497 research outputs found

    A CsI(Tl) Scintillating Crystal Detector for the Studies of Low Energy Neutrino Interactions

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    Scintillating crystal detector may offer some potential advantages in the low-energy, low-background experiments. A 500 kg CsI(Tl) detector to be placed near the core of Nuclear Power Station II in Taiwan is being constructed for the studies of electron-neutrino scatterings and other keV-MeV range neutrino interactions. The motivations of this detector approach, the physics to be addressed, the basic experimental design, and the characteristic performance of prototype modules are described. The expected background channels and their experimental handles are discussed.Comment: 34 pages, 11 figures, submitted to Nucl. Instrum. Method

    Еволюція рослинного світу в природному і культигенному середовищі

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    У ході засідань Міжнародної наукової конференції “Еволюція рослинного світу в природному і культигенному середовищі”, присвяченої 200-річчю від Дня народження Чарльза Дарвіна, обговорено актуальні питання еволюційної теорії, ботаніки, фізіології рослин, інтродукції, генетики й селекції, екології, збереження і примноження глобального та локального біорізноманіття, лісових культур і фітомеліорації та інших біологічних наук.В ходе заседаний Международной научной конференции “Эволюция растительного мира в естественной и культигенной среде”, посвященной 200-летию со дня рождения Чарльза Дарвина, обсуждены актуальные вопросы эволюционной теории, ботаники, физиологии растений, интродукции, генетики и селекции, экологии, сохранения и приумножения глобального и локального биоразнообразия, лесных культур и фитомелиорации и других биологических наук.During meetings of the International scientific conference “Evolution of the natural and cultivated plants” to devoted a 200-year from the day of birth of Charles Darwin topical problems of the evolutional theory are discussed, including botany, physiology of plants, introduction of plants, genetics and breeding of plants, ecology, preventing the loss of global and loca biodiversity, arboriculture, forest-growing and other biological sciences

    Measurement of the Bottom-Strange Meson Mixing Phase in the Full CDF Data Set

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    We report a measurement of the bottom-strange meson mixing phase \beta_s using the time evolution of B0_s -> J/\psi (->\mu+\mu-) \phi (-> K+ K-) decays in which the quark-flavor content of the bottom-strange meson is identified at production. This measurement uses the full data set of proton-antiproton collisions at sqrt(s)= 1.96 TeV collected by the Collider Detector experiment at the Fermilab Tevatron, corresponding to 9.6 fb-1 of integrated luminosity. We report confidence regions in the two-dimensional space of \beta_s and the B0_s decay-width difference \Delta\Gamma_s, and measure \beta_s in [-\pi/2, -1.51] U [-0.06, 0.30] U [1.26, \pi/2] at the 68% confidence level, in agreement with the standard model expectation. Assuming the standard model value of \beta_s, we also determine \Delta\Gamma_s = 0.068 +- 0.026 (stat) +- 0.009 (syst) ps-1 and the mean B0_s lifetime, \tau_s = 1.528 +- 0.019 (stat) +- 0.009 (syst) ps, which are consistent and competitive with determinations by other experiments.Comment: 8 pages, 2 figures, Phys. Rev. Lett 109, 171802 (2012

    Isometric Sliced Inverse Regression for Nonlinear Manifolds Learning

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    [[abstract]]Sliced inverse regression (SIR) was developed to find effective linear dimension-reduction directions for exploring the intrinsic structure of the high-dimensional data. In this study, we present isometric SIR for nonlinear dimension reduction, which is a hybrid of the SIR method using the geodesic distance approximation. First, the proposed method computes the isometric distance between data points; the resulting distance matrix is then sliced according to K-means clustering results, and the classical SIR algorithm is applied. We show that the isometric SIR (ISOSIR) can reveal the geometric structure of a nonlinear manifold dataset (e.g., the Swiss roll). We report and discuss this novel method in comparison to several existing dimension-reduction techniques for data visualization and classification problems. The results show that ISOSIR is a promising nonlinear feature extractor for classification applications.[[incitationindex]]SCI[[booktype]]紙本[[booktype]]電子

    Utilization of COVID-19 Treatments and Clinical Outcomes among Patients with Cancer: A COVID-19 and Cancer Consortium (CCC19) Cohort Study.

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    Among 2,186 U.S. adults with invasive cancer and laboratory-confirmed SARS-CoV-2 infection, we examined the association of COVID-19 treatments with 30-day all-cause mortality and factors associated with treatment. Logistic regression with multiple adjustments (e.g., comorbidities, cancer status, baseline COVID-19 severity) was performed. Hydroxychloroquine with any other drug was associated with increased mortality versus treatment with any COVID-19 treatment other than hydroxychloroquine or untreated controls; this association was not present with hydroxychloroquine alone. Remdesivir had numerically reduced mortality versus untreated controls that did not reach statistical significance. Baseline COVID-19 severity was strongly associated with receipt of any treatment. Black patients were approximately half as likely to receive remdesivir as white patients. Although observational studies can be limited by potential unmeasured confounding, our findings add to the emerging understanding of patterns of care for patients with cancer and COVID-19 and support evaluation of emerging treatments through inclusive prospective controlled trials. SIGNIFICANCE: Evaluating the potential role of COVID-19 treatments in patients with cancer in a large observational study, there was no statistically significant 30-day all-cause mortality benefit with hydroxychloroquine or high-dose corticosteroids alone or in combination; remdesivir showed potential benefit. Treatment receipt reflects clinical decision-making and suggests disparities in medication access.This article is highlighted in the In This Issue feature, p. 1426

    brainlife.io: a decentralized and open-source cloud platform to support neuroscience research

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    Neuroscience is advancing standardization and tool development to support rigor and transparency. Consequently, data pipeline complexity has increased, hindering FAIR (findable, accessible, interoperable and reusable) access. brainlife.io was developed to democratize neuroimaging research. The platform provides data standardization, management, visualization and processing and automatically tracks the provenance history of thousands of data objects. Here, brainlife.io is described and evaluated for validity, reliability, reproducibility, replicability and scientific utility using four data modalities and 3,200 participants.The brainlife.io project development and operations were supported by awards to F.P.: grant nos. NIH NIBIB 01EB029272, R01EB030896NSF and R01EB030896; NSF BCS 1734853 and 1636893; ACI 1916518, IIS 1912270; a gift from the Kavli Foundation; Wellcome Trust grant no. 226486/Z/22/Z and a Microsoft Investigator Fellowship. Additional funding was provided to support data collection used by the team, research that used brainlife.io or infrastructure that supported the platform: grant no. NIMH UM1NS132207 BRAIN CONNECTS: Center for Mesoscale Connectomics (Principal Investigator K. Ugurbil), grant no. NIMH R01MH133701 (C.R.). NSF grant award nos. 2004877 (S.V.-B.),1541335 and 2232628 (S.M.), 1445604 and 2005506 (D.Y.H.),1341698 and 1928224 (M. Norman), 1445606 (S.T.B.), 1928147 (S.Sanalevici). NIH grant award nos. 1U54MH091657 (HCP data, Principal Investigators D. Van Essen and K. Ugurbil), U01DA041048, U01DA050989, U01DA051016, U01DA041022, U01DA051018, U01DA051037, U01DA050987, U01DA041174, 01DA041106, U01DA041117, U01DA041028, U01DA041134, U01DA050988, U01DA051039, U01DA041156, 01DA041025, U01DA041120, U01DA051038, U01DA041148, U01DA041093, U01DA041089, U24DA041123, 24DA041147 (ABCD Study, multiple Principal Investigators), P41EB017183 (J.V.), NIH NIBIB R01EB030896 (A.P.) and ANR-20-NEUC-0004-01 (mulitple Principal Investigators). Multiple philanthropic contributions to the HBN (M. Milham)

    Search for Higgs bosons produced in association with b quarks

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    We present a search for neutral Higgs bosons decaying into bb̄, produced in association with b quarks in pp̄ collisions. This process could be observable in supersymmetric models with high values of tanβ. The event sample corresponds to 2.6fb -1 of integrated luminosity collected with the CDF II detector at the Fermilab Tevatron collider. We search for an enhancement in the mass of the two leading jets in events with three jets identified as coming from b quarks using a displaced vertex algorithm. A data-driven procedure is used to estimate the dijet mass spectrum of the nonresonant multijet background. The contributions of backgrounds and a possible Higgs boson signal are determined by a two-dimensional fit of the data, using the dijet mass together with an additional variable which is sensitive to the flavor composition of the three tagged jets. We set mass-dependent limits on σ(pp̄→)×B(→bb̄) which are applicable for a narrow scalar particle produced in association with b quarks. We also set limits on tanβ in supersymmetric Higgs models including the effects of the Higgs boson width. © 2012 American Physical Society

    Observation of the Y(4140)Y(4140) structure in the J/ψϕJ/\psi\,\phi Mass Spectrum in B±J/ψϕKB^\pm\to J/\psi\,\phi K cays

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    The observation of the Y(4140)Y(4140) structure in B±J/ψϕK±B^\pm\rightarrow J/\psi\,\phi K^\pm decays produced in pˉp\bar{p} p collisions at \sqrt{s}=1.96~\TeV is reported with a statistical significance greater than 5 standard deviations. A fit to the J/ψϕJ/\psi\,\phi mass spectrum is performed assuming the presence of a Breit-Wigner resonance. The fit yields a signal of 195+619^{+6}_{-5} resonance events, and resonance mass and width of 4143.4^{+2.9}_{-3.0}(\mathrm{stat})\pm0.6(\mathrm{syst})~\MeVcc and 15.3^{+10.4}_{-6.1}(\mathrm{stat})\pm2.5(\mathrm{syst})~\MeVcc respectively. The parameters of this resonance-like structure are consistent with values reported from an earlier CDF analysis.Comment: 7 pages, 2 figures, submited to Phys. Rev. Let

    Measurement of the total cross section and ρ -parameter from elastic scattering in pp collisions at √s=13 TeV with the ATLAS detector

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    In a special run of the LHC with β⋆=2.5 km, proton–proton elastic-scattering events were recorded at s√=13 TeV with an integrated luminosity of 340 μb−1 using the ALFA subdetector of ATLAS in 2016. The elastic cross section was measured differentially in the Mandelstam t variable in the range from −t=2.5⋅10−4 GeV2 to −t=0.46 GeV2 using 6.9 million elastic-scattering candidates. This paper presents measurements of the total cross section σtot, parameters of the nuclear slope, and the ρ-parameter defined as the ratio of the real part to the imaginary part of the elastic-scattering amplitude in the limit t→0. These parameters are determined from a fit to the differential elastic cross section using the optical theorem and different parameterizations of the t-dependence. The results for σtot and ρ are σtot(pp→X)=104.7±1.1 mb ,ρ=0.098±0.011. The uncertainty in σtot is dominated by the luminosity measurement, and in ρ by imperfect knowledge of the detector alignment and by modelling of the nuclear amplitude.publishedVersio
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