746 research outputs found
Turkey-EU Statement on Refugees 2016: Analysis from the Point of View of Liberalism
The European Union drastic ally changed its welcoming refugee policy of 2015 in the following year by giving a statement with Turkey, limiting the number refugees allowed to comeintot he EU. Liberalism can explain this abrupt regime change. National interest groups and the aggregation of their preferences to national interests are analyzed. Then, international negotiations of these aggregated preferences are studied to explain the existence or absence of cooperation. Non-cooperation in the first phase explains the partially welcoming policy of 2015, while forced cooperation in 2016 explains the statement with Turkey.Европейский союз кардинально изменил свою гостеприимную политику в отношении беженцев в 2016 г. посредством заявления, принятого Европейским сообществом и Турцией. Они установили ограничения по числу беженцев, которых должен принять Европейский союз. Такая резкая смена подхода объясняется либерализмом. Проанализированное автором статьи объединение интересов национальных групп есть совокупность всех предпочтений государств. Также было изучено влияние позиций этих государств на международные переговоры. Это позволило объяснить причины отсутствия и присутствия сотрудничества на разных этапах. На первом этапе объясняется неполная гостеприимная политика, установленная в 2015 г., в отношении беженцев без участия других стран ЕС, в то время как соглашение с Турцией показывает принудительное сотрудничество
Low temperature breakdown of coherent tunneling in amorphous solids induced by the nuclear quadrupole interaction
We consider the effect of the internal nuclear quadrupole interaction on
quantum tunneling in complex multi-atomic two-level systems. Two distinct
regimes of strong and weak interactions are found. The regimes depend on the
relationship between a characteristic energy of the nuclear quadrupole
interaction and a bare tunneling coupling strength
. When , the internal interaction is
negligible and tunneling remains coherent determined by . When
, coherent tunneling breaks down and an effective
tunneling amplitude decreases by an exponentially small overlap factor
between internal ground states of left and right wells of a
tunneling system. This affects thermal and kinetic properties of tunneling
systems at low temperatures . The theory is applied for
interpreting the anomalous behavior of the resonant dielectric susceptibility
in amorphous solids at low temperatures mK where the nuclear
quadrupole interaction breaks down coherent tunneling. We suggest the
experiments with external magnetic fields to test our predictions and to
clarify the internal structure of tunneling systems in amorphous solids.Comment: To appear in the Physical Review
The effect of the spin-orbit interaction on the band gap of half-metals
The spin-orbit interaction can cause a nonvanishing density of states (DOS)
within the minority-spin band gap of half-metals around the Fermi level. We
examine the magnitude of the effect in Heusler alloys, zinc-blende half metals
and diluted magnetic semiconductors, using first-principles calculations. We
find that the ratio of spin-down to spin-up DOS at the Fermi level can range
from below 1% (e.g. 0.5% for NiMnSb) over several percents (4.2% for (Ga,Mn)As)
to 13% for MnBi.Comment: 5 pages, 3 figure
A Review of Target Mass Corrections
With recent advances in the precision of inclusive lepton--nuclear scattering
experiments, it has become apparent that comparable improvements are needed in
the accuracy of the theoretical analysis tools. In particular, when extracting
parton distribution functions in the large-x region, it is crucial to correct
the data for effects associated with the nonzero mass of the target. We present
here a comprehensive review of these target mass corrections (TMC) to structure
functions data, summarizing the relevant formulas for TMCs in electromagnetic
and weak processes. We include a full analysis of both hadronic and partonic
masses, and trace how these effects appear in the operator product expansion
and the factorized parton model formalism, as well as their limitations when
applied to data in the x->1 limit. We evaluate the numerical effects of TMCs on
various structure functions, and compare fits to data with and without these
corrections.Comment: 41 pages, 13 figures; minor updates to match published versio
Half-Metallic Ferrimagnetism in Mn_2VAl
We show that Mn_2VAl is a compound for which the generalized gradient
approximation (GGA) to the exchange-correlation functional in density
functional theory makes a qualitative change in predicted behavior compared to
the usual local density approximation (LDA). Application of GGA leads to
prediction of Mn_2VAl being a half-metallic ferrimagnet, with the minority
channel being the conducting one. The electronic and magnetic structure is
analyzed and contrasted with the isostructural enhanced semimetal Fe_2VAl.Comment: 5 pages, Latex, 6 postscript figures. Description and figures of the
(minority) Fermi surfaces have been adde
Global Regulation of Nucleotide Biosynthetic Genes by c-Myc
The c-Myc transcription factor is a master regulator and integrates cell proliferation, cell growth and metabolism through activating thousands of target genes. Our identification of direct c-Myc target genes by chromatin immunoprecipitation (ChIP) coupled with pair-end ditag sequencing analysis (ChIP-PET) revealed that nucleotide metabolic genes are enriched among c-Myc targets, but the role of Myc in regulating nucleotide metabolic genes has not been comprehensively delineated.Here, we report that the majority of genes in human purine and pyrimidine biosynthesis pathway were induced and directly bound by c-Myc in the P493-6 human Burkitt's lymphoma model cell line. The majority of these genes were also responsive to the ligand-activated Myc-estrogen receptor fusion protein, Myc-ER, in a Myc null rat fibroblast cell line, HO.15 MYC-ER. Furthermore, these targets are also responsive to Myc activation in transgenic mouse livers in vivo. To determine the functional significance of c-Myc regulation of nucleotide metabolism, we sought to determine the effect of loss of function of direct Myc targets inosine monophosphate dehydrogenases (IMPDH1 and IMPDH2) on c-Myc-induced cell growth and proliferation. In this regard, we used a specific IMPDH inhibitor mycophenolic acid (MPA) and found that MPA dramatically inhibits c-Myc-induced P493-6 cell proliferation through S-phase arrest and apoptosis.Taken together, these results demonstrate the direct induction of nucleotide metabolic genes by c-Myc in multiple systems. Our finding of an S-phase arrest in cells with diminished IMPDH activity suggests that nucleotide pool balance is essential for c-Myc's orchestration of DNA replication, such that uncoupling of these two processes create DNA replication stress and apoptosis
The crossover from propagating to strongly scattered acoustic modes of glasses observed in densified silica
Spectroscopic results on low frequency excitations of densified silica are
presented and related to characteristic thermal properties of glasses. The end
of the longitudinal acoustic branch is marked by a rapid increase of the
Brillouin linewidth with the scattering vector. This rapid growth saturates at
a crossover frequency Omega_co which nearly coincides with the center of the
boson peak. The latter is clearly due to additional optic-like excitations
related to nearly rigid SiO_4 librations as indicated by hyper-Raman
scattering. Whether the onset of strong scattering is best described by
hybridization of acoustic modes with these librations, by their elastic
scattering (Rayleigh scattering) on the local excitations, or by soft
potentials remains to be settled.Comment: 14 pages, 6 figures, to be published in a special issue of J. Phys.
Condens. Matte
Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.
Emmanuelle Souzeau, who contributed to analysis of data, was inadvertently omitted from the author list in the originally published version of this Article. This has now been corrected in both the PDF and HTML versions of the Article
Shrinking a large dataset to identify variables associated with increased risk of Plasmodium falciparum infection in Western Kenya
Large datasets are often not amenable to analysis using traditional single-step approaches. Here, our general objective was to apply imputation techniques, principal component analysis (PCA), elastic net and generalized linear models to a large dataset in a systematic approach to extract the most meaningful predictors for a health outcome. We extracted predictors for Plasmodium falciparum infection, from a large covariate dataset while facing limited numbers of observations, using data from the People, Animals, and their Zoonoses (PAZ) project to demonstrate these techniques: data collected from 415 homesteads in western Kenya, contained over 1500 variables that describe the health, environment, and social factors of the humans, livestock, and the homesteads in which they reside. The wide, sparse dataset was simplified to 42 predictors of P. falciparum malaria infection and wealth rankings were produced for all homesteads. The 42 predictors make biological sense and are supported by previous studies. This systematic data-mining approach we used would make many large datasets more manageable and informative for decision-making processes and health policy prioritization
Study of CP violation in Dalitz-plot analyses of B0 --> K+K-KS, B+ --> K+K-K+, and B+ --> KSKSK+
We perform amplitude analyses of the decays , , and , and measure CP-violating
parameters and partial branching fractions. The results are based on a data
sample of approximately decays, collected with the
BABAR detector at the PEP-II asymmetric-energy factory at the SLAC National
Accelerator Laboratory. For , we find a direct CP asymmetry
in of , which differs
from zero by . For , we measure the
CP-violating phase .
For , we measure an overall direct CP asymmetry of
. We also perform an angular-moment analysis of
the three channels, and determine that the state can be described
well by the sum of the resonances , , and
.Comment: 35 pages, 68 postscript figures. v3 - minor modifications to agree
with published versio
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