26 research outputs found
The ATLAS fast tracKer system
- Author
- Aad G.
- Abbott B.
- Abbott D. C.
- Abed Abud A.
- Abeling K.
- Abhayasinghe D. K.
- Abidi S. H.
- AbouZeid O. S.
- Abraham N. L.
- Abramowicz H.
- Abreu H.
- Abulaiti Y.
- Acharya B. S.
- Achkar B.
- Adam Bourdarios C.
- Adam L.
- Adamczyk L.
- Adamek L.
- Adelman J.
- Adiguzel A.
- Adorni S.
- Adye T.
- Affolder A. A.
- Afik Y.
- Agapopoulou C.
- Agaras M. N.
- Aggarwal A.
- Agheorghiesei C.
- Aguilar-Saavedra J. A.
- Ahmad A.
- Ahmadov F.
- Ahmed W. S.
- Ai X.
- Aielli G.
- Akatsuka S.
- Akbiyik M.
- Akilli E.
- Akimov A. V.
- Al Khoury K.
- Alberghi G. L.
- Albert J.
- Albicocco P.
- Alconada Verzini M. J.
- Alderweireldt S.
- Aleksa M.
- Aleksandrov I. N.
- Alexa C.
- Alexopoulos T.
- Alfonsi A.
- Alfonsi F.
- Alhroob M.
- Ali B.
- Ali S.
- Aliev M.
- Alimonti G.
- Alison J.
- Allaire C.
- Allbrooke B. M. M.
- Allport P. P.
- Aloisio A.
- Alonso F.
- Alpigiani C.
- Alunno Camelia E.
- Alvarez Estevez M.
- Alviggi M. G.
- Amaral Coutinho Y.
- Ambler A.
- Ambroz L.
- Amelung C.
- Amidei D.
- Amor Dos Santos S. P.
- Amoroso S.
- Amrouche C. S.
- Anastopoulos C.
- Andari N.
- Andeen T.
- Anders J. K.
- Anderson J. T.
- Andrean S. Y.
- Andreazza A.
- Andrei V.
- Anelli C. R.
- Angelidakis S.
- Angerami A.
- Anisenkov A. V.
- Annovi A.
- Antel C.
- Anthony M. T.
- Antipov E.
- Antonelli M.
- Antrim D. J. A.
- Anulli F.
- Aoki M.
- Aparisi Pozo J. A.
- Aparo M. A.
- Aperio Bella L.
- Aranzabal N.
- Araujo Ferraz V.
- Araujo Pereira R.
- Arcangeletti C.
- Arce A. T. H.
- Arguin J-F.
- Argyropoulos S.
- Arling J. -H.
- Armbruster A. J.
- Armstrong A.
- Arnaez O.
- Arnold H.
- Arrubarrena Tame Z. P.
- Artoni G.
- Asada H.
- Asai K.
- Asai S.
- Asawatavonvanich T.
- Asbah N.
- Asimakopoulou E. M.
- Asquith L.
- Assahsah J.
- Assamagan K.
- Astalos R.
- Atkin R. J.
- Atkinson M.
- Atlay N. B.
- Atmani H.
- Atmasiddha P. A.
- Augsten K.
- Austrup V. A.
- Avolio G.
- Ayoub M. K.
- Azuelos G.
- Babal D.
- Bachacou H.
- Bachas K.
- Backman F.
- Bagnaia P.
- Bahmani M.
- Bahrasemani H.
- Bailey A. J.
- Bailey V. R.
- Baines J. T.
- Bakalis C.
- Baker O. K.
- Bakker P. J.
- Bakos E.
- Bakshi Gupta D.
- Balaji S.
- Balasubramanian R.
- Baldin E. M.
- Balek P.
- Balli F.
- Balunas W. K.
- Balz J.
- Banas E.
- Bandieramonte M.
- Bandyopadhyay A.
- Barak L.
- Barbe W. M.
- Barberio E. L.
- Barberis D.
- Barbero M.
- Barbour G.
- Barillari T.
- Barisits M-S.
- Barkeloo J.
- Barklow T.
- Barnett B. M.
- Barnett R. M.
- Barnovska-Blenessy Z.
- Baroncelli A.
- Barone G.
- Barr A. J.
- Barranco Navarro L.
- Barreiro Guimarães da Costa J.
- Barreiro F.
- Barron U.
- Barsov S.
- Bartels F.
- Bartoldus R.
- Bartolini G.
- Barton A. E.
- Bartos P.
- Basalaev A.
- Basan A.
- Bassalat A.
- Basso M. J.
- Basson C. R.
- Bates R. L.
- Batlamous S.
- Batley J. R.
- Batool B.
- Battaglia M.
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- Bauer F.
- Bauer P.
- Bawa H. S.
- Bayirli A.
- Beacham J. B.
- Beau T.
- Beauchemin P. H.
- Becherer F.
- Bechtle P.
- Beck H. P.
- Becker K.
- Becot C.
- Beddall A.
- Beddall A. J.
- Bednyakov V. A.
- Bee C. P.
- Beermann T. A.
- Begalli M.
- Begel M.
- Behera A.
- Behr J. K.
- Beisiegel F.
- Belfkir M.
- Bella G.
- Bellagamba L.
- Bellerive A.
- Bellos P.
- Beloborodov K.
- Belotskiy K.
- Belyaev N. L.
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- Benekos N.
- Benhammou Y.
- Benjamin D. P.
- Benoit M.
- Bensinger J. R.
- Bentvelsen S.
- Beresford L.
- Beretta M.
- Berge D.
- Bergeaas Kuutmann E.
- Berger N.
- Bergmann B.
- Bergsten L. J.
- Beringer J.
- Berlendis S.
- Bernardi G.
- Bernius C.
- Bernlochner F. U.
- Berry T.
- Berta P.
- Berthold A.
- Bertram I. A.
- Bessidskaia Bylund O.
- Bethke S.
- Betti A.
- Bevan A. J.
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- Bhattacharya D. S.
- Bhattarai P.
- Bhopatkar V. S.
- Bi R.
- Bianchi R. M.
- Biebel O.
- Biedermann D.
- Bielski R.
- Bierwagen K.
- Biesuz N. V.
- Biglietti M.
- Billoud T. R. V.
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- Bingul A.
- Bini C.
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- Birman M.
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- Biswal J. P.
- Biswas D.
- Bitadze A.
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- Blair R. E.
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- Bloch I.
- Blocker C.
- Blue A.
- Blumenschein U.
- Bobbink G. J.
- Bobrovnikov V. S.
- Bogavac D.
- Bogdan M.
- Bogdanchikov A. G.
- Bohm C.
- Boisvert V.
- Bokan P.
- Bold T.
- Bomben M.
- Bona M.
- Bonilla J. S.
- Boonekamp M.
- Booth C. D.
- Borbély A. G.
- Borecka-Bielska H. M.
- Borgna L. S.
- Borisov A.
- Borissov G.
- Bortoletto D.
- Boscherini D.
- Bosman M.
- Bossio Sola J. D.
- Bouaouda K.
- Boudreau J.
- Bouhova-Thacker E. V.
- Boumediene D.
- Bouquet R.
- Bourlis G.
- Boveia A.
- Boyd J.
- Boye D.
- Boyko I. R.
- Bozson A. J.
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- Brahimi N.
- Brandt G.
- Brandt O.
- Braren F.
- Brau B.
- Brau J. E.
- Breaden Madden W. D.
- Brendlinger K.
- Brener R.
- Brenner L.
- Brenner R.
- Bressler S.
- Brickwedde B.
- Briglin D. L.
- Britton D.
- Britzger D.
- Brock I.
- Brock R.
- Brooijmans G.
- Brooks W. K.
- Brost E.
- Bruckman de Renstrom P. A.
- Bruncko D.
- Bruni A.
- Bruni G.
- Bruschi M.
- Bruscino N.
- Bryant P.
- Bryngemark L.
- Brüers B.
- Buanes T.
- Buat Q.
- Buchholz P.
- Buckley A. G.
- Budagov I. A.
- Bugge M. K.
- Bulekov O.
- Bullard B. A.
- Burch T. J.
- Burdin S.
- Burgard C. D.
- Burger A. M.
- Burghgrave B.
- Burr J. T. P.
- Burton C. D.
- Burzynski J. C.
- Buschmann E.
- Bussey P. J.
- Butler J. M.
- Buttar C. M.
- Butterworth J. M.
- Buttinger W.
- Buxo Vazquez C. J.
- Buzykaev A. R.
- Büscher V.
- Cabras G.
- Cabrera Urbán S.
- Caforio D.
- Cai H.
- Cairo V. M. M.
- Cakir O.
- Calace N.
- Calafiura P.
- Calderini G.
- Calfayan P.
- Callea G.
- Caloba L. P.
- Caltabiano A.
- Calvente Lopez S.
- Calvet D.
- Calvet S.
- Calvet T. P.
- Calvetti M.
- Camacho Toro R.
- Camarda S.
- Camarero Munoz D.
- Camarri P.
- Camerlingo M. T.
- Cameron D.
- Camincher C.
- Campana S.
- Campanelli M.
- Camplani A.
- Canale V.
- Canesse A.
- Cano Bret M.
- Cantero J.
- Cao Y.
- Capua M.
- Cardarelli R.
- Cardillo F.
- Carducci G.
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- Carney R. M. D.
- Caron S.
- Carquin E.
- Carratta G.
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- Castillo Gimenez V.
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- Castro N. F.
- Catinaccio A.
- Catmore J. R.
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- Cavaliere V.
- Cavasinni V.
- Celebi E.
- Celli F.
- Cerny K.
- Cerqueira A. S.
- Cerri A.
- Cerrito L.
- Cerutti F.
- Cervelli A.
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- Chakraborty D.
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- Chan W. S.
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- Chapman J. D.
- Chargeishvili B.
- Charlton D. G.
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- Chatterjee M.
- Chau C. C.
- Chekanov S.
- Chekulaev S. V.
- Chelkov G. A.
- Chen B.
- Chen C.
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- Chen H.
- Chen H.
- Chen J.
- Chen J.
- Chen J.
- Chen S.
- Chen S. J.
- Chen X.
- Chen Y-H.
- Chen Y.
- Cheng H. C.
- Cheng H. J.
- Cheplakov A.
- Cheremushkina E.
- Cherkaoui El Moursli R.
- Cheu E.
- Cheung K.
- Chevalier L.
- Chevalérias T. J. A.
- Chiarella V.
- Chiarelli G.
- Chiodini G.
- Chisholm A. S.
- Chitan A.
- Chiu I.
- Chiu Y. H.
- Chizhov M. V.
- Choi K.
- Chomont A. R.
- Chou Y.
- Chow Y. S.
- Christopher L. D.
- Chu M. C.
- Chu X.
- Chudoba J.
- Chwastowski J. J.
- Cieri D.
- Ciesla K. M.
- Cindro V.
- Cioară I. A.
- Ciocio A.
- Cirotto F.
- Citraro S.
- Citron Z. H.
- Citterio M.
- Ciubotaru D. A.
- Ciungu B. M.
- Clark A.
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- Clawson S. E.
- Clement C.
- Clissa L.
- Coadou Y.
- Cobal M.
- Coccaro A.
- Cochran J.
- Coelho Lopes De Sa R.
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- Czurylo M. M.
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- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2021
- Field of study
The ATLAS Fast TracKer (FTK) was designed to provide full tracking for the ATLAS high-level trigger by using pattern recognition based on Associative Memory (AM) chips and fitting in high-speed field programmable gate arrays. The tracks found by the FTK are based on inputs from all modules of the pixel and silicon microstrip trackers. The as-built FTK system and components are described, as is the online software used to control them while running in the ATLAS data acquisition system. Also described is the simulation of the FTK hardware and the optimization of the AM pattern banks. An optimization for long-lived particles with large impact parameter values is included. A test of the FTK system with the data playback facility that allowed the FTK to be commissioned during the shutdown between Run 2 and Run 3 of the LHC is reported. The resulting tracks from part of the FTK system covering a limited η-ϕ region of the detector are compared with the output from the FTK simulation. It is shown that FTK performance is in good agreement with the simulation. © The ATLAS collaboratio
Prevalence and Correlates of Alcohol-Induced Blackouts Among College Students: Results of an E-Mail Survey
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Thigh-length compression stockings and DVT after stroke
- Author
- Abbas M
- Abbasi S
- Abbasi S
- Abdelaziz A
- Abdelfattah M
- Abdul B
- Abdulmumeen A
- Abdulshukkoor N
- Abdusamad K
- Aboaba A
- Abouibrahim M
- Abraham M
- Abraham T
- Abrams J
- Abung A
- Acharya D
- Acharya D
- Acheson J
- Acosta A
- Acosta A
- Acton C
- Adam M
- Adams C
- Adams K
- Adamus M
- Adegoke K
- Adenwalla S
- Adeyeye E
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- Thornton T
- Thorpe S
- Thozthumparambil P
- Thrasyvoulou L
- Thraves H
- Thwaites G
- Thwaites G
- Tiberi S
- Tierney C
- Tierney C
- Tilbey S
- Tiller A
- Timms H
- Tinkler H
- Tinkler M
- Tisi S
- Todd J
- Todd S
- Todd S
- Tohfa M
- Tomasova N
- Tomlin S
- Tomlinson J
- Topham K
- Torabi P
- Tousis R
- Tovey P
- Trafford MT
- Travill C
- Traynor S
- Trotter A
- Trudgill N
- Truslove M
- Trussell T
- Tsakiridou K
- Tsang C
- Tsilimpari K Karali
- Tucker S
- Tully R
- Turbitt K
- Turgut T
- Turnbull A
- Turner A
- Turner A
- Turner C
- Turner G
- Turner H
- Turner K
- Turner K
- Turner L
- Turner S
- Turney S
- Twohey E
- Tyagi B
- Tyagi V
- Tyer A
- Tzavaras P
- Uddin M Saif
- Ul Hassan W
- Ullah S
- Ullah S
- Umaipalan A
- Umeojiako W
- Unsworth A
- Uppal V Singh
- Urruela S
- Usher M
- Usher R
- Ustianowski A
- Ustianowski A
- Vaccari L Cheyenne
- Valeria B
- Vamplew L
- van de Venne M
- van der Meer A
- van der Stelt N
- van Someren C
- Vankayalapati P
- Vara S
- Varghese A
- Varghese M
- Varnier G
- Vasadi V
- Vasu V
- Vasudevan V
- Vathenen R
- Vatish M
- Vattekkat R Renu
- Vayalaman H
- Vaz C
- Veale N
- Velan B
- Velauthar L
- Vella N
- Venables I
- Venditti M
- Venkataramakrishnan R
- Veres M
- Vergnano S
- Verma A
- Vertue M
- Vethanayagam N
- Vilimiene N
- Vinay S
- Vincent R
- Vincent R
- Visentin E
- Vithian K
- Vyras E
- Wadd S
- Waddington N
- Wadsworth K
- Wafa SEI
- Wagstaff D
- Wagstaff L
- Wahbi Z
- Wake R
- Wakefield E
- Wakefield H
- Wakeford W
- Wakinshaw F
- Walden A
- Walker C
- Walker I
- Walker K
- Walker L
- Walker L
- Walker M
- Walker S
- Wall E
- Wallendszus K
- Waller R
- Wallis G
- Wallis L
- Walsh D
- Walshaw L
- Walter D
- Walters H
- Walters J
- Walton E
- Walton E
- Walton M
- Walton M
- Wan M
- Wan T
- Wands M
- Wane R
- Wang N
- Wang R
- Warburton S
- Ward E
- Ward K
- Ward L
- Ward R
- Ward T
- Warden S Andrew
- Wardle S
- Wardy H
- Warmington J
- Warner B
- Warner C
- Warren Y
- Watchorn HJ
- Waterfall H
- Waters A
- Waterstone M
- Watkins L
- Watson AJR
- Watson E
- Watson E
- Watson R
- Watters M
- Watterson D
- Watts M
- Waugh V
- Wayman E
- Weatherly N
- Webster I
- Webster T
- Weerasinghe T
- Weeratunga J
- Weetman M
- Wei S
- Welch J
- Welch S
- Weller S
- Wells C
- Welsh R
- Welters I
- Wentworth L
- Wessex D Porter
- West R
- West R
- Weston H
- Wetherall B
- Whileman A
- White C
- White D
- White J
- White J
- White M
- White S
- Whitehead C
- Whitehouse A
- Whitehouse T
- Whittaker E
- Whittam L
- Whittington A
- Wiafe E
- Wibli L
- Widdrington J
- Wiesender C
- Wiffen L
- Wight A
- Wilcock D
- Wilcock E
- Wild K
- Wild S
- Wilde M
- Wildsmith T
- Wiles J
- Wiles K
- Wiliams T
- Wilkinson I
- Wilkinson S
- Wilkinson S
- Willetts S
- Williams A
- Williams C
- Williams C
- Williams G
- Williams J
- Williams J
- Williams J
- Williams JR
- Williams K
- Williams K Barker
- Williams M
- Williams P
- Williams S
- Williams S
- Williams T
- Williamson C
- Williamson D
- Williamson J
- Willis E
- Willis H
- Willis H
- Willis J
- Willis J
- Wilson A
- Wilson A
- Wilson A
- Wilson D
- Wilson J
- Wilson J
- Wilson K
- Wilson L
- Wilson T
- Win M
- Winder L
- Winder P
- Winn S
- Winstanley M
- Winter H
- Winter J
- Wiselka M
- Wittes J
- Wolodimeroff E
- Wong N
- Wood C
- Wood F
- Wood J
- Wood L
- Wood T
- Woodford J
- Woodhead L
- Woodland P
- Woodward Z
- Wooldridge G
- Woollen L
- Woosey D
- Wootton D
- Worton S
- Wright D
- Wright R
- Wroe C
- Wu P
- Wyness K
- Wynter I
- Xavier B
- Xia Z
- Yan M
- Yanney M
- Yasmin S
- Yates B
- Yates B
- Yates D
- Yates H
- Yein K
- Yelnoorkar F
- Yip K
- Ynter I
- Yorke J
- Youssouf S
- Yousuf A
- Yung B
- Zafar A-M
- Zaher S
- Zalewska K
- Zaman M
- Zaman S
- Zammit L
- Zammit-Mangion M
- Zdanaviciene A
- Zehnde D
- Zhixin J
- Zhu D
- Zia M
- Zin E Thant
- Zinyemba V
- Zipitis C
- Zmierczak A
- Zuhra N
- Zulaikha R
- Zullo C
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/1994
- Field of study
Controversy exists as to whether neoadjuvant chemotherapy improves survival in patients with invasive bladder cancer, despite randomised controlled trials of more than 3000 patients. We undertook a systematic review and meta-analysis to assess the effect of such treatment on survival in patients with this disease
Craniotomy for Aneurysm
- Author
- A Asenjo
- A Bartal
- A Martinez Coll
- A Paterson
- A Paterson
- A Snellman
- A Uihlein
- A Yamaura
- AE Richardson
- AE Richardson
- AL Rhoton
- AL Rhoton
- AR Elvidge
- B Guidetti
- B Guidetti
- B Guidetti
- B Guidetti
- B Guidetti
- B Guidetti
- B Matricali
- B Pertuiset
- B Pertuiset
- B Selverstone
- B Woodhall
- CA Eisberg
- CB Sedzimir
- CB Shields
- CB Wilson
- CB Wilson
- CB Wilson
- CBT Adams
- CF List
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CH Sheldon
- CH Sheldon
- D Yashon
- DC Wright
- DH Wilson
- DJJ Klerk De
- DL Kasdon
- DR Malkasian
- DS Samson
- DWC Northfield
- E Böhm
- E Campbell
- E Laine
- E Laine
- E Laine
- E Laine
- E Laine
- E Trevani
- EF Lang
- EG Robertson
- EH Botterell
- EM Housepian
- ES Gurdjian
- F Garcia-Bengochea
- F Krause
- FHK Green
- FJ Gillingham
- G Björkesten af
- G Corkill
- G Guillain
- G Jefferson
- G Norlén
- G Norlén
- G Norlén
- G Norlén
- G Norlén
- G Norlén
- GC Stevenson
- GD VanderArk
- GD VanderArk
- GJ Hayes
- GJ Hayes
- GJ Heuer
- GJ Heuer
- GJ Heuer
- GL Viale
- GM Almeida
- GR Nugent
- H Dimsdale
- H Finkemyer
- H Gushing
- H Kikuchi
- H Krayenbühl
- H Krayenbühl
- H Krayenbühl
- H Krayenbühl
- H Nornes
- HF Steelman
- HG Schwartz
- HH Gass
- HSY Fang
- HV Rizzoli
- HW Pia
- I Strauss
- J Beau Le
- J Beau Le
- J Bonnal
- J Karasawa
- J Lepoire
- J Litvak
- J Ransohoff
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- JC Taylor
- JG McMurtry III
- JL Fox
- JL Fox
- JL Fox
- JL Fox
- JL Pool
- JL Pool
- JL Pool
- JL Pool
- JL Pool
- JL Pool
- JL Pool
- JL Poppen
- JL Poppen
- JL Poppen
- JL Salazar
- JM Taveras
- JP Wissinger
- JW Henderson
- K Hashi
- K Sano
- K Sano
- K Sano
- K Sugita
- K Sugita
- K Yada
- KG Jamieson
- KG Jamieson
- KG Jamieson
- KK Jain
- L Laitinen
- L Laitinen
- L Symon
- LA French
- LA French
- LA French
- LA French
- LA French
- LG Kempe
- LG Kempe
- LG Kempe
- LG Kempe
- M Brock
- M David
- M David
- M Prados
- MA Falconer
- MG Ya§argil
- MG Ya§argil
- MG Ya§argil
- MG Ya§argil
- MG Ya§argil
- MG Ya§argil
- MG Ya§argil
- MG Ya§argil
- MG Ya§argil
- MPAM Grood de
- N Avman
- N Whalley
- NM Dott
- O Höök
- O Höök
- P Frugoni
- P Harris
- P Harris
- PE Maspes
- R Deruty
- R Hemmer
- RC Bassett
- RD Swain
- RG Robinson
- RH Shephard
- RM Klemme
- RP Sengupta
- RS Rana
- RW Rand
- RW Rand
- S Endo
- S Hori
- S Thiry
- SA Hollin
- SJ Peerless
- SN Chou
- T Aiba
- T Aiba
- T Alajouanine
- T Hayakawa
- T Samorajski
- T Yoshimoto
- TJ Speakman
- TM Sundt Jr
- TM Sundt Jr
- V Logue
- W Tönnis
- W Tönnis
- W Tönnis
- W Usbeck
- WB Hamby
- WB Hamby
- WB Hamby
- WB Hamby
- WB Hamby
- WE Dandy
- WE Dandy
- WE Dandy
- WE Dandy
- WE Hitselberger
- WH Wright
- WJ Gardner
- WM Hammon
- WM Lougheed
- WM Lougheed
- WM Lougheed
- WM Lougheed
- Y Miyazaki
- Z Kunc
- Z Mraček
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1983
- Field of study
CXCR2 inhibition enables NASH-HCC immunotherapy
- Author
- Andreu-Oller Carmen
- Barry Simon T.
- Bird Thomas G.
- Carlin Leo M.
- Clark William
- Collins Amy
- Cortes-Lavaud Xabier
- Drake Thomas M.
- Esteban-Fabró Roger
- Fan Chaofan
- Fercoq Frédéric
- Filby Andrew
- Ford Catriona A.
- Fuller Andrew
- Geh Daniel
- Gilroy Kathryn
- Graham Gerard J.
- Haber Philipp K
- Hedley Ann
- Heikenwälder Mathias
- Hulme Gillian
- Jamieson Thomas
- Laszczewska Maja
- Leslie Jack
- Llovet Josep M
- Luli Saimir
- Mackey John B.G.
- Mann Derek A.
- McCain Misti V
- McDonald David
- McFarlane Amanda J
- Mohamed Noha-Ehssan
- Müller Miryam
- Nixon Colin
- Pfister Dominik
- Pinyol Roser
- Raffo Iraolagoitia Ximena L
- Rahbari Mohammad
- Raman Shreya
- Ramon-Gil Erik
- Reeves Helen L
- Ridgway Rachel A.
- Roberts Edward W.
- Sansom Owen J.
- Willoughby Catherine E
- Wilson Niall
- Publication venue
- 'BMJ'
- Publication date
- 27/04/2022
- Field of study
Objective: Hepatocellular carcinoma (HCC) is increasingly associated with non-alcoholic steatohepatitis (NASH). HCC immunotherapy offers great promise; however, recent data suggests NASH-HCC may be less sensitive to conventional immune checkpoint inhibition (ICI). We hypothesised that targeting neutrophils using a CXCR2 small molecule inhibitor may sensitise NASH-HCC to ICI therapy. Design: Neutrophil infiltration was characterised in human HCC and mouse models of HCC. Late-stage intervention with anti-PD1 and/or a CXCR2 inhibitor was performed in murine models of NASH-HCC. The tumour immune microenvironment was characterised by imaging mass cytometry, RNA-seq and flow cytometry. Results: Neutrophils expressing CXCR2, a receptor crucial to neutrophil recruitment in acute-injury, are highly represented in human NASH-HCC. In models of NASH-HCC lacking response to ICI, the combination of a CXCR2 antagonist with anti-PD1 suppressed tumour burden and extended survival. Combination therapy increased intratumoural XCR1+ dendritic cell activation and CD8+ T cell numbers which are associated with anti-tumoural immunity, this was confirmed by loss of therapeutic effect on genetic impairment of myeloid cell recruitment, neutralisation of the XCR1-ligand XCL1 or depletion of CD8+ T cells. Therapeutic benefit was accompanied by an unexpected increase in tumour-associated neutrophils (TANs) which switched from a protumour to anti-tumour progenitor-like neutrophil phenotype. Reprogrammed TANs were found in direct contact with CD8+ T cells in clusters that were enriched for the cytotoxic anti-tumoural protease granzyme B. Neutrophil reprogramming was not observed in the circulation indicative of the combination therapy selectively influencing TANs. Conclusion: CXCR2-inhibition induces reprogramming of the tumour immune microenvironment that promotes ICI in NASH-HCC
Prognosis and Timing
- Author
- A Bartal
- A Bloch
- A Dereymaeker
- A Martinez Coll
- A Paterson
- A Paterson
- A Uihlein
- AB Loach
- AE Richardson
- AE Richardson
- AE Richardson
- AE Richardson
- AE Richardson
- AJM Werf Van der
- AL Amacher
- AR Taylor
- AR Taylor
- AS Arutyunova
- AS Arutyunova
- AS Brown
- AS Fleischer
- AZ Keller
- B Bevan
- B Guidetti
- B Guidetti
- B Guidetti
- B Guidetti
- B Pertuiset
- B Pertuiset
- B Pertuiset
- B Prakash
- B Smith
- B Weir
- B Weir
- BM Bloor
- BM Marshall
- BM Nikiforov
- BW Nilsson
- C Arseni
- C Arseni
- C Arseni
- C Lapras
- CA Calvert
- CBT Adams
- CD Hawkes
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CH Hudson
- CH Millikan
- CJ Graf
- CJ Graf
- CJ Graf
- CJ Graf
- CM Fisher
- CM Fisher
- D Parkinson
- DC Austin
- DD Matson
- DF Benson
- DGT Thomas
- DM Kaufman
- DS Samson
- DS Samson
- DW Nibbelink
- DW Nibbelink
- DW Nibbelink
- DW Nibbelink
- E Alexander Jr
- E Boldrey
- E Böhm
- E Böhm
- E Böhm
- E Kágstróm
- E Laine
- E Laine
- EC Alvord Jr
- EC Alvord Jr
- EF Lang
- EG Robertson
- EH Botterell
- EI Zlotnik
- FA Cioffi
- FA Cioffi
- FJ Gillingham
- FJ Gillingham
- FJ Gillingham
- FL Deborsu
- FM Skultety
- FM Skultety
- G Allégre
- G Björkesten af
- G Björkesten af
- G Björkesten af
- G Boulay du
- G Boulay du
- G Corkill
- G Corkill
- G Duffy
- G Marini
- G Morello
- G Norlén
- G Norlén
- G Norlén
- G Norlén
- G Norlén
- GH Dickmann
- GL Odom
- GT Tindall
- H Abe
- H Fodstad
- H Gass
- H Kikuchi
- H Kikuchi
- H Kim
- H Krayenbuhl
- H Krayenbühl
- H Krayenbühl
- H Krayenbühl
- H Krayenbühl
- H Niizuma
- H Nishioka
- H Nishioka
- H Nornes
- H Nornes
- H Nornes
- H Troupp
- H Troupp
- H Troupp
- HB Griffith
- HB Locksley
- HB Locksley
- HE Hunt
- HH Hyland
- HJ Gelmers
- HR Winn
- HR Winn
- HR Winn
- HT Ballantine Jr
- I Saito
- I Saito
- I Saito
- I Saito
- I Saito
- IM James
- J Beau Le
- J Beau Le
- J Bonnal
- J Bonnal
- J Bonnal
- J Bromowicz
- J Cophignon
- J Cophignon
- J Hanau
- J Karasawa
- J Ransohoff
- J Ransohoff
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- J Suzuki
- JA Jane
- JC Torner
- JD Parkes
- JG Galbraith
- JG McMurtry
- JG Roberts
- JH Trumpy
- JL Fox
- JL Fox
- JL Fox
- JL Fox
- JL Pool
- JL Pool
- JL Pool
- JL Pool
- JL Pool
- JL Pool
- JL Pool
- JL Pool
- JL Poppen
- JL Poppen
- JL Poppen
- JN Walton
- JS Tytus
- JTE Richardson
- JW Magladery
- JWD Bull
- K Clark
- K Ito
- K Sano
- K Sano
- K Sano
- K Sano
- K Sano
- K Shulman
- KD Post
- KG Jamieson
- KG Jamieson
- KK Jain
- L Ectors
- L Infuso
- L Laitinen
- L Symon
- L Symon
- L Symon
- L Symon
- L Symon
- L Symon
- L Walsh
- LA French
- LA French
- LA Hazouri
- LA Klafta Jr
- LA Klafta Jr
- LA Klafta Jr
- LA Mount
- LA Mount
- LA Mount
- LH Pitts
- LH Zingesser
- LH Zingesser
- LS Walsh
- M David
- M David
- M Kaste
- M Klinlger
- M Kutsuna
- M Orozco
- M Romy
- M Sachs
- M Tappura
- MA Falconer
- MG Yaşargil
- MG Yaşargil
- MG Yaşargil
- MP Heilbrun
- MP Heilbrun
- NH Horwitz
- NM Dott
- NT Mathew
- O Heiskanen
- O Heiskanen
- O Hook
- O Hook
- O Hook
- O Sugar
- OJ Beck
- OM Ballenger
- P Castaigne
- P Frugoni
- P Frugoni
- P Karlsberg
- P Niemeyer
- P Rousseaux
- PE Maspes
- PE Maspes
- PE Maspes
- PJ Kelly
- PJ Kelly
- PS Slosberg
- R Braakman
- R Deruty
- R Fujinaga
- R Galera
- R Hugosson
- R Hugosson
- R Ishii
- R Ishii
- R Kwak
- R Maurice-Williams
- RA Davis
- RAC Jones
- RC Bassett
- RG Robinson
- RH Ahmed
- RH Dunsmore
- RH Miller
- RH Wilkins
- RH Wilkins
- RH Wilkins
- RL Grubb
- RL Paul
- RP Sengupta
- RP Sengupta
- RP Sengupta
- S Cambria
- S Cotsou
- S Hori
- S Mingrino
- S Mullan
- S Pakarinen
- S Rohe
- SA Hollin
- SA Hollin
- SA Schneck
- SA Schneck
- SJ Goodman
- SL Giannotta
- SN Chou
- SN Rowe
- T Fukumitsu
- T Kayama
- T Kutsuzawa
- T Onuma
- T Onuma
- T Yoshimoto
- TAR Dinning
- TM Fletcher
- TM Sundt Jr
- TM Sundt Jr
- TM Sundt Jr
- TP Morley
- V Charlez
- V Logue
- V Logue
- V Logue
- VK Kak
- W Heitler
- W McKissock
- W McKissock
- W McKissock
- W McKissock
- W Sencer
- W Tönnis
- W Walter
- WB Hamby
- WB Hamby
- WB Hamby
- WB Hamby
- WB Hamby
- WB Hamby
- WB Hamby
- WB Hamby
- WE Dandy
- WE Dandy
- WE Hunt
- WE Hunt
- WE Hunt
- WE Hunt
- WE Hunt
- WF McCormick
- WG Henderson
- WH Marshall Jr
- WL Bailey
- WM Lougheed
- WM Lougheed
- WM Lougheed
- WM Lougheed
- WM Lougheed
- WW Stevens
- Y Sakurai
- Y Sakurai
- É Orosz
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1983
- Field of study
Craniotomy for Aneurysm
- Author
- A Bartal
- A Bouchet
- A Decker
- A Hockley
- A Hockley
- A Martinez Coll
- A Nakahara
- A Shintani
- A Uihlein
- A Uihlein
- AA McConnell
- AG Fingerhut
- AJ Luessenhop
- AJ Luessenhop
- AL Amacher
- AL Rhoton
- AN Guthkelch
- AR Choudhury
- AR Taylor
- AS Genest
- AW Auld
- AW Cook
- B Aarobi
- B Guidetti
- B Guidetti
- B Guidetti
- B Guidetti
- B Hughes
- B Pertuiset
- B Pertuiset
- B Pertuiset
- B Pertuiset
- B Schlosshauer
- B Smith
- B Woodhall
- B Woodhall
- BA Samotokin
- BC Einspruch
- BJ Ammerman
- BR Gelber
- C Araki
- C Arseni
- C Arseni
- C Bhushan
- C Gros
- C Kerber
- CA Elsberg
- CA Fager
- CB Early
- CB Wilson
- CF List
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CG Drake
- CHH Baumann
- CJ Graf
- CK Rüssel
- CMH Howell
- CP Symonds
- D Parkinson
- D Parkinson
- D Parkinson
- D Petit-Dutaillis
- D Sashin
- D Sashin
- DD Matson
- DJ Prolo
- DJ Prolo
- DM Dooley
- E Bohm
- E Campbell
- E Frantzen
- E Laine
- E Laine
- EC Hann
- EF Fincher
- EG Robertson
- EI Kandel
- EI Kandel
- EL Gage
- F Durity
- F Garcia-Bengochea
- F Heppner
- F Heppner
- F Kennedy
- F Weickmann
- FA Serbinenko
- FD Snyckers
- FJ Gillingham
- FM Skultety
- FM Skultety
- G Bjorkesten Af
- G Debrun
- G Debrun
- G Debrun
- G Debrun
- G Debrun
- G Debrun
- G Debrun
- G Jefferson
- G Jefferson
- G Lazorthes
- G Maira
- G Maira
- G Morello
- G Norlén
- G Norlén
- G Norlén
- G Norlén
- G Paulson
- GF Rowbotham
- GG Ferguson
- GG Ferguson
- GJ Heuer
- GL Gryspeerdt
- GL Viale
- GM Almeida
- GR Hoffman
- GT Tindall
- GT Tindall
- H Cushing
- H Dimsdale
- H Fodstad
- H Hugenholtz
- H Krayenbühl
- H Nornes
- H Nornes
- H Nukui
- H Verbiest
- H-D Herrmann
- HA Crockard
- HA Krayenbühl
- HAD Walder
- HD Kirgis
- HD Kirgis
- HF Steelman
- HH Gass
- HJ Denecke
- HL Cares
- HL Rosomoff
- HR Schaeffer
- HT Glaser
- HV Rizzoli
- HW Dueker
- HW Pia
- I Hallac
- IZ Kosary
- J Bonnal
- J Bonnal
- J Bonnal
- J Cophignon
- J Cophignon
- J Feigenbaum
- J Greenwood Jr
- J Guillaume
- J Karasawa
- J Overgaard
- J Rougerie
- J Seltzer
- J Suzuki
- J Suzuki
- J Suzuki
- J Weibel
- J-J Santini
- JA Taren
- JA Taren
- JC Maroon
- JE Adams
- JE Paillas
- JF Alksne
- JF Alksne
- JF Alksne
- JF Alksne
- JF Alksne
- JF Alksne
- JF Alksne
- JF Alksne
- JG Hamilton
- JH Taeffner
- JL Fox
- JL Fox
- JL Fox
- JL Fox
- JL Fox
- JL Pool
- JL Pool
- JL Pool
- JL Poppen
- JL Poppen
- JL Poppen
- JL Poppen
- JL Poppen
- JL Poppen
- JM Allcock
- JM Dixon
- JO Stallings
- JP Gallagher
- JP Gallagher
- JP Gallagher
- JP Gallagher
- JP Kapp
- JR Gibbs
- JR Wennerstrand
- JRM Klemme
- JS Tytus
- JT McFadden
- JW Henderson
- K Hashi
- K Hermann
- K Kusaka
- K Sano
- KG Jamieson
- KG McKenzie
- KH Abbott
- L Bakay
- L Laitinen
- L Laitinen
- L Laitinen
- L Perria
- L Perria
- L Picard
- L Steiner
- LA French
- LA French
- LA French
- LA French
- LA French
- LA French
- LA Hazouri
- LA Mount
- LA Mount
- LG Kempe
- LN Hopkins
- Lyerly
- M Borchardt
- M David
- M Miyazaki
- M Packard
- M Scott
- M Scott
- MA Falcojier
- MA Falconer
- MA Falconer
- MA Falconer
- MA Falconer
- MC Sosman
- MG Yaşargil
- MG Yaşargil
- MG Yaşargil
- MG Yaşargil
- MG Yaşargil
- MG Yaşargil
- MH Wholey
- MH Wholey
- MM Peet
- MR Crompton
- MV DiTullio Jr
- MV DiTullio Jr
- N Whalley
- NM Dott
- O Foerster
- O Hôôk
- O Hôôk
- O Hôôk
- O Sjoqvist
- O Sugar
- OA Turner
- OH Reichman
- P Harris
- P Tangehai
- PE Sheptak
- PH Zanetti
- PN Sawyer
- R Jaeger
- R Pian Di
- R Rousseaux
- RA Davis
- RA Groff
- RA Rozario
- RC Bassett
- RC Bassett
- RC Bassett
- RD Swain
- RF Spetzler
- RH Ahmed
- RH Patterson Jr
- RL DeSaussure De
- RL Paul
- RP Kikut
- RS Rana
- RW Rand
- RW Rand
- RW Smith
- S Kamano
- S Mullan
- S Mullan
- S Mullan
- S Mullan
- S Mullan
- S Mullan
- S Mullan
- S Nystrôm
- S Okawara
- S Sakaki
- S Thiry
- SB Fierstien
- SB Yodh
- SC Werner
- SE Moolten
- SF Rothenberg
- SJ Peerless
- SK Hilal
- SK Hilal
- SN Chou
- SN Rowe
- T Aiba
- T Iwabuchi
- T Ohta
- T Sakaki
- TJ Rosenbaum
- TM Sundt Jr
- TM Sundt Jr
- TP Morley
- V Dolenc
- V Logue
- V Logue
- W Grote
- W Magner
- W Sencer
- W Taki
- W Taki
- W Tônnis
- WB Hamby
- WB Hamby
- WB Hamby
- WB Hamby
- WB Hamby
- WB Hamby
- WE Bell
- WE Dandy
- WE Dandy
- WE Dandy
- WE Dandy
- WE Dandy
- WE Dandy
- WE Dandy
- WE Hunt
- WJ Atkinson
- WJ Atkinson
- WJ Gardner
- WJ German
- WM Lougheed
- WM Lougheed
- WM Lougheed
- WO Bank
- Y Hosobuchi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1983
- Field of study
Childhood risk factors for personality disorder symptoms related to violence
- Author
- Alex R. Piquero
- Alwin
- American Psychiatric Association
- American Psychiatric Association
- Armstrong
- Baglivio
- Battle
- Baumeister
- Bebbington
- Becker
- Benjamin
- Berenz
- Berking
- Bernstein
- Bielas
- Blackburn
- Blackburn
- Brennan
- Ciubara
- Cohen
- Cohen
- Coid
- Coid
- Coid
- Coid
- Coid
- Coid
- Coid
- Coid
- Coid
- Cunha
- David P. Farrington
- Day
- De Barros
- De Clercq
- Douglas
- Drake
- Dube
- Duggan
- Dunne
- Eisenberg
- Eronen
- Esbec
- Esbec
- Esbec
- Farrington
- Farrington
- Farrington
- Farrington
- Fazel
- First
- Fisher
- Ford
- Ford
- Fossati
- Fox
- Freestone
- Gibbon
- Gibson
- Gilbert
- Girolamo
- Golier
- Gotlib
- Hengartner
- Hill
- Hodgins
- Horowitz
- Howard
- James
- Jamieson
- Jeremy W. Coid
- Johnson
- Johnson
- Johnson
- Joyce
- Keeney
- Keulen-de Vos
- Kim Reising
- Krug
- Logan
- Logan
- Logan
- Lowenstein
- Luntz
- Maria M. Ttofi
- McLean
- McLeod
- Millon
- Nestor
- Newton-Howes
- Novaco
- Office for National Statistics
- Ogata
- Paris
- Paris
- Paris
- Piquero
- Piquero
- Piquero
- Piquero
- Piquero
- Putkonen
- Rettew
- Roberts
- Roberts
- Ross
- Samuels
- Scott
- Seidel
- Singleton
- Spataro
- Stone
- Strine
- Timmerman
- Trull
- Tyrer
- Ullrich
- Ullrich
- Van Dijke
- Van Dijke
- Van Dijke
- Volkert
- Wallace
- Weeks
- Widiger
- Widom
- Winograd
- World Health Organization
- Yen
- Yu
- Zhang
- Zimmerman
- Zweig
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study