88 research outputs found

    Electronically Tunable Phase Response for Phased array Patches

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    The design and prototyping of radiating elements with tunable phase response, for reconfigurable patch array antennas, is presented. Different options are found in the technical literature to obtain feasible reconfigurable array antennas: placing the active circuitry in the transmission lines or directly over the radiating element, obtaining the desired phase shift for each radiating element of the array. In this reported work, the second option is selected and active radiating elements at 12 GHz are designed and prototyped

    Phase-space resolved measurement of 2nd harmonic ion cyclotron heating using FIDA tomography at the ASDEX Upgrade tokamak:Paper

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    Recent upgrades to the FIDA (fast-ion D-alpha) diagnostic at ASDEX Upgrade allow to reconstruct the fast-ion phase space at several radial positions with decent energy and pitch resolution. These new diagnostic capabilities are applied to study the physics of 2nd harmonic ion cyclotron heating, which is a foreseen heating scenario for ITER. In particular, the acceleration of deuterium beam ions above the injection energy by absorption of ion cyclotron waves at the 2nd harmonic is investigated and compared to theoretical predictions by the TORIC-SSFPQL and TORIC-NUBEAM code packages. Furthermore, comparisons to other fast-ion diagnostics (neutron yield and neutral particle analyzers) are discussed.EUROfusion Consortium 63305

    Effective Phone Calls

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    “Effective Phone Calls” is a practical and accessible course specifically designed to develop students` essential communication and language skills. It is divided into six units, which contain face-to-face with teacher and self-study materials. The course aims to develop both competence and confi-dence in a variety of situations, so that by the end of the period of study students will have acquired the necessary skills to handle almost any kind of call in business setting

    Implementation of an End-to-End Standards-based Patient Monitoring Solution

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    A proof-of-concept design of a patient monitoring solution for intensive care unit environments has been presented. It is end-to-end standard-based, using ISO/IEEE 11073 (X73) in the bedside environment and EN13606 to communicate the information to an electronic healthcare record (EHR) server. At the bedside end, the system is a plug-and-play sensor network communicating with a gateway that collects medical information and sends the data to a monitoring server. The monitoring server transforms this information into an EN13606 extract to be stored on the EHR server. The system has been implemented to comply with the last X73 and EN13606 available versions and tested in a laboratory environment to demonstrate the feasibility of an end-to-end standard-based solution

    A hot mini-Neptune and a temperate, highly eccentric sub-Saturn around the bright K-dwarf TOI-2134

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    Funding: ACC and TGW acknowledge support from STFC consolidated grant numbers ST/R000824/1 and ST/V000861/1, and UKSA grant number ST/R003203/1. RDH is funded by the UK Science and Technology Facilities Council (STFC)’s Ernest Rutherford Fellowship (grant no. ST/V004735/1). SD is funded by the UK Science and Technology Facilities Council (grant no. ST/V004735/1). BSL is funded by a UK Science and Technology Facilities Council (STFC) studentship (ST/V506679/1). This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement SCORE no. 851555).We present the characterisation of an inner mini-Neptune in a 9.2292005±0.0000063 day orbit and an outer mono-transiting sub-Saturn planet in a 95.50+0.36-0.25 day orbit around the moderately active, bright (mv = 8.9 mag) K5V star TOI-2134. Based on our analysis of five sectors of TESS data, we determine the radii of TOI-2134b and c to be 2.69±0.16 R⊕ for the inner planet and 7.27±0.42 R⊕ for the outer one. We acquired 111 radial-velocity spectra with HARPS-N and 108 radial-velocity spectra with SOPHIE. After careful periodogram analysis, we derive masses for both planets via Gaussian Process regression: 9.13+0.78-0.76 M⊕ for TOI-2134b and 41.89+7.69-7.83 M⊕ for TOI-2134c. We analysed the photometric and radial-velocity data first separately, then jointly. The inner planet is a mini-Neptune with density consistent with either a water-world or a rocky core planet with a low-mass H/He envelope. The outer planet has a bulk density similar to Saturn’s. The outer planet is derived to have a significant eccentricity of 0.67+0.05-0.06 from a combination of photometry and RVs. We compute the irradiation of TOI-2134c as 1.45±0.10 times the bolometric flux received by Earth, positioning it for part of its orbit in the habitable zone of its system. We recommend further RV observations to fully constrain the orbit of TOI-2134c. With an expected Rossiter-McLaughlin (RM) effect amplitude of 7.2±1.3 m-1, we recommend TOI-2134c for follow-up RM analysis to study the spin-orbit architecture of the system. We calculate the Transmission Spectroscopy Metric, and both planets are suitable for bright-mode NIRCam atmospheric characterisation.Publisher PDFPeer reviewe

    Multiwavelength study of quiescent states of MRK 421 with unprecedented hard x-ray coverage provided by<i> NuSTAR</i> in 2013

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    Coherent psi (2S) photo-production in ultra-peripheral Pb-Pb collisions at root s(NN)=2.76TeV

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    We have performed the first measurement of the coherent psi(2S) photo-production cross section in ultraperipheral Pb-Pb collisions at the LHC. This charmonium excited state is reconstructed via the psi(2S) -> l(+)l(-) and ->(2S) -> J/psi pi(+)pi(-) decays, where the J/psi decays into two leptons. The analysis is based on an event sample corresponding to an integrated luminosity of about 22 mu b(-1). The cross section for coherent psi(2S) production in the rapidity interval -0.9 <y <0.9is d sigma(coh)(psi(2S))/dy = 0.83 +/- 0.19 (stat+syst) mb. The psi(2S) to J/psi coherent cross section ratio is 0.34(-0.07)(+0.08)(stat+syst). The obtained results are compared to predictions from theoretical models. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V.Peer reviewe

    Energy dependence of ϕ meson production at forward rapidity in pp collisions at the LHC

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    The production of ϕ\phi mesons has been studied in pp collisions at LHC energies with the ALICE detector via the dimuon decay channel in the rapidity region 2.5<y<42.5< y < 4. Measurements of the differential cross section d2σ/dydpT\mathrm{d}^2\sigma /\mathrm{d}y \mathrm{d}p_{\mathrm {T}} are presented as a function of the transverse momentum (pTp_{\mathrm {T}}) at the center-of-mass energies s=5.02\sqrt{s}=5.02, 8 and 13 TeV and compared with the ALICE results at midrapidity. The differential cross sections at s=5.02\sqrt{s}=5.02 and 13 TeV are also studied in several rapidity intervals as a function of pTp_{\mathrm {T}}, and as a function of rapidity in three pTp_{\mathrm {T}} intervals. A hardening of the pTp_{\mathrm {T}}-differential cross section with the collision energy is observed, while, for a given energy, pTp_{\mathrm {T}} spectra soften with increasing rapidity and, conversely, rapidity distributions get slightly narrower at increasing pTp_{\mathrm {T}}. The new results, complementing the published measurements at s=2.76\sqrt{s}=2.76 and 7 TeV, allow one to establish the energy dependence of ϕ\phi meson production and to compare the measured cross sections with phenomenological models. None of the considered models manages to describe the evolution of the cross section with pTp_{\mathrm {T}} and rapidity at all the energies.publishedVersio

    ϒ production in p–Pb collisions at sNN=8.16 TeV

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    ϒproduction in p–Pbinteractions is studied at the centre-of-mass energy per nucleon–nucleon collision √sNN=8.16TeV with the ALICE detector at the CERN LHC. The measurement is performed reconstructing bottomonium resonances via their dimuon decay channel, in the centre-of-mass rapidity intervals 2.03 &lt;3.53and −4.46 &lt;−2.96, down to zero transverse momentum. In this work, results on the ϒ(1S) production cross section as a function of rapidity and transverse momentum are presented. The corresponding nuclear modification factor shows a suppression of the ϒ(1S) yields with respect to ppcollisions, both at forward and backward rapidity. This suppression is stronger in the low transverse momentum region and shows no significant dependence on the centrality of the interactions. Furthermore, the ϒ(2S) nuclear modification factor is evaluated, suggesting a suppression similar to that of the ϒ(1S). A first measurement of the ϒ(3S) has also been performed. Finally, results are compared with previous ALICE measurements in p–Pbcollisions at √sNN=5.02TeV and with theoretical calculations

    Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

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    In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. For example, a key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process versus those that measure fl ux through the autophagy pathway (i.e., the complete process including the amount and rate of cargo sequestered and degraded). In particular, a block in macroautophagy that results in autophagosome accumulation must be differentiated from stimuli that increase autophagic activity, defi ned as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (inmost higher eukaryotes and some protists such as Dictyostelium ) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the fi eld understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. It is worth emphasizing here that lysosomal digestion is a stage of autophagy and evaluating its competence is a crucial part of the evaluation of autophagic flux, or complete autophagy. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. Along these lines, because of the potential for pleiotropic effects due to blocking autophagy through genetic manipulation it is imperative to delete or knock down more than one autophagy-related gene. In addition, some individual Atg proteins, or groups of proteins, are involved in other cellular pathways so not all Atg proteins can be used as a specific marker for an autophagic process. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field
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