2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: executive summary.

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2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: executive summary.

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withdrawn 2017 hrs ehra ecas aphrs solaece expert consensus statement on catheter and surgical ablation of atrial fibrillation

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The Value of Failure in Science: The Story of Grandmother Cells in Neuroscience

The annals of science are filled with successes. Only in footnotes do we hear about the failures, the cul-de-sacs, and the forgotten ideas. Failure is how research advances. Yet it hardly features in theoretical perspectives on science. That is a mistake. Failures, whether clear-cut or ambiguous, are heuristically fruitful in their own right. Thinking about failure questions our measures of success, including the conceptual foundations of current practice, that can only be transient in an experimental context. This article advances the heuristics of failure analysis, meaning the explicit treatment of certain ideas or models as failures. The value of failures qua being a failure is illustrated with the example of grandmother cells; the contested idea of a hypothetical neuron that encodes a highly specific but complex stimulus, such as the image of one’s grandmother. Repeatedly evoked in popular science and maintained in textbooks, there is sufficient reason to critically review the theoretical and empirical background of this idea

Design of a 3D-printed, open-source wrist-driven orthosis for individuals with spinal cord injury

<div><p>Assistive technology, such as wrist-driven orthoses (WDOs), can be used by individuals with spinal cord injury to improve hand function. A lack of innovation and challenges in obtaining WDOs have limited their use. These orthoses can be heavy and uncomfortable for users and also time-consuming for orthotists to fabricate. The goal of this research was to design a WDO with user (N = 3) and orthotist (N = 6) feedback to improve the accessibility, customizability, and function of WDOs by harnessing advancements in 3D-printing. The 3D-printed WDO reduced hands-on assembly time to approximately 1.5 hours and the material costs to $15 compared to current fabrication methods. Varying improvements in users' hand function were observed during functional tests, such as the Jebsen Taylor Hand Function Test. For example, one participant's ability on the small object task improved by 29 seconds with the WDO, while another participant took 25 seconds longer to complete this task with the WDO. Two users had a significant increase in grasp strength with the WDO (13–122% increase), while the other participant was able to perform a pinching grasp for the first time. The WDO designs are available open-source to increase accessibility and encourage future innovation.</p></div

Metal and 3D-printed WDOs.

<p>(A) Traditional WDO fabricated from the Jaeco kit. (B) 3D-printed WDO from this research.</p

The experimental setup of the study with 3D-printed WDOs.

<p>(A) P&O student fabricating a 3D-printed WDO using the device manual. (B) User performs the writing task of the JTHF test with a 3D-printed WDO.</p

Design of a 3D-printed, open-source wrist-driven orthosis for individuals with spinal cord injury - Fig 3

<p><b>Exploded (A) and assembled (B) view of the CAD model of the 11 pieces of the 3D-printed WDO</b>.</p