12 research outputs found
Pan-cancer analysis of whole genomes
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- Weisenberger
- Welch
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- wi Futreal
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- Williams
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- Wiznerowicz
- Wolf
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- Xiong
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- xp Benz
- xp Edwards
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- Yau
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- yd Schadendorf
- ye Auman
- ye Umbricht
- Yellapantula
- Yellapantula
- yh Bathe
- yj Baylin
- Yoon
- Yu
- Yu
- Yu
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- Yugawa
- z ah
- Z. ej
- Z. ep
- Z. fr
- Z. hv
- Z. hy
- Z. jq
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- Z. oe
- Zaikova
- Zapatka
- zd Gershenwald
- Zenklusen
- Zeps
- zf Ghossein
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang H. b
- Zhao
- Zheng
- Zhou
- Zhou
- Zhu
- Zhu
- zi zj
- zm Jayaseelan
- Zou
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- zw Lewis
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- Publication date
- 11/12/2019
- Field of study
Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale(1-3). Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4-5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter(4); identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation(5,6); analyses timings and patterns of tumour evolution(7); describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity(8,9); and evaluates a range of more-specialized features of cancer genomes(8,10-18).Peer reviewe
Lignocellulosic Biofuels and Grass Plants Used in Production of Pellets
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- 'Riga Technical University'
- Publication date
- 18/12/2013
- Field of study
Use of plant biomass in energy production is one ofthe preconditions to compensate growing shortage of fossilresources; therefore the research covered production of pelletsamples and testing of quality parameters thereof. The studyaimed at researching hemicellulose indicators in osier and poplarpellets, lignin content in perennial crops (depending on fertilisertypes, norms), parameters characterising pellet contentvariations (their evaluation and optimisation depending upon theproportions of pellet components) as well as characterisation oflignocellulose parameters
Composite anodes for lithium-ion batteries: status and trends
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- 'American Institute of Mathematical Sciences (AIMS)'
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- 01/01/2016
- Field of study
Novel materials for fuel cells operating on liquid fuels
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- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2017
- Field of study
Redox-regulated transcription in plants: Emerging concepts
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- Apel K Hirt H
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The Contribution of Cell Surface Components to the Neutrophil Mechanosensitivity to Shear Stresses
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- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2015
- Field of study
Combination of graphene and graphene oxide with metal and metal oxide nanoparticles in fabrication of electrochemical enzymatic biosensors
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- A Abellán-Llobregat
- A Chen
- A Ciesielski
- A Gupta
- A Iqbal
- AC Ferrari
- AL Henry
- AT Lawal
- B Wang
- C Feng
- C Rao
- C Shan
- C Xue
- C Yang
- C Zhu
- C-T Hsieh
- D Feng
- D Pan
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- E Sadeghinezhad
- EP Cipolatti
- EP Cipolatti
- EP Randviir
- ET Hwang
- FM Fartas
- G Gotti
- G Yang
- G Zhiguo
- H Arjmandi-Tash
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- K Zhou
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- K-J Huang
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- L Polavarapu
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- M Baghayeri
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- M Kapilashrami
- M Madian
- M Nasrollahzadeh
- M Shen
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- M Zhao
- ME Uddin
- ML Yola
- MM Rahman
- N Chauhan
- N Yang
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- NH Kim
- P Das
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- Q Chen
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- Q Xu
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- R Elshafey
- RK Layek
- RS Yadav
- RV Devi
- S Aslan
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- S Goenka
- S Kumar
- S Lepinay
- S Mao
- S Pattnaik
- S Sabury
- S Zhu
- S-H Hwang
- S-J Kim
- SG Leonardi
- SS Varghese
- SZ Butler
- T Gu
- T Palaniselvam
- T Pasang
- TEM Nancy
- TMBF Oliveira
- V Georgakilas
- V Urbanova
- VL Bridewell
- W Putzbach
- W Sun
- X Wang
- X Zan
- Y Fang
- Y Wang
- Y Xin
- Y Zhang
- Y Zhang
- Y Zhou
- Z Lin
- Z Miao
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Information technology adoption: a review of the literature and classification
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- A Al-Adwan
- A Althunibat
- A Aluri
- A Bandura
- A Chong
- A Dickinger
- A Jeyaraj
- A Molla
- A Negahban
- A Neupane
- A Oyedele
- A Rawashdeh
- A Tarhini
- A White
- A Zuiderwijk
- AH Crespo
- AJ Setterstrom
- AM Khasawneh
- AN Tashkandi
- AR Montazemi
- AS Al-Ajam
- AY Chong
- AY-L Chong
- AY-L Chong
- AY-L Chong
- AYL Chong
- B Gupta
- B Hoof
- B Kijsanayotin
- B McKenna
- B Okumus
- B Pynoo
- B Ramdani
- B Vatanasombut
- B Watjatrakul
- BR Clark
- C Buabeng-Andoh
- C Der Chen
- C Jin
- C Kim
- C Kim
- C Lee
- C Martins
- C Wu
- C Xu
- C Yang
- C-C Chang
- C-C Lee
- C-F Chen
- C-H Yen
- C-M Chiu
- C-W Chu
- C-WD Chen
- CC Chen
- CH Hsiao
- CH Lin
- CH Wong
- CS Nam
- CS Yiu
- D Compeau
- D Karaali
- D Kim
- D Kipnis
- D Laux
- D Lee
- D Maditinos
- D Zheng
- D-F Sheu
- D-H Shin
- D-L Huang
- DC Karaiskos
- DC Yen
- DD Gunawan
- DE Zand
- DH Shin
- DH Zhu
- DH Zhu
- DL Goodhue
- DL Goodhue
- E AbuShanab
- E Anderson
- E Lee
- E Lwoga
- E MacLennan
- E Park
- E Park
- E Park
- EC Tupes
- EL Slade
- ET Lwoga
- Examining barriers to health information technology adoption
- F Bélanger
- F Chukwunonso
- F Davis
- F Grove De
- F Hussain Chandio
- F Liébana-Cabanillas
- F Liébana-Cabanillas
- F Yin
- F-C Tung
- FC Tung
- FO Bankole
- G Baptista
- G Hua
- G Mortimer
- G Premkumar
- GB Svendsen
- GC Moore
- GJ Udo
- GJ Udo
- GW-H Tan
- H Amin
- H Dai
- H Gangwar
- H Gangwar
- H Hsin Chang
- H Karjaluoto
- H Mohammadi
- H Tsai
- H Wei
- H Yang
- H-F Lin
- H-F Lin
- H-L Yang
- H-P Lu
- H-P Lu
- H-W Kim
- H-Y Wang
- Halina Mohamed Dahlan
- HJ Mun
- HL Liao
- HL Yang
- HS Tsai
- I Ajzen
- I Ajzen
- I Ajzen
- I Ajzen
- I Asnira
- I Bashir
- I Benbasat
- I Brown
- I Im
- I Reychav
- I Rodríguez-Ardura
- I Sila
- I-L Wu
- ID Constantiou
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- J Kim
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- JE Bigné
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- JK Oostrom
- JL Moreno Cegarra
- JMCJMC Hernandez
- JS Colemen
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- K Amoako-Gyampah
- K Eriksson
- K Johnston
- K Kapoor
- K Mac Callum
- K Magsamen-conrad
- K Rouibah
- K-B Ooi
- KA Al-Busaidi
- KA Jehn
- KK Kapoor
- KL Gwebu
- L Carter
- L Carter
- L Di Pietro
- L Gao
- L Qin
- L Ramanathan
- L Tornatzky
- L Wei
- L Zhang
- L-Y Leong
- LC Schaupp
- LD Booker
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- M Ahmad
- M Akhtar Shareef
- M Alavi
- M Alomari
- M Csikszentmihalyi
- M Csikszentmihalyi
- M Fagan
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- M-C Alarcón-del-Amo
- M-C Lee
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- M-Y Chen
- MA Hossain
- MA Shareef
- Maryam Salahshour Rad
- MD Gallego
- Mehrbakhsh Nilashi
- MJ Brand
- MJ Metzger
- MK Chang
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- ML To
- MM Al-Debei
- MMMA Riffai
- MP Mount
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- MS Featherman
- MZ Lallmahomed
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- N Ahmad
- N Al-Qirim
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- N Mallat
- N Nistor
- N Park
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- N Park
- N Siamagka
- NO Ndubisi
- NP Rana
- O Al-hujran
- OK Lean
- OM Yigitbasioglu
- P Datta
- P Guriting
- P Hanafizadeh
- P Hanafizadeh
- P Hsieh
- P Legris
- P Pai
- P-F Hsu
- Q Cao
- Q Gan
- R Chen
- R Gupta
- R Hussein
- R Peres
- R Ramanathan
- R Rauniar
- R Yadav
- R-Z Kuo
- RH Blake
- RL Oliver
- RL Oliver
- RM Kramer
- RP Bagozzi
- S Agrebi
- S Amaro
- S Basaglia
- S Cheng
- S Goode
- S Kim
- S Kurnia
- S Lee
- S Liang
- S Liao
- S Liu
- S Moghavvemi
- S Mouakket
- S Nikou
- S Oum
- S Ozkan
- S Pan
- S Petter
- S Prompattanapakdee
- S Sang
- S Sintonen
- S Tseng
- S Yang
- S Yang
- S Özkan
- S-Y Cheng
- S-Y Hung
- S-Y Hung
- SA Nasco
- SH Kim
- SMC Loureiro
- SMF Bukhari
- T Casey
- T Che
- T Heart
- T Hong
- T Hopp
- T Lam
- T Oliveira
- T Oliveira
- T Ramayah
- T Schrier
- T Teo
- T Teo
- T Teo
- T Thomas
- T Zarmpou
- T Zhou
- T Zhou
- TC-K Huang
- TD Nguyen
- TE Cheng
- TE Ruggiero
- TJV Saldanha
- TS Behrend
- TTC Lin
- V Ratten
- V Venkatesh
- V Venkatesh
- V Venkatesh
- V Venkatesh
- V Venkatesh
- V Weerakkody
- VA Zeithaml
- VC Gu
- VP Aggelidis
- W Lee
- W Tsai
- W-C Hung
- W-L Shiau
- W-W Wu
- W-W Wu
- WA Al-Ghaith
- WG Kim
- WH DeLone
- WR King
- WW Zhu
- X Luo
- X Tan
- X Tan
- X Wu
- X-L Shen
- Y Alshamaila
- Y Cheng
- Y Gao
- Y Hwang
- Y Jung
- Y Kamarulzaman
- Y Lee
- Y Lee
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- Y Sun
- Y Wang
- Y-C Shen
- Y-F Kuo
- Y-H Lee
- Y-M Cheng
- Y-S Wang
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- YC Chen
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- YP Chang
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- ÁF Agudo-Peregrina
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- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Recent Advances in Biophysical stimulation of MSC for bone regeneration
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- Adamo L Garcia-Carde-AG.
- Alin M Li Z, Stoddart MJ, Yao S-J.
- Angle SR Sena K, Sumner DR, Virdi AS.
- Baker BM Shah RP, Huang AH, Mauck RL.
- Banka S Mukudai Y, Yoshihama Y, Shirota T, Kondo S, Shintani S.
- Bassaneze V Barauna V, Lavini-Ramos C, Kalil J, Schettert I, Miyakawa A.
- Basset C Pawluck R, Becker R.
- Bassett AL Becker RO.
- Bassett C Mitchell S, Gaston S.
- Bassett C Pawluk R, Pilla A.
- Bassett C Pilla A, Pawluk R.
- Baureus Koch CLM Sommarin M, Persson BRR, Salford LG, Eberhardt JL
- Boonrungsiman S Gentleman E, Carzaniga R, Evans ND, Mccomb DW.
- Buschmann MD Kim Y, Wong M, Frank E, Hunziker EB, Grodzinsky AJ.
- Carroll SF Buckley CT, Kelly DJ.
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- Publication venue
- 'Indian Society for Education and Environment'
- Publication date
- Field of study
Recent Advances in Biophysical stimulation of MSC for bone regeneration
- Author
- Adamo L Garcia-Carde-AG.
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- Charoenpanich A Wall ME, Tucker CJ, Andrews DMK, Lalush DS, Dirschl DR.
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- Publication venue
- 'Indian Society for Education and Environment'
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