2,797 research outputs found

    Ranking Economics Journals, Economics Departments, and Economists Using Teaching-Focused Research Productivity

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    This paper constructs new rankings of economics journals, economics departments, and economists that employ a measure of teaching-focused research productivity, an area of growing importance in recent years. The ranking methodologies presented here use information from articles that were published from 1991 through the early part of 2005 within the Journal of Economic Literature\u27 s economic education classifications (A200-A290). The Journal of Economic Literature tops the list of journals, followed by the Review of Economics and Statistics and the American Economic Review . Among the top institutions are Vanderbilt University, Indiana University, and the University of Wisconsin. Others that rank high here, such as Oberlin College and Denison University, do not often fare as well using methodologies that evaluate more traditional types of economics research. Finally, among the economists we find that John Siegfried, William Becker, and Michael Watts are ranked above other economists

    Multivariate analysis of heavy metal concentrations in the different tissues of four intertidal clams from Peninsular Malaysia

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    Four species of clams (Macoma sp., Siliqua sp., Pharus sp. and Mactra sp.) were collected from the intertidal area of Peninsular Malaysia, Their different soft tissues (siphon, muscle, foot, mantle, gill and remaining soft tissues), and shells were analyzed for the concentrations of Cd, Cu, Fe, Ni, Pb and Zn. The relationships of heavy metals in the different tissues of clams were detennined using multivariate analyses including correlation analysis, cluster analysis and multiple linear stepwise regression analysis (MLSRA). Metal distribution in the clams were explained using correlation analysis, which indicated that the shell was not signihcantly (P> 0.05) correlated with other tissues and the shell is also clustered differently from the rest of soft tissues as indicated by the cluster analysis. Among the soft tissues, it was found that the gills and mantle of all clams were identified as the most influential tissues in the accumulation of heavy metals in the total soft tissues for the clams by MLSRA, The present study found that the distributions of heavy metals in the different tissues of clams were related to their differences in biological and ecological aspects. Since the multivariate analyses used in this study can reduce the cost and time involved in identifying an effective tissue to monitor the heavy metal(s) bioavailability and contamination (Yap et al. 2010), this preliminary finding provided an altemative for future environmental management in the intertidal area of Peninsular Malaysia

    Group-based trajectory models: assessing adherence to antihypertensive medication in older adults in a community pharmacy setting.

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    Antihypertensive medication nonadherence is highly prevalent, leading to uncontrolled blood pressure. Methods that facilitate the targeting and tailoring of adherence interventions in clinical settings are required. Group-Based Trajectory Modeling (GBTM) is a newer method to evaluate adherence using pharmacy dispensing (refill) data that has advantages over traditional refill adherence metrics (e.g. Proportion of Days Covered) by identifying groups of patients who may benefit from adherence interventions, and identifying patterns of adherence behavior over time that may facilitate tailoring of an adherence intervention. We evaluated adherence to antihypertensive medication in 905 patients over a 12-month period in a community pharmacy setting using GBTM, identifying three subgroups of adherence patterns: 52.8%, 40.7%, and 6.5% had very high, high, and low adherence, respectively. However, GBTM failed to demonstrate predictive validity with blood pressure at 12 months. Further research on the validity of adherence measures that facilitate interventions in clinical settings is required

    Exercise and Physical Activity for the Post–Aortic Dissection Patient: The Clinician's Conundrum

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    Despite the paucity of evidence, it is often presumed, and is physiologically plausible, that sudden, acute elevations in blood pressure may transiently increase the risk of recurrent aortic dissection (AD) or rupture in patients with a prior AD, because a post‐dissection aorta is almost invariably dilated and may thus experience greater associated wall stress as compared with a nondilated aorta. Few data are available regarding the specific types and intensities of exercise that may be both safe and beneficial for this escalating patient population. The purpose of this editorial/commentary is to further explore this conundrum for clinicians caring for and counseling AD survivors. Moderate‐intensity cardiovascular activity may be cardioprotective in this patient cohort. It is likely that severe physical activity restrictions may reduce functional capacity and quality of life in post‐AD patients and thus be harmful, underscoring the importance of further exploring the role of physical activity and/or structured exercise in this at‐risk patient population.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/116077/1/clc22481_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/116077/2/clc22481.pd

    Ultraviolet radiation shapes seaweed communities

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    Using Bayesian Aldrich-McKelvey Scaling to Study Citizens' Ideological Preferences and Perceptions

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    Aldrich‐McKelvey scaling is a powerful method that corrects for differential‐item functioning (DIF) in estimating the positions of political stimuli (e.g., parties and candidates) and survey respondents along a latent policy dimension from issue scale data. DIF arises when respondents interpret issue scales (e.g., the standard liberal‐conservative scale) differently and distort their placements of the stimuli and themselves. We develop a Bayesian implementation of the classical maximum likelihood Aldrich‐McKelvey scaling method that overcomes some important shortcomings in the classical procedure. We then apply this method to study citizens' ideological preferences and perceptions using data from the 2004–2012 American National Election Studies and the 2010 Cooperative Congressional Election Study. Our findings indicate that DIF biases self‐placements on the liberal‐conservative scale in a way that understates the extent of polarization in the contemporary American electorate and that citizens have remarkably accurate perceptions of the ideological positions of senators and Senate candidates

    Palmitoylethanolamide exerts neuroprotective effects in mixed neuroglial cultures and organotypic hippocampal slices via peroxisome proliferator-activated receptor-α

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    <p>Abstract</p> <p>Background</p> <p>In addition to cytotoxic mechanisms directly impacting neurons, β-amyloid (Aβ)-induced glial activation also promotes release of proinflammatory molecules that may self-perpetuate reactive gliosis and damage neighbouring neurons, thus amplifying neuropathological lesions occurring in Alzheimer's disease (AD). Palmitoylethanolamide (PEA) has been studied extensively for its anti-inflammatory, analgesic, antiepileptic and neuroprotective effects. PEA is a lipid messenger isolated from mammalian and vegetable tissues that mimics several endocannabinoid-driven actions, even though it does not bind to cannabinoid receptors. Some of its pharmacological properties are considered to be dependent on the expression of peroxisome proliferator-activated receptors-α (PPARα).</p> <p>Findings</p> <p>In the present study, we evaluated the effect of PEA on astrocyte activation and neuronal loss in models of Aβ neurotoxicity. To this purpose, primary rat mixed neuroglial co-cultures and organotypic hippocampal slices were challenged with Aβ<sub>1-42 </sub>and treated with PEA in the presence or absence of MK886 or GW9662, which are selective PPARα and PPARγ antagonists, respectively. The results indicate that PEA is able to blunt Aβ-induced astrocyte activation and, subsequently, to improve neuronal survival through selective PPARα activation. The data from organotypic cultures confirm that PEA anti-inflammatory properties implicate PPARα mediation and reveal that the reduction of reactive gliosis subsequently induces a marked rebound neuroprotective effect on neurons.</p> <p>Conclusions</p> <p>In line with our previous observations, the results of this study show that PEA treatment results in decreased numbers of infiltrating astrocytes during Aβ challenge, resulting in significant neuroprotection. PEA could thus represent a promising pharmacological tool because it is able to reduce Aβ-evoked neuroinflammation and attenuate its neurodegenerative consequences.</p

    Measurement of the Bottom-Strange Meson Mixing Phase in the Full CDF Data Set

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    We report a measurement of the bottom-strange meson mixing phase \beta_s using the time evolution of B0_s -> J/\psi (->\mu+\mu-) \phi (-> K+ K-) decays in which the quark-flavor content of the bottom-strange meson is identified at production. This measurement uses the full data set of proton-antiproton collisions at sqrt(s)= 1.96 TeV collected by the Collider Detector experiment at the Fermilab Tevatron, corresponding to 9.6 fb-1 of integrated luminosity. We report confidence regions in the two-dimensional space of \beta_s and the B0_s decay-width difference \Delta\Gamma_s, and measure \beta_s in [-\pi/2, -1.51] U [-0.06, 0.30] U [1.26, \pi/2] at the 68% confidence level, in agreement with the standard model expectation. Assuming the standard model value of \beta_s, we also determine \Delta\Gamma_s = 0.068 +- 0.026 (stat) +- 0.009 (syst) ps-1 and the mean B0_s lifetime, \tau_s = 1.528 +- 0.019 (stat) +- 0.009 (syst) ps, which are consistent and competitive with determinations by other experiments.Comment: 8 pages, 2 figures, Phys. Rev. Lett 109, 171802 (2012

    Measurement of the cross-section and charge asymmetry of WW bosons produced in proton-proton collisions at s=8\sqrt{s}=8 TeV with the ATLAS detector

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    This paper presents measurements of the W+μ+νW^+ \rightarrow \mu^+\nu and WμνW^- \rightarrow \mu^-\nu cross-sections and the associated charge asymmetry as a function of the absolute pseudorapidity of the decay muon. The data were collected in proton--proton collisions at a centre-of-mass energy of 8 TeV with the ATLAS experiment at the LHC and correspond to a total integrated luminosity of 20.2~\mbox{fb^{-1}}. The precision of the cross-section measurements varies between 0.8% to 1.5% as a function of the pseudorapidity, excluding the 1.9% uncertainty on the integrated luminosity. The charge asymmetry is measured with an uncertainty between 0.002 and 0.003. The results are compared with predictions based on next-to-next-to-leading-order calculations with various parton distribution functions and have the sensitivity to discriminate between them.Comment: 38 pages in total, author list starting page 22, 5 figures, 4 tables, submitted to EPJC. All figures including auxiliary figures are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/STDM-2017-13
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