Organizational Climate and Commitment: A Case Study of an Urban Nonprofit Organization

This qualitative study investigates the relationship between the two constructs: Organizational Climate and Organizational Commitment. Litwin and Stringer (1968) suggested that a molar model is needed to explain employee behavior and motivation. Climate was proposed as this molar construct. Research concerning Organizational Climate resulted in multiple definitions and little consensus concerning the number and use of multiple dimensions of this construct. The almost exclusive use of survey methods coupled with methodological confusion with Organizational Culture created difficulty with the use of this important construct. Organizational Commitment research resulted in a number of competing definitions. Research by Meyer and Allen (1997) eventually led to continuance, normative, and affective commitment as a three-component model of Organizational Commitment. Despite suggestions in the literature, little research has been conducted explaining how Organizational Climate and Organizational Commitment constructs relate. The study is composed of a pencil and paper survey. Indexes of the nine components of Organizational Climate based on McNabb and Sepic\u27s (1995) definitions were correlated with the three components of Organizational Commitment based on Meyer and Allen\u27s (1997) definitions. Focus group meetings and individual interviews were held to investigate worker understandings of both constructs. Open coding was used to identify themes from the interviews. This methodological triangulation within an instrumental case study resulted in findings of relationship between the two constructs by the application of each of the three methodologies. Survey results showed correlations between seven of the nine Organizational Climate dimensions and two of the components of Organizational Commitment. However, continuous commitment showed no correlations with any Organizational Climate dimension. Focus group and individual interviews indicated that workers perceive that a relationship between the two constructs definitely exists. Findings from this study suggest a more extensive molar model than proposed by Litwin and Stringer (1968). Recommendations for nonprofit policy and practice are suggested. Future research in six areas is identified to expand this case study of an urban private nonprofit organization

A Systems Approach to Dissecting Immune Gene Regulatory Networks in the Modulation of Brain Function

Although the central nervous system was long perceived as the ivory tower without immune entities, there is growing evidence that the immune and nervous systems are intimated connected. These two systems have been shown to communicate both cellularly and molecularly under physiological and pathological conditions. Despite our increasing understanding of the interplay between these two systems, there are still numerous open questions. In this thesis, I address such unanswered questions related to: the role of microglia and their mechanism in contributing to pathologies in Rett syndrome; the beneficial effects of T-cell secreted cytokines in supporting social brain function; the evolutionary link of the interactions between the nervous and immune systems; the transcription regulation of a subset of microglia population in common neurodegenerative diseases. Collectively, the current thesis is focused on the joint frontier of bioinformatics and experimental work in neuroimmunology. A multifaceted approach, that includes transcriptomics, genomics and other biomolecular modules, was implemented to unearth signaling pathways and mechanisms underlying the presenting biological phenomena. The findings of this thesis can be summarized as follows: 1) MeCP2 acts as a master regulator in the transcriptional repression of inflammatory stimuli in macrophages; 2) T-cell secreted IFN-γ supports social brain function through an evolutionally conserved interaction between the immune and nervous systems; 3) The APOE-TREM2 pathway regulates the microglia phenotype switch in neurodegenerative diseases. Provided that recent technologies allow for readily manipulating the immune system, the findings presented herein may create new vistas for therapeutic interventions in various neurological disorders

Exogenous double-stranded RNA inhibits the infection physiology of rust fungi to reduce symptoms in planta

Rust fungi (Pucciniales) are a diverse group of plant pathogens in natural and agricultural systems. They pose ongoing threats to the diversity of native flora and cause annual crop yield losses. Agricultural rusts are predominantly managed with fungicides and breeding for resistance, but new control strategies are needed on non-agricultural plants and in fragile ecosystems. RNA interference (RNAi) induced by exogenous double-stranded RNA (dsRNA) has promise as a sustainable approach for managing plant-pathogenic fungi, including rust fungi. We investigated the mechanisms and impact of exogenous dsRNA on rust fungi through in vitro and whole-plant assays using two species as models, Austropuccinia psidii (the cause of myrtle rust) and Coleosporium plumeriae (the cause of frangipani rust). In vitro, dsRNA either associates externally or is internalized by urediniospores during the early stages of germination. The impact of dsRNA on rust infection architecture was examined on artificial leaf surfaces. dsRNA targeting predicted essential genes significantly reduced germination and inhibited development of infection structures, namely appressoria and penetration pegs. Exogenous dsRNA sprayed onto 1-year-old trees significantly reduced myrtle rust symptoms. Furthermore, we used comparative genomics to assess the wide-scale amenability of dsRNA to control rust fungi. We sequenced genomes of six species of rust fungi, including three new families (Araucariomyceaceae, Phragmidiaceae, and Skierkaceae) and identified key genes of the RNAi pathway across 15 species in eight families of Pucciniales. Together, these findings indicate that dsRNA targeting essential genes has potential for broad-use management of rust fungi across natural and agricultural systems

Comparison of instructor-led versus peer-led debriefing in nursing students

Despite its widespread support, the most effective simulation-based debriefing method has little evidence to support its efficacy. In this study, we compared the effect of peer-led and instructor-led debriefing among nursing students. The study was conducted with a non-equivalent control group using a pretest-post-test design. A convenience sample of third-year nursing students was used for the study, where 65 students enrolled in a 2-week clinical placement rotation were randomly assigned to the instructor-led group or peer-led group. The quality of cardiopulmonary resuscitation skills, satisfaction with simulation, and quality of debriefing in the peer-led group were compared to those in the instructor-led group. Group differences at each testing interval were analyzed using independent t-test. Nursing students in the instructor-led debriefing group showed better subsequent cardiopulmonary resuscitation performance, more satisfaction with simulation experience, and higher debriefing scores compared to the peer-led group. From our study, instructor-led debriefing is an effective method in improving skills performance, inducing favorable satisfaction, and providing better quality of debriefing among nursing students. © 2016 John Wiley & Sons Australia, Ltd

Crustal structure of the ocean-continent transition at Flemish Cap : seismic refraction results

Author Posting. © American Geophysical Union, 2003. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research 108, B11 (2003): 2531, doi:10.1029/2003JB002434.We conducted a seismic refraction experiment across Flemish Cap and into the deep basin east of Newfoundland, Canada, and developed a velocity model for the crust and mantle from forward and inverse modeling of data from 25 ocean bottom seismometers and dense air gun shots. The continental crust at Flemish Cap is 30 km thick and is divided into three layers with P wave velocities of 6.0–6.7 km/s. Across the southeast Flemish Cap margin, the continental crust thins over a 90-km-wide zone to only 1.2 km. The ocean-continent boundary is near the base of Flemish Cap and is marked by a fault between thinned continental crust and 3-km-thick crust with velocities of 4.7–7.0 km/s interpreted as crust from magma-starved oceanic accretion. This thin crust continues seaward for 55 km and thins locally to ~1.5 km. Below a sediment cover (1.9–3.1 km/s), oceanic layer 2 (4.7–4.9 km/s) is ~1.5 km thick, while layer 3 (6.9 km/s) seems to disappear in the thinnest segment of the oceanic crust. At the seawardmost end of the line the crust thickens to ~6 km. Mantle with velocities of 7.6–8.0 km/s underlies both the thin continental and thin oceanic crust in an 80-km-wide zone. A gradual downward increase to normal mantle velocities is interpreted to reflect decreasing degree of serpentinization with depth. Normal mantle velocities of 8.0 km/s are observed ~6 km below basement. There are major differences compared to the conjugate Galicia Bank margin, which has a wide zone of extended continental crust, more faulting, and prominent detachment faults. Crust formed by seafloor spreading appears symmetric, however, with 30-km-wide zones of oceanic crust accreted on both margins beginning about 4.5 m.y. before formation of magnetic anomaly M0 (~118 Ma).This work was supported by National Science Foundation grant OCE 9819053, the Danish Research Foundation (Danmarks Grundforskningsfond), and the Natural Science and Engineering Research Council of Canada. B. Tucholke also acknowledges support by the Henry Bryant Bigelow Chair in Oceanography at Woods Hole Oceanographic Institution

British signals intelligence and the 1916 Easter Rising in Ireland

Historians for decades have placed Room 40, the First World War British naval signals intelligence organization, at the centre of narratives about the British anticipation of and response to the Easter Rising in Ireland in 1916. A series of crucial decrypts of telegrams between the German embassy in Washington and Berlin, it has been believed, provided significant advance intelligence about the Rising before it took place. This article upends previous accounts by demonstrating that Room 40 possessed far less advance knowledge about the Rising than has been believed, with most of the supposedly key decrypts not being generated until months after the Rising had taken place

Writing in Britain and Ireland, c. 400 to c. 800

No abstract available

Working with activity theory : context, technology, and information behavior

Over the last 7 years, the AIMTech Research Group in the University of Leeds has used cultural‐historical activity theory (CHAT) to inform a range of research activities in the fields of information behavior and information systems. In this article, we identify certain openings and theoretical challenges in the field of information behavior, which sparked our initial interest in CHAT: context, technology, and the link between practice and policy. We demonstrate the relevance of CHAT in studying information behavior and addressing the identified openings and argue that by providing a framework and hierarchy of activity‐action‐operation and semantic tools, CHAT is able to overcome many of the uncertainties concerning information behavior research. In particular, CHAT provides researchers a theoretical lens to account for context and activity mediation and, by doing so, can increase the significance of information behavior research to practice. In undertaking this endeavour, we have relied on literature from the fields of information science and others where CHAT is employed. We provide a detailed description of how CHAT may be applied to information behavior and account for the concepts we see as relevant to its study

Multiwavelength studies of MHD waves in the solar chromosphere: An overview of recent results

The chromosphere is a thin layer of the solar atmosphere that bridges the relatively cool photosphere and the intensely heated transition region and corona. Compressible and incompressible waves propagating through the chromosphere can supply significant amounts of energy to the interface region and corona. In recent years an abundance of high-resolution observations from state-of-the-art facilities have provided new and exciting ways of disentangling the characteristics of oscillatory phenomena propagating through the dynamic chromosphere. Coupled with rapid advancements in magnetohydrodynamic wave theory, we are now in an ideal position to thoroughly investigate the role waves play in supplying energy to sustain chromospheric and coronal heating. Here, we review the recent progress made in characterising, categorising and interpreting oscillations manifesting in the solar chromosphere, with an impetus placed on their intrinsic energetics.Comment: 48 pages, 25 figures, accepted into Space Science Review

Echinacea purpurea and osteopathic manipulative treatment in children with recurrent otitis media: a randomized controlled trial

<p>Abstract</p> <p>Background</p> <p>Recurrent otitis media is a common problem in young children. Echinacea and osteopathic manipulative treatment have been proposed as preventive measures, but have been inadequately studied. This study was designed to assess the efficacy of <it>Echinacea purpurea </it>and/or osteopathic manipulative treatment (OMT) for prevention of acute otitis media in otitis-prone children.</p> <p>Methods</p> <p>A randomized, placebo-controlled, two-by-two factorial trial with 6-month follow-up, conducted 1999 – 2002 in Tucson, Arizona. Patients were aged 12–60 months with recurrent otitis media, defined as three or more separate episodes of acute otitis media within six months, or at least four episodes in one year. Ninety children (44% white non-Hispanic, 39% Hispanic, 57% male) were enrolled, of which 84 had follow-up for at least 3 months. Children were randomly assigned to one of four protocol groups: double placebo, echinacea plus sham OMT, true OMT (including cranial manipulation) plus placebo echinacea, or true echinacea plus OMT. An alcohol extract of <it>Echinacea purpurea </it>roots and seeds (or placebo) was administered for 10 days at the first sign of each common cold. Five OMT visits (or sham treatments) were offered over 3 months.</p> <p>Results</p> <p>No interaction was found between echinacea and OMT. Echinacea was associated with a borderline increased risk of having at least one episode of acute otitis media during 6-month follow-up compared to placebo (65% versus 41%; relative risk, 1.59, 95% CI 1.04, 2.42). OMT did not significantly affect risk compared to sham (44% versus 61%; relative risk, 0.72, 95% CI 0.48, 1.10).</p> <p>Conclusion</p> <p>In otitis-prone young children, treating colds with this form of echinacea does not decrease the risk of acute otitis media, and may in fact increase risk. A regimen of up to five osteopathic manipulative treatments does not significantly decrease the risk of acute otitis media.</p> <p>Trial registration</p> <p>ClinicalTrials.gov Identifier: NCT00010465</p