The Maine Annex, vol. 2, no. 11

The Maine Annex begins to discuss the House Committee on Un-American Activities (HCUA), growing fears of private and public citizens suspected of fascist or communist activities, and whether war with Russia was inevitable. The paper also notes the pending presentation about Islam by British Army officer and adventurer Colonel R. V. C. Bodley

The Freshman, vol. 5, no. 18

The Freshman was a weekly, student newsletter issued on Mondays throughout the academic year. The newsletter included calendar notices, coverage of campus social events, lectures, and athletic teams. The intent of the publication was to create unity, a sense of community, and class spirit among first year students

Phloem sap and leaf δ13C, carbohydrates, and amino acid concentrations in Eucalyptus globulus change systematically according to flooding and water deficit treatment

Phloem is a central conduit for the distribution of photoassimilate, nutrients, and signals among plant organs. A revised technique was used to collect phloem sap from small woody plants in order to assess changes in composition induced by water deficit and flooding. Bled phloem sap δ13C and sugar concentrations were compared to δ13C of bulk material, soluble carbon extracts, and the neutral sugar fraction from leaves. Amino acid composition and inorganic ions of the phloem sap was also analysed. Quantitative, systematic changes were detected in phloem sap composition and δ13C in response to altered water availability. Phloem sap δ13C was more sensitive to changes of water availability than the δ13C of bulk leaf, the soluble carbon fraction, and the neutral soluble fraction of leaves. Changes in water availability also resulted in significant changes in phloem sugar (sucrose and raffinose), inorganic nutrient (potassium), and amino acid (phenylalanine) concentrations with important implications for the maintenance of phloem function and biomass partitioning. The differences in carbohydrate and amino acid composition as well as the δ13C in the phloem, along with a new model system for phloem research, offer an improved understanding of the phloem-mediated signal, nutrient, and photoassimilate transduction in relation to water availability

Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci.

We report full-length draft de novo genome assemblies for 16 widely used inbred mouse strains and find extensive strain-specific haplotype variation. We identify and characterize 2,567 regions on the current mouse reference genome exhibiting the greatest sequence diversity. These regions are enriched for genes involved in pathogen defence and immunity and exhibit enrichment of transposable elements and signatures of recent retrotransposition events. Combinations of alleles and genes unique to an individual strain are commonly observed at these loci, reflecting distinct strain phenotypes. We used these genomes to improve the mouse reference genome, resulting in the completion of 10 new gene structures. Also, 62 new coding loci were added to the reference genome annotation. These genomes identified a large, previously unannotated, gene (Efcab3-like) encoding 5,874 amino acids. Mutant Efcab3-like mice display anomalies in multiple brain regions, suggesting a possible role for this gene in the regulation of brain development

ORIENTATION DEPENDENT MECHANICAL PROPERTIES OF 3D PRINTED POLYMER MATRIX COMPOSITES

The use of composite materials for 3D printing is a promising area of study that is largely under-researched. Traditionally manufactured composites are known to have superior mechanical qualities, yet characteristics of 3D printed composite materials are not well documented. In this study, polylactic acid composite filaments with both bronze and stainless-steel reinforcements were characterized using optical microscopy, X-ray powder diffraction, energy dispersive X-ray spectrometry, scanning electron microscope, and nanoindentation to determine reinforcement concentration and elemental composition of the filaments. Samples of each composite were printed with a fused deposition modeling 3D printer for compression and tensile testing in accordance with ASTM standards. Specimens with varying print patterns, build directions, and layer heights were tested to determine the efficacy of each material reinforcement and the effect these user-defined parameters have on the overall mechanical characteristics of the composite. Samples were subjected to 500 hours of accelerated weathering according to ASTM standards. Degradation was due largely to the ultraviolet exposure of the test, and the metallic reinforcements showed reduced crystallinity and resistance to physical deformation. This research provides the Navy and Department of Defense with qualitative data to determine the applicably of 3D printed parts for use in structural and load-bearing components onboard submarines.Lieutenant, United States NavyApproved for public release. Distribution is unlimited

Thigh-length compression stockings and DVT after stroke

Controversy exists as to whether neoadjuvant chemotherapy improves survival in patients with invasive bladder cancer, despite randomised controlled trials of more than 3000 patients. We undertook a systematic review and meta-analysis to assess the effect of such treatment on survival in patients with this disease