42 research outputs found

    Shrinking a large dataset to identify variables associated with increased risk of Plasmodium falciparum infection in Western Kenya

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    Large datasets are often not amenable to analysis using traditional single-step approaches. Here, our general objective was to apply imputation techniques, principal component analysis (PCA), elastic net and generalized linear models to a large dataset in a systematic approach to extract the most meaningful predictors for a health outcome. We extracted predictors for Plasmodium falciparum infection, from a large covariate dataset while facing limited numbers of observations, using data from the People, Animals, and their Zoonoses (PAZ) project to demonstrate these techniques: data collected from 415 homesteads in western Kenya, contained over 1500 variables that describe the health, environment, and social factors of the humans, livestock, and the homesteads in which they reside. The wide, sparse dataset was simplified to 42 predictors of P. falciparum malaria infection and wealth rankings were produced for all homesteads. The 42 predictors make biological sense and are supported by previous studies. This systematic data-mining approach we used would make many large datasets more manageable and informative for decision-making processes and health policy prioritization

    Measurement of the Bottom-Strange Meson Mixing Phase in the Full CDF Data Set

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    We report a measurement of the bottom-strange meson mixing phase \beta_s using the time evolution of B0_s -> J/\psi (->\mu+\mu-) \phi (-> K+ K-) decays in which the quark-flavor content of the bottom-strange meson is identified at production. This measurement uses the full data set of proton-antiproton collisions at sqrt(s)= 1.96 TeV collected by the Collider Detector experiment at the Fermilab Tevatron, corresponding to 9.6 fb-1 of integrated luminosity. We report confidence regions in the two-dimensional space of \beta_s and the B0_s decay-width difference \Delta\Gamma_s, and measure \beta_s in [-\pi/2, -1.51] U [-0.06, 0.30] U [1.26, \pi/2] at the 68% confidence level, in agreement with the standard model expectation. Assuming the standard model value of \beta_s, we also determine \Delta\Gamma_s = 0.068 +- 0.026 (stat) +- 0.009 (syst) ps-1 and the mean B0_s lifetime, \tau_s = 1.528 +- 0.019 (stat) +- 0.009 (syst) ps, which are consistent and competitive with determinations by other experiments.Comment: 8 pages, 2 figures, Phys. Rev. Lett 109, 171802 (2012

    W boson polarization measurement in the ttbar dilepton channel using the CDF II Detector

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    We present a measurement of WW boson polarization in top-quark decays in ttˉt\bar{t} events with decays to dilepton final states using 5.1fb−15.1 {\rm fb^{-1}} of integrated luminosity in ppˉp\bar{p} collisions collected by the CDF II detector at the Tevatron. A simultaneous measurement of the fractions of longitudinal (f0f_0) and right-handed (f+f_+) WW bosons yields the results f0=0.71−0.17+0.18(stat)±0.06(syst)f_0 = 0.71 ^{+0.18}_{-0.17} {\rm (stat)} \pm 0.06 {\rm (syst)} and f+=−0.07±0.09(stat)±0.03(syst)f_+ = -0.07 \pm 0.09 {\rm (stat)} \pm 0.03 {\rm (syst)}. Combining this measurement with our previous result based on single lepton final states, we obtain f0=0.84±0.09(stat)±0.05(syst)f_0 = 0.84 \pm 0.09 {\rm (stat)} \pm 0.05 {\rm (syst)} and f+=−0.16±0.05(stat)±0.04(syst)f_{+} = -0.16 \pm 0.05 {\rm (stat)} \pm 0.04 {\rm (syst)}. The results are consistent with standard model expectation.Comment: Published in Phys. Lett.

    Measurement of the Bs Lifetime in Fully and Partially Reconstructed Bs -> Ds- (phi pi-)X Decays in pbar-p Collisions at sqrt(s) = 1.96 TeV

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    We present a measurement of the Bs lifetime in fully and partially reconstructed Bs -> Ds(phi pi)X decays in 1.3 fb-1 of pbar-p collisions at sqrt(s) = 1.96 TeV collected by the CDF II detector at the Fermilab Tevatron. We measure tau(Bs) = 1.518 +/- 0.041 (stat.) +/- 0.027 (syst.) ps. The ratio of this result and the world average B0 lifetime yields tau(Bs)/tau(B0) = 0.99 +/-0.03, which is in agreement with recent theoretical predictions.Comment: submitted to Phys. Rev. Let

    Observation of the Y(4140)Y(4140) structure in the J/ψ ϕJ/\psi\,\phi Mass Spectrum in B±→J/ψ ϕKB^\pm\to J/\psi\,\phi K cays

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    The observation of the Y(4140)Y(4140) structure in B±→J/ψ ϕK±B^\pm\rightarrow J/\psi\,\phi K^\pm decays produced in pˉp\bar{p} p collisions at \sqrt{s}=1.96~\TeV is reported with a statistical significance greater than 5 standard deviations. A fit to the J/ψ ϕJ/\psi\,\phi mass spectrum is performed assuming the presence of a Breit-Wigner resonance. The fit yields a signal of 19−5+619^{+6}_{-5} resonance events, and resonance mass and width of 4143.4^{+2.9}_{-3.0}(\mathrm{stat})\pm0.6(\mathrm{syst})~\MeVcc and 15.3^{+10.4}_{-6.1}(\mathrm{stat})\pm2.5(\mathrm{syst})~\MeVcc respectively. The parameters of this resonance-like structure are consistent with values reported from an earlier CDF analysis.Comment: 7 pages, 2 figures, submited to Phys. Rev. Let

    Production of K0S, K*±(892) and ϕ0(1020) in minimum bias events and K0S and Λ0 in jets in ppÂŻ collisions at s√=1.96  TeV

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    We report measurements of the inclusive transverse momentum (pT) distribution of centrally produced K0S, K⋆±(892), and ϕ0(1020) mesons up to pT=10  GeV/c in minimum bias events, and K0S and Λ0 particles up to pT=20  GeV/c in jets with transverse energy between 25 and 160 GeV in ppÂŻ collisions. The data were taken with the CDF II detector at the Fermilab Tevatron at s√=1.96  TeV. We find that as pT increases, the pT slopes of the three mesons (K0S, K⋆±, and ϕ) are similar. And using our previous Λ0 results from minimum bias events, we show that the ratio of Λ0 to K0S as a function of pT in minimum bias events becomes similar to the fairly constant ratio in jets at pT∌5  GeV/c. This suggests that the particles with pT≳5  GeV/c in minimum bias events are from “soft” jets, and that the pT slope of particles in jets is insensitive to light quark flavor (u, d, or s) and to the number of valence quarks. We also find that for pTâ‰Č4  GeV relatively more Λ0 baryons are produced in minimum bias events than in jets

    Microspheres for Drug Delivery

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