An Evaluation on Electronic Patient-Reported Outcomes in Ciparay Sub-District, Bandung, West Java

Electronic Patient-Reported Outcomes for children has become more common as a means to collect health data during conception, pregnancy, and childbirth. However, it remains unclear whether the responsive level of the digital divide on the technology. The purpose of this study was to assess the adoption of an Electronic Patient-Reported Outcomes by mothers to monitor the health status of their infants in Ciparay Sub-District, West Java Province. This study also examined the relationship between demographic characteristics on the utilization of the new technology and perceived barriers for usage. A total of 112 patients had registered into an Electronic Patient-Reported Outcomes entitled ‘Memobayi’ from April to July 2016. Personal and technical factors affectedthe adoption of electronic technology for recording the health status of their infants. This included lack of knowledge, privacy as well as technical concerns. The result of the study also revealed that although the use of information and communication technologies in Indonesia had overgrown during the last ten years, a considerable gap remained between those with and without access to the adoption of Electronic Patient-Reported Outcomes. Keywords: Electronic Patient-Reported Outcomes, Digital Divide, Memobayi, Ciparay

Analysis of Citizen Relationship Management (CRM) in the effort of Handling Public Facilities Infrastructure (PPSU) in the Kartini’ Sub District , Central Jakarta

Citizen Relationship Management Mobile is an application that is created to be able to follow up on all complaints that have been reported by Jakarta's residents so that local governments of DKI can coordinate faster in resolving complaints of Jakarta’s society. Kartini sub-district applies a CRM application in handling public complaints regarding the handling of public facilities infrastructure (PPSU). Through the CRM application, PPSU of Kartini sub-district workers can find community reports, not only locations or pictures of the actual condition of reported public facilities but also their identities so that public's complaints can be resolved quickly. However, what often happens is that reports submitted by the society through pictures (photos) are not suitable with the actual situation, the address is not clear as well and also it does not include the identity of the reporter. This makes it difficult for PPSU of Kartini sub-district workers to follow up. Another problem faced is that several complaints reports do not include the main duties and functions of PPSU workers. The method used in this research is a descriptive qualitative approach to collect information about real current conditions. Interviews were conducted with 8 informants. The results showed that the application of CRM in the Kartini’s sub-district was quite effective, as indicated by the level of reports/complaints related to the handling of public facilities submitted by the residents, which decreased significantly, although there were still obstacles faced so that the implementation of CRM ran optimally. Various efforts have been made by the Kartini sub-district to overcome these obstacles so that the follow-up of reports/complaints from the public regarding public facilities infrastructure has higher quality, faster, more precise, and accurate

Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Dimethyl fumarate (DMF) inhibits inflammasome-mediated inflammation and has been proposed as a treatment for patients hospitalised with COVID-19. This randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple treatments in patients hospitalised for COVID-19 (NCT04381936, ISRCTN50189673). In this assessment of DMF performed at 27 UK hospitals, adults were randomly allocated (1:1) to either usual standard of care alone or usual standard of care plus DMF. The primary outcome was clinical status on day 5 measured on a seven-point ordinal scale. Secondary outcomes were time to sustained improvement in clinical status, time to discharge, day 5 peripheral blood oxygenation, day 5 C-reactive protein, and improvement in day 10 clinical status. Between 2 March 2021 and 18 November 2021, 713 patients were enroled in the DMF evaluation, of whom 356 were randomly allocated to receive usual care plus DMF, and 357 to usual care alone. 95% of patients received corticosteroids as part of routine care. There was no evidence of a beneficial effect of DMF on clinical status at day 5 (common odds ratio of unfavourable outcome 1.12; 95% CI 0.86-1.47; p = 0.40). There was no significant effect of DMF on any secondary outcome

Telomerase Inhibitor: Promising Target Therapy for Cancer

The key to selectively targeting cancer cells is to exploit some basic differences with their normal precursors. One such difference is the activity of the enzyme telomerase. Some studies targeted telomerase and telomeres in order to block limitless replicative potential of cancer cells, providing a Fascinating strategy for a broad-spectrum cancer therapy. Telomerase based therapies could be well tolerated and perhaps with minimal side effect on telomerase-competent stem cells.Kunci pengobatan selektif sel kanker adalah dengan memanfaatkan beberapa perbedaan mendasar antara prekursor sel kanker dengan sel normal tubuh. Salah satu perbedaannya adalah aktivitas enzim telomerase. Beberapa penelitian sudah menargetkan telomerase dan telomer sebagai target terapeutik untuk memblokir potensi replikasi sel kanker yang tak terbatas, sebagai strategi terapi kanker spektrum luas. Terapi berbasis telomerase ini dapat ditoleransi dengan baik dan memiliki efek samping minimal pada telomerase sel normal tubuh lainnya

Critical Analysis of Consumer Protection in “Lootbox” Virtual Transaction System in Indonesia

Purpose of this research is to determine consumer protection regulation for virtual (Lootbox) transactions in Indonesia. The research method is normative legal studies. Results of the study is that virtual transactions are easily carried out, such as loot box virtual transactions that is affected to financial loss for both consumers and countries. Regulations that have made by several countries need to be further analyzed and examined in order to be implemented and regulated as in the country of Belgium issuing rules that require the (Lootbox) to be banned or be subjected to sanctions for violations of the Gambling Law in that country. So that Indonesia should make (Lootbox) regulation even though the regulation is unspecified in KUHP and Bill of Act on Electronic Information and Transaction that can make consumers protection is more guaranteed

Thigh-length compression stockings and DVT after stroke

Controversy exists as to whether neoadjuvant chemotherapy improves survival in patients with invasive bladder cancer, despite randomised controlled trials of more than 3000 patients. We undertook a systematic review and meta-analysis to assess the effect of such treatment on survival in patients with this disease