Messages to Eleanor Snell From the Class of 1962

These messages from the Ursinus College Class of 1962 congratulate Eleanor Snell on the occasion of her retirement from Ursinus College. They are written in ink on the back of gift wrapping paper.https://digitalcommons.ursinus.edu/snell_docs/1081/thumbnail.jp

The Ursinus Weekly, May 7, 1962

Curtain Club\u27s The Girls in 509 scheduled Friday and Saturday • Fraser & Dingman selected head soph rulers to enliven \u2762 frosh customs program • Canterbury Club features speaker, CBS church film • Awards highlight waiters\u27 banquet • Dennis recovering from heart attack • Moyer attends ISC meeting at E-town • World traveler slated to address IRC tonight • Yippee-i-o theme of Spring Festival featuring queen, festivities Saturday • Campus politicers reconcile riffs at annual banquet • Hudnut & students plan jazz seminar • Cub & Key Society meets at Staigers • Editorial: Beauty versus popularity; Turning the tables • Shenanigan \u2762 senior show theme • Dozing technique requires practice • Sesquicentennial fetes continue in nearby Norristown • Obscurity, neglect & confusion mark UC\u27s undeveloped college museum • Tennismen win over LaSalle, drop PMC heartbreaker • Lacrossers swamp West Chesterettes • Baseballers smash Haverford, F&M, lose to E-Towners • Trackmen trounce PMC & Dickinson, upset by Hopkins • UC & West Chester swap wins to open softball season • Greek gleaningshttps://digitalcommons.ursinus.edu/weekly/1319/thumbnail.jp

Pathogenicity phenomena in three model systems: from network mining to emerging system-level properties

Understanding the interconnections of microbial pathogenicity phenomena, such as biofilm formation, quorum sensing and antimicrobial resistance, is a tremendous open challenge for biomedical research. Progress made by wet-lab researchers and bioinformaticians in understanding the underlying regulatory phenomena has been significant, with converging evidence from multiple high-throughput technologies. Notably, network reconstructions are already of considerable size and quality, tackling both intracellular regulation and signal mediation in microbial infection. Therefore, it stands to reason that in silico investigations would play a more active part in this research. Drug target identification and drug repurposing could take much advantage of the ability to simulate pathogen regulatory systems, hostpathogen interactions and pathogen cross-talking. Here, we review the bioinformatics resources and tools available for the study of the gram-negative bacterium Pseudomonas aeruginosa, the gram-positive bacterium Staphylococcus aureus and the fungal species Candida albicans. The choice of these three microorganisms fits the rationale of the review converging into pathogens of great clinical importance, which thrive in biofilm consortia and manifest growing antimicrobial resistance.IBB - Institute for Biotechnology and Bioengineering, CEB - Centre of Biological Engineering; Fundacao para a Ciencia e Tecnologia (FCT); the European Community fund FEDER, through Program COMPETE, in the ambit of the FCT Project PTDC/SAU-SAP/113196/2009/FCOMP-01-0124-FEDER-016012; the European Union Seventh Framework Programme [FP7/REGPOT-2012-2013.1] under grant agreement no 316265, BIOCAPS; the Agrupamento INBIOMED from DXPCTSUG-FEDER unha maneira de facer Europa (2012/273); the ERASMUS program of scholarships