Microbial Nitrate Dependent Fe²⁺ Oxidation: A Potential Early Mars Metabolism

This thesis experimentally investigates the proposition that aqueous environments with anoxic, reducing, circumneutral conditions, inorganic electron donors and oxidants such as nitrate may have allowed chemolithotrophic microbial metabolisms, such as nitrate-dependent Fe2+ oxidation (NDFO), to thrive on early Mars. The NDFO microorganisms, Acidovorax sp. strain BoFeN1, Paracoccus sp. strain KS1 and Pseudogulbenkiania sp. strain 2002, are demonstrated to grow lithoautotrophically with a Mars-relevant olivine Fe2+ source and in martian simulant media developed from in situ and meteorite geochemical data. Additionally, mixotrophic NDFO with Fe2+ and an organic co-substrate as electron donors, was shown to increase the extent of microbial growth, which gains importance in light of the confirmation of complex organics at the martian surface. Biomineralised microbial features were discovered after culture with olivine and the oxidation of Fe2+ was measured in heterotrophic cultures. Microfossils and Fe3+ compounds in reducing contexts provide targets for biosignature detection missions. In addition, this work presents findings on the biochemical mechanisms of NDFO, quantifying the relative contributions of the Nar respiratory nitrate reductase enzyme, putative ferroxidases and nitrite accumulation to Fe2+ oxidation during nitrate reduction. Gene knockout experiments revealed that Fe2+ oxidation in the heterotrophic Salmonella enterica Serovar Typhimurium strain SL1344 is largely driven by the production of reactive nitrite ions during Nar activity. Draft genome analysis of Acidovorax sp. strain BoFeN1 and Paracoccus sp. strain KS1 revealed potential mechanisms of electron acquisition during Fe2+ oxidation, underlining that multiple mechanisms of NDFO exist. The combined findings of this thesis support the plausibility of NDFO in the deep martian past and propose mechanisms by which evidence may be preserved in the geological record of that planet

Parasite-stress promotes in-group assortative sociality: the cases of strong family ties and heightened religiosity

Throughout the world people differ in the magnitude with which they value strong family ties or heightened religiosity. We propose that this cross-cultural variation is a result of a contingent psychological adaptation that facilitates in-group assortative sociality in the face of high levels of parasite-stress while devaluing in-group assortative sociality in areas with low levels of parasite-stress. This is because in-group assortative sociality is more important for the avoidance of infection from novel parasites and for the management of infection in regions with high levels of parasite-stress compared with regions of low infectious disease stress. We examined this hypothesis by testing the predictions that there would be a positive association between parasite-stress and strength of family ties or religiosity. We conducted this study by comparing among nations and among states in the United States of America. We found for both the international and the interstate analyses that in-group assortative sociality was positively associated with parasite-stress. This was true when controlling for potentially confounding factors such as human freedom and economic development. The findings support the parasite-stress theory of sociality, that is, the proposal that parasite-stress is central to the evolution of social life in humans and other animals

Learning From Early Attempts to Generalize Darwinian Principles to Social Evolution

Copyright University of Hertfordshire & author.Evolutionary psychology places the human psyche in the context of evolution, and addresses the Darwinian processes involved, particularly at the level of genetic evolution. A logically separate and potentially complementary argument is to consider the application of Darwinian principles not only to genes but also to social entities and processes. This idea of extending Darwinian principles was suggested by Darwin himself. Attempts to do this appeared as early as the 1870s and proliferated until the early twentieth century. But such ideas remained dormant in the social sciences from the 1920s until after the Second World War. Some lessons can be learned from this earlier period, particularly concerning the problem of specifying the social units of selection or replication

Tau Neutrinos Favored over Sterile Neutrinos in Atmospheric Muon Neutrino Oscillations

The previously published atmospheric neutrino data did not distinguish whether muon neutrinos were oscillating into tau neutrinos or sterile neutrinos, as both hypotheses fit the data. Using data recorded in 1100 live-days of the Super-Kamiokande detector, we use three complementary data samples to study the difference in zenith angle distribution due to neutral currents and matter effects. We find no evidence favoring sterile neutrinos, and reject the hypothesis at the 99% confidence level. On the other hand, we find that oscillation between muon and tau neutrinos suffices to explain all the results in hand.Comment: 9 pages with 2 figures, submitted to PR

Genetic indicators of iron limitation in wild populations of \u3cem\u3eThalassiosira oceanica\u3c/em\u3e from the northeast Pacific Ocean

Assessing the iron (Fe) nutritional status of natural diatom populations has proven challenging as physiological and molecular responses can differ in diatoms of the same genus. We evaluated expression of genes encoding flavodoxin (FLDA1) and an Fe-starvation induced protein (ISIP3) as indicators of Fe limitation in the marine diatom Thalassiosira oceanica. The specificity of the response to Fe limitation was tested in cultures grown under Fe- and macronutrient-deficient conditions, as well as throughout the diurnal light cycle. Both genes showed a robust and specific response to Fe limitation in laboratory cultures and were detected in small volume samples collected from the northeast Pacific, demonstrating the sensitivity of this method. Overall, FLDA1 and ISIP3 expression was inversely related to Fe concentrations and offered insight into the Fe nutritional health of T. oceanica in the field. As T. oceanica is a species tolerant to low Fe, indications of Fe limitation in T. oceanica populations may serve as a proxy for severe Fe stress in the overall diatom community. At two shallow coastal locations, FLD1A and ISIP3 expression revealed Fe stress in areas where dissolved Fe concentrations were high, demonstrating that this approach may be powerful for identifying regions where Fe supply may not be biologically available

Stellar, brown dwarf and multiple star properties from a radiation hydrodynamical simulation of star cluster formation

We report the statistical properties of stars, brown dwarfs and multiple systems obtained from the largest radiation hydrodynamical simulation of star cluster formation to date that resolves masses down to the opacity limit for fragmentation (a few Jupiter masses). The initial conditions are identical to those of previous barotropic calculations published by Bate, but this time the calculation is performed using a realistic equation of state and radiation hydrodynamics. The calculation uses sink particles to model 183 stars and brown dwarfs, including 28 binaries and 12 higher-order multiple systems, the properties of which are compared the results from observational surveys. We find that the radiation hydrodynamical/sink particle simulation reproduces many observed stellar properties very well. In particular, whereas using a barotropic equation of state produces more brown dwarfs than stars, the inclusion of radiative feedback results in a stellar mass function and a ratio of brown dwarfs to stars in good agreement with observations of Galactic star-forming regions. In addition, many of the other statistical properties of the stars and brown dwarfs are in reasonable agreement with observations, including multiplicity as a function of primary mass, the frequency of very-low-mass binaries, and general trends for the mass ratio and separation distributions of binaries. We also examine the velocity dispersion of the stars, the distributions of disc truncation radii due to dynamical interactions, and coplanarity of orbits and sink particle spins in multiple systems. Overall, the calculation produces a cluster of stars whose statistical properties are difficult to distinguish from observed systems, implying that gravity, hydrodynamics, and radiative feedback are the primary ingredients for determining the origin of the statistical properties of low-mass stars.Comment: Accepted for publication in MNRAS, 33 pages, 23 figures. Animations can be found at http://www.astro.ex.ac.uk/people/mbate

The twilight of the Liberal Social Contract? On the Reception of Rawlsian Political Liberalism

This chapter discusses the Rawlsian project of public reason, or public justification-based 'political' liberalism, and its reception. After a brief philosophical rather than philological reconstruction of the project, the chapter revolves around a distinction between idealist and realist responses to it. Focusing on political liberalism’s critical reception illuminates an overarching question: was Rawls’s revival of a contractualist approach to liberal legitimacy a fruitful move for liberalism and/or the social contract tradition? The last section contains a largely negative answer to that question. Nonetheless the chapter's conclusion shows that the research programme of political liberalism provided and continues to provide illuminating insights into the limitations of liberal contractualism, especially under conditions of persistent and radical diversity. The programme is, however, less receptive to challenges to do with the relative decline of the power of modern states

Constitutivism

A brief explanation and overview of constitutivism

Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV

The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration