816 research outputs found
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Role of kinesins in directed adenovirus transport and cytoplasmic exploration
- Publication venue
- 'Columbia University Libraries/Information Services'
- Publication date
- 01/01/2018
- Field of study
Many viruses, including adenovirus, exhibit bidirectional transport along microtubules following cell entry. Cytoplasmic dynein is responsible for microtubule minus end transport of adenovirus capsids after endosomal escape. However, the identity and roles of the opposing plus end-directed motor(s) remain unknown. We performed an RNAi screen of 38 kinesins, which implicated Kif5B (kinesin-1 family) and additional minor kinesins in adenovirus 5 (Ad5) capsid translocation. Kif5B RNAi markedly increased centrosome accumulation of incoming Ad5 capsids in human A549 pulmonary epithelial cells within the first 30 min post infection, an effect dramatically enhanced by blocking Ad5 nuclear pore targeting using leptomycin B. The Kif5B RNAi phenotype was rescued by expression of RNAi-resistant Kif5A, B, or C, and Kif4A. Kif5B RNAi also inhibited a novel form of microtubule-based âassisted-diffusionâ behavior which was apparent between 30 and 60 min p.i. We found the major capsid protein penton base (PB) to recruit kinesin-1, distinct from the hexon role we previously identified for cytoplasmic dynein binding. We propose that adenovirus uses independently recruited kinesin and dynein for directed transport and for a more random microtubule-based assisted diffusion behavior to fully explore the cytoplasm before docking at the nucleus, a mechanism of potential importance for physiological cargoes as well
Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism
- Author
- Publication venue
- 'Columbia University Libraries/Information Services'
- Publication date
- 01/01/2016
- Field of study
Small GTPases play a critical role in membrane traffic. Among them, Arf6 mediates transport to and from the plasma membrane, as well as phosphoinositide signalling and cholesterol homeostasis. Here we delineate the molecular basis for the link between Arf6 and cholesterol homeostasis using an inducible knockout (KO) model of mouse embryonic fibroblasts (MEFs). We find that accumulation of free cholesterol in the late endosomes/lysosomes of Arf6 KO MEFs results from mistrafficking of NiemannâPick type C protein NPC2, a cargo of the cation-independent mannose-6-phosphate receptor (CI-M6PR). This is caused by a selective increase in an endosomal pool of phosphatidylinositol-4-phosphate (PI4P) and a perturbation of retromer, which controls the retrograde transport of CI-M6PR via sorting nexins, including the PI4P effector SNX6. Finally, reducing PI4P levels in KO MEFs through independent mechanisms rescues aberrant retromer tubulation and cholesterol mistrafficking. Our study highlights a phosphoinositide-based mechanism for control of cholesterol distribution via retromer
Genetic Drivers of Heterogeneity in Type 2 Diabetes Pathophysiology
- Author
- Adair Linda S
- Adeyemo Adebowale
- Aguilar-Salinas Carlos A
- Ahlqvist Emma
- Ahluwalia Tarunveer S
- Ahsan Habibul
- An Ping
- Anand Sonia S
- Arruda Ana Luiza
- Becker Diane M
- Below Jennifer E
- Bertoni Alain
- Bharadwaj Dwaipayan
- Bielak Lawrence F
- Bocher Ozvan
- Boehnke Michael
- Bonnefond Amélie
- Bork-Jensen Jette
- Bowden Donald W
- Bragg Fiona
- Brandslund Ivan
- Broadaway K Alaine
- Brody Jennifer A
- Buchanan Thomas A
- Burant Charles F
- Butterworth Adam S
- Cade Brian E
- Canouil Mickaël
- Chai Jin-Fang
- Chambers John C
- Chan Juliana C N
- Chandak Giriraj R
- Chang Kyong-Mi
- Chang Li-Ching
- Chee Miao-Li
- Chen Chien-Hsiun
- Chen Guanjie
- Chen Ji
- Chen Shyh-Huei
- Chen Wei-Min
- Chen Yii-Der Ida
- Chen Yuan-Tsong
- Chen Zhengming
- Cheng Ching-Yu
- Cho Yoon Shin
- Choi Hyeok Sun
- Chuang Lee-Ming
- Collins Francis S
- Cook James P
- Cruz Miguel
- Cui Jinrui
- Cushman Mary
- Danesh John
- Das Swapan K
- de Silva H Janaka
- Dedoussis George
- Denny Joshua C
- Dimitrov Latchezar
- Doumatey Ayo P
- Du Shufa
- Duan Qing
- Dupuis Josee
- Eckardt Kai-Uwe
- Emery Leslie S
- Engert James C
- Evans Daniel S
- Evans Michele K
- Finer Sarah
- Fischer Krista
- Florez Jose C
- Floyd James S
- Ford Ian
- Fornage Myriam
- Franco Oscar H
- Frayling Timothy M
- Freedman Barry I
- Froguel Philippe
- Genter Pauline
- Gerstein Hertzel C
- Ghanbari Mohsen
- Giedraitis Vilmantas
- Gieger Christian
- GonzĂĄlez-Villalpando Clicerio
- GonzĂĄlez-Villalpando Maria Elena
- Goodarzi Mark O
- Gordon-Larsen Penny
- Graff Mariaelisa
- Grallert Harald
- Grarup Niels
- Gross Myron
- Guare Lindsay A
- Guo Xiuqing
- Hackinger Sophie
- Hai Yang
- Haiman Christopher A
- Hakaste Liisa
- Han Sohee
- Hanis Craig L
- Hansen Torben
- Hattersley Andrew T
- Hatzikotoulas Konstantinos
- Hayes M Geoffrey
- Herder Christian
- Horikoshi Momoko
- Howard Annie-Green
- Hsueh Willa
- Huang Mengna
- Huang Wei
- Huerta-Chagoya Alicia
- Hung Yi-Jen
- Hwang Mi Yeong
- Hwu Chii-Min
- Ichihara Sahoko
- Igase Michiya
- Ikram Mohammad Arfan
- Ingelsson Erik
- Ingelsson Martin
- Ipp Eli
- Islam Md Tariqul
- Isono Masato
- Jang Hye-Mi
- Jasmine Farzana
- Jiang Guozhi
- Jonas Jost B
- Joo Yoonjung Yoonie
- Jukema J Wouter
- JĂžrgensen Torben
- Kabagambe Edmond
- Kadowaki Takashi
- Kals Mart
- Kamali Zoha
- Kamanu Frederick K
- Kandeel Fouad R
- Kanoni Stavroula
- Kardia Sharon L R
- Kasturiratne Anuradhani
- Kato Norihiro
- Katsuya Tomohiro
- Kaur Varinderpal
- Kawaguchi Takahisa
- Keaton Jacob M
- Kho Abel N
- Khor Chiea-Chuen
- Kibriya Muhammad G
- Kim Bong-Jo
- Kim Duk-Hwan
- Kim Young Jin
- Koh Woon-Puay
- Kooner Jaspal S
- Kooperberg Charles
- Kronenberg Florian
- Kuusisto Johanna
- Kwak Soo-Heon
- Köttgen Anna
- Laakso Markku
- Lamri Amel
- Lange Leslie A
- Langenberg Claudia
- Lee Jung-Jin
- Lee Juyoung
- Lee Kyung Min
- Lee Myung-Shik
- Lee Nanette R
- Lee Simon S K
- Leong Aaron
- Li Liming
- Li Yun
- Li-Gao Ruifang
- Ligthart Symen
- Lim Victor J Y
- Lin Kuang
- Lind Lars
- Lindgren Cecilia M
- Linneberg Allan
- Liu Ching-Ti
- Liu Jianjun
- Liu Simin
- Liu Yongmei
- Locke Adam E
- Long Jirong
- Loos Ruth J F
- Lorenz Kim M
- Louie Tin
- Luan Jian\u27an
- Luk Andrea O
- Luo Xi
- Lv Jun
- Lynch Julie A
- Lyssenko Valeriya
- LĂ€ll Kristi
- Ma Ronald C W
- Maeda Shiro
- Mahajan Anubha
- Mamakou Vasiliki
- Mandla Ravi
- Mansuri Sohail Rafik
- Marston Nicholas A
- Matsuda Fumihiko
- Matsuda Koichi
- McCarthy Mark I
- McKean-Cowdin Roberta
- Meigs James B
- Meitinger Thomas
- Melander Olle
- Melloni Giorgio E M
- Mercader Josep M
- Metspalu Andres
- Millwood Iona Y
- Mo Huan
- Mohlke Karen L
- Mook-Kanamori Dennis O
- Moon Sanghoon
- Morris Andrew D
- Morris Andrew P
- Motala Ayesha A
- Moura Filipe A
- MĂ€gi Reedik
- Nadler Jerry L
- Nakatochi Masahiro
- Nalls Michael A
- Namba Shinichi
- Nano Jana
- Nayak Uma
- Ng Maggie C Y
- Nicolas Aude
- Nongmaithem Suraj S
- Noordam Raymond
- North Kari E
- Nousome Darryl
- Ntalla Ioanna
- Okada Yukinori
- Orozco Lorena
- Palmer Colin N A
- Pan Ian
- Pankow James S
- Park Kyong-Soo
- Parra Esteban J
- Paré Guillaume
- Patel Sanjay R
- Patil Snehal
- Pedersen Oluf
- Pei Pei
- Pereira Mark A
- Peters Annette
- Petty Lauren E
- Peyser Patricia A
- Pirie Fraser J
- Polikowsky Hannah G
- Porneala Bianca
- Prasad Gauri
- Preuss Michael H
- Prins Bram Peter
- Province Michael A
- Psaty Bruce M
- Rader Daniel J
- Raffel Leslie J
- Raffield Laura M
- Rasmussen-Torvik Laura J
- Rayner Nigel W
- Redline Susan
- Reiner Alexander P
- Rich Stephen S
- Ritchie Marylyn D
- Roden Michael
- Rohde Rebecca
- Roll Katheryn
- Rotimi Charles N
- Rotter Jerome I
- Ruff Christian T
- Sabanayagam Charumathi
- Sale MichĂšle M
- Saleheen Danish
- Sandow Kevin
- Sankareswaran Alagu
- Sarnowski Chloé
- Sattar Naveed
- Schroeder Philip
- Schönherr Sebastian
- Scott Robert A
- Shahriar Mohammad
- Shen Botong
- Sheu Wayne H H
- Shi Jinxiu
- Shin Dong Mun
- Shojima Nobuhiro
- Shu Xiao-Ou
- Sim Xueling
- Smith Jennifer A
- So Wing Yee
- Sofer Tamar
- Sonehara Kyuto
- Southam Lorraine
- Spracklen Cassandra N
- StanÄĂĄkovĂĄ Alena
- Stefansson Kari
- Steinthorsdottir Valgerdur
- Stilp Adrienne M
- Strauch Konstantin
- Sun Meng
- Suzuki Ken
- Tabara Yasuharu
- Tai E-Shyong
- Takeuchi Fumihiko
- Taliun Daniel
- Tam Claudia H T
- Tan Jingyi
- Taylor Henry J
- Taylor Kent D
- Thangam Manonanthini
- Thorand Barbara
- Thorleifsson Gudmar
- Thorsteinsdottir Unnur
- Tomlinson Brian
- Tong Lin
- Tran Tam C
- Trompet Stella
- Tsai Fuu-Jen
- Tsao Philip S
- Tuomi Tiinamaija
- Tuomilehto Jaakko
- Tusie-Luna Teresa
- Udler Miriam S
- Valladares-Salgado Adan
- van Dam Rob M
- van Dijk Ko Willems
- van Heel David A
- van Klinken Jan B
- Vanderwerff Brett
- Varma Rohit
- Voight Benjamin F
- Vujkovic Marijana
- Wacher-Rodarte Niels
- Walters Robin G
- Wang Ya-Xing
- Wareham Nicholas J
- Wheeler Eleanor
- Wickremasinghe Ananda R
- Williamson Alice
- Wilson James G
- Witte Daniel R
- Wong Tien-Yin
- Wu Jer-Yuarn
- Wuttke Matthias
- Xiang Anny H
- Yajnik Chittaranjan S
- Yamamoto Ken
- Yamamoto Kenichi
- Yamauchi Toshimasa
- Yanek Lisa R
- Yao Jie
- Yin Xianyong
- Yokota Mitsuhiro
- Yoon Kyungheon
- Yu Canqing
- Yuan Jian-Min
- Yusuf Salim
- Zawistowski Matthew
- Zeggini Eleftheria
- Zhang Liang
- Zhang Weihua
- Zheng Wei
- Zonderman Alan B
- Zöllner Sebastian
- Publication venue
- DigitalCommons@TMC
- Publication date
- 01/03/2024
- Field of study
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes1,2 and molecular mechanisms that are often specific to cell type3,4. Here, to characterize the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study data from 2,535,601 individuals (39.7% not of European ancestry), including 428,452 cases of T2D. We identify 1,289 independent association signals at genome-wide significance (P \u3c 5 Ă 10-8) that map to 611 loci, of which 145 loci are, to our knowledge, previously unreported. We define eight non-overlapping clusters of T2D signals that are characterized by distinct profiles of cardiometabolic trait associations. These clusters are differentially enriched for cell-type-specific regions of open chromatin, including pancreatic islets, adipocytes, endothelial cells and enteroendocrine cells. We build cluster-specific partitioned polygenic scores5 in a further 279,552 individuals of diverse ancestry, including 30,288 cases of T2D, and test their association with T2D-related vascular outcomes. Cluster-specific partitioned polygenic scores are associated with coronary artery disease, peripheral artery disease and end-stage diabetic nephropathy across ancestry groups, highlighting the importance of obesity-related processes in the development of vascular outcomes. Our findings show the value of integrating multi-ancestry genome-wide association study data with single-cell epigenomics to disentangle the aetiological heterogeneity that drives the development and progression of T2D. This might offer a route to optimize global access to genetically informed diabetes care
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
- Author
- Adair Linda S.
- Adeyemo Adebowale
- Aguilar-Salinas Carlos A.
- Ahlqvist Emma
- Ahluwalia Tarunveer S.
- Ahsan Habibul
- An Ping
- Anand Sonia S.
- Arruda Ana Luiza
- Becker Diane M.
- Below Jennifer E.
- Bertoni Alain
- Bharadwaj Dwaipayan
- Bielak Lawrence F.
- Bocher Ozvan
- Boehnke Michael
- Bonnefond Amélie
- Bork-Jensen Jette
- Bowden Donald W.
- Bragg Fiona
- Brandslund Ivan
- Broadaway K. Alaine
- Brody Jennifer A.
- Buchanan Thomas A.
- Burant Charles F.
- Butterworth Adam S.
- Cade Brian E.
- Canouil Mickaël
- Chai Jin-Fang
- Chambers John C.
- Chan Juliana C. N.
- Chandak Giriraj R.
- Chang Kyong-Mi
- Chang Li-Ching
- Chee Miao-Li
- Chen Chien-Hsiun
- Chen Guanjie
- Chen Ji
- Chen Shyh-Huei
- Chen Wei-Min
- Chen Yii-Der Ida
- Chen Yuan-Tsong
- Chen Zhengming
- Cheng Ching-Yu
- Cho Yoon Shin
- Choi Hyeok Sun
- Chuang Lee-Ming
- Collins Francis S.
- Cook James P.
- Cruz Miguel
- Cui Jinrui
- Cushman Mary
- Dam Rob M. van
- Danesh John
- Das Swapan K.
- de Silva H. Janaka
- Dedoussis George
- Denny Joshua C.
- Dijk Ko Willems van
- Dimitrov Latchezar
- Doumatey Ayo P.
- Du Shufa
- Duan Qing
- Dupuis Josee
- Eckardt Kai-Uwe
- Emery Leslie S.
- Engert James C.
- Evans Daniel S.
- Evans Michele K.
- Finer Sarah
- Fischer Krista
- Florez Jose C.
- Floyd James S.
- Ford Ian
- Fornage Myriam
- Franco Oscar H.
- Frayling Timothy M.
- Freedman Barry I.
- Froguel Philippe
- Genter Pauline
- Gerstein Hertzel C.
- Ghanbari Mohsen
- Giedraitis Vilmantas
- Gieger Christian
- GonzĂĄlez-Villalpando Clicerio
- GonzĂĄlez-Villalpando Maria Elena
- Goodarzi Mark O.
- Gordon-Larsen Penny
- Graff Mariaelisa
- Grallert Harald
- Grarup Niels
- Gross Myron
- Guare Lindsay A.
- Guo Xiuqing
- Hackinger Sophie
- Hai Yang
- Haiman Christopher A.
- Hakaste Liisa
- Han Sohee
- Hanis Craig L.
- Hansen Torben
- Hattersley Andrew T.
- Hatzikotoulas Konstantinos
- Hayes M. Geoffrey
- Heel David A. van
- Herder Christian
- Horikoshi Momoko
- Howard Annie-Green
- Hsueh Willa
- Huang Mengna
- Huang Wei
- Huerta-Chagoya Alicia
- Hung Yi-Jen
- Hwang Mi Yeong
- Hwu Chii-Min
- Ichihara Sahoko
- Igase Michiya
- Ikram Mohammad Arfan
- Ingelsson Erik
- Ingelsson Martin
- Ipp Eli
- Islam Md. Tariqul
- Isono Masato
- Jang Hye-Mi
- Jasmine Farzana
- Jiang Guozhi
- Jonas Jost B.
- Joo Yoonjung Yoonie
- Jukema J. Wouter
- JĂžrgensen Torben
- Kabagambe Edmond
- Kadowaki Takashi
- Kals Mart
- Kamali Zoha
- Kamanu Frederick K.
- Kandeel Fouad R.
- Kanona Stavroula
- Kanoni Stavroula
- Kardia Sharon L. R.
- Kasturiratne Anuradhani
- Kato Norihiro
- Katsuya Tomohiro
- Kaur Varinderpal
- Kawaguchi Takahisa
- Keaton Jacob M.
- Kho Abel N.
- Khor Chiea-Chuen
- Kibriya Muhammad G.
- Kim Bong-Jo
- Kim Duk-Hwan
- Kim Young Jin
- Klinken Jan B. van
- Koh Woon-Puay
- Kooner Jaspal S.
- Kooperberg Charles
- Kronenberg Florian
- Kuusisto Johanna
- Kwak Soo-Heon
- Köttgen Anna
- Laakso Markku
- Lamri Amel
- Lange Leslie A.
- Langenberg Claudia
- Lee Jung-Jin
- Lee Juyoung
- Lee Kyung Min
- Lee Myung-Shik
- Lee Nanette R.
- Lee Simon S. K.
- Leong Aaron
- Li Liming
- Li Yun
- Li-Gao Ruifang
- Ligthart Symen
- Lim Victor J. Y.
- Lin Kuang
- Lind Lars
- Lindgren Cecilia M.
- Linneberg Allan
- Liu Ching-Ti
- Liu Jianjun
- Liu Simin
- Liu Yongmei
- Locke Adam E.
- Long Jirong
- Loos Ruth J. F.
- Lorenz Kim M.
- Louie Tin
- Luan Jianâan
- Luk Andrea O.
- Luo Xi
- Lv Jun
- Lynch Julie A.
- Lyssenko Valeriya
- LĂ€ll Kristi
- Ma Ronald C. W.
- Maeda Shiro
- Mahajan Anubha
- Mamakou Vasiliki
- Mandla Ravi
- Mansuri Sohail Rafik
- Marston Nicholas A.
- Matsuda Fumihiko
- Matsuda Koichi
- McCarthy Mark I.
- McKean-Cowdin Roberta
- Meigs James B.
- Meitinger Thomas
- Melander Olle
- Melloni Giorgio E. M.
- Mercader Josep M.
- Metspalu Andres
- Millwood Iona Y.
- Mo Huan
- Mohlke Karen L.
- Mook-Kanamori Dennis O.
- Moon Sanghoon
- Morris Andrew D.
- Morris Andrew P.
- Motala Ayesha A.
- Moura Filipe A.
- MĂ€gi Reedik
- Nadler Jerry L.
- Nakatochi Masahiro
- Nalls Michael A.
- Namba Shinichi
- Nano Jana
- Nayak Uma
- Ng Maggie C. Y.
- Nicolas Aude
- Nongmaithem Suraj S.
- Noordam Raymond
- North Kari E.
- Nousome Darryl
- Ntalla Ioanna
- Okada Yukinori
- Orozco Lorena
- Palmer Colin N. A.
- Pan Ian
- Pankow James S.
- Park Kyong-Soo
- Parra Esteban J.
- Paré Guillaume
- Patel Sanjay R.
- Patil Snehal
- Pedersen Oluf
- Pei Pei
- Pereira Mark A.
- Peters Annette
- Petty Lauren E.
- Peyser Patricia A.
- Pirie Fraser J.
- Polikowsky Hannah G.
- Porneala Bianca
- Prasad Gauri
- Preuss Michael H.
- Prins Bram Peter
- Province Michael A.
- Psaty Bruce M.
- Rader Daniel J.
- Raffel Leslie J.
- Raffield Laura M.
- Rasmussen-Torvik Laura J.
- Rayner Nigel W.
- Redline Susan
- Reiner Alexander P.
- Rich Stephen S.
- Ritchie Marylyn D.
- Roden Michael
- Rohde Rebecca
- Roll Katheryn
- Rotimi Charles N.
- Rotter Jerome I.
- Ruff Christian T.
- Sabanayagam Charumathi
- Sale MichĂšle M.
- Saleheen Danish
- Sandow Kevin
- Sankareswaran Alagu
- Sarnowski Chloé
- Sattar Naveed
- Schroeder Philip
- Schönherr Sebastian
- Scott Robert A.
- Shahriar Mohammad
- Shen Botong
- Sheu Wayne H. H.
- Shi Jinxiu
- Shin Dong Mun
- Shojima Nobuhiro
- Shu Xiao-Ou
- Sim Xueling
- Smith Jennifer A.
- So Wing Yee
- Sofer Tamar
- Sonehara Kyuto
- Southam Lorraine
- Spracklen Cassandra N.
- StanÄĂĄkovĂĄ Alena
- Stefansson Kari
- Steinthorsdottir Valgerdur
- Stilp Adrienne M.
- Strauch Konstantin
- Sun Meng
- Suzuki Ken
- Tabara Yasuharu
- Tai E-Shyong
- Takeuchi Fumihiko
- Taliun Daniel
- Tam Claudia H. T.
- Tan Jingyi
- Taylor Henry J.
- Taylor Kent D.
- Thangam Manonanthini
- Thorand Barbara
- Thorleifsson Gudmar
- Thorsteinsdottir Unnur
- Tomlinson Brian
- Tong Lin
- Tran Tam C.
- Trompet Stella
- Tsai Fuu-Jen
- Tsao Philip S.
- Tuomi Tiinamaija
- Tuomilehto Jaakko
- Tusie-Luna Teresa
- Udler Miriam S.
- Valladares-Salgado Adan
- van Heel David A.
- Vanderwerff Brett
- Varma Rohit
- Voight Benjamin F.
- Vujkovic Marijana
- Wacher-Rodarte Niels
- Walters Robin G.
- Wang Ya-Xing
- Wareham Nicholas J.
- Wheeler Eleanor
- Wickremasinghe Ananda R.
- Williamson Alice
- Wilson James G.
- Witte Daniel R.
- Wong Tien-Yin
- Wu Jer-Yuarn
- Wuttke Matthias
- Xiang Anny H.
- Yajnik Chittaranjan S.
- Yamamoto Ken
- Yamamoto Kenichi
- Yamauchi Toshimasa
- Yanek Lisa R.
- Yao Jie
- Yin Xianyong
- Yokota Mitsuhiro
- Yoon Kyungheon
- Yu Canqing
- Yuan Jian-Min
- Yusuf Salim
- Zawistowski Matthew
- Zeggini Eleftheria
- Zhang Liang
- Zhang Weihua
- Zheng Wei
- Zonderman Alan B.
- Zöllner Sebastian
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes1,2 and molecular mechanisms that are often specific to cell type3,4. Here, to characterize the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study data from 2,535,601 individuals (39.7% not of European ancestry), including 428,452 cases of T2D. We identify 1,289 independent association signals at genome-wide significance (Pâ<â5âĂâ10-8) that map to 611 loci, of which 145 loci are, to our knowledge, previously unreported. We define eight non-overlapping clusters of T2D signals that are characterized by distinct profiles of cardiometabolic trait associations. These clusters are differentially enriched for cell-type-specific regions of open chromatin, including pancreatic islets, adipocytes, endothelial cells and enteroendocrine cells. We build cluster-specific partitioned polygenic scores5 in a further 279,552 individuals of diverse ancestry, including 30,288 cases of T2D, and test their association with T2D-related vascular outcomes. Cluster-specific partitioned polygenic scores are associated with coronary artery disease, peripheral artery disease and end-stage diabetic nephropathy across ancestry groups, highlighting the importance of obesity-related processes in the development of vascular outcomes. Our findings show the value of integrating multi-ancestry genome-wide association study data with single-cell epigenomics to disentangle the aetiological heterogeneity that drives the development and progression of T2D. This might offer a route to optimize global access to genetically informed diabetes care.</p
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants
- Author
- Abarca-Gomez Leandra
- Abdeen Ziad A
- Abdrakhmanova Shynar
- Abu-Rmeileh Niveen M
- Acosta-Cazares Benjamin
- Adams Robert J
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A
- Agyemang Charles
- Ahmad Mohamad Hasnan
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmed Soheir H
- Ahrens Wolfgang
- Aitmurzaeva Gulmira
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Hazzaa Hazzaa M
- Al-Othman Amani Rashed
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Alvarez-Pedrerol Mar
- Aly Eman
- Amarapurkar Deepak N
- Amiri Parisa
- Amougou Norbert
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A
- Angquist Lars
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Aounallah-Skhiri Hajer
- Araujo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E
- Arlappa Nimmathota
- Aryal Krishna K
- Aspelund Thor
- Assah Felix K
- Assuncao Maria Cecilia F
- Aung May Soe
- Auvinen Juha
- Avdicova Maria
- Azevedo Ana
- Azimi-Nezhad Mohsen
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V
- Baharudin Azli
- Bahijri Suhad
- Baker Jennifer L
- Balakrishna Nagalla
- Bamoshmoosh Mohamed
- Banach Maciej
- Bandosz Piotr
- Banegas Jose R
- Baran Joanna
- Barbagallo Carlo M
- Barcelo Alberto
- Barkat Amina
- Barros Aluisio JD
- Barros Mauro Virgilio Gomes
- Basit Abdul
- Bastos Joao Luiz D
- Bata Iqbal
- Batieha Anwar M
- Batista Rosangela L
- Battakova Zhamilya
- Batyrbek Assembekov
- Baur Louise A
- Beaglehole Robert
- Bebakar Wan Mohamad Wan
- Bel-Serrat Silvia
- Belavendra Antonisamy
- Ben Romdhane Habiba
- Benedics Judith
- Benet Mikhail
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- Bentham James
- Bergh Ingunn Holden
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol Heloisa
- Bezerra Jorge
- Bhagyalaxmi Aroor
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- Braeckman Lutgart
- Bragt Marjolijn CE
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- Bruno Graziella
- Bueno-de-Mesquita H Bas
- Bugge Anna
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- Cheng Ching-Yu
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- Chetrit Angela
- Chikova-Iscener Ekaterina
- Chinh Nguyen Huu
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
- Chirita-Emandi Adela
- Chirlaque Maria-Dolores
- Cho Belong
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- Cifkova Renata
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- De Bacquer Dirk
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- De Ridder David
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- El Ati Jalila
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- Garcia-de-la-Hera Manoli
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- Hu Yonghua
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- Khanh Le Nguyen Bao
- Khaw Kay-Tee
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- Kheradmand Motahareh
- Khosravi Alireza
- Khouw Ilse MSL
- Khuong Quynh Long
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- Knoflach Michael
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- Korrovits Paul
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- Kouda Katsuyasu
- Kovacs Viktoria A
- Kowlessur Sudhir
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- Kratzer Wolfgang
- Kriemler Susi
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- Krokstad Steiner
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- Kubinova Ruzena
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- Kusuma Yadlapalli S
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- Kyobutungi Catherine
- Laamiri Fatima Zahra
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- Laid Youcef
- Lam Tai Hing
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- Margozzini Paula
- Marina Loreto Santa
- Markaki Anastasia
- Markey Oonagh
- Marques Larissa Pruner
- Marques-Vidal Pedro
- Marrugat Jaume
- Martin Rosemarie
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- Mediene-Benchekor Sounnia
- Medzioniene Jurate
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- Meisfjord Jorgen
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- Menzano Maria Teresa
- Mereke Alibek
- Meshram Indrapal I
- Metspalu Andres
- Mi Jie
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- Milanovic Sanja Music
- Milkowska Karolina
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- Miranda J Jaime
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- Mirjalili Mohammad Reza
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- Misigoj-Durakovic Marjeta
- Mistretta Antonio
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- Mohammad Kazem
- Mohammadi Zahra
- Mohammadifard Noushin
- Mohammadpourhodki Reza
- Mohamud Wan Nazaimoon Wan
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- Mossakowska Malgorzata
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- Ochoa-Aviles Angelica M
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- Ohara Kumiko
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- Palli Domenico
- Palloni Alberto
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- Panza Francesco
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- Park Soon-Woo
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- Peters Annette
- Petersmann Astrid
- Petkeviciene Janina
- Petrauskiene Ausra
- Petrescu Constanta Huidumac
- Pettenuzzo Emanuela
- Peykari Niloofar
- Pichardo Rafael N
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- Pigeot Iris
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- Pilav Aida
- Pilotto Lorenza
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- Piwonska Aleksandra
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- Porta Miquel
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- Poudyal Anil
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- Quang Ngoc La
- Quang Ngoc Nguyen
- Radic Ivana
- Radisauskas Ricardas
- Rahim Hanan F Abdul
- Rahim Norsyamlina Che Abdul
- Rahimikazerooni Salar
- Rahman Mahfuzar
- Rahman Mahmudur
- Raitakari Olli
- Raj Manu
- Rakhimova Ellina
- Rakhmatulloev Sherali
- Rakovac Ivo
- Ramachandran Ambady
- Ramke Jacqueline
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- Ramos Rafel
- Rampal Lekhraj
- Rampal Sanjay
- Rao Kodavanti Mallikharjuna
- Rao Sudha Ramachandra
- Rarra Vayia
- Rascon-Pacheco Ramon A
- Rasmussen Mette
- Rech Cassiano Ricardo
- Redon Josep
- Reganit Paul Ferdinand M
- Regecova Valeria
- Revilla Luis
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- Ribas-Barba Lourdes
- Ribeiro Robespierre
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- Rinaldo Natascia
- Rito Ana
- Ritti-Dias Raphael M
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- Robitaille Cynthia
- Roccaldo Romana
- Rodrigues Daniela
- Rodriguez-Artalejo Fernando
- Rodriguez-Martinez Andrea
- Rodriguez-Perez Maria del Cristo
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- Rojas-Martinez Rosalba
- Rojroongwasinkul Nipa
- Romaguera Dora
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- Rosario Angelika Schaffrath
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- Ruiz-Betancourt Blanca Sandra
- Rusakova Iuliia A
- Russo Paola
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- Saavedra Maria Angeles Dal Re
- Sabanayagam Charumathi
- Sacchini Elena
- Sachdev Harshpal S
- Sadjadi Alireza
- Safarpour Ali Reza
- Safi Sare
- Safiri Saeid
- Saidi Olfa
- Saki Nader
- Salanave Benoit
- Salmeron Diego
- Salomaa Veikko
- Salonen Jukka T
- Salvetti Massimo
- Samoutian Margarita
- Sanchez-Abanto Jose
- Sandjaja
- Sans Susana
- Sant'Angelo Victoria Farrugia
- Santos Diana A
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- Santos Osvaldo
- Santos Rute
- Sanz Sara Santos
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- Sarrafzadegan Nizal
- Sathish Thirunavukkarasu
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- Wang Ming-Dong
- Wang Ningli
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- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S Goya
- Wareham Nicholas
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- Wedderkopp Niels
- Weerasekera Deepa
- Weghuber Daniel
- Wei Wenbin
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- Widhalm Kurt
- Widyahening Indah S
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- Wilks Rainford J
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- Wong Tien Yin
- Wong-McClure Roy A
- Woo Jean
- Woodward Mark
- Wu Frederick C
- Wu Jianfeng
- Wu Li Juan
- Wu Shouling
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yamborisut Uruwan
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yardim Nazan
- Yaseri Mehdi
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K
- Yoosefi Moein
- Yoshihara Akihiro
- You Qi Sheng
- You San-Lin
- Younger-Coleman Novie O
- Yusof Safiah Md
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zaccagni Luciana
- Zafiropulos Vassilis
- Zainuddin Ahmad A
- Zainuddin Ahmad A
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zamrazilova Hana
- Zapata Maria Elisa
- Zargar Abdul Hamid
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhao Wenhua
- Zhen Shiqi
- Zheng Wei
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhou Maigeng
- Zhu Dan
- Zocalo Yanina
- Zuziak Monika
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study
Summary Background Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. Methods For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a Bayesian hierarchical model to estimate trends from 1985 to 2019 in mean height and mean BMI in 1-year age groups for ages 5â19 years. The model allowed for non-linear changes over time in mean height and mean BMI and for non-linear changes with age of children and adolescents, including periods of rapid growth during adolescence. Findings We pooled data from 2181 population-based studies, with measurements of height and weight in 65 million participants in 200 countries and territories. In 2019, we estimated a difference of 20 cm or higher in mean height of 19-year-old adolescents between countries with the tallest populations (the Netherlands, Montenegro, Estonia, and Bosnia and Herzegovina for boys; and the Netherlands, Montenegro, Denmark, and Iceland for girls) and those with the shortest populations (Timor-Leste, Laos, Solomon Islands, and Papua New Guinea for boys; and Guatemala, Bangladesh, Nepal, and Timor-Leste for girls). In the same year, the difference between the highest mean BMI (in Pacific island countries, Kuwait, Bahrain, The Bahamas, Chile, the USA, and New Zealand for both boys and girls and in South Africa for girls) and lowest mean BMI (in India, Bangladesh, Timor-Leste, Ethiopia, and Chad for boys and girls; and in Japan and Romania for girls) was approximately 9â10 kg/m2. In some countries, children aged 5 years started with healthier height or BMI than the global median and, in some cases, as healthy as the best performing countries, but they became progressively less healthy compared with their comparators as they grew older by not growing as tall (eg, boys in Austria and Barbados, and girls in Belgium and Puerto Rico) or gaining too much weight for their height (eg, girls and boys in Kuwait, Bahrain, Fiji, Jamaica, and Mexico; and girls in South Africa and New Zealand). In other countries, growing children overtook the height of their comparators (eg, Latvia, Czech Republic, Morocco, and Iran) or curbed their weight gain (eg, Italy, France, and Croatia) in late childhood and adolescence. When changes in both height and BMI were considered, girls in South Korea, Vietnam, Saudi Arabia, Turkey, and some central Asian countries (eg, Armenia and Azerbaijan), and boys in central and western Europe (eg, Portugal, Denmark, Poland, and Montenegro) had the healthiest changes in anthropometric status over the past 3·5 decades because, compared with children and adolescents in other countries, they had a much larger gain in height than they did in BMI. The unhealthiest changesâgaining too little height, too much weight for their height compared with children in other countries, or bothâoccurred in many countries in sub-Saharan Africa, New Zealand, and the USA for boys and girls; in Malaysia and some Pacific island nations for boys; and in Mexico for girls. Interpretation The height and BMI trajectories over age and time of school-aged children and adolescents are highly variable across countries, which indicates heterogeneous nutritional quality and lifelong health advantages and risks
Measurement of the W gamma Production Cross Section in Proton-Proton Collisions at root s=13 TeV and Constraints on Effective Field Theory Coefficients
- Author
- Aarrestad Thea Klaeboe
- Aarup Petersen Henriette
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abercrombie Daniel
- Abu Zeid Shimaa
- Acharya Himal
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adamov George
- Adams Eric
- Adams Mark Raymond
- Adams Todd
- Addesa Francesca Maria
- Adloff Catherine
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agarwal Garvita
- Aggleton Robin
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmed Asar
- Ahuja Sudha
- Aime` Chiara
- Akchurin Nural
- Akgun Bora
- Akpinar Alp
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- AldĂĄ JĂșnior Walter Luiz
- Aleksandrov Aleksandar
- Alexander James
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- Zacharopoulou Anna
- Zahid Sema
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- Zalewski Piotr
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- Zarucki Mateusz
- Zecchinelli Angelo Giacomo
- Zeinali Maryam
- Zenaiev Oleksandr
- Zeuner Wolfram Dietrich
- Zghiche Amina
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Sijing
- Zhang Wenyu
- Zhang Yi
- Zhang Zhicai
- Zhao Jingzhou
- Zhemchugov Evgenii
- Zhizhin Ilia
- Zhokin Alexander
- Zhu De Hua
- Zhu Ren-Yuan
- Ziemons Tim
- Zientek Margaret
- Zlebcik Radek
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Zygala Lara
- Ălvarez FernĂĄndez Adrian
- Ăzçelik Ăzlem
- Publication venue
- Publication date
- 01/01/2021
- Field of study
A fiducial cross section for W gamma production in proton-proton collisions is measured at a center-of-mass energy of 13 TeV in 137 fb(-1) of data collected using the CMS detector at the LHC. The W -> e nu and mu nu decay modes are used in a maximum-likelihood fit to the lepton-photon invariant mass distribution to extract the combined cross section. The measured cross section is compared with theoretical expectations at next-to-leading order in quantum chromodynamics. In addition, 95% confidence level intervals are reported for anomalous triple-gauge couplings within the framework of effective field theory.Peer reviewe
Search for dark photons in Higgs boson production via vector boson fusion in proton-proton collisions at âs = 13 TeV
- Author
- Aarrestad Thea Klaeboe
- Aarup Petersen Henriette
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abercrombie Daniel
- Abu Zeid Shimaa
- Acharya Himal
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adams Eric
- Adams Mark Raymond
- Adams Todd
- Adloff Catherine
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agarwal Garvita
- Aggleton Robin
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmed Asar
- Ahuja Sudha
- Aime` Chiara
- Akchurin Nural
- Akgun Bora
- Akpinar Alp
- Albajar Carmen
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- AldĂĄ JĂșnior Walter Luiz
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Alison John
- Allen Brandon
- Almond John
- Alvarez Gonzalez Barbara
- Alverson George
- Alves Gilvan
- Aly Reham
- Alyari Maral
- Amapane Nicola
- Amendola Chiara
- Amin Nick
- Amram Oz
- Amsler Claude
- Anagnostou Georgios
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Antchev Georgy
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Appelt Eric
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Aruta Caterina
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asenov Patrick
- Asghar Muhammad Irfan
- Asilar Ece
- Askew Andrew
- Asmuss Paul
- Atakisi Ismail Okan
- Atanasov Ivan
- Ather Mohsan Waseem
- Attikis Alexandros
- Auffray Etiennette
- Aushev Tagir
- Auzinger Georg
- Avati Valentina
- Avery Paul
- Avila Carlos
- Awais Ali
- Awan Muhammad Imran Malik
- Ayala Edy
- Ayala Gabriel
- Aydogmus Sen Fatma
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzurri Paolo
- Baarmand Marc M
- Babaev Anton
- Babounikau Illia
- Bacchetta Nicola
- Bachiller Irene
- Bachtis Michail
- Backhaus Malte
- Baden Drew
- Baechler Joachim
- Baginyan Andrey
- Bagliesi Giuseppe
- Bahinipati Seema
- Baillon Paul
- Bainbridge Robert
- Bakas Georgios
- Bakhshiansohi Hamed
- Baldenegro Barrera Cristian
- Ball Austin
- Ban Yong
- Band Reyer
- Bandyopadhyay Hirak
- Banerjee Sudeshna
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- Bein Samuel
- Belchior Batista Das Chagas Ewerton
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- Bell Ken W
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- Belyaev Alexander
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- BRANDAO MALBOUISSON Helena
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- Breedon Richard
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- Brochero Cifuentes Javier Andres
- Brom Jean-Marie
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- Brown Robert M
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- Bury Florian Joel J
- Busson Philippe
- Busza Wit
- Butalla Stephen
- Butler Joel Nathan
- Butler Philip H
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- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
A search is presented for a Higgs boson that is produced via vector boson fusion and that decays to an undetected particle and an isolated photon. The search is performed by the CMS collaboration at the LHC, using a data set corresponding to an integrated luminosity of 130 fbâ1, recorded at a center-of-mass energy of 13 TeV in 2016â2018. No significant excess of events above the expectation from the standard model background is found. The results are interpreted in the context of a theoretical model in which the undetected particle is a massless dark photon. An upper limit is set on the product of the cross section for production via vector boson fusion and the branching fraction for such a Higgs boson decay, as a function of the Higgs boson mass. For a Higgs boson mass of 125 GeV, assuming the standard model production rates, the observed (expected) 95% confidence level upper limit on the branching fraction is 3.5 (2.8)%. This is the first search for such decays in the vector boson fusion channel. Combination with a previous search for Higgs bosons produced in association with a Z boson results in an observed (expected) upper limit on the branching fraction of 2.9 (2.1)% at 95% confidence level
Performance of the CMS muon trigger system in proton-proton collisions at âs = 13 TeV
- Author
- Aarrestad Thea Klaeboe
- Aarup Petersen Henriette
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdalla Hassan
- Abdelalim Ahmed Ali
- Abdullin Salavat
- Abercrombie Daniel
- Acharya Himal
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adamidis K.
- Adams Eric
- Adams Mark Raymond
- Adams Todd
- Addesa Francesca Maria
- Adloff Catherine
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agarwal Garvita
- Aggleton Robin
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmed Asar
- Ahuja Sudha
- Aime` Chiara
- Akchurin Nural
- Akgun Bora
- Akpinar Alp
- Albajar Carmen
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- AldĂĄ JĂșnior Walter Luiz
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Alison John
- Almond John
- Alvarez Gonzalez Barbara
- Alverson George
- Alves Gilvan
- Aly Reham
- Alyari Maral
- Amapane Nicola
- Ambrozas Marijus
- Amendola Chiara
- Amin Nick
- Amram Oz
- Amsler Claude
- Anagnostou Georgios
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Antchev Georgy
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apparu Dylan
- Appelt Eric
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Aruta Caterina
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asenov Patrick
- Asghar Muhammad Irfan
- Asilar Ece
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- Skinnari Louise
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- Smith Vincent J
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- WĂŒrthwein Frank
- Xiao Jie
- Xiao Meng
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- Yalvac Metin
- Yan Furong
- Yan Xuli
- Yang Unki
- Yang Yu Chul
- Yao Yao
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- Yates Brent
- Yazgan Efe
- Ye Zhenyu
- Yetkin Elif Asli
- Yi Kai
- Yigitbasi Efe
- Yohay Rachel
- Yoo Hwi Dong
- Yoo Jaehyeok
- Yoon Inseok
- You Zhengyun
- Yu David
- Yu Geum Bong
- Yu Intae
- Yu Pei-rong
- Yu Shin-Shan
- Yuan Li
- Yuan Siqi
- Yumiceva Francisco
- Yusli Mohd Nizam
- Zabi Alexandre
- Zabolotny Wojciech
- Zacharopoulou Anna
- Zahid Sema
- Zaleski Shawn
- Zalewski Piotr
- Zanetti Marco
- Zarubin Anatoli
- Zarucki Mateusz
- Zecchinelli Angelo Giacomo
- Zeinali Maryam
- Zenaiev Oleksandr
- Zeuner Wolfram Dietrich
- Zghiche Amina
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Sijing
- Zhang Wenyu
- Zhang Yi
- Zhang Zhicai
- Zhao Jingzhou
- Zhizhin Ilia
- Zhokin Alexander
- Zhu De Hua
- Zhu Ren-Yuan
- Ziemons Tim
- Zientek Margaret
- Zlebcik Radek
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Zygala Lara
- Ălvarez FernĂĄndez Adrian
- Ăzçelik Ăzlem
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2021
- Field of study
The muon trigger system of the CMS experiment uses a combination of hardware and software to identify events containing a muon. During Run 2 (covering 2015-2018) the LHC achieved instantaneous luminosities as high as 2 Ă 10 cm s while delivering proton-proton collisions at âs = 13 TeV. The challenge for the trigger system of the CMS experiment is to reduce the registered event rate from about 40 MHz to about 1 kHz. Significant improvements important for the success of the CMS physics program have been made to the muon trigger system via improved muon reconstruction and identification algorithms since the end of Run 1 and throughout the Run 2 data-taking period. The new algorithms maintain the acceptance of the muon triggers at the same or even lower rate throughout the data-taking period despite the increasing number of additional proton-proton interactions in each LHC bunch crossing. In this paper, the algorithms used in 2015 and 2016 and their improvements throughout 2017 and 2018 are described. Measurements of the CMS muon trigger performance for this data-taking period are presented, including efficiencies, transverse momentum resolution, trigger rates, and the purity of the selected muon sample. This paper focuses on the single- and double-muon triggers with the lowest sustainable transverse momentum thresholds used by CMS. The efficiency is measured in a transverse momentum range from 8 to several hundred GeV
Repositioning of the global epicentre of non-optimal cholesterol
- Author
- Aadahl Mette
- Abarca-GĂłmez Leandra
- Abu-Rmeileh Niveen M.
- Acosta-Cazares Benjamin
- Adams Robert J.
- Aekplakorn Wichai
- Agdeppa Imelda A.
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A.
- Agyemang Charles
- Ahluwalia Tarunveer S.
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmed Soheir H.
- Ahrens Wolfgang
- Ajlouni Kamel
- al-Safi Ismail Aziz
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M.
- Alkandari Abdullah
- Alkerwi Alaâa
- Aly Eman
- Amarapurkar Deepak N.
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A.
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Aounallah-Skhiri Hajer
- AraĂșjo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E.
- Arlappa Nimmathota
- Aryal Krishna K.
- Asghari Golaleh
- Aspelund Thor
- Assunção Maria CecĂlia F.
- Auvinen Juha
- AvdicovĂĄ MĂĄria
- Azevedo Ana
- Azizi Fereidoun
- Azmin Mehrdad
- Balakrishna Nagalla
- Bamoshmoosh Mohamed
- Banach Maciej
- Bandosz Piotr
- Banegas José R.
- Bao Tran Quoc
- Barbagallo Carlo M.
- BarcelĂł Alberto
- Barkat Amina
- Bata Iqbal
- Batieha Anwar M.
- Batyrbek Assembekov
- Baur Louise A.
- Beaglehole Robert
- Bebakar Wan Mohamad Wan
- Belavendra Antonisamy
- Ben Romdhane Habiba
- Benet Mikhail
- Benn Marianne
- Bennett James E.
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol Heloisa
- Bhargava Santosh K.
- Bi Yufang
- Bienek Asako
- Bikbov Mukharram
- Bista Bihungum
- Bixby Honor
- Bjerregaard Peter
- Bjertness Espen
- Bjertness Marius B.
- Björkelund Cecilia
- Bloch Katia V.
- Blokstra Anneke
- Bo Simona
- Boehm Bernhard O.
- Boggia Jose G.
- Boissonnet Carlos P.
- Bonaccio Marialaura
- Bongard Vanina
- Borchini Rossana
- Borghs Herman
- Bovet Pascal
- Brajkovich Imperia
- Breckenkamp Juergen
- Brenner Hermann
- Brewster Lizzy M.
- Bruno Graziella
- Bugge Anna
- Busch Markus A.
- Cacciottolo Joseph
- Can GĂŒnay
- Capanzana Mario V.
- Capuano Eduardo
- Capuano Vincenzo
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- Carvalho Joana
- Casanueva Felipe F.
- Censi Laura
- Chadjigeorgiou Charalambos A.
- Chamukuttan Snehalatha
- Chaturvedi Nish
- Chen Chien-Jen
- Chen Fangfang
- Chen Shuohua
- Cheng Ching-Yu
- Cheraghian Bahman
- Chetrit Angela
- Chiou Shu-Ti
- Chirlaque MarĂa-Dolores
- Cho Belong
- Cho Yumi
- Chudek Jerzy
- Cifkova Renata
- Cisneros Julio Zuñiga
- Claessens Frank
- Clarke Janine
- Clays Els
- Concin Hans
- Confortin Susana C.
- Cooper Cyrus
- Costanzo Simona
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- Crujeiras Ana B.
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- Dallongeville Jean
- Damasceno Albertino
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- Deepa Mohan
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- Delisle HĂ©lĂšne
- Dennison Elaine
- Deschamps Valérie
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- Djalalinia Shirin
- do Carmo Franco Maria
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- Eggertsen Robert
- Eghtesad Sareh
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- El Ati Jalila
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- Haghshenas Rosa
- Hakimi Hamid
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- Hantunen Sari
- Hashemi-Shahri Seyed Mohammad
- Hata Jun
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- Houti Leila
- Howitt Christina
- Htay Thein Thein
- Htet Aung Soe
- Htike Maung Maung Than
- Huerta JosĂ© MarĂa
- Huhtaniemi Ilpo Tapani
- Huisman Martijn
- Hunsberger Monica L.
- Husseini Abdullatif S.
- Huybrechts Inge
- Hwalla Nahla
- Iacoviello Licia
- Iannone Anna G.
- Ibrahim Mohsen M.
- Iglesia Iris
- Ikeda Nayu
- Ikram M. Arfan
- Iotova Violeta
- Irazola Vilma E.
- Ishida Takafumi
- Islam Muhammad
- Iurilli Maria Laura Caminia
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- Jackson Rod T.
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- Jamrozik Konrad
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- Jasienska Grazyna
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- Kelishadi Roya
- Kengne Andre Pascal
- Keramati Maryam
- Kerimkulova Alina
- Kersting Mathilde
- Khader Yousef Saleh
- Khalili Davood
- Khang Young-Ho
- Khateeb Mohammad
- Kheradmand Motahareh
- Khosravi Alireza
- Kiechl Stefan
- Kiechl-Kohlendorfer Ursula
- Killewo Japhet
- Kim Hyeon Chang
- Kim Jeongseon
- Kim Yeon-Yong
- Klumbiene Jurate
- Knoflach Michael
- Ko Stephanie
- Kohler Hans-Peter
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- Kolle Elin
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- Korpelainen Raija
- Korrovits Paul
- Kos Jelena
- Koskinen Seppo
- Kouda Katsuyasu
- Kowlessur Sudhir
- Kratzer Wolfgang
- Kriemler Susi
- Kristensen Peter Lund
- Krokstad Steiner
- Kromhout Daan
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- Kumar Rachakulla Hari
- Kurjata Pawel
- Kuulasmaa Kari
- Kyobutungi Catherine
- König JĂŒrgen
- Laamiri Fatima Zahra
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- Lachat Carl
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- Lambrinou Christina-Paulina
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- Latt Tint Swe
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- Lilly Christa L.
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- Parnell Winsome R.
- Patel Nikhil D.
- Peer Nasheeta
- Peixoto Sergio Viana
- Peltonen Markku
- Pereira Alexandre C.
- Peters Annette
- Petersmann Astrid
- Petkeviciene Janina
- Peykari Niloofar
- Pham Son Thai
- Pichardo Rafael N.
- Pigeot Iris
- Pilav Aida
- Pilotto Lorenza
- Piwonska Aleksandra
- Pizarro Andreia N.
- Plans-RubiĂł Pedro
- Plata Silvia
- Pohlabeln Hermann
- Porta Miquel
- Portegies Marileen L. P.
- Poudyal Anil
- Pourfarzi Farhad
- Poustchi Hossein
- Pradeepa Rajendra
- Price Jacqueline F.
- Providencia Rui
- Puder Jardena J.
- Puhakka Soile E.
- Punab Margus
- Qorbani Mostafa
- Radisauskas Ricardas
- Rahim Hanan Abdul
- Rahimikazerooni Salar
- Raitakari Olli
- Ramachandran Ambady
- Ramos Elisabete
- Ramos Rafel
- Rampal Lekhraj
- Rampal Sanjay
- Rao Kodavanti Mallikharjuna
- Rao Sudha Ramachandra
- Redon Josep
- Reganit Paul Ferdinand M.
- Revilla Luis
- Rezaianzadeh Abbas
- Ribeiro Robespierre
- Richter Adrian
- Rigo Fernando
- Riley Leanne M.
- Rinke de Wit Tobias F.
- RodrĂguez-Artalejo Fernando
- RodrĂguez-Villamizar Laura A.
- Roggenbuck Ulla
- Rojas-Martinez Rosalba
- Romaguera Dora
- Romeo Elisabetta L.
- Rosengren Annika
- Roy Joel G. R.
- Rubinstein Adolfo
- Ruidavets Jean-Bernard
- Ruiz-Betancourt Blanca Sandra
- Russo Paola
- Rust Petra
- Rutkowski Marcin
- Sabanayagam Charumathi
- Sachdev Harshpal S.
- Sadjadi Alireza
- Safarpour Ali Reza
- Safiri Saeid
- Saidi Olfa
- Saki Nader
- Salanave Benoit
- SalmerĂłn Diego
- Salomaa Veikko
- Salonen Jukka T.
- Salvetti Massimo
- Sans Susana
- Santaliestra-PasĂas Alba M.
- Santero Marilina
- Santos Diana A.
- Santos Maria Paula
- Santos Rute
- Saramies Jouko L.
- Sardinha Luis B.
- Sarrafzadegan Nizal
- Saum Kai-Uwe
- Savin Stefan
- Savva Savvas C.
- Sawada Norie
- Sbaraini Mariana
- Scazufca Marcia
- Schaan Beatriz D.
- Schargrodsky Herman
- Scheidt-Nave Christa
- Schienkiewitz Anja
- Schipf Sabine
- Schmidt Carsten O.
- Schramm Sara
- Schöttker Ben
- Sebert Sylvain
- Sein Aye Aye
- Sen Abhijit
- Sepanlou Sadaf G.
- Servais Jennifer
- Shakeri Ramin
- Shalnova Svetlana A.
- Shamah-Levy Teresa
- Sharafkhah Maryam
- Sharma Sanjib K.
- Shaw Jonathan E.
- Shayanrad Amaneh
- Shi Zumin
- Shibuya Kenji
- Shimizu-Furusawa Hana
- Shin Dong Wook
- Shin Youchan
- Shirani Majid
- Shiri Rahman
- Shrestha Namuna
- Si-Ramlee Khairil
- Siani Alfonso
- Siantar Rosalynn
- Sibai Abla M.
- Silva Diego Augusto Santos
- Simon Mary
- Simons Judith
- Simons Leon A.
- Sjöström Michael
- Skaaby Tea
- Slowikowska-Hilczer Jolanta
- Slusarczyk Przemyslaw
- Smeeth Liam
- Snijder Marieke B.
- Soemantri Agustinus
- Sofat Reecha
- Solfrizzi Vincenzo
- Somi Mohammad Hossein
- Sonestedt Emily
- Sophiea Marisa K.
- Soumaré Aïcha
- Sozmen Kaan
- Sparrenberger Karen
- Staessen Jan A.
- Stathopoulou Maria G.
- Stavreski Bill
- Steene-Johannessen Jostein
- Stehle Peter
- Stein Aryeh D.
- Stessman Jochanan
- StevanoviÄ Ranko
- Stevens Gretchen A.
- Stieber Jutta
- Stokwiszewski Jakub
- Stronks Karien
- Strufaldi Maria Wany
- Stöckl Doris
- Sun Chien-An
- Sundström Johan
- Suriyawongpaisal Paibul
- SuĂĄrez-Medina RamĂłn
- Sy Rody G.
- Sylva René Charles
- Szklo Moyses
- SĂĄnchez-Abanto Jose
- Söderberg Stefan
- SĂžrensen Thorkild I. A.
- Taddei Cristina
- Tai E. Shyong
- Tamosiunas Abdonas
- Tan Eng Joo
- Tarawneh Mohammed Rasoul
- Tarqui-Mamani Carolina B.
- Taylor Anne
- Taylor Julie
- Tell Grethe S.
- Tello Tania
- Thankappan K. R.
- Thijs Lutgarde
- Thuesen Betina H.
- Toft Ulla
- Tolonen Hanna K.
- Tolstrup Janne S.
- Topbas Murat
- TopĂłr-Madry Roman
- Tormo MarĂa JosĂ©
- Tornaritis Michael J.
- Torrent Maties
- Torres-Collado Laura
- Traissac Pierre
- Trinh Oanh T. H.
- Truthmann Julia
- Tsugane Shoichiro
- Tulloch-Reid Marshall K.
- Tuomainen Tomi-Pekka
- Tuomilehto Jaakko
- Tybjaerg-Hansen Anne
- Tzourio Christophe
- Ueda Peter
- Ugel Eunice
- Ulmer Hanno
- Unal Belgin
- Uusitalo Hannu M. T.
- Valdivia Gonzalo
- Valvi Damaskini
- van Dam Rob M.
- van der Schouw Yvonne T.
- Van Herck Koen
- Van Minh Hoang
- van Rossem Lenie
- Van Schoor Natasja M.
- van Valkengoed Irene G. M.
- Vanderschueren Dirk
- Vanuzzo Diego
- Varbo Anette
- Varona-PĂ©rez Patricia
- Vasan Senthil K.
- Vatten Lars
- Vega Tomas
- Veidebaum Toomas
- Velasquez-Melendez Gustavo
- Venero-FernĂĄndez Silvia J.
- Veronesi Giovanni
- Verschuren W. M. Monique
- Victora Cesar G.
- Vidiawati Dhanasari
- Viet Lucie
- Villalpando Salvador
- Vioque Jesus
- Virtanen Jyrki K.
- Visvikis-Siest Sophie
- Viswanathan Bharathi
- Vlasoff Tiina
- Vollenweider Peter
- Voortman Trudy
- Voutilainen Ari
- Vrkic Tajana Zeljkovic
- Wade Alisha N.
- Wagner Aline
- Walton Janette
- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S. Goya
- Wedderkopp Niels
- Wei Wenbin
- Whincup Peter H.
- Widhalm Kurt
- Widyahening Indah S.
- Wiecek Andrzej
- Wijga Alet H.
- Wilks Rainford J.
- Willeit Johann
- Willeit Peter
- Wilsgaard Tom
- Wojtyniak Bogdan
- Wong Andrew
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A.
- Woo Jean
- Woodward Mark
- Wu Frederick C.
- Wu Shouling
- Xu Haiquan
- Xu Liang
- Yan Weili
- Yang Xiaoguang
- Yasuharu Tabara
- Ye Xingwang
- Yeow Toh Peng
- Yiallouros Panayiotis K.
- Yoosefi Moein
- Yoshihara Akihiro
- You San-Lin
- Younger-Coleman Novie O.
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zainuddin Ahmad A.
- Zakavi Seyed Rasoul
- Zali Mohammad Reza
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Wenhua
- Zhen Shiqi
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhussupov Baurzhan
- Zoghlami Nada
- Publication venue
- Publication date
- 01/01/2020
- Field of study
High blood cholesterol is typically considered a feature of wealthy western countries(1,2). However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world(3) and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health(4,5). However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol-which is a marker of cardiovascular riskchanged from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million-4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world.Peer reviewe
Search for long-lived particles decaying to jets with displaced vertices in proton-proton collisions at root s=13 Te V
- Author
- Aarrestad Thea Klaeboe
- Aarup Petersen Henriette
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abercrombie Daniel
- Acharya Himal
- Acosta Darin
- Acosta John Gabriel
- Adam Wolfgang
- Adams Eric
- Adams Mark Raymond
- Adams Todd
- Addesa Francesca Maria
- Adloff Catherine
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agarwal Garvita
- Aggleton Robin
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmed Asar
- Ahuja Sudha
- Aime` Chiara
- Aimeâ C.
- Akchurin Nural
- Akgun Bora
- Akpinar Alp
- Albajar Carmen
- Albergo Sebastiano
- Albert Andreas
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- AldĂĄ JĂșnior Walter Luiz
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Alison John
- Almond John
- Alvarez Gonzalez Barbara
- Alverson George
- Alves Gilvan
- Aly Reham
- Alyari Maral
- Amapane Nicola
- Ambrozas Marijus
- Amendola Chiara
- Amin Nick
- Amram Oz
- Amsler Claude
- Anagnostou Georgios
- Andrea Jeremy
- Andreev Vladimir
- Andreev Yu.
- Andreev Yuri
- Andrews Michael Benjamin
- Androsov Konstantin
- Antchev Georgy
- Antunovic Zeljko
- Apanasevich Leonard
- Apollinari Giorgio
- Apparu Dylan
- Appelt Eric
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Aruta Caterina
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asenov Patrick
- Asghar Muhammad Irfan
- Asilar Ece
- Askew Andrew
- Asmuss Paul
- Atakisi Ismail Okan
- Atanasov Ivan
- Ather Mohsan Waseem
- Attikis Alexandros
- Auffray Etiennette
- Aushev Tagir
- Auzinger Georg
- Avati Valentina
- Avery Paul
- Avila Carlos
- Awais Ali
- Awan Muhammad Imran Malik
- Ayala Edy
- Ayala Gabriel
- Aydogmus Sen Fatma
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzurri Paolo
- Baarmand Marc M.
- Babaev Anton
- Babounikau Illia
- Bacchetta Nicola
- Bachiller Irene
- Bachtis Michail
- Backhaus Malte
- Baden A.
- Baden Drew
- Baechler Joachim
- Bagliesi Giuseppe
- Bahinipati Seema
- Baillon Paul
- Bainbridge Robert
- Bakas Georgios
- Bakhshiansohi Hamed
- Bakirci Mustafa Numan
- Bakshi Amandeep Singh
- Baldenegro Barrera Cristian
- Ball Austin
- Ban Yong
- Band Reyer
- Bandyopadhyay Hirak
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Bargassa Pedrame
- Baringer Philip
- Barnes Virgil E.
- Barney David
- Baron Owen
- Barrio Luna Mar
- Bartek Rachel
- Bartosik Nazar
- BartĂłk MĂĄrton
- Bastos Diogo
- Battilana Carlo
- Baty Austin
- Bauer Gerry
- Bauerdick Lothar A. T.
- Baxter Samuel
- Bayshev Igor
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Becerril Gonzalez Hugo
- Bechtel Janek
- Beghin Diego
- Behera Prafulla Kumar
- Behera Subash Chandra
- Behnke Olaf
- Bein Samuel
- Belchior Batista Das Chagas Ewerton
- Belforte Stefano
- Bell Ken W.
- Bellan Riccardo
- Belloni Alberto
- Bellora Andrea
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
- Benato Lisa
- Bencze Gyorgy
- Bendavid Joshua
- Benecke Anna
- Benelli Gabriele
- Beni Noemi
- Benitez Jose F.
- Benussi Luigi
- Berenguer Antequera Jorge
- Beretvas Andrew
- Bergauer Thomas
- Berger Pirmin
- Berger Thomas
- Beri Suman Bala
- BermĂșdez MartĂnez Armando
- Bernardes Cesar Augusto
- Bernet Colin
- Berry Douglas
- Berryhill Jeffrey
- Bertacchi Valerio
- Besancon Marc
- Beschi Andrea
- Bethani Agni
- Bhal Eshwen
- Bhardwaj Ashutosh
- Bharti Monika
- Bhat Pushpalatha C.
- Bhatnagar Vipin
- Bhattacharya Rajarshi
- Bhattacharya Saptaparna
- Bhattacharya Satyaki
- Bhattacharya Soham
- Bheesette Srinidhi
- Bhowmik Debabrata
- Bhowmik Sandeep
- Bhyun Ji Hwan
- Bi Ran
- Bialkowska Helena
- Bianchini Lorenzo
- Bianco Michele
- Bianco Stefano
- Biino Cristina
- Bilei Gian Mario
- Bilin Bugra
- Bin Anuar Afiq Aizuddin
- Bisello Dario
- Black Kevin
- Blekman Freya
- Blinov Vladimir
- Bloch Daniel
- Bloch Philippe
- Bloom Kenneth
- Bluj Michal
- Blumenfeld Barry
- Boccali Tommaso
- Bocci Andrea
- Bodek Arie
- Boimska Bozena
- Boletti Alessio
- Bologna Simone
- Bols Emil SĂžrensen
- Bonacorsi Daniele
- Bonanomi Matteo
- Bonham Brandon
- Bonomally Shameena
- Boos Edouard
- Boran Fatma
- Borchsh V.
- Borg Johan
- Borgonovi Lisa
- Bornheim Adolf
- Borras Kerstin
- Borshch Vladislav
- Bortignon Pierluigi
- Bose Tulika
- Bossini Edoardo
- Botta Cristina
- Botta Valeria
- Boudoul Gaelle
- Bouhali Othmane
- Bourgatte Guillaume
- Bourilkov Dimitri
- Bozzo Marco
- Bragagnolo Alberto
- Braghieri Alessandro
- Braibant-Giacomelli Sylvie
- Brainerd Christopher
- Brandao Malbouisson Helena
- Brandt Stephanie
- Branson James G.
- Breedon Richard
- Breeze Shane
- Brew Christopher
- Brigljevic Vuko
- Brinkerhoff Andrew
- Brivio Francesco
- Brochero Cifuentes Javier Andres
- Brom Jean-Marie
- Brondolin Erica
- Brooke James John
- Brown Robert M.
- Brunner David
- Bruno Giacomo
- Bryson Miranda
- Brzhechko Danyyl
- BrĂŒcken Erik
- Bucci Rachael
- Buccilli Andrew
- Buchanan James
- Buchmuller Oliver
- Buchot Perraguin Axel
- Budkouski Dzmitry
- Bueghly James
- Bundock Aaron
- Bunichev Viacheslav
- Bunin Pavel
- Bunkowski Karol
- Buontempo Salvatore
- Burkett Kevin
- Burkle Bjorn
- Burt Kira
- Bury Florian Joel J.
- Busson Philippe
- Busza Wit
- Butalla Stephen
- Butler Joel Nathan
- Butler Philip H.
- Butz Erik
- Bychkova Oksana
- Bylinkin Alexander
- Bylsma Ben
- Cabrera Andrés
- Cabrillo Iban Jose
- Cadamuro Luca
- Caillol CĂ©cile
- Cakir Altan
- Calandri Alessandro
- Calderon De La Barca Sanchez Manuel
- Calderon Alicia
- Cali Ivan Amos
- Calligaris Luigi
- Calzaferri Simone
- Camen Camille
- Caminada Lea
- Campagnari Claudio
- Campanini Renato
- Campbell Alan
- Camporesi Tiziano
- Candelise Vieri
- Canelli Maria Florencia
- Canepa Anadi
- Cankocak Kerem
- Capeans Garrido Maria
- Capiluppi Paolo
- Cappati Alessandra
- Caputo Claudio
- Caraway Bryan
- Cardini Andrea
- Cardwell Bryan
- Carle Aurélien
- Carlin Roberto
- Carrera Jarrin Edgar
- Carrillo Montoya Camilo Andres
- Carrillo Moreno Salvador
- Cartiglia Nicolo
- Carvalho Antunes De Oliveira Alexandra
- Carvalho Wagner
- Casarsa Massimo
- Caspart René
- Cassese Antonio
- Castaldi Rino
- Castaneda Hernandez Alfredo
- Castilla-Valdez Heriberto
- Castro Andrea
- Cavallari Francesca
- Cavallo Francesca Romana
- Cavallo Nicola
- Cavanaugh Richard
- Ceard Ludivine
- Ceccarelli Rudy
- Cepaitis Vilius
- Cepeda Maria
- Cerati Giuseppe Benedetto
- Cerci Salim
- Cerminara Gianluca
- Cerrada Marcos
- Cerri Olmo
- Cetorelli Flavia
- Chabert Eric Christian
- Chadeeva Marina
- Chahal Gurpreet Singh
- Chang Paoti
- Chang Philip
- Chanon Nicolas
- Chao Yuan
- Chapon Emilien
- Charaf Otman
- Charlot Claude
- Chatterjee Rajdeep Mohan
- Chatterjee Suman
- Chaudhary Geetanjali
- Chauhan Shubhanshu
- Chauhan Sushil
- Chawla Ridhi
- Chazin Quero Barbara
- Checchia Paolo
- Chekhovsky Vladimir
- Chen Cheng
- Chen Guo-Ming
- Chen He-Sheng
- Chen Kai-Feng
- Chen Mingshui
- Chen Po-Hsun
- Chen Xuan
- Chen Yi
- Chen Yuan
- Chen Ziheng
- Chenarani Shirin
- Cheng Tongguang
- Cheng Yangyang
- Cherepanov Vladimir
- Chernyavskaya Nadezda
- Chertok Maxwell
- Cheung H. W. K.
- Chhibra Simranjit Singh
- Chiarito Brandon
- Chinellato Jose
- Chlebana Frank
- Cho Sungwoong
- Choi Junho
- Choi Suyong
- Choi Young-Il
- Chou John Paul
- Choudhary Brajesh C.
- Choudhury Somnath
- Chu Jennifer
- Chudasama Ruchi
- Chwalek Thorsten
- Ciangottini Diego
- Ciocca Claudia
- Ciocci Maria Agnese
- Cipriani Marco
- Ciriolo Vincenzo
- Citron Matthew
- Cittolin Sergio
- Ciulli Vitaliano
- Civinini Carlo
- Claes Daniel R.
- Clare Robert
- Clement Emyr
- Clerbaux Barbara
- CMS Collaboration
- Cockerill David J. A.
- Coelho Eduardo
- Colaleo Anna
- Cole Joanne
- Colino Nicanor
- Collard Caroline
- Colling David
- Cometti Simona
- Connor Patrick
- Consuegra RodrĂguez Sandra
- Contardo Didier
- Conway John
- Conway Rylan
- Cooper Seth
- Cooperstein Stephane
- Corcodilos Lucas
- Cornelis Tom
- Cosby Christopher
- Cossutti Fabio
- Costa Marco
- Costa Salvatore
- Coubez Xavier
- Couderc Fabrice
- Cousins Robert
- Covarelli Roberto
- Cox Bradley
- Cox Peter Timothy
- Cranshaw Derek James
- Creanza Donato
- Cremonesi Matteo
- Cristella Leonardo
- Csanad Mate
- Csorgo Tamas Ferenc
- Cuevas Javier
- Cuffiani Marco
- Cumalat John Perry
- Cummings Grace
- Cussans David
- Cutts David
- Czellar Sandor
- D'Alessandro Raffaello
- D'Alfonso Mariarosaria
- D'Enterria David
- D'Hondt Jorgen
- Da Rold Alessandro
- Da Silveira Gustavo Gil
- Dabrowski Anne
- Daci Nadir
- Dalchenko Mykhailo
- Dallavalle Gaetano-Marco
- Damarseckin Serdal
- Damgov Jordan
- Danilov Vladyslav
- Darej Douja
- Darwish Mohamed Rashad
- Das Pallabi
- Das Souvik
- Dasgupta Abhigyan
- Dash Dipika
- Daskalakis Georgios
- Dasu Sridhara
- Datta Abhisek
- Dauncey Paul
- David Tinoco Mendes Andre
- David Pieter
- Davies Gavin
- Davignon Olivier
- de Barbaro Pawel
- De Boer Wim
- De Bruyn Isabelle
- De Castro Manzano Pablo
- De Clercq Jarne
- De Cosa Annapaola
- De Filippis Nicola
- De Guio Federico
- De Iorio Agostino
- De Jesus Damiao Dilson
- De La Cruz Begona
- De La Cruz-Burelo Eduard
- De Lentdecker Gilles
- De Leo Ksenia
- De Moraes Gregores Eduardo
- De Palma Mauro
- De Roeck Albert
- De Souza Lemos Dener
- de TrocĂłniz Jorge F.
- De Wit Adinda
- De Wolf Eddi A.
- Deelen Nikkie
- Defranchis Matteo Maria
- Deile Mario
- Dejardin Marc
- Del Burgo Riccardo
- Del Re Daniele
- Delaere Christophe
- Delannoy Andrés G.
- Delcourt Martin
- Delgado Peris Antonio
- Delgado Andrea
- Dell'Orso Roberto
- Della Negra Michel
- Della Ricca Giuseppe
- Demaria Natale
- Demina Regina
- Demiragli Zeynep
- Demiroglu Zuhal Seyma
- Denegri Daniel
- Depasse Pierre
- Dermenev Alexander
- Dev Nabarun
- Dewanjee Ram Krishna
- Dezoort Gage
- Dhammage Deshitha Chamikara Wickramarathna
- Dharmaratna Welathantri G. D.
- Dhingra Nitish
- Di Croce Davide
- Di Domenico Maria Rosaria
- Di Florio Adriano
- Di Marco Emanuele
- Di Maria Riccardo
- Di Mattia Alessandro
- Di Petrillo Karri Folan
- Di Pilato Antonio
- Diab Batoul
- Diamantopoulou Magda
- Diaz Daniel
- Didukh Leonid
- Diemoz Marcella
- Dierlamm Alexander
- Dildick Sven
- Dilsiz Kamuran
- Dimitrov Anton
- Dimova Tatyana
- Dinardo Mauro Emanuele
- Dini Paolo
- Diotalevi Tommaso
- Dissertori GĂŒnther
- Dittmann Jay
- Dittmar Michael
- Dittmer Susan
- Dobson Marc
- Dobur Didar
- Dogra Sunil
- Dolek Furkan
- Dolen James
- Dominguez Aaron
- DomĂnguez Damiani Daniela
- Donato Silvio
- DonegĂ Mauro
- Donertas Izzeddin Suat
- Dordevic Milos
- Dorfer Christian
- Dorigo Tommaso
- Dorney Brian
- Doroba Krzysztof
- Dorsett Alex
- Dozen Candan
- Dragicevic Marko
- Dremin Igor
- Dreyer Torben
- Droll Alexander
- Duarte Campderros Jordi
- Duarte Javier
- Dube Sourabh
- Dubinin Mikhail
- Dudko Lev
- Dugad Shashikant
- Duh Yi-ting
- Dulemba Joseph Lynn
- Dumanoglu Isa
- Dupont-Sagorin Niels
- Durgut SĂŒleyman
- Duric Senka
- Durkin Lloyd Stanley
- Dutta Dipanwita
- Dutta Irene
- Dutta Suchandra
- Dutta Valentina
- Dziwok Christian
- DĂŒnser Marc
- Ebrahimi Aliakbar
- Eckerlin Guenter
- Ecklund Karl Matthew
- Eckstein Doris
- Eerola Paula
- Ehataht Karl
- Eich Melanie
- El Mamouni Houmani
- El Morabit Karim
- Elgammal Sherif
- Eliseev Dmitry
- Elkafrawy Tamer
- Elliott-Peisert Anna
- Ellis Katherine Victoria
- Ellithi Kamel Ali
- Elmer Peter
- Elmetenawee Walaa
- Elvira Victor Daniel
- Eminizer Margaret
- Emriskova Natalia
- Eno Sarah Catherine
- Epshteyn Vladimir
- Erbacher Robin
- Erdmann Martin
- Erdmann Wolfram
- Erice Carlos
- Erodotou Eleni
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- Ye Zhenyu
- Yetkin Elif Asli
- Yi Kai
- Yigitbasi Efe
- Yohay Rachel
- Yoo Hwi Dong
- Yoo Jaehyeok
- Yoon Inseok
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- Yuan Li
- Yuan Siqi
- Yumiceva Francisco
- Yusli Mohd Nizam
- Zabi Alexandre
- Zacharopoulou Anna
- Zahid Sema
- Zaleski Shawn
- Zalewski Piotr
- Zanetti Marco
- Zarubin Anatoli
- Zarucki Mateusz
- Zecchinelli Angelo Giacomo
- Zeinali Maryam
- Zenaiev Oleksandr
- Zeuner Wolfram Dietrich
- Zghiche Amina
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Sijing
- Zhang Wenyu
- Zhang Yi
- Zhang Zhicai
- Zhao Jingzhou
- Zhizhin Ilia
- Zhokin Alexander
- Zhu De Hua
- Zhu Ren-Yuan
- Ziemons Tim Matthias
- Zientek Margaret
- Zlebcik Radek
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Zygala Lara
- Ălvarez FernĂĄndez Adrian
- Ăzçelik Ăzlem
- Publication venue
- Publication date
- 01/01/2021
- Field of study
A search is presented for long-lived particles produced in pairs in proton-proton collisions at the LHC operating at a center-of-mass energy of 13 TeV. The data were collected with the CMS detector during the period from 2015 through 2018, and correspond to a total integrated luminosity of 140 fb(-1). This search targets pairs of long-lived particles with mean proper decay lengths between 0.1 and 100 mm, each of which decays into at least two quarks that hadronize to jets, resulting in a final state with two displaced vertices. No significant excess of events with two displaced vertices is observed. In the context of R-parity violating supersymmetry models, the pair production of long-lived neutralinos, gluinos, and top squarks is excluded at 95% confidence level for cross sections larger than 0.08 fb, masses between 800 and 3000 GeV, and mean proper decay lengths between 1 and 25 mm.Peer reviewe
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