534 research outputs found
Access to Services for New Americans with Intellectual and Developmental Disabilities: Building Capacity Through the Ramirez June Initiative
New Americans with intellectual and developmental disabilities (IDD) are a significantly underserved community in New York State (NY) facing complex barriers accessing IDD services and fully integrating into their communities. New American communities lack connections with IDD service systems and struggle to find culturally and linguistically accessible information about disability services and resources. New Americans may be fearful of engaging with service providers, especially if they lack lawful immigration status and are undocumented. In acknowledgement of these barriers, NY implemented an initiative to create a navigator model that is the first of its kind in the nation. The Initiative is named the Ramirez June Initiative (Initiative) which was created in 2019 to build capacity at the local and state level to better serve new Americans with IDD. In this article, we outline the background, context, and key components of this navigator model. By providing a comprehensive and detailed overview of the Initiative, we hope to support the model’s replication across the nation, while considering local strengths and needs
Assessing reproducibility for radiographic measurement of leg length inequality after total hip replacement
Leg length inequality (LLI) as a result of total hip replacement can cause considerable morbidity. Although LLI was described when the technique was popularised in the 1960s, it remains a significant challenge to arthroplasty surgeons. This study reviews the established practice for the measurement of LLI on plain antero-posterior radiograph, and compares these techniques to two methods used locally. The radiographs of 35 patients were measured using four techniques. All four methods yielded an interclass correlation co-efficient of ≥0.90 for inter reader reliability. This study shows that the four methods are comparable for reliability, while a composite method, measuring from the centre of femoral rotation to the inferior teardrop and then to the lesser trochanter, has the added advantage of providing extra information on component position as well as an overall measure of LLI
Superconductivity and single crystal growth of Ni0:05TaS2
Superconductivity was discovered in a Ni0:05TaS2 single crystal. A Ni0:05TaS2
single crystal was successfully grown via the NaCl/KCl flux method. The
obtained lattice constant c of Ni0:05TaS2 is 1.1999 nm, which is significantly
smaller than that of 2H-TaS2 (1.208 nm). Electrical resistivity and
magnetization measurements reveal that the superconductivity transition
temperature of Ni0:05TaS2 is enhanced from 0.8 K (2H-TaS2) to 3.9 K. The
charge-density-wave transition of the matrix compound 2H-TaS2 is suppressed in
Ni0:05TaS2. The success of Ni0:05TaS2 single crystal growth via a NaCl/KCl flux
demonstrates that NaCl/KCl flux method will be a feasible method for single
crystal growth of the layered transition metal dichalcogenides.Comment: 13pages, 6 figures, Published in SS
Crucial Physical Dependencies of the Core-Collapse Supernova Mechanism
We explore with self-consistent 2D F{\sc{ornax}} simulations the dependence
of the outcome of collapse on many-body corrections to neutrino-nucleon cross
sections, the nucleon-nucleon bremsstrahlung rate, electron capture on heavy
nuclei, pre-collapse seed perturbations, and inelastic neutrino-electron and
neutrino-nucleon scattering. Importantly, proximity to criticality amplifies
the role of even small changes in the neutrino-matter couplings, and such
changes can together add to produce outsized effects. When close to the
critical condition the cumulative result of a few small effects (including
seeds) that individually have only modest consequence can convert an anemic
into a robust explosion, or even a dud into a blast. Such sensitivity is not
seen in one dimension and may explain the apparent heterogeneity in the
outcomes of detailed simulations performed internationally. A natural
conclusion is that the different groups collectively are closer to a realistic
understanding of the mechanism of core-collapse supernovae than might have
seemed apparent.Comment: 25 pages; 10 figure
Endocrine Therapy Nonadherence and Discontinuation in Black and White Women
Background: Differential use of endocrine therapy (ET) by race may contribute to breast cancer outcome disparities, but racial differences in ET behaviors are poorly understood. Methods: Women aged 20-74 years with a first primary, stage I-III, hormone receptor-positive (HR+) breast cancer were included. At 2 years postdiagnosis, we assessed nonadherence, defined as not taking ET every day or missing more than two pills in the past 14 days, discontinuation, and a composite measure of underuse, defined as either missing pills or discontinuing completely. Using logistic regression, we evaluated the relationship between race and nonadherence, discontinuation, and overall underuse in unadjusted, clinically adjusted, and socioeconomically adjusted models. Results: A total of 1280 women were included; 43.2% self-identified as black. Compared to white women, black women more often reported nonadherence (13.7% vs 5.2%) but not discontinuation (10.0% vs 10.7%). Black women also more often reported the following: hot flashes, night sweats, breast sensitivity, and joint pain; believing that their recurrence risk would not change if they stopped ET; forgetting to take ET; and cost-related barriers. In multivariable analysis, black race remained statistically significantly associated with nonadherence after adjusting for clinical characteristics (adjusted odds ratio = 2.72, 95% confidence interval = 1.75 to 4.24) and after adding socioeconomic to clinical characteristics (adjusted odds ratio = 2.44, 95% confidence interval = 1.50 to 3.97) but was not independently associated with discontinuation after adjustment. Low recurrence risk perception and lack of a shared decision making were strongly predictive of ET underuse across races. Conclusions: Our results highlight important racial differences in ET-Adherence behaviors, perceptions of benefits/harms, and shared decision making that may be targeted with culturally tailored interventions
Measurement of the Bottom-Strange Meson Mixing Phase in the Full CDF Data Set
We report a measurement of the bottom-strange meson mixing phase \beta_s
using the time evolution of B0_s -> J/\psi (->\mu+\mu-) \phi (-> K+ K-) decays
in which the quark-flavor content of the bottom-strange meson is identified at
production. This measurement uses the full data set of proton-antiproton
collisions at sqrt(s)= 1.96 TeV collected by the Collider Detector experiment
at the Fermilab Tevatron, corresponding to 9.6 fb-1 of integrated luminosity.
We report confidence regions in the two-dimensional space of \beta_s and the
B0_s decay-width difference \Delta\Gamma_s, and measure \beta_s in [-\pi/2,
-1.51] U [-0.06, 0.30] U [1.26, \pi/2] at the 68% confidence level, in
agreement with the standard model expectation. Assuming the standard model
value of \beta_s, we also determine \Delta\Gamma_s = 0.068 +- 0.026 (stat) +-
0.009 (syst) ps-1 and the mean B0_s lifetime, \tau_s = 1.528 +- 0.019 (stat) +-
0.009 (syst) ps, which are consistent and competitive with determinations by
other experiments.Comment: 8 pages, 2 figures, Phys. Rev. Lett 109, 171802 (2012
Energy metabolites as biomarkers in ischemic and dilated cardiomyopathy
With more than 25 million people affected, heart failure (HF) is a global threat. As energy production pathways are known to play a pivotal role in HF, we sought here to identify key metabolic changes in ischemic- and non-ischemic HF by using a multi-OMICS approach. Serum metabolites and mRNAseq and epigenetic DNA methylation profiles were analyzed from blood and left ventricular heart biopsy specimens of the same individuals. In total we collected serum from n = 82 patients with Dilated Cardiomyopathy (DCM) and n = 51 controls in the screening stage. We identified several metabolites involved in glycolysis and citric acid cycle to be elevated up to 5.7-fold in DCM (p = 1.7 × 10(-6)). Interestingly, cardiac mRNA and epigenetic changes of genes encoding rate-limiting enzymes of these pathways could also be found and validated in our second stage of metabolite assessment in n = 52 DCM, n = 39 ischemic HF and n = 57 controls. In conclusion, we identified a new set of metabolomic biomarkers for HF. We were able to identify underlying biological cascades that potentially represent suitable intervention targets
The TESS-Keck Survey. II. An Ultra-Short-Period Rocky Planet And Its Siblings Transiting The Galactic Thick-Disk Star TOI-561
We report the discovery of TOI-561, a multiplanet system in the galactic thick disk that contains a rocky, ultra-short-period planet. This bright (V = 10.2) star hosts three small transiting planets identified in photometry from the NASA TESS mission: TOI-561 b (TOI-561.02, P = 0.44 days, Rp = 1.45 ± 0.11 R⊕), c (TOI-561.01, P = 10.8 days, Rp = 2.90 ± 0.13 R⊕), and d (TOI-561.03, P = 16.3 days, Rp = 2.32 ± 0.16 R⊕). The star is chemically ([Fe/H] = −0.41 ± 0.05, [α/Fe] = +0.23 ± 0.05) and kinematically consistent with the galactic thick-disk population, making TOI-561 one of the oldest (10 ± 3 Gyr) and most metal-poor planetary systems discovered yet. We dynamically confirm planets b and c with radial velocities from the W. M. Keck Observatory High Resolution Echelle Spectrometer. Planet b has a mass and density of 3.2 ± 0.8 M⊕ and g cm−3, consistent with a rocky composition. Its lower-than-average density is consistent with an iron-poor composition, although an Earth-like iron-to-silicates ratio is not ruled out. Planet c is 7.0 ± 2.3 M⊕ and 1.6 ± 0.6 g cm−3, consistent with an interior rocky core overlaid with a low-mass volatile envelope. Several attributes of the photometry for planet d (which we did not detect dynamically) complicate the analysis, but we vet the planet with high-contrast imaging, ground-based photometric follow-up, and radial velocities. TOI-561 b is the first rocky world around a galactic thick-disk star confirmed with radial velocities and one of the best rocky planets for thermal emission studies
Thorium speciation in seawater
Author Posting. © The Authors, 2006. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Marine Chemistry 100 (2006): 250-268, doi:10.1016/j.marchem.2005.10.024.Since the 1960’s, thorium isotopes occupy a special place in the oceanographer’s toolbox as
tracers for determining rates and mechanisms of oceanic scavenging, particle dynamics, and
carbon fluxes. Due to their unique and constant production rates from soluble parent nuclides of
uranium and radium, their disequilibrium can be used to calculate rates and time scales of
sinking particles. In addition, by ratio-ing particulate 234Th (as well, in principle, other Thnuclides)
to carbon (and other elements), and linking this ratio to the parent-daughter
disequilibrium in the water column, it is possible to calculate fluxes of carbon and other
elements. Most of these applications are possible with little knowledge of the dissolved chemical
properties of thorium, other than its oxidation state (IV) and tendency to strongly sorb to
surfaces, i.e., its “particle- or surface-activity”. However, the use of any tracer is hindered by a
lack of knowledge of its chemical properties. Recent observations in the variability of carbon to
234Th ratios in different particle types, as well as of associations of Th(IV) with various marine
organic biomolecules has led to the need for a review of current knowledge and what future
endeavors should be taken to understand the marine chemistry of thorium.The writing of this paper was supported, in parts by NSF (OCE-0351559; OCE-0350758, and
OCE 0354757)
Coping with global uncertainty: Perceptions of COVID-19 psychological distress, relationship quality, and dyadic coping for romantic partners across 27 countries
- …