PENGARUH BAURAN PEMASARAN BANK TERHADAP LOYALITAS NASABAH (BTN SYARIAH KC SURABAYA)

Abstrak Tujuan penelitian ini adalah untuk mengetahui bagaimana pengaruh variabel bauran pemasaran bank terhadap loyalitas nasabah pada BTN Syariah Kc Surabaya. Penelitian ini adalah penelitian kuantitatif. Metode pengumpulan datanya menggunakan kuisioner yang disebar pada responden. Jumlah sampel (responden) dalam penelitian ini yakni 100 nasabah dipilih dengan teknik purposive sampling. Analisis data menggunakan model statistik regresi sederhana. Data diolah menggunakan uji reliabilitas, uji validitas, uji asumsi klasik dan uji statistik. Dari hasil pengolahan data tersebut menunjukkan bahwa Bauran Pemasaran Bank berpengaruh positif dan signifikan terhadap loyalitas nasabah dengan nilai pengaruh sebesar 13,6% dan terbukti t hitung (3,395) lebih besar dari (>) t tabel (1,987), sehingga dapat disimpulkan bahwa semakin tinggi Bauran Pemasaran Bank maka semakin tingi pula loyalitas nasabah BTN Syariah Kc Surabaya. Kata kunci: Bauran pemasaran, Loyalitas nasabah, Perbankan syariah. Abstract The purpose of this study is to know how the influence of marketing mix variables of the bank on customer loyalty at BTN Syariah Kc Surabaya. This research is quantitative research. Methods of data collection used questionnaires distributed to respondents. The number of samples (respondents) in this research that is 100 customers selected by purposive sampling technique. Data analysis used a simple regression statistic model. The data were processed using the test of reliability, validity test, classical assumption test and statistical test. From result of data processing show that Marketing Mix of Bank have positive and significant influence to customer loyalty with influence value 13,6% and proven t count (3,395) bigger than (>) t table (1,987), so it can be concluded that the higher Marketing Mix of the Bank, the higher the loyalty of customers at BTN Syariah Kc Surabaya. Keyword: Marketing mix, Customer loyalty, Syariah finance

Morehead State University Student Members of the American Chemical Society

https://scholarworks.moreheadstate.edu/student_scholarship_posters/1217/thumbnail.jp

Prevalence of Helicobacter pylori infections in patients visiting to gestroenterology department Rehman Medical Institute Khyber Pakhtunkhwa

Gastritis and peptic ulcer is common worldwide as well in Pakistan. H. pylori is causative agent and can survive in acidic medium like stomach. H. pylori is unique bacteria that capable to cause stomach cancer. The objective of present study was to report the prevalence of Helicobacter pylori infections in patients visiting to Rehman Medical Institute Peshawar. In the present descriptive cross-sectional study, a total number of 150 patients visiting to Gastroenterology Department Rehman Medical Institute Peshawar were gone through H. pylori screening test by Immunochromatography (BD ICT) method and test was performed to find out prevalence of Helicobacter pylori infection in patients visiting to Gastroenterology Department Rehman Medical Institute Peshawar. Data was recorded and analysed by SPSS-22 and shown here in the form of tables. Total number of patients was 150, out of them 44 (29.3%) patients were H. pylori positive and 106(70.7%) were H. pylori negative. The prevalence of H. pylori infection is higher in the patients visiting to gastroenterology department of Rehman Medical Institute Peshawar. It is more common in males as compared to female patients. We conclude here that patients of gastroenterology should be screened for H. pylori to cope with treatment & prevention from further complications

Spinal Cord Injury: Causes, types of manifestation and related complications of the patients in northern division of Bangladesh

Background: This study explores Spinal Cord Injuries (SCI) in the Northern Division of Bangladesh, including its etiology, symptoms, and complications. The research focuses on this region to understand the etiology, varieties of SCI presentations, and the issues affected persons encounter. Purpose: to study the causes, symptoms, and complications of Spinal Cord Injuries (SCI) in Northern Bangladesh. Methods: In order to better understand Spinal Cord Injuries (SCI) among patients at Rajshahi Medical College Hospital and Rajshahi-CRP, Northern Division of Bangladesh, a quantitative cross-sectional descriptive design was used in this study. This convenience sample (n=300) includes patients who are undergoing treatment as well as those who have been discharged. Patients with SCI who have not had a head injury meet the inclusion criteria; patients who are unconscious or lack a diagnosis are not. Validated by a clinical physiotherapist, the data collection process uses semi-structured questionnaires and in-person interviews in accordance with ethical criteria that have been authorized by the ethical review board of Rajshahi Medical College. This ensures that patient care is not compromised. Results: The study had 300 participants, 80% male and 20% female, aged 20–50. About 42% were employed, mostly secondary school graduates, and rural residents. Trauma caused 64% of spinal cord injuries and paraplegia. 34% had pressure sores, while 92% had moderate discomfort. Urological and muscle problems affected 70% of patients. 68% of participants had psychological issues, including depression. Autonomic dysreflexia was 14%. Conclusion:  This study illuminates the origins, symptoms, and complications of Spinal Cord Injuries (SCI) in Northern Bangladesh, providing useful insights for better management and care

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Systematic, comprehensive, evidence-based approach to identify neuroprotective interventions for motor neuron disease: using systematic reviews to inform expert consensus

Objectives: Motor neuron disease (MND) is an incurable progressive neurodegenerative disease with limited treatment options. There is a pressing need for innovation in identifying therapies to take to clinical trial. Here, we detail a systematic and structured evidence-based approach to inform consensus decision making to select the first two drugs for evaluation in Motor Neuron Disease-Systematic Multi-arm Adaptive Randomised Trial (MND-SMART: NCT04302870), an adaptive platform trial. We aim to identify and prioritise candidate drugs which have the best available evidence for efficacy, acceptable safety profiles and are feasible for evaluation within the trial protocol. Methods: We conducted a two-stage systematic review to identify potential neuroprotective interventions. First, we reviewed clinical studies in MND, Alzheimer’s disease, Huntington’s disease, Parkinson’s disease and multiple sclerosis, identifying drugs described in at least one MND publication or publications in two or more other diseases. We scored and ranked drugs using a metric evaluating safety, efficacy, study size and study quality. In stage two, we reviewed efficacy of drugs in MND animal models, multicellular eukaryotic models and human induced pluripotent stem cell (iPSC) studies. An expert panel reviewed candidate drugs over two shortlisting rounds and a final selection round, considering the systematic review findings, late breaking evidence, mechanistic plausibility, safety, tolerability and feasibility of evaluation in MND-SMART. Results: From the clinical review, we identified 595 interventions. 66 drugs met our drug/disease logic. Of these, 22 drugs with supportive clinical and preclinical evidence were shortlisted at round 1. Seven drugs proceeded to round 2. The panel reached a consensus to evaluate memantine and trazodone as the first two arms of MND-SMART. Discussion: For future drug selection, we will incorporate automation tools, text-mining and machine learning techniques to the systematic reviews and consider data generated from other domains, including high-throughput phenotypic screening of human iPSCs

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018 population-based measurement studies with 88.6 million participants

© The Author(s) 2018. Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood pressure. Methods: We pooled 1018 population-based studies with blood pressure measurements on 88.6 million participants from 1985 to 2016. We first calculated mean systolic blood pressure (SBP), mean diastolic blood pressure (DBP) and prevalence of raised blood pressure by sex and 10-year age group from 20-29 years to 70-79 years in each study, taking into account complex survey design and survey sample weights, where relevant. We used a linear mixed effect model to quantify the association between (probittransformed) prevalence of raised blood pressure and age-group- and sex-specific mean blood pressure. We calculated the contributions of change in mean SBP and DBP, and of change in the prevalence-mean association, to the change in prevalence of raised blood pressure. Results: In 2005-16, at the same level of population mean SBP and DBP, men and women in South Asia and in Central Asia, the Middle East and North Africa would have the highest prevalence of raised blood pressure, and men and women in the highincome Asia Pacific and high-income Western regions would have the lowest. In most region-sex-age groups where the prevalence of raised blood pressure declined, one half or more of the decline was due to the decline in mean blood pressure. Where prevalence of raised blood pressure has increased, the change was entirely driven by increasing mean blood pressure, offset partly by the change in the prevalence-mean association. Conclusions: Change in mean blood pressure is the main driver of the worldwide change in the prevalence of raised blood pressure, but change in the high-blood-pressure tail of the distribution has also contributed to the change in prevalence, especially in older age groups

Repositioning of the global epicentre of non-optimal cholesterol

High blood cholesterol is typically considered a feature of wealthy western countries(1,2). However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world(3) and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health(4,5). However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol-which is a marker of cardiovascular riskchanged from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million-4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world.Peer reviewe