63 research outputs found
Factors Behind the Higher COVID-19 Risk in Diabetes: A Critical Review
- Author
- Publication venue
- Frontiers Media
- Publication date
- 01/01/2021
- Field of study
Diabetes mellitus (DM) and coronavirus disease 2019 (COVID-19) are public health issues worldwide, and their comorbidities trigger the progress to severe disease and even death in such patients. Globally, DM has affected an estimated 9.3% adults, and as of April 18, 2021, the World Health Organization (WHO) has confirmed 141,727,940 COVID-19 confirmed cases. The virus is spread via droplets, aerosols, and direct touch with others. Numerous predictive factors have been linked to COVID-19 severity, including impaired immune response and increased inflammatory response, among others. Angiotensin receptor blockers and angiotensin converting enzyme 2 have also been identified as playing a boosting role in both susceptibility and severity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Specifically, in DM patients, both their control and management during this pandemic is herculean as the restriction periods have markedly hampered the maintenance of means to control glycemia, hypertension, and neuroendocrine and kidney diseases. In addition, as a result of the underlyin cardio-metabolic and immunological disorders, DM patients are at a higher risk of developing the severe form of COVID-19 despite other comorbidities, such as hypertension, also potentially boosting the development of higher COVID-19 severity. However, even in non-DM patients, SARS-CoV-2 may also cause transient hyperglycemia through induction of insulin resistance and/or pancreatic Ă-cell injury. Therefore, a strict glucose monitoring of DM patients with COVID-19 is mandatory to prevent life-threatening complications.NC-M acknowledges the Portuguese Foundation for Science and Technology under the Horizon 2020 Program (PTDC/PSI-GER/28076/2017)
Photodynamic therapy for multi-resistant cutaneous Langerhans cell histiocytosis
- Author
- Allen CE
- Annemans L
- Arjen F Nikkels
- Berman B
- Broadbent V
- Broekaert SM
- Caekelbergh K
- Chang SE
- Hoeger PH
- Hussein MR
- Jordan MB
- Kwon OS
- Lau L
- Marie Caucanas
- McClain KL
- Nazli Nikkels-Tassoudji
- Neumann C
- Nikkels AF
- O'Kane D
- Odile Wauters
- Querings K
- Sander CS
- Satter EK
- Sheehan MP
- Steen AE
- Valérie Failla
- von Stebut E
- Wauters O
- Zeitouni NC
- Publication venue
- PagePress
- Publication date
- 29/04/2010
- Field of study
Langerhans cell histiocytosis is a rare group of proliferative disorders. Beside cutaneous involvement, other internal organs can be affected. The treatment of cutaneous lesions is difficult and relies on topical corticosteroids, carmustine, nitrogen mustard, and photochemotherapy. Systemic steroids and vinblastine are used for recalcitrant skin lesions. However, some cases fail to respond. An 18-month old boy presented a CD1a+, S100a+ Langerhans cell histocytosis with cutaneous and severe scalp involvement. Topical corticosteroids and nitrogen mustard failed to improve the skin lesions. Systemic corticosteroids and vinblastine improved the truncal involvement but had no effect on the scalp lesions. Methylaminolevulinate (MAL) based photodynamic therapy (PDT) resulted in a significant regression of the scalp lesions. Control histology revealed an almost complete clearance of the tumor infiltrate. Clinical follow-up after six months showed no recurrence
Measurement of the Bottom-Strange Meson Mixing Phase in the Full CDF Data Set
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- Shintani T
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- Soldati T
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- Song X
- Sood AK
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- Sotgia F
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- Spies CD
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- Squillacioti
- Srinivasula SM
- St. Denis
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- Stefanis L
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- Stelzer
- Stelzer-Chilton
- Stendel R
- Stenmark H
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- Stephanou A
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- Strologas
- Strycker
- StrÄlfors P
- Subauste CS
- Sudo
- Sui X
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- Sulzer D
- Sun SY
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- Trovato
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- Velev
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- W.
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- Wicklund
- Wicklund
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- Williams
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- Wittich
- Wolbers
- Wolfe
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- X.
- Y.
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- Yamamoto
- Yamato
- Yang
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- Yao
- Yeh
- Yi
- Yoh
- Yorita
- Yoshida
- Yu
- Yu
- Yu
- Yun
- Z.
- Zanetti
- Zeng
- Zhou
- Zucchelli
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
We report a measurement of the bottom-strange meson mixing phase \beta_s
using the time evolution of B0_s -> J/\psi (->\mu+\mu-) \phi (-> K+ K-) decays
in which the quark-flavor content of the bottom-strange meson is identified at
production. This measurement uses the full data set of proton-antiproton
collisions at sqrt(s)= 1.96 TeV collected by the Collider Detector experiment
at the Fermilab Tevatron, corresponding to 9.6 fb-1 of integrated luminosity.
We report confidence regions in the two-dimensional space of \beta_s and the
B0_s decay-width difference \Delta\Gamma_s, and measure \beta_s in [-\pi/2,
-1.51] U [-0.06, 0.30] U [1.26, \pi/2] at the 68% confidence level, in
agreement with the standard model expectation. Assuming the standard model
value of \beta_s, we also determine \Delta\Gamma_s = 0.068 +- 0.026 (stat) +-
0.009 (syst) ps-1 and the mean B0_s lifetime, \tau_s = 1.528 +- 0.019 (stat) +-
0.009 (syst) ps, which are consistent and competitive with determinations by
other experiments.Comment: 8 pages, 2 figures, Phys. Rev. Lett 109, 171802 (2012
Diabetes mellitus type 2 and other chronic non-communicable diseases in the central region, Saudi Arabia (riyadh cohort 2): a decade of an epidemic
- Author
- A Alzaid
- A Cole
- AR Al-Nuaim
- AS Al-Rethaiaa
- AS Aljoudi
- AS Warsy
- AV Chobanian
- B Falkner
- CL Gilles
- DM Nathan
- FA Al-Hussein
- GA Wilson
- George P Chrousos
- GP Chrousos
- HH Fatani
- HW Rodbard
- JE Shaw
- K Yamaoka
- Khalid M Alkharfy
- M El-Hazmi
- MA Al-Rowailly
- MA El-Hazmi
- Majed S Alokail
- Mansour Yousef
- MM Al-Nozha
- MM Al-Nozha
- MM Al-Nozha
- MM Al-Nozha
- MM Al-Nozha
- MM Bassiony
- MY Elsammak
- N Al-Hamdan
- Nasser M Al-Daghri
- NM Al-Daghri
- NM Al-Daghri
- NM Al-Daghri
- NM Al-Daghri
- NM Al-Daghri
- NM Al-Daghri
- NM Bawazeer
- Omar S Al-Attas
- OS Al-Attas
- P Zhang
- S Wild
- Shaun Louie Sabico
- TA Elhadd
- TJ Cole
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
<p>Abstract</p> <p>Background</p> <p>Follow-up epidemiologic studies are needed to assess trends and patterns of disease spread. No follow-up epidemiologic study has been done in the Kingdom of Saudi Arabia to assess the current prevalence of major chronic, noncommunicable diseases, specifically in the urban region, where modifiable risk factors remain rampant. This study aims to fill this gap.</p> <p>Methods</p> <p>A total of 9,149 adult Saudis ages seven to eighty years (5,357 males (58.6%) and 3,792 females (41.4%)) were randomly selected from the Riyadh Cohort Study for inclusion. Diagnosis of type 2 diabetes mellitus (DMT2) and obesity were based on the World Health Organization definitions. Diagnoses of hypertension and coronary artery disease (CAD) were based on the Seventh Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure and American Heart Association criteria, respectively.</p> <p>Results</p> <p>The overall crude prevalence of DMT2 was 23.1% (95% confidence interval (95% CI) 20.47 to 22.15). The age-adjusted prevalence of DMT2 was 31.6%. DMT2 prevalence was significantly higher in males, with an overall age-adjusted prevalence of 34.7% (95% CI 32.6 to 35.4), than in females, who had an overall age-adjusted prevalence of 28.6% (95% CI 26.7 to 29.3) (<it>P </it>< 0.001). The overall crude prevalence of obesity was 31.1% (95% CI 30.1 to 32.0). The age-adjusted prevalence of obesity was 40.0%. The prevalence of obesity was higher in females, with an overall prevalence of 36.5% (95% CI 35.1 to 37.83), than in males (25.1% (95% CI 23.7 to 26.3)) (<it>P </it>< 0.001). The age-adjusted prevalence of hypertension and CAD were 32.6% (95% CI 31.7 to 33.6) and 6.9% (95% CI 6.4 to 7.4), respectively.</p> <p>Conclusion</p> <p>Comparisons of our findings with earlier data show that the prevalence of DMT2, hypertension and CAD in Riyadh, Saudi Arabia, has alarmingly worsened. Aggressive promotion of public awareness, continued screening and early intervention are pivotal to boosting a positive response.</p
Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study.
- Author
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- Abd El Hameed OS
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- Abd-Elrasoul Y
- Abdallah E
- Abdel-Wahab NYE
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- Zardab A
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- Zerihun AB
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
BACKGROUND: Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in the availability of laparoscopic appendectomy, alternative management choices, and outcomes are poorly described. The aim was to identify variation in surgical management and outcomes of appendicitis within low-, middle-, and high-Human Development Index (HDI) countries worldwide. METHODS: This is a multicenter, international prospective cohort study. Consecutive sampling of patients undergoing emergency appendectomy over 6Â months was conducted. Follow-up lasted 30Â days. RESULTS: 4546 patients from 52 countries underwent appendectomy (2499 high-, 1540 middle-, and 507 low-HDI groups). Surgical site infection (SSI) rates were higher in low-HDI (OR 2.57, 95% CI 1.33-4.99, pâ=â0.005) but not middle-HDI countries (OR 1.38, 95% CI 0.76-2.52, pâ=â0.291), compared with high-HDI countries after adjustment. A laparoscopic approach was common in high-HDI countries (1693/2499, 67.7%), but infrequent in low-HDI (41/507, 8.1%) and middle-HDI (132/1540, 8.6%) groups. After accounting for case-mix, laparoscopy was still associated with fewer overall complications (OR 0.55, 95% CI 0.42-0.71, pâ<â0.001) and SSIs (OR 0.22, 95% CI 0.14-0.33, pâ<â0.001). In propensity-score matched groups within low-/middle-HDI countries, laparoscopy was still associated with fewer overall complications (OR 0.23 95% CI 0.11-0.44) and SSI (OR 0.21 95% CI 0.09-0.45). CONCLUSION: A laparoscopic approach is associated with better outcomes and availability appears to differ by country HDI. Despite the profound clinical, operational, and financial barriers to its widespread introduction, laparoscopy could significantly improve outcomes for patients in low-resource environments. TRIAL REGISTRATION: NCT02179112
Measuring routine childhood vaccination coverage in 204 countries and territories, 1980-2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1
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- Velazquez DZ
- Vo B
- Vollmer S
- Waheed Y
- Winkler AS
- Wiysonge CS
- Yigit V
- Yirdaw BW
- Yon DK
- Yonemoto N
- Yu C
- Yuce D
- Yunusa I
- Zaki MES
- Zamani M
- Zamanian M
- Zewdie DT
- Zhang Z-J
- Zhong C
- Zumla A
- Publication venue
- ELSEVIER SCIENCE INC
- Publication date
- 07/08/2021
- Field of study
Background: Measuring routine childhood vaccination is crucial to inform global vaccine policies and programme implementation, and to track progress towards targets set by the Global Vaccine Action Plan (GVAP) and Immunization Agenda 2030. Robust estimates of routine vaccine coverage are needed to identify past successes and persistent vulnerabilities. Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020, Release 1, we did a systematic analysis of global, regional, and national vaccine coverage trends using a statistical framework, by vaccine and over time. //
Methods: For this analysis we collated 55â326 country-specific, cohort-specific, year-specific, vaccine-specific, and dose-specific observations of routine childhood vaccination coverage between 1980 and 2019. Using spatiotemporal Gaussian process regression, we produced location-specific and year-specific estimates of 11 routine childhood vaccine coverage indicators for 204 countries and territories from 1980 to 2019, adjusting for biases in country-reported data and reflecting reported stockouts and supply disruptions. We analysed global and regional trends in coverage and numbers of zero-dose children (defined as those who never received a diphtheria-tetanus-pertussis [DTP] vaccine dose), progress towards GVAP targets, and the relationship between vaccine coverage and sociodemographic development. //
Findings: By 2019, global coverage of third-dose DTP (DTP3; 81·6% [95% uncertainty interval 80·4â82·7]) more than doubled from levels estimated in 1980 (39·9% [37·5â42·1]), as did global coverage of the first-dose measles-containing vaccine (MCV1; from 38·5% [35·4â41·3] in 1980 to 83·6% [82·3â84·8] in 2019). Third-dose polio vaccine (Pol3) coverage also increased, from 42·6% (41·4â44·1) in 1980 to 79·8% (78·4â81·1) in 2019, and global coverage of newer vaccines increased rapidly between 2000 and 2019. The global number of zero-dose children fell by nearly 75% between 1980 and 2019, from 56·8 million (52·6â60·9) to 14·5 million (13·4â15·9). However, over the past decade, global vaccine coverage broadly plateaued; 94 countries and territories recorded decreasing DTP3 coverage since 2010. Only 11 countries and territories were estimated to have reached the national GVAP target of at least 90% coverage for all assessed vaccines in 2019. //
Interpretation: After achieving large gains in childhood vaccine coverage worldwide, in much of the world this progress was stalled or reversed from 2010 to 2019. These findings underscore the importance of revisiting routine immunisation strategies and programmatic approaches, recentring service delivery around equity and underserved populations. Strengthening vaccine data and monitoring systems is crucial to these pursuits, now and through to 2030, to ensure that all children have access to, and can benefit from, lifesaving vaccines
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
- Author
- Abantanga FA
- Abatli SJ
- Abbas W
- Abbo O
- Abd Elmenam M
- Abd Razak RB
- Abdelbaqi R
- Abdelhady DS
- Abdelhafez MOM
- Abdelhamid SS
- Abdelmaksoud S
- Abdelmoumen R
- Abdelmutalib F
- Abdul-Mumin A
- Abduljawad FM
- Abdullah F
- Abdulraheem N
- Abdulrahman A
- Abdulsalam MA
- Abdunomonovich DA
- Abib SDCV
- Aboelela A
- Abouheba M
- Abrahamsson K
- Abu Ajwa AE
- Abu Al-saleem HSH
- Abu Alamrain AA
- Abu Bakar AH
- Abu Farha MS
- Abu Jamie N
- Abu Jamie YMK
- Abu Jayyab M
- Abu Mayaleh A
- Abu Shiha E
- Abu Za'nouneh FJ
- Abu-Nejmah F
- Abuajaila A
- Abuattaya AA
- Abubakar AM
- Abueideh A
- Abuhayyeh HA
- Abuhlega MA
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- Abumunshar AA
- Acuna G
- Adams S
- Adamu S
- Adanan MFSBM
- Adawi I
- Adawi S
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- Al Massry NA
- Al Quran TM
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- Zreeg DAS
- Zurikat RO
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- Zvizdic Z
- Publication venue
- ELSEVIER SCIENCE INC
- Publication date
- 24/07/2021
- Field of study
Background: Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. // Methods: We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung's disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. // Findings: We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung's disease) from 264 hospitals (89 in high-income countries, 166 in middle-income countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36â39) and median bodyweight at presentation was 2·8 kg (2·3â3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in low-income countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; pâ€0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88â4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59â2·79], p<0·0001), sepsis at presentation (1·20 [1·04â1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4â5 vs ASA 1â2, 1·82 [1·40â2·35], p<0·0001; ASA 3 vs ASA 1â2, 1·58, [1·30â1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02â1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41â2·71], p=0·0001; parenteral nutrition 1·35, [1·05â1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47â0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50â0·86], p=0·0024) or percutaneous central line (0·69 [0·48â1·00], p=0·049) were associated with lower mortality. // Interpretation: Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between low-income, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030
The global burden of cancer attributable to risk factors, 2010-19: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Aali A
- Ab Khan M
- Abbas Q
- Abbasi B
- Abbasi-Kangevari M
- Abbasi-Kangevari Z
- Abbastabar H
- Abd-Elsalam S
- Abdelmasseh M
- Abdelwahab AA
- Abdoli G
- Abdulkader RS
- Abdulkadir HA
- AbdulmuhsinMohammad K
- Abedi A
- Abegaz KH
- Abidi H
- Aboagye RG
- Abolhassani H
- Absalan A
- Abtew YD
- Abu-Gharbieh E
- Achappa B
- Acheson AR
- Acuna JM
- Addison D
- Addo IY
- Adegboye OA
- Adesina MA
- Adnan M
- Adnani QES
- Advani SM
- Afrin S
- Afzal MS
- Aggarwal M
- Ahinkorah BO
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- Ahmadi S
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- Akalu GT
- Akbarzadeh-Khiavi M
- Aklilu A
- Akonde M
- Akunna CJ
- Al Hamad H
- Al Montasir A
- Al-Hanawi MK
- Al-Maweri SAA
- Al-Raddadi RM
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- Nassereldine H
- Natto ZS
- Navashenaq JG
- Nayak BP
- Ndejjo R
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- Silva LMLR
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- Sofi-Mahmudi A
- Solomon Y
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- Song Y
- Soodejani MT
- Sorensen RJD
- Soshnikov S
- Sotoudeh H
- Sowe A
- Sufiyan MB
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- Velazquez DZ
- Veroux M
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- Vladimirov SK
- Vlassov V
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- Woldemariam M
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- Yeshaw Y
- Yismaw Y
- Yonemoto N
- Younis MZ
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- Zarrintan A
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- Zodpey S
- Zoladl M
- Publication venue
- Publication date
- 20/08/2022
- Field of study
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
- Aahlin EK
- Aamer A
- Aaniana K
- Ababneh A
- Abaliksta T
- Abantanga F
- Abantanga F
- Abbas A
- Abbas M
- Abbasy J
- Abbo O
- Abbo O
- Abbott T
- Abbouch M
- Abd El Galeel A
- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
- Abdel-Aty A
- Abdel-Hameed N
- Abdel-Kader SM
- Abdel-Wahab NYE
- Abdelaal A
- Abdelaty M
- Abdelazeam AR
- Abdelazim G
- Abdelaziz MA
- Abdelbadeai K
- Abdelfatah A
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelhady S
- Abdelhamed R
- Abdelhamid A
- Abdelhaq A
- Abdelkader M
- Abdelkader M
- Abdelkader O
- Abdelkareem A
- Abdelkhalek M
- Abdelmageed E
- Abdelmotaleb I
- Abdelraheim M
- Abdelraouf AM
- Abdelrouf DM
- Abdelshafy M
- Abdelshakour M
- Abdrabou AK
- Abdul-Latif S
- Abdulaziz H
- Abdulaziz M
- Abdulbagi O
- Abdulgawad M
- Abdulhakeem EM
- Abdullah AAN
- Abdullah MA
- Abdullah N
- Abdullah NAN
- Abdullah NAN
- Abdullahi L
- Abdurrazzaaq A
- Abebe NS
- Abebe NS
- Abem OE
- Aber A
- Abington E
- Abiola O
- Aboarab A
- Aboelella M
- Aboelmagd O
- Aboelsoud MR
- Aboraya M
- Aboraya M
- Abouelnasr A
- Aboul-Naga MS
- Abouzahra A
- Abouzaid A
- Abozaid M
- Abozeid K
- Abozyed MAF
- Abu Qumbos A
- Abu-toyour M
- Abubakr M
- Abudeeb H
- Abuowda Y
- Abuqwaider E
- Abusalem L
- Abuseif M
- Abushamleh S
- Acharya P
- Ackom E
- Acquah E
- Adam A
- Adam N
- Adams R
- Adamu A
- Adawi I
- Adawi M
- Adebanjo A
- Adebanjo A
- Adebola O
- Adedeji A
- Adekoya A
- Adel A
- Adel A
- Adel BE
- Adel I
- Adella FJ
- Adelshone A
- Ademuyiwa A
- Ademuyiwa A
- Ademuyiwa AO
- Ademuyiwa AO
- Ademuyiwa AO
- Ademuyiwa AO
- Adenekan B
- Adeniran J
- Adeniran J
- Adeniyi A
- Adeniyi A
- Adesanya O
- Adesanya O
- Adesina A
- Adesina A
- Adesuyi A
- Adeyeye A
- Adeyeye A
- Adeyeye A
- Adham W
- Adhitama N
- Adil M
- Adisa AO
- Adisa AO
- Adu-Aryee N
- Afana S
- Afandy A
- Afifi AM
- Afzal M
- Agalianos C
- Agalianos C
- Agarwal A
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- Agius M
- Aglan A
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- Aguilera-Arevalo M-L
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- Ahlqvist S
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- Ahmed A
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- Ahounou EYS
- Aigrain Y
- Aiyaman C
- Ajah J
- Ajai O
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- Akatibo E
- Akeel N
- Akhtar M
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- Akpenyi O
- Al Amin S
- Al Attar SM
- Al Awwad S
- Al Barrawi FE
- Al Bastawis F
- Al Meligy A
- Al Rafati AAR
- Al Raouf EA
- Al Saied G
- Al Subaie N
- Al-Aarag AA-R
- Al-Azraqi IAA
- Al-Bahrani A
- Al-Buhaisi A
- Al-Dakka E
- Al-Faifi JJ
- Al-faqawi M
- Al-farram H
- Al-Hameedi HII
- Al-Hasani RKMJ
- Al-khatib A
- Al-Mallah A
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- Alaael-Dein S
- Alada M
- Alahmady O
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- Alaloul E
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- Albiety A
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- Aldalaq A
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- Alexander P
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- Alfarsi MA
- Alghamdi A
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- Alihonou T
- Alimi Q
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- Aliyu H
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- Aljboor K
- Aljiffry M
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- Aljohani E
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- Alkaaki A
- Alkammash A
- Alkelani M
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- Alkhouri M
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- Almoflihi A
- Almuallem S
- Almy J
- Alnaby MH
- Alnawam E
- Alnuqaydan SA
- Alnusairat A
- Alomar IN
- Alqahtani E
- Alqahtani S
- Alrahawy M
- Alrajraji M
- Alrifaie A
- AlRowais M
- Alsaggaf M
- Alsaggaf MU
- Alsaggaf MU
- Alser OH
- Alshareef R
- Altaf A
- Altaf A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamini A
- Altarayra M
- Althwainy A
- Altibi A
- Altinel Y
- Altinel Y
- Altoe F
- Altwigry AM
- Altwijri A
- Alvarado Jaramillo R
- Alvarez Barreda LM
- Alvi AR
- Alwafai MG
- Aly AK
- Aly MYM
- Alyacoubi S
- Alyahya R
- Alyami R
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- AlYoussef I
- Alzahrani A
- Alzahrani M
- Alzahrani M
- Alzayat T
- Aman NF
- Amandito R
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- Ambrozeviciute V
- Ameen M
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- Andika FFA
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- Antar S
- Antezana D
- Anthoulakis C
- Anthoulakis C
- Antoniozzi A
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- Anwer W
- Anyanwu L-J
- Anyanwu L-J
- Aonzo P
- Appeadu-Mensah W
- Appiah EK
- Aql S
- Aquilino F
- Arachchi PP
- Arachchige LAJJ
- Arafa O
- Arafa S
- Arango MCM
- Arango MCM
- Aranzabal Durand SY
- Araujo R
- Arcudi C
- Ardley R
- Arenas A
- Arevalo Azmitia JR
- Arias Pacheco RD
- Arman S
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- Armando ChunguiBravo J
- Armellini A
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- Arnaud AP
- Arnaud AP
- Arnaud AP
- Arroyo Basto CA
- Arshad MM
- Arslan E
- Arsyad HM
- Arthur T
- Arulampalam T
- Aruldas N
- Asal M
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- Asele FA
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- Asumah H
- Ata A
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- Atiyeh A
- Atkins ET
- Atkinson K
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- Attallah NA
- Attard M
- Attia A
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- Aung KP
- Austraite A
- Aviles S
- Avoka A
- Awad I
- Awad SA
- Awadallah S
- Awuku-Asabre J
- Ayad S
- Ayandipo O
- Ayandipo OO
- Aydin MC
- Ayyar S
- Aziz DNA
- Aziz MRA
- Aziz NA
- Azizeldine MG
- Azmitia Mendizabal CA
- Azodo IA
- Azzie G
- Azzie G
- Azzis O
- Baba S
- Bachri H
- Badawy M
- Badenjki MA
- Badicel M
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- Badr MFM
- Badwi NM
- Badwi NM
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- Bakhaidar M
- Baki BE
- Bakr A
- Bakry HM
- Bala M
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- Baldacchino M
- Balducci G
- Balila RMH
- Balkan AZA
- Ballouhey Q
- Balmaceda R
- Balmaceda R
- Balmaceda R
- Balogun F
- Baltrunas R
- Baluch F
- Bamford R
- Bamicha A
- Bamicha A
- Banaitis VJ
- Bandi A
- Bandoh D
- Bani-Sadar A
- Banipal GS
- Baraka H
- Barakat SAE
- Barendegere V
- Barker T
- Barkolias C
- Barmayehvar B
- Barnabas GN
- Barnacle J
- Barneo L
- Barrionuevo Ojeda RR
- Barrios E
- Barrios E
- Barros De Castro Segundo LC
- Barroso de Lima CV
- Barry J
- Basilico S
- Basir ERM
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- Bassit KA
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- Bekhet NM
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- Belkouchi A
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- Benevento A
- Benevento A
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- Benons N
- Bentounsi Z
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- Bertuello I
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- Bezzina M
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- Bhargava A
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- Bhopal KF
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- Bianco F
- Bigaran A
- Billy M
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- Cheung YHE
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- Chidambaram S
- Chiesa D
- Chilton G
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- Choi J
- Choi P
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- Chong CL
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- Chong HY
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- Chowdhury A
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- Mahmoud MI
- Mahmoud S
- Mahmoud SME
- Mahmud K
- Maillot B
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- Maison K
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- Mak T
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- Makinde M
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- Malaga B
- Malavenda M
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- Mamdouh E
- Mamdouh R
- Manatakis DK
- Manchego Bautista AC
- Manchego Bautista AC
- Manfreda S
- Mangan C
- Mangan C
- Mangiapane M
- Manipal CE
- Maniscalco A
- Mann T
- Mannu GS
- Mano MJB
- Manrique Sila G
- Manrique Sila GC
- Manriquez-Reyes M
- Manrrique Sila G
- Mansor EY
- Mansour B
- Mansour S
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- Mariani A
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- Marroquin Rodriguez DE
- Marshall DC
- Martian B-V
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- Mas R
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- Mathew SW
- Matos-Puig R
- Mattar O
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- Menegussi J
- Mensah E
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- Mentula P
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- Merlo MS
- Mesbah N
- Meshref A
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- Metwally MM
- Migliore M
- Mihaljevic AL
- Mihaljevic AL
- Mihanovic J
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- Minguez Garcia J
- Minguez G
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- Miranda C
- Mircea H
- Mirghani D
- Mironescu A
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- Mironescu AS
- Mironescu AS
- Mirza A
- Mirza S
- Mistry A
- Mitrasinovic S
- Mitroudi M
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- Mizzi C
- Mizzi S
- Mlotshwa M
- Moaty M
- Mochet S
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- Modolo MM
- Modolo MM
- Moe TT
- Mogan YP
- Moghazy ME
- Mohamed A
- Mohamed A
- Mohamed AM
- Mohamed AR
- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed MA
- Mohamed MAEH
- Mohamed MM
- Mohamed O
- Mohamed SR
- Mohameden A
- Mohammad A
- Mohammad A
- Mohammed A
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- Mohammed AR
- Mohammed H
- Mohammed MM
- Mohammed MMH
- Mohammed S
- Mohan H
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- Monrad-Hansen PW
- Monteleone M
- Monteleone M
- Montes I
- Montes I
- Montoya Botero JA
- Montrimaite M
- Montrimaite M
- Moodley Y
- Moore R
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- Mora JJV
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- Morandi E
- Moreira G
- Moreno SC
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- Morsi A
- Morsi M
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- Morton R
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- Mosalum O
- Mostafa HA
- Mostafa M
- Mostafa M
- Mousa M
- Moussa O
- Moustafa A
- Mouttalib S
- Mowafy B
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- Mshelbwala P
- Msiska N
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- Muktar U
- Mukuzunga C
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- Munipalle PC
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- Musowoya J
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- Mutlu V
- Muzio E
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- Nanthakumaran S
- Napolitano L
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- Naqvi SA
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- Naranjo Aristizaibal FA
- Narayanan R
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- Narvestad JK
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- Natili A
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- Nazir M
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- Ndlovu SR
- Ndwambi P
- Negida A
- Negoi I
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- Nepogodiev D
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- Nevieraite V
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- Niranjan N
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- Njokanma I
- Nnajiuba H
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- Nofal E
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- Noukpozounkou B
- Novak A
- Nowers J
- Nsengimana VJP
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- Nurqistan HD
- Nwabuoku E
- Nwinee V
- Nwokoro C
- Nyberg J
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- Palomino Castillo VD
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- Papaskarlatos I-A
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- Perez Velasquez CI
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- Pesenti G
- Petrikenas S
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- Phillips N
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- Picciariello A
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- Pinkney T
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- Preckailaite E
- Primavesi F
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- Punja V
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- Qureshi AU
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- Ramarez Cabrera CC
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- Razi SAU
- Razmdjou S
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- Samaraweera DI
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- Sandoval Barrantes AM
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- Senanayake KJ
- Senanayake WSMKJ
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- Shahbaz AR
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- Snyder E
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- Sobnach S
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- Soeselo DA
- Sokratous A
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- Solar Garcia L
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- Soldevila-Verdeguer C
- Soley R
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- Soltani N
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- Staerkle RF
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- Stefanopoulos A
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- Sundstrom SM
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- Taddei A
- Tade A
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- Taha EMS
- Tahboub H
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- Taieb C
- Taiwo A
- Taiwo O
- Taiwo O
- Talaat M
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- Tammam A
- Tan C
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- Tan CY
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- Tan JK
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- Tan YK
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- Tanase A
- Tang A
- Tang L
- Tani SI
- Tansoker I
- Tarek A
- Tarek A
- Tarek D
- Targa S
- Tariq S
- Tata MD
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- Tedeschi U
- Tedjaatmadja C
- Telfah MM
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- Tennakoon A
- Teo SY
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- Thabet W
- Thalgaspitiya SPB
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- Theodosopoulos T
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- Ukwenya Y
- Ulusahin M
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- Zuber M
- Zuber M
- Zuk G
- Zulkifli A
- Zumbuhl L
- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic
- Author
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- Sorribas Grifell M.
- Soto Montesinos C. (FundaciĂł Althaia â Xarxa Assistencial UniversitĂ ria de Manresa)
- Souadka A. (Institut National dâOncologie
- Soulikia K.
- Sousa Fernandes M. (Hospital Beatriz Angelo)
- Sousa R. (Centro Hospitalar UniversitĂĄrio Lisboa Central)
- Sousa S.
- Spagni G.
- Spampinato M. G. (Vito Fazzi
- Spartalis E.
- Spencer N.
- Spiezio G. (Colorectal Surgical Oncology Unit â Istituto Nazionale Tumori Fondazione
- Spinelli A. (Humanitas Clinical and Research Center IRCCS
- Sreedharan L.
- Sriram R. K.
- Srishankar S. (Teaching Hospital Anuradhapura). Sudan Ali Adil A. K. (Al-Rajhi). COVIDSurg COllabOratIVe | 17 Sweden: ĂlgĂ„ A.
- St John S.
- Stafford J. (George Eliot Hospital)
- Stavrinidou O.
- Steele C. (Sheffield Teaching Hospital NHS Foundation Trust)
- Steidle C.
- Steinke J.
- Stevens K.
- Stevenson J. (The Ottawa Hospital). Croatia: BaÄiÄ G.
- Stevic D.
- Stewart K. E.
- Stylianides N. (Manchester Royal Infirmary)
- Stylianidis G. (Evaggelismos General Hospital)
- Subhi M. T. (Alkhadra Hospital)
- Subocius A.
- Subramaniam S. (Queen Elizabeth Hospital and Universiti Malaysia Sabah
- Sundaram Venkatesan G. (Glan Clwyd Hospital)
- SusztĂĄk N. (Szent BorbĂĄla KĂłrhĂĄz). India: Bhat G. A.
- Sutherland A. (Coffs Harbour Health Campus)
- Swinson B. (Royal Brisbane and Womenâs Hospital). Austria: Messner F.
- Syed W. A. S.
- Syllaios A.
- Szatmary P.
- Szubota I. (Hospital and Oncological Centre Novy Jicin). Denmark: EbbehĂžj A. L.
- SĂĄnchez del Pueblo C.
- SĂĄnchez Fuentes N.
- SĂĄnchez- Pernaute A.
- SĂĄnchez- Rubio M.
- SĂĄnchez-GarcĂa S.
- Taddei A.
- Tadic B.
- Taibi A. (Chu Limoges)
- Talal El-Abur I.
- Talwar R. (Luton and Dunstable University Hospital)
- Tammaro P.
- Tan J. A.
- Tan X. S.
- Tanal M.
- Tang A. M.
- Tanzanu M.
- Tartaglia D. (Azienda Ospedaliero Universitaria Pisana)
- Tasis N. (Athens Naval and Veterans Hospital)
- Tatar O. C.
- Tavares F.
- Tayeh S. (Homerton University Hospital)
- Tebala G. D.
- Teixeira J. (Centro Hospitalar UniversitĂĄrio do Algarve â Unidade de Faro)
- Teixeira M. (Centro Hospitalar do Tamega e Sousa)
- Tejero- Pintor F. J. (Hospital Universitario RĂo Hortega)
- Testa V. (Santa Croce E. Carle Hospital
- Tewari N. (University Hospitals Coventry and Warwickshire NHS Trusts)
- Tezas S. (Furness General Hospital)
- Thaha M.
- Thanapal M. R. (Hospital Kuala Lumpur)
- Theodosopoulos T.
- Theophilidou E. (Royal Derby Hospital)
- Thian A.
- Thomas A. (Royal Liverpool University Hospital)
- Thompson D. (Morriston Hospital Swansea)
- Thornhill M. (Dell Seton Medical Center at the University of Texas)
- Thrumurthy S. (Epsom and St Helier University Hospitals NHS Trust)
- Thulasiraman S. V.
- Timbrell S.
- Tirloni L.
- Titu S. (Prof. Dr. Ion Chiricuta Institute of Oncology). Russia: Garmanova T.
- Tonini V. (S. Orsola-Malpighi Hospital)
- Torres A. (Hospital ClĂnico de Madrid)
- Torres Arcos C.
- Townson A.
- Trabulsi N. (King Abdulaziz University Hospital)
- Travaglio E. (Regina Montis Regalis Hospital
- Tribillon E. (Institut Mutualiste Montsouris)
- Troncoso Pereira P. (Hospital Mateu Orfila)
- Tropeano F. P. (Federico II University Hospital)
- Trujillo DĂaz J.
- Tsai L.
- Tsarkov P.
- Tsiamalou I.
- Tsiaoussis I.
- TU Dresden)
- Tucci R. (Azienda Ospedaliera Universitaria Careggi)
- Tufo A. (Ospedale del Mare)
- Tugmen C.
- Tulina I. (Clinic of Coloproctology and Minimally Invasive Surgery
- Tuncer K.
- Turnbull A. (Victoria Hospital Kirkcaldy)
- Turrado-Rodriguez V.
- Turri G. (Azienda Ospedaliera Universitaria Integrata di Verona)
- Tweedle E. (Addenbrookeâs Hospital)
- Ugarte-Sierra B. (Hospital Universitario de Galdakao)
- UludaÄ S. S.
- Umair M.
- Universiti Sains Malaysia)
- University of Amsterdam)
- UniversitĂ di Ferrara)
- Université Mohammed V Rabat). Netherlands: Hompes R.
- Uras C. (Acibadem Maslak Hospital)
- Urbani A. (Azienda Ospedaliero Universitaria Sanâanna)
- Urbieta A. (Hospital Universitario la Paz)
- Uslu G.
- Utkan N. Z.
- Uyanik M. S. (Samsun Training and Research Hospital)
- Uzunoglu F. G. (University Medical Center HamburgâEppendorf). Greece: Antonakis P.
- Vaccarella G. (Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello)
- Valbuena Jabares V. (Marqués de Valdecilla University Hospital)
- Valdes- Hernandez J. (Hospital Universitario Virgen Macarena)
- Valero Soriano M. (Hospital General Reina SofĂa)
- Valle Rubio A. (Getafe University Hospital)
- Valverde S. (Hospital Clinic Barcelona)
- Van den Eynde J.
- Van den Eynde R. (Uz Leuven). Bulgaria: Sokolov M. (University Hospital Alexandrovska). Canada: Boutros M.
- Varma M. (University of California
- VasljeviÄ J.
- Vassiliu P. (Attikon University General Hospital)
- Vaz Pereira R.
- Vaz S. (Centro Hospitalar e UniversitĂĄrio de SĂŁo JoĂŁo)
- Velchuru V.
- Velickovic D. (Clinic for Digestive Surgery
- Velidedeoglu M.
- Venn M. (Royal London Hospital)
- Venskutonis D. (Lithuanian University of Health Sciences Kaunas Clinical Hospital). Madagascar: Rasoaherinomenjanahary F.
- Vera Mansilla C. (Hospital Universitario Principe de Asturias)
- Verberne C. (John Radcliffe Hospital)
- Vergari R. (Ospedali Riuniti di Ancona)
- Vernon L. (Cork University Hospital)
- Vervoort D.
- Vescio G. (University âMagna Graeciaâ of Catanzaro)
- Vezakis A. (Aretaieion Hospital)
- Videira J. F. (IPO Porto). RĂ©union: Kassir R.
- Vieira B. (Centro Hospitalar de TrĂĄs-Os-Montes e Alto Douro
- Vieira Caroço T. (IPO Coimbra)
- Vieira Paiva Lopes A. C. (Hospital de Torres Vedras â Centro Hospitalar do Oeste)
- Vignali A. (San Raffaele Scientific Institute
- Vigorita V. (Ălvaro Cunqueiro Hospital)
- Vijayan D. (Queen Elizabeth Hospital Birmingham)
- Villalabeitia Ateca I. (Hospital Universitario Cruces)
- Vimalachandran D. (Countess of Chester Hospital)
- Viswanath Y. K. S. (James Cook University Hospital)
- Vitali A. (Ospedale San Giovanni di Dio)
- Vitone L. (Royal Blackburn Hospital)
- Vives R. V. (Bellvitge University Hospital)
- Vo U. G. (Fiona Stanley Hospital)
- Von Papen M.
- Vovola F. (Ospedali Riuniti Azienda Ospedaliera Universitaria Foggia)
- Vucic N.
- VĂĄzquez FernĂĄndez A. (Hospital ClĂnico Universitario de Valladolid)
- Wadham B. (The University Hospital of South Manchester)
- Walkes K. (Queen Elizabeth Hospital). Belgium: Flamey N.
- Wani R. (Sher-I-Kashmir Institute of Medical Sciences)
- Waqar S. H. (Pakistan Institute of Medical Sciences). Poland: Major P. (Jagiellonian University Medical College). Portugal: Azevedo C.
- Warren O. (Chelsea and Westminster Hospital)
- Watson L. J. (Sunderland Royal Hospital)
- Watson N. (Kingâs Mill Hospital)
- Weitz J.
- Welsch T. (Carl-Gustav-Carus University Hospital
- Werner J. (LMU Klinikum Campus Innenstadt)
- Westwood E. (James Paget University NHS Foundation Trust Hospital)
- Whelan M. (Tallaght University Hospital)
- Whitmore H. (Torbay and South Devon NHS Trust)
- Wilkin R. J. W. (South Warwickshire NHS Foundation Trust)
- Wilkins A. (Hull University Teaching Hospitals NHS Trust)
- Williams G. (Royal Gwent Hospital)
- Williams K. (St Georgeâs Hospital)
- Wilson M. (Forth Valley Royal Hospital)
- Wimmer A. (Paracelsus Medical University Salzburg). Barbados: Barker D.
- Wong M.
- Worku D. (Queens Medical Centre)
- Wullschleger M. (Gold Coast University Hospital)
- Xavier R. G.
- Xenaki S.
- Xynos E. (University Hospital of Heraklion Crete and Interclinic Hospital of Crete). Hong Kong: Futaba K.
- Yang W.
- Yassin N. (Royal Wolverhampton NHS Trust)
- Ye G.
- Yesantharao P.
- Yetkin S. G. (Sisli Hamidiye Etfal Training and Research Hospital)
- YeĆilyurt D. (University of Health Sciences Tepecik Training and Research Hospital)
- Yiallourou A. (Nicosia General Hospital). Czechia: Martinek L.
- Yıldırım A.
- Yildiz A. (Yildirim Beyazit University Yenimahalle Training and Research Hospital). Uganda: Lule H.
- Young R. (York Teaching Hospitals NHS Trust)
- Yousof E. A. (Assiut University Hospital)
- Youssef M. (Norfolk and Norwich University Hospital)
- Yurttas C. (University Hospital Tuebingen)
- YĂĄnez C. (Royo Villanova)
- YĂŒksel E. (Kocaeli University Teaching Hospital)
- Zafar S. N. (University of Wisconsin)
- Zakaria A. D.
- Zakaria Z. (School of Medical Sciences and Hospital
- Zambon M. (Policlinico Umberto I Sapienza University of Rome)
- Zanus G. (Caâ Foncello Treviso â DISCOG â UniversitĂ di Padova)
- Zegarac M. (Institute for Oncology and Radiology of Serbia)
- ZeliÄ M. (University Hospital Center Rijeka)
- Zengin A. K. (Istanbul Universty â CerrahpaĆa Medical Faculty)
- Zerbib P. (CHU Lille)
- Zervas K.
- Zese M. (Santa Maria degli Angeli Hospital ULSS 5 â Adria)
- Zhang H. (Concord Repatriation General Hospital)
- Zizzo M. (Azienda UnitĂ Sanitaria Locale â IRCCS di Reggio Emilia)
- Zografos C. (Laiko University Hospital)
- Zorrilla OrtĂșzar J. (Hospital General Universitario Gregorio Marañón)
- Zourntou S. (General Hospital of Larissa âKoutlimpaneio and Triantafylleioâ)
- Zubaidi A. M. (King Saud University). Serbia: AleksiÄ L.
- Ăngelo M.
- Ăelebi F.
- Ăolak E.
- Ăfner D. (Medical University of Innsbruck)
- Ăhlberger L.
- Ăzçelık M. F.
- ĂÄĂŒcĂŒ H.
- ĂberrĂŒck L.
- Äoza I.
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2020
- Field of study
This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic
- âŠ