249 research outputs found
Gauge dependence of effective action and renormalization group functions in effective gauge theories
The Caswell-Wilczek analysis on the gauge dependence of the effective action
and the renormalization group functions in Yang-Mills theories is generalized
to generic, possibly power counting non renormalizable gauge theories. It is
shown that the physical coupling constants of the classical theory can be
redefined by gauge parameter dependent contributions of higher orders in
in such a way that the effective action depends trivially on the gauge
parameters, while suitably defined physical beta functions do not depend on
those parameters.Comment: 13 pages Latex file, additional comments in section
Electron recombination with multicharged ions via chaotic many-electron states
We show that a dense spectrum of chaotic multiply-excited eigenstates can
play a major role in collision processes involving many-electron multicharged
ions. A statistical theory based on chaotic properties of the eigenstates
enables one to obtain relevant energy-averaged cross sections in terms of sums
over single-electron orbitals. Our calculation of the low-energy electron
recombination of Au shows that the resonant process is 200 times more
intense than direct radiative recombination, which explains the recent
experimental results of Hoffknecht {\em et al.} [J. Phys. B {\bf 31}, 2415
(1998)].Comment: 9 pages, including 1 figure, REVTe
Collectivity Embedded in Complex Spectra of Finite Interacting Fermi Systems: Nuclear Example
The mechanism of collectivity coexisting with chaos in a finite system of
strongly interacting fermions is investigated. The complex spectra are
represented in the basis of two-particle two-hole states describing the nuclear
double-charge exchange modes in Ca. An example of
excitations shows that the residual interaction, which generically implies
chaotic behavior, under certain specific and well identified conditions may
create strong transitions, even much stronger than those corresponding to a
pure mean-field picture. Such an effect results from correlations among the
off-diagonal matrix elements, is connected with locally reduced density of
states and a local minimum in the information entropy.Comment: 16 pages, LaTeX2e, REVTeX, 8 PostScript figures, to appear in
Physical Review
The Spin-Dependent Structure Functions of Nuclei in the Meson-Nucleon Theory
A theoretical approach to the investigation of spin-dependent structure
functions in deep inelastic scattering of polarized leptons off polarized
nuclei, based on the effective meson-nucleon theory and operator product
expansion method, is proposed and applied to deuteron and . The explicit
forms of the moments of the deuteron and spin-dependent structure
functions are found and numerical estimates of the influence of nuclear
structure effects are presented.Comment: 42 pages revtex, 7 postscript figures available from above e-mail
upon request. Perugia preprint DFUPG 92/9
Charge order and low frequency spin dynamics in lanthanum cuprates revealed by Nuclear Magnetic Resonance
We report detailed 17O, 139La, and 63Cu Nuclear Magnetic Resonance (NMR) and
Nuclear Quadrupole Resonance (NQR) measurements in a stripe ordered
La1.875Ba0.125CuO4 single crystal and in oriented powder samples of
La1.8-xEu0.2SrxCuO4. We observe a partial wipeout of the 17O NMR intensity and
a simultaneous drop of the 17O electric field gradient (EFG) at low
temperatures where the spin stripe order sets in. In contrast, the 63Cu
intensity is completely wiped out at the same temperature. The drop of the 17O
quadrupole frequency is compatible with a charge stripe order. The 17O spin
lattice relaxation rate shows a peak similar to that of the 139La, which is of
magnetic origin. This peak is doping dependent and is maximal at x ~ 1/8.Comment: submitted to European Physical Journal Special Topic
Association of a marker of N-acetylglucosamine with progressive multiple sclerosis and neurodegeneration
IMPORTANCE: N-glycan branching modulates cell surface receptor availability, and its deficiency in mice promotes inflammatory demyelination, reduced myelination, and neurodegeneration. N-acetylglucosamine (GlcNAc) is a rate-limiting substrate for N-glycan branching, but, to our knowledge, endogenous serum levels in patients with multiple sclerosis (MS) are unknown. OBJECTIVE: To investigate a marker of endogenous serum GlcNAc levels in patients with MS. DESIGN, SETTING, AND PARTICIPANTS: A cross-sectional discovery study and cross-sectional confirmatory study were conducted at 2 academic MS centers in the US and Germany. The discovery study recruited 54 patients with MS from an outpatient clinic as well as 66 healthy controls between April 20, 2010, and June 21, 2013. The confirmatory study recruited 180 patients with MS from screening visits at an academic MS study center between April 9, 2007, and February 29, 2016. Serum samples were analyzed from December 2, 2013, to March 2, 2015. Statistical analysis was performed from February 23, 2020, to March 18, 2021. MAIN OUTCOMES AND MEASURES: Serum levels of GlcNAc plus its stereoisomers, termed N-acetylhexosamine (HexNAc), were assessed using targeted tandem mass spectroscopy. Secondary outcomes (confirmatory study) comprised imaging and clinical disease markers. RESULTS: The discovery cohort included 66 healthy controls (38 women; mean [SD] age, 42 [20] years), 33 patients with relapsing-remitting MS (RRMS; 25 women; mean [SD] age, 50 [11] years), and 21 patients with progressive MS (PMS; 14 women; mean [SD] age, 55 [7] years). The confirmatory cohort included 125 patients with RRMS (83 women; mean [SD] age, 40 [9] years) and 55 patients with PMS (22 women; mean [SD] age, 49 [80] years). In the discovery cohort, the mean (SD) serum level of GlcNAc plus its stereoisomers (HexNAc) was 710 (174) nM in healthy controls and marginally reduced in patients with RRMS (mean [SD] level, 682 [173] nM; P = .04), whereas patients with PMS displayed markedly reduced levels compared with healthy controls (mean [SD] level, 548 [101] nM; P = 9.55 × 10(-9)) and patients with RRMS (P = 1.83 × 10(-4)). The difference between patients with RRMS (mean [SD] level, 709 [193] nM) and those with PMS (mean [SD] level, 405 [161] nM; P = 7.6 × 10(-18)) was confirmed in the independent confirmatory cohort. Lower HexNAc serum levels correlated with worse expanded disability status scale scores (ρ = -0.485; P = 4.73 × 10(-12)), lower thalamic volume (t = 1.7; P = .04), and thinner retinal nerve fiber layer (B = 0.012 [SE = 7.5 × 10(-11)]; P = .008). Low baseline serum HexNAc levels correlated with a greater percentage of brain volume loss at 18 months (t = 1.8; P = .04). CONCLUSIONS AND RELEVANCE: This study suggests that deficiency of GlcNAc plus its stereoisomers (HexNAc) may be a biomarker for PMS. Previous preclinical, human genetic, and ex vivo human mechanistic studies revealed that N-glycan branching and/or GlcNAc may reduce proinflammatory responses, promote myelin repair, and decrease neurodegeneration. Combined, the data suggest that GlcNAc deficiency may be associated with progressive disease and neurodegeneration in patients with MS
Shrinking a large dataset to identify variables associated with increased risk of Plasmodium falciparum infection in Western Kenya
Large datasets are often not amenable to analysis using traditional single-step approaches. Here, our general objective was to apply imputation techniques, principal component analysis (PCA), elastic net and generalized linear models to a large dataset in a systematic approach to extract the most meaningful predictors for a health outcome. We extracted predictors for Plasmodium falciparum infection, from a large covariate dataset while facing limited numbers of observations, using data from the People, Animals, and their Zoonoses (PAZ) project to demonstrate these techniques: data collected from 415 homesteads in western Kenya, contained over 1500 variables that describe the health, environment, and social factors of the humans, livestock, and the homesteads in which they reside. The wide, sparse dataset was simplified to 42 predictors of P. falciparum malaria infection and wealth rankings were produced for all homesteads. The 42 predictors make biological sense and are supported by previous studies. This systematic data-mining approach we used would make many large datasets more manageable and informative for decision-making processes and health policy prioritization
Measurement of W Polarisation at LEP
The three different helicity states of W bosons produced in the reaction e+
e- -> W+ W- -> l nu q q~ at LEP are studied using leptonic and hadronic W
decays. Data at centre-of-mass energies \sqrt s = 183-209 GeV are used to
measure the polarisation of W bosons, and its dependence on the W boson
production angle. The fraction of longitudinally polarised W bosons is measured
to be 0.218 \pm 0.027 \pm 0.016 where the first uncertainty is statistical and
the second systematic, in agreement with the Standard Model expectation
Search for Anomalous Couplings in the Higgs Sector at LEP
Anomalous couplings of the Higgs boson are searched for through the processes
e^+ e^- -> H gamma, e^+ e^- -> e^+ e^- H and e^+ e^- -> HZ. The mass range 70
GeV < m_H < 190 GeV is explored using 602 pb^-1 of integrated luminosity
collected with the L3 detector at LEP at centre-of-mass energies
sqrt(s)=189-209 GeV. The Higgs decay channels H -> ffbar, H -> gamma gamma, H
-> Z\gamma and H -> WW^(*) are considered and no evidence is found for
anomalous Higgs production or decay. Limits on the anomalous couplings d, db,
Delta(g1z), Delta(kappa_gamma) and xi^2 are derived as well as limits on the H
-> gamma gamma and H -> Z gamma decay rates
Measurement of W Polarisation at LEP
The three different helicity states of W bosons produced in the reaction e+
e- -> W+ W- -> l nu q q~ at LEP are studied using leptonic and hadronic W
decays. Data at centre-of-mass energies \sqrt s = 183-209 GeV are used to
measure the polarisation of W bosons, and its dependence on the W boson
production angle. The fraction of longitudinally polarised W bosons is measured
to be 0.218 \pm 0.027 \pm 0.016 where the first uncertainty is statistical and
the second systematic, in agreement with the Standard Model expectation
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