Sudden gains in internet cognitive therapy for social anxiety disorder in routine clinical practice

Background: Sudden gains are large symptom improvements between consecutive therapy sessions. They have been shown to occur in randomised controlled trials of internet-delivered psychological interventions, but little is known about their occurrence when such treatments are delivered in routine clinical practice. Objective: This study examined the occurrence of sudden gains in a therapist-guided internet-delivered Cognitive Therapy intervention for social anxiety disorder (iCT-SAD) delivered in the UK NHS talking therapies for anxiety and depression (formerly known as IAPT services). It aimed to assess whether sudden gains were associated with better therapy outcomes, and examine changes in process variables around the period of sudden gains. Methods: The study examined sudden gains based on the Liebowitz Social Anxiety Scale. Of 193 treated patients, 146 provided sufficient data to permit analysis. Linear mixed effects models were used to examine the impact of sudden gains on clinical outcomes, and examine changes in negative social cognitions, self-focused attention, and depressed mood. Results: Seventy sudden gains were found among 57 participants. The occurrence rate of sudden gains was 39 %. Individuals who experienced sudden gains had a larger reduction in social anxiety symptoms at end of intervention and at three-month follow-up. There was evidence of a reduction in the frequency of negative social cognitions prior to the gain, whereas changes in self-focused attention occurred simultaneously with the gain. Depressed mood did not show significant changes over these timepoints. Conclusions: Approximately 2 in 5 patients experienced a sudden gain whilst accessing the iCT-SAD intervention in routine practice. They were associated with better clinical outcomes following treatment compared to those who did not experience a sudden gain

Landau-Ginzburg Description of Boundary Critical Phenomena in Two Dimensions

The Virasoro minimal models with boundary are described in the Landau-Ginzburg theory by introducing a boundary potential, function of the boundary field value. The ground state field configurations become non-trivial and are found to obey the soliton equations. The conformal invariant boundary conditions are characterized by the reparametrization-invariant data of the boundary potential, that are the number and degeneracies of the stationary points. The boundary renormalization group flows are obtained by varying the boundary potential while keeping the bulk critical: they satisfy new selection rules and correspond to real deformations of the Arnold simple singularities of A_k type. The description of conformal boundary conditions in terms of boundary potential and associated ground state solitons is extended to the N=2 supersymmetric case, finding agreement with the analysis of A-type boundaries by Hori, Iqbal and Vafa.Comment: 42 pages, 13 figure

Gamma-ray and radio tests of the e+e- excess from DM annihilations

PAMELA and ATIC recently reported an excess in e+e- cosmic rays. We show that if it is due to Dark Matter annihilations, the associated gamma-ray flux and the synchrotron emission produced by e+e- in the galactic magnetic field violate HESS and radio observations of the galactic center and HESS observations of dwarf Spheroidals, unless the DM density profile is significantly less steep than the benchmark NFW and Einasto profiles.Comment: 16 pages, 4 figures; v2: normalizations fixed in Table 2 and typos corrected (no changes in the analysis nor the results), some references and comments added; v3: minor additions, matches published versio

Antiproton constraints on dark matter annihilations from internal electroweak bremsstrahlung

If the dark matter particle is a Majorana fermion, annihilations into two fermions and one gauge boson could have, for some choices of the parameters of the model, a non-negligible cross-section. Using a toy model of leptophilic dark matter, we calculate the constraints on the annihilation cross-section into two electrons and one weak gauge boson from the PAMELA measurements of the cosmic antiproton-to-proton flux ratio. Furthermore, we calculate the maximal astrophysical boost factor allowed in the Milky Way under the assumption that the leptophilic dark matter particle is the dominant component of dark matter in our Universe. These constraints constitute very conservative estimates on the boost factor for more realistic models where the dark matter particle also couples to quarks and weak gauge bosons, such as the lightest neutralino which we also analyze for some concrete benchmark points. The limits on the astrophysical boost factors presented here could be used to evaluate the prospects to detect a gamma-ray signal from dark matter annihilations at currently operating IACTs as well as in the projected CTA.Comment: 32 pages; 13 figure

Microcraters in aluminum foils exposed by Stardust

We will present preliminary results on the nature and size frequency distribution of microcraters that formed in aluminum foils during the flyby of comet Wild 2 by the Stardust spacecraft

PPPC 4 DM ID: A Poor Particle Physicist Cookbook for Dark Matter Indirect Detection

We provide ingredients and recipes for computing signals of TeV-scale Dark Matter annihilations and decays in the Galaxy and beyond. For each DM channel, we present the energy spectra of electrons and positrons, antiprotons, antideuterons, gamma rays, neutrinos and antineutrinos e, mu, tau at production, computed by high-statistics simulations. We estimate the Monte Carlo uncertainty by comparing the results yielded by the Pythia and Herwig event generators. We then provide the propagation functions for charged particles in the Galaxy, for several DM distribution profiles and sets of propagation parameters. Propagation of electrons and positrons is performed with an improved semi-analytic method that takes into account position-dependent energy losses in the Milky Way. Using such propagation functions, we compute the energy spectra of electrons and positrons, antiprotons and antideuterons at the location of the Earth. We then present the gamma ray fluxes, both from prompt emission and from Inverse Compton scattering in the galactic halo. Finally, we provide the spectra of extragalactic gamma rays. All results are available in numerical form and ready to be consumed.Comment: 57 pages with many figures and tables. v4: updated to include a 125 higgs boson, computation and discussion of extragalactic spectra corrected, some other typos fixed; all these corrections and updates are reflected on the numerical ingredients available at http://www.marcocirelli.net/PPPC4DMID.html they correspond to Release 2.

Superconductivity in AuNiGe Ohmic contacts to a GaAs-based high mobility two-dimensional electron gas

To cool a high mobility two-dimensional electron gas (2DEG) at a GaAs-AlGaAs heterojunction to milliKelvin temperatures, we have fabricated low resistance Ohmic contacts based on alloys of Au, Ni, and Ge. The Ohmic contacts have a typical contact resistance of R C ≈ 0.8 ω at 4.2 K, which drops to 0.2 ω below 0.9 K. Scanning electron microscope images establish that the contacts have the same inhomogeneous microstructure that has been observed in previous studies. Measurements of the contact resistance R C, the four-terminal resistance along the top of a single contact, and the vertical resistance RV all show that there is a superconductor in the Ohmic contact, which can be turned completely normal with a magnetic field of 0.15 T. We briefly discuss how this superconductivity may be affecting the electrical transport measurements of 2DEGs, especially how it may hinder the cooling of electrons in a 2DEG below 0.1 K