Bielefeld University

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    On Kleinian mock modular forms

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    Alfes-Neumann C, Mertens M. On Kleinian mock modular forms. Research in the Mathematical Sciences. 2024.We give an explicit and computationally efficient construction of harmonic weak Maass forms which map to weight 22 newforms under the ξ\xi-operator. Our work uses a new non-analytic completion of the Kleinian ζ\zeta-function from the theory of Abelian functions

    Das unternehmerische Selbst in der Krise

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    Groß E, Hövermann A, Nickel A. Das unternehmerische Selbst in der Krise. Makronom. Debattenreihe „Aspekte der Grenzen“ hrsg. Economists for Future. . 2024.Angesichts der momentan Mehrfachkrisen gerät das lange Zeit dominierende neoliberale Gesellschaftsprogramm an seine Grenzen – und mit ihm seine konstitutiven Leitbilder. Daraus erwachsen demokratiezersetzenden und autoritäre Bewegungen

    Stigma als größte Barriere für gleichberechtigte Teilhabe?

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    Bergdolt J, Strathmeier M, Dehn L. Stigma als größte Barriere für gleichberechtigte Teilhabe? . Soziale Psychiatrie . 2024;1:49-52

    Atomic structure and water arrangement on K-feldspar microcline (001)

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    Dickbreder T, Sabath F, Reischl B, et al. Atomic structure and water arrangement on K-feldspar microcline (001). Nanoscale. 2024.The properties of clouds, such as their reflectivity or their likelihood to precipitate, depend on whether the cloud droplets are liquid or frozen. Thus, understanding the ice nucleation mechanisms is essential for the development of reliable climate models. Most ice nucleation in the atmosphere is heterogeneous, i.e., caused by ice nucleating particles such as mineral dusts or organic aerosols. In this regard, K-feldspar minerals have attracted great interest recently as they have been identified as one of the most important ice nucleating particles under mixed-phase cloud conditions. The mechanism by which feldspar minerals facilitate ice nucleation remains, however, elusive. Here, we present atomic force microscopy (AFM) experiments on microcline (001) performed in an ultrahigh vacuum and at the solid-water interface together with density functional theory (DFT) and molecular dynamics (MD) calculations. Our ultrahigh vacuum data reveal features consistent with a hydroxyl-terminated surface. This finding suggests that water in the residual gas readily reacts with the surface. Indeed, the corresponding DFT calculations confirm a dissociative water adsorption. Three-dimensional AFM measurements performed at the mineral-water interface unravel a layered hydration structure with two features per surface unit cell. A comparison with MD calculations suggests that the structure observed in AFM corresponds to the second hydration layer rather than the first water layer. In agreement with previous computation results, no ice-like structure is seen, questioning an explanation of the ice nucleation ability by lattice match. Our results provide an atomic-scale benchmark for the clean and water-covered microcline (001) plane, which is mandatory for understanding the ice nucleation mechanism on feldspar minerals

    Contrasting Explanations in Machine Learning. Efficiency, Robustness & Applications

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    Artelt A. Contrasting Explanations in Machine Learning. Efficiency, Robustness & Applications. Bielefeld: Universität Bielefeld; 2024

    Enhanced protein secretion in reduced genome strains of Streptomyces lividans

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    Hamed MB, Busche T, Simoens K, et al. Enhanced protein secretion in reduced genome strains of Streptomyces lividans. Microbial Cell Factories . 2024;23(1): 13.BACKGROUND: S. lividans TK24 is a popular host for the production of small molecules and the secretion of heterologous protein. Within its large genome, twenty-nine non-essential clusters direct the biosynthesis of secondary metabolites. We had previously constructed ten chassis strains, carrying deletions in various combinations of specialized metabolites biosynthetic clusters, such as those of the blue actinorhodin (act), the calcium-dependent antibiotic (cda), the undecylprodigiosin (red), the coelimycin A (cpk) and the melanin (mel) clusters, as well as the genes hrdD, encoding a non-essential sigma factor, and matAB, a locus affecting mycelial aggregation. Genome reduction was aimed at reducing carbon flow toward specialized metabolite biosynthesis to optimize the production of secreted heterologous protein.; RESULTS: Two of these S. lividans TK24 derived chassis strains showed~15% reduction in biomass yield, 2-fold increase of their total native secretome mass yield and enhanced abundance of several secreted proteins compared to the parental strain. RNAseq and proteomic analysis of the secretome suggested that genome reduction led to cell wall and oxidative stresses and was accompanied by the up-regulation of secretory chaperones and of secDF, a Sec-pathway component. Interestingly, the amount of the secreted heterologous proteins mRFP and mTNFalpha, by one of these strains, was 12 and 70% higher, respectively, than that secreted by the parental strain.; CONCLUSION: The current study described a strategy to construct chassis strains with enhanced secretory abilities and proposed a model linking the deletion of specialized metabolite biosynthetic clusters to improved production of secreted heterologous proteins. © 2023. The Author(s)

    Dataset for "Lee-Yang and Langer edge singularities from analytic continuation of scaling functions"

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    Schmidt-Sonntag C, Karsch F, Singh S. Dataset for "Lee-Yang and Langer edge singularities from analytic continuation of scaling functions". Bielefeld University; 2024.This data set contains all necessary data to reproduce plots in the publication "Lee-Yang and Langer edge singularities from analytic continuation of scaling functions", to be publisched in Phys. Rev. D, 2024 [arXiv:2311.13530[hep-lat]]. The plot scripts are are also included

    A review of stimuli-responsive polymer-based gating membranes

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    Uredat S, Gujare A, Runge J, Truzzolillo D, Oberdisse J, Hellweg T. A review of stimuli-responsive polymer-based gating membranes. Physical Chemistry Chemical Physics. 2024.The formation and properties of smart (stimuli-responsive) membranes are reviewed, with a special focus on temperature and pH triggering of gating to water, ions, polymers, nanoparticles, or other molecules of interest.The formation and properties of smart (stimuli-responsive) membranes are reviewed, with a special focus on temperature and pH triggering of gating to water, ions, polymers, nanoparticles, or other molecules of interest. The review is organized in two parts, starting with all-smart membranes based on intrinsically smart materials, in particular of the poly(N-isopropylacrylamide) family and similar polymers. The key steps of membrane fabrication are discussed, namely the deposition into thin films, functionalization of pores, and the secondary crosslinking of pre-existing microgel particles into membranes. The latter may be free-standing and do not necessitate the presence of a porous support layer. The temperature-dependent swelling properties of polymers provide a means of controlling the size of pores, and thus size-sensitive gating. Throughout the review, we highlight “positive” (gates open) or “negative” (closed) gating effects with respect to increasing temperature. In the second part, the functionalization of porous organic or inorganic membranes of various origins by either microgel particles or linear polymer brushes is discussed. In this case, the key steps are the adsorption or grafting mechanisms. Finally, whenever provided by the authors, the suitability of smart gating membranes for specific applications is highlighted

    Are Robots' Gestures Understood? A Study on the Factors Influencing how Humans Perceive Information Present in Robot Gestures. Perception and integration of robot gestures

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    Bohnenkamp LM, Abramov O, Kopp S. Are Robots' Gestures Understood? A Study on the Factors Influencing how Humans Perceive Information Present in Robot Gestures. Perception and integration of robot gestures. In: HRI Late-Breaking Report . ACM Digital Library; Accepted.Social robots become increasingly important in various social domains like healthcare, education, and industry. In this paper, we explore whether humans understand the meaning conveyed by robot gestures when they occur alongside speech and other co-speech gestures with no meaning. We analyzed human comprehension of basic shapes presented through robot gestures varying gesture size and verbal context. Our findings show that humans notice robot gestures but struggle to understand the information provided by them. Explicitly directing attention to robot gestures improves understanding. Moreover, providing indirect information about robot's capabilities to gesture enhances the human ability to extract the correct information from gestures, with the effect linearly increasing with the number of observations of the robot

    Taking the moral high ground: Deontological and absolutist moral dilemma judgments convey self-righteousness

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    Weiss A, Burgmer P, Rom SC, Conway P. Taking the moral high ground: Deontological and absolutist moral dilemma judgments convey self-righteousness. Journal of Experimental Social Psychology. 2024;110: 104505.Individuals who reject sacrificial harm to maximize overall outcomes, consistent with deontological (vs. utilitarian) ethics, appear warmer, more moral, and more trustworthy. Yet, deontological judgments may not only convey emotional reactions, but also strict adherence to moral rules. We therefore hypothesized that people view deontologists as more morally absolutist and hence self-righteous-as perceiving themselves as morally superior. In addition, both deontologists and utilitarians who base their decisions on rules (vs. emotions) should appear more self-righteous. Four studies (N = 1254) tested these hypotheses. Participants perceived targets as more selfrighteous when they rejected (vs. accepted) sacrificial harm in classic moral dilemmas where harm maximizes outcomes (i.e., deontological vs. utilitarian judgments), but not parallel cases where harm fails to maximize outcomes (Study 1). Preregistered Study 2 replicated the focal effect, additionally indicating mediation via perceptions of moral absolutism. Study 3 found that targets who reported basing their deontological judgments on rules, compared to emotional reactions or when processing information was absent, appeared particularly self-righteous. Preregistered Study 4 included both deontological and utilitarian targets and manipulated whether their judgments were based on rules versus emotion (specifically sadness). Grounding either moral position in rules conveyed self-righteousness, while communicating emotions was a remedy. Furthermore, participants perceived targets as more self-righteous the more targets deviated from their own moral beliefs. Studies 3 and 4 additionally examined participants' self-disclosure intentions. In sum, deontological dilemma judgments may convey an absolutist, rule-focused view of morality, but any judgment stemming from rules (in contrast to sadness) promotes self-righteousness perceptions

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    Publications at Bielefeld University is based in Germany
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