139 research outputs found

    “GĂ©oscola” or the short story of the implementation of a territorial geoportal as an assistance to public school management

    Get PDF
    La plateforme GĂ©oscola est nĂ©e de la nĂ©cessitĂ© de disposer d’un outil efficace pour le pilotage et l’aide Ă  la dĂ©cision de l’école publique du Canton du Valais. Sa crĂ©ation est le fruit d’une approche entre Sciences de l’éducation et GĂ©ographie. L’information sur le fonctionnement du systĂšme Ă©ducatif se construit Ă  partir des subdivisions administratives scolaires avec une perspective territoriale, grĂące Ă  l’adaptation du gĂ©oportail "GĂ©oclip Air", conçu pour et utilisĂ© par les instituts gĂ©ostatistiques. Cet article rend compte de l’aventure technique et humaine qu’a reprĂ©sentĂ© ce projet. Il analyse Ă©galement le processus ainsi initiĂ© avec diffĂ©rents acteurs institutionnels qui rend essentielle la priseen compte d’implications et d’exigences administratives, politiques et Ă©thiques sensibles. (DIPF/Orig.)The GĂ©oscola platform grew out of the need to have an effective tool for steering and helping decision-making in the public school system in the Canton of Valais. Its creation results of an approach between educational sciences and geography. Information on the structure of the school system is based on the nomenclature of educational subdivisions with a territorial perspective. This was achieved with the adaptation of “GĂ©oclip Air”, a geoportal designed and used primarily by statistical institutes. This article reports on the technical and human adventure this project represented. It also analyses the process thus initiated, in collaboration with various institutional actors, which makes it essential to consider sensitive administrative, political and ethical implications and requirements. (DIPF/Orig.

    framework of the ESPON 2013 Programme, partly financed by the European Regional Development Fund.

    Get PDF
    consists of the EU Commission and the Member States of the EU27, plus Iceland, Liechtenstein, Norway and Switzerland. Each partner is represented in the ESPON Monitoring Committee. This report does not necessarily reflect the opinion of the members of the Monitoring Committee. Information on the ESPON Programme and projects can be found on www.espon.eu The web site provides the possibility to download and examine the most recent documents produced by finalised and ongoing ESPON projects. This basic report exists only in an electroni

    Development Fund.

    Get PDF
    framework of the ESPON 2013 Programme, partly financed by the European Regiona

    Experimental Infection of Captive Red Foxes (Vulpes vulpes) with Mycobacterium bovis

    Get PDF
    [EN] In Europe, animal tuberculosis (TB) due to Mycobacterium bovis involves multi-host communities that include cattle and wildlife species, such as wild boar (Sus scrofa), badgers (Meles meles) and red deer (Cervus elaphus). Red fox (Vulpes vulpes) infections have also been recently reported in some TB endemic regions in the Iberian Peninsula and France, with some of the infected animals shedding M. bovis in urine and feces. In order to understand the pathogenesis of M. bovis infection in foxes and the associated risk of transmission, 12 captive foxes (6 females and 6 males) were inoc-ulated orally with 2 × 107 colony-forming units of a French field isolate of M. bovis. Clinical samples (urine, feces and oropharyngeal swabs) were collected every four weeks and tested for molecular diagnosis and bacteriology. Serological responses were measured by IDEXX M. bovis Ab Test and Multi Antigen Print Immunoassay (MAPIA). At a post-mortem examination performed 12 weeks post infection (wpi), tissues were tested for the presence of M. bovis and associated gross and microscopic TB-like lesions. M. bovis was detected by PCR in bladder swabs of 3 animals at 12 wpi. It was also detected pre-mortem at different time points of the experiment in the oropharyngeal mu-cus of three individuals and in the feces of nine foxes, with two of them confirmed by bacteriology. All 12 foxes had at least 4 PCR positive samples (out of the 23 tested), and all but 1 fox had at least 1 culture positive sample. The culture negative fox was PCR positive in both retropharyngeal and mesenteric lymph nodes, in line with the results of the other animals. Seroconversion was observed in all foxes except one during the experiment, and in nine at the final time point. No gross visible lesions were found in any animal at the post-mortem examination. The histology showed small granulomas within the lymph nodes, tonsils, liver and lungs from eight animals, with the presence of few acid-fast bacilli. These results confirmed that all orally-infected foxes developed mild TB lesions but they were able to shed mycobacteria in about 75% of cases, 1 month post-infection (9 out 12 foxes). These results show that it is possible to induce typical TB infection experimentally in captive foxes, with measurable M. bovis excretion; such an experimental system could be useful for future evaluations of diagnostics and vaccines in this speciesSIThe French Ministry of Agriculture mainly financed the sampling and the analyses in the framework of the RFSA call on TB projects (Anses-DGAl credit agreement RFSA 2017-326). The animals and the running cost of the BSL3 facilities and technical resources were financed by the European Commission in the context of Horizon 2020?Vetbionet Transnational Access Activities (TNA) call. This work is also partially the result of the I+D+i research project RTI2018-096010-B-C21, funded by the Spanish MCIN/AEI/10.13039/501100011033/ Ministry of Science, Innovation and the European Regional Development Funds (FEDER Una manera de hacer Europa), and of PCTI 2021? 2023 (GRUPIN: IDI2021-000102) funded by Principado de Asturias and FEDE

    The poetry of Celtic places

    Get PDF
    This paper examines the radical shift in the place of Celts in the French imagination during the course of the nineteenth century, by focusing on two versions of a passage describing Wales by Michelet: the first written in his travel journal (1834), the second published by his widow (1893). Wales, by virtue of being a Celtic place, allows Michelet to deepen his understanding of France. Whereas juxtaposition of the two versions of his text reveals something of the French state’s attitude toward the ambiguously domestic and exotic Celtic “other.

    Writing in Britain and Ireland, c. 400 to c. 800

    Get PDF
    No abstract available

    Introduction of SARS in France, March–April, 2003

    Get PDF
    We describe severe acute respiratory syndrome (SARS) in France. Patients meeting the World Health Organization definition of a suspected case underwent a clinical, radiologic, and biologic assessment at the closest university-affiliated infectious disease ward. Suspected cases were immediately reported to the Institut de Veille Sanitaire. Probable case-patients were isolated, their contacts quarantined at home, and were followed for 10 days after exposure. Five probable cases occurred from March through April 2003; four were confirmed as SARS coronavirus by reverse transcription–polymerase chain reaction, serologic testing, or both. The index case-patient (patient A), who had worked in the French hospital of Hanoi, Vietnam, was the most probable source of transmission for the three other confirmed cases; two had been exposed to patient A while on the Hanoi-Paris flight of March 22–23. Timely detection, isolation of probable cases, and quarantine of their contacts appear to have been effective in preventing the secondary spread of SARS in France

    How 'dynasty' became a modern global concept : intellectual histories of sovereignty and property

    Get PDF
    The modern concept of ‘dynasty’ is a politically-motivated modern intellectual invention. For many advocates of a strong sovereign nation-state across the nineteenth and early twentieth century, in France, Germany, and Japan, the concept helped in visualizing the nation-state as a primordial entity sealed by the continuity of birth and blood, indeed by the perpetuity of sovereignty. Hegel’s references to ‘dynasty’, read with Marx’s critique, further show how ‘dynasty’ encoded the intersection of sovereignty and big property, indeed the coming into self-consciousness of their mutual identification-in-difference in the age of capitalism. Imaginaries about ‘dynasty’ also connected national sovereignty with patriarchal authority. European colonialism helped globalize the concept in the non-European world; British India offers an exemplar of ensuing debates. The globalization of the abstraction of ‘dynasty’ was ultimately bound to the globalization of capitalist-colonial infrastructures of production, circulation, violence, and exploitation. Simultaneously, colonized actors, like Indian peasant/‘tribal’ populations, brought to play alternate precolonial Indian-origin concepts of collective regality, expressed through terms like ‘rajavamshi’ and ‘Kshatriya’. These concepts nourished new forms of democracy in modern India. Global intellectual histories can thus expand political thought today by provincializing and deconstructing Eurocentric political vocabularies and by recuperating subaltern models of collective and polyarchic power.PostprintPeer reviewe

    Staphylococcus aureus infective endocarditis versus bacteremia strains: Subtle genetic differences at stake

    Get PDF
    AbstractInfective endocarditis (IE)(1) is a severe condition complicating 10–25% of Staphylococcus aureus bacteremia. Although host-related IE risk factors have been identified, the involvement of bacterial features in IE complication is still unclear. We characterized strictly defined IE and bacteremia isolates and searched for discriminant features. S. aureus isolates causing community-acquired, definite native-valve IE (n=72) and bacteremia (n=54) were collected prospectively as part of a French multicenter cohort. Phenotypic traits previously reported or hypothesized to be involved in staphylococcal IE pathogenesis were tested. In parallel, the genotypic profiles of all isolates, obtained by microarray, were analyzed by discriminant analysis of principal components (DAPC)(2). No significant difference was observed between IE and bacteremia strains, regarding either phenotypic or genotypic univariate analyses. However, the multivariate statistical tool DAPC, applied on microarray data, segregated IE and bacteremia isolates: IE isolates were correctly reassigned as such in 80.6% of the cases (C-statistic 0.83, P<0.001). The performance of this model was confirmed with an independent French collection IE and bacteremia isolates (78.8% reassignment, C-statistic 0.65, P<0.01). Finally, a simple linear discriminant function based on a subset of 8 genetic markers retained valuable performance both in study collection (86.1%, P<0.001) and in the independent validation collection (81.8%, P<0.01). We here show that community-acquired IE and bacteremia S. aureus isolates are genetically distinct based on subtle combinations of genetic markers. This finding provides the proof of concept that bacterial characteristics may contribute to the occurrence of IE in patients with S. aureus bacteremia
    • 

    corecore