44 research outputs found
Fabrication and Characterization of Gliclazide Loaded Microcapsules
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Serosurvey for Leishmania spp., Toxoplasma gondii, Trypanosoma cruzi and Neospora caninum in neighborhood dogs in Curitiba-Paraná, Brazil
- Author
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Scaffolds for cartilage regeneration: to use or not to use?
- Author
- A Akkouch
- A Hazwani
- A Martín-Martín
- A Ovsianikov
- A Roffi
- AH Tahir
- C De Pascale
- D He
- D Izzo
- D Shier
- DC Kelly
- E Tetsuya
- EK Breathwaite
- F Yusof
- FH Martini
- GJ Tortora
- H Lin
- H Rogan
- H Takahashi
- I Catacchio
- IN Aguilar
- IS Park
- J Antunes
- J Kobayashi
- J Li
- J Li
- JM Baena
- K Chen
- K Wang
- K Xue
- KE Benders
- KS Saladin
- L De Moor
- LT Kuhn
- M Ahmad
- M Farokhi
- M Farokhi
- M Myohara
- M Yamato
- MAI Mohamed Amin
- Malaysia health technology assessment section (MaHTAS)
- Malaysia Health Technology Assessment Section (MaHTAS)
- N Md Nazir
- NM Nazir
- PS Wiggenhauser
- R Ahmad
- R Muriel
- S Munirah
- S Munirah
- SL Francis
- V Theo
- VP Sivadas
- W Chen
- Y Lu
- Y Yu
- YC Angela
- YT Wen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
Joint cartilage has been a significant focus on the field of tissue engineering and regenerative medicine (TERM) since its inception in the 1980s. Represented by only one cell type, cartilage has been a simple tissue that is thought to be straightforward to deal with. After three decades, engineering cartilage has proven to be anything but easy. With the demographic shift in the distribution of world population towards ageing, it is expected that there is a growing need for more effective options for joint restoration and repair. Despite the increasing understanding of the factors governing cartilage development, there is still a lot to do to bridge the gap from bench to bedside. Dedicated methods to regenerate reliable articular cartilage that would be equivalent to the original tissue are still lacking. The use of cells, scaffolds and signalling factors has always been central to the TERM. However, without denying the importance of cells and signalling factors, the question posed in this chapter is whether the answer would come from the methods to use or not to use scaffold for cartilage TERM. This paper presents some efforts in TERM area and proposes a solution that will transpire from the ongoing attempts to understand certain aspects of cartilage development, degeneration and regeneration. While an ideal formulation for cartilage regeneration has yet to be resolved, it is felt that scaffold is still needed for cartilage TERM for years to come
Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.
- Author
- Aamir A
- Abbas J
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- Abbott TEF
- Abdalla M
- Abdikadir H
- Abuhussein N
- Acquaah F
- Adamson R
- Adeleye O
- Adeogun A
- Adlan A
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- Afzal Z
- Agarwal M
- Aglan H
- Agnew CJF
- Agrawal R
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- Ahluwalia J
- Ahluwalia V
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- Paraskeva B
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- Paterson HM
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- Poolovadoo Y
- Poonawala R
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- Powell B
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- Preece R
- Premakumar Y
- Price M
- Printz V
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- Prowle J
- Prudence-Taylor AJ
- Puddy H
- Pullinger M
- Punjabi N
- Pursnani K
- Qadeer A
- Qamar I
- Qamar MA
- Quek R
- Qureshi A
- Rabiu R
- Radford A
- Radhakrishnan A
- Radotra A
- Rafferty C
- Rafiq NM
- Raghuvir V
- Rahunathan N
- Rai A
- Raja M
- Rajagopal R
- Rajendran S
- Ramakrishnan D
- Ramanujam N
- Ramjas D
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- Ramsden J
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- Rana S
- Randhawa R
- Rangarajan S
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- Rea E
- Redgrave N
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- Renju M
- Renukanthan A
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- Reynolds J
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- Richards T
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- Ridgway P
- Riley BJ
- Rimmer L
- Rinkoff S
- Riyat H
- Roberts B
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- Robinson SD
- Rockall T
- Rodman L
- Roe T
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- Roscoe HW
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- Saat MI
- Sadanand KS
- Sadhra SS
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- Saeed F
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- Sait S
- Saito R
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- Samaraweera S
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- Sandhu A
- Sandhu J
- Sandhu N
- Sandland-Taylor L
- Sangal P
- Sansome S
- Sarathy PP
- Saravanabavan S
- Sardar M
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- Sathiyakeerthy A
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- Sattar Z
- Saunders I
- Saunders M
- Sawers N
- Sawkins H
- Schade A
- Schinle P
- Schramm M
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- Scott K
- Scott M
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- Seehra J
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- Seetharam P
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- Sen P
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- Serry M
- Seth I
- Sethi R
- Shafi A
- Shafiq N
- Shaid M
- Shaman S
- Shang E
- Sharif I
- Sharkey E
- Sharma A
- Sharma E
- Sharma S
- Shaw A
- Shaw C
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- Sheikh A
- Sheikh S
- Sheikh Z
- Shergill M
- Shergill S
- Sherlock J
- Shields P
- Shingles C
- Shirazi S
- Shurovi BN
- Siddiqui A
- Siddiqui I
- Silke E
- Sim DPY
- Sim R
- Simmonds L
- Simon A
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- Singagireson S
- Singh K
- Singh KKR
- Sinha C
- Sivagnanasithiyar T
- Sivakumar C
- Sivakumar R
- Skulsky S
- Slade G
- Slade RD
- Sleight S
- Small S
- Smallwood J
- Smart B
- Smart G
- Smart YW
- Smith ACD
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- Springford LR
- Srikanthan M
- Sriram A
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- Stanger S
- Stanier P
- STARSurg Collaborative Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators
- STARSurg Collaborative Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators, Nepogodiev, D
- Stechman M
- Stewart D
- Stewart E
- Stewart H
- Stewart R
- Stickler E
- Stoddart MT
- Stokes E
- Stott G
- Strang S
- Stringer H
- Stringfellow TD
- Stubbing-Moore A
- Sturrock S
- Subar D
- Subratty SM
- Sukirthan N
- Sukumar S
- Sulaiman SK
- Sultan S
- Sun L
- Sundaram K
- Suresh R
- Suresh S
- Sureshkumar A
- Suri A
- Svolkinas D
- Swan A
- Swan I
- Swaray A
- Swartbol T
- Symons L
- Szczap A
- Szuman A
- Tailor S
- Tam J
- Tam JP
- Tan CY
- Tan KL
- Tan L
- Tan LC
- Tan S
- Tan TSE
- Tang A
- Tang M
- Tanna A
- Taribagil P
- Tariq A
- Tate S
- Tayeh S
- Taylor K
- Taylor O
- Taylor R
- Taylor Z
- Telfer R
- Teng T
- Tenters F
- Teo R
- Thachettu A
- Thakrar D
- Thatcher A
- Theodoropoulou K
- Thomas A
- Thomas D
- Thomas M
- Thomas O
- Thomas S
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- Thompson J
- Thoms BL
- Thomson F
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- Tilliridou V
- Titu L
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- Toellner H
- Toh C
- Toma T
- Tonks A
- Torrance HD
- Townsend D
- Traish M
- Trenear R
- Tresidder S
- Trevett J
- Triniman MC
- Trotter M
- Tsang JCH
- Tsang K
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- Turner J
- Turner S
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- Vadgama N
- Vaidya A
- Vakharia A
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- Van der Laan S
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- Ventre C
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- Wadood Q
- Waite K
- Wakeford W
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- Warusavitarne J
- Waterman A
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- Whitcroft I
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- Whitham R
- Whyte M
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- Worsfold M
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- Wynell-Mayow W
- Xu Y
- Yahaya AA
- Yalamarthi S
- Yang DD
- Yang N
- Yap J
- Yardimci E
- Yarham E
- Yasin IH
- Yasin T
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- Yeo A
- Yeoh T
- Yeung J
- Yin ZD
- Yip J
- Yoganayagam N
- Yogeswara T
- York J
- Yousaf A
- Youssef H
- Yu T
- Yule A
- Zaat S
- Zanichelli D
- Zaver V
- Zeng R
- Zhang Y
- Zheleniakova T
- Zhu Y
- Zornoza A
- Zubikarai G
- Zulkifli A
- Zuzarte L
- Publication venue
- 'Wiley'
- Publication date
- 18/05/2018
- Field of study
Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14·2 per cent (646 of 4544) and the 30-day mortality rate was 1·8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7·61, 95 per cent c.i. 4·49 to 12·90; P < 0·001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0·65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability
Feasibility and reliability of frailty assessment in the critically ill: a systematic review
- Author
- A Clegg
- A Clegg
- A Rodriguez-Molinero
- AM Ahasic
- Amy Ellison
- Andrew Clegg
- BJ Buta
- C Fisher
- C Oczkowski
- Chris M. Thorpe
- Christian P. Subbe
- D Heyland
- D Moher
- DB Hogan
- DC Scales
- DF Stroup
- DK Heyland
- DM Jones
- E Dent
- FJ Carod-Artal
- GC Ihra
- H Flaatten
- J Apostolo
- J Muscedere
- JL Sutton
- K Rockwood
- Kate Pye
- LB Mokkink
- LP Fried
- M Bagshaw
- M Li
- MR Baldwin
- Nazir I. Lone
- NE Brummel
- NM Vries de
- O Theou
- P Maguet Le
- PJ Neumann
- RC McDermid
- Richard J. Pugh
- RJ Gobbens
- RJ Pugh
- SM Bagshaw
- SM Bagshaw
- SM Bagshaw
- SN Hilmer
- TJ Iwashyna
- VD Dinglas
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/02/2018
- Field of study
Background. For healthcare systems, an ageing population poses challenges in the delivery of equitable and effective care. Frailty assessment has the potential to improve care in the intensive care setting, but applying assessment tools in critical illness may be problematic. The aim of this systematic review was to evaluate evidence for the feasibility and reliability of frailty assessment in critical care. Methods. Our primary search was conducted in Medline, Medline In-process, EMBASE, CINAHL, PsycINFO, AMED, Cochrane Database of Systematic Reviews, and Web of Science (January 2001 to October 2017). We included observational studies reporting data on feasibility and reliability of frailty assessment in critical care setting in patients 16 years and older. Feasibility was assessed in terms of timing of evaluation, the background, training and expertise required for assessors, and reliance upon proxy input. Reliability was assessed in terms of inter-rater reliability. Results. Data from 11 study publications are included, representing eight study cohorts and 7761 patients. Proxy involvement in frailty assessment ranged from 58- 100%. Feasibility data were not well-reported overall, but the exclusion rate due to lack of proxy availability ranged from 0 to 45%, the highest rate observed where family involvement was mandatory and the assessment tool relatively complex (Frailty Index, FI). Conventional elements of Frailty Phenotype (FP) assessment required modification prior to use in two studies. Clinical staff tended to use a simple judgement-based tool, the Clinical Frailty Scale (CFS). Inter-rater reliability was reported in one study using the CFS and although a good level of agreement was observed between clinician assessments, this was a small and single centre study. Conclusion. Though of unproven reliability in the critically ill, CFS was the tool used most widely by critical care clinical staff. Conventional FP assessment required modification for general application in critical care, and a FI-based assessment may be difficult to deliver by the critical care team on a routine basis. There is a high reliance on proxies for frailty assessment, and the reliability of frailty assessment tools in critical care needs further evaluation. PROSPERO CRD42016052073
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
- Aahlin EK
- Aamer A
- Aaniana K
- Ababneh A
- Abaliksta T
- Abantanga F
- Abantanga F
- Abbas A
- Abbas M
- Abbasy J
- Abbo O
- Abbo O
- Abbott T
- Abbouch M
- Abd El Galeel A
- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
- Abdel-Aty A
- Abdel-Hameed N
- Abdel-Kader SM
- Abdel-Wahab NYE
- Abdelaal A
- Abdelaty M
- Abdelazeam AR
- Abdelazim G
- Abdelaziz MA
- Abdelbadeai K
- Abdelfatah A
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelhady S
- Abdelhamed R
- Abdelhamid A
- Abdelhaq A
- Abdelkader M
- Abdelkader M
- Abdelkader O
- Abdelkareem A
- Abdelkhalek M
- Abdelmageed E
- Abdelmotaleb I
- Abdelraheim M
- Abdelraouf AM
- Abdelrouf DM
- Abdelshafy M
- Abdelshakour M
- Abdrabou AK
- Abdul-Latif S
- Abdulaziz H
- Abdulaziz M
- Abdulbagi O
- Abdulgawad M
- Abdulhakeem EM
- Abdullah AAN
- Abdullah MA
- Abdullah N
- Abdullah NAN
- Abdullah NAN
- Abdullahi L
- Abdurrazzaaq A
- Abebe NS
- Abebe NS
- Abem OE
- Aber A
- Abington E
- Abiola O
- Aboarab A
- Aboelella M
- Aboelmagd O
- Aboelsoud MR
- Aboraya M
- Aboraya M
- Abouelnasr A
- Aboul-Naga MS
- Abouzahra A
- Abouzaid A
- Abozaid M
- Abozeid K
- Abozyed MAF
- Abu Qumbos A
- Abu-toyour M
- Abubakr M
- Abudeeb H
- Abuowda Y
- Abuqwaider E
- Abusalem L
- Abuseif M
- Abushamleh S
- Acharya P
- Ackom E
- Acquah E
- Adam A
- Adam N
- Adams R
- Adamu A
- Adawi I
- Adawi M
- Adebanjo A
- Adebanjo A
- Adebola O
- Adedeji A
- Adekoya A
- Adel A
- Adel A
- Adel BE
- Adel I
- Adella FJ
- Adelshone A
- Ademuyiwa A
- Ademuyiwa A
- Ademuyiwa AO
- Ademuyiwa AO
- Ademuyiwa AO
- Ademuyiwa AO
- Adenekan B
- Adeniran J
- Adeniran J
- Adeniyi A
- Adeniyi A
- Adesanya O
- Adesanya O
- Adesina A
- Adesina A
- Adesuyi A
- Adeyeye A
- Adeyeye A
- Adeyeye A
- Adham W
- Adhitama N
- Adil M
- Adisa AO
- Adisa AO
- Adu-Aryee N
- Afana S
- Afandy A
- Afifi AM
- Afzal M
- Agalianos C
- Agalianos C
- Agarwal A
- Agarwal A
- Agarwal A
- Agbedinu K
- Agius M
- Aglan A
- Aguado Suarez N
- Aguilar-Jimenez J
- Aguilera M
- Aguilera ML
- Aguilera ML
- Aguilera ML
- Aguilera O
- Aguilera-Arevalo M-L
- Ahlonsou G
- Ahlqvist S
- Ahlqvist S
- Ahlqvist S
- Ahmed A
- Ahmed A
- Ahmed A
- Ahmed EA
- Ahmed H
- Ahmed H
- Ahmed H
- Ahmed LAM
- Ahmed S
- Ahmed S
- Ahmed SM
- Ahounou EYS
- Aigrain Y
- Aiyaman C
- Ajah J
- Ajai O
- Ajao A
- Ajao AE
- Ajiboye A
- Akatibo E
- Akeel N
- Akhtar M
- Akoto E
- Akpenyi O
- Al Amin S
- Al Attar SM
- Al Awwad S
- Al Barrawi FE
- Al Bastawis F
- Al Meligy A
- Al Rafati AAR
- Al Raouf EA
- Al Saied G
- Al Subaie N
- Al-Aarag AA-R
- Al-Azraqi IAA
- Al-Bahrani A
- Al-Buhaisi A
- Al-Dakka E
- Al-Faifi JJ
- Al-faqawi M
- Al-farram H
- Al-Hameedi HII
- Al-Hasani RKMJ
- Al-khatib A
- Al-Mallah A
- Al-Marakby D
- Al-Mousa M
- Al-Nahrawi S
- Al-Obaedi O
- Al-saqqa S
- Al-Saqqa SW
- Al-Saqqa SW
- Al-shammari A
- Al-Slaibi I
- Al-taher T
- Alaael-Dein S
- Alada M
- Alahmady O
- Alakaloko F
- Alakaloko F
- Alaloul E
- Alamin S
- Alamoudi M
- Alamoudi U
- Albeladi B
- Albiety A
- Alcca Ticona W
- Aldalaq A
- Aldhafeeri S
- Aledrisy M
- Alejos Bermudez YE
- Alexander P
- Alexander P
- Alexander P
- Alexandre C
- Alfarsi MA
- Alghamdi A
- Alghamdi B
- Alghamdi M
- Alghamdi MSA
- Algohary O
- Alhabli I
- Alhady K
- Alhammali T
- Alhassan B
- Alhazmi W
- Alhendy M
- Alherz M
- Ali A
- Ali A
- Ali A
- Ali CDM
- Ali E
- Ali FM
- Ali H
- Ali S
- Ali SAWEW
- Ali SS
- Ali THA
- Ali W
- Alihonou T
- Alimi Q
- Alis H
- Aliyu H
- Aliyu M
- Aliyu S
- Aljboor K
- Aljiffry M
- Aljiffry M
- Aljohani E
- Aljohani E
- Aljohani S
- Alkaaki A
- Alkammash A
- Alkelani M
- Alkhabbaz D
- Alkhouri M
- Allam M
- Allam M
- Allam Y
- Allegri A
- Allegri A
- Allen JLY
- Allott R
- Almallah A
- Almoflihi A
- Almuallem S
- Almy J
- Alnaby MH
- Alnawam E
- Alnuqaydan SA
- Alnusairat A
- Alomar IN
- Alqahtani E
- Alqahtani S
- Alrahawy M
- Alrajraji M
- Alrifaie A
- AlRowais M
- Alsaggaf M
- Alsaggaf MU
- Alsaggaf MU
- Alser OH
- Alshareef R
- Altaf A
- Altaf A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamini A
- Altarayra M
- Althwainy A
- Altibi A
- Altinel Y
- Altinel Y
- Altoe F
- Altwigry AM
- Altwijri A
- Alvarado Jaramillo R
- Alvarez Barreda LM
- Alvi AR
- Alwafai MG
- Aly AK
- Aly MYM
- Alyacoubi S
- Alyahya R
- Alyami R
- Alyami R
- AlYoussef I
- Alzahrani A
- Alzahrani M
- Alzahrani M
- Alzayat T
- Aman NF
- Amandito R
- Amandito R
- Amandito R
- Amandito R
- Ambrona-Zafra D
- Ambrozeviciute V
- Ameen M
- Amer MA
- Amin HAA
- Amin J
- Amin J
- Amjad M
- Ammar M
- Ammar MS
- Amoah M
- Amoako J
- Amoako PT
- Amoako-Boateng M
- Amole I
- Amreia M
- Amreia M
- Anandkumar D
- Anderson D
- Anderson F
- Anderson R
- Anderson-Knight H
- Andersson L
- Andika FFA
- Andreotti D
- Andres Garcia-Marin J
- Andress C
- Andriola V
- Ang YL
- Angelieri D
- Anis E
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Antar S
- Antezana D
- Anthoulakis C
- Anthoulakis C
- Antoniozzi A
- Anwar AW
- Anwar N
- Anwer W
- Anyanwu L-J
- Anyanwu L-J
- Aonzo P
- Appeadu-Mensah W
- Appiah EK
- Aql S
- Aquilino F
- Arachchi PP
- Arachchige LAJJ
- Arafa O
- Arafa S
- Arango MCM
- Arango MCM
- Aranzabal Durand SY
- Araujo R
- Arcudi C
- Ardley R
- Arenas A
- Arevalo Azmitia JR
- Arias Pacheco RD
- Arman S
- Arman S
- Armando ChunguiBravo J
- Armellini A
- Arnaud A
- Arnaud AP
- Arnaud AP
- Arnaud AP
- Arroyo Basto CA
- Arshad MM
- Arslan E
- Arsyad HM
- Arthur T
- Arulampalam T
- Aruldas N
- Asal M
- Asar YH
- Asare-Bediako K
- Asele FA
- Ashour A
- Ashour A
- Ashour K
- Ashraf SF
- Ashtari M
- Ashton A
- Asi F
- Asilah SMD
- Assal A
- Assouto PA
- Asturia S
- Asumah H
- Ata A
- Ata AAA
- Ata AY
- Atiyeh A
- Atkins ET
- Atkinson K
- Atobatele K
- Attallah NA
- Attard M
- Attia A
- Attia AM
- Augestad KM
- Aung KP
- Austraite A
- Aviles S
- Avoka A
- Awad I
- Awad SA
- Awadallah S
- Awuku-Asabre J
- Ayad S
- Ayandipo O
- Ayandipo OO
- Aydin MC
- Ayyar S
- Aziz DNA
- Aziz MRA
- Aziz NA
- Azizeldine MG
- Azmitia Mendizabal CA
- Azodo IA
- Azzie G
- Azzie G
- Azzis O
- Baba S
- Bachri H
- Badawy M
- Badenjki MA
- Badicel M
- Badr A
- Badr MFM
- Badwi NM
- Badwi NM
- Badwy A
- Bahar S
- Baheeg M
- Bailey K
- Baillie K
- Baillie K
- Baird A
- Bakhaidar M
- Baki BE
- Bakr A
- Bakry HM
- Bala M
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- Chong CL
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- Devadasar GH
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- Donoghue D
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- El Halawany M
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- El Kholy A
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- El Mesery S
- El Sayed GS
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- El Shoura Y
- El-badawy HA
- El-Dien KS
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- El-Din RA
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- El-Kashef H
- El-Latif NK
- El-Ma'doul AS
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- El-Sagheer N
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- El-Shahat NS
- El-Sheemy H
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- Elashmawy M
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- Elazoul M
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- Elbisomy KH
- Eldafrawy M
- Eldamaty L
- Eldeeb AZ
- Eldeen EA
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- Elebute O
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- Elena G
- Elfarargy A
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- Elfiky M
- Elfil M
- Elfouly N
- Elfouly N
- Elfouly Y
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- Elgendy AH
- Elgendy FI
- Elgheriany M
- Elhadad A
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- Elhadry S
- Elhalawany E
- Elhamouly S
- Elhelbawy MS
- Elhendawy A
- Elhendawy AOA
- Elhoseny G
- Elhusseiny AAE
- Elizabeth Lopez C
- Elkadsh I
- Elkady F
- Elkelany A
- Elkelany A
- Elkelany A
- Elkelany A
- Elkhadrawi M
- Elkhalek EA
- Elkholy A
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- Elnajjar MA
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- Elrazek AA
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- Elsameea AA
- Elsawahly DME
- Elsawy A
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- Elsemelawy R
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- Elsheikh S
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- Elsherbiny AS
- Elsherif FA
- Elshobary M
- Elsiddig M
- Elsobky S
- Elsorogy DEAA
- Elwaey A
- Elwakil H
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- Elwy E
- Elzahed N
- Elzayat I
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- Elzowawi F
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- Emara E
- Emile S
- Eng C
- English W
- Esam A
- Escalante Salas MDC
- Espin-Basany E
- Espinoza F
- Essam A
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- Essam M
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- Esteban E
- Estee MM
- Estupinian S
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- Etienne S
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- Evajelista CV
- Evans D
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- Faccincani R
- Fadel A
- Fahiem A
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- Farouk SAM
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy AM
- Fattah AA
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe CO
- Fergany A
- Fergusson SJ
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- Fernandes C
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- Filatau A
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- Frisk B
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- Halicioglu I
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- Ibrahim A
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- Kamarulzamil SNA
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- Kamya S
- Kanani A
- Kandil AM
- Kandil H
- Kang MK
- Kanta TH
- Karabacak U
- Karabelias G
- Karabulut K
- Karahan SR
- Karakahya M
- Karandikar S
- Karandikar S
- Kariem N
- Karim A
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- Karjiker P
- Karkeet M
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- Karlo R
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- Karousos D
- Karumnas P
- Kaselis N
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- Kasem E
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- Kasputyte S
- Kaul A
- Kazanavicius D
- Kedar A
- Kefalidi E
- Keke KR
- Kelany M
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- Kennedy ED
- Kennedy M
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- Kesinger M
- Khafagy T
- Khairy H
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- Khajanchi M
- Khaled H
- Khalifah E
- Khalili M
- Khalique A
- Khallaf S
- Khamajeet A
- Khan A
- Khan K
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- Khan R
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- Khan T
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- Khatri C
- Khatri C
- Khattab K
- Khedr AE-RH
- Khoja A
- Khoja A
- Khokha D
- Khokha V
- Khosla S
- Khouri Ferreira SA
- Khreishi R
- Khreishi R
- Khulu LB
- Khyrallh A
- Kiasat A
- Kidd T
- Kielty P
- Kim MY-H
- Kim S-H
- Kim SB
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- Kinandu K
- King R
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- Kiran RP
- Kirby A
- Kirishnan A
- Kirupagaran A
- Kiudelis M
- Kjellin A
- Klappenbach R
- Knight S
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- Koay KL
- Kobal BB
- Koh C
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- Koh PY
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- Kojo ATT
- Kojo ATT
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- Kolosov A
- Komolafe O
- Kondrotas P
- Kong C
- Kong SN
- Kong V
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- Konstantina K
- Kontos M
- Kordorwu HEK
- Korkolis D
- Kosai NR
- Kosai NR
- Kose E
- Koskenvuo L
- Kostov E
- Kotb AHE-B
- Kotecha D
- Koto MZ
- Kotobi H
- Koumpa F
- Kouraklis G
- Kourdouli A
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- Kretzmann H
- Krishna K
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- Kyriazanos I
- Kyrou G
- Kyziridis D
- L'Heveder A
- La Brocca A
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- Labib P
- Ladukas A
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- Lakshmi HN
- Lam FY
- Lam JCY
- Lam WH
- Lamanna GL
- Lanau MIV
- Lando J
- Landolfo G
- Landolfo G
- Lap G
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- Lasheen A
- Lasheen KT
- Latif A
- Laugzemys E
- Laugzemys E
- Laurie K
- Lauzikas G
- Law JH
- Lawal A
- Lawal AO
- Lawal T
- Lawal TA
- Lawani I
- Lawther R
- Lazzari G
- Lazzari V
- Lazzarini Cury AD
- Le VTH
- Leal A
- Leal M
- Leanne Almanon C
- Lecompte J-F
- Lee C
- Lee EX
- Lee F
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- Lee KY
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- Leppaniemi A
- Leppaniemi A
- Leroux J
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- Leusink A
- Lewis J
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- Li KKK
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- Liew I
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- Lilford R
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- Lim G
- Lim H
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- Lim PJ
- Lim SJ
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- Lim SY
- Limache S
- Limaye N
- Limoges B
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- lo Conte A
- loaloa MR
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- Macchitella Y
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- Macfarlane A
- Machaca M
- Machain Vega GM
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- Maciejec L
- Madiba T
- Madkor MH
- Madrid Barrientos LA
- Maffioli A
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- Magdy H
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- Magee C
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- Manfreda S
- Mangan C
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- Manipal CE
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- Marroquin Rodriguez DE
- Marshall DC
- Martian B-V
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- Mironescu A
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- Mirza A
- Mirza S
- Mistry A
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- Mitroudi M
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- Moe TT
- Mogan YP
- Moghazy ME
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- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed MA
- Mohamed MAEH
- Mohamed MM
- Mohamed O
- Mohamed SR
- Mohameden A
- Mohammad A
- Mohammad A
- Mohammed A
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- Mohammed MMH
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- Monteleone M
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- Montes I
- Montes I
- Montoya Botero JA
- Montrimaite M
- Montrimaite M
- Moodley Y
- Moore R
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- Mora JJV
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- Morandi E
- Moreira G
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- Mosalum O
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- Mostafa M
- Mousa M
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- Nepogodiev D
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- Nwabuoku E
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- Razmdjou S
- Razuri C
- Razzaque J
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- Rocke A
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- Rodriguez-Uria R
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- Rosenberg GS
- Roslani AC
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- Rudzenskaite A
- Ruiz Panez W
- Ruiz-Tovar J
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- Runigamugabo E
- Russo AA
- Rutkowski W
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- Saad MM
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- Saad S
- Saadeh R
- Saami M
- Saar S
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- Sabour FA
- Sabry A
- Sacco M
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- Sadek A
- Sadig N
- Saeed AM
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- Saeed M
- Safa H
- Sahbaz NA
- Sahel S
- Saidbadr A
- Sakr A
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- Sakr R
- Salah A
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- Salah OM
- Salama M
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- Sallinen V
- Sallinen V
- Salma M
- Salma M
- Salma U
- Salman A
- Salusso P
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- Samalavicius NE
- Samaraweera DI
- Samih H
- Samir A
- Samison LH
- Sammarco G
- Sammut K
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- Samson G
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- Samy M
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- Samy S
- Sanad A
- Sanchez Samaniego C
- Sanchez B
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- Sandler S
- Sandoval Barrantes AM
- Sanni HA
- Sanz S
- Sapci I
- Saqlain M
- Sarafilovic H
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- Sasia D
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- Scalabre A
- Scalabre A
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- Schiavone R
- Schivo D
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- Scott M
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- Semeda N
- Semiz A
- Sena-Ruiz F
- Senanayake KJ
- Senanayake WSMKJ
- Setiawan J
- Seto DM
- Seyoum N
- Sfougaris D
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- Shaalan M
- Shabkah A
- Shachykava T
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- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
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- de Leó
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- de Lima CVB
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- Dell A
- Dempster E
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- El-Latif Nka
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- Farouk Sam
- Farquharson A
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- Fattah Aa
- Fatuga A
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- Faturoti O
- Faure A
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- Fawzy A
- Feidantsis T
- Felipe Co
- Fergany A
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- Kim Sh
- Kimaro M
- Kinandu K
- King R
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- Kinnera Sv
- Kiran Rp
- Kirby A
- Kirishnan A
- Kirupagaran A
- Kiudelis M
- Kjellin A
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- Klappenbach R
- Knight S
- Koay Kl
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- Kolosov A
- Komolafe O
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- Kong C
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- Kosai Nr
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- Kose E
- Koskenvuo L
- Kostov E
- Kotb Ahe
- Kotecha D
- Koto Mz
- Kotobi H
- Koumpa F
- Kouraklis G
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- Kretzmann H
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- Kwatiwani C
- Kwizera S
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- Kyriazanos I
- Kyrou G
- Kyziridis D
- Ló
- L&apos
- La Brocca A
- la Medina AR
- la Medina AR
- la Medina AR
- Labib P
- Ladukas A
- Lafferty K
- Lagunavicius K
- Lai Ac
- Lakhani Sm
- Lakshmi Hn
- Lam Fy
- Lam Jcy
- Lam Wh
- Lamanna Gl
- Lanau Miv
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- Lap G
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- Larsen Jw
- Lasek A
- Lasheen A
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- Latif A
- Laufer Lav
- Laugzemys E
- Laugzemys E
- Laurie K
- Lauzikas G
- Law Jh
- Lawal A
- Lawal Ao
- Lawal T
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- Lawani I
- Lawther R
- Lazzari G
- Lazzari V
- Leal A
- Leal M
- Lecompte Jf
- Lee C
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- Lee F
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- Lee Kc
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- Leone N
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- Leung Kw
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- Leusink A
- Lewis J
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- Lilford R
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- Lim G
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- Loaloa Mr
- Lockey J
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- Loizides S
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- Lorenzon L
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- Low X
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- Mabrouk M
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- Macchitella Y
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- Macfarlane A
- Machaca M
- Maciejec L
- Madiba T
- Madkor Mh
- Maffioli A
- Maffioli A
- Magdy A
- Magdy B
- Magdy E
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- Magdy M
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- Magee C
- Maghrabi A
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- Maharaj G
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- Margaritis M
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- Marinkovic B
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- Marks E
- Marples L
- Marret Jb
- Marshall Dc
- Martian Bv
- Martin A
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- Mendoza I
- Menegussi J
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- Mentula P
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- Miranda C
- Mircea H
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- Mirza A
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- Mistry A
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- Modolo Mm
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- Mogan Yp
- Moghazy Me
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- Mohamed Am
- Mohamed Ar
- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed Ma
- Mohamed Maeh
- Mohamed Mm
- Mohamed O
- Mohamed Sr
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- Mohammad A
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- Mohammed S
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- Molina G
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- Monaghan E
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- Monrad-Hansen Pw
- Montejo Msg
- Monteleone M
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- Montes I
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- Montrimaite M
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- Moodley Y
- Moore R
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- Mora Jjv
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- Moreira G
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- Mosalum O
- Mostafa Ha
- Mostafa M
- Mostafa M
- Mousa M
- Moussa O
- Moustafa A
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- Mowafy B
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- Mshelbwala P
- Msiska N
- Msosa V
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- Muddebihal U
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- Mukuzunga C
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- Nanthakumaran S
- Napolitano L
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- Naqvi Sa
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- Naranjo Aristizã
- Narayanan R
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- Negida A
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- Nepogodiev D
- Nepogodiev D
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- Nesaratnam A
- Nessa A
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- Nevieraite V
- Newton T
- Ng S
- Ng Yk
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- Nikoloudis N
- Nikoloudis N
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- Njokanma I
- Nnajiuba H
- Nocito A
- Nocito A
- Nofal E
- Noor F
- Normile C
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- Notarnicola M
- Notarnicola M
- Nouh T
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- Noukpozounkou B
- Novak A
- Nowers J
- Nsengimana Vjp
- Nsengiyumva C
- Ntirenganya F
- Nur&apos
- Nurqistan Hd
- Nwabuoku E
- Nwinee V
- Nwokoro C
- Nyberg J
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- O&apos
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- Odeyemi B
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- Odutola O
- Ogunsua O
- Ogunyemi A
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- Olaolorun A
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- Samaniego Cs
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- Snyder E
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- Sodde P
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- Sokratous A
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- Soldevila-Verdeguer C
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- Soliman N
- Soliman Na
- Soliman S
- Soliman Y
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- Publication venue
- 'Wiley'
- Publication date
- 27/11/2018
- Field of study
Background
End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection.
Methods
This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model.
Results
In total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6·9 per cent) from low-HDI, 254 (15·5 per cent) from middle-HDI and 1268 (77·6 per cent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57·5, 40·9 and 35·4 per cent; P < 0·001) and subsequent use of end colostomy (52·2, 24·8 and 18·9 per cent; P < 0·001) in low- compared with middle- and high-HDI settings. The association with colostomy use in low-HDI settings persisted (odds ratio (OR) 3·20, 95 per cent c.i. 1·35 to 7·57; P = 0·008) after risk adjustment for malignant disease (OR 2·34, 1·65 to 3·32; P < 0·001), emergency surgery (OR 4·08, 2·73 to 6·10; P < 0·001), time to operation at least 48 h (OR 1·99, 1·28 to 3·09; P = 0·002) and disease perforation (OR 4·00, 2·81 to 5·69; P < 0·001).
Conclusion
Global differences existed in the proportion of patients receiving end stomas after left-sided colorectal resection based on income, which went beyond case mix alone
Characterization and biological properties of a novel synthesized silicon-substituted hydroxyapatite derived from eggshell
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Thigh-length compression stockings and DVT after stroke
- Author
- Abbas M
- Abbasi S
- Abbasi S
- Abdelaziz A
- Abdelfattah M
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- Abdulmumeen A
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- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/1994
- Field of study
Controversy exists as to whether neoadjuvant chemotherapy improves survival in patients with invasive bladder cancer, despite randomised controlled trials of more than 3000 patients. We undertook a systematic review and meta-analysis to assess the effect of such treatment on survival in patients with this disease
Does Salicylic Acid (SA) Improve Tolerance to Salt Stress in Plants? A Study of SA Effects On Tomato Plant Growth, Water Dynamics, Photosynthesis, and Biochemical Parameters
- Author
- Publication venue
- 'Mary Ann Liebert Inc'
- Publication date
- Field of study