Analysis of the Lump Wood Burning Process

Diplomová práce se zabývá analýzou procesu hoření dřevěných briket v teplovodní krbové vložce. V práci je teoreticky popsána struktura dřeva, změny dřevní struktury při zahřívání a proces spalování dřeva. Ke zkoumání dřevní struktury se použil termogravimetrický analyzátor. Termogravimetrické analýzy byly provedeny v inertní a oxidační atmosféře. Měřily se emise a teploty v briketě během spalování brikety v krbové vložce. Z emisí se vypočetl hmotnostní úbytek uhlíku z brikety v průběhu spalovacího procesu. Z naměřených teplot a poznatků z termogravimetrické analýzy byl vytvořen teplotní model dřevěné brikety. Z teplotního modelu se stanovil hmotnostní úbytek vodíku, kyslíku a vody z brikety v průběhu spalovacího procesu.Master thesis is dealing with analysis of the lumb wood burning proces at the fireplace insert. The structure of wood, changes in wood structure during heating and wood burning process is theoretically described in the thesis. Changes of wood structur were investigated using a termogravimetric analyzator. Thermogravimetric analysis were realized in an inert and oxidative atmosphere. Emissions and temperatures in the lump wood were measured during combustion in the fireplace insert. From the emissions were calculated the weight loss of carbon from the lump wood during the combustion process. From the measured temperatures and knowledge form thermogravimetric analysis was created the temperature model of lump wood. From the temperature model was determined the weight loss of hydrogen, oxygen and water from the lump wood during the combustion process.361 - Katedra energetikyvýborn

Design and Calculation Stove with Water Heat Exchanger

Import 02/11/2016Práce se zabývá návrhem a výpočtem teplovodního výměníku umístěného ve dvanácti kilowattových krbových kamnech. V úvodu jsou srovnány tři druhy krbových kamen dle přestupu tepla a rozvodu tepla po vytápěném objektu. Jsou popsány dva typy teplovodních výměníku využívaných u krbových kamen. Návrh výměníku spočívá ve volbě typu výměníku, jeho rozměrů a materiálu tak, aby byl dosažen výkon výměníku 8 kW. Pro výpočet jsou použity stechiometrické rovnice a rovnice ze sdílení tepla.The thesis deals with design and calculation of water heat exchager located in the twelve kilowatts wood burning stove. At the beginning are compared free types of stove by heat exchange and distribution of heat at the heated object. Are described two kinds of water heat exchanger using in the wood burning stove. Design of the water heat exchanger consists of selecting the type of exchanger, its dimensions and material so that power of exchanger attained eight kilowatts. For the calculation are used stoichiometric and heat transfer formulas.361 - Katedra energetikyvýborn

Bacterial Isolates and Antibiotic Sensitivity among Gambian Children with Severe Acute Malnutrition

Background. Establishing the pattern of infection and antimicrobial sensitivities in the local environment is critical to rational use of antibiotics and the development of management algorithms. Methods. Morbidity history and physical examination of 140 children with severe acute malnutrition were recorded. Their blood, stool, and urine samples were cultured and antibiotic sensitivity patterns determined for any bacterial pathogens isolated. Results. Thirty-eight children had a pathogen isolated from blood culture, 60% of which were considered contaminants. Coagulase negative staphylococcus was the predominant contaminant, while the major causes of bacteraemia were nontyphoidal Salmonella (13%), S. pneumoniae (10%), and E. coli (8%). E. coli accounted for 58% of the urinary isolates. No pathogen was isolated from stool. In vitro sensitivity by disk diffusion showed that 87.5% of the isolates were sensitive to ampicillin and/or gentamicin and 84.4% (27/32) to penicillin and/or gentamicin. Conclusions. A combination of ampicillin and gentamicin provides adequate antibiotic cover for severely malnourished children in The Gambia

Long-term neutralization of acidic condensate from gas condensing boilers

The pH of wastewater needs to remain between 6 and 9 to protect water organisms. Condensates from a gas condensing boiler have a pH value of about 3. An optimal way to neutralize the acid condensate is to use cheap material such as dolomite. An old-style neutralization box (NB) was tested with a standard faction of dolomite. However, it did not sufficiently neutralize the condensate. Therefore, several tests were performed involving changes to the construction of the neutralization box, a finer fraction of dolomite and aerating the condensate in the neutralization box. In summary, a new NB technology with partitions, a finer fraction of dolomite and condensate aeration proved sufficient in the neutralization of the pH of the condensate in the short and long terms. It depends on what material the heat exchanger is made of in the condensing boiler. The aluminum content reduces the effectiveness of dolomite in the long run, so aerating the condensate in the NB is recommended, which leads to its more effective neutralization.Web of Science1422art. no. 1501

Highly Accurate Diagnosis of Pleural Tuberculosis by Immunological Analysis of the Pleural Effusion

Pleural TB is notoriously difficult to diagnose due to its paucibacillary nature yet it is the most common cause of pleural effusions in TB endemic countries such as The Gambia. We identified both cellular and soluble biomarkers in the pleural fluid that allowed highly accurate diagnosis of pleural TB compared to peripheral blood markers. Multi-plex cytokine analysis on unstimulated pleural fluid showed that IP-10 resulted in a positive likelihood ratio (LR) of 9.6 versus 2.8 for IFN-γ; a combination of IP-10, IL-6 and IL-10 resulted in an AUC of 0.96 and positive LR of 10. A striking finding was the significantly higher proportion of PPD-specific IFN-γ+TNF-α+ cell population (PPD-IGTA) in the pleural fluid compared to peripheral blood of TB subjects. Presence of this pleural PPD-IGTA population resulted in 95% correct classification of pleural TB disease with a sensitivity of 95% and specificity of 100%. These data suggest that analysis of the site of infection provides superior diagnostic accuracy compared to peripheral blood for pleural TB, likely due to the sequestration of effector cells at this acute stage of disease

Motzkin monoids and partial Brauer monoids

We study the partial Brauer monoid and its planar submonoid, the Motzkin monoid. We conduct a thorough investigation of the structure of both monoids, providing information on normal forms, Green's relations, regularity, ideals, idempotent generation, minimal (idempotent) generating sets, and so on. We obtain necessary and sufficient conditions under which the ideals of these monoids are idempotent-generated. We find formulae for the rank (smallest size of a generating set) of each ideal, and for the idempotent rank (smallest size of an idempotent generating set) of the idempotent-generated subsemigroup of each ideal; in particular, when an ideal is idempotent-generated, the rank and idempotent rank are equal. Along the way, we obtain a number of results of independent interest, and we demonstrate the utility of the semigroup theoretic approach by applying our results to obtain new proofs of some important representation theoretic results concerning the corresponding diagram algebras, the partial (or rook) Brauer algebra and Motzkin algebra

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

A Research Agenda for Helminth Diseases of Humans: Intervention for Control and Elimination

Recognising the burden helminth infections impose on human populations, and particularly the poor, major intervention programmes have been launched to control onchocerciasis, lymphatic filariasis, soil-transmitted helminthiases, schistosomiasis, and cysticercosis. The Disease Reference Group on Helminth Infections (DRG4), established in 2009 by the Special Programme for Research and Training in Tropical Diseases (TDR), was given the mandate to review helminthiases research and identify research priorities and gaps. A summary of current helminth control initiatives is presented and available tools are described. Most of these programmes are highly dependent on mass drug administration (MDA) of anthelmintic drugs (donated or available at low cost) and require annual or biannual treatment of large numbers of at-risk populations, over prolonged periods of time. The continuation of prolonged MDA with a limited number of anthelmintics greatly increases the probability that drug resistance will develop, which would raise serious problems for continuation of control and the achievement of elimination. Most initiatives have focussed on a single type of helminth infection, but recognition of co-endemicity and polyparasitism is leading to more integration of control. An understanding of the implications of control integration for implementation, treatment coverage, combination of pharmaceuticals, and monitoring is needed. To achieve the goals of morbidity reduction or elimination of infection, novel tools need to be developed, including more efficacious drugs, vaccines, and/or antivectorial agents, new diagnostics for infection and assessment of drug efficacy, and markers for possible anthelmintic resistance. In addition, there is a need for the development of new formulations of some existing anthelmintics (e.g., paediatric formulations). To achieve ultimate elimination of helminth parasites, treatments for the above mentioned helminthiases, and for taeniasis and food-borne trematodiases, will need to be integrated with monitoring, education, sanitation, access to health services, and where appropriate, vector control or reduction of the parasite reservoir in alternative hosts. Based on an analysis of current knowledge gaps and identification of priorities, a research and development agenda for intervention tools considered necessary for control and elimination of human helminthiases is presented, and the challenges to be confronted are discussed

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities(.)(1,2) This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity(3-6). Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017-and more than 80% in some low- and middle-income regions-was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing-and in some countries reversal-of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories.Peer reviewe