scott
- D'Souza Michelle S.
- Dabboor Majd
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- Drake Thomas M.
- Drake Thomas M.
- Drungilas Mantas
- du Plooy Flip
- Du Toit Frederick
- Duane Therese
- Duinhouwer Lucia
- Dulskas Audrius
- Ebidy Mai
- Ebidy Mai Mohamed
- Eid Mostafa Mahmoud
- El Dahab Ali Abo
- El Gendy Noran Halim
- El Halawany Mohamed
- El Jamassi Alaa
- El Kashash Ahmed
- El Sayed Islam Magdy
- El-Dien Khalid Salah
- El-Din Reham Alaa
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- El-Gizawy Esraa
- El-Sagheer Nada
- El-Sawy Aya
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- Eldeeb Ahmed Zaki
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- Elfouly Yasmin
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- Elhadad Alaa
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- Elhelbawy Mohamed Salah
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- Elhoseny Ghada
- Elhusseiny Ahmed Abd Elmoen
- Elkholy Shimaa Said
- Ellison Quinn
- Elmashala Amjad
- Elmasry Maha
- Elmihy Sohaila
- Elnagar Ahmedglal
- Elnajjar Mahmoud A.
- Elrazek Aly Abd
- Elsabbagh Nourhan
- Elsameea Ahmed Abd
- Elsawy Amira
- Elsayed Nada Ahmed Reda
- Elsemelawy Rofida
- Elshaar Mohammed
- Elshaer Mohamed
- Elshami Mohamedraed
- Elsharkawy Aya Adel
- Elsherbiney Saged
- Elsherif Fawzia Abdellatif
- Elwy Eman
- Elzahed Nada
- Emadeldin Hossam
- Emara Eman
- Emile Sameh
- Eng Calvin
- English William
- Esam Abeer
- Escalante Salas Marilia Del Carmen
- Espin-Basany Eloy
- Espinoza Fernando
- Essam A. A.
- Essam Ahmed
- Essam Mahitab
- Essoun Samuel
- Esteban Enrique
- Estee Mahnuma Mahfuz
- Etchill Eric
- Etienne Sara
- Etwire Victor
- Evajelista Cicilia Viany
- Evans David
- Evans Elizabeth
- Ezzat Eslam
- Ezzat Tarek
- Faboya Omolara
- Fahim Marwan
- Fairfield Cameron
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- Falzon Malcolm
- Farag Ahmed
- Farag Sameh
- Farahat Mahitab Morsy
- Fares Mohamed
- Farhan-Alanie Muhamed M. H.
- Farhangmehr Neda
- Farouk Sara Amr Mohamed
- Farrugia Alexia
- Farrugia Alexia
- Faruq Amreen
- Fathy Aya Mohamed
- Fatuga Adedeji
- Faturoti Olubukola
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- Feidantsis Thomas
- Fergany Alaa
- Fergusson Stuart J.
- Fergusson Stuart J.
- Fermani Claudio Gabriel
- Fernandes Cristina
- Fernandez Carmen
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- Ferousis Christoforos
- Ferrero Esther
- Filatau Aliaksandr
- Firdouse Mohammed
- Firdouse Mohammed
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- Fitzgerald J. Edward
- Fitzgerald J. Edward
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- Gad Ahmed
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- Gadelkarim Mohamed
- Gado Ammar
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- Gala Tanzeela
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- Harrison Ewen M.
- Harrison Ewen M.
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- Hassan Ihab
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- Hassanain Mazen
- Hassanein Adel B.
- Heard Rachel
- Hegazy Eman Magdy
- Helene Francois-Coridon
- Helguero-Santin Luis M.
- Hemmila Mark
- Heng Hian Ee
- Henric Nicolas
- Henry Fitjerald
- Henshall David Ewart
- Herebat Azher
- Herikstad Ragnar
- Herrera Cruz Danilo
- Herrera Matta Juan Jaime
- Herrod Philip
- Hervieux Erik
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- Hilal Karim
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- Hunter Kristina
- Husseiny Reem
- Iacono Calogero
- Iannone Immacolata
- Ibraheem Aya AbdelFatah
- Ibrahem Ahmad Aboelkassem
- Ibrahim Ahmed Mohamed
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- Ibrahim Eman Mohamed
- Ibrahim Khaled
- Ibrahim Mohamed
- Idress Tasneem
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- Ignatavicius Povilas
- Ihediwa George
- Imoro Osman
- Ingabire J. C. Allen
- Ingabire J. C. Allen
- Ioannidis Orestis
- Iqbal Muhammad Rafaih
- Ireland Philip
- Irtan Sabine
- Irwin Gareth
- Irwin Gareth
- Ishak Norzawani
- Iskandar Ferdy
- Isler Vedatcan
- Ismail Ahmed
- Ismail Lawani
- Ismail Lawani
- Ismail Lawani
- Ismail Lawani
- Ismail Mohamed
- Ismail Mohammed Kamal
- Ismail Samar Adel
- Israelsson Leif
- Ivros Nikolaos
- Iyer Dush
- Iyer Dushyant
- Jabal Mohamed Sobhi
- Jaber Sahar
- Jaffry Zahra
- Jaich Robert
- Jama Guled M.
- Jamal Luai
- Janardha K. C.
- Janik Michal
- Jankus Tomas
- Jaradat Dana
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- Javaid Mahnoor
- Jayathilake A. B.
- Jean-Francois Colombani
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- Jeffery Anna
- Jennings Vicky
- Jensen Elisabeth
- Jeo Wifanto Saditya
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- Zampitis Nikolaos
- Zani Augusto
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zeta Solis Ludwing Alexander
- Zielinski Martin
- Zilinskas Justas
- Zilinskas Justas
- Zilinskas Justas
- Zilinskiene Reda
- Ziubryte Greta
- Zohair Ahmed
- Zuber Markus
- Zuk Grzegorz
- Zulkifli Athirah
- Zumbuhl Lucius
- Publication venue
- Elsevier
- Publication date
- 01/06/2003
- Field of study
BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London
ECMO for COVID-19 patients in Europe and Israel
- Author
- Agnew Nicola
- Agnoletti Vanni
- Agus Gianluca
- Ajrhourh Lucrezia
- Akhyari Payam
- Albacete Moreno Carlos L
- Alcantara Sara
- Alessandri Francesco
- Alvarez Jorge Duerto
- Andres Nicolas Hidalgo
- Antonelli Massimo
- Aquino Verna
- Arcadipane Antonio
- Argudo Eduard
- Arnau Blasco-Lucas
- Avalli Leonello
- Baiocchi Massimo
- Balik Martin
- Ballotta Andrea
- Barker Julian
- Barrett Nicholas A
- Baumgaertel Matthias
- Bechtold Xavier
- Belliato Mirko
- Belohlavek Jan
- Benk Cristoph
- Benni Marco
- Berbel Daniel Ortiz
- Besserve Patricia
- Bettex Dominique
- Biston Patrick
- Blaha Jan
- Blanco-Schweizer Pablo
- Boado Victoria
- Boeken Udo
- Bolotin Gil
- Bombino Michela
- Bonaros Nikolaos
- Bottiroli Maurizio
- Bourgeois Marc
- Brasseur Alexandre
- Brazzi Luca
- Brenner Thorsten
- Broman Lars Mikael
- Cabanes Mari-Paz Fuset
- Camporota Luigi
- Candura Dario
- Cappai Antioco
- Carelli Simone
- Carozza Roberto
- Carton Edmund
- Casal Vanesa Gomez
- Cassina Albert Miralles
- Castro Miguel angel
- Cattaneo Sergio
- Checco Erika Dal
- Chiarini Giovanni
- Christensen Steffen
- Circelli Alessandro
- Civita Antonio
- Climent Joaquin Colomina
- Coco Valeria Lo
- Colson Pascal
- Combes Alain
- Comentale Giuseppe
- Condello Ignazio
- Conrick-Martin Ian
- Consiglio Jolanda
- Costa Maria Cristina
- Costa Ricardo Gimeno
- Courcelle Romain
- Creteur Jacques
- Czerny Martin
- Daly Kathleen
- Danzi Vinicio
- Dauwe Dieter
- Davidson Mark
- de Ayala Jose angel
- De Backer Daniel
- de Gopegui Pablo Ruiz
- de Jong Sytse
- de la Sota Perez
- de Pablo Sanchez Raul
- De Piero Maria Elena
- Debeuckelaere Gerdy
- Defraigne Jean-Olivier
- Degani Antonella
- Delnoij Thijs
- Di Nardo Matteo
- Di Nardo Matteo
- Doeble Thomas
- Donati Abele
- Dreier Esther
- Dsouki Youssef El
- Ebert Kathrin
- Fanelli Vito
- Favaro Alessandro
- Fellahi Jean Luc
- Fichte Julia
- Fina Dario
- Finney Simon
- Fiore Flavio
- Flecher Erwan
- Flemming Lucy
- Folliguet Thierry
- Fominskiy Evgeny
- Foti Giuseppe
- Fowles Jo-Anne
- Frederik Bonte
- Gallart Elisabet
- Gamberini Emiliano
- Garcia Esperanza Fernandez
- Garcia Miguel
- Garcia-de-Acilu Marina
- Gaudard Philippe
- Germay Olivier
- Ghitti Davide
- Giani Marco
- Giglioli Simone
- Gillon Stuart
- Gonzalez Anxela Vidal
- Gordillo Antonio
- Gorjup Vojka
- Grasso Salvatore
- Grazioli Lorenzo
- Grieco Domenico Luca
- Grins Edgars
- Grunenfelder Jurg
- Guinot Pierre-Gregoire
- Haenggi Matthias
- Halbe Maximilian
- Hansjoerg Jenni
- Havrin Sven
- Head Laura
- Henn Philipp
- Hennig Felix
- Herman Greet
- Higa Karina Osorio
- Hopf Hans-Bernd
- Iuliu Torje
- Jones Tim
- Juvin Charles
- Kalbhenn Johannes
- Kanetoft Mikael
- Karagiannidis Christian
- Kassif Yigal
- Kaygin Mehmet Ali
- Kersten Alexander
- Ketskalo Michail
- Kornelyuk Roman
- Kornilov Igor
- Kothleutner Florian
- Kowalewsky Mariusz
- Krapf Christoph
- Krenner Niklas
- Lagrand Wim
- Landoni Giovanni
- Latronico Nicola
- Lebreton Guillaume
- Ledot Stephane
- Lehaen Jeroen
- Leprince Pascal
- Lewis Rebecca
- Lheureux Olivier
- Liana Shestakova
- Lichtenberg Artur
- Lips Michal
- Livi Ugolino
- Livigni Sergio
- Loforte Antonio
- Lopez Marta
- Lorini Luca
- Lorusso Roberto
- Lotz Gosta
- Maas Jacinta
- Magnus Rosen
- Maier Sven
- Mair Peter
- Maisano Francesco
- Makhoul Maged
- Malfertheiner Maximilian
- Mansour Alexandre
- Mariani Silvia
- Martin-Villen Luis
- Martinez Jose Maria Nunez
- Martinez-Martinez Maria
- Martucci Gennaro
- Meani Paolo
- Meersseman Philippe
- Meyns Bart
- Milano Aldo D
- Millan Pablo
- Minin Sergei
- Miranda Dinis Reis
- Misset Benoit
- Mondino Michele
- Montalto Andrea
- Montisci Andrea
- Montrucchio Giorgia
- Moscarelli Marco
- Muellenbach Ralf
- Mueller Thomas
- Mueller Thomas
- Murgolo Francesco
- Musumeci Francesco
- Naranjo-Izurieta Jose
- Nardelli Pasquale
- Nasso Giuseppe
- Nesseler Nicolas
- Nobile Leda
- Noor Hamza
- O'Brien Serena
- Obadia Jean-Francois
- Ortiz Aaron Blandino
- Otahal Michal
- Pacini Davide
- Parasido Alessandro
- Pedersen Finn Moller
- Peperstraete Harlinde
- Piagnerelli Michael
- Piciche Marco
- Pieri Marina
- Pilato Emanuele
- Pilato Michele
- Pineton Marc
- Pinto Luis
- Pinto Luis F
- Popugaev Konstantin
- Pozzi Matteo
- Puglia Carmine
- Pugliese Francesco
- Puss Severin
- Raes Matthias
- Raffa Giuseppe
- Ramoni Enrico
- Ranucci Marco
- Redfors Bengt
- Reina Gianfranco
- Reyher Christian
- Ricart Pilar
- Richard Jean Christophe
- Riera Jordi
- Riera Jordi
- Rociola Ruggero
- Rodrigus Inez
- Roeleveld Peter
- Rolfes Caroline
- Rona Roberto
- Russo Claudio Francesco
- Russo Emanuele
- Saeed Diyar
- Saiydoun Gabriel
- Sales Gabriele
- Salvador Loris
- Samalavicius Robertas
- Sanchez-Salado Jose Carlos
- Sandoval Elena
- Sandrelli Luca
- Santa Teresa Patricia
- Sargin Murat
- Scandroglio Anna Mara
- Schafer Simone
- Schellongowski Peter
- Schibilsky David
- Schmidt Matthieu
- Schmitto Jan D
- Scholten Erik
- Scott Ian
- Scott Ian
- Shelukhin Daniil
- Simonetti Umberto
- Skopets Alexander
- Smith Jonathan
- Soerensen Gro
- Sonntagbauer Michael
- Soufleris Dimitros
- Speziale Giuseppe
- Sponga Sandro
- Staudacher Dawid L
- Stockman Bernard
- Swol Justyna
- Taccone Fabio Silvio
- Thiele Holger
- Thielmann Matthias
- Timmermans Philippe
- Tosi Antonella
- Tsarenko Sergey
- Turchaninov Alexandr
- Urbino Rosario
- van Belle-van Haren Nicole
- van den Berg MJ van Gijlswijk
- van der Heijden JJ
- van der Horst Iwan
- van der Linden Marcel
- Vandenbriele Christophe
- Vandeweghe Dimitri
- Vandewiele Korneel
- Veganzones Javier
- Velia Antonini M
- Velia Antonini M
- Vercaemst Leen
- Vercaemst Leen
- Verhoye Jean-Philippe
- Vlasselaers Dirk
- Watson Pia
- Weber Alberto
- Witters Ine
- Worthy Jennifer
- Yonis Hodane
- Zacharowski Kai
- Zangrillo Alberto
- Zanin Anita
- Zarka Jonathan
- Zenklusen Urs
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2021
- Field of study
Since March 15th, 2020, 177 centres from Europe and Israel have joined the study, routinely reporting on the ECMO support they provide to COVID-19 patients. The mean annual number of cases treated with ECMO in the participating centres before the pandemic (2019) was 55. The number of COVID-19 patients has increased rapidly each week reaching 1531 treated patients as of September 14th. The greatest number of cases has been reported from France (n = 385), UK (n = 193), Germany (n = 176), Spain (n = 166), and Italy (n = 136) .The mean age of treated patients was 52.6 years (range 16–80), 79% were male. The ECMO configuration used was VV in 91% of cases, VA in 5% and other in 4%. The mean PaO2 before ECMO implantation was 65 mmHg. The mean duration of ECMO support thus far has been 18 days and the mean ICU length of stay of these patients was 33 days. As of the 14th September, overall 841 patients have been weaned from ECMO
support, 601 died during ECMO support, 71 died after withdrawal of ECMO, 79 are still receiving ECMO support and for 10 patients status n.a. . Our preliminary data suggest that patients placed
on ECMO with severe refractory respiratory or cardiac failure secondary to COVID-19 have a reasonable (55%) chance of survival. Further extensive data analysis is expected to provide invaluable information on the demographics, severity of illness, indications and different ECMO management strategies in these patients
Global disparities in surgeons’ workloads, academic engagement and rest periods: the on-calL shIft fOr geNEral SurgeonS (LIONESS) study
- Author
- Abdelkhalek Mohamed
- Abellán Antonio Melero
- Abelló David
- Abu-Arish Hamdoon
- Acevedo Ana Karen Radilla
- Adamina Michel
- Adamovich Dmitry Mikhailovich
- Addeo Pietro
- Adewunmi Olayinka Lukman
- Aeschbacher Pauline
- Afolabi Akinwale Ibrahim
- Agastra Ervis
- Agresta Ferdinando
- Aguilar Juan Carlos Cardozo
- Ahmed Bensaad
- Ahmed Nauman
- Aimal Aimal Khan
- Aiolfi Alberto
- Akay Omer
- al-Najami Issam
- Al-Shehari Mohammed
- Alconchel Felipe
- Alesina Pier Francesco
- Alhazmi Ahmad
- Ali Mahmoud Ibrahim
- Aliyev Vusal
- Alonso Patricia
- Aloun Ali
- Altinel Yuksel
- Altomare Michele
- Alvarez-Gallego Mario
- Ammendola Michele
- Ammerata Giorgio
- Anania Marco
- Anas Abdelhmed
- Andreuccetti Jacopo
- Andriola Valeria
- Andriola Valeria
- Anelli Ferdinando M.
- Anestiadou Elissavet
- Angrisani Marco
- Antonacci Nicola
- Antonacci Nicola
- Antonelli Amedeo
- Antropoli Carmine
- Aparicio Antonio Carlos Maya
- Apostolou Konstantinos
- Arcudi Claudio
- Aregawi Alazar Berhe
- Argenio Giulio
- Ascari Francesca
- Asfaw Fitsum Terefe
- Athar Rahmatullah
- Atici Semra Demirli
- Au Stephanie
- Augustin Goran
- Avella Pasquale
- Avellaneda Nicolas
- Awad Ahmed K.
- Awad Selmy S.
- Awad Selmy S.
- Ayalew Alem Mekete
- Aytac Erman
- Aytac Erman
- Azevedo José
- Baba Arshad Ahmed
- Bacchiocchi Giulia
- Bagaglini Giulia
- Bagaria Dinesh
- Baili Efstratia
- Bains Lovenish
- Baiocchi Gian Luca
- Bala Miklosh
- Balaphas Alexandre
- Balassone Valerio
- Baldi Caterina
- Baldini Edoardo
- Balla Andrea
- Ballester Cristina
- Bandaru Kalyan Vijay Kumar
- Bandyopadhyay Samik K.
- Bannone Elisa
- Barba Leonardo A.
- Barberis Andrea
- Barone Mirko
- Barranquero Alberto G.
- Barugola Giuliano
- Barzola Ernesto J.
- Batıkan Oğuzkağan
- Bavikatte Akshay Prasannakumar
- Bayileyegn Nebiyou Simegnew
- Bedros Nicole Mary
- Beisani Marc
- Bejiga Gosa Hundie
- Bekana Bekana L.
- Belay Tatek
- Belia Francesco
- Belkacem Acidi
- Bellanova Giovanni
- Bellato Vittoria
- Bellido-luque Juan
- Bellini Maria Irene
- Bellver Pedro Palazón
- Benzoni Enrico
- Benzoni Ilaria
- Bergna Alessandro
- Bhat Pawan Singh
- Bhattacharya Kaushik
- Bhattacharya Neela
- Bhatti Hamza Waqar
- Bianchi Valentina
- Bianco Giuseppe
- Biloslavo Alan
- Biniam Ewnte
- Blanco-Antona Francisco
- Bocchino Antonio
- Bointas Georgios
- Bollino Ruggero
- Bonavina Luigi
- Bondurri Andrea
- Bonilla Fernando
- Bonito Alba Correa
- Bono Dario
- Borges Nuno
- Botelho Pedro
- Bottari Andrea
- Bottcher Sofia Maria Jaume
- Bourguiba Mohamed Aboulkacem
- Bourmpouteli Eirini
- Bouzid Chafik
- Braccio Bartolomeo
- Brady Richard R. W.
- Braholli Eriol
- Brasset Camille
- Brillantino Antonio
- Brillantino Antonio
- Briones Cristhian Gonzalo Aspiazu
- Brisinda Giuseppe
- Brito Ismael
- Brookes Charlotte Elisabeth
- Brucchi Francesco
- Bulte Joris P.
- Buonomo Oreste Claudio
- Butler Rebecca Jayne
- Cacciaguerra Andrea Benedetti
- Caldeira Beatriz
- Calini Giacomo
- Calu Valentin
- Calussi Marco
- Calussi Marco
- Cammarat Roberto
- Cammarata Roberto
- Campagnaro Tommaso
- Campanelli Michela
- Campisi Andrea
- Campus Federica
- Candilio Giuseppe
- Cannavo Maurizio
- Cannistra Marco
- Cannistra Marco
- Cano-Valderrama Oscar
- Canonico Giuseppe
- Cantarino Frederico
- Capitano Sante
- Capolupo Gabriella Teresa
- Cappuccio Micaela
- Capuano Marianna
- Capuano Marianna
- Caputo Damiano
- Carannante Filippo
- Carbone Ludovico
- Cardinali Luca
- Carneros Virginia Jiménez
- Carrabetta Salvatore
- Caruso Riccardo
- Carvas João M.
- Carvas João M. B.
- Casagranda Biagio
- Casas Maria Agustina
- Cascales-Sanchez Pedro
- Cassese Gianluca
- Castaldi Antonio
- Castaldi Antonio
- Castellano Javier Rivera
- Castro Ernest
- Castro Maria J.
- CC Tommaso
- Celentano Valerio
- Celotti Andrea
- Cerdán-Santacruz Carlos
- Cereda Marco Angelo
- Ceresoli Marco
- Cero Mariagiulia Dal
- Cestaro Giovanni
- Cestino Luca
- Chai Feng Yih
- Chalkoo Mushtaq A.
- Charalabopoulos Alexandros
- Charalabopoulos Alexandros
- Charitaki Evgenia
- Chessa Antonella
- Chessa Antonella
- Chevallay Mickael
- Chia Chi Fung
- Chillarge Gauri
- Chimenti Federica
- Chitul Andrei
- Chiu Jennifer H. F.
- Chooklin Serge
- Choudhry Asad
- Chouliaras Christos
- Chowdhury Ashim
- Christodoulou Prokopis
- Chrysikos Michael
- Chukwu Isaac Sunday
- Cianci Pasquale
- Ciarleglio Francesco A.
- Cicerchia Pierfranco Maria
- Ciesielski Wojciech J.
- Cigognini Maria
- Cillara Nicola
- Cioffi Stefano Piero Bernardo
- Ciro Mauricio Pedraza
- Clementi Marco
- Clocchiatti Lucrezia
- Colak Elif
- Colás-Ruiz Enrique
- Coletta Diego
- Colombari Renan C.
- Colombo Francesco
- Colucci Gianluca
- Conte Luigi E.
- Conti Luigi
- Coppola Alessandro
- Corallino Diletta
- Corronca Federico
- Corrons Laia Codina
- Corvasce Arianna
- Costantini Giulia
- Costanzo Antonio
- Costea Radu V.
- Cotsoglou Christian
- Cozza Valerio
- Creavin Ben
- Cremona Simone
- Cricrì Michele
- Crosbie Gonzalo Gabriel
- Cuccomarino Salvatore
- Cuk Vladica
- Cunha Miguel
- Curcio Silvia
- Curro Giuseppe
- Dajti Irida
- Daniel Clerc
- Dardanov Dragomir
- Davey Matthew G.
- Davies Justin
- Davis Daniel G.
- De Andrés-Asenjo Beatriz
- De Campos Tercio
- De Carlis Riccardo
- de las Casas Sara Gortázar
- De Luca Alessandro
- De Luca Raffaele
- De Lucia Chiara
- De Nobili Giovanni
- de Oliveira Gabriel Paiva
- De Padua Cristina
- De Rosa Michele
- de Sa Tiago Correia
- de Santos Iglesias Francisco Juan
- De Simone Belinda
- de Vries Hilbert S.
- Debela Bizuneh Sime
- Debena Dawit Gebregiorgis
- Deerenberg Eva B.
- Del Monte Simone Rossi
- del Olmo Juan Carlos Martín
- Delaune Vaihere
- Delgado Ander Timoteo
- Delis Spiros
- Delogu Daniele
- Delvecchio Antonella
- Demir Anıl
- Devriendt Stefanie
- Di Bella Annamaria
- Di Carlo Isidoro
- Di Filippo Giacomo
- Di Franco Gregorio
- Di Lascio Pierpaolo
- Di Marco Federica
- Di Marco Federica
- Di Marco Federica
- Di Martino Marcello
- Di Martino Marcello
- Di Meo Giovanna
- di Mola Fabio F.
- Di Santo Albini Andrea G.
- Di Saverio Salomone
- Di Saverio Salomone
- Di Venere Beatrice
- Diaz-Elizondo Jose Antonio
- Diaz-Elizondo Jose Antonio
- Digne-Malcolm Holly Jane
- Dimitrov Evgeni
- Dinagde Tesfaye Aga
- Díaz Carlos JGómez
- Don Cristine Brooke Pathirannehalage
- Dorovinis Panagiotis
- Douka Eleftheria
- Drogouti Maria
- Dudi-Venkata Nagendra N.
- Dulskas Audrius
- Dulskas Audrius
- Dziakova Jana
- D’Acapito Fabrizio
- D’Ambrosio Marco
- D’Ambrosio Marco
- D’Ugo Stefano
- Efetov Sergey
- Efetov Sergey
- Elfeki Hossam
- Elghadban Hosam Mohamed
- Emile Sameh
- Ercolani Giorgio
- Erdoğan Emre
- Ermias Nebiyou
- Escalante Karol S.
- Espino Eduardo Morales
- Esposito Francesco
- Esposito Giuseppe
- Estaire-Gómez Mercedes
- Fabbri Nicolò
- Fabbrizio Tiziana
- Farazi-Chongouki Christos
- Faro Carmelo Lo
- Faro Carmelo Lo
- Farolfi Tommaso
- Farooqui Marryam Riaz
- Farrarons Sara Sentí
- Farré Silvia Pérez
- Farrukh Maira
- Fazio Federico
- Feituri Nura
- Feleke Tsega Terefe
- Felsenreich Daniel M.
- Fernandez Carmen Cagigas
- Fernández Fernández June
- Fernicola Agostino
- Ferrara Francesco
- Ferrari Davide
- Ferrario Luca
- Ferreira Rodrigo Vaz
- Ferretti Carlotta
- Ferronetti Antonio
- Festa Federico
- Fichera Alessandro
- Fiore Felicia
- Fleming Andrew Martin
- Fleres Francesco
- Florio Gaetano
- Folliero Cristina
- Fonseca Vinicius Cordeiro
- Forcignanò Edoardo
- Foreman Michaael L.
- Formisano Giampaolo
- Fortuna Laura
- Franchi Eloisa
- Francis Fayez Maged
- Francone Elisa
- Francone Elisa
- Fransvea Pietro
- Frazzetta Giuseppe
- Freixa Celia Caula
- Frontali Alice
- Frountzas Maximos
- Funk Geoffrey A.
- Fuschillo Giacomo
- Gachabayov Mahir
- Galeev Shamil I.
- Galiffa Giampaolo
- Gall Malina ECaraiman
- Gallardo Cristian
- Gallo Gaetano
- Garoufalia Zoe
- Garzali Ibrahim Umar
- Gauci Chahaya M.
- Gazia Carlo
- Gerogiannis Ioannis
- Gervasi Maria Clelia
- Gessa Emanuela
- Ghannam Wagih
- Gherardi Dario
- Ghignone Federico
- Gialamas Eleftherios
- Giambusso Mauro
- Gica Nicolae
- Giordano Alessio
- Giordano Marco
- Giovine Gennaro
- Giuffrida Maria Carmela
- Giuffrida Mario
- Giuliani Antonio
- Giuliani Giuseppe
- Glasbey James
- Gomes Carlos Augusto
- Gonfa Kebebe Bekele
- Gonsaga Ricardo Alessandro Teixeira
- Gonzalez Ana
- González Lluis García
- González Tomas Elosua
- Gourgiotis Stavros
- Gómez Marta Jiménez
- Gómez Marta Jiménez
- Göktepe Berk
- Grama Florin A.
- Granata Roberta
- Gravante Gianpiero
- Greco Antonio
- Grimaldi Luciano
- Grossi Ugo
- Guerci Claudio
- Guerrero María Alejandra
- Guevara Jenny
- Guitart Marc Pérez
- Gulcu Baris
- Guler Mert
- Gulmez Mehmet
- Gunay Emre
- Gupta Amit
- Gupta Ashish
- Gussago Stefano
- Gülcü Barış
- Güngör Mert
- Hailemariam Dagnachew H.
- Halder Subhadip
- Hale Lyman Lansing
- Harvitkar Rafique Umer
- Hassen Khalid Arebo
- Hernandez-Garcia Miguel
- Hernández Edgard Efrén Lozada
- Horesh Nir
- Iacobone Maurizio
- Iannone Immacolata
- Ibáñez Noelia
- Ibrahim Aini Fahriza
- Idiz Ufuk Oguz
- Ielpo Benedetto
- Ielpo Benedetto
- Imana Ruhama Yoseph
- Inama Marco
- Ingallinella Sara
- Ingallinella Sara
- Ioannidis Argyrios
- Ioannidis Orestis
- Iodice Alessandra
- Ioia Giovanna
- Iordache-Petrescu Madalina Ionela
- Iossa Angelo
- Iqbal Muhammad Rafaih
- Iranzo Marina Alarcón
- Isik Arda
- Izzo Giuliano
- Jamiri Al-Radjid
- Jansson Hannes
- Johnson Benjamin E.
- Jordão Daniel Filipe Martins
- Juloski Jovan
- Junior Marcelo A. F. Ribeiro
- Kampouroglou Georgios
- Kapsampelis Panagiotis
- Kara Yasin
- Karamarkovic Aleksandar
- Karamarkovic Aleksandar
- Karamarkovic Aleksandar
- Kaur Mandeep
- Kchaou Ali
- Kebede Kirubel Abebe
- Keci Laura
- Keller Deborah S.
- Kelly Michael E.
- Khan Huma Ahmed
- Khan Jan Sher
- Khan Mansoor
- Khobragade Krunal H.
- Kiros Samuel
- Klib Mohamad
- Klimczak Tomasz Jerzy
- Knickerbocker Chase Barrett
- Kobe Yoshiro
- Koëter Tijmen
- Koh Peng Soon
- Komaei Iman
- Koneti Akshadhar J.
- Konstantoudakis Georgios
- Koppel Darren
- Korkoman Mohammed J.
- Kosir Jurij A.
- Kovacevic Bojan
- Krsicka Petr
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- Kucukarslan Rabia
- Kykalos Stylianos
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- Neves Fernanda V. S.
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- null null
- Nunziante Marco
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- Rico Douglas
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- Scotti Mauro Alessandro
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- Sibaja-Matamoros Dauber A.
- Sica Giuseppe S.
- Sidiropoulou Zacharoula
- Silvestro Roberto
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- Slesser Alistair A. P.
- Sliwinski Svenja Christin
- Smerieri Elia
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- Soldini Gabriele
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- Stringfield Sarah Beth
- Stubbs Benjamin M.
- Subramaniam Ravichandran
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- Syn Nicholas L.
- Synekidou Eirini
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- Tan Jessica J.
- Tan Jih Huei
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- Travers Lawrence Albert Salter
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- Tryliskyy Yegor
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- Tur-Martinez Jaume
- Tur-Martinez Jaume
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- Uggeri Fabio
- Uzunoglu Mustafa Yener
- Uzzau Alessandro
- Uzzau Alessandro
- Vailas Michail
- Vailas Michail
- Valadez Michel Hernandez
- Valdivieso Xavier HGarcía
- Valinoti Agustín
- Van Doorn Berend
- van Ramshorst Gabrielle
- Vanerio Patricio
- Vannelli Alberto
- Vanni Gianluca
- Vanni Gianluca
- Varela Cristopher
- Varela Cristopher L.
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- Veroux Massimiliano
- Vescio Francesca
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- Vinci Danilo
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- Walędziak Maciej
- Wani Ajaz
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- Wani Rauf
- Wassie Chekol
- Wilkins Alex
- Wyroslak-Najs Justyna
- Yallew Gebeyaw Mengist
- Yang Wah
- Yildirim Ali Cihat
- Yildiz Ishak
- Yiu Andrew
- Yiu Andrew
- Younis Muhammad Umar
- Yusoff Ahmad Ramzi
- Zacharis Georgios
- Zafra David Ambrona
- Zaghloul Tarek M.
- Zambon Martina
- Zanus Giacomo
- Zarnescu Narcis Octavian
- Zeb Muhammad
- Zena Alemayehu Shanko
- Zerbo Domenico
- Zuchini Andrés Mendoza
- Zullo Alessia
- Publication venue
- Publication date
- 29/04/2024
- Field of study
: The workload of general surgeons is multifaceted, encompassing not only surgical procedures but also a myriad of other responsibilities. From April to May 2023, we conducted a CHERRIES-compliant internet-based survey analyzing clinical practice, academic engagement, and post-on-call rest. The questionnaire featured six sections with 35 questions. Statistical analysis used Chi-square tests, ANOVA, and logistic regression (SPSS® v. 28). The survey received a total of 1.046 responses (65.4%). Over 78.0% of responders came from Europe, 65.1% came from a general surgery unit; 92.8% of European and 87.5% of North American respondents were involved in research, compared to 71.7% in Africa. Europe led in publishing research studies (6.6 ± 8.6 yearly). Teaching involvement was high in North America (100%) and Africa (91.7%). Surgeons reported an average of 6.7 ± 4.9 on-call shifts per month, with European and North American surgeons experiencing 6.5 ± 4.9 and 7.8 ± 4.1 on-calls monthly, respectively. African surgeons had the highest on-call frequency (8.7 ± 6.1). Post-on-call, only 35.1% of respondents received a day off. Europeans were most likely (40%) to have a day off, while African surgeons were least likely (6.7%). On the adjusted multivariable analysis HDI (Human Development Index) (aOR 1.993) hospital capacity > 400 beds (aOR 2.423), working in a specialty surgery unit (aOR 2.087), and making the on-call in-house (aOR 5.446), significantly predicted the likelihood of having a day off after an on-call shift. Our study revealed critical insights into the disparities in workload, access to research, and professional opportunities for surgeons across different continents, underscored by the HDI
Analysis of shared heritability in common disorders of the brain
- Author
- Adams Hieab H.H.
- Air Tracy
- Al-Chalabi Ammar
- Alda Martin
- Alegret Montserrat
- Alfredsson Lars
- Amouyel Philippe
- Andlauer Till F.M.
- Andreassen Ole A.
- Anjorin Adebayo
- Anney Richard
- Anttila Verneri
- Arias Vasquez Alejandro
- Arking Dan
- Arnold Paul
- Arranz Maria Jesús
- Artto Ville
- Aschauer Harald
- Attia John
- Avbersek Andreja
- Bacchelli Elena
- Bailey Anthony
- Baker Jessica H.
- Bal Vanessa
- Banaschewski Tobias
- Barnes Lisa L.
- Barr Cathy L.
- Battaglia Agatino
- Battey Thomas
- Bau Claiton H.D.
- Bauer Michael
- Baum Larry
- Baune Bernhard T.
- Bayer Anthony
- Beach Thomas G.
- Becker Felicitas
- Bedoya-Berrio Gabriel
- Beekman Aartjan TF
- Beiser Alexa
- Belin Andrea C.
- Bergen Andrew W.
- Bergen Sarah E
- Berkovic Samuel
- Berr Claudine
- Betancur Catalina
- Bevan Steve
- Bienvenu O. Joseph
- Bis Joshua C
- Blackwood Douglas
- Boada Mercè
- Boland Anne
- Bolton Patrick
- Boncoraglio Giorgio
- Boomsma Dorret
- Boraska Perica Vesna
- Borck Guntram
- Bradfield Jonathan
- Bramon Elvira
- Bras Jose
- Breen Gerome
- Brentani Helena
- Buccola Nancy
- Buitelaar Jan K.
- Bulik Cynthia M.
- Bulik-Sullivan Brendan
- Buono Russell
- Buring Julie E.
- Burton Christie
- Børglum Anders D.
- Cahn Wiepke
- Cairns Murray
- Camarena Beatriz
- Cantor Rita
- Cappi Carolina
- Casas Miguel
- Catarino Claudia B.
- Cath Danielle
- Cavallini Maria
- Celestino-Soper Patrícia
- Chasman Daniel I.
- Chen Wei-Min
- Cheng Wei
- Chong Siow A.
- Chouraki Vincent
- Churchhouse Claire
- Cichon Sven
- Clementi Maurizio
- Cloninger Robert
- Cohen David
- Cohen-Woods Sarah
- Cook Edwin
- Cormand Bru
- Corvin Aiden
- Cossette Patrick
- Cotsapas Chris
- Craddock Nick
- Crespo-Facorro Benedicto
- Crosbie Jennifer
- Crowley James
- Cruceanu Cristiana
- Cruchaga Carlos
- Cuenca-Leon Ester
- Curtis David
- Cusi Daniele
- Czerski Piotr M.
- Dalsgaard Soeren
- Daly Mark
- Danner Unna N.
- Darrow Sabrina
- Davidson Michael
- Davis Oliver S. P.
- Dawson Geraldine
- de Geus Eco
- De Jager Philip L.
- De Jonghe Peter
- De Rubeis Silvia
- De-Luca Daniel Moreno-
- Degenhardt Franziska
- Deleuze Jean-François
- DeLisi Lynn
- Delorme Richard
- Demirci F. Yesim
- Dempfle Astrid
- Denys Damiaan
- Depienne Christel
- Depondt Chantal
- Derks Eske M.
- Dichgans Martin
- Dick Danielle M.
- Dietrich Andrea
- Dinan Timothy
- Dlugos Dennis
- Docampo Elisa
- Donohoe Gary
- Doyle Alysa E.
- Drapeau Elodie
- Duan Jubao
- Duncan Laramie
- Dunn Erin
- Duque Frederico
- Duron Emmanuelle
- Edenberg Howard J.
- Ehrlich Stefan
- Elia Josephine
- Eriksson Nicholas
- Escott-Price Valentina
- Espeseth Thomas
- Falcone Guido J.
- Faraone Stephen V.
- Farh Kai-How
- Farrer Lindsay A.
- Fernandez Thomas
- Ferrari Michel D.
- Ferraro Thomas N.
- Ferrier I. Nicol
- Figee Martijn
- Finucane Hilary K.
- Fischer Sascha B.
- Forstner Andreas J.
- Forzan Monica
- Fox Nick C.
- Franke Barbara
- Freilinger Tobias
- Freimer Nelson
- Freitag Christine
- French Jacqueline
- Fullerton Janice M.
- Furlotte Nicholas
- Gasser Thomas
- Gejman Pablo V.
- Gerber Gloria
- Gershon Elliot S.
- Geschwind Daniel H.
- Gibbs Raphael
- Goate Alison M.
- Goes Fernando S.
- Gonidakis Fragiskos
- Gordon Scott D.
- Gormley Padhraig
- Grabe Hans-Jorgen
- Grados Marco
- Gratacos Monica
- Green Andrew
- Greenberg Erica
- Grenier-Boley Benjamin
- Grevet Eugenio H.
- Grigoroiu-Serbanescu Maria
- Grove Jakob
- Guerreiro Rita
- Guzman-Parra José
- Göbel Hartmut
- Haan Lieuwe
- Haavik Jan
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- Halmi Katherine A.
- Hampel Harald
- Hanna Gregory L.
- Hannequin Didier
- Hansen Thomas
- Harold Denise
- Hartmann Andreas
- Hauser Joanna
- Head Elizabeth
- Heinzen Erin L.
- Helder Sietske G.
- Henskens Frans
- Herms Stefan
- Herpertz-Dahlmann Beate
- Hervas Amaia
- Heutink Peter
- Hickie Ian
- Hirschtritt Matthew E.
- Hjalgrim Helle
- Hoekstra Pieter J.
- Hoffmann Per
- Holliday Elizabeth
- Holmans Peter
- Homuth Georg
- Hottenga Jouke-Jan
- Hougaard David
- Hrafnsdottir Maria
- Huang Alden
- Huang Hailiang
- Huang Jie
- Huckins Laura M.
- Hudson James I.
- Huentelman Matthew J.
- Hulette Christine M.
- Huyser Chaim
- Hyman Bradley T.
- Hämäläinen Eija
- Illmann Cornelia
- Jamain Stéphane
- Jamnadas-Khoda Jennifer
- Jansen Rick
- Jenike Michael
- Jicha Gregory A.
- Johansson Stefan
- Jones Ian R.
- Julià Antonio
- Kamatani Yoichiro
- Kamboh M. Ilyas
- Kaprio Jaakko
- Karachanak-Yankova Sena
- Karwautz Andreas
- Kaunisto Mari
- Kauwe John S.K.
- Kaye Jeffrey A.
- Kaye Walter
- Kendler Kenneth S.
- Keski-Rahkonen Anna
- Khrunin Andrey
- Klauck Sabine M.
- Klovins Janis
- Knowles James A.
- Koeleman Bobby
- Konkashbaev Anuar
- Kornhuber Johannes
- Kourkoulis Christina
- Kubisch Christian
- Kukull Walter A.
- Kuntsi Jonna
- Kunz Wolfram S.
- Kuperman Samuel
- Kurki Mitja I.
- Kurth Tobias
- Kučinskas Vaidutis
- Kälviäinen Reetta
- Langley Kate
- Lanzagorta Nuria
- Larson Eric B.
- Lawlor Brian
- Leber Markus
- Leboyer Marion
- Lee Chee Keong Jimmy
- Lee Phil H.
- Lehtimäki Terho
- Lerche Holger
- Lesch Klaus-Peter
- Letenneur Luc
- Leu Costin
- Leventhal Bennett
- Leverenz James B.
- Levey Allan I.
- Levitt Pat
- Lewis Cathryn M.
- Li Qingqin S.
- Lieberman Andrew P.
- Ligthart Lannie
- Limborska Svetlana
- Lindhout Dick
- Lissowska Jolanta
- Lo Warren
- Lochner Christine
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- Loughland Carmel
- Lowenstein Daniel
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- Lönnqvist Jouko
- Maaser Anna
- Macaya Alfons
- Macciardi Fabio
- MacIntyre Donald J.
- Madruga-Garrido Marcos
- Maestrini Elena
- Magalhaes Tiago
- Maher Brion
- Maj Mario
- Malaty Irene A.
- Malik Rainer
- Mane Shrikant
- Mannik Katrin
- Maras Athanasios
- Markus Hugh
- Marson Anthony
- Martin Nicholas G.
- Martinez Maria
- Mathews Carol A.
- Mattheisen Manuel
- Matthews Keith
- Mattingsdal Morten
- Mayoral Fermin
- McCormack Mark
- McDonald Colm
- McGough James J.
- McGrath Lauren
- McIntosh Andrew
- McLaughlin Nicole
- McQuillin Andrew
- Mead Simon
- Medland Sarah E.
- Mehta Divya
- Melle Ingrid
- Metspalu Andres
- Middeldorp Christel M.
- Miguel Eurípedes C.
- Mir Pablo
- Mitchell Braxton
- Mitchell James
- Mitchell Philip B.
- Mok Kin Y.
- Molloy Anne
- Molly Nikolas
- Monteleone Palmiero
- Montgomery Grant W.
- Morgan Kevin
- Morris Derek
- Morris Huw R.
- Muller-Myhsok Bertram
- Murphy Kieran C.
- Murray Robin
- Møller Rikke S.
- Mühleisen Thomas W.
- Nauck Matthias
- Neale Benjamin M.
- Nenadic Igor
- Nestadt Gerald
- Nestadt Paul S.
- Ng Ping-Wing
- Nicolini Humberto
- Nyholt Dale R.
- Nöthen Markus M.
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- Oh Sang-Yun
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- Olesen Jes
- Oliver Karen
- Ophoff Roel
- Owen Michael J.
- O’Toole Julie K.
- Padyukov Leonid
- Pakstis Andrew
- Palmason Haukur
- Palotie Aarno
- Palta Priit
- Pankratz Vernon S.
- Pantelis Christos
- Papezova Hana
- Parr Jeremy
- Paschou Peristera
- Passmore Peter
- Pato Carlos
- Pato Michele
- Patsopoulos Nikolaos A.
- Penninx Brenda
- Pera Joana
- Pergadia Michele
- Petryshen Tracey
- Piacentini John
- Pinto Dalila
- Pittenger Christopher
- Plessen Kerstin
- Poon Wayne W.
- Porteous David
- Posthuma Danielle
- Potash James B.
- Pozo-Rosich Patricia
- Price Alkes
- Privitera Michael
- Proitsi Petra
- Pulit Sara
- Quested Digby
- Quinn Joseph F.
- Rabionet Raquel
- Radtke Rodney
- Raevuori Anu
- Raffeld Miriam
- Ramensky Vasily
- Ramos Eliana M.
- Ramos-Quiroga Josep Antoni
- Ran Caroline
- Ransmayr Gerhard
- Regan Regina
- Reichborn-Kjennerud Ted
- Reichenberg Abraham
- Reif Andreas
- Reinbold Céline S.
- Reitz Christiane
- Reus Victor
- Ribasés Marta
- Rice John
- Rice Kenneth
- Richter Margaret A.
- Riddle Mark A.
- Riedel-Heller Steffi
- Riemenschneider Matthias
- Rietschel Marcella
- Ripatti Samuli
- Ripke Stephan
- Rivera Margarita
- Rivero Olga
- Robertson Mary M.
- Robinson Elise
- Roessner Veit
- Rogaeva Ekaterina
- Rogé Bernadette
- Romanos Marcel
- Rosand Jonathan
- Rossor Martin
- Rosário Maria
- Rothenberger Aribert
- Rothwell Peter
- Rotter Jerome I
- Rouleau Guy A.
- Roussos Panos
- Rubinsztein David C.
- Ruiz Agustin
- Ruppert Ann-Kathrin
- Russo Giancarlo
- Rybakowski Filip
- Ryten Mina
- Salomaa Veikko
- Samuels Jack F.
- Sander Thomas
- Sanders Alan R.
- Sandin Sven
- Sandor Cynthia
- Sandor Paul
- Santangelo Susan
- Saykin Andrew J.
- Schachar Russell
- Schachter Steven
- Schall Ulrich
- Schalling Martin
- Schankin Christoph
- Scharf Jeremiah
- Scheffer Ingrid
- Scherer Stephen W.
- Schneider Lon S.
- Schoch Susanne
- Schoevers Robert A.
- Schofield Peter R.
- Schosser Alexandra
- Schott Jonathan M.
- Schreiber Stefan
- Schulze Thomas G.
- Schumacher Johannes
- Schwab Sibylle G.
- Schürks Markus
- Scott Rodney
- Seshadri Sudha
- Sharma Manu
- Sharma Pankaj
- Silliman Scott
- Sim Kang
- Sinnamon Grant
- Sisodiya Sanjay M.
- Sklar Pamela
- Smit Johannes H.
- Smith Amanda G.
- Smith Philip
- Smoller Jordan W.
- So Hon-Cheong
- Sonnen Joshua A.
- Sperling Michael
- St George-Hyslop Peter
- Stahl Eli
- Steen Vidar M.
- Stein Dan J.
- Stern Robert A.
- Streit Fabian
- Striano Pasquale
- Strober Michael
- Strohmaier Jana
- Stroink Hans
- Stögmann Elisabeth
- Subramaniam Mythily
- Sudlow Cathie
- Sullivan Patrick
- Surges Rainer
- Szatkiewicz Jin Peng
- Sánchez-Mora Cristina
- Terwindt Gisela M.
- The Brainstorm Consortium
- Thijs Vincent
- Thomas G. Neil
- Thompson Robert C.
- Thornton Laura M.
- Toncheva Draga
- Tortorella Alfonso
- Trace Sara E.
- Tsetsos Fotis
- Tsolaki Magda
- Turecki Gustavo
- Turley Patrick
- Tziouvas Konstantinos
- Valencia-Duarte Ana
- Van Deerlin Vivianna M.
- van den Maagdenberg Arn M.J.M.
- van der Lee Sven J.
- van Elburg Annemarie A.
- Van Eldik Linda J.
- Van Nieuwerburgh Filip
- van Os Jim
- Vardarajan Badri N.
- Vepsäläinen Salli
- Vicente Astrid
- Viktorin Alexander
- Visscher Frank
- Vorstman Jacob
- Waddington John
- Wagner Gudrun
- Waldman Irwin
- Walters James
- Walters Raymond K.
- Wassink Thomas
- Weatherall Sarah
- Webb Bradley
- Webber Caleb
- Wedenoja Juho
- Wei Zhi
- Weiser Mark
- Weiss Lauren A.
- Wendland Jens R.
- Werge Thomas
- Whelan Christopher D.
- Wijsman Ellen
- William Rayner N.
- Williams Julie
- Williams Nigel
- Wilmot Beth
- Winsvold Bendik
- Witt Stephanie H.
- Wolanczyk Tomasz
- Wood Nicholas W.
- Worbe Yulia
- Wray Naomi R.
- Yilmaz Zeynep
- Yu Dongmei
- Zai Gwyneth
- Zandi Peter P.
- Zara Federico
- Zayats Tetyana
- Zimprich Fritz
- Zwart John-Anker
- Publication venue
- American Association for the Advancement of Science
- Publication date
- 01/01/2018
- Field of study
ience, this issue p. eaap8757 Structured Abstract INTRODUCTION Brain disorders may exhibit shared symptoms and substantial epidemiological comorbidity, inciting debate about their etiologic overlap. However, detailed study of phenotypes with different ages of onset, severity, and presentation poses a considerable challenge. Recently developed heritability methods allow us to accurately measure correlation of genome-wide common variant risk between two phenotypes from pools of different individuals and assess how connected they, or at least their genetic risks, are on the genomic level. We used genome-wide association data for 265,218 patients and 784,643 control participants, as well as 17 phenotypes from a total of 1,191,588 individuals, to quantify the degree of overlap for genetic risk factors of 25 common brain disorders. RATIONALE Over the past century, the classification of brain disorders has evolved to reflect the medical and scientific communities' assessments of the presumed root causes of clinical phenomena such as behavioral change, loss of motor function, or alterations of consciousness. Directly observable phenomena (such as the presence of emboli, protein tangles, or unusual electrical activity patterns) generally define and separate neurological disorders from psychiatric disorders. Understanding the genetic underpinnings and categorical distinctions for brain disorders and related phenotypes may inform the search for their biological mechanisms. RESULTS Common variant risk for psychiatric disorders was shown to correlate significantly, especially among attention deficit hyperactivity disorder (ADHD), bipolar disorder, major depressive disorder (MDD), and schizophrenia. By contrast, neurological disorders appear more distinct from one another and from the psychiatric disorders, except for migraine, which was significantly correlated to ADHD, MDD, and Tourette syndrome. We demonstrate that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine. We also identify significant genetic sharing between disorders and early life cognitive measures (e.g., years of education and college attainment) in the general population, demonstrating positive correlation with several psychiatric disorders (e.g., anorexia nervosa and bipolar disorder) and negative correlation with several neurological phenotypes (e.g., Alzheimer's disease and ischemic stroke), even though the latter are considered to result from specific processes that occur later in life. Extensive simulations were also performed to inform how statistical power, diagnostic misclassification, and phenotypic heterogeneity influence genetic correlations. CONCLUSION The high degree of genetic correlation among many of the psychiatric disorders adds further evidence that their current clinical boundaries do not reflect distinct underlying pathogenic processes, at least on the genetic level. This suggests a deeply interconnected nature for psychiatric disorders, in contrast to neurological disorders, and underscores the need to refine psychiatric diagnostics. Genetically informed analyses may provide important "scaffolding" to support such restructuring of psychiatric nosology, which likely requires incorporating many levels of information. By contrast, we find limited evidence for widespread common genetic risk sharing among neurological disorders or across neurological and psychiatric disorders. We show that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures. Further study is needed to evaluate whether overlapping genetic contributions to psychiatric pathology may influence treatment choices. Ultimately, such developments may pave the way toward reduced heterogeneity and improved diagnosis and treatment of psychiatric disorders
Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study
- Author
- Aahlin Eirik Kjus
- Aamer Ahmed
- Aaniana Kenneth
- Ababneh Ali
- Abaliksta Tomas
- Abantanga Francis
- Abbas Athar
- Abbasy Jibran
- Abbo Olivier
- Abbott Tom
- Abbouch Meryem
- Abd El-Latif Nadia Khalid
- Abd Elkhalek Esraa
- Abd-Elmawla Manar
- Abdallah Emad
- Abdel-Aty Abdulrahman
- Abdel-Hameed Noran
- Abdel-Kader Sara Mahmoud
- Abdelaal Abdelaziz
- Abdelaty Mohamed
- Abdelazeam Anan Rady
- Abdelazim Galaleldin
- Abdelaziz Mohamed A
- Abdelbadeai Kholoud
- Abdelfatah Afnan
- Abdelhady Samar
- Abdelhamed Rasha
- Abdelhamid Amina
- Abdelhaq Aram
- Abdelkader Mostafa
- Abdelkader Omar
- Abdelkhalek Mohamed
- Abdelmageed Eman
- Abdelmotaleb Ibrahem
- Abdelraouf Ahmed Mahmoud
- Abdelrouf Doaa Maher
- Abdelshakour Mahmoud
- Abdrabou Abdulshafi Khaled
- Abdul-Latif Saiba
- Abdulaziz Hager
- Abdulaziz Mustafa
- Abdulbagi Omar
- Abdulhakeem Eman Mahmoud
- Abdullah Mohamed Abozed
- Abdullah Nik Azim Nik
- Abdullah Noha
- Abdullahi Lawal
- Abdurrazzaaq Abdussemiu
- Abem Owusu Emmanuel
- Abiola Olajide
- Aboelella Majed
- Aboelmagd Omnia
- Aboelsoud Moustafa R
- Aboul-Naga Mariam Saad
- Abouzaid Arwa
- Abu Qumbos Amjad
- Abu-toyour Maram
- Abubakr Marwan
- Abuowda Yousef
- Abuqwaider Eman
- Abusalem Lana
- Abushamleh Soha
- Ackom Eric
- Acquah Emmanuel
- Adam Ali
- Adam Nourhan
- Adamu Ahmed
- Adawi Ihdaa
- Adawi Mohammad
- Adebanjo Ademola
- Adebola Oluwaseyi
- Adedeji Adesina
- Adel Badr Eldin
- Adel Israa
- Adella Fidelis Jacklyn
- Adelshone Abdelrahman
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Ademuyiwa Adesoji O
- Adenekan Babajide
- Adeniran James
- Adeniyi Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adeyeye Ademola
- Adeyeye Ademola
- Adhitama Novia
- Adil Muhammad
- Adisa Adewale O
- Adiyaman Can
- Adu-Aryee Niiarmah
- Afana Samah
- Agalianos Christos
- Agarwal Arnav
- Agarwal Arnav
- Agbedinu Kwabena
- Aglan Amro
- Aguado Suarez Nuria
- Aguilera Maria Lorena
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlonsou Germain
- Ahlqvist Sandra
- Ahlqvist Sandra
- Ahmed Asdaq
- Ahmed Ataa
- Ahmed Hayam
- Ahmed Hussien
- Ahmed Lopna Ahmed Mohamed
- Ahmed Sara
- Ahmed Saraibrahim
- Ahounou Ernest Yemalin Stephane
- Ajah Jonathan
- Ajai Olalekan
- Ajao Akinlabi
- Ajiboye Anthony
- Akoto Elliot
- Akpenyi Onyinye
- Al Amin Shadid
- Al Attar Samaa Mahmoud
- Al Barraw Fayez Elian
- Al Bastawis Fatema
- Al Meligy Amgad
- Al Rafati Ahmad Abdel Razaq
- Al Raouf Eman Abd
- Al Saied Ghiath
- Al Subaie Norah
- Al-Bahrani Ahmed
- Al-Buhaisi Alaa
- Al-Dakka Emad
- Al-faqawi Maha
- Al-farram Hadeel
- Al-khatib Ahmed
- Al-Marakby Dina
- Al-saqqa Sara
- Al-Saqqa Sara W
- Al-Slaibi Ibrahim
- Al-taher Taher
- AlaaelDein Shahinaz
- Alada Muslimat
- Alakaloko Felix
- Alaloul Enas
- Alamin Shadid
- Alamoudi Mohammed
- Albiety Adel
- Alcca Ticona Willy
- Alejos Bermudez Ysabel Esthefany
- Alexander Philip
- Alexander Philip
- Alexandre Challine
- Alghamdi Ahmed
- Alghamdi Mohammed Saleh A
- Alhady Khaled
- Alhammali Tariq
- Alhassan Basmah
- Alhazmi Wedyan
- Alherz Mohammad
- Ali Ahmed
- Ali Citra Dewi Mohd
- Ali Elsayed
- Ali Safia
- Ali Syed Abdul Wahhab Eusoffee Wan
- Ali Tebian Hassanein Ahmed
- Ali Wadah
- Alihonou Thierry
- Alis Halil
- Aliyu Halima
- Aliyu Mohammad
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- Aljboor Khaled
- Aljiffry Murad
- Alkaaki Aroub
- Alkelani Muhammad
- Allam Meran
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- Alnaby Mohamed Hassab
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- Alqahtani Saleh
- Alsaggaf Mohammed Ubaid
- Alser Osaid H
- Alshareef Reham
- Altaf Abdulmalik
- Altamimi Abdullah
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- Altamini Afnan
- Altarayra Marwa
- Altibi Ahmed
- Altinel Yuksel
- Altinel Yuksel
- Altwijri Abdulaziz
- Alvi Abdul Rehman
- Aly Mohammed Yahia Mohamed
- Alyacoubi Said
- Alyahya Reem
- Alzahrani Ahmed
- Aman Nowrin F
- Amandito Radhian
- Amandito Radhian
- Ambrona-Zafra David
- Amin Hager Abdul Aziz
- Amjad Mohammadasim
- Amoah Michael
- Amoako Joachim
- Amoako Philip Taah
- Amoako-Boateng Mabel
- Amole Isaac
- Amreia Mahmoud
- Anderson Frank
- Andika Ferry Fitriya Ayu
- Andreotti Dario
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- Ang Yun Lin
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- Anthoulakis Christos
- Antoniozzi Angelo
- Anwar Nourhan
- Anyanwu Lofty-John
- Aonzo Paolo
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- Arafa Sara
- Arango Maria Clara Mendoza
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- Armellini Andrea
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- Arshad Mohammad Mohsin
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- Atkins Ebenezer Takyi
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- Aviles Susan
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- Awad Israa
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- Awadallah Salwa
- Ayandipo Omobolaji
- Aydin Mehmet Can
- Aziz Dayang Nita Abdul
- Aziz Mohamed Rezal Abdul
- Aziz Nora Abdul
- Azizeldine Mohammed G
- Azzie Georges
- Azzis Olivier
- Baba Suleiman
- Bachri Houda
- Badawy Mahmoud
- Badenjki Mohamed Adel
- Badicel Maria
- Badr Mohamed Fawzy Mahrous
- Badwi Nermin Mohamed
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- Banipal Gurpreet Singh
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- Bedada Alemayehu Ginbo
- BediakoBowan Antoinette
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- Beleno Alvaro Enrique Mendoza
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- Belli Andrea
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- Bennai Redouane Mammar
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- Bhangu Aneel
- Bhangu Aneel
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- Bhatnagar Ankur
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- Bianco Federica
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- Brunoni Beatrice
- Bsisu Isam
- Bucci Luigi
- Buisson Philippe
- Bunting David
- Burger Sule
- Burmistrovas Andrius
- Bustangi Nasir
- Bustangi Nasir
- Butt Muhammad Talha
- Cakaloglu Haluk Cem
- Caliman Celeste
- Callan Rory
- Camilleri Georgette Marie
- Camilleri-Brennan Julian
- Campagnaro Tommaso
- Canta Calua Alexander
- Capito Carmen
- Carabott Kurt
- Carmela Lapitan Marie
- Carmona Juan Manuel
- Carpio Juan
- Carrasco Nahilia
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- Cengiz Yucel
- Cengiz Yucel
- Cevik Muazzez
- Chabok Abbas
- Chai Chu-Ann
- Chai Feng Yih
- Chan Luke
- Chan Tsz-Yan Katie
- Chan Xue Wei
- Charles Angeline
- Cheah Alvin Ee Zhiun
- Chen Kar Yan
- Chen Tzu-Ling
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- Chetta Nicola
- Cheung Yuk Hong Eric
- Chibuye Chali
- Chiesa Deborah
- Chilton Gareth
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- Choi Philip
- Chong Choon Seng
- Chong Hoong-Yin
- Choudhry Asad
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- Chu Kathryn
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- Curletti Gianluca
- Currow Chelise
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- D'Souza Michelle S
- Dabboor Majd
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- Drake Thomas M
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- du Plooy Flip
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- Ebidy Mai
- Ebidy Mai Mohamed
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- Ellison Quinn
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- Elnajjar Mahmoud A
- Elrazek Aly Abd
- Elsabbagh Nourhan
- Elsameea Ahmed Abd
- Elsawy Amira
- Elsayed Nada Ahmed Reda
- Elsemelawy Rofida
- Elshaar Mohammed
- Elshaer Mohamed
- Elshami Mohamedraed
- Elsharkawy Aya Adel
- Elsherbiney Saged
- Elsherif Fawzia Abdellatif
- Elwy Eman
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- Emadeldin Hossam
- Emara Eman
- Emile Sameh
- Eng Calvin
- English William
- Esam Abeer
- Escalante Salas Marilia Del Carmen
- Espin-Basany Eloy
- Espinoza Fernando
- Essam AA
- Essam Ahmed
- Essam Mahitab
- Essoun Samuel
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- Falzon Malcolm
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- Farag Sameh
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- Farhan-Alanie Muhamed MH
- Farhangmehr Neda
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- Fathy Aya Mohamed
- Fatuga Adedeji
- Faturoti Olubukola
- Favero Alessandro
- Feidantsis Thomas
- Fergany Alaa
- Fergusson Stuart J
- Fergusson Stuart J
- Fermani Claudio Gabriel
- Fernandes Cristina
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- Ferousis Christoforos
- Ferrero Esther
- Filatau Aliaksandr
- Firdouse Mohammed
- Firdouse Mohammed
- Firwana Aya
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- Fitzgerald J Edward
- Fitzgerald J Edward
- Florez Farfan Erick Samuel
- Foco Maurizio
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- Foo Chi Chung
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- Francisco Roxas Manuel
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- Fuentes-Rivera Lorena
- Gaafar Shireen
- Gaarder Tina
- Gad Ahmed
- Gad Mariam O
- Gadelkarim Mohamed
- Gado Ammar
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- Tabiri Stephen
- Tackie Enoch
- Taddei Antonio
- Tahboub Haya
- Taher Ayman And
- Taher Mustafa Mohammed
- Taieb Chouikh
- Taiwo Agboola
- Taiwo Ogechukwu
- Talaat Muhammed
- Tale Luis
- Talving Peep
- Talving Peep
- Tan Charlene
- Tan Choy Ling
- Tan Joel Kin
- Tan Keith Say Kwang
- Tan Ryan Choon Kiat
- Tan Yee Wen
- Tan Yi Koon
- Tang Lingshan
- Tani Sobhana Iftekhar
- Tansoker Ilkan
- Tarek Adham
- Tarek Dina
- Targa Simone
- Tariq Sherif
- Tata Mahadevan Deva
- Tawfik Badreldin Adel
- Tawfik Gehad
- Teasdale Ella
- Teasdale Ella
- Teasdale Ella
- Tedeschi Umberto
- Tembo Thelma
- Tennakoon Athula
- Teo Shuang Yi
- Ter Eunice Zuling
- Tew Yong Yong
- Tew Yong Yong
- Thabet Waleed
- Thalgaspitiya SPB
- Theodosopoulos Theodosios
- Thollot Aurore
- Thorarinsdottir Hildur
- Thorell Anders
- Timothy Oyediran Kehinde
- Ting Jesse Ron Swire
- To Kathleen
- Tolonen Matti
- Tolotra Todisoa Emmanuella Christina
- Tomas Kadir
- Tori Sayeeda Aktar
- Toribio Orbegozo Pedro Angel
- Torrance Hew D
- Torres Cardozo Jorge
- Torres Rodriguez Servio Tulio
- Toto Omer Faruk
- Townsend Dominic
- Trompetto Mario
- Tselos Angelos
- Tshisola Serge Kapenda
- Tugnoli Gregorio
- Tun Myint
- Turati Luca
- Turkustani Sondos
- Turpo Espinoza Kenny
- Turpo Espinoza Kevin
- Tutino Roberta
- Tverskis Zygimantas
- Tyler Robert
- Tze R Goh Ern
- Tzikos Georgios
- Ubiali Paolo
- Ukwenya Yahaya
- ul Razi Syed Asaat
- Ulusahin Mehmet
- Upadhyaya Vijaid
- Urbonas Tomas
- Urniezius Zigmantas
- Uscinas Laimonas
- Uzabumwana Norbert
- Vaicius Arturas
- Valcarcel-Saldana Maria
- Valioulis Ioannis
- Van Der Naald Niels
- Van Niekerk Michael
- Van Straten Stephanie
- Vargas Marvin
- Vartanoglu Talar
- Vartic Mihaela
- Vasquez Giorgio
- Vasquez Idelso
- Veen Torhild
- Velasquez Ricardo
- Venclauskas Linas
- Vendramin Elena
- Venskutonis Donatas
- Venskutonis Donatas
- Verbeek Anna
- Vergara Mejia Angelica Genoveva
- Verjee Azmina
- Vermaas Maarten
- Vicario Erika
- Vicenta Collado Maria
- Vida Lucian Corneliu
- Vilcinskas Mantas
- Villalobos Santiago
- Violi Paola
- Visinskas Petras
- Voulgaris Evangelos
- Wael Noha
- Wakefield Rebecca
- Waledziak Maciej
- Walker Michael
- Walker Nathan
- Walls Luke
- Walsh Michael
- Waqar Muhammad
- Warren Oliver
- Waterman Ade
- Werder Gabriela
- Whitaker John
- White Rebecca
- Whitehurst Katharine
- Wiborg Joachim
- Widiastini T Ariani
- Widmer Lukas Werner
- Wijayarathna LS
- Williams Omolara
- Wilson Ling
- Wilson Michael
- Wilson Michael
- Wimalge PMSN
- Wogensen Fredrik
- Wolf Bernhard
- Wondoh Paul
- Wondoh Paul
- Wong Chui Yee
- Wong Francisca
- Wong Hong Yee
- Wood Greta
- Worku Mengistu
- Worku Tewodros
- Wright Naomi
- Yahaya Muhammad Taqiyuddin
- Yakubu Musah
- Yam Sir Young
- Yang James
- Yap Suhhuey
- Yau Jih Dar
- Ye Joselyn
- Yeang Li Jing
- Yeung Man Hon Andrew
- Yifieyeh Abiboye
- Yildirim Reyyan
- Yip Chingwan
- Ymeri Shpetim
- Yoganathan Pigeneswaren
- Yolcu Sinem
- Yong Guo Liang
- Younis Abobaker
- Youssef Mohamed
- Yuksek Mahmut Arif
- Yusufali Taha
- Zaa'treh Rula
- Zadoroznas Antanas
- Zahran Diaaaldin
- Zakaria Esraay
- Zakaria Mahmoud
- Zakaria Yehia
- Zaki Ahmed
- Zammit Stefan
- Zampitis Nikolaos
- Zani Augusto
- Zani Augusto
- Zanini Nicola
- Zapata Felipe
- Zarb Ciskje
- Zeta Solis Ludwing Alexander
- Zielinski Martin
- Zilinskas Justas
- Zilinskas Justas
- Zilinskas Justas
- Zilinskiene Reda
- Ziubryte Greta
- Zohair Ahmed
- Zuber Markus
- Zuk Grzegorz
- Zulkifli Athirah
- Zumbuhl Lucius
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world.
Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231.
Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001).
Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A
- Abdrakhmanova Shynar
- Abu-Rmeileh Niveen M
- Acosta-Cazares Benjamin
- Adams Robert J
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A
- Agyemang Charles
- Ahmad Mohamad Hasnan
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmed Soheir H
- Ahrens Wolfgang
- Aitmurzaeva Gulmira
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Hazzaa Hazzaa M
- Al-Othman Amani Rashed
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Alvarez-Pedrerol Mar
- Aly Eman
- Amarapurkar Deepak N
- Amiri Parisa
- Amougou Norbert
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A
- Angquist Lars
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Aounallah-Skhiri Hajer
- Araujo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E
- Arlappa Nimmathota
- Aryal Krishna K
- Aspelund Thor
- Assah Felix K
- Assuncao Maria Cecilia F
- Aung May Soe
- Auvinen Juha
- Avdicova Maria
- Azevedo Ana
- Azimi-Nezhad Mohsen
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V
- Baharudin Azli
- Bahijri Suhad
- Baker Jennifer L
- Balakrishna Nagalla
- Bamoshmoosh Mohamed
- Banach Maciej
- Bandosz Piotr
- Banegas Jose R
- Baran Joanna
- Barbagallo Carlo M
- Barcelo Alberto
- Barkat Amina
- Barros Aluisio JD
- Barros Mauro Virgilio Gomes
- Basit Abdul
- Bastos Joao Luiz D
- Bata Iqbal
- Batieha Anwar M
- Batista Rosangela L
- Battakova Zhamilya
- Batyrbek Assembekov
- Baur Louise A
- Beaglehole Robert
- Bebakar Wan Mohamad Wan
- Bel-Serrat Silvia
- Belavendra Antonisamy
- Ben Romdhane Habiba
- Benedics Judith
- Benet Mikhail
- Bennett James E
- Bennett James E
- Bentham James
- Bergh Ingunn Holden
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol Heloisa
- Bezerra Jorge
- Bhagyalaxmi Aroor
- Bharadwaj Sumit
- Bhargava Santosh K
- Bhutta Zulfiqar A
- Bhutta Zulfiqar A
- Bi Hongsheng
- Bi Yufang
- Bia Daniel
- Bikbov Mukharram M
- Bista Bihungum
- Bixby Honor
- Bjelica Dusko J
- Bjerregaard Peter
- Bjertness Espen
- Bjertness Marius B
- Bjorkelund Cecilia
- Black Robert
- Bloch Katia V
- Blokstra Anneke
- Bo Simona
- Bobak Martin
- Boddy Lynne M
- Boehm Bernhard O
- Boeing Heiner
- Boggia Jose G
- Bogova Elena
- Boissonnet Carlos P
- Bojesen Stig E
- Boker Lital Keinan
- Bonaccio Marialaura
- Bongard Vanina
- Bonilla-Vargas Alice
- Bopp Matthias
- Borghs Herman
- Bovet Pascal
- Braeckevelt Lien
- Braeckman Lutgart
- Bragt Marjolijn CE
- Brajkovich Imperia
- Branca Francesco
- Braunerova Radka Taxova
- Breckenkamp Juergen
- Breda Joao
- Brenner Hermann
- Brewster Lizzy M
- Brian Garry R
- Brinduse Lacramioara
- Brophy Sinead
- Bruno Graziella
- Bueno-de-Mesquita H Bas
- Bugge Anna
- Buoncristiano Marta
- Burazeri Genc
- Burns Con
- Cacciottolo Joseph
- Cadena Leticia Hernandez
- Cai Hui
- Cama Tilema
- Cameron Christine
- Camolas Jose
- Can Gunay
- Candido Ana Paula C
- Canete Felicia
- Capanzana Mario V
- Capkova Nadezda
- Capuano Eduardo
- Capuano Vincenzo
- Cardol Marloes
- Cardoso Viviane C
- Carlsson Axel C
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- Carvalho Joana
- Casajus Jose A
- Casanueva Felipe F
- Celikcan Ertugrul
- Censi Laura
- Cervantes-Loaiza Marvin
- Cesar Juraci A
- Chamukuttan Snehalatha
- Chan Angelique W
- Chan Queenie
- Chaturvedi Himanshu K
- Chaturvedi Nish
- Chen Chien-Jen
- Chen Fangfang
- Chen Huashuai
- Chen Shuohua
- Chen Zhengming
- Cheng Ching-Yu
- Cheraghian Bahman
- Chetrit Angela
- Chikova-Iscener Ekaterina
- Chinh Nguyen Huu
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
- Chirita-Emandi Adela
- Chirlaque Maria-Dolores
- Cho Belong
- Christensen Kaare
- Christofaro Diego G
- Chudek Jerzy
- Cifkova Renata
- Cilia Michelle
- Cinteza Eliza
- Cisneros Julio Zuniga
- Claessens Frank
- Clarke Janine
- Clays Els
- Cohen Emmanuel
- Concin Hans
- Confortin Susana C
- Cooper Cyrus
- Coppinger Tara C
- Corpeleijn Eva
- Costanzo Simona
- Cottel Dominique
- Cowan Melanie J
- Cowell Chris
- Craig Cora L
- Crampin Amelia C
- Crujeiras Ana B
- Csilla Semanova
- Cucu Alexandra M
- Cui Liufu
- Cureau Felipe V
- D'Arrigo Graziella
- d'Orsi Eleonora
- da Silva Bruna Goncalves Cordeiro
- Dacica Liliana
- Dallongeville Jean
- Damasceno Albertino
- Damsgaard Camilla T
- Danaei Goodarz
- Danaei Goodarz
- Dankner Rachel
- Dantoft Thomas M
- Dasgupta Parasmani
- Dastgiri Saeed
- Dauchet Luc
- Davletov Kairat
- De Backer Guy
- De Bacquer Dirk
- de Gaetano Giovanni
- De Henauw Stefaan
- de Leon Antonio Cabrera
- de Oliveira Paula Duarte
- de Paiva Karina Mary
- De Ridder David
- De Ridder Karin
- de Rooij Susanne R
- De Smedt Delphine
- de Souza Rildo
- de Wit Tobias F Rinke
- Deepa Mohan
- Deev Alexander D
- DeGennaro Vincent
- Dehghan Abbas
- Delisle Helene
- Delpeuch Francis
- Demarest Stefaan
- Dennison Elaine
- Deren Katarzyna
- Deschamps Valerie
- Dhana Klodian
- Dhimal Meghnath
- Di Castelnuovo Augusto F
- Di Cesare Mariachiara
- Dias-da-Costa Juvenal Soares
- Diaz Alejandro
- Diaz-Sanchez Maria Elena
- Dika Zivka
- Djalalinia Shirin
- Djordjic Visnja
- Do Ha TP
- Dobson Annette J
- Donati Maria Benedetta
- Donfrancesco Chiara
- Donoso Silvana P
- Doring Angela
- Dorobantu Maria
- Dorosty Ahmad Reza
- Doua Kouamelan
- Drygas Wojciech
- Duan Jia Li
- Duante Charmaine A
- Duboz Priscilla
- Duda Rosemary B
- Duleva Vesselka
- Dulskiene Virginija
- Dumith Samuel C
- Dushpanova Anar
- Dzerve Vilnis
- Dziankowska-Zaborszczyk Elzbieta
- Eddie Ricky
- Eftekhar Ebrahim
- Egbagbe Eruke E
- Eggertsen Robert
- Eghtesad Sareh
- Eiben Gabriele
- Ekelund Ulf
- El Ati Jalila
- El-Khateeb Mohammad
- Eldemire-Shearer Denise
- Eliasen Marie
- Elliott Paul
- Engle-Stone Reina
- Enguerran Macia
- Erasmus Rajiv T
- Erbel Raimund
- Erem Cihangir
- Eriksen Louise
- Eriksson Johan G
- Escobedo-de la Pena Jorge
- Eslami Saeid
- Esmaeili Ali
- Evans Alun
- Ezzati Majid
- Faeh David
- Fakhretdinova Albina A
- Fall Caroline H
- Faramarzi Elnaz
- Farjam Mojtaba
- Farzadfar Farshad
- Fattahi Mohammad Reza
- Fawwad Asher
- Felix-Redondo Francisco J
- Ferguson Trevor S
- Fernandes Romulo A
- Fernandez-Berges Daniel
- Ferrante Daniel
- Ferrao Thomas
- Ferrari Marika
- Ferrario Marco M
- Ferreccio Catterina
- Ferrer Eldridge
- Ferrieres Jean
- Figueiro Thamara Hubler
- Fijalkowska Anna
- Fink Gunther
- Fischer Krista
- Foger Bernhard
- Foo Leng Huat
- Forsner Maria
- Fouad Heba M
- Francis Damian K
- Franco Maria do Carmo
- Franco Oscar H
- Frikke-Schmidt Ruth
- Frontera Guillermo
- Fuchs Flavio D
- Fuchs Sandra C
- Fujiati Isti I
- Fujita Yuki
- Fumihiko Matsuda
- Furusawa Takuro
- Gaciong Zbigniew
- Gafencu Mihai
- Galbarczyk Andrzej
- Galenkamp Henrike
- Galeone Daniela
- Galfo Myriam
- Galvano Fabio
- Gao Jingli
- Garba Jamila Abubakar
- Garcia-de-la-Hera Manoli
- Garcia-Solano Marta
- Gareta Dickman
- Garnett Sarah P
- Gaspoz Jean-Michel
- Gasull Magda
- Gaya Adroaldo Cesar Araujo
- Gaya Anelise Reis
- Gazzinelli Andrea
- Gehring Ulrike
- Geiger Harald
- Geleijnse Johanna M
- Ghaffar Suhaila Abdul
- Ghanbari Ali
- Ghasemi Erfan
- Gheorghe-Fronea Oana-Florentina
- Giampaoli Simona
- Gianfagna Francesco
- Gill Tiffany K
- Giovannelli Jonathan
- Gironella Glen
- Giwercman Aleksander
- Gkiouras Konstantinos
- Godos Justyna
- Gogen Sibel
- Goldsmith Rebecca A
- Goltzman David
- Gomez Santiago F
- Gomula Aleksandra
- Goncalves Helen
- Gonzalez Angel R
- Gonzalez-Chica David A
- Gonzalez-Gross Marcela
- Gonzalez-Leon Margot
- Gonzalez-Rivas Juan P
- Gonzalez-Villalpando Clicerio
- Gonzalez-Villalpando Maria-Elena
- Gottrand Frederic
- Graca Antonio Pedro
- Graff-Iversen Sidsel
- Grafnetter Dusan
- Grajda Aneta
- Grammatikopoulou Maria G
- Gregg Edward W
- Gregor Ronald D
- Grodzicki Tomasz
- Groholt Else Karin
- Grontved Anders
- Grosso Giuseppe
- Gruden Gabriella
- Gu Dongfeng
- Gualdi-Russo Emanuela
- Guallar-Castillon Pilar
- Gualtieri Andrea
- Gudmundsson Elias F
- Gudnason Vilmundur
- Guerrero Ramiro
- Guessous Idris
- Guimaraes Andre L
- Gulliford Martin C
- Gunnlaugsdottir Johanna
- Gunter Marc J
- Guo Xiu-Hua
- Guo Yin
- Gupta Prakash C
- Gupta Rajeev
- Gureje Oye
- Gurzkowska Beata
- Gutierrez Laura
- Gutierrez-Gonzalez Enrique
- Gutzwiller Felix
- Ha Seongjun
- Hadaegh Farzad
- Hadjigeorgiou Charalambos A
- Haghshenas Rosa
- Hakimi Hamid
- Halkjaer Jytte
- Hambleton Ian R
- Hamzeh Behrooz
- Hange Dominique
- Hanif Abu AM
- Hantunen Sari
- Hashemi-Shahri Seyed Mohammad
- Hassapidou Maria
- Hata Jun
- Haugsgjerd Teresa
- Hayes Alison J
- He Jiang
- He Yuan
- He Yuna
- Heidinger-Felso Regina
- Heinen Mirjam
- Hejgaard Tatjana
- Hendriks Marleen Elisabeth
- Henrique Rafael dos Santos
- Henriques Ana
- Herrala Sauli
- Herrera Victor M
- Herter-Aeberli Isabelle
- Heshmat Ramin
- Hill Allan G
- Ho Sai Yin
- Ho Suzanne C
- Hoang Van Minh
- Hobbs Michael
- Hofman Albert
- Holdsworth Michelle
- Homayounfar Reza
- Homs Clara
- Hopman Wilma M
- Horimoto Andrea RVR
- Hormiga Claudia M
- Horta Bernardo L
- Houti Leila
- Howitt Christina
- Htet Aung Soe
- Htike Maung Maung Than
- Hu Yonghua
- Huerta Jose Maria
- Huhtaniemi Ilpo Tapani
- Husseini Abdullatif
- Huybrechts Inge
- Hwalla Nahla
- Hyska Jolanda
- Iacoviello Licia
- Ibarluzea Jesus M
- Ibrahim Mohsen M
- Ikeda Nayu
- Ikram M Arfan
- Ioannidou Eliza Markidou
- Iotova Violeta
- Irazola Vilma E
- Ishida Takafumi
- Islam Muhammad
- Islam Sheikh Mohammed Shariful
- Iurilli Maria LC
- Iwasaki Masanori
- Jackson Rod T
- Jacobs Jeremy M
- Jaddou Hashem Y
- Jafar Tazeen
- James Kenneth
- Jamil Kazi M
- Jamrozik Konrad
- Janszky Imre
- Janus Edward
- Jarani Juel
- Jarvelin Marjo-Riitta
- Jasienska Grazyna
- Jelakovic Ana
- Jelakovic Bojan
- Jennings Garry
- Jerome Charles Sossa
- Jha Anjani Kumar
- Jiang Chao Qiang
- Jimenez Ramon O
- Jockel Karl-Heinz
- Joffres Michel
- Johansson Mattias
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- Jonas Jost B
- Jonsson Kenisha Russell
- Jorgensen Maja Baeksgaard
- Jorgensen Torben
- Joshi Pradeep
- Joukar Farahnaz
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- Jurak Gregor
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- Kaducu Felix O
- Kafatos Anthony
- Kajantie Eero O
- Kalmatayeva Zhanna
- Kalter-Leibovici Ofra
- Kameli Yves
- Kanala Kodanda R
- Kannan Srinivasan
- Kapantais Efthymios
- Karki Khem B
- Katibeh Marzieh
- Katz Joanne
- Katzmarzyk Peter T
- Kauhanen Jussi
- Kaur Prabhdeep
- Kavousi Maryam
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- Keil Ulrich
- Keinanen-Kiukaanniemi Sirkka
- Kelishadi Roya
- Kelleher Cecily
- Kemper Han CG
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- Kengne Andre P
- Keramati Maryam
- Kerimkulova Alina
- Kersting Mathilde
- Key Timothy
- Khader Yousef Saleh
- Khalili Davood
- Khang Young-Ho
- Khang Young-Ho
- Khanh Le Nguyen Bao
- Khaw Kay-Tee
- Kheiri Bahareh
- Kheradmand Motahareh
- Khosravi Alireza
- Khouw Ilse MSL
- Khuong Quynh Long
- Kiechl Stefan
- Kiechl-Kohlendorfer Ursula
- Killewo Japhet
- Kim Dong Wook
- Kim Hyeon Chang
- Kim Jeongseon
- Kindblom Jenny M
- Klakk Heidi
- Klimek Magdalena
- Klimont Jeannette
- Klumbiene Jurate
- Knoflach Michael
- Koirala Bhawesh
- Kolle Elin
- Kolsteren Patrick
- Konig Jurgen
- Korpelainen Raija
- Korrovits Paul
- Korzycka Magdalena
- Kos Jelena
- Koskinen Seppo
- Kouda Katsuyasu
- Kovacs Viktoria A
- Kowlessur Sudhir
- Koziel Slawomir
- Kratzer Wolfgang
- Kriemler Susi
- Kristensen Peter Lund
- Krokstad Steiner
- Kromhout Daan
- Krtalic Branimir
- Kruger Herculina S
- Kubinova Ruzena
- Kuciene Renata
- Kujala Urho M
- Kujundzic Enisa
- Kulaga Zbigniew
- Kumar R Krishna
- Kumar Rachakulla Hari
- Kunesova Marie
- Kurjata Pawel
- Kusuma Yadlapalli S
- Kuulasmaa Kari
- Kyobutungi Catherine
- Laamiri Fatima Zahra
- Laatikainen Tiina
- Lachat Carl
- Laid Youcef
- Lam Tai Hing
- Lambrinou Christina-Paulina
- Landais Edwige
- Lanska Vera
- Lappas Georg
- Larijani Bagher
- Latt Tint Swe
- Lauria Laura
- Laxmaiah Avula
- Laxmaiah Avula
- Lazo-Porras Maria
- Le Port Agnes
- Le Tuyen D
- Lee Jeannette
- Lee Jeonghee
- Lee Paul H
- Lehmann Nils
- Lehtimaki Terho
- Lele Elysee Claude Bika
- Lemogoum Daniel
- Levitt Naomi S
- Li Yanping
- Liivak Merike
- Lilly Christa L
- Lim Wei-Yen
- Lima-Costa M Fernanda
- Lin Hsien-Ho
- Lin Xu
- Lin Yi-Ting
- Lind Lars
- Linneberg Allan
- Lissner Lauren
- Litwin Mieczyslaw
- Liu Jing
- Liu Lijuan
- Lo Wei-Cheng
- Loit Helle-Mai
- Lopes Luis
- Lopes Oscar
- Lopez Tania
- Lopez-Garcia Esther
- Lotufo Paulo A
- Lozano Jose Eugenio
- Lukrafka Janice L
- Luksiene Dalia
- Lundqvist Annamari
- Lundqvist Robert
- Lunet Nuno
- Lunogelo Charles
- Lustigova Michala
- Luszczki Edyta
- Ma Guansheng
- Ma Jun
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- Machado-Coelho George LL
- Machado-Rodrigues Aristides M
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- Madar Ahmed A
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- Stronks Karien
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- Sundstrom Johan
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- Van der Heyden Johan
- van der Schouw Yvonne T
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- van Valkengoed Irene GM
- Vanderschueren Dirk
- Vanuzzo Diego
- Varbo Anette
- Varela-Moreiras Gregorio
- Varona-Perez Patricia
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- Veidebaum Toomas
- Velasquez-Melendez Gustavo
- Velika Biruta
- Veronesi Giovanni
- Verschuren WM Monique
- Victora Cesar G
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- Viet Lucie
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- Vineis Paolo
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- Vrijheid Martine
- Vrijkotte Tanja GM
- Vrkic Tajana Zeljkovic
- Wade Alisha N
- Wagner Aline
- Waldhor Thomas
- Walton Janette
- Wambiya Elvis OA
- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S Goya
- Wareham Nicholas
- Weber Adelheid
- Wedderkopp Niels
- Weerasekera Deepa
- Weghuber Daniel
- Wei Wenbin
- Weres Aneta
- Werner Bo
- Whincup Peter H
- Widhalm Kurt
- Widyahening Indah S
- Wiecek Andrzej
- Wilks Rainford J
- Willeit Johann
- Willeit Peter
- Williams Julianne
- Wilsgaard Tom
- Wojtyniak Bogdan
- Wong Andrew
- Wong Jyh Eiin
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A
- Woo Jean
- Woodward Mark
- Wu Frederick C
- Wu Jianfeng
- Wu Li Juan
- Wu Shouling
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yamborisut Uruwan
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yardim Nazan
- Yaseri Mehdi
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K
- Yoosefi Moein
- Yoshihara Akihiro
- You Qi Sheng
- You San-Lin
- Younger-Coleman Novie O
- Yusof Safiah Md
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zaccagni Luciana
- Zafiropulos Vassilis
- Zainuddin Ahmad A
- Zainuddin Ahmad A
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zamrazilova Hana
- Zapata Maria Elisa
- Zargar Abdul Hamid
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhao Wenhua
- Zhen Shiqi
- Zheng Wei
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhou Maigeng
- Zhu Dan
- Zocalo Yanina
- Zuziak Monika
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
Summary Background Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. Methods For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a Bayesian hierarchical model to estimate trends from 1985 to 2019 in mean height and mean BMI in 1-year age groups for ages 5–19 years. The model allowed for non-linear changes over time in mean height and mean BMI and for non-linear changes with age of children and adolescents, including periods of rapid growth during adolescence. Findings We pooled data from 2181 population-based studies, with measurements of height and weight in 65 million participants in 200 countries and territories. In 2019, we estimated a difference of 20 cm or higher in mean height of 19-year-old adolescents between countries with the tallest populations (the Netherlands, Montenegro, Estonia, and Bosnia and Herzegovina for boys; and the Netherlands, Montenegro, Denmark, and Iceland for girls) and those with the shortest populations (Timor-Leste, Laos, Solomon Islands, and Papua New Guinea for boys; and Guatemala, Bangladesh, Nepal, and Timor-Leste for girls). In the same year, the difference between the highest mean BMI (in Pacific island countries, Kuwait, Bahrain, The Bahamas, Chile, the USA, and New Zealand for both boys and girls and in South Africa for girls) and lowest mean BMI (in India, Bangladesh, Timor-Leste, Ethiopia, and Chad for boys and girls; and in Japan and Romania for girls) was approximately 9–10 kg/m2. In some countries, children aged 5 years started with healthier height or BMI than the global median and, in some cases, as healthy as the best performing countries, but they became progressively less healthy compared with their comparators as they grew older by not growing as tall (eg, boys in Austria and Barbados, and girls in Belgium and Puerto Rico) or gaining too much weight for their height (eg, girls and boys in Kuwait, Bahrain, Fiji, Jamaica, and Mexico; and girls in South Africa and New Zealand). In other countries, growing children overtook the height of their comparators (eg, Latvia, Czech Republic, Morocco, and Iran) or curbed their weight gain (eg, Italy, France, and Croatia) in late childhood and adolescence. When changes in both height and BMI were considered, girls in South Korea, Vietnam, Saudi Arabia, Turkey, and some central Asian countries (eg, Armenia and Azerbaijan), and boys in central and western Europe (eg, Portugal, Denmark, Poland, and Montenegro) had the healthiest changes in anthropometric status over the past 3·5 decades because, compared with children and adolescents in other countries, they had a much larger gain in height than they did in BMI. The unhealthiest changes—gaining too little height, too much weight for their height compared with children in other countries, or both—occurred in many countries in sub-Saharan Africa, New Zealand, and the USA for boys and girls; in Malaysia and some Pacific island nations for boys; and in Mexico for girls. Interpretation The height and BMI trajectories over age and time of school-aged children and adolescents are highly variable across countries, which indicates heterogeneous nutritional quality and lifelong health advantages and risks
Measurement of the top quark forward-backward production asymmetry and the anomalous chromoelectric and chromomagnetic moments in pp collisions at √s = 13 TeV
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdelalim Ahmed Ali
- Abdullin Salavat
- Abercrombie Daniel
- Abu Zeid Shimaa
- Acharya Himal
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agarwal Garvita
- Aggleton Robin
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmad Muhammad
- Ahuja Sudha
- Akbiyik Melike
- Akchurin Nural
- Akgun Bora
- Albajar Carmen
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Allen Brandon
- Almond John
- Alvarez Gonzalez Barbara
- Alverson George
- Alves Gilvan
- Aly Reham
- Alyari Maral
- Amapane Nicola
- Ambrogi Federico
- Amendola Chiara
- Amin Nick
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Antchev Georgy
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asenov Patrick
- Askew Andrew
- Asmuss Paul
- Atakisi Ismail Okan
- Ather Mohsan Waseem
- Attikis Alexandros
- Auffray Etiennette
- Aushev Tagir
- Autermann Christian
- Auzinger Georg
- Avati Valentina
- Avery Paul
- Avila Carlos
- Awan Muhammad Imran Malik
- Ayala Edy
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzurri Paolo
- Baarmand Marc M
- Babaev Anton
- Babounikau Illia
- Bacchetta Nicola
- Bachiller Irene
- Bachtis Michail
- Backhaus Malte
- Baden Drew
- Baechler Joachim
- Bagliesi Giuseppe
- Bahinipati Seema
- Baillon Paul
- Bainbridge Robert
- Bakas Georgios
- Bakhshiansohi Hamed
- Baldenegro Barrera Cristian
- Ball Austin
- Ban Yong
- Band Reyer
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Bargassa Pedrame
- Baringer Philip
- Barker Anthony
- Barnes Virgil E
- Barney David
- Barnyakov Alexander
- Baron Owen
- Barria Patrizia
- Barrio Luna Mar
- Bartek Rachel
- Bartosik Nazar
- Bartók Márton
- Baselga Marta
- Baskakov Alexey
- Bastos Diogo
- Bat Ayse
- Battilana Carlo
- Baty Austin
- Bauerdick Lothar AT
- Baur Sebastian
- Bayshev Igor
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Beernaert Kelly
- Beghin Diego
- Behera Prafulla Kumar
- Behnke Olaf
- Behrens Ulf
- Bein Samuel
- Belchior Batista Das Chagas Ewerton
- Belforte Stefano
- Bell Ken W
- Bellan Riccardo
- Belloni Alberto
- Bellora Andrea
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
- Benato Lisa
- Bencze Gyorgy
- Bendavid Joshua
- Benecke Anna
- Benelli Gabriele
- Beni Noemi
- Benitez Jose F
- Benussi Luigi
- Beretvas Andrew
- Bergauer Thomas
- Berger Pirmin
- Berger Thomas
- Beri Suman Bala
- Bermúdez Martínez Armando
- Bernardes Cesar Augusto
- Bernet Colin
- Berry Douglas
- Berryhill Jeffrey
- Bertacchi Valerio
- Besancon Marc
- Beschi Andrea
- Betts Russell Richard
- Bhal Eshwen
- Bhandari Rohan
- Bhardwaj Ashutosh
- Bhardwaj Rishika
- Bharti Monika
- Bhat Muzamil Ahmad
- Bhat Pushpalatha C
- Bhatnagar Vipin
- Bhattacharya Rajarshi
- Bhattacharya Saptaparna
- Bhattacharya Satyaki
- Bhattacharya Soham
- Bhawandeep Bhawandeep
- Bheesette Srinidhi
- Bhowmik Debabrata
- Bhowmik Sandeep
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- Smith Geoffrey
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- Smith Vincent J
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- Snoeys Walter
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- Spalding William J
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- Zobec Joze
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Álvarez Fernández Adrian
- Özçelik Özlem
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Abstract The parton-level top quark (t) forward-backward asymmetry and the anomalous chromoelectric (d̂ t) and chromomagnetic (μ̂ t) moments have been measured using LHC pp collisions at a center-of-mass energy of 13 TeV, collected in the CMS detector in a data sample corresponding to an integrated luminosity of 35.9 fb−1. The linearized variable AFB(1) is used to approximate the asymmetry. Candidate t t ¯ events decaying to a muon or electron and jets in final states with low and high Lorentz boosts are selected and reconstructed using a fit of the kinematic distributions of the decay products to those expected for t t ¯ final states. The values found for the parameters are AFB(1)=0.048−0.087+0.095(stat)−0.029+0.020(syst),μ̂t=−0.024−0.009+0.013(stat)−0.011+0.016(syst), and a limit is placed on the magnitude of | d̂ t| < 0.03 at 95% confidence level. [Figure not available: see fulltext.
Measurement of t(t)over-bar normalised multi-differential cross sections in pp collisions at root s=13 TeV, and simultaneous determination of the strong coupling strength, top quark pole mass, and parton distribution functions
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdalla Hassan
- Abdullin Salavat
- Abercrombie Daniel
- Acharya Himal
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Aggleton Robin
- Agram Jean-Laurent
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmad Muhammad
- Ahuja Sudha
- Akbiyik Melike
- Akchurin Nural
- Akgun Bora
- Al-bataineh Ayman
- Albajar Carmen
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Allen Brandon
- Almond John
- Alverson George
- Alves Fábio Lúcio
- Alves Gilvan
- Alyari Maral
- Amapane Nicola
- Ambrogi Federico
- Amendola Chiara
- Amin Nick
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Antonelli Louis
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apresyan Artur
- Apyan Aram
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- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
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- Arneodo Michele
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- Smith Dominic
- Smith Geoffrey
- Smith Nicholas
- Smith Vincent J
- Smith Wesley H
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- Spalding William J
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- Tonelli Manganote Edmilson José
- Tonelli Guido
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- Tonon Nicolas
- Tonwar Suresh C
- Torassa Ezio
- Toropin Alexander
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- Yetkin Elif Asli
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- Zaganidis Nicolas
- Zahid Sema
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- Zalewski Piotr
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- Zanetti Marco
- Zarubin Anatoli
- Zarucki Mateusz
- Zeinali Maryam
- Zenaiev Oleksandr
- Zenz Seth Conrad
- Zeuner Wolfram Dietrich
- Zevi Della Porta Giovanni
- Zeyrek Mehmet
- Zghiche Amina
- Zhang Aobo
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Sijing
- Zhang Zhicai
- Zhao Jingzhou
- Zhokin Alexander
- Zhu De Hua
- Zhu Ren-Yuan
- Zientek Margaret
- Zobec Joze
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Álvarez Fernández Adrian
- Özçelik Özlem
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Peer reviewe
An embedding technique to determine ττ backgrounds in proton-proton collision data
- Author
- Aarrestad Thea Klaeboe
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abdulsalam Abdulla
- Abercrombie Daniel
- Acharya Himal
- Ackert Andrew
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adams Mark Raymond
- Adams Todd
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agaras Merve Nazlim
- Aggleton Robin
- Agram Jean-Laurent
- Ahmad Ashfaq
- Ahmad Muhammad, 1
- Ahmad Muhammad, 2
- Ahuja Sudha
- Akbiyik Melike
- Akchurin Nural
- Akgun Bora
- Al-bataineh Ayman
- Albajar Carmen
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Allen Brandon
- Almond John
- Alverson George
- Alves Fábio Lúcio
- Alves Gilvan
- Alyari Maral
- Amapane Nicola
- Ambrogi Federico
- Amendola Chiara
- Amin Nick
- Amsler Claude
- Anagnostou Georgios
- Anderson Dustin
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Antonelli Louis
- Antropov Iurii
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arndt Till
- Arneodo Michele
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asghar Muhammad Irfan
- Asilar Ece
- Askew Andrew
- Atakisi Ismail Okan
- Ather Mohsan Waseem
- Attikis Alexandros
- Auffray Etiennette
- Aushev Tagir
- Autermann Christian
- Auzinger Georg
- Avdeeva Ekaterina
- Avery Paul
- Avila Carlos
- Ayala Edy
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzolini Virginia
- Azzurri Paolo
- Baarmand Marc M
- Babaev Anton
- Babounikau Illia
- Bacchetta Nicola
- Bachiller Irene
- Bachtis Michail
- Backhaus Malte
- Baden Drew
- Bagliesi Giuseppe
- Bahinipati Seema
- Baidali Sergei
- Baillon Paul
- Bainbridge Robert
- Bakas Georgios
- Bakhshiansohi Hamed
- Bakirci Mustafa Numan
- Ball Austin
- Ball Fionn
- Ban Yong
- Band Reyer
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Bargassa Pedrame
- Baringer Philip
- Barker Anthony
- Barnes Virgil E
- Barney David
- Barnyakov Alexander
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- Belchior Batista Das Chagas Ewerton
- Belforte Stefano
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- Bellan Riccardo
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- Belyaev Andrey
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- Delannoy Hugo
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- Zenaiev Oleksandr
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- Zeuner Wolfram Dietrich
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- Zeyrek Mehmet
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- Zhang Aobo
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- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
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- Zuo Xunwu
- Zuolo Davide
- Álvarez Fernández Adrian
- Özçelik Özlem
- Publication venue
- Publication date
- 01/01/2019
- Field of study
An embedding technique is presented to estimate standard model tau tau backgrounds from data with minimal simulation input. In the data, the muons are removed from reconstructed mu mu events and replaced with simulated tau leptons with the same kinematic properties. In this way, a set of hybrid events is obtained that does not rely on simulation except for the decay of the tau leptons. The challenges in describing the underlying event or the production of associated jets in the simulation are avoided. The technique described in this paper was developed for CMS. Its validation and the inherent uncertainties are also discussed. The demonstration of the performance of the technique is based on a sample of proton-proton collisions collected by CMS in 2017 at root s = 13 TeV corresponding to an integrated luminosity of 41.5 fb(-1).Peer reviewe
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