549 research outputs found
Discovering context-specific relationships from biological literature by using multi-level context terms
- Author
- Publication venue
- BioMed Central
- Publication date
- 01/01/2012
- Field of study
<p>Abstract</p> <p>Background</p> <p>The Swanson's ABC model is powerful to infer hidden relationships buried in biological literature. However, the model is inadequate to infer relations with context information. In addition, the model generates a very large amount of candidates from biological text, and it is a semi-automatic, labor-intensive technique requiring human expert's manual input. To tackle these problems, we incorporate context terms to infer relations between AB interactions and BC interactions.</p> <p>Methods</p> <p>We propose 3 steps to discover meaningful hidden relationships between drugs and diseases: 1) multi-level (gene, drug, disease, symptom) entity recognition, 2) interaction extraction (drug-gene, gene-disease) from literature, 3) context vector based similarity score calculation. Subsequently, we evaluate our hypothesis with the datasets of the "Alzheimer's disease" related 77,711 PubMed abstracts. As golden standards, PharmGKB and CTD databases are used. Evaluation is conducted in 2 ways: first, comparing precision of the proposed method and the previous method and second, analysing top 10 ranked results to examine whether highly ranked interactions are truly meaningful or not.</p> <p>Results</p> <p>The results indicate that context-based relation inference achieved better precision than the previous ABC model approach. The literature analysis also shows that interactions inferred by the context-based approach are more meaningful than interactions by the previous ABC model.</p> <p>Conclusions</p> <p>We propose a novel interaction inference technique that incorporates context term vectors into the ABC model to discover meaningful hidden relationships. By utilizing multi-level context terms, our model shows better performance than the previous ABC model.</p
Searching the protein structure database for ligand-binding site similarities using CPASS v.2
- Author
- A Herraez
- A Mercier Kelly
- A Schneider
- A Stark
- A Stark
- Adam Caprez
- AE Todd
- Ashu Guru
- B Rost
- C Dessimoz
- CD Livingstone
- D Petrey
- D Watson James
- David Swanson
- EF Pettersen
- G Ausiello
- G Lopez
- H Hegyi
- HM Berman
- I Friedberg
- I Sfiligoi
- JA Gerlt
- Jaime L Stark
- JD Blake
- Jennifer C Copeland
- JL Stark
- K Park
- KA Mercier
- L Lo Conte
- M Litzkow
- MD Shortridge
- MJ Zvelebil
- ND Gold
- R Kolodny
- R Pordes
- R Powers
- R Powers
- R Powers
- RL Tatusov
- Robert Powers
- S Henikoff
- S Henikoff
- SA Cammer
- SJ Hubbard
- T Triplet
- V Sangar
- W Zhang
- YJ Huang
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
<p>Abstract</p> <p>Background</p> <p>A recent analysis of protein sequences deposited in the NCBI RefSeq database indicates that ~8.5 million protein sequences are encoded in prokaryotic and eukaryotic genomes, where ~30% are explicitly annotated as "hypothetical" or "uncharacterized" protein. Our Comparison of Protein Active-Site Structures (CPASS v.2) database and software compares the sequence and structural characteristics of experimentally determined ligand binding sites to infer a functional relationship in the absence of global sequence or structure similarity. CPASS is an important component of our Functional Annotation Screening Technology by NMR (FAST-NMR) protocol and has been successfully applied to aid the annotation of a number of proteins of unknown function.</p> <p>Findings</p> <p>We report a major upgrade to our CPASS software and database that significantly improves its broad utility. CPASS v.2 is designed with a layered architecture to increase flexibility and portability that also enables job distribution over the Open Science Grid (OSG) to increase speed. Similarly, the CPASS interface was enhanced to provide more user flexibility in submitting a CPASS query. CPASS v.2 now allows for both automatic and manual definition of ligand-binding sites and permits pair-wise, one versus all, one versus list, or list versus list comparisons. Solvent accessible surface area, ligand root-mean square difference, and Cβ distances have been incorporated into the CPASS similarity function to improve the quality of the results. The CPASS database has also been updated.</p> <p>Conclusions</p> <p>CPASS v.2 is more than an order of magnitude faster than the original implementation, and allows for multiple simultaneous job submissions. Similarly, the CPASS database of ligand-defined binding sites has increased in size by ~ 38%, dramatically increasing the likelihood of a positive search result. The modification to the CPASS similarity function is effective in reducing CPASS similarity scores for false positives by ~30%, while leaving true positives unaffected. Importantly, receiver operating characteristics (ROC) curves demonstrate the high correlation between CPASS similarity scores and an accurate functional assignment. As indicated by distribution curves, scores ≥ 30% infer a functional similarity. Software URL: <url>http://cpass.unl.edu</url>.</p
Synaptic tagging and capture in the living rat
- Author
- A Gasbarri
- A Govindarajan
- AV Sharma
- CG Gross
- CM Alberini
- CM O'Carroll
- CM O’Carroll
- CR Bramham
- D Moncada
- DG Amaral
- EL Bienenstock
- F Ballarini
- G Buzsaki
- G Riedel
- GG Turrigiano
- H Hassan
- I Bethus
- JD Richter
- JE Lisman
- JL Swanson-Park
- JM Alarcon
- JW Rudy
- JZ Young
- K McNair
- K Wanisch
- KC Martin
- KC Martin
- LS Leung
- M Doyle
- M Hubener
- MA Sutton
- N Lemon
- N Meiri
- P Mullany
- R Anwyl
- R Fonseca
- RD Hawkins
- RL Redondo
- RL Redondo
- S Frey
- S Laurberg
- S Sajikumar
- S Sajikumar
- SH Wang
- SI Cohen-Matsliah
- SJ Martin
- SM Dudek
- T Kaibara
- TJ O'Dell
- TN Wiesel
- U Frey
- U Frey
- U Frey
- U Stäubli
- WB Smith
- WC Abraham
- Y Lu
- Z Qi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2012
- Field of study
In isolated hippocampal slices, decaying long-term potentiation can be stabilized and converted to late long-term potentiation lasting many hours, by prior or subsequent strong high-frequency tetanization of an independent input to a common population of neurons—a phenomenon known as ‘synaptic tagging and capture’. Here we show that the same phenomenon occurs in the intact rat. Late long-term potentiation can be induced in CA1 during the inhibition of protein synthesis if an independent input is strongly tetanized beforehand. Conversely, declining early long-term potentiation induced by weak tetanization can be converted into lasting late long-term potentiation by subsequent strong tetanization of a separate input. These findings indicate that synaptic tagging and capture is not limited to in vitro preparations; the past and future activity of neurons has a critical role in determining the persistence of synaptic changes in the living animal, thus providing a bridge between cellular studies of protein synthesis-dependent synaptic potentiation and behavioural studies of memory persistence
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alda Junior WL
- Alexander J
- Aliev T
- Almeida N
- Alver B
- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Anderson M
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Anjos TS
- Antonelli L
- Antunes JR
- Antunovic Z
- Apanasevich L
- Apollinari G
- Appelt E
- Apresyan A
- Aranyi A
- Arce P
- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
- Arisaka K
- Arneodo M
- Arora S
- Asawatangtrakuldee C
- Asghar MI
- Askew A
- Assran Y
- Ata M
- Atac M
- Atramentov O
- Attikis A
- Auffray E
- Autermann C
- Auzinger G
- Avdeeva E
- Avery P
- Avetisyan A
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzolini V
- Azzurri P
- Baarmand MM
- Babb J
- Bacchetta N
- Bachtis M
- Baden A
- Baeni L
- Baesso P
- Baffioni S
- Bagliesi G
- Bai Y
- Baillon P
- Bainbridge R
- Bakhshiansohi H
- Bakirci MN
- Bakken JA
- Balazs M
- Ball AH
- Ball G
- Ban Y
- Banerjee S
- Banerjee S
- Bansal S
- Banzuzi K
- Barbagli G
- Barberis E
- Barbone L
- Bardak C
- Barfuss AF
- Bargassa P
- Barge D
- Baringer P
- Barker A
- Barnes VE
- Barnett BA
- Barney D
- Barone L
- Barrett M
- Bartalini P
- Barth C
- Basegmez S
- Basso L
- Battilana C
- Baty C
- Bauer G
- Bauerdick LAT
- Baumgartel D
- Baur U
- Bayshev I
- Bazterra VE
- Bean A
- Beauceron S
- Beaudette F
- Beaupere N
- Bedjidian M
- Beernaert K
- Behrenhoff W
- Behrens U
- Belforte S
- Beliy N
- Belknap D
- Bell AJ
- Bell KW
- Bellan P
- Bellan R
- Bellato M
- Bellinger JN
- Belotelov I
- Belyaev A
- Belyaev A
- Benaglia A
- Bencze G
- Bendavid J
- Benedetti D
- Benelli G
- Benhabib L
- Beni N
- Benucci L
- Benussi L
- Benvenuti AC
- Beranek S
- Beretvas A
- Bergauer T
- Berger J
- Bergholz M
- Beri SB
- Bernardes CA
- Bernardini J
- Bernet C
- Berry D
- Berry E
- Berryhill J
- Bertl W
- Berzano U
- Besancon M
- Betchart B
- Bethani A
- Betts RR
- Beuselinck R
- Bhat PC
- Bhatnagar V
- Bhattacharya S
- Bhattacharya S
- Bhatti A
- Bialas W
- Bialkowska H
- Bian JG
- Bianchi G
- Bianchini L
- Bianco S
- Biasini M
- Biino C
- Bilei GM
- Bilin B
- Bilinskas MJ
- Bilki B
- Bilmis S
- Biselli A
- Bisello D
- Bitioukov S
- Blekman F
- Blobel V
- Bloch D
- Bloch I
- Bloch P
- Bloom K
- Bluj M
- Blumenfeld B
- Blyweert S
- Bobrovskyi S
- Boccali T
- Bocci A
- Bochenek J
- Bodek A
- Bodin D
- Boimska B
- Boldizsar L
- Bolla G
- Bolognesi S
- Bolton T
- Bonacorsi D
- Bonato A
- Bondu O
- Bontenackels M
- Boos E
- Bornheim A
- Borras K
- Borrello L
- Bortignon P
- Bortoletto D
- Bose S
- Bose T
- Bostock F
- Botta C
- Boudoul G
- Boulahouache C
- Boumediene D
- Bourilkov D
- Boutemeur M
- Boutle S
- Braibant-Giacomelli S
- Branca A
- Branson JG
- Breedon R
- Breto G
- Breuker H
- Brew C
- Brigliadori L
- Brigljevic V
- Brinkerhoff A
- Broccolo G
- Brochero Cifuentes JA
- Brom JM
- Brona G
- Brooke JJ
- Broutin C
- Brown RM
- Brownson E
- Brun H
- Bruno G
- Bryer AG
- Buchmann MA
- Buchmuller O
- Bunkowski K
- Bunn J
- Buontempo S
- Burgmeier A
- Burkett K
- Busson P
- Busza W
- Butler JN
- Butler PH
- Butt J
- Butz E
- Bylsma B
- Cabrera A
- Cabrillo IJ
- Caebergs T
- Cakir A
- Calabria C
- Calderon De La Barca Sanchez M
- Calderon A
- Cali IA
- Calligaris L
- Callner J
- Calvert B
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- Campagnari C
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- Camporesi T
- Capiluppi P
- Caponeri B
- Cappello G
- Cardaci M
- Carlin R
- Carlsmith D
- Carrillo Moreno S
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- Cartiglia N
- Carvalho W
- Casal B
- Casimiro Linares E
- Castaldi R
- Castello R
- Castilla-Valdez H
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- Caudron J
- Caulfield M
- Cavallari F
- Cavallo FR
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- Cavanaugh R
- Ceard L
- Ceballos GG
- Cepeda M
- Cerati GB
- Cerci DS
- Cerci S
- Cerizza G
- Cerminara G
- Cerrada M
- Chabert EC
- Chadwick M
- Chakaberia I
- Chamizo Llatas M
- Chan M
- Chang P
- Chang S
- Chang YH
- Chang YH
- Chang YW
- Chanon N
- Chao Y
- Charaf O
- Charlot C
- Chasco M
- Chasserat J
- Chatrchyan S
- Chatterjee A
- Chauhan S
- Checchia P
- Chen GM
- Chen HS
- Chen J
- Chen KF
- Chen KH
- Chen M
- Chen Y
- Chen Z
- Cherepanov V
- Chertok M
- Chetluru V
- Cheung HWK
- Chhibra SS
- Chierici R
- Chiochia V
- Chiorboli M
- Chlebana F
- Cho Y
- Choi M
- Choi S
- Choi Y
- Choi YK
- Chou JP
- Choudhary BC
- Choudhury RK
- Choudhury S
- Christiansen T
- Chuang SH
- Chung J
- Chung YS
- Chwalek T
- Ciesielski R
- Cihangir S
- Cimmino A
- Cipriano PMR
- Cirino G
- Cittolin S
- Ciulli V
- Civinini C
- Claes DR
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- Clarida W
- Clement E
- Clerbaux B
- Cline D
- CMS Collaboration
- Cockerill DJA
- Codispoti G
- Colafranceschi S
- Colaleo A
- Cole JE
- Colino N
- Collard C
- Colling D
- Conetti S
- Contardo D
- Conte E
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- Conway J
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- Cooper SI
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- Cornelis T
- Correa Martins Junior M
- Cortezon EP
- Cossutti F
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- Coughlan JA
- Cousins R
- Covarelli R
- Cox B
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- Creanza D
- Cremaldi LM
- Cripps N
- Cuevas J
- Cuffiani M
- Cumalat JP
- Cuplov V
- Cure B
- Cushman P
- Cussans D
- Custodio A
- Cutajar M
- Cutts D
- Cwiok M
- Czellar S
- D'Agnolo RT
- D'Alessandro R
- D'Alfonso M
- D'Enterria D
- D'Hondt J
- Da Costa EM
- Daci N
- Dahmes B
- Dahms T
- Dallavalle GM
- Damgov J
- Damiao DD
- Dammann D
- Danielson T
- Das S
- Daskalakis G
- Dasu S
- Daubie E
- Dauncey P
- David A
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- de Cassagnac RG
- De Cosa A
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- De Guio F
- De Jeneret JD
- De La Cruz B
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- De Lentdecker G
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- de Monchenault GH
- De Oliveira Martins C
- De Palma M
- De Roeck A
- de Troconiz JF
- De Visscher S
- De Wolf EA
- Deisher A
- Deiters K
- Dejardin M
- del Arbol PMR
- Del Re D
- Delaere C
- Delgado Peris A
- Deliomeroglu M
- Dell'Orso R
- Della Negra M
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- Demina R
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- Denegri D
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- Depasse P
- Dermenev A
- Dero V
- Dhingra N
- Di Giovanni GP
- Di Guida S
- Di Marco E
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- Dias FA
- Diemoz M
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- Dimitrov A
- Dinardo ME
- Dirkes G
- Dissertori G
- Dittmar M
- Djordjevic M
- Dobrzynski L
- Dobson M
- Dobur D
- Doesburg R
- Dogangun O
- Dolen J
- Dominguez Vazquez D
- Dominguez A
- Dominik W
- Don CKK
- Dorigo T
- Dorney B
- Doroba K
- Dozen C
- Draeger J
- Dragicevic M
- Dragoiu C
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- Dremin I
- Drouhin F
- Drozdetskiy A
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- Duarte J
- Dubinin M
- Dudero PR
- Dudko L
- Duenser M
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- Duggan D
- Dumanoglu I
- Dupont-Sagorin N
- Duric S
- Duris J
- Durkin LS
- Duru F
- Dutta D
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- Dutta V
- Dzelalija M
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- Eartly DP
- Eckerlin G
- Ecklund KM
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- Edelmaier CJ
- Eerola P
- Efron J
- Eggert N
- Ekmedzic M
- El Mamouni H
- Elgammal S
- Elliott-Peisert A
- Ellison J
- Elmer P
- Elvira VD
- Enderle H
- Engh D
- Eno SC
- Epshteyn V
- Erbacher R
- Erdmann M
- Erdmann W
- Erfle J
- Erhan S
- Ero J
- Erofeeva M
- Ershov A
- Esen S
- Eshaq Y
- Eskut E
- Etesami SM
- Eugster J
- Eusebi R
- Evangelou I
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- Everaerts P
- Everett A
- Evstyukhin S
- Fabbri F
- Fabbri F
- Fabbricatore P
- Fabbro B
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- Faccioli P
- Fahim A
- Falkiewicz A
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- Fanfani A
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- Fantasia C
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- Fassi F
- Faure JL
- Favaro C
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- Fay J
- Fedi G
- Fehling D
- Feindt M
- Felcini M
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- Ferapontov A
- Ferencek D
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- Ferguson W
- Fernandez Bedoya C
- Fernandez Menendez J
- Fernandez Perez Tomei TR
- Fernandez Ramos JP
- Fernandez M
- Ferrando A
- Ferri F
- Ferro C
- Field RD
- Finger M
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- Fiore L
- Fiorendi S
- Fiori F
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- Gamsizkan H
- Ganguly S
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- Gerber CE
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- Gerwig H
- Geurts FJM
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- Grigelionis I
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- Grishin V
- Gritsan AV
- Grogg KS
- Gronberg J
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- Grundler U
- Grunewald M
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- Gude A
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- Guthoff M
- Gutsche O
- Gyun D
- Haas J
- Hackstein C
- Hadjiiska R
- Hadley NJ
- Hagopian S
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- Haguenauer M
- Hahn KA
- Hajdu C
- Halkiadakis E
- Hall G
- Hall-Wilton R
- Halyo V
- Hammad GH
- Hammer J
- Han J
- Hanlon J
- Hansen M
- Hanson G
- Harder K
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- Harkonen J
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- Hartl C
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- Harvey J
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- Hatakeyama K
- Hatherell Z
- Hauk J
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- Heath GP
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- Hebbeker T
- Hebda P
- Hegeman J
- Hegner B
- Heidemann C
- Heikkinen A
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- Heister A
- Hektor A
- Held H
- Heltsley B
- Henderson C
- Heo SG
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- Heredia-de La Cruz I
- Hermanns T
- Hernandez JM
- Herndon M
- Herve A
- Hesari H
- Heyburn B
- Hidas D
- Hidas P
- Hildreth M
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- Hindrichs O
- Hinzmann A
- Hirosky R
- Hirschauer J
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- Hobson PR
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- Hoehle F
- Hoeing RS
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- Hoermann N
- Hoffmann HF
- Hoffmann KH
- Hofman DJ
- Hohlmann M
- Hollar J
- Hollingsworth M
- Holzner A
- Honc S
- Hong B
- Hooberman B
- Hoorani HR
- Hopkins W
- Horisberger R
- Horvath D
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- Hou W-S
- Houtz R
- Hreus T
- Hrubec J
- Hsiung Y
- Hu G
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- Huang XT
- Hugon J
- Hunt A
- Iaselli G
- Iashvili I
- Iaydjiev P
- Ignatenko M
- Iii RPK
- Iiyama Y
- Iles G
- Ille B
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- Ingram Q
- Innocente V
- Iorio AOM
- Isildak B
- Issah M
- Ivanov A
- Ivanov Y
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- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
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- Zeinali M
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- Zoeller MH
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- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Measurement of the Bottom-Strange Meson Mixing Phase in the Full CDF Data Set
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- Warburton
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- Wicklund
- Wicklund
- Wilbur
- Williams
- Wilson
- Wilson
- Winer
- Wittich
- Wolbers
- Wolfe
- Wright
- Wu
- Wu
- X.
- Y.
- Y.
- Y.
- Y.
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- Y.
- Y.
- Y.
- Y.C.
- Y.C.
- Y.D.
- Y.J.
- Y.K.
- Y.S.
- Yamamoto
- Yamato
- Yang
- Yang
- Yang
- Yao
- Yeh
- Yi
- Yoh
- Yorita
- Yoshida
- Yu
- Yu
- Yu
- Yun
- Z.
- Zanetti
- Zeng
- Zhou
- Zucchelli
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
We report a measurement of the bottom-strange meson mixing phase \beta_s
using the time evolution of B0_s -> J/\psi (->\mu+\mu-) \phi (-> K+ K-) decays
in which the quark-flavor content of the bottom-strange meson is identified at
production. This measurement uses the full data set of proton-antiproton
collisions at sqrt(s)= 1.96 TeV collected by the Collider Detector experiment
at the Fermilab Tevatron, corresponding to 9.6 fb-1 of integrated luminosity.
We report confidence regions in the two-dimensional space of \beta_s and the
B0_s decay-width difference \Delta\Gamma_s, and measure \beta_s in [-\pi/2,
-1.51] U [-0.06, 0.30] U [1.26, \pi/2] at the 68% confidence level, in
agreement with the standard model expectation. Assuming the standard model
value of \beta_s, we also determine \Delta\Gamma_s = 0.068 +- 0.026 (stat) +-
0.009 (syst) ps-1 and the mean B0_s lifetime, \tau_s = 1.528 +- 0.019 (stat) +-
0.009 (syst) ps, which are consistent and competitive with determinations by
other experiments.Comment: 8 pages, 2 figures, Phys. Rev. Lett 109, 171802 (2012
Azimuthal anisotropy of charged particles at high transverse momenta in PbPb collisions at sqrt(s[NN]) = 2.76 TeV
- Author
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- Abbiendi G
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- Wrochna G
- Wu W
- Wuerthwein F
- Wulz C-E
- Wyslouch B
- Xiao H
- Xie S
- Xu M
- Yagil A
- Yalvac M
- Yang F
- Yang M
- Yang Y
- Yang ZC
- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
- Ziegler J
- Zielinski M
- Zito G
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
The azimuthal anisotropy of charged particles in PbPb collisions at
nucleon-nucleon center-of-mass energy of 2.76 TeV is measured with the CMS
detector at the LHC over an extended transverse momentum (pt) range up to
approximately 60 GeV. The data cover both the low-pt region associated with
hydrodynamic flow phenomena and the high-pt region where the anisotropies may
reflect the path-length dependence of parton energy loss in the created medium.
The anisotropy parameter (v2) of the particles is extracted by correlating
charged tracks with respect to the event-plane reconstructed by using the
energy deposited in forward-angle calorimeters. For the six bins of collision
centrality studied, spanning the range of 0-60% most-central events, the
observed v2 values are found to first increase with pt, reaching a maximum
around pt = 3 GeV, and then to gradually decrease to almost zero, with the
decline persisting up to at least pt = 40 GeV over the full centrality range
measured.Comment: Replaced with published version. Added journal reference and DO
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
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- Adiguzel A
- Adler V
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- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
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- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
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- Aliev T
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- Amsler C
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- Andreev Y
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- Antunes JR
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- Apollinari G
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- Ciesielski R
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- Cimmino A
- Cipriano PMR
- Cirino G
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- Wissing C
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- Won S
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- Wood JS
- Worm SD
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- Wyslouch B
- Xiao H
- Xie S
- Xu M
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- Yang F
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- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
- Ziegler J
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- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Search for new physics with same-sign isolated dilepton events with jets and missing transverse energy
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abdulsalam A
- Acosta D
- Acosta JG
- Adair A
- Adam N
- Adam W
- Adams JR
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
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- Yildirim E
- Yilmaz Y
- Yohay R
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- Yoo J
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- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
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- Zatserklyaniy A
- Zeinali M
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- Zeyrek M
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- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
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- Zhukov V
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- Zielinski M
- Zito G
- Zou W
- Zucchetta A
- Zumerle G
- Zuranski A
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
A search for new physics is performed in events with two same-sign isolated
leptons, hadronic jets, and missing transverse energy in the final state. The
analysis is based on a data sample corresponding to an integrated luminosity of
4.98 inverse femtobarns produced in pp collisions at a center-of-mass energy of
7 TeV collected by the CMS experiment at the LHC. This constitutes a factor of
140 increase in integrated luminosity over previously published results. The
observed yields agree with the standard model predictions and thus no evidence
for new physics is found. The observations are used to set upper limits on
possible new physics contributions and to constrain supersymmetric models. To
facilitate the interpretation of the data in a broader range of new physics
scenarios, information on the event selection, detector response, and
efficiencies is provided.Comment: Published in Physical Review Letter
X-ray emission from the Sombrero galaxy: discrete sources
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahmed I
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alexander J
- Aliev T
- Allfrey P
- Almeida N
- Alver B
- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Anderson M
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Antonelli L
- Antunes JR
- Antunovic Z
- Apanasevich L
- Apollinari G
- Appelt E
- Aranyi A
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- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
- Arisaka K
- Arneodo M
- Asaadi J
- Asghar MI
- Askew A
- Ata M
- Atac M
- Atramentov O
- Attikis A
- Auffray E
- Autermann C
- Auzinger G
- Avery P
- Avetisyan A
- Awad A
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzolini V
- Azzurri P
- Baarmand MM
- Babb J
- Bacchetta N
- Bachtis M
- Baden A
- Baesso P
- Baffioni S
- Bagliesi G
- Bai Y
- Baillon P
- Bainbridge R
- Bakhshiansohi H
- Bakirci MN
- Bakken JA
- Balazs M
- Ball AH
- Ball G
- Ballin J
- Ban Y
- Bandurin D
- Banerjee S
- Banerjee S
- Bansal S
- Banzuzi K
- Barbagli G
- Barberis E
- Barbone L
- Barge D
- Baringer P
- Barker A
- Barnes VE
- Barnett BA
- Barney D
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- Barrett M
- Bartalini P
- Barth C
- Basegmez S
- Basso L
- Battilana C
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- Bauer G
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- Bauerdick LAT
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- Bazterra VE
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- Beauceron S
- Beaudette F
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- Bedjidian M
- Bedoya CF
- Behrenhoff W
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- Bellinger JN
- Belotelov I
- Belyaev A
- Benaglia A
- Bencze G
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- Beuselinck R
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- Bhatti A
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- Bilinskas MJ
- Bilki B
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- Biselli A
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- Bitioukov S
- Blekman F
- Bloch D
- Bloch I
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- Bornheim A
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- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2010
- Field of study
We present a study of discrete X-ray sources in and around the
bulge-dominated, massive Sa galaxy, Sombrero (M104), based on new and archival
Chandra observations with a total exposure of ~200 ks. With a detection limit
of L_X = 1E37 erg/s and a field of view covering a galactocentric radius of ~30
kpc (11.5 arcminute), 383 sources are detected. Cross-correlation with Spitler
et al.'s catalogue of Sombrero globular clusters (GCs) identified from HST/ACS
observations reveals 41 X-rays sources in GCs, presumably low-mass X-ray
binaries (LMXBs). We quantify the differential luminosity functions (LFs) for
both the detected GC and field LMXBs, whose power-low indices (~1.1 for the
GC-LF and ~1.6 for field-LF) are consistent with previous studies for
elliptical galaxies. With precise sky positions of the GCs without a detected
X-ray source, we further quantify, through a fluctuation analysis, the GC LF at
fainter luminosities down to 1E35 erg/s. The derived index rules out a
faint-end slope flatter than 1.1 at a 2 sigma significance, contrary to recent
findings in several elliptical galaxies and the bulge of M31. On the other
hand, the 2-6 keV unresolved emission places a tight constraint on the field
LF, implying a flattened index of ~1.0 below 1E37 erg/s. We also detect 101
sources in the halo of Sombrero. The presence of these sources cannot be
interpreted as galactic LMXBs whose spatial distribution empirically follows
the starlight. Their number is also higher than the expected number of cosmic
AGNs (52+/-11 [1 sigma]) whose surface density is constrained by deep X-ray
surveys. We suggest that either the cosmic X-ray background is unusually high
in the direction of Sombrero, or a distinct population of X-ray sources is
present in the halo of Sombrero.Comment: 11 figures, 5 tables, ApJ in pres
Compressed representation of a partially defined integer function over multiple arguments
- Author
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- Abbiendi G
- Abbrescia M
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- CMS Collaboration
- Coarasa Perez JA
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- Colafranceschi S
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- Cutajar M
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- Czellar S
- D'Agnolo RT
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- Publication venue
- Publication date
- 01/01/2013
- Field of study
In OLAP (OnLine Analitical Processing) data are analysed in an n-dimensional cube. The cube may be represented as a partially defined function over n arguments. Considering that often the function is not defined everywhere, we ask: is there a known way of representing the function or the points in which it is defined, in a more compact manner than the trivial one
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