Remote Monitor Alarm System

A remote monitor alarm system monitors discrete alarm and analog power supply voltage conditions at remotely located communications terminal equipment. A central monitoring unit (CMU) is connected via serial data links to each of a plurality of remote terminal units (RTUS) that monitor the alarm and power supply conditions of the remote terminal equipment. Each RTU can monitor and store condition information of both discrete alarm points and analog power supply voltage points in its associated communications terminal equipment. The stored alarm information is periodically transmitted to the CMU in response to sequential polling of the RTUS. The number of monitored alarm inputs and permissible voltage ranges for the analog inputs can be remotely configured at the CMU and downloaded into programmable memory at each RTU. The CMU includes a video display, a hard disk memory, a line printer and an audio alarm for communicating and storing the alarm information received from each RTU

A Genome Scan for Positive Selection in Thoroughbred Horses

Thoroughbred horses have been selected for exceptional racing performance resulting in system-wide structural and functional adaptations contributing to elite athletic phenotypes. Because selection has been recent and intense in a closed population that stems from a small number of founder animals Thoroughbreds represent a unique population within which to identify genomic contributions to exercise-related traits. Employing a population genetics-based hitchhiking mapping approach we performed a genome scan using 394 autosomal and X chromosome microsatellite loci and identified positively selected loci in the extreme tail-ends of the empirical distributions for (1) deviations from expected heterozygosity (Ewens-Watterson test) in Thoroughbred (n = 112) and (2) global differentiation among four geographically diverse horse populations (FST). We found positively selected genomic regions in Thoroughbred enriched for phosphoinositide-mediated signalling (3.2-fold enrichment; P<0.01), insulin receptor signalling (5.0-fold enrichment; P<0.01) and lipid transport (2.2-fold enrichment; P<0.05) genes. We found a significant overrepresentation of sarcoglycan complex (11.1-fold enrichment; P<0.05) and focal adhesion pathway (1.9-fold enrichment; P<0.01) genes highlighting the role for muscle strength and integrity in the Thoroughbred athletic phenotype. We report for the first time candidate athletic-performance genes within regions targeted by selection in Thoroughbred horses that are principally responsible for fatty acid oxidation, increased insulin sensitivity and muscle strength: ACSS1 (acyl-CoA synthetase short-chain family member 1), ACTA1 (actin, alpha 1, skeletal muscle), ACTN2 (actinin, alpha 2), ADHFE1 (alcohol dehydrogenase, iron containing, 1), MTFR1 (mitochondrial fission regulator 1), PDK4 (pyruvate dehydrogenase kinase, isozyme 4) and TNC (tenascin C). Understanding the genetic basis for exercise adaptation will be crucial for the identification of genes within the complex molecular networks underlying obesity and its consequential pathologies, such as type 2 diabetes. Therefore, we propose Thoroughbred as a novel in vivo large animal model for understanding molecular protection against metabolic disease

Supplement: "Localization and broadband follow-up of the gravitational-wave transient GW150914" (2016, ApJL, 826, L13)

This Supplement provides supporting material for Abbott et al. (2016a). We briefly summarize past electromagnetic (EM) follow-up efforts as well as the organization and policy of the current EM follow-up program. We compare the four probability sky maps produced for the gravitational-wave transient GW150914, and provide additional details of the EM follow-up observations that were performed in the different bands

Localization and broadband follow-up of the gravitational-wave transient GW150914

A gravitational-wave (GW) transient was identified in data recorded by the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO) detectors on 2015 September 14. The event, initially designated G184098 and later given the name GW150914, is described in detail elsewhere. By prior arrangement, preliminary estimates of the time, significance, and sky location of the event were shared with 63 teams of observers covering radio, optical, near-infrared, X-ray, and gamma-ray wavelengths with ground- and space-based facilities. In this Letter we describe the low-latency analysis of the GW data and present the sky localization of the first observed compact binary merger. We summarize the follow-up observations reported by 25 teams via private Gamma-ray Coordinates Network circulars, giving an overview of the participating facilities, the GW sky localization coverage, the timeline, and depth of the observations. As this event turned out to be a binary black hole merger, there is little expectation of a detectable electromagnetic (EM) signature. Nevertheless, this first broadband campaign to search for a counterpart of an Advanced LIGO source represents a milestone and highlights the broad capabilities of the transient astronomy community and the observing strategies that have been developed to pursue neutron star binary merger events. Detailed investigations of the EM data and results of the EM follow-up campaign are being disseminated in papers by the individual teams

Localization and Broadband Follow-up of the Gravitational-wave Transient GW150914

A gravitational-wave (GW) transient was identified in data recorded by the Advanced Laser Interferometer Gravitational-wave Observatory (LIGO) detectors on 2015 September 14. The event, initially designated G184098 and later given the name GW150914, is described in detail elsewhere. By prior arrangement, preliminary estimates of the time, significance, and sky location of the event were shared with 63 teams of observers covering radio, optical, near-infrared, X-ray, and gamma-ray wavelengths with ground- and space-based facilities. In this Letter we describe the low-latency analysis of the GW data and present the sky localization of the first observed compact binary merger. We summarize the follow-up observations reported by 25 teams via private Gamma-ray Coordinates Network circulars, giving an overview of the participating facilities, the GW sky localization coverage, the timeline, and depth of the observations. As this event turned out to be a binary black hole merger, there is little expectation of a detectable electromagnetic (EM) signature. Nevertheless, this first broadband campaign to search for a counterpart of an Advanced LIGO source represents a milestone and highlights the broad capabilities of the transient astronomy community and the observing strategies that have been developed to pursue neutron star binary merger events. Detailed investigations of the EM data and results of the EM follow-up campaign are being disseminated in papers by the individual teams. </p

Localization and broadband follow-up of the gravitational-wave transient GW150914

A gravitational-wave transient was identified in data recorded by the Advanced LIGO detectors on 2015 September 14. The event candidate, initially designated G184098 and later given the name GW150914, is described in detail elsewhere. By prior arrangement, preliminary estimates of the time, significance, and sky location of the event were shared with 63 teams of observers covering radio, optical, near-infrared, X-ray, and gamma-ray wavelengths with ground- and space-based facilities. In this Letter we describe the low-latency analysis of the gravitational wave data and present the sky localization of the first observed compact binary merger. We summarize the follow-up observations reported by 25 teams via private Gamma-ray Coordinates Network Circulars, giving an overview of the participating facilities, the gravitational wave sky localization coverage, the timeline and depth of the observations. As this event turned out to be a binary black hole merger, there is little expectation of a detectable electromagnetic signature. Nevertheless, this first broadband campaign to search for a counterpart of an Advanced LIGO source represents a milestone and highlights the broad capabilities of the transient astronomy community and the observing strategies that have been developed to pursue neutron star binary merger events. Detailed investigations of the electromagnetic data and results of the electromagnetic follow-up campaign will be disseminated in the papers of the individual teams

Thigh-length compression stockings and DVT after stroke

Controversy exists as to whether neoadjuvant chemotherapy improves survival in patients with invasive bladder cancer, despite randomised controlled trials of more than 3000 patients. We undertook a systematic review and meta-analysis to assess the effect of such treatment on survival in patients with this disease

Review of Culture and Cultivation in Early Modern England:Writing and the Land, by Michael Leslie and Timothy Raylor; Death and the...

Title full: Review of Culture and Cultivation in Early Modern England: Writing and the Land, by Michael Leslie and Timothy Raylor; Death and the Metropolis: Studies in the Demographic History of London 1670-1830, by John Landers; Capitalism, Culture and Decline in Britain, 1750-1990, by W. D. Rubinstein; Subverting Scotland's Past: Scottish Whig Historians and the Creation of an Anglo-British Identity, 1689-c.1830, by Colin Kidd; Outsiders: Class, Gender and Nation, by Dorothy Thompson; Land and Economy in Baroque Italy: Valpolicella, 1630-1797, by Peter Musgrave; The Seduction of the Mediterranean: Writing, Art, and Homosexual Fantasy, by Robert Aldrich; Geographical Inquiry and American Historical Problems, by Carville Earle; Historical Atlas of Canada, Vol. II: The Land Transformed, 1880-1891, by R. Louis Gentilcore; In the Absence of Towns: Settlement and Country Trade in Southside Virginia, 1730-1800, by Charles J. Farmer; North American Cattle-Ranching Frontiers: Origins, Diffusion, and Differentiation, by Terry G. Jordan; From Wooden Ploughs to Welfare: Why Indian Policy Failed in the Prairie Provinces, by Helen Buckley; Russian Refuge: Religion, Migration, and Settlement on the North American Pacific Rim, by Susan Wiley Hardwick; La Paz de Dios y del Rey: la Conquista de la Selva Lacandona, 1525-1821. Oro Verde: la Conquista de la Selva Lacandona por los Maderos Tabasqueños, 1822-1949, by Jan de Vos; Haciendas and 'Ayllus': Rural Society in the Bolivian Andes in the Eighteenth and Nineteenth Centuries, by Herbert S. Klein; Ideology and Landscape in Historical Perspective: Essays on the Meanings of Some Places in the Past, by A. R.H. Baker and G. Bilger; The Early Modern World-System in Georgraphical Perspectie, by Hans-Jurgen Nitz; European Expansion and Migration: Essays on the Intercontinental Migration from Africa, Asia and Europe, by P. C. Emmer and M. Mörner; Mass Migration in Europe: The Legacy and the Future, by3: Southeast Asia; Book 4: East Asia, by Donald F. Lach and Edwin J. Van Kley; The Remaking of Istanbul: Portrait of an Ottoman City in the Nineteenth Century, by Zeynep Çelik; The Shona and Their Neighbours, by David Beach and Imperial Eyes: Travel Writing and Transculturation, by Mary Louise Pratt.</p

Review of Culture and Cultivation in Early Modern England:Writing and the Land, by Michael Leslie and Timothy Raylor; Death and the...

Title full: Review of Culture and Cultivation in Early Modern England: Writing and the Land, by Michael Leslie and Timothy Raylor; Death and the Metropolis: Studies in the Demographic History of London 1670-1830, by John Landers; Capitalism, Culture and Decline in Britain, 1750-1990, by W. D. Rubinstein; Subverting Scotland's Past: Scottish Whig Historians and the Creation of an Anglo-British Identity, 1689-c.1830, by Colin Kidd; Outsiders: Class, Gender and Nation, by Dorothy Thompson; Land and Economy in Baroque Italy: Valpolicella, 1630-1797, by Peter Musgrave; The Seduction of the Mediterranean: Writing, Art, and Homosexual Fantasy, by Robert Aldrich; Geographical Inquiry and American Historical Problems, by Carville Earle; Historical Atlas of Canada, Vol. II: The Land Transformed, 1880-1891, by R. Louis Gentilcore; In the Absence of Towns: Settlement and Country Trade in Southside Virginia, 1730-1800, by Charles J. Farmer; North American Cattle-Ranching Frontiers: Origins, Diffusion, and Differentiation, by Terry G. Jordan; From Wooden Ploughs to Welfare: Why Indian Policy Failed in the Prairie Provinces, by Helen Buckley; Russian Refuge: Religion, Migration, and Settlement on the North American Pacific Rim, by Susan Wiley Hardwick; La Paz de Dios y del Rey: la Conquista de la Selva Lacandona, 1525-1821. Oro Verde: la Conquista de la Selva Lacandona por los Maderos Tabasqueños, 1822-1949, by Jan de Vos; Haciendas and 'Ayllus': Rural Society in the Bolivian Andes in the Eighteenth and Nineteenth Centuries, by Herbert S. Klein; Ideology and Landscape in Historical Perspective: Essays on the Meanings of Some Places in the Past, by A. R.H. Baker and G. Bilger; The Early Modern World-System in Georgraphical Perspectie, by Hans-Jurgen Nitz; European Expansion and Migration: Essays on the Intercontinental Migration from Africa, Asia and Europe, by P. C. Emmer and M. Mörner; Mass Migration in Europe: The Legacy and the Future, by3: Southeast Asia; Book 4: East Asia, by Donald F. Lach and Edwin J. Van Kley; The Remaking of Istanbul: Portrait of an Ottoman City in the Nineteenth Century, by Zeynep Çelik; The Shona and Their Neighbours, by David Beach and Imperial Eyes: Travel Writing and Transculturation, by Mary Louise Pratt.</p