IRAKA: The first Colombian soil information system with digital soil mapping products

Los avances en ciencia y tecnología combinados con la necesidad de manejar y administrar los recursos naturales han resultó en un aumento gradual en la disponibilidad de datos del suelo. Esto ha permitido caracterizar, describir o proponer proyectos para abordar cuestiones como la degradación del suelo, la productividad agrícola, las amenazas y los servicios de los ecosistemas. A pesar de la disponibilidad de datos del suelo, los usuarios buscan cada vez más información adicional, oportuna y confiable. para dar respuesta a situaciones actuales y futuras, como la seguridad alimentaria y el cambio climático. IRAKA es un suelo sistema de información para el altiplano cundiboyacense colombiano y el primero en brindar información adicional de fuentes oficiales disponibles. Tiene un diseño modular basado en la organización de una base de datos de suelos cuya estructura incorporó 299 perfiles, 1432 muestras y 55 propiedades y la integración, armonización, y estandarización de 8 estudios de suelos realizados en la zona. La información estructurada permitió modelar y validando las propiedades físicas y químicas a través del mapeo digital del suelo y comparando diferentes máquinas técnicas de aprendizaje, incluyendo bosque aleatorio, guardabosques, máquina de vectores de apoyo y modelos de conjunto de estos Técnicas Las interpolaciones de 11 propiedades cuantitativas y 1 propiedad cualitativa resultaron en aceptables coeficientes de bondad de ajuste debido a diferentes factores: variabilidad de la propiedad, representatividad, distribución en el área de estudio y descripción de la propiedad basada en covariables ambientales. Toda la información generada ha sido disponible para un uso generalizado en diferentes servicios web geográficos. Así, IRAKA contribuye a la gestión de la información y el conocimiento a través de técnicas y herramientas que permiten a los usuarios visualizar nuevos información, utilizar la información y llamar la atención sobre nuevos estudios y mejorar las bases de datos en las que la confianza el nivel es insuficiente y no permite la toma de decisiones

Improving Latin American soil information database for digital soil mapping enhances its usability and scalability

Spatial soil databases can help model complex phenomena in which soils are decisive, for example, evaluating agricultural potential or estimating carbon storage capacity. The Soil Information System for Latin America and the Caribbean, SISLAC, is a regional initiative promoted by the FAO's South American Soil Partnership to contribute to the sustainable management of soil. SISLAC includes data coming from 49,084 soil profiles distributed unevenly across the continent, making it the region's largest soil database. However, some problems hinder its usages, such as the quality of the data and its high dimensionality. The objective of this research is twofold. First, to evaluate the quality of SISLAC and its data values and generate a new, improved version that meets the minimum quality requirements to be used by different interests or practical applications. Second, to demonstrate the potential of improved soil profile databases to generate more accurate information on soil properties, by conducting a case study to estimate the spatial variability of the percentage of soil organic carbon using 192 profiles in a 1473 km2 region located in the department of Valle del Cauca, Colombia. The findings show that 15 percent of the existing soil profiles had an inaccurate description of the diagnostic horizons. Further correction of an 4.5 additional percent of existing inconsistencies improved overall data quality. The improved database consists of 41,691 profiles and is available for public use at ttps://doi.org/10.5281/zenodo.6540710 (Díaz-Guadarrama, S. & Guevara, M., 2022). The updated profiles were segmented using algorithms for quantitative pedology to estimate the spatial variability. We generated segments one centimeter thick along with each soil profile data, then the values of these segments were adjusted using a spline-type function to enhance vertical continuity and reliability. Vertical variability was estimated up to 150 cm in-depth, while ordinary kriging predicts horizontal variability at three depth intervals, 0 to 5, 5 to 15, and 15 to 30 cm, at 250 m-spatial resolution, following the standards of the GlobalSoilMap project. Finally, the leave-one-out cross validation provides information for evaluating the kriging model performance, obtaining values for the RMSE index between 1.77% and 1.79% and the R2 index greater than 0.5. The results show the usability of SISLAC database to generate spatial information on soil properties and suggest further efforts to collect a more significant amount of data to guide sustainable soil management.Fil: Diaz Guadamarra, Sergio. Universidad Nacional de Colombia. Facultad de Ciencias Agrarias. Departamento de Agronomía; ColombiaFil: Lizarazo, Iván. Universidad Nacional de Colombia. Facultad de Ciencias Agrarias. Departamento de Agronomía; ColombiaFil: Guevara, Mario. Universidad Nacional Autónoma de México. Campus Juriquilla. Centro de Geociencias; MéxicoFil: Guevara, Mario. Universidad Nacional Autónoma de México.Campus Juriquilla. Centro de Geociencias; México. United States Department of Agriculture. Soil Salinity National Laboratory, Estados UnidosFil: Angelini, Marcos Esteban. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Suelos; Argentina. Wageningen University. Soil Geography and Landscape Group; Países Bajos. International Soil Reference and Information Centre. World Soil Information; Países BajosFil: Araujo Carrillo, Gustavo A. Corporación Colombiana de Investigación Agropecuaria AGROSAVIA; ColombiaFil: Argeñal, Jainer. Universidad Nacional Autónoma de Honduras. Facultad de Ciencias; Honduras.Fil: Armas, Daphne. Universidad de Almería. Departamento de Agronomía, Edif. CITEIIB, España.Fil: Balsa, Rafael A. Ministerio de Desarrollo Agrario y Riego. Dirección General de Asuntos Ambientales Agrarios, Perú.Fil: Bolivar, Adriana. Instituto Geográfico Agustín Codazzi. Subdirección Agrología; ColombiaFil: Bustamante, Nelson. Servicio Agrícola y Ganadero; Chile.Fil: Dart, Ricardo O. Embrapa Solos; BrasilFil: Dell Acqua, Martín. Ministerio de Ganadería, Agricultura y Pesca. Dirección General de Recursos Naturales; UruguayFil: Lencina, Arnulfo. Universidad Nacional de Asunción. Facultad de Ciencias Agrarias; ParaguayFil: Figueredo, Hernán. Sociedad Boliviana de la Ciencia del Suelo; Bolivia.Fil: Fontes, Fernando. Ministerio de Ganadería, Agricultura y Pesca. Dirección General de Recursos Naturales; UruguayFil: Gutierrez Diaz, Joan S. Aarhus University. Faculty of Science and Technology,.Department of Agroecology; DinamarcaFil: Jiménez, Wilmer. Ministerio de Agricultura y Ganadería; Ecuador.Fil: Rodriguez, Dario Martin. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Suelos; ArgentinaFil: Schulz, Guillermo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Suelos; ArgentinaFil: Tenti Vuegen, Leonardo Mauricio. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Suelos; Argentin

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

The genetic architecture of the human cerebral cortex

The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder

Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants

Summary Background Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. Methods For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a Bayesian hierarchical model to estimate trends from 1985 to 2019 in mean height and mean BMI in 1-year age groups for ages 5–19 years. The model allowed for non-linear changes over time in mean height and mean BMI and for non-linear changes with age of children and adolescents, including periods of rapid growth during adolescence. Findings We pooled data from 2181 population-based studies, with measurements of height and weight in 65 million participants in 200 countries and territories. In 2019, we estimated a difference of 20 cm or higher in mean height of 19-year-old adolescents between countries with the tallest populations (the Netherlands, Montenegro, Estonia, and Bosnia and Herzegovina for boys; and the Netherlands, Montenegro, Denmark, and Iceland for girls) and those with the shortest populations (Timor-Leste, Laos, Solomon Islands, and Papua New Guinea for boys; and Guatemala, Bangladesh, Nepal, and Timor-Leste for girls). In the same year, the difference between the highest mean BMI (in Pacific island countries, Kuwait, Bahrain, The Bahamas, Chile, the USA, and New Zealand for both boys and girls and in South Africa for girls) and lowest mean BMI (in India, Bangladesh, Timor-Leste, Ethiopia, and Chad for boys and girls; and in Japan and Romania for girls) was approximately 9–10 kg/m2. In some countries, children aged 5 years started with healthier height or BMI than the global median and, in some cases, as healthy as the best performing countries, but they became progressively less healthy compared with their comparators as they grew older by not growing as tall (eg, boys in Austria and Barbados, and girls in Belgium and Puerto Rico) or gaining too much weight for their height (eg, girls and boys in Kuwait, Bahrain, Fiji, Jamaica, and Mexico; and girls in South Africa and New Zealand). In other countries, growing children overtook the height of their comparators (eg, Latvia, Czech Republic, Morocco, and Iran) or curbed their weight gain (eg, Italy, France, and Croatia) in late childhood and adolescence. When changes in both height and BMI were considered, girls in South Korea, Vietnam, Saudi Arabia, Turkey, and some central Asian countries (eg, Armenia and Azerbaijan), and boys in central and western Europe (eg, Portugal, Denmark, Poland, and Montenegro) had the healthiest changes in anthropometric status over the past 3·5 decades because, compared with children and adolescents in other countries, they had a much larger gain in height than they did in BMI. The unhealthiest changes—gaining too little height, too much weight for their height compared with children in other countries, or both—occurred in many countries in sub-Saharan Africa, New Zealand, and the USA for boys and girls; in Malaysia and some Pacific island nations for boys; and in Mexico for girls. Interpretation The height and BMI trajectories over age and time of school-aged children and adolescents are highly variable across countries, which indicates heterogeneous nutritional quality and lifelong health advantages and risks

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities(.)(1,2) This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity(3-6). Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017-and more than 80% in some low- and middle-income regions-was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing-and in some countries reversal-of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories.Peer reviewe

Development and validation of HERWIG 7 tunes from CMS underlying-event measurements

This paper presents new sets of parameters (“tunes”) for the underlying-event model of the HERWIG7 event generator. These parameters control the description of multiple-parton interactions (MPI) and colour reconnection in HERWIG7, and are obtained from a fit to minimum-bias data collected by the CMS experiment at s=0.9, 7, and 13Te. The tunes are based on the NNPDF 3.1 next-to-next-to-leading-order parton distribution function (PDF) set for the parton shower, and either a leading-order or next-to-next-to-leading-order PDF set for the simulation of MPI and the beam remnants. Predictions utilizing the tunes are produced for event shape observables in electron-positron collisions, and for minimum-bias, inclusive jet, top quark pair, and Z and W boson events in proton-proton collisions, and are compared with data. Each of the new tunes describes the data at a reasonable level, and the tunes using a leading-order PDF for the simulation of MPI provide the best description of the dat

Search for new particles in events with energetic jets and large missing transverse momentum in proton-proton collisions at root s=13 TeV

A search is presented for new particles produced at the LHC in proton-proton collisions at root s = 13 TeV, using events with energetic jets and large missing transverse momentum. The analysis is based on a data sample corresponding to an integrated luminosity of 101 fb(-1), collected in 2017-2018 with the CMS detector. Machine learning techniques are used to define separate categories for events with narrow jets from initial-state radiation and events with large-radius jets consistent with a hadronic decay of a W or Z boson. A statistical combination is made with an earlier search based on a data sample of 36 fb(-1), collected in 2016. No significant excess of events is observed with respect to the standard model background expectation determined from control samples in data. The results are interpreted in terms of limits on the branching fraction of an invisible decay of the Higgs boson, as well as constraints on simplified models of dark matter, on first-generation scalar leptoquarks decaying to quarks and neutrinos, and on models with large extra dimensions. Several of the new limits, specifically for spin-1 dark matter mediators, pseudoscalar mediators, colored mediators, and leptoquarks, are the most restrictive to date.Peer reviewe

Combined searches for the production of supersymmetric top quark partners in proton-proton collisions at root s=13 TeV

A combination of searches for top squark pair production using proton-proton collision data at a center-of-mass energy of 13 TeV at the CERN LHC, corresponding to an integrated luminosity of 137 fb(-1) collected by the CMS experiment, is presented. Signatures with at least 2 jets and large missing transverse momentum are categorized into events with 0, 1, or 2 leptons. New results for regions of parameter space where the kinematical properties of top squark pair production and top quark pair production are very similar are presented. Depending on themodel, the combined result excludes a top squarkmass up to 1325 GeV for amassless neutralino, and a neutralinomass up to 700 GeV for a top squarkmass of 1150 GeV. Top squarks with masses from 145 to 295 GeV, for neutralino masses from 0 to 100 GeV, with a mass difference between the top squark and the neutralino in a window of 30 GeV around the mass of the top quark, are excluded for the first time with CMS data. The results of theses searches are also interpreted in an alternative signal model of dark matter production via a spin-0 mediator in association with a top quark pair. Upper limits are set on the cross section for mediator particle masses of up to 420 GeV

Measurement of the top quark forward-backward production asymmetry and the anomalous chromoelectric and chromomagnetic moments in pp collisions at √s = 13 TeV

Abstract The parton-level top quark (t) forward-backward asymmetry and the anomalous chromoelectric (d̂ t) and chromomagnetic (μ̂ t) moments have been measured using LHC pp collisions at a center-of-mass energy of 13 TeV, collected in the CMS detector in a data sample corresponding to an integrated luminosity of 35.9 fb−1. The linearized variable AFB(1) is used to approximate the asymmetry. Candidate t t ¯ events decaying to a muon or electron and jets in final states with low and high Lorentz boosts are selected and reconstructed using a fit of the kinematic distributions of the decay products to those expected for t t ¯ final states. The values found for the parameters are AFB(1)=0.048−0.087+0.095(stat)−0.029+0.020(syst),μ̂t=−0.024−0.009+0.013(stat)−0.011+0.016(syst), and a limit is placed on the magnitude of | d̂ t| < 0.03 at 95% confidence level. [Figure not available: see fulltext.