40 research outputs found
Suppression of charged particle production at large transverse momentum in central Pb-Pb collisions at sNN=2.76 TeV
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- T.S. R\ue4ih\ue4af
- T.S. Tveterbg
- U. Frankenfelds
- U. Fuchsf
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- U. Westerhoffap
- V. Altini r
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- Y. Wangbm
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- Z.L. Matthews an
- Publication venue
- 'Elsevier BV'
- Publication date
- 07/12/2010
- Field of study
Inclusive transverse momentum spectra of primary charged particles in Pb-Pb
collisions at sNN = 2.76 TeV have been measured by the ALICE
Collaboration at the LHC. The data are presented for central and peripheral
collisions, corresponding to 0-5% and 70-80% of the hadronic Pb-Pb cross
section. The measured charged particle spectra in ∣η∣<0.8 and 0.3<pT<20 GeV/c are compared to the expectation in pp collisions at the same
sNN, scaled by the number of underlying nucleon-nucleon
collisions. The comparison is expressed in terms of the nuclear modification
factor RAA. The result indicates only weak medium effects (RAA≈ 0.7) in peripheral collisions. In central collisions, RAA
reaches a minimum of about 0.14 at pT=6-7GeV/c and increases
significantly at larger pT. The measured suppression of high-pT particles is stronger than that observed at lower collision energies,
indicating that a very dense medium is formed in central Pb-Pb collisions at
the LHC.Comment: 15 pages, 5 captioned figures, 3 tables, authors from page 10,
published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/98
Two-pion Bose-Einstein correlations in central Pb-Pb collisions at sNN = 2.76 TeV
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- A. Abrahantes Quintana b
- A. Ahmad Masoodi j
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- A. Alici o
- A. Alkinp
- A. Andronic s
- A. Arendab
- A. Asryant
- A. Augustinus f
- A. Badal\ue0 ag
- A. Baldisseri aj
- A. Balditak
- A. Bercuci u
- A. Bhasinav
- A. Bilandzic az
- A. Blancak
- A. Bogdanovbc
- A. Casanova D\uedaz aw
- A. Daineseca
- A. Danucb
- A. Dashcc
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- A. De Caroce
- A. De Falcocg
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- A. Deppman cd
- A. Di Maurof
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- A. Fedunovaq
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- A. Rachevski cl
- A. Rademakers f
- A. Rakotozafindrabe aj
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- A. Reshetinck
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- A. Vinogradovm
- A. Vodopyanov aq
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- A. Zeninbd
- A. Zichichi o
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- A.J. Peters f
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- A.M. Adared
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- B. Alessandro n
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- B. Chang af
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- B. Sitarbj
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- be
- Bregant M.
- C. Andrei u
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- C. Cavicchioli f
- C. Cheshkovbq
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- C. Di Giglio r
- C. Furgetac
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- C. Guerra Gutierrez bo
- C. Hadjidakisbg
- C. Hern\ue1ndez s
- C. Ivans
- C. Klein-B\uf6sing ap
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- C. Kuhnas
- C. Larav
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- C. Lippmann f
- C. Loizidesct
- C. Luzzi f
- C. Mitu cb
- C. Nattrass db
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- C. Soos f
- C. Suire bg
- C. Tagridis cm
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- C.H. Christensen ar
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- Camerini P.
- Contin G.
- D. Adamov\ue1c
- D. Aleksandrovm
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- D. Silvermyr ae
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- D. Swobodaf
- D. Thomasbs
- D. Tlusty ay
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- D. Vranics
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- D.A. Moreira De Godoy cd
- D.B. Piyarathna at
- D.D. Chinellato br
- D.J. Kimaf
- D.M. Madagodahettige-Don bb
- D.P. Mahapatra cc
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- D.T. Larsena
- D.W. Kimk
- E. Almar\ue1z Avi\uf1a h
- E. Belmont-Moreno h
- E. Berdermanns
- E. Biolcati f
- E. Bruna d
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- E. Chiavassa n
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- E. Cuautle bz
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- E. Gladysz-Dziadus ao
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- E. Korna\ub4s ao
- E. Kryshenau
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- G. Koyithatta Meethaleveedu cu
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- G. Ortonaf
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- G. Wilk ch
- G. Zinovjev p
- G.E. Bruno r
- G.G. Barnaf\uf6ldi g
- G.L. Usai cg
- G.M. Innocenti ah
- G.M. Urciuoli ci
- G.O.V. de Barros cd
- G.S. Pappalardo ag
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- H. Appelsh\ue4user ab
- H. B\uf8ggild ar
- H. Beckab
- H. Borel aj
- H. Buesching ab
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- H. Delagrangeaa
- H. Engel v
- H. Gonz\ue1lez Santos bx
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- I. Altsybeevt
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- I. Berceanuu
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- I. Ilkivch
- I. Kisel v
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- I. Martashvili db
- I. Otterlundbt
- I. Pshenichnov ck
- I. Rusanovf
- I. Stan cb
- I. Szarkabj
- I. Yushmanovm
- I. Zguracb
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- I.C. Arsene s
- I.G. Bearden ar
- J. \uc4yst\uf6af
- J. B\ue1nal
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- J.L. Gramling bl
- J.L. Klaycy
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- K. Kochbl
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- K. Mabn
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- K.F. Readdb
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- M. L\uf3pez Noriega bg
- M. Lenhardt aa
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- M. Malaev au
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- M. Rammler ap
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- M. Siciliano ah
- M. Sittaby
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- Margagliotti G.
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- R. Alfaro Molina h
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- R. Ilkaevbk
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- R. Soltzde
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- R. Vernet di
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- R.A. Ricci ca
- R.P. Scharenbergdh
- Rui R.
- S. Aguilar Salazar h
- S. Altinpinar s
- S. Arcelli o
- S. B\uf6ttger v
- S. Bagnasco n
- S. Beoleah
- S. Bose bf
- S. Chapeland f
- S. Chattopadhyay i
- S. Chattopadhyaybf
- S. Coli n
- S. Dashn
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- S. Dei
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- S. Esumi bu
- S. Evrard f
- S. Filchagin bk
- S. Foertsch bm
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- S. Huber s
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- S. Jenacu
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- S. Kim cs
- S. Kirsch f
- S. Kiselevl
- S. Koxac
- S. Kushpil c
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- S. Lohn f
- S. Masciocchi s
- S. Morettoax
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- S. Nikolaev m
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- S.U. Ahnk
- T. Altq
- T. Anti\u2c7ci \ub4c x
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- T. Dietel ap
- T. Dobrowolski ch
- T. Gunji cr
- T. Horaguchi bu
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- T. Sinha bf
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- T. Susa x
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- T.B. Skaali bh
- T.C. Awesae
- T.J. Humanicw
- T.J.M. Symons ct
- T.K. Nayaki
- T.M. Cormier at
- T.S. R\ue4ih\ue4af
- T.S. Tveterbh
- U. Frankenfelds
- U. Fuchsf
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- U. Westerhoffap
- V. Altini r
- V. Anguelov v
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- V. Catanescu u
- V. Chibante Barroso f
- V. Demanovbk
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- V. Grabski h
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- V. Kaplinbc
- V. Kondratiev t
- V. Kushpil c
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- V. Lenti cf
- V. Lindenstruth v
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- V. Mankom
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- V. Muccifora aw
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- V. Nikulin au
- V. Paticchio cf
- V. Peskovf
- V. Petr\ue1\u2c7cek ay
- V. Posp\ued\u161il ay
- V. Puninbk
- V. Samsonov au
- V. Vechernin t
- V. Wagneray
- V.R. Loggins at
- Venaruzzo M.
- W. Carena f
- W. Jung k
- W. Perytcn
- W. Rieglerf
- W.H. Trzaskaaf
- W.J. Parks
- X. Cai bn
- X. Li cz
- X. Lopezak
- X. Yuanbn
- X. Zhang bn
- X. Zhubn
- X.-G. Lu bl
- Y. Berdnikov au
- Y. Corrales Morales ah
- Y. Delgado Mercado bo
- Y. Hori cr
- Y. Kharlovbd
- Y. Kucheriaevm
- Y. Kwoncw
- Y. Le Bornec bg
- Y. Maobn
- Y. Martynov p
- Y. Miake bu
- Y. Pachmayerbl
- Y. Pestovdf
- Y. Schutzaa
- Y. Sibiriakm
- Y. Vinogradov bk
- Y. Wangbl
- Y. Wangbn
- Y. Zoccarato bq
- Y.P. Viyogi i
- Y.W. Baekk
- Z. Ahammed i
- Z. Buthelezi bm
- Z. Conesa del Valle aa
- Z. Vilakazi bm
- Z. Yinbn
- Z.L. Matthews an
- Publication venue
- 'Elsevier BV'
- Publication date
- 21/12/2010
- Field of study
The first measurement of two-pion Bose-Einstein correlations in central Pb-Pb
collisions at sNN=2.76 TeV at the Large Hadron Collider is
presented. We observe a growing trend with energy now not only for the
longitudinal and the outward but also for the sideward pion source radius. The
pion homogeneity volume and the decoupling time are significantly larger than
those measured at RHIC.Comment: 17 pages, 5 captioned figures, 1 table, authors from page 12,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/388
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
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- Aamer A
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- Abantanga F
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- Abbasy J
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- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
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- Abdel-Kader SM
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- Abdelaty M
- Abdelazeam AR
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- Abdelaziz MA
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- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelhady S
- Abdelhamed R
- Abdelhamid A
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- Abdulhakeem EM
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- Abdullah MA
- Abdullah N
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- Abdurrazzaaq A
- Abebe NS
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- Abem OE
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- Appeadu-Mensah W
- Appiah EK
- Aql S
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- Aranzabal Durand SY
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- Arevalo Azmitia JR
- Arias Pacheco RD
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- Aziz MRA
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- Azizeldine MG
- Azmitia Mendizabal CA
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- Badr A
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- Balducci G
- Balila RMH
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- Balogun F
- Baltrunas R
- Baluch F
- Bamford R
- Bamicha A
- Bamicha A
- Banaitis VJ
- Bandi A
- Bandoh D
- Bani-Sadar A
- Banipal GS
- Baraka H
- Barakat SAE
- Barendegere V
- Barker T
- Barkolias C
- Barmayehvar B
- Barnabas GN
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- Barneo L
- Barrionuevo Ojeda RR
- Barrios E
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- Barros De Castro Segundo LC
- Barroso de Lima CV
- Barry J
- Basilico S
- Basir ERM
- Bassem M
- Bassit KA
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- Batt J
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- Beamon M
- Beasley W
- Beaton C
- Bedada AG
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- Behar N
- Beisa V
- Beisa V
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- Bennai RM
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- Bhargava A
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- Bhopal KF
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- Bianco F
- Bigaran A
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- Bin Ismail MJ
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- Mirza A
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- Mohamed M
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- Montrimaite M
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- Samaraweera DI
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- Tansoker I
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- Tarek D
- Targa S
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- Tedeschi U
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- Telfah MM
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- Ukwenya Y
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- Upchurch E
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- Urbina Rojas NM
- Urbonas T
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- Urniezius Z
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- Uscinas L
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- Vianna JGP
- Vicario E
- Vicenta Collado M
- Vida LC
- Vida LC
- Vilcinskas M
- Villa R
- Villalobos S
- Vimalachandran D
- Vincent J
- Violi P
- Visinskas P
- Vivekanantham S
- Vlachogiorgos A
- Voulgaris E
- Wael N
- Wagener M
- Wakefield R
- Waledziak M
- Waleed H
- Walker M
- Walker N
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- Walsh U
- Waqar M
- Ward AE
- Ward S
- Warda M
- Warren O
- Warren O
- Warwick AM
- Waterman A
- Watson NF
- Watson NF
- Watts A
- Weber B
- Weber P
- Weber P
- Weinstein MS
- Weiser TG
- Werder G
- Wheeler J
- Whewell H
- Whitaker J
- White R
- White T
- Whitehurst K
- Wiborg J
- Widiastini TA
- Widmer LW
- Wijayarathna LS
- Wild JRL
- Williams E
- Williams G
- Williams O
- Williams O
- Williamson A
- Wilson A
- Wilson L
- Wilson M
- Wilson M
- Wilson MSJ
- Wilson MSJ
- Wimalge PMSN
- Winstanley J
- Witherspoon P
- Wogensen F
- Wogensen F
- Wogensen F
- Woin E
- Wold TB
- Wolf B
- Wolf B
- Wondimu S
- Wondoh P
- Wondoh P
- Wong CS
- Wong CY
- Wong F
- Wong HY
- Wood G
- Woodward H
- Worku M
- Worku M
- Worku T
- Wredberg C
- Wright N
- Wright NJ
- Xerri T
- Xerri T
- Yahaya MT
- Yakubu M
- Yallop L
- Yam SY
- Yang J
- Yap S
- Yaseen T
- Yaseen TM
- Yau JD
- Yavuz MA
- Ye J
- Yeang LJ
- Yee J
- Yeo LS
- Yeung ENW
- Yeung MHA
- Yifieyeh A
- Yildirim R
- Yip C
- Ymeri S
- Yoganathan P
- Yolcu S
- Yong CO
- Yong GL
- Younis A
- Youssef D
- Youssef H
- Youssef M
- Youssif JH
- Yuksek MA
- Yusufali T
- Zaa'treh R
- Zachariades D-C
- Zadoroznas A
- Zahran D
- Zakaria E
- Zakaria M
- Zakaria Y
- Zaki A
- Zakir M
- Zalabia MF
- Zamarin K
- Zammit S
- Zampitis N
- Zani A
- Zani A
- Zani A
- Zanini N
- Zanini N
- Zapata Ponze De Leon M
- Zapata Ponze De Leon M
- Zapata F
- Zarb C
- Zardab A
- Zegarra S
- Zeidan S
- Zelada Alvarez II
- Zerihun AB
- Zeta Solis LA
- Zhang Z
- Zheng F
- Zidan H
- Zidan H
- Zidan M
- Zielinski M
- Ziff O
- Zikry M
- Zil-E-Ali A
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskas J
- Zilinskiene R
- Zilinskiene R
- Zimmermann EF
- Ziubryte G
- Zohair A
- Zorrilla CD
- Zuber M
- Zuber M
- Zuk G
- Zulkifli A
- Zumbuhl L
- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019 : a comprehensive demographic analysis for the Global Burden of Disease Study 2019
- Author
- Abbas KM
- Abbasi-Kangevari M
- Abbasifard M
- Abbastabar H
- Abd El Razek HM
- Abd El Razek MM
- Abd-Allah F
- Abdelalim A
- Abdulkader RS
- Abdullah KH
- Abolhassani H
- Abreu LG
- Abrigo MRM
- Abushouk AI
- Adabi M
- Adair T
- Adebayo OM
- Adedeji IA
- Adekanmbi V
- Adeoye AM
- Adetokunboh OO
- Advani SM
- Afshin A
- Aghaali M
- Agrawal A
- Ahmadi K
- Ahmadieh H
- Ahmed MB
- Al-Aly Z
- Al-Mekhlafi HM
- Alam K
- Alam T
- Alanezi FM
- Alanzi TM
- Alcalde-Rabanal JE
- Ali M
- Alicandro G
- Alijanzadeh M
- Alinia C
- Alipour V
- Alizade H
- Aljunid SM
- Allebeck P
- Almadi MAH
- Almasi-Hashiani A
- Altirkawi KA
- Alumran AK
- Alvis-Guzman N
- Amini-Rarani M
- Aminorroaya A
- Amit AML
- Ancuceanu R
- Andrei CL
- Androudi S
- Angus C
- Anjomshoa M
- Ansari F
- Ansari I
- Ansari-Moghaddam A
- Antonio CAT
- Antony CM
- Anvari D
- Appiah SCY
- Arab-Zozani M
- Arabloo J
- Aravkin AY
- Aremu O
- Arnlov J
- Aryal KK
- Asadi-Pooya AA
- Asgari S
- Atteraya MS
- Ausloos M
- Avila-Burgos L
- Avokpaho EFGA
- Ayano G
- Ayanore MA
- Azarian G
- Babaee E
- Badiye AD
- Bagli E
- Bahrami MA
- Bakhtiari A
- Balassyano S
- Bali AO
- Banach M
- Bandpei MAM
- Banik PC
- Barker-Collo SL
- Barnighausen TW
- Barzegar A
- Basu S
- Baune BT
- Bayati M
- Bazmandegan G
- Bedi N
- Bell ML
- Bennett DA
- Bensenor IM
- Berhe K
- Berman AE
- Bertolacci GJ
- Bhageerathy R
- Bhala N
- Bhattacharyya K
- Bhutta ZA
- Bijani A
- Bin Zaman S
- Biondi A
- Bisanzio D
- Bisignano C
- Biswas RK
- Bjrge T
- Bohlouli S
- Bohluli M
- Bolla SRR
- Borzi AM
- Borzouei S
- Brady OJ
- Braithwaite D
- Brauer M
- Briko AN
- Briko NI
- Bumgarner BR
- Butt ZA
- Cai T
- Callender CSKH
- Camera LLAA
- Campos-Nonato IR
- Car LT
- Cardenas R
- Carreras G
- Carrero JJ
- Carvalho F
- Castaldelli-Maia JM
- Castelpietra G
- Castro F
- Catala-Lopez F
- Cederroth CR
- Cerin E
- Chattu VK
- Chin KL
- Chu D-T
- Ciobanu LG
- Cirillo M
- Comfort H
- Costa VM
- Cowden RG
- Cromwell EA
- Croneberger AJ
- Cunningham M
- D'Amico E
- da Silva DD
- Dahlawi SMA
- Damiani G
- Dandona L
- Dandona R
- Dargan PI
- Darwesh AM
- Daryani A
- Das Gupta R
- das Neves J
- Davletov K
- De Leo D
- Defo BK
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- Do HT
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- Dorostkar F
- dos Santos FLC
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- Effiong A
- El Sayed I
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- Jacobsen KH
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- Kassebaum NJ
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- Krishan K
- Krohn KJ
- Kumar GA
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- Leonardi M
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- Logroscino G
- Lopez AD
- Lopukhov PD
- Lotufo PA
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- Maddison ER
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- Mapoma CC
- Martini S
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- Masaka A
- Mastrogiacomo CI
- Mathur MR
- May EA
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- McKee M
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- Meitei WB
- Memiah PTN
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- Mengesha EW
- Mensah GA
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- Milne GJ
- Mirrakhimov EM
- Mirzaei H
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- Nansseu JR
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- Patel JR
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- Piradov MA
- Pirsaheb M
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- Postma MJ
- Pourjafar H
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- Prakash S
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- Quintanilla BPA
- Rabiee M
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- Rafiei A
- Raggi A
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- Rashedi V
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- Renjith V
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- Rubagotti E
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- Santric-Milicevic MM
- Saraswathy SYI
- Sartorius B
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- Schwebel DC
- Schwendicke F
- Sekerija M
- Senbeta AM
- Senthilkumaran S
- Sepanlou SG
- Servan-Mori E
- Shabani M
- Shahabi S
- Shahbaz M
- Shaheen AA
- Shaikh MA
- Shalash AS
- Shams-Beyranvand M
- Shamsi M
- Shamsizadeh M
- Shannawaz M
- Sharafi K
- Sharafi Z
- Sharara F
- Sharma R
- Shaw DH
- Sheikh A
- Shiri R
- Shrime MG
- Shuval K
- Siabani S
- Sigfusdottir ID
- Sigurvinsdottir R
- Silva DAS
- Simonetti B
- Simpson KE
- Singh JA
- Skiadaresi E
- Skryabin VY
- Soheili A
- Sokhan A
- Sorensen RJD
- Soriano JB
- Sorrie MB
- Soyiri IN
- Spurlock EE
- Sreeramareddy CT
- Stockfelt L
- Stokes MA
- Stubbs JL
- Sudaryanto A
- Sufiyan MB
- Syed ZQ
- Sykes BL
- Tabares-Seisdedos R
- Tabb KM
- Tadakamadla SK
- Taherkhani A
- Tang M
- Taveira N
- Taylor HJ
- Teagle WL
- Tehrani-Banihashemi A
- Teklehaimanot BF
- Tessema ZT
- Thankappan KR
- Thomas N
- Thrift AG
- Titova MV
- Tohidinik HR
- Tonelli M
- Topor-Madry R
- Topouzis F
- Toroudi HP
- Tovani-Palone MRR
- Traini E
- Tran BX
- Travillian R
- Trias-Llimos S
- Truelsen TC
- Unnikrishnan B
- Upadhyay E
- Vacante M
- Vakilian A
- Valdez PR
- Valli A
- Vardavas C
- Vasankari TJ
- Vasconcelos AMN
- Vasseghian Y
- Veisani Y
- Velasquez IM
- Venketasubramanian N
- Vidale S
- Violante FS
- Vlassov V
- Vollset SE
- Vos T
- Vujcic IS
- Vukovic A
- Vukovic R
- Waheed Y
- Wallin MT
- Walters MK
- Wang H
- Wang H
- Wang Y-P
- Watson S
- Wei J
- Weiss J
- Weldesamuel GT
- Werdecker A
- Westerman R
- Whiteford HA
- Wiangkham T
- Wiens KE
- Wijeratne T
- Wiysonge CS
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- Wolfe CDA
- Wondmieneh AB
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- Yamagishi K
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- Yip P
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- York HW
- Younis MZ
- Younker TP
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- Yousefinezhadi T
- Yousuf AY
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- Zandian H
- Zhang Z-J
- Zheng P
- Zhou M
- Ziapour A
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Background Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019. Methods 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate age-specific fertility rates for 5-year age groups between ages 15 and 49 years. With extensions to age groups 10-14 and 50-54 years, the total fertility rate (TFR) was then aggregated using the estimated age-specific fertility between ages 10 and 54 years. 7417 sources were used for under-5 mortality estimation and 7355 for adult mortality. ST-GPR was used to synthesise data sources after correction for known biases. Adult mortality was measured as the probability of death between ages 15 and 60 years based on vital registration, sample registration, and sibling histories, and was also estimated using ST-GPR. HIV-free life tables were then estimated using estimates of under-5 and adult mortality rates using a relational model life table system created for GBD, which closely tracks observed age-specific mortality rates from complete vital registration when available. Independent estimates of HIV-specific mortality generated by an epidemiological analysis of HIV prevalence surveys and antenatal clinic serosurveillance and other sources were incorporated into the estimates in countries with large epidemics. Annual and single-year age estimates of net migration and population for each country and territory were generated using a Bayesian hierarchical cohort component model that analysed estimated age-specific fertility and mortality rates along with 1250 censuses and 747 population registry years. We classified location-years into seven categories on the basis of the natural rate of increase in population (calculated by subtracting the crude death rate from the crude birth rate) and the net migration rate. We computed healthy life expectancy (HALE) using years lived with disability (YLDs) per capita, life tables, and standard demographic methods. Uncertainty was propagated throughout the demographic estimation process, including fertility, mortality, and population, with 1000 draw-level estimates produced for each metric. Findings The global TFR decreased from 2.72 (95% uncertainty interval [UI] 2.66-2.79) in 2000 to 2.31 (2.17-2.46) in 2019. Global annual livebirths increased from 134.5 million (131.5-137.8) in 2000 to a peak of 139.6 million (133.0-146.9) in 2016. Global livebirths then declined to 135.3 million (127.2-144.1) in 2019. Of the 204 countries and territories included in this study, in 2019, 102 had a TFR lower than 2.1, which is considered a good approximation of replacement-level fertility. All countries in sub-Saharan Africa had TFRs above replacement level in 2019 and accounted for 27.1% (95% UI 26.4-27.8) of global livebirths. Global life expectancy at birth increased from 67.2 years (95% UI 66.8-67.6) in 2000 to 73.5 years (72.8-74.3) in 2019. The total number of deaths increased from 50.7 million (49.5-51.9) in 2000 to 56.5 million (53.7-59.2) in 2019. Under-5 deaths declined from 9.6 million (9.1-10.3) in 2000 to 5.0 million (4.3-6.0) in 2019. Global population increased by 25.7%, from 6.2 billion (6.0-6.3) in 2000 to 7.7 billion (7.5-8.0) in 2019. In 2019, 34 countries had negative natural rates of increase; in 17 of these, the population declined because immigration was not sufficient to counteract the negative rate of decline. Globally, HALE increased from 58.6 years (56.1-60.8) in 2000 to 63.5 years (60.8-66.1) in 2019. HALE increased in 202 of 204 countries and territories between 2000 and 2019. Interpretation Over the past 20 years, fertility rates have been dropping steadily and life expectancy has been increasing, with few exceptions. Much of this change follows historical patterns linking social and economic determinants, such as those captured by the GBD Socio-demographic Index, with demographic outcomes. More recently, several countries have experienced a combination of low fertility and stagnating improvement in mortality rates, pushing more populations into the late stages of the demographic transition. Tracking demographic change and the emergence of new patterns will be essential for global health monitoring. Copyright (C) 2020 The Author(s). Published by Elsevier Ltd.Peer reviewe
Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Abbafati C
- Abbas KM
- Abbasi M
- Abbasi-Kangevari M
- Abbasifard M
- Abbastabar H
- Abd El Razek HM
- Abd El Razek MM
- Abd-Allah F
- Abdelalim A
- Abdollahi M
- Abdollahpour I
- Abdulkader RS
- Abdullah KH
- Abedi A
- Abedi P
- Abegaz KH
- Abolhassani H
- Abosetugn AE
- Aboyans V
- Abrams EM
- Abreu LG
- Abrigo MRM
- Abu Haimed AK
- Abu-Gharbieh E
- Abu-Raddad LJ
- Abualhasan A
- Abushouk AI
- Acebedo A
- Ackerman IN
- Adabi M
- Adair T
- Adamu AA
- Adebayo OM
- Adedeji IA
- Adekanmbi V
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- Troeger CE
- Truelsen TC
- Tsai AC
- Tsatsakis A
- Tyrovolas S
- Uddin R
- Ullah I
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- Umeokonkwo CD
- Undurraga EA
- Unnikrishnan B
- Upadhyay E
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- Valdez PR
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- Venketasubramanian N
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- Wondmieneh AB
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- Wu A-M
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- Wunrow HY
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- Yaminfirooz M
- Yano Y
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- Yilgwan CS
- Yilma MT
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- Younker TP
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- Yousefi Z
- Yousefifard M
- Yousefinezhadi T
- Yousuf AY
- Yu C
- Yu Y
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- Yuce D
- Yusefzadeh H
- Zadey S
- Zahabi SS
- Zaidi SS
- Zaki L
- Zaki MES
- Zakzuk J
- Zamani M
- Zamanian M
- Zandian H
- Zangeneh A
- Zarafshan H
- Zastrozhin MS
- Zewdie KA
- Zhang J
- Zhang Y
- Zhang Z-J
- Zhao JT
- Zhao X-JG
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- Zheleva B
- Zheng P
- Zhou M
- Zhu C
- Ziapour A
- Zimsen SRM
- Zlavog BS
- Zodpey S
- Publication venue
- 'Elsevier BV'
- Publication date
- 17/10/2020
- Field of study
Five insights from the Global Burden of Disease Study 2019
- Author
- Abbafati C
- Abbas KM
- Abbasi M
- Abbasi-Kangevari M
- Abbasifard M
- Abbastabar H
- Abd El Razek HM
- Abd El Razek MM
- Abd-Allah F
- Abdelalim A
- Abdollahi M
- Abdollahpour I
- Abdulkader RS
- Abdullah KH
- Abedi A
- Abedi P
- Abegaz KH
- Abolhassani H
- Abosetugn AE
- Aboyans V
- Abrams EM
- Abreu LG
- Abrigo MRM
- Abu Haimed AK
- Abu-Gharbieh E
- Abu-Raddad LJ
- Abualhasan A
- Abushouk AI
- Acebedo A
- Ackerman IN
- Adabi M
- Adair T
- Adamu AA
- Adebayo OM
- Adedeji IA
- Adekanmbi V
- Adelson JD
- Adeoye AM
- Adetokunboh OO
- Adham D
- Advani SM
- Afarideh M
- Afshari M
- Afshin A
- Agardh EE
- Agarwal G
- Agasthi P
- Agesa KM
- Aghaali M
- Aghamir SMK
- Agrawal A
- Ahmad T
- Ahmadi A
- Ahmadi K
- Ahmadi M
- Ahmadieh H
- Ahmadpour E
- Ahmed MB
- Aji B
- Akalu TY
- Akinyemi RO
- Akinyemiju T
- Akombi B
- Akunna CJ
- Al-Aly Z
- Al-Mekhlafi HM
- Al-Raddadi RM
- Alahdab F
- Alam K
- Alam N
- Alam S
- Alam T
- Alanezi FM
- Alanzi TM
- Albertson SB
- Alcalde-Rabanal JE
- Alema NM
- Alemu BW
- Alemu YM
- Alhabib KF
- Alhassan RK
- Ali M
- Ali S
- Alicandro G
- Alijanzadeh M
- Alinia C
- Alipour V
- Alizade H
- Aljunid SM
- Alla F
- Allebeck P
- Almadi MAH
- Almasi A
- Almasi-Hashiani A
- Almasri NA
- Almulhim AM
- Alonso J
- Altirkawi KA
- Alumran AK
- Alvis-Guzman N
- Alvis-Zakzuk NJ
- Amare AT
- Amare B
- Amini S
- Amini-Rarani M
- Aminorroaya A
- Amiri F
- Amit AML
- Amugsi DA
- Amul GGH
- Anbesu EW
- Ancuceanu R
- Anderlini D
- Anderson JA
- Andrei CL
- Andrei T
- Androudi S
- Angus C
- Anjomshoa M
- Ansari F
- Ansari I
- Ansari-Moghaddam A
- Antonazzo IC
- Antonio CAT
- Antony CM
- Antriyandarti E
- Anvari D
- Anwer R
- Appiah SCY
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- Arabloo J
- Aravkin AY
- Arba AAK
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- Arowosegbe OO
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- Asadi-Pooya AA
- Asgari S
- Asghari B
- Ashbaugh C
- Assmus M
- Atafar Z
- Athari SS
- Atnafu DD
- Atout MMW
- Atre SR
- Atteraya MS
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- Avokpaho EFGA
- Ayano G
- Ayanore MA
- Aynalem GL
- Aynalem YA
- Ayza MA
- Azari S
- Azarian G
- Azene ZN
- Azhar G
- Azzopardi PS
- Babaee E
- Badawi A
- Badiye AD
- Bagherzadeh M
- Bagli E
- Bahrami MA
- Baig AA
- Bairwa M
- Bakhshaei MH
- Bakhtiari A
- Bakkannavar SM
- Balachandran A
- Balakrishnan S
- Balalla S
- Balassyano S
- Baldasseroni A
- Bali AO
- Ball K
- Ballew SH
- Balzi D
- Banach M
- Bandpei MAM
- Banerjee SK
- Banik PC
- Bannick MS
- Bante AB
- Bante SA
- Baraki AG
- Barboza MA
- Barker-Collo SL
- Barnighausen TW
- Barrero LH
- Barthelemy CM
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- Bibi S
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- Bilano V
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- Birihane BM
- Bisanzio D
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- Breitner S
- Brenner H
- Breusov AV
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- Briko AN
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- Britton GB
- Brugha T
- Bryazka D
- Buchbinder R
- Bumgarner BR
- Burkart K
- Burnett RT
- Busse R
- Butt ZA
- Caetano dos Santos FL
- Cahill LE
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- Camera LA
- Campos-Nonato IR
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- Carrero JJ
- Carvalho F
- Castaldelli-Maia JM
- Castaneda-Orjuela CA
- Castelpietra G
- Castle CD
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- Causey K
- Cederroth CR
- Cercy KM
- Cerin E
- Chalek J
- Chandan JS
- Chang AR
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- Dahlawi SMA
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- Dai H
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- Dean FE
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- Demoz GT
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- Desalew A
- Dessie GA
- Deuba K
- Dharmaratne SD
- Dhungana GP
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- Dichgans M
- Didarloo A
- Dingels ZV
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- Dirac MA
- Djalalinia S
- Do HT
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- Doku DT
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- Dolgert AJ
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- Doshi CP
- Doshi PP
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- Douiri A
- Doxey MC
- Doyle KE
- Driscoll TR
- Dubljanin E
- Dunachie SJ
- Duncan BB
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- Ebrahimi H
- Edvardsson D
- Effiong A
- Ehrlich JR
- El Nahas N
- El Sayed I
- El Tantawi M
- El-Jaafary SI
- Elbarazi I
- Elgendy IY
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- Elyazar IRF
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- Farahmand M
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- Faro A
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- Fazaeli AA
- Fazlzadeh M
- Feigin VL
- Feldman R
- Fereshtehnejad S-M
- Fernandes E
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- Ferreira ML
- Feyissa GT
- Filip I
- Fischer F
- Fisher JL
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- Flohr C
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- Folayan MO
- Fomenkov AA
- Force LM
- Fornari C
- Forooshani ZSD
- Foroutan M
- Fox JT
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- Frank TD
- Franklin RC
- Freitas M
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- Fukumoto T
- Fukutaki K
- Fuller JE
- Fullman N
- Furtado JM
- Gad MM
- Gaidhane AM
- Gakidou E
- Galles NC
- Gallus S
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- Garcia-Basteiro AL
- Gardner WM
- Geberemariyam BS
- Gebrehiwot AM
- Gebremedhin KB
- Gebremeskel GG
- Gebremeskel LG
- Gebresillassie BM
- Gebreslassie AAAA
- Gela JD
- Geramo YCD
- Geremew A
- Gesesew HA
- Gething PW
- Gezae KE
- Ghadimi M
- Ghadiri K
- Ghaffarifar F
- Ghafourifard M
- Ghajar A
- Ghamari F
- Ghashghaee A
- Ghiasvand H
- Ghith N
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- Gilani SA
- Gill PS
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- Guled RA
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- Field of study
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD 2019 incorporates data from 281 586 sources and provides more than 3.5 billion estimates of health outcome and health system measures of interest for global, national, and subnational policy dialogue. All GBD estimates are publicly available and adhere to the Guidelines on Accurate and Transparent Health Estimate Reporting. From this vast amount of information, five key insights that are important for health, social, and economic development strategies have been distilled. These insights are subject to the many limitations outlined in each of the component GBD capstone papers.Peer reviewe
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
- Author
- Abbott TE
- Abdallah RI
- Abdel-Aal IR
- Abdelmonem SA
- Abdo WF
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- Abellán AN
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- AKI Research Group
- Akiduki N
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- Castellana D
- Castellanos A
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- Castillo-Lorente E
- Castillo-Lorente E
- Catalan M
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- Chemam S
- Chen CM
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- Chen GQ
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- Cheng CC
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- Chernyshuk S
- Chevret S
- Chhor V
- Chiang CC
- Chiang CH
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- Chiappa C
- Chiou KR
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- Chiu LC
- Chiumello D
- Chiurazzi C
- Chiurazzi C
- Cho Y
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- Cholley B
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- Chou W
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- Chouvarda I
- Christopher KB
- Chrétien JM
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- Chumaev A
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- Chytas A
- Cinel I
- Cinnella G
- Citerio G
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- Clemente EA
- Clermont G
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- Colaprico A
- Colino L
- Collange O
- Colombo A
- Colombo A
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- Concha P
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- Constan A
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- Conti G
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- Cordero M
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- Cordovilla-Guardia S
- Cordón J
- Corona A
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- Curtis A
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- Cutuli SL
- Câmara M
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- da Silva VZ
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- Dalhuisen A
- Dalorzo M
- Damas P
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- De Brito-Ashurst I
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- De Freitas FF
- De Gasperi A
- de Hoyos EA
- De la Calle-Pedrosa N
- de la Fuente MV
- De La Fuente-Martos C
- De La Fuente-Martos C
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- De Pascale G
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- De Sanctis F
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- De Sousa I
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- Deblier I
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- Elgendy M
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- Engelberts D
- ENVIN-HELICS Study Group
- Erb J
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- Fernández L
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- Fernández-Mondéjar E
- Fernández-Ortega JF
- Ferraz AB
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- FINNRESUSCI Study Group
- Fischer G
- Fleischmann E
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- Flowers E
- Follin A
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- Fontaiña LP
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- Frithiof R
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- FROG ICU Investigators
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- GETGAG Working Group
- GETGAG/SEMICYUC
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- IPREA Study Group
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- Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group
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- JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group
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- Juanas CA
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- Kumbamu A
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- Midwinter MJ
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- Miguelena PR
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- Mora-Ordóñez JM
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- Morán I
- Motos A
- Mouaci A
- Mourad M
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- Nieto OR
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- Nisula S
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- Noda E
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- Oddo M
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- Ohta Y
- Oikonomou M
- Oikonomou M
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- Okahara S
- Okamoto H
- Okayama Research Investigation Organizing Network (ORION)investigators
- Olaechea P
- Olavarria E
- Olea-Jiménez V
- Olivares F
- Olkkola KT
- Ong C
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- Ono Y
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- Onodera M
- Oobayashi W
- Orden VA
- Ori C
- Orlando A
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- Ostermann M
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- Pakhare A
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- Paldusová B
- Palencia E
- Palencia E
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- Palomar M
- Panafidina V
- Panciera G
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- Papazian L
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- PICS- HCPA: Programa Intrahospitalar de Combate à Sepse do Hospital de Clínicas de Porto Alegre
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- Pinto JL
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- Pozzi M
- Pozzi M
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- Pratikaki M
- Pravettoni D
- Prazeres PH
- Preau S
- Preece J
- Preiser JC
- Price RD
- Prieto J
- Privato E
- Prosperi M
- Prowle JR
- Prīdāne S
- PS-ICU Group
- Psarologakis C
- Puerto-Morlán A
- Pugliese F
- Pujol LM
- Pulham RA
- Pulitano' SM
- Pusapati R
- Puthucheary ZA
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- Putzu A
- Puybasset L
- Pérez A
- Pérez AG
- Pérez H
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- Pérez LP
- Pérez LP
- Qiu H
- Quinart A
- Quintana S
- Quintana S
- Quintel M
- Quinza A
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- Radjou A
- Radu V
- Rai S
- Ramazanoglu A
- Ramelli A
- Ramelli A
- Ramirez JR
- Ramirez P
- Ramirez P
- Ramirez V
- Ramnarayan P
- Ramnarayan P
- Ramos A
- Ramos JV
- Ramos JV
- Ramos JV
- Ramírez CS
- Ramírez CS
- Ramírez JR
- Ranse K
- Ranzani OT
- Rapid Diagnosis of Infections in the Critically Ill Team
- Rattray J
- Raurich JM
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- Reiter A
- Rello J
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- Renes-Carreño E
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- Repessé X
- Resche-Rigon M
- Restrepo MI
- Reusch S
- ReVA Research Network and the PROVE Network Investigators
- Revel N
- Revuelto-Rey J
- Rey JR
- Reyes LF
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- Riad Z
- Rialp G
- Richard C
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- Richard JC
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- Ricksten SE
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- Righy C
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- Ristagno G
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- Rivas RF
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- Rivera-Fernandez R
- Rivera-Romero L
- Rizoli S
- Rizos M
- Roasio A
- Robaglia D
- Robert R
- Robles CM
- Roca JM
- Rocha LL
- Rodrigues DP
- Rodrigues NJ
- Rodriguez A
- Rodriguez P
- Rodriguez-Biendicho A
- Rodriguez-Fernandez S
- Rodríguez FG
- Roesthuis L
- Rogero S
- Rolin N
- Rolla F
- Rolland-Debord C
- Romero DG
- Romero I
- Romero JC
- Romero JC
- Romero JC
- Romero JC
- Romeu JD
- Rood PJ
- Ros Martínez J
- Rosario LE
- Rosario LE
- Rosario LE
- Rosario LE
- Rosario LE
- Rosario LE
- Rossetti AO
- Rossi S
- Rossini P
- Rosstalnaya A
- Rota L
- Roth GA
- Rottoli MR
- Rotzel HB
- Rousseau AF
- Routsi C
- Rouw N
- Rouzé A
- Rowlerson A
- Ruberto F
- Rubiera M
- Rubio RJ
- Rudiger A
- Ruffini C
- Ruffini C
- Ruijter A
- Ruiz A
- Ruiz BL
- Ruiz FC
- Ruiz J
- Ruiz-Ramos J
- Ruiz-Rodriguez JC
- Ruiz-Rodríguez JC
- Ruiz-Ruano RDEL
- Runge I
- Runge I
- Runge I
- Rutherford WB
- Rutten AM
- Rydingsward JE
- Saadat F
- Sabetian G
- Sabeļņikovs O
- Sabirov D
- Sadamoto Y
- Sadamoto Y
- Sadamoto Y
- Saeed S
- Saha T
- Saigal S
- Saito M
- Saito N
- Saitou N
- Sakai Y
- Sakieva FI
- Sakuma M
- Sakuraya M
- Sales G
- Salgado DR
- Salluh J
- Sampath S
- Sampath S
- Sampley S
- Sampson D
- Samuels T
- Samy W
- Sanchez A
- Sanchez JA
- Sanchez-Orézzoli MG
- Sandiumenge A
- Sandiumenge A
- Sandroni C
- Sani D
- Santacruz C
- Santana JD
- Santana JD
- Santana MC
- Santana MC
- Santana PS
- Santana PS
- Santana SR
- Santana SR
- Santiago AI
- Santiago AI
- Santos F
- Sanui M
- Sanz ER
- Sanz ER
- Sanz ER
- Sanz ER
- Sanz ER
- Sanz ER
- Sanz NM
- Sanz NM
- Sanz NM
- Sato K
- Savi C
- Savin I
- Savvidou S
- Sawamura A
- Sawamura A
- Sawamura A
- Sawamura A
- Scala S
- Scales DC
- Scanziani E
- Scanziani E
- Schaller SJ
- Schlaepfer P
- Schleifer J
- Schmid RM
- Schmidt M
- Schneider AG
- Schoenenberger JA
- Schortgen F
- Schortgen F
- Schortgen F
- Schröder T
- Schuepbach R
- Schultz MJ
- Schultz MJ
- Schwarz C
- Schwarze S
- Schwerdtfeger K
- Sciurti R
- Scott SH
- Sedlák P
- Seemann R
- Seet E
- Sekhri K
- Seldon T
- Sellés MD
- Sendid B
- Senussi T
- Serati Z
- Serbource-Goguel J
- Sergey S
- Serpytis M
- Serra J
- Sesana G
- Shah A
- Shah H
- Shawaf S
- Shears J
- Sheils MA
- Shekerdemian LS
- Shekerdemian LS
- Sherif H
- Shi ZH
- Shimanskiy V
- Shimony JS
- Shin WJ
- Shin WJ
- Shinotsuka CR
- Shlyk I
- Shu CW
- Shuinotsuka C
- Shum HP
- Shum HP
- Sibley S
- Siddiqui SS
- Sidhu P
- Sigcha MS
- Sigera CS
- Signouret T
- Sigurta A
- Silva G
- Silva JC
- Silva JG
- Silva S
- Similowski T
- Simoes CM
- Simon G
- Simsir M
- Simón IF
- Simón IF
- Simón JM
- Simón JM
- Singer L
- Singer M
- Singer M
- Singer M
- Singh H
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- Sipylaite J
- Sirisena N
- Sirvent JM
- Siu K
- Sjövall F
- Skinner L
- Skrak P
- Skrifvars M
- Skrifvars MB
- Smekal D
- Snelson C
- Snyder AZ
- Sobhanian S
- Soeffker G
- Soilemezi E
- Soilemezi E
- Soilemezi E
- Sokolova E
- Solanki S
- Soler EA
- Solligård E
- Solé-Violán J
- Somhorst P
- Son Y
- Song I
- Song JG
- Song JG
- Song JW
- Song YG
- Song YG
- Sonneville R
- Sosa M
- Sossou A
- Sousa SC
- Soussi S
- Souza VA
- Spadaro S
- Spadaro S
- Spahn DR
- Spatenkova V
- Spazzadeschi A
- Spijkstra JJ
- Spronk PE
- Spronk PE
- Sprung CL
- St George’s University of London
- Stamm J
- Stamouli M
- Stanić R
- Starczewska M
- Staszewsky L
- Stauffert N
- Stella A
- Stephens T
- Stiphout C
- Stocchetti N
- Stocchetti N
- Stougianni M
- Street H
- Stretti F
- Struijs A
- Stubbs C
- Stubbs C
- Student Research Committee - Shiraz University of Medical Sciences
- Stümpfle R
- Stümpfle R
- Su F
- Su L
- Su PL
- Su PL
- Suchomel P
- Suh GJ
- Suh GJ
- Suh GJ
- Suh GY
- Suh JW
- Sullivan E
- Sun WZ
- Sun XM
- Sung D
- Suwanpasu S
- Suzuki S
- Suzuki T
- Swart M
- Sy O
- Sydow K
- Sylla P
- Sáez VC
- Sánchez B
- Sánchez B
- Sánchez EC
- Sánchez MJ
- Sánchez MJ
- Sánchez MJ
- Sánchez MJ
- Sánchez MJ
- Sánchez MJ
- Sánchez PC
- Sánchez PC
- Sánchez-Elvira LA
- Tabatabaei HR
- Tabei SH
- Taccone F
- Taccone FS
- Taccone FS
- Taccone FS
- Taccone FS
- Taccone FS
- Taccone FS
- Taccone FS
- Taggu A
- Taggu A
- Takahashi H
- Takaki S
- Takaki S
- Takeda M
- Takeda M
- Takei T
- Takei T
- Talan L
- Tamura T
- Tanaka H
- Tanaka S
- Tanaka S
- Tane N
- Tang KB
- Tang LK
- Tapia A
- Tapponnier R
- Tapponnier R
- Tapponnier R
- Tarabrin O
- Tarabrin P
- Tavazzi G
- Tavazzi G
- Teboul JL
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- Temprano-Gómez I
- Tena SA
- Tencé N
- Terzi N
- Terzi N
- Terzi N
- Terzi N
- Thabut G
- Thabut G
- Theodorakopoulou M
- Thies P
- Thilakasiri MC
- Thomas B
- Thompson E
- Thévenin D
- Tiainen M
- Timsit JF
- Tirkkonen J
- Tirumala S
- Tjepkema-Cloostermans MC
- Tobar M
- Tofiño AL
- Toh CH
- Tokyo Womens Medical University
- Tomas E
- Tomas E
- Tomic I
- Tominaga N
- Tomás MA
- Tonelotto BF
- Tonetti T
- Tonetti T
- Topcu L
- Tormos P
- Torner MM
- Torner MM
- Torrance HD
- Torrent RL
- Torrent RL
- Torres A
- Torres E
- Torres JC
- Torriglia F
- Torriglia F
- Torriglia F
- Torsvik M
- Tosi F
- Touratier S
- Touw HR
- Toval S
- Tran N
- Trapp O
- Travierso C
- Travieso PM
- Traynor T
- Trefler S
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- Trenado J
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- Trifan B
- Triulzi F
- Troeltzsch M
- Troncoso I
- Trouiller P
- Tseng CJ
- Tsirigotis P
- Tsukahara K
- Tsunano Y
- Tsunoda M
- Tsunoda M
- Tsutui T
- Tucci MR
- Tudor BA
- Tuinman PR
- Tullo L
- Turel M
- Turon R
- Twisk JW
- Törnblom S
- Ugawa T
- Ujike Y
- Ulla DV
- Ullman A
- Unal M
- Urbanaviciute I
- Uriona S
- Urli T
- Usón MC
- Vaahersalo J
- Vaara S
- Vaid N
- Vakalos A
- Valbuena BL
- Valbuena BL
- Valeiras-Valero A
- Vallecoccia MS
- Vallejo-Báez J
- Vallverdu M
- Vallverdu M
- Vallverdú I
- Vallés J
- van den Boogaard M
- van der Heiden ES
- van der Hoeven JG
- van der Hoeven JG
- van der Voort PH
- van Galen T
- van Ieperen SN
- Van Logten T
- van Nes M
- van Putten MJ
- van Thiel RJ
- van Wijk A
- Vandijck D
- Vaneker I
- Vanhuyse F
- Vaporidi K
- Vaquerizo C
- Varas GM
- Varas JL
- Varea MM
- Vargiolu A
- Varma A
- Varpula T
- Vatsik MV
- Vazquez D
- Vedage D
- Vega LM
- Veigas P
- Vela JL
- Velasquez T
- Venkatesan K
- Venn R
- Venn R
- Venot M
- Venrdramin A
- Ventura-Rosado A
- Vergani G
- Verginella F
- Verhaeghe R
- Verhage R
- Vermeir P
- Veronesi M
- Vezzani A
- Vezzani A
- Vianna G
- Viciana R
- Vidal A
- Vidal MV
- Vidal MV
- Viegas E
- Vieillard-Baron A
- Vieira JE
- Viera MA
- Viera MA
- Vigne C
- Villa G
- Villa P
- Villalba D
- Villamizar PR
- Villamizar PR
- Villanova M
- Villard I
- Villarreal E
- Villarreal E
- Vincent B
- Vincent JL
- Vincent JL
- Vincent JL
- Vincent JL
- Vincent JL
- Vincent JL
- Vincent JL
- Vinje LJ
- Vinsonneau C
- Vitaller S
- Vittone F
- Vogelaers D
- Voiriot G
- Volker T
- Volta CA
- Volta CA
- Vondrakova D
- Vondrakova D
- Vondrakova D
- Vong LV
- Vourli S
- Vrettou C
- Vucic M
- Vázquez CF
- Vázquez CF
- Wada T
- Wada T
- Wada T
- Wada T
- Waldauf P
- Wand S
- Wang CH
- Wang H
- Wann SR
- Wann SR
- Wann SR
- Wann SR
- Wathanawatthu T
- Wee S
- Welte T
- Welters I
- Wetz A
- Weyer CM
- White C
- Wiesner O
- Wijayatilake DS
- Wildenberg L
- Wilks M
- Wilson ME
- WIND study group
- WIND study group
- WIND study group
- Winder-Rhodes S
- Witter T
- Wolf M
- Wolff M
- Wong Y
- Wood B
- Wood CA
- Wood D
- Wood M
- Wray J
- Xie Z
- Xini A
- Xini A
- Xiol EA
- Xu M
- Yager T
- Yaguchi A
- Yaguchi A
- Yamaguchi O
- Yamaguchi O
- Yamaguchi Y
- Yamaguchi Y
- Yamamoto H
- Yamamoto N
- Yaman G
- Yamashita K
- Yamazaki A
- Yan WW
- Yan WW
- Yang JH
- Yang JS
- Yang YL
- Yasuda H
- Yatabe T
- Yebenes JC
- Yeh YC
- Yemets H
- Yergaliyeva A
- Yılmaz G
- Yilmazer F
- Yodice P
- Yokoyama M
- Yonis H
- Yonis H
- Yonis H
- Yoon SZ
- Yoruk F
- Yoshida K
- Yoshida T
- Yoshida T
- Yoshida T
- Yoshida T
- Yoshihiro S
- Yoshitake E
- You KM
- Youn AM
- Young A
- Yu KM
- Yumoto T
- Yuzawa J
- Yuzawa J
- Zabaletta WJ
- Zabini D
- Zahorec M
- Zaien I
- Zakynthinos S
- Zanello M
- Zani D
- Zarantonello F
- Zayas B
- Zepeda EM
- Zeroual N
- Zerva L
- Zhang J
- Zhou JC
- Zhou JC
- Zhou JX
- Zhovnir V
- Zibandah N
- Zijlstra F
- Zimmerman J
- Zogheib E
- Zogheib E
- Zogheib E
- Zullino V
- Zwaag J
- Zýková I
- Álvarez JT
- Álvarez-Lerma F
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults.
- Author
- Abarca-Gomez L
- Abdeen ZA
- Abu-Rmeileh NM
- Acosta-Cazares B
- Acuin C
- Adams RJ
- Aekplakorn W
- Afsana K
- Aguilar-Salinas CA
- Agyemng C
- Ahmadvand A
- Ahrens W
- Ajlouni K
- Akhtaeva N
- Al Nsour M
- Al-Hazzaa HM
- Al-Othman AR
- Al-Raddadi R
- AlBuhairan F
- AlDhukai S
- Ali MM
- Ali O
- Alkerwi A
- Alvarez-Pedrerol M
- Aly E
- Amarapurkar DN
- Amouyel P
- Amuzu A
- Andersen LB
- Anderssen SA
- Andrade DS
- Angquist LH
- Anjana RM
- Anselmo Olinto MT
- Aounallah-Skhiri H
- Araujo J
- Arianse I
- Aris T
- Arlappa N
- Arveiler D
- Aryal KK
- Aspelund T
- Assah FK
- Assuncao MCF
- Aung MS
- Avdicova M
- Azevedo A
- Azizi F
- Babu BV
- Bahijri S
- Baker JL
- Balakrishna N
- Bamoshmoosh M
- Banach M
- Bandosz P
- Banegas JR
- Bao KLN
- Bao TQ
- Barbagallo CM
- Barcelo A
- Barkat A
- Barros AJD
- Barros MVG
- Bata I
- Batieha AM
- Batista RL
- Batyrbek A
- Baur LA
- Beaglehole R
- Bebakar WMW
- Ben Romdhane H
- Benedics J
- Benet M
- Bennet JE
- Bennet JE
- Bentham J
- Bernabe A
- Bernotiene G
- Bettiol H
- Bhagyalaxmi A
- Bharadwaj S
- Bhargava SK
- Bhatti Z
- Bhutta ZA
- Bhutta ZA
- Bi H
- Bi Y
- Biehl A
- Bikbov M
- Bilano V
- Bista B
- Bixby H
- Bjelica DJ
- Bjerregaard P
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- Xu H
- Xu L
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- Yan W
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- Ye X
- Yiallouros PK
- Yngve A
- Yoshihara A
- You QS
- Younger-Coleman NO
- Yusof SM
- Yusoff F
- Yusoff MFM
- Yusoff MFM
- Zaccagni L
- Zafiropulos V
- Zainuddin AA
- Zambon S
- Zampelas A
- Zamrazilova H
- Zdrojewski T
- Zeng Y
- Zhao D
- Zhao W
- Zheng W
- Zheng Y
- Zholdin B
- Zhou B
- Zhou M
- Zhu A
- Zhu D
- Zhussupov B
- Zimmermann E
- Publication venue
- Lancet
- Publication date
- 01/01/2017
- Field of study
BACKGROUND: Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. METHODS: We pooled 2416 population-based studies with measurements of height and weight on 128·9 million participants aged 5 years and older, including 31·5 million aged 5-19 years. We used a Bayesian hierarchical model to estimate trends from 1975 to 2016 in 200 countries for mean BMI and for prevalence of BMI in the following categories for children and adolescents aged 5-19 years: more than 2 SD below the median of the WHO growth reference for children and adolescents (referred to as moderate and severe underweight hereafter), 2 SD to more than 1 SD below the median (mild underweight), 1 SD below the median to 1 SD above the median (healthy weight), more than 1 SD to 2 SD above the median (overweight but not obese), and more than 2 SD above the median (obesity). FINDINGS: Regional change in age-standardised mean BMI in girls from 1975 to 2016 ranged from virtually no change (-0·01 kg/m2 per decade; 95% credible interval -0·42 to 0·39, posterior probability [PP] of the observed decrease being a true decrease=0·5098) in eastern Europe to an increase of 1·00 kg/m2 per decade (0·69-1·35, PP>0·9999) in central Latin America and an increase of 0·95 kg/m2 per decade (0·64-1·25, PP>0·9999) in Polynesia and Micronesia. The range for boys was from a non-significant increase of 0·09 kg/m2 per decade (-0·33 to 0·49, PP=0·6926) in eastern Europe to an increase of 0·77 kg/m2 per decade (0·50-1·06, PP>0·9999) in Polynesia and Micronesia. Trends in mean BMI have recently flattened in northwestern Europe and the high-income English-speaking and Asia-Pacific regions for both sexes, southwestern Europe for boys, and central and Andean Latin America for girls. By contrast, the rise in BMI has accelerated in east and south Asia for both sexes, and southeast Asia for boys. Global age-standardised prevalence of obesity increased from 0·7% (0·4-1·2) in 1975 to 5·6% (4·8-6·5) in 2016 in girls, and from 0·9% (0·5-1·3) in 1975 to 7·8% (6·7-9·1) in 2016 in boys; the prevalence of moderate and severe underweight decreased from 9·2% (6·0-12·9) in 1975 to 8·4% (6·8-10·1) in 2016 in girls and from 14·8% (10·4-19·5) in 1975 to 12·4% (10·3-14·5) in 2016 in boys. Prevalence of moderate and severe underweight was highest in India, at 22·7% (16·7-29·6) among girls and 30·7% (23·5-38·0) among boys. Prevalence of obesity was more than 30% in girls in Nauru, the Cook Islands, and Palau; and boys in the Cook Islands, Nauru, Palau, Niue, and American Samoa in 2016. Prevalence of obesity was about 20% or more in several countries in Polynesia and Micronesia, the Middle East and north Africa, the Caribbean, and the USA. In 2016, 75 (44-117) million girls and 117 (70-178) million boys worldwide were moderately or severely underweight. In the same year, 50 (24-89) million girls and 74 (39-125) million boys worldwide were obese. INTERPRETATION: The rising trends in children's and adolescents' BMI have plateaued in many high-income countries, albeit at high levels, but have accelerated in parts of Asia, with trends no longer correlated with those of adults. FUNDING: Wellcome Trust, AstraZeneca Young Health Programme
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy
- Author
- Abdallah J
- Abdul Ghani R
- Abdul Kadir K
- Abdullah R
- Abejuela Z
- Abouglila K
- Abraham O
- Abrahamsen I
- Abraira Munoz Ld
- Abramowitz M
- Abusnana S
- Accini Mendoza Jl
- Acosta I
- Agafyina A
- Agarwal R
- Agarwal Rajiv
- Aggarwal N
- Agra J
- Ahmed F
- Ahuad Guerrero Ra
- Aiello J
- Ainsworth P
- Aizenberg D
- Akiyama H
- Akright L
- Akyea-Djamson A
- Al-Karadsheh A
- Alamartine E
- Alappan R
- Albisu Jp
- Ali N
- Ali Z
- Alicic R
- Allison Dc
- Alvarez Garcia P
- Alvarisqueta A
- Alves da Costa Fa
- Amerena J
- Amigo A
- Amodeo C
- Andreeva V
- Andreotti Turatti La
- Angelescu Lm
- Angelova A
- Anghel V
- Antic S
- Aoki H
- Aquitania G
- Arauz-Pacheco C
- Arcos E
- Arfeen S
- Arif A
- Aronson R
- Arutchelvam V
- Arvind M
- Asano A
- Asmarats Mercadal L
- Atray N
- August P
- Avendano J
- Avram Ri
- Awad A
- Babikova J
- Badat A
- Bajaj H
- Baker J
- Bakris G
- Bakris George
- Barbarash O
- Barna O
- Barnard M
- Barnhill P
- Barranco E
- Barrera C
- Barrios C
- Bartaskova D
- Bartolacci I
- Barton P
- Barysheva O
- Beacom M
- Behara V
- Bellary S
- Belo D
- Belobradkova J
- Bentley-Lewis R
- Benusova O
- Berenguer R
- Berli Ma
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- Yumita W
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- Zanata Petry Tb
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- Zateyshshikov D
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- Zemek S
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- Zhang Hong
- Zhao M
- Zheng H
- Zinman B
- Zinman Bernard
- Zlova T
- Zsom M
- Zub L
- Zykova T
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2019
- Field of study
BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to 300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m 2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
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- Ž
- Ž
- &apos
- Aahlin Ek
- Aamer A
- Aaniana K
- Ababneh A
- Abaliksta T
- Abantanga F
- Abantanga F
- Abbas A
- Abbas M
- Abbasy J
- Abbo O
- Abbo O
- Abbott T
- Abbouch M
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
- Abdel-Aty A
- Abdel-Hameed N
- Abdel-Kader Sm
- Abdel-Wahab Nye
- Abdelaal A
- Abdelaty M
- Abdelazeam Ar
- Abdelazim G
- Abdelaziz Ma
- Abdelbadeai K
- Abdelfatah A
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelhady S
- Abdelhamed R
- Abdelhamid A
- Abdelhaq A
- Abdelkader M
- Abdelkader M
- Abdelkader O
- Abdelkareem A
- Abdelkhalek M
- Abdelmageed E
- Abdelmotaleb I
- Abdelraheim M
- Abdelraouf Am
- Abdelrouf Dm
- Abdelshafy M
- Abdelshakour M
- Abdrabou Ak
- Abdul-Latif S
- Abdulaziz H
- Abdulaziz M
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- Abdulgawad M
- Abdulhakeem Em
- Abdullah Ma
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- Abdullah Nan
- Abdullah Nan
- Abdullahi L
- Abdurrazzaaq A
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- Aboelmagd O
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- Abouzahra A
- Abouzaid A
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- Adelshone A
- Ademuyiwa A
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- Adenekan B
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- Adesanya O
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- Adesina A
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- Adhitama N
- Adil M
- Adisa Ao
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- Al-Mallah A
- Al-Marakby D
- Al-Mousa M
- Al-Nahrawi S
- Al-Obaedi O
- Al-Saqqa S
- Al-Saqqa Sw
- Al-Shammari A
- Al-Slaibi I
- Al-Taher T
- Alaael-Dein S
- Alada M
- Alahmady O
- Alakaloko F
- Alakaloko F
- Alaloul E
- Alamin S
- Alamoudi M
- Alamoudi U
- Albeladi B
- Albiety A
- Aldalaq A
- Aldhafeeri S
- Aledrisy M
- Alexander P
- Alexander P
- Alexandre C
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- Alghamdi A
- Alghamdi B
- Alghamdi M
- Alghamdi Msa
- Algohary O
- Alhabli I
- Alhady K
- Alhammali T
- Alhassan B
- Alhazmi W
- Alhendy M
- Alherz M
- Ali A
- Ali A
- Ali A
- Ali Cdm
- Ali E
- Ali Fm
- Ali H
- Ali S
- Ali Sawew
- Ali Ss
- Ali Tha
- Ali W
- Alihonou T
- Alimi Q
- Alimi Q
- Alis H
- Aliyu H
- Aliyu M
- Aliyu S
- Aljboor K
- Aljiffry M
- Aljiffry M
- Aljohani E
- Aljohani E
- Aljohani S
- Alkaaki A
- Alkammash A
- Alkelani M
- Alkhabbaz D
- Alkhouri M
- Allam M
- Allam M
- Allam Y
- Allegri A
- Allegri A
- Allen Jly
- Allen-Ingabire Jc
- Allott R
- Almallah A
- Almanon Cl
- Almoflihi A
- Almuallem S
- Almy J
- Alnaby Mh
- Alnawam E
- Alnuqaydan Sa
- Alnusairat A
- Alomar In
- Alqahtani E
- Alqahtani S
- Alrahawy M
- Alrajraji M
- Alrifaie A
- AlRowais M
- Alsaggaf M
- Alsaggaf Mu
- Alsaggaf Mu
- Alser Oh
- Alshareef R
- Altaf A
- Altaf A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamini A
- Altarayra M
- Althwainy A
- Altibi A
- Altinel Y
- Altinel Y
- Altoe F
- Altwigry Am
- Altwijri A
- Alvarez Iiz
- Alvi Ar
- Alwafai Mg
- Aly Ak
- Aly Mym
- Alyacoubi S
- Alyahya R
- Alyami R
- Alyami R
- AlYoussef I
- Alzahrani M
- Alzahrani M
- Alzahrani Mna
- Alzayat T
- Aman Nf
- Amandito R
- Amandito R
- Amandito R
- Amandito R
- Ambrona-Zafra D
- Ambrozeviciute V
- Ameen M
- Amer Ma
- Amin Haa
- Amin J
- Amin J
- Amjad M
- Ammar M
- Ammar Ms
- Amoah M
- Amoako J
- Amoako Pt
- Amoako-Boateng M
- Amole I
- Amreia M
- Amreia M
- Anandkumar D
- Anderson D
- Anderson F
- Anderson R
- Anderson-Knight H
- Andersson L
- Andika Ffa
- Andreotti D
- Andress C
- Andriola V
- Ang Yl
- Angelieri D
- Anis E
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Antar S
- Antezana D
- Anthoulakis C
- Anthoulakis C
- Antoniozzi A
- Anwar Aw
- Anwar N
- Anwer W
- Anyanwu Lj
- Anyanwu Lj
- Aonzo P
- Appeadu-Mensah W
- Appiah Ek
- Aql S
- Aquilino F
- Arachchi Pp
- Arachchige Lajj
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- Arango Mcm
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- Arango Mcm
- Arango Mcm
- Araujo Jslr
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- Arnaud Ap
- Arshad Mm
- Arslan E
- Arsyad Hm
- Arthur T
- Arulampalam T
- Aruldas N
- Asaat Ul Razi S
- Asal M
- Asar Yh
- Asare-Bediako K
- Asele Fa
- Ashour A
- Ashour A
- Ashour K
- Ashraf Sf
- Ashtari M
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- Asi F
- Asilah Smd
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- Ata Aaa
- Ata Ay
- Atiyeh A
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- Atobatele K
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- Attard M
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- Attia Am
- Augestad Km
- Aung Kp
- Austraite A
- Aviles S
- Avoka A
- Awad I
- Awad Sa
- Awadallah S
- Awuku-Asabre J
- Ayad S
- Ayandipo O
- Ayandipo Oo
- Aydin Mc
- Ayyar S
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- Aziz Mra
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- Azodo Ia
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- Azzie G
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- Badenjki Ma
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- Badr Mfm
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- Badwi Nm
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- Baillie K
- Baillie K
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- Bakhaidar M
- Baki Be
- Bakr A
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- Baky Fahmy MA
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- Bamford R
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- Bandoh D
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- Barendegere V
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- Barmayehvar B
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- Barreda Lma
- Barrientos Lam
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- Barrios E
- Barrios E
- Barry J
- Basilicò
- Basir Erm
- Bassem M
- Bassit Ka
- Basso Sm
- Basson S
- Basto Caa
- Batt J
- Bautista Acm
- Bautista Acm
- Bayram S
- Beamon M
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- Bedada Ag
- Bediako-Bowan A
- Behar N
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- Beisa V
- Bekhet Ah
- Bekhet Nm
- Beleñ
- Belkouchi A
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- Bello B
- Benammi S
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- Benevento A
- Benger M
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- Benyaiche C
- Bermú
- Bernardo Cg
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- Bertuello I
- Beuran M
- Beuran M
- Beyene R
- Bezzina M
- Bhangu A
- Bhangu A
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- Bhangu A
- Bhargava A
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- Bhat S
- Bhatnagar A
- Bhattacharya S
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- Bhopal Kf
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- Birindelli A
- Birring A
- Bisset C
- Bjö
- Bjö
- Blacker S
- Blackwell J
- Blanco R
- Blanco-Colino R
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- Blencowe N
- Bliksø
- Blower E
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- Boakye-Yiadom K
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- Boddy A
- Bode C
- Bode C
- Bodur S
- Boereboom C
- Boggon A
- Boijsen M
- Bokhari S
- Bonavia K
- Bonavina L
- Bonavina L
- Bond-Smith G
- Bondin J
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- Bondurri A
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- Bonney W
- Borda-Luque G
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- Borg E
- Borg E
- Borin E
- Bortolasi L
- Bortolasi L
- Boshnaq M
- Botero Jam
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- Botto N
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- Bougard H
- Boukhal K
- Bowabsak A
- Bowe R
- Bowley D
- Bowling K
- Bowman C
- Boyce T
- Bré
- Bradulskis S
- Bradulskis S
- Bratu M
- Bratu Mr
- Bratu Rm
- Braungart S
- Bravo Jac
- Bray Ld
- Breistrand M
- Breitenstein S
- Breslin R
- Brincat Sd
- Broch A
- Brogden T
- Brown D
- Brown E
- Brown J
- Brown J
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- Bugaev N
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- Buisson P
- Bukari M
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- Burger S
- Burmistrovas A
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- Bustangi N
- Butt Mt
- Cabrera Ccrr
- Cacurri A
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- Cahill R
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- Camacho R
- Cameron B
- Camilleri Gm
- Camilleri-Brennan J
- Camilleri-Brennan J
- Camilleri-Brennan Jf
- Campagnaro T
- Canto Md
- Capito C
- Capleton P
- Carabott K
- Cardozo Jt
- Cardozo Ram
- Careta Mc
- Carlucci M
- Carmona Jm
- Carneros Vj
- Carpio J
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- Cassar K
- Castillo Vdp
- Castro Mr
- Catani M
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- Caydiid H
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- Cengiz Y
- Cengiz Y
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- Chachulski W
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- Chai Fy
- Chambers A
- Chambers A
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- Chan L
- Chan Tk
- Chan Xw
- Chan Z
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- Chang Ky
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- Chapman Sj
- Charles A
- Cheah Aez
- Chen Cy
- Chen Jhc
- Chen Ky
- Chen Tl
- Chenn R
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- Chetta N
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- Chew Ls
- Chhabra S
- Chibuye C
- Chidambaram S
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- Chin Yr
- Chiong Jac
- Chiong Jac
- Chiu S
- Chiu S
- Chiu Smy
- Choi J
- Choi P
- Chong Bfhk
- Chong Cl
- Chong Cl
- Chong Cl
- Chong Cs
- Chong Hy
- Chong Hy
- Choudhry A
- Chow Cyn
- Chowdhury A
- Chowdhury D
- Chu K
- Chun A
- Chun T
- Chung Kj
- Chung S
- Ciccioli E
- Cirocchi R
- Ciubotaru C
- Claire R
- Clarissa A
- Clark Dj
- Clark T
- Clegg-Lampety Jn
- Clegg-Lamptey Jn
- Clement Kd
- Clements Jm
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- Cohen F
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- Coletti M
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- Conci S
- Confalonieri G
- Conlon Kc
- Connor K
- Connor K
- Contreras E
- Contreras-Vergara Al
- Coomber R
- Coompson Cl
- Corbellini C
- Corbellino M
- Cornick J
- Coronel J
- Correa Jc
- Corro-Diaz S
- Costa C
- Costa-Maia J
- Costa-Maia J
- Costas-Chavarri A
- Costas-Chavarri A
- Courboin E
- Court E
- Cox D
- Cox M
- Coyoy-Gaitan O
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- Cross K
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- Cruz H
- Cucumazzo S
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- Currow C
- Cury Adl
- Dé
- D&apos
- D&apos
- D&apos
- D&apos
- D&apos
- D&apos
- Da Silva LA
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- Dabbour K
- Dabessa D
- Dablouk M
- Dablouk Mo
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- Dahy A
- Dainius E
- Dakubo J
- Dalli J
- Dally C
- Dambrauskas Z
- Dambrauskas Z
- Dan I
- Danelli P
- Daniels I
- Daniyan M
- Danys D
- Dao W
- Daqeeq A
- Dar M
- Dar W
- Dardenne S
- Darweesh M
- Darwish Ak
- Das A
- Das K
- Das S
- Dasari M
- Dashnyam E
- Dassah V
- Datta U
- Davenport R
- Davies J
- Davies R
- Davor A
- Dawnay G
- Dawood K
- Dawoud H
- Dayie M
- De Boni D
- De Bono P
- De Bono P
- De Castro Segundo LCB
- De Franciscis S
- De Freitas AVC
- De La Medina AR
- de Leó
- De Leon MZP
- De Leon MZP
- de Lima CVB
- De Luca E
- De Marco P
- De Sousa AV
- Deal R
- Dean R
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- Debrah S
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- Decker E
- Decoud Hp
- Dedekind B
- Dedey F
- Deichsel F
- Del Basso C
- Del Pilar Paucar A
- Delforge X
- Delgado Jm
- Delgado Msftl
- Dell A
- Dempster E
- Denewar A
- Depalma N
- Deputy M
- Der Y
- Dervenis C
- Despotidis V
- Desta S
- Deutschmann P
- Devadasar Gh
- Dharamshi Ha
- Dhillon D
- Di Franco F
- Di Martino N
- Di Saverio S
- Di Saverio S
- Diab A
- Diaconescu B
- Diaconescu Ib
- Dias S
- Diaz-Jover P
- Diaz-Zorrilla C
- Dick L
- Dickfos M
- Dickson L
- Dijan E
- Dimech T
- Din F
- Dindyal S
- Dindyal S
- Dissanayake T
- Djivoh F
- Domini E
- Domini E
- Donnelly P
- Donoghue D
- Dorani Rmnr
- Dorismé
- Dos Santos DV
- Dossou F
- Doughan S
- Doughty J
- Dousset B
- Dragatas D
- Drake Tm
- Drake Tm
- Driscoll A
- Drungilas M
- Du Plessis D
- du Plooy F
- Du Toit F
- Duane T
- Dubois A
- Dueñ
- Duffy L
- Duhoranenayo D
- Duinhouwer L
- Dulskas A
- Durand Sya
- Dwydar A
- Ebdewi H
- Ebidy M
- Ebidy Mm
- Ebrahim Os
- Eduard P
- Edwards J
- Edye M
- Eid Mm
- Eisner L
- Ekow M
- El Ashal G
- El Dahab AA
- El Deen KN
- El Galeel AA
- El Gendy NH
- El Gendy A
- El Halawany M
- El Hameed OSA
- El Hamid NA
- El Jamassi A
- El Kashash A
- El Kholy A
- El Magd AA
- El Mesery S
- El Salam YA
- El Sayed GS
- El Sayed IM
- El Shoura Y
- El Slam MA
- El-Badawy Ha
- El-Dien Ks
- El-Dien Ks
- El-Din Ra
- El-Din Sa
- El-Gizawy E
- El-Hamouly As
- El-Kashef H
- El-Latif Nka
- El-Ma&apos
- El-Rabaa S
- El-Sagheer N
- El-Salam Fa
- El-Sawy A
- El-Sehily A
- El-Shahat Ns
- El-Sheemy H
- El-Taher E
- Elabdin Hz
- Elashmawy M
- Elashry R
- Elazab A
- Elazayem Aa
- Elazoul M
- Elbanby E
- Elbanby Es
- Elbatahgy A
- Elbe P
- Elbermawy M
- Elbisomy Kh
- Eldafrawy M
- Eldamaty L
- Eldeeb Az
- Eldeen Ea
- Eldin Mab
- Elebute O
- Elebute O
- Elena G
- Elfarargy A
- Elfeki H
- Elfeki H
- Elfiky M
- Elfil M
- Elfouly N
- Elfouly N
- Elfouly Y
- Elfouly Y
- Elgebaly A
- Elgendy Ah
- Elgendy Fi
- Elgheriany M
- Elhadad A
- Elhadary Nm
- Elhadry S
- Elhalawany E
- Elhamouly S
- Elhelbawy Ms
- Elhendawy A
- Elhendawy Aoa
- Elhoseny G
- Elhusseiny Aae
- Elkadsh I
- Elkady F
- Elkelany A
- Elkelany A
- Elkelany A
- Elkelany A
- Elkhadrawi M
- Elkhalek Ea
- Elkholy A
- Elkholy Ss
- Elkolaly Ss
- Elkorashy Am
- Ellison Q
- Elmashala A
- Elmasry M
- Elmelegy R
- Elmihy S
- Elnagar A
- Elnajjar Ma
- Elnemr Ae
- Elrasoul Ya
- Elrazek Aa
- Elsabbagh N
- Elsameea Aa
- Elsawahly Dme
- Elsawy A
- Elsayed M
- Elsayed M
- Elsayed N
- Elsayed Nar
- Elsayed Zm
- Elsebaaye Ao
- Elsehimy M
- Elsemelawy R
- Elshaar M
- Elshaer K
- Elshaer M
- Elshaer M
- Elshafay Ae
- Elshami M
- Elshanwany S
- Elsharkawy Aa
- Elsheikh S
- Elsherbiney S
- Elsherbiny As
- Elsherif Fa
- Elshobary M
- Elsiddig M
- Elsobky S
- Elsorogy Deaa
- Elwaey A
- Elwakil H
- Elwan A
- Elwan A
- Elwy E
- Elzahed N
- Elzayat I
- Elzayat M
- Elzayyat I
- Elzowawi F
- Emadeldin D
- Emadeldin H
- Emara E
- Emile S
- Eng C
- English W
- Esam A
- Escobar Eg.
- Espin-Basany E
- Espinoza F
- Espinoza Kt
- Espinoza Kt
- Essam A
- Essam Aa
- Essam M
- Essoun S
- Esteban E
- Estee Mm
- Estupinian S
- Etchill E
- Etchill E
- Etienne S
- Etman M
- Etwire V
- Evajelista Cv
- Evans D
- Evans E
- Eysa A
- Eyssartier E
- Ezzat E
- Ezzat T
- Faboya O
- Faccincani R
- Fadel A
- Fahiem A
- Fahim M
- Fahy C
- Fairfield C
- Fairfield C
- Fairfield C
- Fakher R
- Falaschi F
- Falco N
- Falzon M
- Farag A
- Farag S
- Farah A
- Farahat Mm
- Faraz A
- Fares M
- Farfan Esf
- Farhad M
- Farhan-Alanie Mmh
- Farhangmehr N
- Farinella E
- Farmakis K
- Farooq T
- Farouk Sam
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy Am
- Fattah Aa
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe Co
- Fergany A
- Fergusson Sj
- Fergusson Sj
- Fergusson Sj
- Fermani C
- Fermani Cg
- Ferná
- Fernandes C
- Fernandez-Bueno F
- Fernandez-Vega L
- Ferousis C
- Ferreira Sak
- Ferrero E
- Fievet L
- Filatau A
- Findlay-Cooper K
- Firdouse M
- Firdouse M
- Firdouse M
- Firwana A
- Fitsum A
- Fitzgerald Je
- Florez Ljg
- Foco M
- Fok Cyj
- Fontana T
- Foo Cc
- Forlin L
- Forno W
- Fouad A
- Fouad D
- Fouad D
- Fourcade L
- Fowler Aj
- Fozard T
- Fozard T
- Frade F
- Fraga Gp
- Franco H
- Francois P
- Francois-Coridon H
- Francone E
- Freitas Av
- Frey D
- Frisk B
- Fuentes-Rivera L
- Fujii F
- Furqan Mm
- Gü
- Gü
- Gaafar S
- Gaarder T
- Gad A
- Gad Mo
- Gadelkarim M
- Gadhvi V
- Gado A
- Gaiž
- Gaignard E
- Gaignard E
- Gala T
- Gala T
- Galiqi G
- Galleano R
- Gallo G
- Galloway S
- Galvez Cp
- Gamal D
- Gamal E
- Gamal H
- Gamal S
- Gamaly E
- Gamil D
- Gan C
- Gan Yy
- Gani Ma
- Garaycochea O
- Garcí
- Garcí
- Garcí
- Garcia-Florez L
- Garcia-Marin Ja
- Garcia-Perez Jm
- Garland A
- Gash K
- Gash K
- Gash K
- Gastaldi P
- Gasteratos K
- Gaujoux S
- Gavagna L
- Gbessi Dg
- Gemeah M
- Gemenetzis G
- Gemenetzis G
- George R
- Germanos S
- Germanos S
- Gerosa A
- Gerosa A
- Geuoshy A
- Ghaben A
- Ghandora N
- Ghanem A
- Ghanem E
- Ghanem S
- Ghanem S
- Ghannam M
- Gharib A
- Gharib A
- Ghazy Aa
- Gheith A
- Ghetia M
- Ghetia M
- Ghonaim Ma
- Ghoneem M
- Ghoneim O
- Giacci L
- Giardino Fr
- Giavarini L
- Giglio Mc
- Gilbert R
- Gilbert Rw
- Giles J
- Gillespie M
- Gimzewska M
- Giraldo Rsr
- Giuliani S
- Giuliani S
- Giuriato Tf
- Gkiokas G
- Glasbey J
- Glasbey J
- Glasbey Jc
- Glasbey Jc
- Glover Te
- Glover-Addy H
- Glynn M
- Gobin N
- Gobin N
- Goh Cc
- Goh Cc
- Goh W
- Gohar Meam
- Gokani S
- Goldin E
- Golding D
- Gomaa A
- Gomah M
- Gonzalez M
- Gonzalez Sc
- Goodstein M
- Gosling S
- Gosling Sg
- Gouda A
- Gould L
- Gouldthorpe C
- Gouvas N
- Gouws J
- Graffeille V
- Graffieille V
- Gran M
- Grandinetti Pp
- Grant A
- Grasset E
- Grasset E
- Grassi V
- Gratton R
- Gravante G
- Gravante G
- Gray D
- Grech N
- Green N
- Grella Mg
- Gribauskaite J
- Griffiths E
- Griffiths E
- Griffiths M
- Grima T
- Grisin E
- Grizhja B
- Grobler Dc
- Grosos C
- Grossart C
- Guasti Bpsj
- Gudal A
- Gudal A
- Gudal A
- Gudlaugsdottir K
- Guevara R
- Guglielmo V
- Gui D
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- Publication venue
- 'Wiley'
- Publication date
- 27/11/2018
- Field of study
Background
End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection.
Methods
This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model.
Results
In total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6·9 per cent) from low-HDI, 254 (15·5 per cent) from middle-HDI and 1268 (77·6 per cent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57·5, 40·9 and 35·4 per cent; P < 0·001) and subsequent use of end colostomy (52·2, 24·8 and 18·9 per cent; P < 0·001) in low- compared with middle- and high-HDI settings. The association with colostomy use in low-HDI settings persisted (odds ratio (OR) 3·20, 95 per cent c.i. 1·35 to 7·57; P = 0·008) after risk adjustment for malignant disease (OR 2·34, 1·65 to 3·32; P < 0·001), emergency surgery (OR 4·08, 2·73 to 6·10; P < 0·001), time to operation at least 48 h (OR 1·99, 1·28 to 3·09; P = 0·002) and disease perforation (OR 4·00, 2·81 to 5·69; P < 0·001).
Conclusion
Global differences existed in the proportion of patients receiving end stomas after left-sided colorectal resection based on income, which went beyond case mix alone